TreeWAS – Variant ID: rs11135380

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Showing all nodes without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
Chapter XV Pregnancy, childbirth and the puerperium	0.411	0.589	0.000
Chapter II Neoplasms	0.405	0.595	0.000
# Top node	0.404	0.596	0.000
O20-O29 Other maternal disorders predominantly related to pregnancy	0.400	0.600	0.000
Chapter X Diseases of the respiratory system	0.395	0.605	0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.394	0.606	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.393	0.607	0.000
O80-O84 Delivery	0.391	0.609	0.000
C43-C44 Melanoma and other malignant neoplasms of skin	0.386	0.614	0.000
Chapter I Certain infectious and parasitic diseases	0.382	0.618	0.000
J09-J18 Influenza and pneumonia	0.381	0.619	0.000
Chapter XX External causes of morbidity and mortality	0.380	0.620	0.000
O80 Single spontaneous delivery	0.378	0.622	0.000
C44 Other malignant neoplasms of skin	0.377	0.623	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.375	0.625	0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.373	0.627	0.000
C44.3 Skin of other and unspecified parts of face	0.370	0.630	0.000
J18 Pneumonia, organism unspecified	0.369	0.631	0.000
D23 Other benign neoplasms of skin	0.368	0.632	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.367	0.633	0.000
J18.1 Lobar pneumonia, unspecified	0.367	0.633	0.000
D10-D36 Benign neoplasms	0.365	0.635	0.000
S00-S09 Injuries to the head	0.364	0.636	0.000
D00-D09 In situ neoplasms	0.359	0.641	0.000
Chapter VIII Diseases of the ear and mastoid process	0.358	0.642	0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified	0.358	0.642	0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.357	0.643	0.000
O80.0 Spontaneous vertex delivery	0.357	0.643	0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.351	0.649	0.000
O20 Haemorrhage in early pregnancy	0.351	0.649	0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.350	0.650	0.000
O24 Diabetes mellitus in pregnancy	0.349	0.651	0.000
J90-J94 Other diseases of pleura	0.349	0.651	0.000
J60-J70 Lung diseases due to external agents	0.348	0.652	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.347	0.653	0.000
T51 Toxic effect of alcohol	0.346	0.654	0.000
D37-D48 Neoplasms of uncertain or unknown behaviour	0.346	0.654	0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.345	0.655	0.000
A00-A09 Intestinal infectious diseases	0.344	0.656	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.343	0.657	0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.343	0.657	0.000
D23.1 Skin of eyelid, including canthus	0.341	0.659	0.000
O00-O08 Pregnancy with abortive outcome	0.339	0.661	0.000
S01 Open wound of head	0.337	0.663	0.000
S80-S89 Injuries to the knee and lower leg	0.337	0.663	0.000
Y44 Agents primarily affecting blood constituents	0.336	0.664	0.000
T51.0 Ethanol	0.336	0.664	0.000
J95-J99 Other diseases of the respiratory system	0.335	0.665	0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.332	0.668	0.000
D14 Benign neoplasm of middle ear and respiratory system	0.332	0.668	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.331	0.669	0.000
J91 Pleural effusion in conditions classified elsewhere	0.330	0.670	0.000
D23.5 Skin of trunk	0.329	0.671	0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.329	0.671	0.000
C44.9 Malignant neoplasm of skin, unspecified	0.327	0.672	0.000
C90 Multiple myeloma and malignant plasma cell neoplasms	0.327	0.673	0.000
O32 Maternal care for known or suspected malpresentation of foetus	0.326	0.674	0.000
A04 Other bacterial intestinal infections	0.325	0.675	0.000
X60-X84 Intentional self-harm	0.325	0.675	0.000
S00 Superficial injury of head	0.322	0.678	0.000
H65-H75 Diseases of middle ear and mastoid	0.322	0.678	0.000
C44.5 Skin of trunk	0.320	0.679	0.000
O20.0 Threatened abortion	0.320	0.680	0.000
D23.7 Skin of lower limb, including hip	0.320	0.680	0.000
O23 Infections of genito-urinary tract in pregnancy	0.319	0.681	0.000
B15-B19 Viral hepatitis	0.319	0.681	0.000
D04 Carcinoma in situ of skin	0.319	0.681	0.000
O80.9 Single spontaneous delivery, unspecified	0.318	0.681	0.000
O04 Medical abortion	0.317	0.683	0.000
H60-H62 Diseases of external ear	0.315	0.685	0.000
J00-J06 Acute upper respiratory infections	0.315	0.685	0.000
D31 Benign neoplasm of eye and adnexa	0.314	0.685	0.000
D32 Benign neoplasm of meninges	0.314	0.686	0.000
S32 Fracture of lumbar spine and pelvis	0.314	0.686	0.000
O32.1 Maternal care for breech presentation	0.313	0.687	0.000
D23.6 Skin of upper limb, including shoulder	0.313	0.687	0.000
O16 Unspecified maternal hypertension	0.311	0.689	0.000
A04.8 Other specified bacterial intestinal infections	0.311	0.689	0.000
B35-B49 Mycoses	0.310	0.690	0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.310	0.690	0.000
O28 Abnormal findings on antenatal screening of mother	0.309	0.691	0.000
C91 Lymphoid leukaemia	0.309	0.691	0.000
Chapter XII Diseases of the skin and subcutaneous tissue	0.308	0.692	0.000
Y44.2 Anticoagulants	0.308	0.692	0.000
D14.0 Middle ear, nasal cavity and accessory sinuses	0.308	0.692	0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.307	0.693	0.000
C45 Mesothelioma	0.307	0.693	0.000
O26 Maternal care for other conditions predominantly related to pregnancy	0.305	0.695	0.000
Y52 Agents primarily affecting the cardiovascular system	0.305	0.695	0.000
X58-X59 Accidental exposure to other and unspecified factors	0.303	0.697	0.000
S01.8 Open wound of other parts of head	0.303	0.697	0.000
O21 Excessive vomiting in pregnancy	0.302	0.697	0.000
C92 Myeloid leukaemia	0.302	0.697	0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.301	0.699	0.000
J18.8 Other pneumonia, organism unspecified	0.300	0.699	0.000
C44.7 Skin of lower limb, including hip	0.300	0.700	0.000
O04.9 Complete or unspecified, without complication	0.300	0.700	0.000
A50-A64 Infections with a predominantly sexual mode of transmission	0.299	0.701	0.000
D47.2 Monoclonal gammopathy	0.298	0.702	0.000
T17 Foreign body in respiratory tract	0.298	0.702	0.000
J15 Bacterial pneumonia, not elsewhere classified	0.298	0.702	0.000
D03 Melanoma in situ	0.298	0.702	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.297	0.702	0.000
B25-B34 Other viral diseases	0.297	0.703	0.000
S01.3 Open wound of ear	0.296	0.704	0.000
O24.0 Pre-existing diabetes mellitus, insulin-dependent	0.296	0.704	0.000
J11 Influenza, virus not identified	0.295	0.705	0.000
Y45.8 Other analgesics and antipyretics	0.295	0.705	0.000
O85-O92 Complications predominantly related to the puerperium	0.294	0.706	0.000
S40-S49 Injuries to the shoulder and upper arm	0.293	0.707	0.000
O94-O99 Other obstetric conditions, not elsewhere classified	0.293	0.707	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.292	0.708	0.000
W00-W19 Falls	0.291	0.709	0.000
C40-C41 Malignant neoplasms of bone and articular cartilage	0.291	0.709	0.000
S00.0 Superficial injury of scalp	0.290	0.710	0.000
Q80-Q89 Other congenital malformations	0.290	0.710	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.290	0.710	0.000
C64-C68 Malignant neoplasms of urinary tract	0.290	0.710	0.000
C09 Malignant neoplasm of tonsil	0.289	0.711	0.000
H65 Nonsuppurative otitis media	0.289	0.711	0.000
D23.4 Skin of scalp and neck	0.289	0.711	0.000
Y51 Drugs primarily affecting the autonomic nervous system	0.288	0.712	0.000
C49 Malignant neoplasm of other connective and soft tissue	0.288	0.712	0.000
S50-S59 Injuries to the elbow and forearm	0.288	0.712	0.000
D09 Carcinoma in situ of other and unspecified sites	0.287	0.712	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.287	0.713	0.000
J61 Pneumoconiosis due to asbestos and other mineral fibres	0.287	0.713	0.000
S01.5 Open wound of lip and oral cavity	0.287	0.713	0.000
O29 Complications of anaesthesia during pregnancy	0.287	0.713	0.000
O22 Venous complications in pregnancy	0.287	0.713	0.000
O25 Malnutrition in pregnancy	0.287	0.713	0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.287	0.713	0.000
O80.8 Other single spontaneous delivery	0.287	0.713	0.000
X20-X29 Contact with venomous animals and plants	0.287	0.713	0.000
J30-J39 Other diseases of upper respiratory tract	0.286	0.714	0.000
O47 False labour	0.286	0.714	0.000
X40-X49 Accidental poisoning by and exposure to noxious substances	0.286	0.714	0.000
D06 Carcinoma in situ of cervix uteri	0.286	0.714	0.000
Y57 Other and unspecified drugs and medicaments	0.285	0.714	0.000
D29 Benign neoplasm of male genital organs	0.285	0.715	0.000
T79-T79 Certain early complications of trauma	0.285	0.715	0.000
H61 Other disorders of external ear	0.285	0.715	0.000
S81 Open wound of lower leg	0.285	0.715	0.000
S80 Superficial injury of lower leg	0.284	0.716	0.000
S90-S99 Injuries to the ankle and foot	0.284	0.716	0.000
J10 Influenza due to identified influenza virus	0.284	0.716	0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.284	0.716	0.000
D47.1 Chronic myeloproliferative disease	0.283	0.717	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.283	0.717	0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.283	0.717	0.000
C95 Leukaemia of unspecified cell type	0.283	0.717	0.000
C94 Other leukaemias of specified cell type	0.283	0.717	0.000
C93 Monocytic leukaemia	0.283	0.717	0.000
C88 Malignant immunoproliferative diseases	0.283	0.717	0.000
C86 Other specified types of T/NK-cell lymphoma	0.283	0.717	0.000
C84 Peripheral and cutaneous T-cell lymphomas	0.283	0.717	0.000
D33 Benign neoplasm of brain and other parts of central nervous system	0.283	0.717	0.000
J95 Postprocedural respiratory disorders, not elsewhere classified	0.282	0.718	0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.282	0.718	0.000
S06 Intracranial injury	0.282	0.718	0.000
T33-T35 Frostbite	0.282	0.718	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.282	0.718	0.000
T00-T07 Injuries involving multiple body regions	0.282	0.718	0.000
O24.4 Diabetes mellitus arising in pregnancy	0.282	0.718	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.281	0.718	0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.281	0.719	0.000
J93 Pneumothorax	0.281	0.719	0.000
Y60-Y69 Misadventures to patients during surgical and medical care	0.281	0.719	0.000
S70-S79 Injuries to the hip and thigh	0.281	0.719	0.000
C81 Hodgkin's disease	0.280	0.719	0.000
O84 Multiple delivery	0.280	0.720	0.000
O83 Other assisted single delivery	0.280	0.720	0.000
O81 Single delivery by forceps and vacuum extractor	0.280	0.720	0.000
Y41 Other systemic anti-infectives and antiparasitics	0.280	0.720	0.000
O26.9 Pregnancy-related condition, unspecified	0.280	0.720	0.000
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx	0.280	0.720	0.000
D23.2 Skin of ear and external auricular canal	0.279	0.720	0.000
C83 Diffuse non-Hodgkin's lymphoma	0.279	0.721	0.000
C44.1 Skin of eyelid, including canthus	0.279	0.721	0.000
T63 Toxic effect of contact with venomous animals	0.279	0.721	0.000
J14 Pneumonia due to Haemophilus influenzae	0.279	0.721	0.000
X50-X57 Overexertion, travel and privation	0.278	0.722	0.000
J69 Pneumonitis due to solids and liquids	0.277	0.722	0.000
O35 Maternal care for known or suspected foetal abnormality and damage	0.277	0.723	0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.277	0.723	0.000
T66-T78 Other and unspecified effects of external causes	0.276	0.724	0.000
C90.2 Plasmacytoma, extramedullary	0.276	0.724	0.000
J92 Pleural plaque	0.275	0.725	0.000
A04.5 Campylobacter enteritis	0.274	0.725	0.000
D36 Benign neoplasm of other and unspecified sites	0.274	0.726	0.000
D30 Benign neoplasm of urinary organs	0.274	0.726	0.000
B99-B99 Other infectious diseases	0.274	0.726	0.000
B90-B94 Sequelae of infectious and parasitic diseases	0.274	0.726	0.000
B85-B89 Pediculosis, acariasis and other infestations	0.274	0.726	0.000
B50-B64 Protozoal diseases	0.274	0.726	0.000
B20-B24 Human immunodeficiency virus [HIV] disease	0.274	0.726	0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.274	0.726	0.000
A75-A79 Rickettsioses	0.274	0.726	0.000
A70-A74 Other diseases caused by chlamydiae	0.274	0.726	0.000
A65-A69 Other spirochaetal diseases	0.274	0.726	0.000
A20-A28 Certain zoonotic bacterial diseases	0.274	0.726	0.000
A15-A19 Tuberculosis	0.274	0.726	0.000
S32.5 Fracture of pubis	0.273	0.727	0.000
D04.5 Skin of trunk	0.273	0.727	0.000
J17 Pneumonia in diseases classified elsewhere	0.273	0.727	0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified	0.273	0.727	0.000
J12 Viral pneumonia, not elsewhere classified	0.273	0.727	0.000
J09 Influenza due to certain identified influenza virus	0.273	0.727	0.000
B02 Zoster [herpes zoster]	0.273	0.727	0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.273	0.727	0.000
Y35-Y36 Legal intervention and operations of war	0.272	0.727	0.000
Y10-Y34 Event of undetermined intent	0.272	0.727	0.000
Y00-Y09 Assault	0.272	0.727	0.000
X85-X99 Assault	0.272	0.727	0.000
X30-X39 Exposure to forces of nature	0.272	0.727	0.000
X10-X19 Contact with heat and hot substances	0.272	0.727	0.000
X00-X09 Exposure to smoke, fire and flames	0.272	0.727	0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.272	0.727	0.000
W75-W84 Other accidental threats to breathing	0.272	0.727	0.000
W65-W74 Accidental drowning and submersion	0.272	0.727	0.000
W50-W64 Exposure to animate mechanical forces	0.272	0.727	0.000
V98-V99 Other and unspecified transport accidents	0.272	0.727	0.000
V95-V97 Air and space transport accidents	0.272	0.727	0.000
V90-V94 Water transport accidents	0.272	0.727	0.000
V70-V79 Bus occupant injured in transport accident	0.272	0.727	0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.272	0.727	0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.272	0.727	0.000
V40-V49 Car occupant injured in transport accident	0.272	0.727	0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.272	0.727	0.000
V01-V09 Pedestrian injured in transport accident	0.272	0.727	0.000
B65-B83 Helminthiases	0.272	0.728	0.000
S10-S19 Injuries to the neck	0.272	0.728	0.000
J67 Hypersensitivity pneumonitis due to organic dust	0.272	0.728	0.000
D26 Other benign neoplasms of uterus	0.272	0.728	0.000
C04 Malignant neoplasm of floor of mouth	0.272	0.728	0.000
O80.1 Spontaneous breech delivery	0.271	0.729	0.000
V80-V89 Other land transport accidents	0.271	0.729	0.000
B18 Chronic viral hepatitis	0.270	0.730	0.000
C44.8 Overlapping lesion of skin	0.270	0.730	0.000
A08 Viral and other specified intestinal infections	0.270	0.730	0.000
Y45.2 Propionic acid derivatives	0.270	0.730	0.000
O82 Single delivery by Caesarean section	0.269	0.730	0.000
Y59 Other and unspecified vaccines and biological substances	0.269	0.731	0.000
Y58 Bacterial vaccines	0.269	0.731	0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.269	0.731	0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.269	0.731	0.000
Y53 Agents primarily affecting the gastro-intestinal system	0.269	0.731	0.000
Y50 Central nervous system stimulants, not elsewhere classified	0.269	0.731	0.000
Y49 Psychotropic drugs, not elsewhere classified	0.269	0.731	0.000
Y48 Anaesthetics and therapeutic gases	0.269	0.731	0.000
Y47 Sedatives, hypnotics and antianxiety drugs	0.269	0.731	0.000
Y46 Antiepileptics and anti-Parkinsonism drugs	0.269	0.731	0.000
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified	0.268	0.732	0.000
S00.8 Superficial injury of other parts of head	0.268	0.732	0.000
C82.7 Other types of follicular non-Hodgkin's lymphoma	0.267	0.732	0.000
C82.6 Cutaneous follicle centre lymphoma	0.267	0.732	0.000
C82.5 Diffuse follicle centre lymphoma	0.267	0.732	0.000
C82.4 Follicular lymphoma grade IIIb	0.267	0.732	0.000
C82.3 Follicular lymphoma grade IIIa	0.267	0.732	0.000
C82.2 Large cell, follicular	0.267	0.732	0.000
C82.1 Mixed small cleaved and large cell, follicular	0.267	0.732	0.000
C82.0 Small cleaved cell, follicular	0.267	0.732	0.000
Chapter XXII Codes for special purposes	0.267	0.733	0.000
S86 Injury of muscle and tendon at lower leg level	0.266	0.734	0.000
J18.2 Hypostatic pneumonia, unspecified	0.264	0.735	0.000
S05 Injury of eye and orbit	0.264	0.736	0.000
T17.2 Foreign body in pharynx	0.264	0.736	0.000
C10 Malignant neoplasm of oropharynx	0.264	0.736	0.000
D23.9 Skin, unspecified	0.264	0.736	0.000
D23.0 Skin of lip	0.264	0.736	0.000
T65 Toxic effect of other and unspecified substances	0.263	0.736	0.000
T62 Toxic effect of other noxious substances eaten as food	0.263	0.736	0.000
T61 Toxic effect of noxious substances eaten as seafood	0.263	0.736	0.000
T60 Toxic effect of pesticides	0.263	0.736	0.000
T59 Toxic effect of other gases, fumes and vapours	0.263	0.736	0.000
T57 Toxic effect of other inorganic substances	0.263	0.736	0.000
T56 Toxic effect of metals	0.263	0.736	0.000
T54 Toxic effect of corrosive substances	0.263	0.736	0.000
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone	0.263	0.736	0.000
T52 Toxic effect of organic solvents	0.263	0.736	0.000
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants	0.263	0.736	0.000
T58 Toxic effect of carbon monoxide	0.263	0.736	0.000
T55 Toxic effect of soaps and detergents	0.263	0.736	0.000
L40-L45 Papulosquamous disorders	0.263	0.737	0.000
J04 Acute laryngitis and tracheitis	0.263	0.737	0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum	0.262	0.738	0.000
D19 Benign neoplasm of mesothelial tissue	0.262	0.738	0.000
D16 Benign neoplasm of bone and articular cartilage	0.262	0.738	0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs	0.262	0.738	0.000
D32.0 Cerebral meninges	0.262	0.738	0.000
D47.3 Essential (haemorrhagic) thrombocythaemia	0.262	0.738	0.000
W07 Fall involving chair	0.262	0.738	0.000
D04.7 Skin of lower limb, including hip	0.262	0.738	0.000
S08 Traumatic amputation of part of head	0.261	0.739	0.000
S07 Crushing injury of head	0.261	0.739	0.000
S04 Injury of cranial nerves	0.261	0.739	0.000
S03 Dislocation, sprain and strain of joints and ligaments of head	0.261	0.739	0.000
Y79 Orthopaedic devices associated with adverse incidents	0.260	0.740	0.000
H90-H95 Other disorders of ear	0.260	0.740	0.000
D28 Benign neoplasm of other and unspecified female genital organs	0.260	0.740	0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.260	0.740	0.000
D13 Benign neoplasm of other and ill-defined parts of digestive system	0.260	0.740	0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.259	0.741	0.000
Y45.0 Opioids and related analgesics	0.259	0.741	0.000
D11 Benign neoplasm of major salivary glands	0.259	0.741	0.000
Y45.1 Salicylates	0.259	0.741	0.000
D31.0 Conjunctiva	0.258	0.742	0.000
J34 Other disorders of nose and nasal sinuses	0.258	0.742	0.000
X78 Intentional self-harm by sharp object	0.258	0.742	0.000
D02 Carcinoma in situ of middle ear and respiratory system	0.258	0.742	0.000
D01 Carcinoma in situ of other and unspecified digestive organs	0.258	0.742	0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach	0.258	0.742	0.000
C45.0 Mesothelioma of pleura	0.257	0.743	0.000
D47.4 Osteomyelofibrosis	0.257	0.743	0.000
Q50-Q56 Congenital malformations of genital organs	0.257	0.743	0.000
D31.3 Choroid	0.257	0.743	0.000
S32.4 Fracture of acetabulum	0.257	0.743	0.000
C48 Malignant neoplasm of retroperitoneum and peritoneum	0.256	0.744	0.000
C47 Malignant neoplasm of peripheral nerves and autonomic nervous system	0.256	0.744	0.000
C46 Kaposi's sarcoma	0.256	0.744	0.000
S89 Other and unspecified injuries of lower leg	0.256	0.744	0.000
B00 Herpesviral [herpes simplex] infections	0.256	0.744	0.000
Y42.7 Androgens and anabolic congeners	0.256	0.744	0.000
D22 Melanocytic naevi	0.255	0.745	0.000
C79 Secondary malignant neoplasm of other sites	0.255	0.745	0.000
J99 Respiratory disorders in diseases classified elsewhere	0.255	0.745	0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.255	0.745	0.000
H71 Cholesteatoma of middle ear	0.255	0.745	0.000
L80-L99 Other disorders of the skin and subcutaneous tissue	0.255	0.745	0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis	0.255	0.745	0.000
H70 Mastoiditis and related conditions	0.254	0.746	0.000
A80-A89 Viral infections of the central nervous system	0.254	0.746	0.000
H74 Other disorders of middle ear and mastoid	0.254	0.746	0.000
S80.8 Other superficial injuries of lower leg	0.254	0.746	0.000
J94 Other pleural conditions	0.253	0.746	0.000
D04.6 Skin of upper limb, including shoulder	0.253	0.746	0.000
D32.9 Meninges, unspecified	0.252	0.748	0.000
O43 Placental disorders	0.252	0.748	0.000
S81.0 Open wound of knee	0.252	0.748	0.000
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified	0.252	0.748	0.000
Y45.5 4-Aminophenol derivatives	0.252	0.748	0.000
Y45.4 Antirheumatics	0.252	0.748	0.000
O20.8 Other haemorrhage in early pregnancy	0.252	0.748	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.252	0.748	0.000
C13 Malignant neoplasm of hypopharynx	0.251	0.749	0.000
C11 Malignant neoplasm of nasopharynx	0.251	0.749	0.000
C08 Malignant neoplasm of other and unspecified major salivary glands	0.251	0.749	0.000
C06 Malignant neoplasm of other and unspecified parts of mouth	0.251	0.749	0.000
C05 Malignant neoplasm of palate	0.251	0.749	0.000
C03 Malignant neoplasm of gum	0.251	0.749	0.000
C02 Malignant neoplasm of other and unspecified parts of tongue	0.251	0.749	0.000
C00 Malignant neoplasm of lip	0.251	0.749	0.000
C12 Malignant neoplasm of pyriform sinus	0.251	0.749	0.000
C07 Malignant neoplasm of parotid gland	0.251	0.749	0.000
O24.9 Diabetes mellitus in pregnancy, unspecified	0.250	0.750	0.000
O24.3 Pre-existing diabetes mellitus, unspecified	0.250	0.750	0.000
O24.2 Pre-existing malnutrition-related diabetes mellitus	0.250	0.750	0.000
O24.1 Pre-existing diabetes mellitus, noninsulin-dependent	0.250	0.750	0.000
H65.3 Chronic mucoid otitis media	0.250	0.750	0.000
S32.3 Fracture of ilium	0.250	0.750	0.000
V20-V29 Motorcycle rider injured in transport accident	0.250	0.750	0.000
Chapter V Mental and behavioural disorders	0.250	0.750	0.000
J70 Respiratory conditions due to other external agents	0.249	0.750	0.000
J68 Respiratory conditions due to inhalation of chemicals, gases, fumes and vapours	0.249	0.750	0.000
J66 Airway disease due to specific organic dust	0.249	0.750	0.000
J63 Pneumoconiosis due to other inorganic dusts	0.249	0.750	0.000
J62 Pneumoconiosis due to dust containing silica	0.249	0.750	0.000
J65 Pneumoconiosis associated with tuberculosis	0.249	0.750	0.000
J64 Unspecified pneumoconiosis	0.249	0.750	0.000
J60 Coalworker's pneumoconiosis	0.249	0.750	0.000
C44.0 Skin of lip	0.249	0.751	0.000
Y52.4 Angiotensin-converting-enzyme inhibitors	0.249	0.751	0.000
O23.4 Unspecified infection of urinary tract in pregnancy	0.249	0.751	0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.249	0.751	0.000
S37 Injury of urinary and pelvic organs	0.249	0.751	0.000
S36 Injury of intra-abdominal organs	0.249	0.751	0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.249	0.751	0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.249	0.751	0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.249	0.751	0.000
S31 Open wound of abdomen, lower back and pelvis	0.249	0.751	0.000
V10-V19 Pedal cyclist injured in transport accident	0.249	0.751	0.000
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified	0.249	0.751	0.000
Chapter XIV Diseases of the genitourinary system	0.249	0.751	0.000
T51.8 Other alcohols	0.248	0.751	0.000
T51.3 Fusel oil	0.248	0.751	0.000
T51.2 2-Propanol	0.248	0.751	0.000
T51.1 Methanol	0.248	0.751	0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.248	0.752	0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.248	0.752	0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.248	0.752	0.000
Q21 Congenital malformations of cardiac septa	0.248	0.752	0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.248	0.752	0.000
B49 Unspecified mycosis	0.248	0.752	0.000
O45 Premature separation of placenta [abruptio placentae]	0.248	0.752	0.000
O33 Maternal care for known or suspected disproportion	0.248	0.752	0.000
O31 Complications specific to multiple gestation	0.248	0.752	0.000
O40 Polyhydramnios	0.248	0.752	0.000
J18.0 Bronchopneumonia, unspecified	0.248	0.752	0.000
B07 Viral warts	0.247	0.752	0.000
Y43 Primarily systemic agents	0.247	0.753	0.000
D03.5 Melanoma in situ of trunk	0.247	0.753	0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.247	0.753	0.000
A07 Other protozoal intestinal diseases	0.247	0.753	0.000
A06 Amoebiasis	0.247	0.753	0.000
A05 Other bacterial foodborne intoxications	0.247	0.753	0.000
A03 Shigellosis	0.247	0.753	0.000
A01 Typhoid and paratyphoid fevers	0.247	0.753	0.000
A00 Cholera	0.247	0.753	0.000
S01.0 Open wound of scalp	0.247	0.753	0.000
C09.9 Tonsil, unspecified	0.246	0.754	0.000
A02 Other Salmonella infections	0.246	0.754	0.000
O47.1 False labour at or after 37 completed weeks of gestation	0.246	0.754	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.246	0.754	0.000
Q35-Q37 Cleft lip and cleft palate	0.246	0.754	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.246	0.754	0.000
Q00-Q07 Congenital malformations of the nervous system	0.246	0.754	0.000
O15 Eclampsia	0.246	0.754	0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.246	0.754	0.000
O11 Pre-existing hypertensive disorder with superimposed proteinuria	0.246	0.754	0.000
J02 Acute pharyngitis	0.246	0.754	0.000
C45.9 Mesothelioma, unspecified	0.245	0.754	0.000
O23.5 Infections of the genital tract in pregnancy	0.245	0.755	0.000
S42 Fracture of shoulder and upper arm	0.245	0.755	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.245	0.755	0.000
S32.50 Fracture of pubis (closed)	0.244	0.756	0.000
D23.3 Skin of other and unspecified parts of face	0.244	0.756	0.000
J98 Other respiratory disorders	0.244	0.756	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.244	0.756	0.000
O28.1 Abnormal biochemical finding on antenatal screening of mother	0.244	0.756	0.000
D18 Haemangioma and lymphangioma, any site	0.244	0.756	0.000
C91.0 Acute lymphoblastic leukaemia	0.243	0.757	0.000
H61.2 Impacted cerumen	0.243	0.757	0.000
O08 Complications following abortion and ectopic and molar pregnancy	0.243	0.757	0.000
O07 Failed attempted abortion	0.243	0.757	0.000
O06 Unspecified abortion	0.243	0.757	0.000
O05 Other abortion	0.243	0.757	0.000
O01 Hydatidiform mole	0.243	0.757	0.000
D34 Benign neoplasm of thyroid gland	0.243	0.757	0.000
X59 Exposure to unspecified factor	0.242	0.758	0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.242	0.758	0.000
J20-J22 Other acute lower respiratory infections	0.242	0.758	0.000
J95.8 Other postprocedural respiratory disorders	0.242	0.758	0.000
S01.7 Multiple open wounds of head	0.242	0.758	0.000
S01.4 Open wound of cheek and temporomandibular area	0.242	0.758	0.000
C43 Malignant melanoma of skin	0.242	0.758	0.000
S88 Traumatic amputation of lower leg	0.241	0.758	0.000
S87 Crushing injury of lower leg	0.241	0.758	0.000
S85 Injury of blood vessels at lower leg level	0.241	0.758	0.000
S84 Injury of nerves at lower leg level	0.241	0.758	0.000
O36 Maternal care for other known or suspected foetal problems	0.241	0.759	0.000
O44 Placenta praevia	0.241	0.759	0.000
O32.8 Maternal care for other malpresentation of foetus	0.241	0.759	0.000
Y44.9 Other and unspecified agents affecting blood constituents	0.241	0.759	0.000
Y44.7 Plasma substitutes	0.241	0.759	0.000
Y44.6 Natural blood and blood products	0.241	0.759	0.000
Y44.5 Thrombolytic drugs	0.241	0.759	0.000
Y44.4 Antithrombotic drugs [platelet-aggregation inhibitors]	0.241	0.759	0.000
Y44.3 Anticoagulant antagonists, vitamin K and other coagulants	0.241	0.759	0.000
Y44.1 Vitamin B12, folic acid and other anti-megaloblastic-anaemia preparations	0.241	0.759	0.000
Y44.0 Iron preparations and other anti-hypochromic-anaemia preparations	0.241	0.759	0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.241	0.759	0.000
S51 Open wound of forearm	0.240	0.759	0.000
J96 Respiratory failure, not elsewhere classified	0.240	0.760	0.000
W07.0 Home	0.240	0.760	0.000
C90.0 Multiple myeloma	0.240	0.760	0.000
D03.3 Melanoma in situ of other and unspecified parts of face	0.240	0.760	0.000
B35 Dermatophytosis	0.240	0.760	0.000
T17.9 Foreign body in respiratory tract, part unspecified	0.240	0.760	0.000
H65.4 Other chronic nonsuppurative otitis media	0.240	0.760	0.000
D25 Leiomyoma of uterus	0.240	0.760	0.000
D35 Benign neoplasm of other and unspecified endocrine glands	0.239	0.760	0.000
H61.9 Disorder of external ear, unspecified	0.239	0.760	0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.239	0.761	0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.239	0.761	0.000
A63 Other predominantly sexually transmitted diseases, not elsewhere classified	0.239	0.761	0.000
H69 Other disorders of Eustachian tube	0.239	0.761	0.000
L40 Psoriasis	0.238	0.762	0.000
A30-A49 Other bacterial diseases	0.238	0.762	0.001
D47.9 Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified	0.238	0.762	0.000
D47.7 Other specified neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.238	0.762	0.000
D47.5 Chronic eosinophilic leukaemia [hypereosinophilic syndrome]	0.238	0.762	0.000
D47.0 Histiocytic and mast cell tumours of uncertain and unknown behaviour	0.238	0.762	0.000
S09 Other and unspecified injuries of head	0.238	0.762	0.000
C49.2 Connective and soft tissue of lower limb, including hip	0.238	0.762	0.000
D14.4 Respiratory system, unspecified	0.238	0.762	0.000
D14.3 Bronchus and lung	0.238	0.762	0.000
D14.2 Trachea	0.238	0.762	0.000
D14.1 Larynx	0.238	0.762	0.000
D07 Carcinoma in situ of other and unspecified genital organs	0.238	0.762	0.000
O20.9 Haemorrhage in early pregnancy, unspecified	0.238	0.762	0.000
O02 Other abnormal products of conception	0.237	0.763	0.000
S30 Superficial injury of abdomen, lower back and pelvis	0.237	0.763	0.000
X63 Intentional self-poisoning by and exposure to other drugs acting on the autonomic nervous system	0.237	0.763	0.000
T19 Foreign body in genito-urinary tract	0.237	0.763	0.000
T15 Foreign body on external eye	0.237	0.763	0.000
T16 Foreign body in ear	0.237	0.763	0.000
O48 Prolonged pregnancy	0.237	0.763	0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.237	0.763	0.000
O04.1 Incomplete, complicated by delayed or excessive haemorrhage	0.237	0.763	0.000
B17 Other acute viral hepatitis	0.236	0.763	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations