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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs111451951
log Bayes Factor = 15.0174
Chromosome 11   position 99,252,963  (GRCh37) Explore rs111451951 on Ensembl!
Variant rs111451951 is part of Cluster X0157

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter XX External causes of morbidity and mortality
1.000 0.000 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.999 0.001 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.999 0.001 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.999 0.001 0.000
E10-E14 Diabetes mellitus
0.998 0.002 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.997 0.003 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.995 0.005 0.000
E00-E07 Disorders of thyroid gland
0.994 0.006 0.000
O60-O75 Complications of labour and delivery
0.993 0.007 0.000
E10 Insulin-dependent diabetes mellitus
0.990 0.010 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.988 0.012 0.000
Chapter VII Diseases of the eye and adnexa
0.981 0.019 0.000
E03 Other hypothyroidism
0.981 0.019 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.981 0.019 0.000
S20-S29 Injuries to the thorax
0.976 0.024 0.000
E10.9 Without complications
0.976 0.024 0.000
E03.9 Hypothyroidism, unspecified
0.971 0.029 0.000
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid
0.969 0.031 0.000
L89 Decubitus ulcer
0.961 0.039 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.961 0.039 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.960 0.040 0.000
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified
0.960 0.040 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.960 0.040 0.000
H53-H54 Visual disturbances and blindness
0.954 0.046 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.953 0.047 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.951 0.049 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.947 0.053 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.929 0.071 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.929 0.071 0.000
L98.8 Other specified disorders of skin and subcutaneous tissue
0.926 0.074 0.000
E11 Non-insulin-dependent diabetes mellitus
0.925 0.075 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.922 0.078 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.922 0.078 0.000
H53 Visual disturbances
0.919 0.081 0.000
M20-M25 Other joint disorders
0.918 0.082 0.000
Y86 Sequelae of other accidents
0.918 0.082 0.000
O68.8 Labour and delivery complicated by other evidence of foetal stress
0.917 0.083 0.000
M20 Acquired deformities of fingers and toes
0.912 0.088 0.000
M20.4 Other hammer toe(s) (acquired)
0.904 0.096 0.000
T81 Complications of procedures, not elsewhere classified
0.902 0.098 0.000
L85 Other epidermal thickening
0.899 0.101 0.000
T93 Sequelae of injuries of lower limb
0.898 0.102 0.000
Y40 Systemic antibiotics
0.897 0.103 0.000
Chapter XXI Factors influencing health status and contact with health services
0.897 0.103 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.897 0.103 0.000
D80-D89 Certain disorders involving the immune mechanism
0.897 0.103 0.000
Y44 Agents primarily affecting blood constituents
0.894 0.106 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.893 0.107 0.000
L82 Seborrhoeic keratosis
0.892 0.108 0.000
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified
0.891 0.109 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.887 0.113 0.000
Chapter VI Diseases of the nervous system
0.887 0.113 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.884 0.116 0.000
O68.9 Labour and delivery complicated by foetal stress, unspecified
0.875 0.125 0.000
E11.3 With ophthalmic complications
0.874 0.126 0.000
M20.1 Hallux valgus (acquired)
0.874 0.126 0.000
H30-H36 Disorders of choroid and retina
0.872 0.128 0.000
D69 Purpura and other haemorrhagic conditions
0.870 0.130 0.000
E70-E90 Metabolic disorders
0.869 0.131 0.000
S22.4 Multiple fractures of ribs
0.867 0.133 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.866 0.134 0.000
Z53 Persons encountering health services for specifie procedures, not carried out
0.864 0.136 0.000
S00-S09 Injuries to the head
0.859 0.141 0.000
Z53.0 Procedure not carried out because of contraindication
0.859 0.141 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.857 0.143 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.857 0.143 0.000
E06 Thyroiditis
0.855 0.145 0.000
O85-O92 Complications predominantly related to the puerperium
0.853 0.147 0.000
Y42.0 Glucocorticoids and synthetic analogs
0.851 0.149 0.000
S10-S19 Injuries to the neck
0.849 0.151 0.000
Chapter IX Diseases of the circulatory system
0.846 0.154 0.000
E13 Other specified diabetes mellitus
0.845 0.155 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.841 0.159 0.000
Z41 Procedures for purposes other than remedying health state
0.840 0.159 0.000
L91 Hypertrophic disorders of skin
0.840 0.160 0.000
L89.0 Stage I decubitus ulcer and pressure area
0.840 0.160 0.000
S27 Injury of other and unspecified intrathoracic organs
0.839 0.161 0.000
L89.9 Decubitus ulcer and pressure area, unspecified
0.834 0.166 0.000
H40-H42 Glaucoma
0.832 0.168 0.000
M50-M54 Other dorsopathies
0.830 0.170 0.000
S20 Superficial injury of thorax
0.829 0.171 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.828 0.172 0.000
D89.2 Hypergammaglobulinaemia, unspecified
0.828 0.172 0.000
S22.40 Multiple fractures of ribs (closed)
0.827 0.173 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.826 0.174 0.000
D50-D53 Nutritional anaemias
0.826 0.174 0.000
T83.0 Mechanical complication of urinary (indwelling) catheter
0.822 0.178 0.000
O66 Other obstructed labour
0.822 0.178 0.000
Q50-Q56 Congenital malformations of genital organs
0.821 0.179 0.000
Y44.2 Anticoagulants
0.821 0.179 0.000
E10.5 With peripheral circulatory complications
0.820 0.180 0.000
E87.5 Hyperkalaemia
0.820 0.180 0.000
O00-O08 Pregnancy with abortive outcome
0.820 0.180 0.000
L89.1 Stage II decubitus ulcer
0.819 0.181 0.000
L81 Other disorders of pigmentation
0.818 0.182 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.818 0.182 0.000
Y42.7 Androgens and anabolic congeners
0.818 0.182 0.000
L20-L30 Dermatitis and eczema
0.814 0.186 0.000
H53.8 Other visual disturbances
0.813 0.187 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.812 0.188 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.812 0.188 0.000
Z49 Care involving dialysis
0.810 0.190 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.808 0.192 0.000
L85.9 Epidermal thickening, unspecified
0.806 0.194 0.000
D69.6 Thrombocytopenia, unspecified
0.806 0.194 0.000
S02 Fracture of skull and facial bones
0.805 0.195 0.000
Z41.1 Other plastic surgery for unacceptable cosmetic appearance
0.803 0.197 0.000
H54 Blindness and low vision
0.802 0.198 0.000
Chapter VIII Diseases of the ear and mastoid process
0.802 0.198 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.802 0.198 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.801 0.199 0.000
T87 Complications peculiar to reattachment and amputation
0.801 0.199 0.000
L83 Acanthosis nigricans
0.799 0.201 0.000
H53.4 Visual field defects
0.799 0.201 0.000
E05.9 Thyrotoxicosis, unspecified
0.798 0.202 0.000
S90-S99 Injuries to the ankle and foot
0.796 0.204 0.000
Y57 Other and unspecified drugs and medicaments
0.796 0.204 0.000
Z40 Prophylactic surgery
0.795 0.205 0.000
T93.3 Sequelae of dislocation, sprain and strain of lower limb
0.795 0.205 0.000
M86-M90 Other osteopathies
0.794 0.206 0.000
H36 Retinal disorders in diseases classified elsewhere
0.793 0.207 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.792 0.208 0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria
0.792 0.208 0.000
H10-H13 Disorders of conjunctiva
0.790 0.209 0.000
E10.8 With unspecified complications
0.789 0.211 0.000
W50-W64 Exposure to animate mechanical forces
0.786 0.214 0.000
I95 Hypotension
0.783 0.217 0.000
H53.2 Diplopia
0.782 0.218 0.000
X10-X19 Contact with heat and hot substances
0.779 0.221 0.000
Y42.5 Other oestrogens and progestogens
0.779 0.221 0.000
T92 Sequelae of injuries of upper limb
0.778 0.222 0.000
Q60-Q64 Congenital malformations of the urinary system
0.777 0.223 0.000
D55-D59 Haemolytic anaemias
0.777 0.223 0.000
Y40.9 Systemic antibiotic, unspecified
0.774 0.226 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.773 0.227 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.773 0.227 0.000
Y95 Nosocomial condition
0.773 0.227 0.000
L50-L54 Urticaria and erythema
0.772 0.228 0.000
E50-E64 Other nutritional deficiencies
0.772 0.228 0.000
S70-S79 Injuries to the hip and thigh
0.771 0.229 0.000
E40-E46 Malnutrition
0.771 0.229 0.000
I95.9 Hypotension, unspecified
0.770 0.230 0.000
Z48 Other surgical follow-up care
0.767 0.233 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.766 0.234 0.000
S22.3 Fracture of rib
0.765 0.235 0.000
E10.3 With ophthalmic complications
0.762 0.238 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.762 0.238 0.000
Z42 Follow-up care involving plastic surgery
0.761 0.239 0.000
T93.2 Sequelae of other fractures of lower limb
0.761 0.239 0.000
L98.4 Chronic ulcer of skin, not elsewhere classified
0.760 0.240 0.000
S40-S49 Injuries to the shoulder and upper arm
0.760 0.240 0.000
Y40.1 Cefalosporins and other -lactam antibiotics
0.758 0.242 0.000
H35 Other retinal disorders
0.757 0.243 0.000
L98.0 Pyogenic granuloma
0.757 0.243 0.000
M45-M49 Spondylopathies
0.757 0.243 0.000
Y41.8 Other specified systemic anti-infectives and antiparasitics
0.757 0.243 0.000
Y54.5 Other diuretics
0.756 0.243 0.000
I05-I09 Chronic rheumatic heart diseases
0.756 0.244 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.755 0.245 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.755 0.245 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.755 0.245 0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified
0.755 0.245 0.000
L93 Lupus erythematosus
0.754 0.246 0.000
T91 Sequelae of injuries of neck and trunk
0.754 0.246 0.000
M24 Other specific joint derangements
0.752 0.248 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.752 0.248 0.000
T83.1 Mechanical complication of other urinary devices and implants
0.747 0.253 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.746 0.254 0.000
M40-M43 Deforming dorsopathies
0.745 0.255 0.000
T85.4 Mechanical complication of breast prosthesis and implant
0.745 0.255 0.000
O68.1 Labour and delivery complicated by meconium in amniotic fluid
0.743 0.257 0.000
Z47 Other orthopaedic follow-up care
0.743 0.257 0.000
E10.2 With renal complications
0.741 0.259 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.741 0.259 0.000
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt
0.739 0.261 0.000
E11.1 With ketoacidosis
0.738 0.262 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.738 0.262 0.000
H36.0 Diabetic retinopathy
0.737 0.263 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.736 0.264 0.000
O63 Long labour
0.735 0.265 0.000
E13.9 Without complications
0.735 0.265 0.000
V40-V49 Car occupant injured in transport accident
0.735 0.265 0.000
S06 Intracranial injury
0.735 0.265 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.734 0.266 0.000
Y85 Sequelae of transport accidents
0.734 0.266 0.000
X60-X84 Intentional self-harm
0.733 0.267 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.732 0.268 0.000
E11.8 With unspecified complications
0.730 0.269 0.000
Z49.1 Extracorporeal dialysis
0.727 0.273 0.000
M21 Other acquired deformities of limbs
0.726 0.274 0.000
D69.9 Haemorrhagic condition, unspecified
0.725 0.275 0.000
H40 Glaucoma
0.725 0.275 0.000
Z40.0 Prophylactic surgery for risk-factors related to malignant neoplasms
0.725 0.275 0.000
H53.1 Subjective visual disturbances
0.724 0.276 0.000
L91.8 Other hypertrophic disorders of skin
0.724 0.276 0.000
E87.2 Acidosis
0.722 0.278 0.000
O70 Perineal laceration during delivery
0.722 0.278 0.000
E06.3 Autoimmune thyroiditis
0.722 0.278 0.000
T93.1 Sequelae of fracture of femur
0.721 0.279 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.721 0.279 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.720 0.280 0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system
0.719 0.281 0.000
O62 Abnormalities of forces of labour
0.719 0.281 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.719 0.281 0.000
M54 Dorsalgia
0.718 0.282 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.717 0.283 0.000
X20-X29 Contact with venomous animals and plants
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
E14 Unspecified diabetes mellitus
0.717 0.283 0.000
Y35-Y36 Legal intervention and operations of war
0.717 0.283 0.000
Y10-Y34 Event of undetermined intent
0.717 0.283 0.000
Y00-Y09 Assault
0.717 0.283 0.000
X85-X99 Assault
0.717 0.283 0.000
X30-X39 Exposure to forces of nature
0.717 0.283 0.000
X00-X09 Exposure to smoke, fire and flames
0.717 0.283 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.717 0.283 0.000
W75-W84 Other accidental threats to breathing
0.717 0.283 0.000
W65-W74 Accidental drowning and submersion
0.717 0.283 0.000
V98-V99 Other and unspecified transport accidents
0.717 0.283 0.000
V95-V97 Air and space transport accidents
0.717 0.283 0.000
V90-V94 Water transport accidents
0.717 0.283 0.000
V70-V79 Bus occupant injured in transport accident
0.717 0.283 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.717 0.283 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.717 0.283 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.717 0.283 0.000
V01-V09 Pedestrian injured in transport accident
0.717 0.283 0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.717 0.283 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.717 0.283 0.000
L94 Other localised connective tissue disorders
0.717 0.283 0.000
L87 Transepidermal elimination disorders
0.717 0.283 0.000
L88 Pyoderma gangrenosum
0.717 0.283 0.000
L86 Keratoderma in diseases classified elsewhere
0.717 0.283 0.000
L80 Vitiligo
0.717 0.283 0.000
L10-L14 Bullous disorders
0.716 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.716 0.284 0.000
M33 Dermatopolymyositis
0.716 0.284 0.000
Y59 Other and unspecified vaccines and biological substances
0.715 0.285 0.000
Y58 Bacterial vaccines
0.715 0.285 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.715 0.285 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.715 0.285 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.715 0.285 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.715 0.285 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.715 0.285 0.000
Y48 Anaesthetics and therapeutic gases
0.715 0.285 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.715 0.285 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.715 0.285 0.000
M60-M63 Disorders of muscles
0.714 0.286 0.000
X50-X57 Overexertion, travel and privation
0.714 0.286 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.713 0.287 0.000
E00 Congenital iodine-deficiency syndrome
0.713 0.287 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.713 0.287 0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes
0.713 0.287 0.000
O74 Complications of anaesthesia during labour and delivery
0.712 0.288 0.000
O71 Other obstetric trauma
0.712 0.288 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.712 0.288 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.712 0.288 0.000
O60 Preterm delivery
0.712 0.288 0.000
L89.2 Stage III decubitus ulcer
0.712 0.288 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.711 0.289 0.000
D68 Other coagulation defects
0.711 0.289 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.710 0.290 0.000
E10.7 With multiple complications
0.710 0.290 0.000
E10.6 With other specified complications
0.710 0.290 0.000
E10.0 With coma
0.710 0.290 0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments
0.709 0.291 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.709 0.291 0.000
O68.3 Labour and delivery complicated by biochemical evidence of foetal stress
0.708 0.292 0.000
T80.8 Other complications following infusion, transfusion and therapeutic injection
0.708 0.292 0.000
O36 Maternal care for other known or suspected foetal problems
0.708 0.292 0.000
T98 Sequelae of other and unspecified effects of external causes
0.707 0.293 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.707 0.293 0.000
O87 Venous complications in the puerperium
0.707 0.293 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.706 0.294 0.000
E88 Other metabolic disorders
0.706 0.294 0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts
0.705 0.295 0.000
Q80-Q89 Other congenital malformations
0.705 0.295 0.000
Z48.9 Surgical follow-up care, unspecified
0.705 0.295 0.000
V20-V29 Motorcycle rider injured in transport accident
0.704 0.295 0.000
S02.0 Fracture of vault of skull
0.704 0.296 0.000
E73 Lactose intolerance
0.703 0.296 0.000
E03.8 Other specified hypothyroidism
0.703 0.297 0.000
E03.5 Myxoedema coma
0.703 0.297 0.000
E03.4 Atrophy of thyroid (acquired)
0.703 0.297 0.000
E03.3 Postinfectious hypothyroidism
0.703 0.297 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.703 0.297 0.000
E03.1 Congenital hypothyroidism without goitre
0.703 0.297 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.703 0.297 0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension
0.702 0.298 0.000
L85.8 Other specified epidermal thickening
0.702 0.298 0.000
S20.8 Superficial injuries of other and unspecified parts of thorax
0.700 0.300 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.700 0.300 0.000
S26 Injury of heart
0.700 0.300 0.000
S25 Injury of blood vessels of thorax
0.700 0.300 0.000
S24 Injury of nerves and spinal cord at thorax level
0.700 0.300 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.700 0.300 0.000
S21 Open wound of thorax
0.700 0.300 0.000
Y91 Evidence of alcohol involvement determined by level of intoxication
0.699 0.301 0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts
0.699 0.301 0.000
T86 Failure and rejection of transplanted organs and tissues
0.698 0.301 0.000
M80-M85 Disorders of bone density and structure
0.698 0.302 0.000
E10.4 With neurological complications
0.697 0.303 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.696 0.304 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.695 0.305 0.000
S02.1 Fracture of base of skull
0.695 0.305 0.000
T79-T79 Certain early complications of trauma
0.694 0.306 0.000
G00 Bacterial meningitis, not elsewhere classified
0.692 0.308 0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure
0.692 0.308 0.000
M20.0 Deformity of finger(s)
0.691 0.309 0.000
Y52 Agents primarily affecting the cardiovascular system
0.691 0.309 0.000
M48 Other spondylopathies
0.691 0.309 0.000
Chapter XXII Codes for special purposes
0.690 0.310 0.000
L89.3 Stage IV decubitus ulcer
0.689 0.311 0.000
Y42.9 Other and unspecified hormone antagonists
0.688 0.311 0.000
Y42.4 Oral contraceptives
0.688 0.311 0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.688 0.311 0.000
Y42.2 Antithyroid drugs
0.688 0.311 0.000
Y42.1 Thyroid hormones and substitutes
0.688 0.311 0.000
L98.7 Excessive and redundant skin and subcutaneous tissue
0.688 0.311 0.000
L98.6 Other infiltrative disorders of skin and subcutaneous tissue
0.688 0.311 0.000
L98.5 Mucinosis of skin
0.688 0.311 0.000
L98.3 Eosinophilic cellulitis [Wells]
0.688 0.311 0.000
L98.2 Febrile neutrophilic dermatosis [Sweet]
0.688 0.311 0.000
L98.1 Factitial dermatitis
0.688 0.311 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.688 0.311 0.000
T95 Sequelae of burns, corrosions and frostbite
0.688 0.312 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.688 0.312 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.688 0.312 0.000
O85 Puerperal sepsis
0.688 0.312 0.000
E16 Other disorders of pancreatic internal secretion
0.688 0.312 0.000
S27.0 Traumatic pneumothorax
0.687 0.313 0.000
L27 Dermatitis due to substances taken internally
0.687 0.313 0.000
S05 Injury of eye and orbit
0.685 0.315 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.684 0.316 0.000
Y89 Sequelae of other external causes
0.683 0.317 0.000
Y87 Sequelae of intentional self-harm, assault and events of undetermined intent
0.683 0.317 0.000
M34 Systemic sclerosis
0.683 0.317 0.000
Q00-Q07 Congenital malformations of the nervous system
0.683 0.317 0.000
H53.9 Visual disturbance, unspecified
0.682 0.318 0.000
M00-M03 Infectious arthropathies
0.682 0.318 0.000
I10-I15 Hypertensive diseases
0.680 0.320 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.679 0.321 0.000
Q35-Q37 Cleft lip and cleft palate
0.679 0.321 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.679 0.321 0.000
O61 Failed induction of labour
0.678 0.322 0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care
0.678 0.322 0.000
D69.0 Allergic purpura
0.678 0.322 0.000
D52 Folate deficiency anaemia
0.677 0.323 0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts
0.676 0.324 0.000
T83.3 Mechanical complication of intra-uterine contraceptive device
0.675 0.325 0.000
T85.9 Unspecified complication of internal prosthetic device, implant and graft
0.673 0.327 0.000
E06.9 Thyroiditis, unspecified
0.673 0.327 0.000
E07 Other disorders of thyroid
0.672 0.328 0.000
H47 Other disorders of optic [2nd] nerve and visual pathways
0.670 0.329 0.000
S22.0 Fracture of thoracic vertebra
0.670 0.330 0.000
I60-I69 Cerebrovascular diseases
0.670 0.330 0.000
V80-V89 Other land transport accidents
0.670 0.330 0.000
Z52 Donors of organs and tissues
0.669 0.331 0.000
S11 Open wound of neck
0.669 0.331 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.669 0.331 0.000
S02.6 Fracture of mandible
0.668 0.332 0.000
E05.8 Other thyrotoxicosis
0.666 0.334 0.000
E05.5 Thyroid crisis or storm
0.666 0.334 0.000
E05.4 Thyrotoxicosis factitia
0.666 0.334 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.666 0.334 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.666 0.334 0.000
G70-G73 Diseases of myoneural junction and muscle
0.666 0.334 0.000
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft
0.666 0.334 0.000
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract
0.666 0.334 0.000
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract
0.666 0.334 0.000
T83.2 Mechanical complication of graft of urinary organ
0.666 0.334 0.000
H34 Retinal vascular occlusions
0.665 0.335 0.000
E11.6 With other specified complications
0.664 0.335 0.000
T90 Sequelae of injuries of head
0.663 0.337 0.000
T66-T78 Other and unspecified effects of external causes
0.663 0.337 0.000
E11.7 With multiple complications
0.663 0.337 0.000
E11.0 With coma
0.663 0.337 0.000
S10 Superficial injury of neck
0.663 0.337 0.000
T87.6 Other and unspecified complications of amputation stump
0.661 0.339 0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level
0.661 0.339 0.000
O66.5 Failed application of vacuum extractor and forceps, unspecified
0.661 0.339 0.000
S22.9 Fracture of bony thorax, part unspecified
0.661 0.339 0.000
S22.8 Fracture of other parts of bony thorax
0.661 0.339 0.000
S22.5 Flail chest
0.661 0.339 0.000
S22.1 Multiple fractures of thoracic spine
0.661 0.339 0.000
D67 Hereditary factor IX deficiency
0.661 0.339 0.000
D66 Hereditary factor VIII deficiency
0.661 0.339 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.661 0.339 0.000
H54.7 Unspecified visual loss
0.661 0.339 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.661 0.339 0.000
O70.0 First degree perineal laceration during delivery
0.659 0.341 0.000
H53.6 Night blindness
0.659 0.341 0.000
H53.5 Colour vision deficiencies
0.659 0.341 0.000
H53.3 Other disorders of binocular vision
0.659 0.341 0.000
H90-H95 Other disorders of ear
0.659 0.341 0.000
E87.6 Hypokalaemia
0.658 0.341 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.658 0.341 0.000
M32 Systemic lupus erythematosus
0.658 0.341 0.000
M30 Polyarteritis nodosa and related conditions
0.658 0.341 0.000
G06 Intracranial and intraspinal abscess and granuloma
0.657 0.343 0.000
Z44 Fitting and adjustment of external prosthetic device
0.657 0.343 0.000
D50 Iron deficiency anaemia
0.657 0.343 0.000
D60-D64 Aplastic and other anaemias
0.657 0.343 0.000
Y54.3 Benzothiadiazine derivatives
0.654 0.346 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.654 0.346 0.000
Z29 Need for other prophylactic measures
0.654 0.346 0.000
H11 Other disorders of conjunctiva
0.654 0.346 0.000
E11.2 With renal complications
0.654 0.346 0.000
Q61 Cystic kidney disease
0.653 0.346 0.000
H31 Other disorders of choroid
0.653 0.347 0.000
S22.30 Fracture of rib (closed)
0.653 0.347 0.000
L81.4 Other melanin hyperpigmentation
0.652 0.348 0.000
E53 Deficiency of other B group vitamins
0.651 0.349 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.650 0.349 0.000
Y40.8 Other systemic antibiotics
0.650 0.350 0.000
S27.2 Traumatic heamopneumothorax
0.650 0.350 0.000
M50 Cervical disk disorders
0.650 0.350 0.000
Z49.0 Preparatory care for dialysis
0.647 0.352 0.000
T81.6 Acute reaction to foreign substance accidentally left during a procedure
0.647 0.353 0.000
T81.1 Shock during or resulting from a procedure, not elsewhere classified
0.647 0.353 0.000
S27.1 Traumatic haemothorax
0.646 0.354 0.000
G90-G99 Other disorders of the nervous system
0.646 0.354 0.000
G30-G32 Other degenerative diseases of the nervous system
0.646 0.354 0.000
O03 Spontaneous abortion
0.646 0.354 0.000
L85.3 Xerosis cutis
0.644 0.355 0.000
L85.2 Keratosis punctata (palmaris et plantaris)
0.644 0.355 0.000
L85.1 Acquired keratosis [keratoderma] palmaris et plantaris
0.644 0.355 0.000
L85.0 Acquired ichthyosis
0.644 0.355 0.000
S50-S59 Injuries to the elbow and forearm
0.644 0.356 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.644 0.356 0.000
T93.9 Sequelae of unspecified injury of lower limb
0.644 0.356 0.000
T93.6 Sequelae of crushing injury and traumatic amputation of lower limb
0.644 0.356 0.000
T93.5 Sequelae of injury of muscle and tendon of lower limb
0.644 0.356 0.000
T93.4 Sequelae of injury of nerve of lower limb
0.644 0.356 0.000
T93.0 Sequelae of open wound of lower limb
0.644 0.356 0.000
O66.0 Obstructed labour due to shoulder dystocia
0.644 0.356 0.000
Y40.7 Antifungal antibiotics, systemically used
0.643 0.357 0.000
Y40.6 Rifamycins
0.643 0.357 0.000
Y40.5 Aminoglycosides
0.643 0.357 0.000
Y40.4 Tetracyclines
0.643 0.357 0.000
Y40.3 Macrolides
0.643 0.357 0.000
Y40.2 Chloramphenicol group
0.643 0.357 0.000
T85.2 Mechanical complication of intraocular lens
0.643 0.357 0.000
T85.1 Mechanical complication of implanted electronic stimulator of nervous system
0.643 0.357 0.000
D84 Other immunodeficiencies
0.643 0.357 0.000
D83 Common variable immunodeficiency
0.643 0.357 0.000
D82 Immunodeficiency associated with other major defects
0.643 0.357 0.000
D81 Combined immunodeficiencies
0.643 0.357 0.000
D80 Immunodeficiency with predominantly antibody defects
0.643 0.357 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.643 0.357 0.000
L40-L45 Papulosquamous disorders
0.642 0.358 0.000
H43-H45 Disorders of vitreous body and globe
0.642 0.358 0.000
Y44.9 Other and unspecified agents affecting blood constituents
0.641 0.359 0.000
Y44.7 Plasma substitutes
0.641 0.359 0.000
Y44.6 Natural blood and blood products
0.641 0.359 0.000
Y44.5 Thrombolytic drugs
0.641 0.359 0.000
Y44.4 Antithrombotic drugs [platelet-aggregation inhibitors]
0.641 0.359 0.000
Y44.3 Anticoagulant antagonists, vitamin K and other coagulants
0.641 0.359 0.000
Y44.1 Vitamin B12, folic acid and other anti-megaloblastic-anaemia preparations
0.641 0.359 0.000
Y44.0 Iron preparations and other anti-hypochromic-anaemia preparations
0.641 0.359 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.641 0.359 0.000
O64.8 Obstructed labour due to other malposition and malpresentation
0.641 0.359 0.000
E11.4 With neurological complications
0.641 0.359 0.000
O00 Ectopic pregnancy
0.640 0.360 0.000
O80-O84 Delivery
0.640 0.360 0.000
S29 Other and unspecified injuries of thorax
0.640 0.360 0.000
E11.5 With peripheral circulatory complications
0.640 0.360 0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria
0.640 0.360 0.000
M54.4 Lumbago with sciatica
0.640 0.360 0.000
O75.8 Other specified complications of labour and delivery
0.640 0.360 0.000
M20.5 Other deformities of toe(s) (acquired)
0.640 0.360 0.000
L84 Corns and callosities
0.639 0.360 0.000
L23 Allergic contact dermatitis
0.639 0.361 0.000
I95.0 Idiopathic hypotension
0.639 0.361 0.000
Z53.1 Procedure not carried out because of patient's decision for reasons of belief or group pressure
0.638 0.361 0.000
L81.9 Disorder of pigmentation, unspecified
0.638 0.362 0.000
S20.2 Contusion of thorax
0.637 0.363 0.000
T81.7 Vascular complications following a procedure, not elsewhere classified
0.637 0.363 0.000
O15 Eclampsia
0.636 0.364 0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium
0.636 0.364 0.000
O11 Pre-existing hypertensive disorder with superimposed proteinuria
0.636 0.364 0.000
Q54 Hypospadias
0.635 0.365 0.000
M90 Osteopathies in diseases classified elsewhere
0.635 0.365 0.000
S92 Fracture of foot, except ankle
0.635 0.365 0.000
Y90 Evidence of alcohol involvement determined by blood alcohol level
0.634 0.366 0.000
Y98 Lifestyle-related condition
0.634 0.366 0.000
Y97 Environmental-pollution-related condition
0.634 0.366 0.000
Y96 Work-related condition
0.634 0.366 0.000
T92.1 Sequelae of fracture of arm
0.633 0.366 0.000
M91-M94 Chondropathies
0.632 0.368 0.000
S02.00 Fracture of vault of skull (closed)
0.631 0.368 0.000
Y88 Sequelae of surgical and medical care as external cause
0.631 0.369 0.000
L53 Other erythematous conditions
0.631 0.369 0.000
S32 Fracture of lumbar spine and pelvis
0.631 0.369 0.000
Y65 Other misadventures during surgical and medical care
0.631 0.369 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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