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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs11150606
log Bayes Factor = 14.614
Chromosome 16   position 31,099,011  (GRCh37) Explore rs11150606 on Ensembl!
Variant rs11150606 is listed in the   GWAS Catalog   ⇪
Variant rs11150606 is part of Cluster X0047

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I30-I52 Other forms of heart disease
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.999 0.001 0.000
I50 Heart failure
0.999 0.001 0.000
Chapter XIV Diseases of the genitourinary system
0.994 0.006 0.000
I50.1 Left ventricular failure
0.992 0.008 0.000
Chapter XX External causes of morbidity and mortality
0.991 0.009 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.990 0.010 0.000
N17-N19 Renal failure
0.990 0.010 0.000
Chapter VII Diseases of the eye and adnexa
0.987 0.013 0.000
N18 Chronic renal failure
0.987 0.013 0.000
I10-I15 Hypertensive diseases
0.986 0.014 0.000
S00-S09 Injuries to the head
0.986 0.014 0.000
Chapter I Certain infectious and parasitic diseases
0.980 0.020 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.979 0.021 0.000
I10 Essential (primary) hypertension
0.973 0.027 0.000
I34 Nonrheumatic mitral valve disorders
0.962 0.038 0.000
I49 Other cardiac arrhythmias
0.958 0.042 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.957 0.043 0.000
N18.9 Chronic renal failure, unspecified
0.954 0.046 0.000
I51 Complications and ill-defined descriptions of heart disease
0.951 0.049 0.000
M05-M14 Inflammatory polyarthropathies
0.945 0.055 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.933 0.067 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.931 0.069 0.000
R30-R39 Symptoms and signs involving the urinary system
0.925 0.075 0.000
I34.0 Mitral (valve) insufficiency
0.924 0.076 0.000
H25-H28 Disorders of lens
0.921 0.079 0.000
I50.9 Heart failure, unspecified
0.911 0.089 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.911 0.089 0.000
R31 Unspecified haematuria
0.911 0.089 0.000
S02 Fracture of skull and facial bones
0.911 0.089 0.000
I46 Cardiac arrest
0.908 0.092 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.907 0.093 0.000
M50-M54 Other dorsopathies
0.906 0.094 0.000
I50.0 Congestive heart failure
0.906 0.094 0.000
I42 Cardiomyopathy
0.904 0.096 0.000
S01 Open wound of head
0.904 0.096 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.896 0.104 0.000
H25 Senile cataract
0.895 0.105 0.000
M06 Other rheumatoid arthritis
0.891 0.109 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.887 0.113 0.000
A30-A49 Other bacterial diseases
0.887 0.113 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.886 0.114 0.000
N18.4 Chronic kidney disease, stage 4
0.883 0.117 0.000
Chapter II Neoplasms
0.880 0.120 0.000
M45-M49 Spondylopathies
0.879 0.121 0.000
S20-S29 Injuries to the thorax
0.876 0.124 0.000
N00-N08 Glomerular diseases
0.869 0.131 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.866 0.134 0.000
L20-L30 Dermatitis and eczema
0.865 0.135 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.862 0.138 0.000
I51.9 Heart disease, unspecified
0.854 0.146 0.000
D10-D36 Benign neoplasms
0.853 0.147 0.000
M06.9 Rheumatoid arthritis, unspecified
0.853 0.147 0.000
I47 Paroxysmal tachycardia
0.851 0.149 0.000
H25.8 Other senile cataract
0.850 0.150 0.000
R21 Rash and other nonspecific skin eruption
0.850 0.150 0.000
H30-H36 Disorders of choroid and retina
0.846 0.154 0.000
B35-B49 Mycoses
0.845 0.155 0.000
N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.845 0.155 0.000
Y86 Sequelae of other accidents
0.844 0.156 0.000
I49.0 Ventricular fibrillation and flutter
0.837 0.163 0.000
R35 Polyuria
0.837 0.163 0.000
N18.3 Chronic kidney disease, stage 3
0.834 0.166 0.000
I51.7 Cardiomegaly
0.834 0.166 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.833 0.167 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.831 0.169 0.000
R33 Retention of urine
0.831 0.169 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.830 0.170 0.000
B95-B98 Bacterial, viral and other infectious agents
0.829 0.171 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.829 0.171 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.828 0.172 0.000
T66-T78 Other and unspecified effects of external causes
0.828 0.172 0.000
W20-W49 Exposure to inanimate mechanical forces
0.827 0.173 0.000
N17 Acute renal failure
0.823 0.177 0.000
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified
0.822 0.178 0.000
H25.1 Senile nuclear cataract
0.822 0.178 0.000
D22 Melanocytic naevi
0.821 0.179 0.000
M50 Cervical disk disorders
0.816 0.184 0.000
I05-I09 Chronic rheumatic heart diseases
0.812 0.188 0.000
I49.3 Ventricular premature depolarisation
0.810 0.190 0.000
D27 Benign neoplasm of ovary
0.810 0.190 0.000
Y43 Primarily systemic agents
0.810 0.190 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.809 0.191 0.000
Chapter X Diseases of the respiratory system
0.809 0.191 0.000
N83.2 Other and unspecified ovarian cysts
0.808 0.192 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.807 0.193 0.000
I38 Endocarditis, valve unspecified
0.807 0.193 0.000
N18.5 Chronic kidney disease, stage 5
0.806 0.194 0.000
S05 Injury of eye and orbit
0.805 0.195 0.000
M10 Gout
0.800 0.199 0.000
N25-N29 Other disorders of kidney and ureter
0.799 0.201 0.000
I44 Atrioventricular and left bundle-branch block
0.798 0.202 0.000
C64-C68 Malignant neoplasms of urinary tract
0.796 0.204 0.000
S06 Intracranial injury
0.796 0.204 0.000
S00 Superficial injury of head
0.794 0.206 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.792 0.208 0.000
A00-A09 Intestinal infectious diseases
0.792 0.208 0.000
L98.0 Pyogenic granuloma
0.791 0.209 0.000
S10-S19 Injuries to the neck
0.790 0.210 0.000
S01.2 Open wound of nose
0.790 0.210 0.000
I42.0 Dilated cardiomyopathy
0.789 0.211 0.000
I12 Hypertensive renal disease
0.788 0.212 0.000
I49.8 Other specified cardiac arrhythmias
0.786 0.214 0.000
A41 Other septicaemia
0.786 0.214 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.785 0.215 0.000
N18.0 End-stage renal disease
0.784 0.215 0.000
M48 Other spondylopathies
0.784 0.216 0.000
I45 Other conduction disorders
0.784 0.216 0.000
I46.0 Cardiac arrest with successful resuscitation
0.782 0.218 0.000
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt
0.782 0.218 0.000
T86 Failure and rejection of transplanted organs and tissues
0.777 0.223 0.000
N18.2 Chronic kidney disease, stage 2
0.777 0.223 0.000
M40-M43 Deforming dorsopathies
0.777 0.223 0.000
I60-I69 Cerebrovascular diseases
0.777 0.223 0.000
B15-B19 Viral hepatitis
0.773 0.227 0.000
I46.9 Cardiac arrest, unspecified
0.772 0.228 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.772 0.228 0.000
W00-W19 Falls
0.768 0.232 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.767 0.233 0.000
S02.1 Fracture of base of skull
0.767 0.233 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.766 0.234 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.766 0.234 0.000
H36 Retinal disorders in diseases classified elsewhere
0.765 0.235 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.764 0.236 0.000
N83.8 Other noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.764 0.236 0.000
I34.1 Mitral (valve) prolapse
0.763 0.237 0.000
H10-H13 Disorders of conjunctiva
0.762 0.237 0.000
M86-M90 Other osteopathies
0.762 0.238 0.000
E65-E68 Obesity and other hyperalimentation
0.762 0.238 0.000
T85.2 Mechanical complication of intraocular lens
0.761 0.239 0.000
I47.1 Supraventricular tachycardia
0.760 0.240 0.000
H47 Other disorders of optic [2nd] nerve and visual pathways
0.759 0.241 0.000
I49.9 Cardiac arrhythmia, unspecified
0.757 0.243 0.000
N90 Other noninflammatory disorders of vulva and perineum
0.755 0.245 0.000
T85.9 Unspecified complication of internal prosthetic device, implant and graft
0.754 0.246 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.752 0.248 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.751 0.249 0.000
M54 Dorsalgia
0.750 0.250 0.000
D22.6 Melanocytic naevi of upper limb, including shoulder
0.749 0.251 0.000
B37 Candidiasis
0.749 0.251 0.000
L89 Decubitus ulcer
0.748 0.252 0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts
0.746 0.254 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.745 0.255 0.000
D25 Leiomyoma of uterus
0.744 0.256 0.000
I42.9 Cardiomyopathy, unspecified
0.744 0.256 0.000
S90-S99 Injuries to the ankle and foot
0.744 0.256 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.741 0.259 0.000
Y52 Agents primarily affecting the cardiovascular system
0.741 0.259 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.741 0.259 0.000
M50.3 Other cervical disk degeneration
0.741 0.259 0.000
I49.1 Atrial premature depolarisation
0.740 0.260 0.000
N30-N39 Other diseases of urinary system
0.740 0.260 0.000
L84 Corns and callosities
0.739 0.261 0.000
I20-I25 Ischaemic heart diseases
0.738 0.262 0.000
S02.9 Fracture of skull and facial bones, part unspecified
0.737 0.263 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.736 0.264 0.000
Y83.4 Other reconstructive surgery
0.735 0.265 0.000
M65-M68 Disorders of synovium and tendon
0.730 0.270 0.000
E10-E14 Diabetes mellitus
0.730 0.270 0.000
N99-N99 Other disorders of the genitourinary system
0.728 0.272 0.000
S02.3 Fracture of orbital floor
0.727 0.273 0.000
I51.8 Other ill-defined heart diseases
0.727 0.273 0.000
M05 Seropositive rheumatoid arthritis
0.725 0.275 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.725 0.275 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.725 0.275 0.000
R23 Other skin changes
0.724 0.276 0.000
H55-H59 Other disorders of eye and adnexa
0.723 0.277 0.000
M80-M85 Disorders of bone density and structure
0.721 0.279 0.000
L30 Other dermatitis
0.720 0.280 0.000
S01.0 Open wound of scalp
0.719 0.281 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.719 0.281 0.000
C43 Malignant melanoma of skin
0.719 0.281 0.000
S02.4 Fracture of malar and maxillary bones
0.717 0.283 0.000
M48.0 Spinal stenosis
0.717 0.283 0.000
I52 Other heart disorders in diseases classified elsewhere
0.717 0.283 0.000
I48 Atrial fibrillation and flutter
0.717 0.283 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.717 0.283 0.000
I41 Myocarditis in diseases classified elsewhere
0.717 0.283 0.000
I40 Acute myocarditis
0.717 0.283 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.717 0.283 0.000
I37 Pulmonary valve disorders
0.717 0.283 0.000
I36 Nonrheumatic tricuspid valve disorders
0.717 0.283 0.000
I33 Acute and subacute endocarditis
0.717 0.283 0.000
I32 Pericarditis in diseases classified elsewhere
0.717 0.283 0.000
I30 Acute pericarditis
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
H05 Disorders of orbit
0.717 0.283 0.000
C51-C58 Malignant neoplasms of female genital organs
0.717 0.283 0.000
T79-T79 Certain early complications of trauma
0.716 0.283 0.000
T33-T35 Frostbite
0.716 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.716 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.716 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.716 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.716 0.283 0.000
S70-S79 Injuries to the hip and thigh
0.716 0.284 0.000
Y43.4 Immunosuppressive agents
0.716 0.284 0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts
0.715 0.285 0.000
N03 Chronic nephritic syndrome
0.714 0.286 0.000
I25 Chronic ischaemic heart disease
0.714 0.286 0.000
H53-H54 Visual disturbances and blindness
0.713 0.287 0.000
N85 Other noninflammatory disorders of uterus, except cervix
0.713 0.287 0.000
E66 Obesity
0.713 0.287 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.710 0.290 0.000
Y35-Y36 Legal intervention and operations of war
0.710 0.290 0.000
Y10-Y34 Event of undetermined intent
0.710 0.290 0.000
Y00-Y09 Assault
0.710 0.290 0.000
X85-X99 Assault
0.710 0.290 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.710 0.290 0.000
X50-X57 Overexertion, travel and privation
0.710 0.290 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.710 0.290 0.000
X30-X39 Exposure to forces of nature
0.710 0.290 0.000
X20-X29 Contact with venomous animals and plants
0.710 0.290 0.000
X10-X19 Contact with heat and hot substances
0.710 0.290 0.000
X00-X09 Exposure to smoke, fire and flames
0.710 0.290 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.710 0.290 0.000
W75-W84 Other accidental threats to breathing
0.710 0.290 0.000
W65-W74 Accidental drowning and submersion
0.710 0.290 0.000
W50-W64 Exposure to animate mechanical forces
0.710 0.290 0.000
V98-V99 Other and unspecified transport accidents
0.710 0.290 0.000
V95-V97 Air and space transport accidents
0.710 0.290 0.000
V90-V94 Water transport accidents
0.710 0.290 0.000
V80-V89 Other land transport accidents
0.710 0.290 0.000
V70-V79 Bus occupant injured in transport accident
0.710 0.290 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.710 0.290 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.710 0.290 0.000
V40-V49 Car occupant injured in transport accident
0.710 0.290 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.710 0.290 0.000
V20-V29 Motorcycle rider injured in transport accident
0.710 0.290 0.000
V01-V09 Pedestrian injured in transport accident
0.710 0.290 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.710 0.290 0.000
M91-M94 Chondropathies
0.710 0.290 0.000
M60-M63 Disorders of muscles
0.710 0.290 0.000
M00-M03 Infectious arthropathies
0.710 0.290 0.000
H18 Other disorders of cornea
0.708 0.292 0.000
N18.8 Other chronic renal failure
0.708 0.292 0.000
N18.1 Chronic kidney disease, stage 1
0.708 0.292 0.000
I15 Secondary hypertension
0.707 0.293 0.000
I13 Hypertensive heart and renal disease
0.707 0.293 0.000
I11 Hypertensive heart disease
0.707 0.293 0.000
H25.0 Senile incipient cataract
0.707 0.293 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.707 0.293 0.000
H36.0 Diabetic retinopathy
0.707 0.293 0.000
W25 Contact with sharp glass
0.707 0.293 0.000
S08 Traumatic amputation of part of head
0.707 0.293 0.000
S07 Crushing injury of head
0.707 0.293 0.000
S04 Injury of cranial nerves
0.707 0.293 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.707 0.293 0.000
S50-S59 Injuries to the elbow and forearm
0.707 0.293 0.000
Y40 Systemic antibiotics
0.706 0.294 0.000
T78 Adverse effects, not elsewhere classified
0.705 0.295 0.000
N32 Other disorders of bladder
0.705 0.295 0.000
A46 Erysipelas
0.705 0.295 0.000
J60-J70 Lung diseases due to external agents
0.703 0.297 0.000
N17.9 Acute renal failure, unspecified
0.703 0.297 0.000
N02 Recurrent and persistent haematuria
0.703 0.297 0.000
B99-B99 Other infectious diseases
0.702 0.298 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.702 0.298 0.000
B65-B83 Helminthiases
0.702 0.298 0.000
B50-B64 Protozoal diseases
0.702 0.298 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.702 0.298 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.702 0.298 0.000
A80-A89 Viral infections of the central nervous system
0.702 0.298 0.000
A75-A79 Rickettsioses
0.702 0.298 0.000
A70-A74 Other diseases caused by chlamydiae
0.702 0.298 0.000
A65-A69 Other spirochaetal diseases
0.702 0.298 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.702 0.298 0.000
A20-A28 Certain zoonotic bacterial diseases
0.702 0.298 0.000
A15-A19 Tuberculosis
0.702 0.298 0.000
T87 Complications peculiar to reattachment and amputation
0.702 0.298 0.000
Y83.1 Surgical operation with implant of artificial internal device
0.702 0.298 0.000
Chapter VIII Diseases of the ear and mastoid process
0.701 0.299 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.701 0.299 0.000
Chapter XXII Codes for special purposes
0.700 0.300 0.000
Chapter VI Diseases of the nervous system
0.699 0.301 0.000
S01.9 Open wound of head, part unspecified
0.698 0.302 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.698 0.302 0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts
0.697 0.302 0.000
M10.9 Gout, unspecified
0.697 0.303 0.000
L29 Pruritus
0.697 0.303 0.000
B25-B34 Other viral diseases
0.696 0.304 0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.695 0.305 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.695 0.305 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.694 0.306 0.000
S01.3 Open wound of ear
0.694 0.306 0.000
N89 Other noninflammatory disorders of vagina
0.694 0.306 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.693 0.307 0.000
X60-X84 Intentional self-harm
0.692 0.308 0.000
D25.2 Subserosal leiomyoma of uterus
0.691 0.309 0.000
L50-L54 Urticaria and erythema
0.691 0.309 0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.689 0.310 0.000
I34.8 Other nonrheumatic mitral valve disorders
0.689 0.310 0.000
I34.2 Nonrheumatic mitral (valve) stenosis
0.689 0.310 0.000
I49.2 Junctional premature depolarisation
0.686 0.313 0.000
L10-L14 Bullous disorders
0.686 0.313 0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]
0.686 0.314 0.000
N86 Erosion and ectropion of cervix uteri
0.686 0.314 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.684 0.316 0.000
L27 Dermatitis due to substances taken internally
0.684 0.316 0.000
M47 Spondylosis
0.684 0.316 0.000
H47.3 Other disorders of optic disk
0.683 0.317 0.000
I51.6 Cardiovascular disease, unspecified
0.682 0.318 0.000
I51.5 Myocardial degeneration
0.682 0.318 0.000
I51.4 Myocarditis, unspecified
0.682 0.318 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.682 0.318 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.682 0.318 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.682 0.318 0.000
I51.0 Cardiac septal defect, acquired
0.682 0.318 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.681 0.319 0.000
S01.1 Open wound of eyelid and periocular area
0.681 0.319 0.000
J30-J39 Other diseases of upper respiratory tract
0.680 0.320 0.000
H02 Other disorders of eyelid
0.680 0.320 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.679 0.321 0.000
E11 Non-insulin-dependent diabetes mellitus
0.679 0.321 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.679 0.321 0.000
D22.0 Melanocytic naevi of lip
0.679 0.321 0.000
J95-J99 Other diseases of the respiratory system
0.678 0.322 0.000
I35 Nonrheumatic aortic valve disorders
0.678 0.322 0.000
S00.1 Contusion of eyelid and periocular area
0.677 0.323 0.000
M14 Arthropathies in other diseases classified elsewhere
0.677 0.323 0.000
M12 Other specific arthropathies
0.677 0.323 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.677 0.323 0.000
M08 Juvenile arthritis
0.677 0.323 0.000
M07 Psoriatic and enteropathic arthropathies
0.677 0.323 0.000
D22.3 Melanocytic naevi of other and unspecified parts of face
0.677 0.323 0.000
M48.06 Spinal stenosis (Lumbar region)
0.677 0.323 0.000
N10-N16 Renal tubulo-interstitial diseases
0.676 0.323 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.676 0.324 0.000
E66.9 Obesity, unspecified
0.676 0.324 0.000
S05.1 Contusion of eyeball and orbital tissues
0.675 0.325 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.675 0.325 0.000
N87 Dysplasia of cervix uteri
0.675 0.325 0.000
D16 Benign neoplasm of bone and articular cartilage
0.674 0.326 0.000
M70-M79 Other soft tissue disorders
0.673 0.327 0.000
A41.5 Septicaemia due to other Gram-negative organisms
0.672 0.328 0.000
N83.9 Noninflammatory disorder of ovary, Fallopian tube and broad ligament, unspecified
0.672 0.328 0.000
A41.0 Septicaemia due to Staphylococcus aureus
0.671 0.329 0.000
I08 Multiple valve diseases
0.669 0.330 0.000
T85.1 Mechanical complication of implanted electronic stimulator of nervous system
0.669 0.331 0.000
T90 Sequelae of injuries of head
0.668 0.331 0.000
H46 Optic neuritis
0.668 0.332 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.668 0.332 0.000
I62 Other nontraumatic intracranial haemorrhage
0.667 0.333 0.000
M50.1 Cervical disk disorder with radiculopathy
0.667 0.333 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.666 0.334 0.000
S00.0 Superficial injury of scalp
0.666 0.334 0.000
I49.5 Sick sinus syndrome
0.665 0.335 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.665 0.335 0.000
I44.7 Left bundle-branch block, unspecified
0.665 0.335 0.000
M54.9 Dorsalgia, unspecified
0.665 0.335 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.664 0.336 0.000
Chapter XXI Factors influencing health status and contact with health services
0.664 0.336 0.000
S02.10 Fracture of base of skull (closed)
0.664 0.336 0.000
D23 Other benign neoplasms of skin
0.664 0.336 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.664 0.336 0.000
I44.1 Atrioventricular block, second degree
0.663 0.337 0.000
R36 Urethral discharge
0.663 0.337 0.000
R34 Anuria and oliguria
0.663 0.337 0.000
S29 Other and unspecified injuries of thorax
0.663 0.337 0.000
C67 Malignant neoplasm of bladder
0.663 0.337 0.000
S40-S49 Injuries to the shoulder and upper arm
0.663 0.337 0.000
D35 Benign neoplasm of other and unspecified endocrine glands
0.662 0.338 0.000
L82 Seborrhoeic keratosis
0.661 0.339 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.660 0.339 0.000
H28 Cataract and other disorders of lens in diseases classified elsewhere
0.660 0.340 0.000
H27 Other disorders of lens
0.660 0.340 0.000
I42.2 Other hypertrophic cardiomyopathy
0.660 0.340 0.000
Y88 Sequelae of surgical and medical care as external cause
0.660 0.340 0.000
T85.4 Mechanical complication of breast prosthesis and implant
0.659 0.341 0.000
C43.7 Malignant melanoma of lower limb, including hip
0.659 0.341 0.000
N28 Other disorders of kidney and ureter, not elsewhere classified
0.658 0.341 0.000
A49 Bacterial infection of unspecified site
0.658 0.342 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.658 0.342 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.657 0.342 0.000
S80-S89 Injuries to the knee and lower leg
0.657 0.343 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.657 0.343 0.000
L85 Other epidermal thickening
0.656 0.344 0.000
H35 Other retinal disorders
0.655 0.345 0.000
S22.0 Fracture of thoracic vertebra
0.654 0.346 0.000
I45.5 Other specified heart block
0.654 0.346 0.000
S02.6 Fracture of mandible
0.654 0.346 0.000
Y59 Other and unspecified vaccines and biological substances
0.653 0.347 0.000
Y58 Bacterial vaccines
0.653 0.347 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.653 0.347 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.653 0.347 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.653 0.347 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.653 0.347 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.653 0.347 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.653 0.347 0.000
Y48 Anaesthetics and therapeutic gases
0.653 0.347 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.653 0.347 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.653 0.347 0.000
Y44 Agents primarily affecting blood constituents
0.653 0.347 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.653 0.347 0.000
S02.8 Fractures of other skull and facial bones
0.653 0.347 0.000
S02.7 Multiple fractures involving skull and facial bones
0.653 0.347 0.000
S02.5 Fracture of tooth
0.653 0.347 0.000
S02.0 Fracture of vault of skull
0.653 0.347 0.000
Y83.8 Other surgical procedures
0.653 0.347 0.000
H02.4 Ptosis of eyelid
0.652 0.348 0.000
T92 Sequelae of injuries of upper limb
0.651 0.348 0.000
M11 Other crystal arthropathies
0.651 0.349 0.000
S01.5 Open wound of lip and oral cavity
0.651 0.349 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.651 0.349 0.000
I46.1 Sudden cardiac death, so described
0.651 0.349 0.000
Y89 Sequelae of other external causes
0.650 0.350 0.000
Y87 Sequelae of intentional self-harm, assault and events of undetermined intent
0.650 0.350 0.000
Y85 Sequelae of transport accidents
0.650 0.350 0.000
M53 Other dorsopathies, not elsewhere classified
0.650 0.350 0.000
D13 Benign neoplasm of other and ill-defined parts of digestive system
0.649 0.351 0.000
I42.8 Other cardiomyopathies
0.648 0.352 0.000
I42.7 Cardiomyopathy due to drugs and other external agents
0.648 0.352 0.000
I42.6 Alcoholic cardiomyopathy
0.648 0.352 0.000
I42.5 Other restrictive cardiomyopathy
0.648 0.352 0.000
I42.4 Endocardial fibroelastosis
0.648 0.352 0.000
I42.3 Endomyocardial (eosinophilic) disease
0.648 0.352 0.000
I42.1 Obstructive hypertrophic cardiomyopathy
0.648 0.352 0.000
S01.7 Multiple open wounds of head
0.648 0.352 0.000
S01.4 Open wound of cheek and temporomandibular area
0.648 0.352 0.000
D22.2 Melanocytic naevi of ear and external auricular canal
0.648 0.352 0.000
N32.8 Other specified disorders of bladder
0.647 0.353 0.000
S27 Injury of other and unspecified intrathoracic organs
0.647 0.353 0.000
D26 Other benign neoplasms of uterus
0.647 0.353 0.000
E00-E07 Disorders of thyroid gland
0.646 0.354 0.000
C43.5 Malignant melanoma of trunk
0.646 0.354 0.000
L28 Lichen simplex chronicus and prurigo
0.646 0.354 0.000
B91 Sequelae of poliomyelitis
0.645 0.354 0.000
Y57 Other and unspecified drugs and medicaments
0.645 0.355 0.000
I12.9 Hypertensive renal disease without renal failure
0.645 0.355 0.000
I49.4 Other and unspecified premature depolarisation
0.645 0.355 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.645 0.355 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.645 0.355 0.000
N76 Other inflammation of vagina and vulva
0.644 0.356 0.000
S02.2 Fracture of nasal bones
0.644 0.356 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.643 0.357 0.000
V10-V19 Pedal cyclist injured in transport accident
0.642 0.358 0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.642 0.358 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.642 0.358 0.000
L94 Other localised connective tissue disorders
0.642 0.358 0.000
L93 Lupus erythematosus
0.642 0.358 0.000
L87 Transepidermal elimination disorders
0.642 0.358 0.000
L88 Pyoderma gangrenosum
0.642 0.358 0.000
L86 Keratoderma in diseases classified elsewhere
0.642 0.358 0.000
L83 Acanthosis nigricans
0.642 0.358 0.000
L80 Vitiligo
0.642 0.358 0.000
H25.2 Senile cataract, morgagnian type
0.641 0.358 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.641 0.359 0.000
T59 Toxic effect of other gases, fumes and vapours
0.639 0.361 0.000
A41.1 Septicaemia due to other specified staphylococcus
0.639 0.361 0.000
M06.8 Other specified rheumatoid arthritis
0.639 0.361 0.000
M06.4 Inflammatory polyarthropathy
0.639 0.361 0.000
M06.3 Rheumatoid nodule
0.639 0.361 0.000
M06.2 Rheumatoid bursitis
0.639 0.361 0.000
M06.1 Adult-onset Still's disease
0.639 0.361 0.000
R50-R69 General symptoms and signs
0.637 0.363 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.637 0.363 0.000
N84 Polyp of female genital tract
0.637 0.363 0.000
M54.4 Lumbago with sciatica
0.636 0.364 0.000
A48 Other bacterial diseases, not elsewhere classified
0.636 0.364 0.000
A44 Bartonellosis
0.636 0.364 0.000
A43 Nocardiosis
0.636 0.364 0.000
A42 Actinomycosis
0.636 0.364 0.000
A40 Streptococcal septicaemia
0.636 0.364 0.000
A39 Meningococcal infection
0.636 0.364 0.000
A37 Whooping cough
0.636 0.364 0.000
A36 Diphtheria
0.636 0.364 0.000
A32 Listeriosis
0.636 0.364 0.000
A31 Infection due to other mycobacteria
0.636 0.364 0.000
A30 Leprosy [Hansen's disease]
0.636 0.364 0.000
A38 Scarlet fever
0.636 0.364 0.000
A35 Other tetanus
0.636 0.364 0.000
A34 Obstetrical tetanus
0.636 0.364 0.000
A33 Tetanus neonatorum
0.636 0.364 0.000
M45 Ankylosing spondylitis
0.636 0.364 0.000
N32.3 Diverticulum of bladder
0.635 0.365 0.000
M06.0 Seronegative rheumatoid arthritis
0.634 0.366 0.000
Y83.9 Surgical procedure, unspecified
0.634 0.366 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.633 0.367 0.000
T86.1 Kidney transplant failure and rejection
0.632 0.367 0.000
B16 Acute hepatitis B
0.632 0.367 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.631 0.369 0.000
Y43.3 Other antineoplastic drugs
0.631 0.369 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.631 0.369 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.631 0.369 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.631 0.369 0.000
A08 Viral and other specified intestinal infections
0.630 0.369 0.000
M49 Spondylopathies in diseases classified elsewhere
0.630 0.370 0.000
I05 Rheumatic mitral valve diseases
0.629 0.371 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.628 0.372 0.000
S26 Injury of heart
0.628 0.372 0.000
S25 Injury of blood vessels of thorax
0.628 0.372 0.000
S24 Injury of nerves and spinal cord at thorax level
0.628 0.372 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.628 0.372 0.000
S21 Open wound of thorax
0.628 0.372 0.000
H01 Other inflammation of eyelid
0.628 0.372 0.000
J30 Vasomotor and allergic rhinitis
0.627 0.373 0.000
L40-L45 Papulosquamous disorders
0.626 0.374 0.000
H43-H45 Disorders of vitreous body and globe
0.625 0.375 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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