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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs111561475
log Bayes Factor = 1.31769
Chromosome 11   position 21,956,958  (GRCh37) Explore rs111561475 on Ensembl!
Variant rs111561475 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XV Pregnancy, childbirth and the puerperium
0.946 0.054 0.000
# Top node
0.944 0.056 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.943 0.057 0.000
O60-O75 Complications of labour and delivery
0.943 0.057 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.942 0.058 0.000
M05-M14 Inflammatory polyarthropathies
0.939 0.061 0.000
M06 Other rheumatoid arthritis
0.935 0.065 0.000
M06.9 Rheumatoid arthritis, unspecified
0.930 0.070 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.925 0.075 0.000
Chapter VII Diseases of the eye and adnexa
0.916 0.084 0.000
S80-S89 Injuries to the knee and lower leg
0.907 0.093 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.902 0.098 0.000
M15-M19 Arthrosis
0.901 0.099 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.901 0.099 0.000
M16 Coxarthrosis [arthrosis of hip]
0.900 0.100 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.897 0.103 0.000
M16.0 Primary coxarthrosis, bilateral
0.885 0.115 0.000
O63 Long labour
0.870 0.130 0.000
M16.1 Other primary coxarthrosis
0.868 0.132 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.868 0.132 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.864 0.136 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.862 0.138 0.000
Chapter I Certain infectious and parasitic diseases
0.849 0.151 0.000
H04 Disorders of lachrymal system
0.844 0.156 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.832 0.168 0.000
O47 False labour
0.832 0.168 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.830 0.170 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.830 0.170 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.828 0.172 0.000
O63.1 Prolonged second stage (of labour)
0.826 0.174 0.000
H04.5 Stenosis and insufficiency of lachrymal passages
0.814 0.186 0.000
O48 Prolonged pregnancy
0.812 0.188 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.808 0.192 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.802 0.198 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.801 0.199 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.798 0.202 0.000
S40-S49 Injuries to the shoulder and upper arm
0.790 0.210 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.782 0.218 0.000
O42 Premature rupture of membranes
0.781 0.219 0.000
S00-S09 Injuries to the head
0.774 0.226 0.000
O72 Postpartum haemorrhage
0.769 0.231 0.000
H10-H13 Disorders of conjunctiva
0.768 0.232 0.000
O68.9 Labour and delivery complicated by foetal stress, unspecified
0.767 0.233 0.000
Chapter XX External causes of morbidity and mortality
0.767 0.233 0.000
M11 Other crystal arthropathies
0.766 0.234 0.000
M07 Psoriatic and enteropathic arthropathies
0.763 0.237 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.762 0.238 0.000
M45-M49 Spondylopathies
0.761 0.239 0.000
T40.2 Other opioids
0.760 0.240 0.000
S82 Fracture of lower leg, including ankle
0.759 0.241 0.000
S80 Superficial injury of lower leg
0.755 0.245 0.000
T79-T79 Certain early complications of trauma
0.755 0.245 0.000
O85-O92 Complications predominantly related to the puerperium
0.755 0.245 0.000
O62 Abnormalities of forces of labour
0.752 0.248 0.000
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid
0.752 0.248 0.000
B95-B98 Bacterial, viral and other infectious agents
0.751 0.249 0.000
T51 Toxic effect of alcohol
0.749 0.251 0.000
H43-H45 Disorders of vitreous body and globe
0.748 0.252 0.000
M05 Seropositive rheumatoid arthritis
0.741 0.259 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.740 0.260 0.000
S83.2 Tear of meniscus, current
0.739 0.261 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.737 0.263 0.000
M86-M90 Other osteopathies
0.732 0.268 0.000
S90-S99 Injuries to the ankle and foot
0.728 0.272 0.000
S09 Other and unspecified injuries of head
0.728 0.272 0.000
S82.6 Fracture of lateral malleolus
0.725 0.275 0.000
H50 Other strabismus
0.724 0.276 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.723 0.277 0.000
Q80-Q89 Other congenital malformations
0.723 0.277 0.000
M06.4 Inflammatory polyarthropathy
0.722 0.278 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.721 0.279 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.720 0.280 0.000
T92 Sequelae of injuries of upper limb
0.719 0.281 0.000
O40 Polyhydramnios
0.715 0.285 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.715 0.285 0.000
M00-M03 Infectious arthropathies
0.714 0.286 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.713 0.287 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.713 0.287 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.711 0.289 0.000
M20-M25 Other joint disorders
0.711 0.289 0.000
O44 Placenta praevia
0.711 0.289 0.000
M60-M63 Disorders of muscles
0.710 0.290 0.000
M06.0 Seronegative rheumatoid arthritis
0.708 0.292 0.000
Q50-Q56 Congenital malformations of genital organs
0.706 0.294 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.705 0.295 0.000
H25-H28 Disorders of lens
0.705 0.295 0.000
S89 Other and unspecified injuries of lower leg
0.701 0.299 0.000
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes
0.701 0.299 0.000
S82.60 Fracture of lateral malleolus (closed)
0.700 0.300 0.000
X60-X84 Intentional self-harm
0.698 0.302 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.698 0.302 0.000
O47.0 False labour before 37 completed weeks of gestation
0.696 0.304 0.000
B65-B83 Helminthiases
0.695 0.305 0.000
O64.0 Obstructed labour due to incomplete rotation of foetal head
0.695 0.305 0.000
O61 Failed induction of labour
0.694 0.305 0.000
S09.9 Unspecified injury of head
0.694 0.306 0.000
T51.0 Ethanol
0.691 0.309 0.000
O42.9 Premature rupture of membranes, unspecified
0.690 0.310 0.000
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters
0.689 0.311 0.000
H00 Hordeolum and chalazion
0.688 0.312 0.000
M91-M94 Chondropathies
0.683 0.316 0.000
H04.4 Chronic inflammation of lachrymal passages
0.681 0.319 0.000
O30 Multiple gestation
0.681 0.319 0.000
O73 Retained placenta and membranes, without haemorrhage
0.680 0.319 0.000
O47.1 False labour at or after 37 completed weeks of gestation
0.679 0.321 0.000
O68.1 Labour and delivery complicated by meconium in amniotic fluid
0.678 0.322 0.000
M16.3 Other dysplastic coxarthrosis
0.677 0.323 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.677 0.323 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.676 0.323 0.000
S81 Open wound of lower leg
0.676 0.324 0.000
T33-T35 Frostbite
0.676 0.324 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.676 0.324 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.676 0.324 0.000
T00-T07 Injuries involving multiple body regions
0.676 0.324 0.000
S10-S19 Injuries to the neck
0.676 0.324 0.000
O74 Complications of anaesthesia during labour and delivery
0.676 0.324 0.000
O71 Other obstetric trauma
0.676 0.324 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.676 0.324 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.676 0.324 0.000
O60 Preterm delivery
0.676 0.324 0.000
M14 Arthropathies in other diseases classified elsewhere
0.673 0.327 0.000
M12 Other specific arthropathies
0.673 0.327 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.673 0.327 0.000
M08 Juvenile arthritis
0.673 0.327 0.000
M10 Gout
0.671 0.329 0.000
Chapter II Neoplasms
0.671 0.329 0.000
M06.8 Other specified rheumatoid arthritis
0.670 0.330 0.000
M06.3 Rheumatoid nodule
0.670 0.330 0.000
M06.2 Rheumatoid bursitis
0.670 0.330 0.000
M06.1 Adult-onset Still's disease
0.670 0.330 0.000
O36 Maternal care for other known or suspected foetal problems
0.668 0.331 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.667 0.333 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.667 0.333 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.667 0.333 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.667 0.333 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.667 0.333 0.000
O80-O84 Delivery
0.666 0.334 0.000
S50-S59 Injuries to the elbow and forearm
0.665 0.335 0.000
H04.3 Acute and unspecified inflammation of lachrymal passages
0.665 0.335 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.665 0.335 0.000
Q23 Congenital malformations of aortic and mitral valves
0.664 0.335 0.000
T93 Sequelae of injuries of lower limb
0.664 0.336 0.000
O45 Premature separation of placenta [abruptio placentae]
0.663 0.337 0.000
O43 Placental disorders
0.663 0.337 0.000
O41 Other disorders of amniotic fluid and membranes
0.663 0.337 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.663 0.337 0.000
O33 Maternal care for known or suspected disproportion
0.663 0.337 0.000
O31 Complications specific to multiple gestation
0.663 0.337 0.000
H04.2 Epiphora
0.662 0.338 0.000
Q27 Other congenital malformations of peripheral vascular system
0.662 0.338 0.000
S70-S79 Injuries to the hip and thigh
0.662 0.338 0.000
T40.4 Other synthetic narcotics
0.662 0.338 0.000
M24 Other specific joint derangements
0.661 0.339 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.659 0.341 0.000
O47.9 False labour, unspecified
0.653 0.347 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.652 0.348 0.000
H05 Disorders of orbit
0.652 0.348 0.000
O75.7 Vaginal delivery following previous Caesarean section
0.652 0.348 0.000
H55-H59 Other disorders of eye and adnexa
0.651 0.349 0.000
S88 Traumatic amputation of lower leg
0.650 0.350 0.000
S87 Crushing injury of lower leg
0.650 0.350 0.000
S86 Injury of muscle and tendon at lower leg level
0.650 0.350 0.000
S85 Injury of blood vessels at lower leg level
0.650 0.350 0.000
S84 Injury of nerves at lower leg level
0.650 0.350 0.000
H44 Disorders of globe
0.650 0.350 0.000
S80.9 Superficial injury of lower leg, unspecified
0.649 0.350 0.000
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified
0.649 0.351 0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.649 0.351 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.649 0.351 0.000
M16.7 Other secondary coxarthrosis
0.648 0.352 0.000
A30-A49 Other bacterial diseases
0.648 0.352 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.647 0.353 0.000
M15 Polyarthrosis
0.646 0.354 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.646 0.354 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.646 0.354 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.646 0.354 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.646 0.354 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.646 0.354 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.646 0.354 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.646 0.354 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.646 0.354 0.000
T36 Poisoning by systemic antibiotics
0.646 0.354 0.000
M16.6 Other secondary coxarthrosis, bilateral
0.645 0.355 0.000
M16.5 Other posttraumatic coxarthrosis
0.645 0.355 0.000
M16.4 Posttraumatic coxarthrosis, bilateral
0.645 0.355 0.000
M16.2 Coxarthrosis resulting from dysplasia, bilateral
0.645 0.355 0.000
Chapter XXII Codes for special purposes
0.645 0.355 0.000
O66 Other obstructed labour
0.645 0.355 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.643 0.357 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.643 0.357 0.000
Q60-Q64 Congenital malformations of the urinary system
0.643 0.357 0.000
Q35-Q37 Cleft lip and cleft palate
0.643 0.357 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.643 0.357 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.643 0.357 0.000
Q00-Q07 Congenital malformations of the nervous system
0.643 0.357 0.000
M40-M43 Deforming dorsopathies
0.643 0.357 0.000
M11.2 Other chondrocalcinosis
0.642 0.358 0.000
Chapter VI Diseases of the nervous system
0.640 0.360 0.000
M07.3 Other psoriatic arthropathies
0.637 0.363 0.000
T39.0 Salicylates
0.636 0.364 0.000
O63.0 Prolonged first stage (of labour)
0.634 0.366 0.000
M47 Spondylosis
0.634 0.366 0.000
O69.1 Labour and delivery complicated by cord around neck, with compression
0.633 0.366 0.000
H11 Other disorders of conjunctiva
0.633 0.367 0.000
D00-D09 In situ neoplasms
0.632 0.368 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.631 0.369 0.000
A80-A89 Viral infections of the central nervous system
0.631 0.369 0.000
S42 Fracture of shoulder and upper arm
0.631 0.369 0.000
Q28 Other congenital malformations of circulatory system
0.629 0.371 0.000
O75.8 Other specified complications of labour and delivery
0.628 0.371 0.000
O72.1 Other immediate postpartum haemorrhage
0.627 0.372 0.000
O63.2 Delayed delivery of second twin, triplet, etc.
0.624 0.376 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.623 0.377 0.000
O68.3 Labour and delivery complicated by biochemical evidence of foetal stress
0.622 0.378 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.621 0.379 0.000
H03 Disorders of eyelid in diseases classified elsewhere
0.620 0.380 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.619 0.381 0.000
O87 Venous complications in the puerperium
0.618 0.382 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.616 0.384 0.000
T92.2 Sequelae of fracture at wrist and hand level
0.616 0.384 0.000
O62.2 Other uterine inertia
0.616 0.384 0.000
S40 Superficial injury of shoulder and upper arm
0.615 0.385 0.000
H01 Other inflammation of eyelid
0.615 0.385 0.000
M80-M85 Disorders of bone density and structure
0.615 0.385 0.000
X62.9 Unspecified place
0.614 0.386 0.000
O42.1 Premature rupture of membranes, onset of labour after 24 hours
0.614 0.386 0.000
A00-A09 Intestinal infectious diseases
0.614 0.386 0.000
H50.9 Strabismus, unspecified
0.613 0.387 0.000
B99-B99 Other infectious diseases
0.609 0.391 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.609 0.391 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.609 0.391 0.000
B50-B64 Protozoal diseases
0.609 0.391 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.609 0.391 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.609 0.391 0.000
A75-A79 Rickettsioses
0.609 0.391 0.000
A70-A74 Other diseases caused by chlamydiae
0.609 0.391 0.000
A65-A69 Other spirochaetal diseases
0.609 0.391 0.000
A20-A28 Certain zoonotic bacterial diseases
0.609 0.391 0.000
A15-A19 Tuberculosis
0.609 0.391 0.000
T66-T78 Other and unspecified effects of external causes
0.607 0.393 0.000
H04.9 Disorder of lachrymal system, unspecified
0.605 0.395 0.000
H04.8 Other disorders of lachrymal system
0.605 0.395 0.000
H04.6 Other changes in lachrymal passages
0.605 0.395 0.000
H04.0 Dacryoadenitis
0.605 0.395 0.000
O24 Diabetes mellitus in pregnancy
0.605 0.395 0.000
B35-B49 Mycoses
0.603 0.397 0.000
Q21 Congenital malformations of cardiac septa
0.602 0.398 0.000
S20-S29 Injuries to the thorax
0.602 0.398 0.000
T90 Sequelae of injuries of head
0.601 0.398 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.601 0.399 0.000
H49 Paralytic strabismus
0.601 0.399 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.599 0.401 0.000
H10 Conjunctivitis
0.598 0.402 0.000
Chapter VIII Diseases of the ear and mastoid process
0.598 0.402 0.000
T98 Sequelae of other and unspecified effects of external causes
0.597 0.403 0.000
T95 Sequelae of burns, corrosions and frostbite
0.597 0.403 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.597 0.403 0.000
T91 Sequelae of injuries of neck and trunk
0.597 0.403 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.597 0.403 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.597 0.403 0.000
S82.3 Fracture of lower end of tibia
0.595 0.405 0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]
0.595 0.405 0.000
T40.8 Lysergide [LSD]
0.595 0.405 0.000
T40.7 Cannabis (derivatives)
0.595 0.405 0.000
T40.6 Other and unspecified narcotics
0.595 0.405 0.000
T40.5 Cocaine
0.595 0.405 0.000
T40.3 Methadone
0.595 0.405 0.000
T40.1 Heroin
0.595 0.405 0.000
T40.0 Opium
0.595 0.405 0.000
T65 Toxic effect of other and unspecified substances
0.595 0.405 0.000
T63 Toxic effect of contact with venomous animals
0.595 0.405 0.000
T62 Toxic effect of other noxious substances eaten as food
0.595 0.405 0.000
T61 Toxic effect of noxious substances eaten as seafood
0.595 0.405 0.000
T60 Toxic effect of pesticides
0.595 0.405 0.000
T59 Toxic effect of other gases, fumes and vapours
0.595 0.405 0.000
T57 Toxic effect of other inorganic substances
0.595 0.405 0.000
T56 Toxic effect of metals
0.595 0.405 0.000
T54 Toxic effect of corrosive substances
0.595 0.405 0.000
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone
0.595 0.405 0.000
T52 Toxic effect of organic solvents
0.595 0.405 0.000
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants
0.595 0.405 0.000
T58 Toxic effect of carbon monoxide
0.595 0.405 0.000
T55 Toxic effect of soaps and detergents
0.595 0.405 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.594 0.406 0.000
O75.9 Complication of labour and delivery, unspecified
0.594 0.406 0.000
O75.5 Delayed delivery after artificial rupture of membranes
0.594 0.406 0.000
O75.4 Other complications of obstetric surgery and procedures
0.594 0.406 0.000
O75.3 Other infection during labour
0.594 0.406 0.000
O75.2 Pyrexia during labour, not elsewhere classified
0.594 0.406 0.000
O75.1 Shock during or following labour and delivery
0.594 0.406 0.000
O75.0 Maternal distress during labour and delivery
0.594 0.406 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.593 0.407 0.000
W20-W49 Exposure to inanimate mechanical forces
0.591 0.409 0.000
M47.9 Spondylosis, unspecified
0.589 0.410 0.000
V10-V19 Pedal cyclist injured in transport accident
0.589 0.411 0.000
M21 Other acquired deformities of limbs
0.587 0.413 0.000
B80 Enterobiasis
0.584 0.416 0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters
0.584 0.416 0.000
H50.0 Convergent concomitant strabismus
0.584 0.416 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.583 0.417 0.000
Q38 Other congenital malformations of tongue, mouth and pharynx
0.582 0.418 0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.581 0.419 0.000
B15-B19 Viral hepatitis
0.581 0.419 0.000
M50-M54 Other dorsopathies
0.579 0.420 0.000
Q26 Congenital malformations of great veins
0.579 0.421 0.000
Q25 Congenital malformations of great arteries
0.579 0.421 0.000
Q24 Other congenital malformations of heart
0.579 0.421 0.000
Q22 Congenital malformations of pulmonary and tricuspid valves
0.579 0.421 0.000
Q20 Congenital malformations of cardiac chambers and connexions
0.579 0.421 0.000
G90-G99 Other disorders of the nervous system
0.579 0.421 0.000
M16.9 Coxarthrosis, unspecified
0.577 0.423 0.000
S92 Fracture of foot, except ankle
0.577 0.423 0.000
O72.2 Delayed and secondary postpartum haemorrhage
0.577 0.423 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.576 0.424 0.000
H16 Keratitis
0.576 0.424 0.000
H30-H36 Disorders of choroid and retina
0.575 0.425 0.000
H51 Other disorders of binocular movement
0.575 0.425 0.000
S83.7 Injury to multiple structures of knee
0.574 0.426 0.000
S83.6 Sprain and strain of other and unspecified parts of knee
0.574 0.426 0.000
S83.4 Sprain and strain involving (fibular)(tibial) collateral ligamnent of knee
0.574 0.426 0.000
S83.3 Tear of articular cartilage of knee, current
0.574 0.426 0.000
S83.1 Dislocation of knee
0.574 0.426 0.000
S83.0 Dislocation of patella
0.574 0.426 0.000
G70-G73 Diseases of myoneural junction and muscle
0.573 0.427 0.000
H50.1 Divergent concomitant strabismus
0.572 0.427 0.000
O64.9 Obstructed labour due to malposition and malpresentation, unspecified
0.572 0.428 0.000
O64.8 Obstructed labour due to other malposition and malpresentation
0.572 0.428 0.000
O64.5 Obstructed labour due to compound presentation
0.572 0.428 0.000
O64.4 Obstructed labour due to shoulder presentation
0.572 0.428 0.000
O64.3 Obstructed labour due to brow presentation
0.572 0.428 0.000
O64.2 Obstructed labour due to face presentation
0.572 0.428 0.000
O64.1 Obstructed labour due to breech presentation
0.572 0.428 0.000
O68.0 Labour and delivery complicated by foetal heart rate anomaly
0.572 0.428 0.000
O68.8 Labour and delivery complicated by other evidence of foetal stress
0.572 0.428 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.571 0.429 0.000
M24.1 Other articular cartilage disorders
0.571 0.429 0.000
M86 Osteomyelitis
0.571 0.429 0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.569 0.431 0.000
M45 Ankylosing spondylitis
0.569 0.431 0.000
I60-I69 Cerebrovascular diseases
0.569 0.431 0.000
Q85 Phakomatoses, not elsewhere classified
0.568 0.432 0.000
Chapter IX Diseases of the circulatory system
0.567 0.433 0.000
W00-W19 Falls
0.567 0.433 0.000
S42.2 Fracture of upper end of humerus
0.567 0.433 0.000
O63.9 Long labour, unspecified
0.566 0.433 0.000
T39.1 4-Aminophenol derivatives
0.567 0.433 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.566 0.433 0.000
S48 Traumatic amputation of shoulder and upper arm
0.566 0.433 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.566 0.433 0.000
S45 Injury of blood vessels at shoulder and upper arm level
0.566 0.433 0.000
S44 Injury of nerves at shoulder and upper arm level
0.566 0.433 0.000
S41 Open wound of shoulder and upper arm
0.566 0.433 0.000
S47 Crushing injury of shoulder and upper arm
0.566 0.433 0.000
H44.0 Purulent endophthalmitis
0.565 0.434 0.000
Q23.1 Congenital insufficiency of aortic valve
0.562 0.438 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.562 0.438 0.000
M47.99 Spondylosis, unspecified (Site unspecified)
0.561 0.439 0.000
M35 Other systemic involvement of connective tissue
0.561 0.439 0.000
S60-S69 Injuries to the wrist and hand
0.560 0.440 0.000
M46 Other inflammatory spondylopathies
0.560 0.440 0.000
O42.2 Premature rupture of membranes, labour delayed by therapy
0.560 0.440 0.000
Q82 Other congenital malformations of skin
0.559 0.441 0.000
Q27.3 Peripheral arteriovenous malformation
0.558 0.442 0.000
S82.4 Fracture of fibula alone
0.558 0.442 0.000
T92.0 Sequelae of open wound of upper limb
0.558 0.442 0.000
H27 Other disorders of lens
0.557 0.443 0.000
O44.1 Placenta praevia with haemorrhage
0.557 0.443 0.000
S08 Traumatic amputation of part of head
0.555 0.445 0.000
S07 Crushing injury of head
0.555 0.445 0.000
S05 Injury of eye and orbit
0.555 0.445 0.000
S04 Injury of cranial nerves
0.555 0.445 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.555 0.445 0.000
S06 Intracranial injury
0.554 0.446 0.000
S89.9 Unspecified injury of lower leg
0.554 0.446 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.553 0.447 0.000
M11.26 Other chondrocalcinosis (Lower leg)
0.553 0.447 0.000
H00.0 Hordeolum and other deep inflammation of eyelid
0.553 0.447 0.000
M65-M68 Disorders of synovium and tendon
0.552 0.448 0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments
0.552 0.448 0.000
O72.3 Postpartum coagulation defects
0.551 0.449 0.000
O72.0 Third-stage haemorrhage
0.551 0.449 0.000
H13 Disorders of conjunctiva in diseases classified elsewhere
0.551 0.449 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.550 0.450 0.000
Y35-Y36 Legal intervention and operations of war
0.550 0.450 0.000
Y10-Y34 Event of undetermined intent
0.550 0.450 0.000
Y00-Y09 Assault
0.550 0.450 0.000
X85-X99 Assault
0.550 0.450 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.550 0.450 0.000
X50-X57 Overexertion, travel and privation
0.550 0.450 0.000
X30-X39 Exposure to forces of nature
0.550 0.450 0.000
X20-X29 Contact with venomous animals and plants
0.550 0.450 0.000
X10-X19 Contact with heat and hot substances
0.550 0.450 0.000
X00-X09 Exposure to smoke, fire and flames
0.550 0.450 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.550 0.450 0.000
W75-W84 Other accidental threats to breathing
0.550 0.450 0.000
W65-W74 Accidental drowning and submersion
0.550 0.450 0.000
W50-W64 Exposure to animate mechanical forces
0.550 0.450 0.000
V98-V99 Other and unspecified transport accidents
0.550 0.450 0.000
V95-V97 Air and space transport accidents
0.550 0.450 0.000
V90-V94 Water transport accidents
0.550 0.450 0.000
V70-V79 Bus occupant injured in transport accident
0.550 0.450 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.550 0.450 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.550 0.450 0.000
V40-V49 Car occupant injured in transport accident
0.550 0.450 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.550 0.450 0.000
V01-V09 Pedestrian injured in transport accident
0.550 0.450 0.000
M00 Pyogenic arthritis
0.550 0.450 0.000
H26 Other cataract
0.550 0.450 0.000
M11.9 Crystal arthropathy, unspecified
0.549 0.451 0.000
M11.8 Other specified crystal arthropathies
0.549 0.451 0.000
M11.1 Familial chondrocalcinosis
0.549 0.451 0.000
M11.0 Hydroxyapatite deposition disease
0.549 0.451 0.000
I63 Cerebral infarction
0.548 0.452 0.000
M07.6 Other enteropathic arthropathies
0.547 0.453 0.000
M07.5 Arthropathy in ulcerative colitis
0.547 0.453 0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.547 0.453 0.000
M07.2 Psoriatic spondylitis
0.547 0.453 0.000
M07.1 Arthritis mutilans
0.547 0.453 0.000
M07.0 Distal interphalangeal psoriatic arthropathy
0.547 0.453 0.000
O81 Single delivery by forceps and vacuum extractor
0.547 0.453 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.547 0.453 0.000
V80-V89 Other land transport accidents
0.546 0.453 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.546 0.453 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.546 0.453 0.000
T39.4 Antirheumatics, not elsewhere classified
0.546 0.453 0.000
T39.2 Pyrazolone derivatives
0.546 0.453 0.000
A04 Other bacterial intestinal infections
0.546 0.454 0.000
D05 Carcinoma in situ of breast
0.546 0.454 0.000
M49 Spondylopathies in diseases classified elsewhere
0.545 0.455 0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.545 0.455 0.000
T14 Injury of unspecified body region
0.544 0.455 0.000
S82.9 Fracture of lower leg, part unspecified
0.544 0.456 0.000
S82.7 Multiple fractures of lower leg
0.544 0.456 0.000
C60-C63 Malignant neoplasms of male genital organs
0.544 0.456 0.000
M62 Other disorders of muscle
0.543 0.457 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.543 0.457 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.542 0.458 0.000
S80.7 Multiple superficial injuries of lower leg
0.542 0.458 0.000
S80.1 Contusion of other and unspecified parts of lower leg
0.542 0.458 0.000
S80.0 Contusion of knee
0.542 0.458 0.000
O92 Other disorders of breast and lactation associated with childbirth
0.541 0.459 0.000
O91 Infections of breast associated with childbirth
0.541 0.459 0.000
O90 Complications of the puerperium, not elsewhere classified
0.541 0.459 0.000
O89 Complications of anaesthesia during the puerperium
0.541 0.459 0.000
O88 Obstetric embolism
0.541 0.459 0.000
O86 Other puerperal infections
0.541 0.459 0.000
O85 Puerperal sepsis
0.541 0.459 0.000
M88 Paget's disease of bone [osteitis deformans]
0.540 0.459 0.000
B25-B34 Other viral diseases
0.539 0.460 0.000
O62.9 Abnormality of forces of labour, unspecified
0.539 0.460 0.000
O62.8 Other abnormalities of forces of labour
0.539 0.460 0.000
O62.4 Hypertonic, incoordinate and prolonged uterine contractions
0.539 0.460 0.000
O62.3 Precipitate labour
0.539 0.460 0.000
O62.1 Secondary uterine inertia
0.539 0.460 0.000
O62.0 Primary inadequate contractions
0.539 0.460 0.000
I63.9 Cerebral infarction, unspecified
0.538 0.462 0.000
T51.9 Alcohol, unspecified
0.537 0.463 0.000
T51.8 Other alcohols
0.537 0.463 0.000
T51.3 Fusel oil
0.537 0.463 0.000
T51.2 2-Propanol
0.537 0.463 0.000
T51.1 Methanol
0.537 0.463 0.000
M89 Other disorders of bone
0.537 0.463 0.000
S80.8 Other superficial injuries of lower leg
0.537 0.463 0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified
0.537 0.463 0.000
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.536 0.463 0.000
H18 Other disorders of cornea
0.535 0.465 0.000
H53-H54 Visual disturbances and blindness
0.535 0.465 0.000
O46.9 Antepartum haemorrhage, unspecified
0.534 0.466 0.000
S50 Superficial injury of forearm
0.534 0.466 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.533 0.467 0.000
O00-O08 Pregnancy with abortive outcome
0.532 0.467 0.000
H52 Disorders of refraction and accommodation
0.532 0.468 0.000
A63 Other predominantly sexually transmitted diseases, not elsewhere classified
0.532 0.468 0.000
D04 Carcinoma in situ of skin
0.532 0.468 0.000
M05.8 Other seropositive rheumatoid arthritis
0.531 0.469 0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.531 0.469 0.000
M05.2 Rheumatoid vasculitis
0.531 0.469 0.000
M05.1 Rheumatoid lung disease
0.531 0.469 0.000
M05.0 Felty's syndrome
0.531 0.469 0.000
H04.1 Other disorders of lachrymal gland
0.531 0.469 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.531 0.469 0.000
S01 Open wound of head
0.530 0.470 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.530 0.470 0.000
D06 Carcinoma in situ of cervix uteri
0.529 0.470 0.000
M07.39 Other psoriatic arthropathies (Site unspecified)
0.529 0.471 0.000
O69.9 Labour and delivery complicated by cord complication, unspecified
0.528 0.471 0.000
O69.8 Labour and delivery complicated by other cord complications
0.528 0.471 0.000
O69.5 Labour and delivery complicated by vascular lesion of cord
0.528 0.471 0.000
O69.4 Labour and delivery complicated by vasa praevia
0.528 0.471 0.000
O69.3 Labour and delivery complicated by short cord
0.528 0.471 0.000
O69.0 Labour and delivery complicated by prolapse of cord
0.528 0.471 0.000
Q51 Congenital malformations of uterus and cervix
0.528 0.472 0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters
0.527 0.473 0.000
M25 Other joint disorders, not elsewhere classified
0.526 0.474 0.000
M90 Osteopathies in diseases classified elsewhere
0.525 0.475 0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters
0.525 0.475 0.000
G70 Myasthenia gravis and other myoneural disorders
0.524 0.476 0.000
A40 Streptococcal septicaemia
0.523 0.477 0.000
S99 Other and unspecified injuries of ankle and foot
0.522 0.478 0.000
S98 Traumatic amputation of ankle and foot
0.522 0.478 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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