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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs1117139
log Bayes Factor = 19.2993
Chromosome 4   position 160,589,307  (GRCh37) Explore rs1117139 on Ensembl!
Variant rs1117139 is part of Cluster X0232

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter V Mental and behavioural disorders
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
F10 Mental and behavioural disorders due to use of alcohol
1.000 0.000 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.999 0.001 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.998 0.002 0.000
R50-R69 General symptoms and signs
0.998 0.002 0.000
Chapter VI Diseases of the nervous system
0.998 0.002 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.997 0.003 0.000
R00 Abnormalities of heart beat
0.994 0.006 0.000
F30-F39 Mood [affective] disorders
0.994 0.006 0.000
R63 Symptoms and signs concerning food and fluid intake
0.989 0.011 0.000
G40-G47 Episodic and paroxysmal disorders
0.989 0.011 0.000
F10.1 Harmful use
0.988 0.012 0.000
Chapter IX Diseases of the circulatory system
0.987 0.013 0.000
R00.0 Tachycardia, unspecified
0.987 0.013 0.000
F31 Bipolar affective disorder
0.984 0.016 0.000
F10.2 Dependence syndrome
0.982 0.018 0.000
F10.0 Acute intoxication
0.982 0.018 0.000
M45-M49 Spondylopathies
0.974 0.026 0.000
R63.4 Abnormal weight loss
0.972 0.028 0.000
Chapter XX External causes of morbidity and mortality
0.970 0.030 0.000
R60 Oedema, not elsewhere classified
0.966 0.034 0.000
M70-M79 Other soft tissue disorders
0.965 0.035 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.964 0.036 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.961 0.039 0.000
R12 Heartburn
0.950 0.050 0.000
I95 Hypotension
0.947 0.053 0.000
G90-G99 Other disorders of the nervous system
0.944 0.056 0.000
R00.2 Palpitations
0.943 0.057 0.000
R30-R39 Symptoms and signs involving the urinary system
0.942 0.058 0.000
R60.0 Localised oedema
0.937 0.063 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.931 0.069 0.000
G43 Migraine
0.931 0.069 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.930 0.070 0.000
Chapter VIII Diseases of the ear and mastoid process
0.927 0.073 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.926 0.074 0.000
R32 Unspecified urinary incontinence
0.926 0.074 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.925 0.075 0.000
Chapter I Certain infectious and parasitic diseases
0.920 0.080 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.918 0.082 0.000
F31.9 Bipolar affective disorder, unspecified
0.918 0.082 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.917 0.083 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.913 0.087 0.000
R55 Syncope and collapse
0.911 0.089 0.000
I95.9 Hypotension, unspecified
0.911 0.089 0.000
T66-T78 Other and unspecified effects of external causes
0.904 0.095 0.000
R51 Headache
0.904 0.096 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.903 0.097 0.000
M47 Spondylosis
0.903 0.097 0.000
S00-S09 Injuries to the head
0.898 0.102 0.000
M45 Ankylosing spondylitis
0.897 0.103 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.894 0.106 0.000
S80-S89 Injuries to the knee and lower leg
0.893 0.107 0.000
G43.9 Migraine, unspecified
0.890 0.110 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.887 0.113 0.000
G40 Epilepsy
0.885 0.115 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.874 0.126 0.000
M20-M25 Other joint disorders
0.873 0.127 0.000
R13 Dysphagia
0.868 0.132 0.000
I95.1 Orthostatic hypotension
0.867 0.133 0.000
M79.8 Other specified soft tissue disorders
0.866 0.134 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.865 0.135 0.000
S90-S99 Injuries to the ankle and foot
0.865 0.135 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.861 0.139 0.000
F10.4 Withdrawal state with delirium
0.861 0.139 0.000
H65-H75 Diseases of middle ear and mastoid
0.859 0.141 0.000
Chapter VII Diseases of the eye and adnexa
0.857 0.143 0.000
T39.1 4-Aminophenol derivatives
0.857 0.143 0.000
F10.3 Withdrawal state
0.853 0.147 0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms
0.851 0.149 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.850 0.150 0.000
R63.8 Other symptoms and signs concerning food and fluid intake
0.848 0.152 0.000
S70-S79 Injuries to the hip and thigh
0.848 0.152 0.000
F31.6 Bipolar affective disorder, current episode mixed
0.847 0.153 0.000
I78 Diseases of capillaries
0.844 0.156 0.000
T42.4 Benzodiazepines
0.843 0.157 0.000
M45.X9 Ankylosing spondylitis (Site unspecified)
0.841 0.159 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.841 0.159 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.840 0.160 0.000
G93 Other disorders of brain
0.840 0.160 0.000
M47.2 Other spondylosis with radiculopathy
0.837 0.163 0.000
V10-V19 Pedal cyclist injured in transport accident
0.835 0.165 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.834 0.166 0.000
M20 Acquired deformities of fingers and toes
0.833 0.167 0.000
S01 Open wound of head
0.832 0.168 0.000
T78 Adverse effects, not elsewhere classified
0.824 0.176 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.823 0.177 0.000
F32 Depressive episode
0.822 0.178 0.000
M40-M43 Deforming dorsopathies
0.822 0.178 0.000
R11 Nausea and vomiting
0.821 0.179 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.820 0.180 0.000
M80-M85 Disorders of bone density and structure
0.820 0.180 0.000
R39 Other symptoms and signs involving the urinary system
0.819 0.181 0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms
0.819 0.181 0.000
R07 Pain in throat and chest
0.818 0.182 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.814 0.186 0.000
R20 Disturbances of skin sensation
0.813 0.187 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.813 0.187 0.000
R63.5 Abnormal weight gain
0.810 0.190 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.803 0.197 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.802 0.198 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.802 0.198 0.000
A30-A49 Other bacterial diseases
0.800 0.200 0.000
M20.5 Other deformities of toe(s) (acquired)
0.799 0.201 0.000
M86-M90 Other osteopathies
0.798 0.202 0.000
I70 Atherosclerosis
0.797 0.203 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.796 0.204 0.000
G91 Hydrocephalus
0.796 0.204 0.000
M79.87 Other specified soft tissue disorders (Ankle and foot)
0.795 0.205 0.000
S82 Fracture of lower leg, including ankle
0.794 0.206 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.792 0.208 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.792 0.208 0.000
F33 Recurrent depressive disorder
0.791 0.209 0.000
R94 Abnormal results of function studies
0.790 0.210 0.000
M20.4 Other hammer toe(s) (acquired)
0.789 0.211 0.000
W00-W19 Falls
0.787 0.213 0.000
M65-M68 Disorders of synovium and tendon
0.786 0.214 0.000
F60-F69 Disorders of adult personality and behaviour
0.786 0.214 0.000
M47.9 Spondylosis, unspecified
0.784 0.216 0.000
R23 Other skin changes
0.784 0.216 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.783 0.217 0.000
T40.6 Other and unspecified narcotics
0.782 0.218 0.000
I78.1 Naevus, nonneoplastic
0.782 0.218 0.000
H90-H95 Other disorders of ear
0.781 0.219 0.000
H65 Nonsuppurative otitis media
0.781 0.219 0.000
T79-T79 Certain early complications of trauma
0.779 0.221 0.000
M21 Other acquired deformities of limbs
0.778 0.222 0.000
R57 Shock, not elsewhere classified
0.778 0.222 0.000
I30-I52 Other forms of heart disease
0.777 0.223 0.000
R03.0 Elevated blood-pressure reading, without diagnosis of hypertension
0.777 0.223 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.777 0.223 0.000
Y86 Sequelae of other accidents
0.775 0.225 0.000
I80 Phlebitis and thrombophlebitis
0.775 0.225 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.774 0.226 0.000
M47.22 Other spondylosis with radiculopathy (Cervical region)
0.771 0.229 0.000
B25-B34 Other viral diseases
0.770 0.229 0.000
M48 Other spondylopathies
0.770 0.230 0.000
Q50-Q56 Congenital malformations of genital organs
0.767 0.233 0.000
G45.4 Transient global amnesia
0.766 0.234 0.000
B95-B98 Bacterial, viral and other infectious agents
0.766 0.234 0.000
H71 Cholesteatoma of middle ear
0.765 0.235 0.000
T78.4 Allergy, unspecified
0.764 0.236 0.000
F31.0 Bipolar affective disorder, current episode hypomanic
0.763 0.237 0.000
G93.3 Postviral fatigue syndrome
0.762 0.238 0.000
R47-R49 Symptoms and signs involving speech and voice
0.762 0.238 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.760 0.240 0.000
T40.2 Other opioids
0.756 0.243 0.000
M60-M63 Disorders of muscles
0.756 0.244 0.000
I05-I09 Chronic rheumatic heart diseases
0.755 0.245 0.000
R39.8 Other and unspecified symptoms and signs involving the urinary system
0.754 0.246 0.000
S10-S19 Injuries to the neck
0.754 0.246 0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)
0.754 0.246 0.000
S72 Fracture of femur
0.752 0.248 0.000
R60.9 Oedema, unspecified
0.751 0.249 0.000
M77 Other enthesopathies
0.750 0.250 0.000
R54 Senility
0.750 0.250 0.000
H40-H42 Glaucoma
0.749 0.251 0.000
R09.1 Pleurisy
0.749 0.251 0.000
R50 Fever of unknown origin
0.749 0.251 0.000
S92 Fracture of foot, except ankle
0.748 0.252 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.747 0.253 0.000
G47 Sleep disorders
0.746 0.254 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.745 0.255 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.742 0.258 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.741 0.259 0.000
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities
0.740 0.260 0.000
F80-F89 Disorders of psychological development
0.739 0.260 0.000
V18 Pedal cyclist injured in noncollision transport accident
0.739 0.261 0.000
M79.0 Rheumatism, unspecified
0.737 0.263 0.000
T40.4 Other synthetic narcotics
0.735 0.265 0.000
M00-M03 Infectious arthropathies
0.734 0.266 0.000
R07.4 Chest pain, unspecified
0.733 0.267 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.732 0.268 0.000
S20-S29 Injuries to the thorax
0.730 0.270 0.000
X60-X84 Intentional self-harm
0.729 0.271 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.728 0.272 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.727 0.273 0.000
Q80-Q89 Other congenital malformations
0.726 0.274 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.726 0.274 0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.726 0.274 0.000
I72 Other aneurysm
0.725 0.275 0.000
M76 Enthesopathies of lower limb, excluding foot
0.725 0.275 0.000
G45.9 Transient cerebral ischaemic attack, unspecified
0.725 0.275 0.000
S40-S49 Injuries to the shoulder and upper arm
0.724 0.275 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.724 0.276 0.000
M79.1 Myalgia
0.724 0.276 0.000
M79.89 Other specified soft tissue disorders (Site unspecified)
0.722 0.278 0.000
X20-X29 Contact with venomous animals and plants
0.721 0.279 0.000
A41 Other septicaemia
0.721 0.279 0.000
T51 Toxic effect of alcohol
0.720 0.280 0.000
I74 Arterial embolism and thrombosis
0.720 0.280 0.000
G95 Other diseases of spinal cord
0.719 0.281 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.719 0.281 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.717 0.283 0.000
F70-F79 Mental retardation
0.717 0.283 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
F10.9 Unspecified mental and behavioural disorder
0.717 0.283 0.000
F10.8 Other mental and behavioural disorders
0.717 0.283 0.000
F10.7 Residual and late-onset psychotic disorder
0.717 0.283 0.000
F10.6 Amnesic syndrome
0.717 0.283 0.000
F10.5 Psychotic disorder
0.717 0.283 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.717 0.283 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.717 0.283 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.717 0.283 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.717 0.283 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.717 0.283 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.717 0.283 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.717 0.283 0.000
F11 Mental and behavioural disorders due to use of opioids
0.717 0.283 0.000
M91-M94 Chondropathies
0.716 0.284 0.000
M47.96 Spondylosis, unspecified (Lumbar region)
0.716 0.284 0.000
S01.9 Open wound of head, part unspecified
0.716 0.284 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.716 0.284 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.716 0.284 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.716 0.284 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.716 0.284 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.716 0.284 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.716 0.284 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.716 0.284 0.000
T36 Poisoning by systemic antibiotics
0.716 0.284 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.716 0.284 0.000
R62 Lack of expected normal physiological development
0.716 0.284 0.000
R64 Cachexia
0.716 0.284 0.000
R58 Haemorrhage, not elsewhere classified
0.716 0.284 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.715 0.284 0.000
I42 Cardiomyopathy
0.715 0.285 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.715 0.285 0.000
F38 Other mood [affective] disorders
0.712 0.287 0.000
F34 Persistent mood [affective] disorders
0.712 0.287 0.000
F30 Manic episode
0.712 0.287 0.000
F39 Unspecified mood [affective] disorder
0.712 0.287 0.000
R93.4 Abnormal findings on diagnostic imaging of urinary organs
0.712 0.288 0.000
Q21 Congenital malformations of cardiac septa
0.712 0.288 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.711 0.289 0.000
M21.0 Valgus deformity, not elsewhere classified
0.711 0.289 0.000
V80-V89 Other land transport accidents
0.711 0.289 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.710 0.290 0.000
R63.6 Insufficient intake of food and water due to self neglect
0.709 0.291 0.000
R63.3 Feeding difficulties and mismanagement
0.709 0.291 0.000
R63.2 Polyphagia
0.709 0.291 0.000
R63.1 Polydipsia
0.709 0.291 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.709 0.291 0.000
R94.3 Abnormal results of cardiovascular function studies
0.709 0.291 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.709 0.291 0.000
G41 Status epilepticus
0.709 0.291 0.000
I00-I02 Acute rheumatic fever
0.708 0.292 0.000
S82.8 Fractures of other parts of lower leg
0.707 0.293 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.707 0.293 0.000
I71 Aortic aneurysm and dissection
0.706 0.293 0.000
Chapter XXII Codes for special purposes
0.706 0.294 0.000
R03.1 Nonspecific low blood-pressure reading
0.706 0.294 0.000
F31.8 Other bipolar affective disorders
0.705 0.295 0.000
F31.7 Bipolar affective disorder, currently in remission
0.705 0.295 0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms
0.705 0.295 0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms
0.705 0.295 0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression
0.705 0.295 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.705 0.295 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.704 0.296 0.000
R26 Abnormalities of gait and mobility
0.703 0.297 0.000
R20.8 Other and unspecified disturbances of skin sensation
0.702 0.298 0.000
R46 Symptoms and signs involving appearance and behaviour
0.702 0.298 0.000
G96 Other disorders of central nervous system
0.702 0.298 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.702 0.298 0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
0.701 0.299 0.000
G70-G73 Diseases of myoneural junction and muscle
0.700 0.300 0.000
I70.2 Atherosclerosis of arteries of the extremities
0.700 0.300 0.000
M71 Other bursopathies
0.700 0.300 0.000
S89 Other and unspecified injuries of lower leg
0.699 0.301 0.000
Y88 Sequelae of surgical and medical care as external cause
0.699 0.301 0.000
M49 Spondylopathies in diseases classified elsewhere
0.698 0.302 0.000
R93.1 Abnormal findings on diagnostic imaging of heart and coronary circulation
0.698 0.302 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.698 0.302 0.000
I87 Other disorders of veins
0.697 0.303 0.000
R30 Pain associated with micturition
0.697 0.303 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.696 0.304 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.695 0.305 0.000
Y35-Y36 Legal intervention and operations of war
0.695 0.305 0.000
Y10-Y34 Event of undetermined intent
0.695 0.305 0.000
Y00-Y09 Assault
0.695 0.305 0.000
X85-X99 Assault
0.695 0.305 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.695 0.305 0.000
X50-X57 Overexertion, travel and privation
0.695 0.305 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.695 0.305 0.000
X30-X39 Exposure to forces of nature
0.695 0.305 0.000
X10-X19 Contact with heat and hot substances
0.695 0.305 0.000
X00-X09 Exposure to smoke, fire and flames
0.695 0.305 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.695 0.305 0.000
W75-W84 Other accidental threats to breathing
0.695 0.305 0.000
W65-W74 Accidental drowning and submersion
0.695 0.305 0.000
W50-W64 Exposure to animate mechanical forces
0.695 0.305 0.000
V98-V99 Other and unspecified transport accidents
0.695 0.305 0.000
V95-V97 Air and space transport accidents
0.695 0.305 0.000
V90-V94 Water transport accidents
0.695 0.305 0.000
V70-V79 Bus occupant injured in transport accident
0.695 0.305 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.695 0.305 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.695 0.305 0.000
V40-V49 Car occupant injured in transport accident
0.695 0.305 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.695 0.305 0.000
V01-V09 Pedestrian injured in transport accident
0.695 0.305 0.000
S60-S69 Injuries to the wrist and hand
0.694 0.306 0.000
R16 Hepatomegaly and splenomegaly, not elsewhere classified
0.693 0.307 0.000
R60.1 Generalised oedema
0.693 0.307 0.000
H20 Iridocyclitis
0.693 0.307 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.692 0.308 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.691 0.309 0.000
I99 Other and unspecified disorders of circulatory system
0.691 0.309 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.691 0.309 0.000
R09.8 Other specified symptoms and signs involving the circulatory and respiratory systems
0.691 0.309 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.690 0.309 0.000
G44 Other headache syndromes
0.688 0.312 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.688 0.312 0.000
G45.8 Other transient cerebral ischaemic attacks and related syndromes
0.688 0.312 0.000
S02 Fracture of skull and facial bones
0.687 0.313 0.000
T68 Hypothermia
0.686 0.313 0.000
R61 Hyperhidrosis
0.686 0.314 0.000
R00.8 Other and unspecified abnormalities of heart beat
0.685 0.315 0.000
M79.6 Pain in limb
0.685 0.315 0.000
B35-B49 Mycoses
0.685 0.315 0.000
F32.1 Moderate depressive episode
0.684 0.316 0.000
W20-W49 Exposure to inanimate mechanical forces
0.684 0.316 0.000
S01.0 Open wound of scalp
0.684 0.316 0.000
M81 Osteoporosis without pathological fracture
0.682 0.318 0.000
M79.7 Fibromyalgia
0.681 0.319 0.000
H80-H83 Diseases of inner ear
0.681 0.319 0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.680 0.320 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.680 0.320 0.000
I95.8 Other hypotension
0.679 0.321 0.000
I95.0 Idiopathic hypotension
0.679 0.321 0.000
I86 Varicose veins of other sites
0.679 0.321 0.000
R63.0 Anorexia
0.679 0.321 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.678 0.322 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.677 0.323 0.000
G90 Disorders of autonomic nervous system
0.677 0.323 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.677 0.323 0.000
G92 Toxic encephalopathy
0.677 0.323 0.000
M70.6 Trochanteric bursitis
0.676 0.323 0.000
T90 Sequelae of injuries of head
0.676 0.324 0.000
R36 Urethral discharge
0.676 0.324 0.000
R34 Anuria and oliguria
0.676 0.324 0.000
M15-M19 Arthrosis
0.676 0.324 0.000
I49 Other cardiac arrhythmias
0.673 0.327 0.000
F99-F99 Unspecified mental disorder
0.672 0.328 0.000
H40 Glaucoma
0.672 0.328 0.000
M72 Fibroblastic disorders
0.672 0.328 0.000
S05 Injury of eye and orbit
0.672 0.328 0.000
S72.1 Pertrochanteric fracture
0.671 0.329 0.000
G91.1 Obstructive hydrocephalus
0.670 0.329 0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes
0.670 0.330 0.000
Q60-Q64 Congenital malformations of the urinary system
0.669 0.330 0.000
S92.0 Fracture of calcaneus
0.669 0.331 0.000
R15 Faecal incontinence
0.668 0.332 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.668 0.332 0.000
M47.26 Other spondylosis with radiculopathy (Lumbar region)
0.668 0.332 0.000
G43.8 Other migraine
0.667 0.332 0.000
G43.3 Complicated migraine
0.667 0.332 0.000
G43.2 Status migrainosus
0.667 0.332 0.000
G43.1 Migraine with aura [classical migraine]
0.667 0.332 0.000
G43.0 Migraine without aura [common migraine]
0.667 0.332 0.000
H93 Other disorders of ear, not elsewhere classified
0.667 0.333 0.000
R50.0 Fever with chills
0.667 0.333 0.000
I51 Complications and ill-defined descriptions of heart disease
0.667 0.333 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.667 0.333 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.667 0.333 0.000
Q35-Q37 Cleft lip and cleft palate
0.667 0.333 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.667 0.333 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.667 0.333 0.000
Q00-Q07 Congenital malformations of the nervous system
0.667 0.333 0.000
V20-V29 Motorcycle rider injured in transport accident
0.664 0.336 0.000
M79.9 Soft tissue disorder, unspecified
0.663 0.336 0.000
M79.5 Residual foreign body in soft tissue
0.663 0.336 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.663 0.336 0.000
M79.3 Panniculitis, unspecified
0.663 0.336 0.000
M79.2 Neuralgia and neuritis, unspecified
0.663 0.336 0.000
Y40 Systemic antibiotics
0.663 0.336 0.000
G40.9 Epilepsy, unspecified
0.663 0.337 0.000
B34 Viral infection of unspecified site
0.663 0.337 0.000
R04 Haemorrhage from respiratory passages
0.663 0.337 0.000
M41 Scoliosis
0.663 0.337 0.000
M79.85 Other specified soft tissue disorders (Pelvic region and thigh)
0.663 0.337 0.000
H90 Conductive and sensorineural hearing loss
0.662 0.338 0.000
H55-H59 Other disorders of eye and adnexa
0.662 0.338 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.662 0.338 0.000
Chapter II Neoplasms
0.661 0.339 0.000
A41.9 Septicaemia, unspecified
0.660 0.340 0.000
B99-B99 Other infectious diseases
0.660 0.340 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.660 0.340 0.000
B65-B83 Helminthiases
0.660 0.340 0.000
B50-B64 Protozoal diseases
0.660 0.340 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.660 0.340 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.660 0.340 0.000
A80-A89 Viral infections of the central nervous system
0.660 0.340 0.000
A75-A79 Rickettsioses
0.660 0.340 0.000
A70-A74 Other diseases caused by chlamydiae
0.660 0.340 0.000
A65-A69 Other spirochaetal diseases
0.660 0.340 0.000
A20-A28 Certain zoonotic bacterial diseases
0.660 0.340 0.000
A15-A19 Tuberculosis
0.660 0.340 0.000
R42 Dizziness and giddiness
0.660 0.340 0.000
G30-G32 Other degenerative diseases of the nervous system
0.659 0.341 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.659 0.341 0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.658 0.342 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.658 0.342 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.658 0.342 0.000
T42.3 Barbiturates
0.658 0.342 0.000
T42.2 Succinimides and oxazolidinediones
0.658 0.342 0.000
T42.1 Iminostilbenes
0.658 0.342 0.000
T42.0 Hydantoin derivatives
0.658 0.342 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.658 0.342 0.000
M47.92 Spondylosis, unspecified (Cervical region)
0.657 0.342 0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]
0.657 0.343 0.000
T40.8 Lysergide [LSD]
0.657 0.343 0.000
T40.7 Cannabis (derivatives)
0.657 0.343 0.000
T40.5 Cocaine
0.657 0.343 0.000
T40.3 Methadone
0.657 0.343 0.000
T40.1 Heroin
0.657 0.343 0.000
T40.0 Opium
0.657 0.343 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.657 0.343 0.000
H65.9 Nonsuppurative otitis media, unspecified
0.657 0.343 0.000
R47 Speech disturbances, not elsewhere classified
0.656 0.343 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.655 0.345 0.000
R92 Abnormal findings on diagnostic imaging of breast
0.654 0.346 0.000
M24 Other specific joint derangements
0.654 0.346 0.000
G20-G26 Extrapyramidal and movement disorders
0.654 0.346 0.000
F32.3 Severe depressive episode with psychotic symptoms
0.652 0.348 0.000
V18.0 Driver injured in nontraffic accident
0.651 0.349 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.651 0.349 0.000
S81 Open wound of lower leg
0.651 0.349 0.000
R07.2 Precordial pain
0.650 0.350 0.000
S01.5 Open wound of lip and oral cavity
0.650 0.350 0.000
H65.3 Chronic mucoid otitis media
0.650 0.350 0.000
G45.3 Amaurosis fugax
0.650 0.350 0.000
M79.80 Other specified soft tissue disorders (Multiple sites)
0.649 0.351 0.000
T75 Effects of other external causes
0.648 0.351 0.000
T74 Maltreatment syndromes
0.648 0.351 0.000
T73 Effects of other deprivation
0.648 0.351 0.000
T70 Effects of air pressure and water pressure
0.648 0.351 0.000
T69 Other effects of reduced temperature
0.648 0.351 0.000
T67 Effects of heat and light
0.648 0.351 0.000
T71 Asphyxiation
0.648 0.351 0.000
T66 Unspecified effects of radiation
0.648 0.351 0.000
G97.8 Other postprocedural disorders of nervous system
0.648 0.352 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.648 0.352 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.648 0.352 0.000
T39.4 Antirheumatics, not elsewhere classified
0.648 0.352 0.000
T39.2 Pyrazolone derivatives
0.648 0.352 0.000
M47.1 Other spondylosis with myelopathy
0.647 0.353 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.647 0.353 0.000
R23.3 Spontaneous ecchymoses
0.646 0.354 0.000
T92 Sequelae of injuries of upper limb
0.646 0.354 0.000
R68 Other general symptoms and signs
0.646 0.354 0.000
T43.2 Other and unspecified antidepressants
0.646 0.354 0.000
H10-H13 Disorders of conjunctiva
0.645 0.354 0.000
S82.80 Fractures of other parts of lower leg (closed)
0.645 0.355 0.000
R20.2 Paraesthesia of skin
0.645 0.355 0.000
I82 Other venous embolism and thrombosis
0.644 0.356 0.000
S08 Traumatic amputation of part of head
0.643 0.356 0.000
S07 Crushing injury of head
0.643 0.356 0.000
S04 Injury of cranial nerves
0.643 0.356 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.643 0.356 0.000
I95.2 Hypotension due to drugs
0.643 0.357 0.000
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.643 0.357 0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.643 0.357 0.000
M45.X6 Ankylosing spondylitis (Lumbar region)
0.643 0.357 0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.643 0.357 0.000
M45.X4 Ankylosing spondylitis (Thoracic region)
0.643 0.357 0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.643 0.357 0.000
M45.X2 Ankylosing spondylitis (Cervical region)
0.643 0.357 0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.643 0.357 0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.643 0.357 0.000
M65 Synovitis and tenosynovitis
0.642 0.358 0.000
G45.2 Multiple and bilateral precerebral artery syndromes
0.641 0.359 0.000
G45.1 Carotid artery syndrome (hemispheric)
0.641 0.359 0.000
G45.0 Vertebro-basilar artery syndrome
0.641 0.359 0.000
T78.0 Anaphylactic shock due to adverse food reaction
0.641 0.359 0.000
S00 Superficial injury of head
0.641 0.359 0.000
M84 Disorders of continuity of bone
0.640 0.360 0.000
S88 Traumatic amputation of lower leg
0.640 0.360 0.000
S87 Crushing injury of lower leg
0.640 0.360 0.000
S86 Injury of muscle and tendon at lower leg level
0.640 0.360 0.000
S85 Injury of blood vessels at lower leg level
0.640 0.360 0.000
S84 Injury of nerves at lower leg level
0.640 0.360 0.000
R09.0 Asphyxia
0.640 0.360 0.000
S01.1 Open wound of eyelid and periocular area
0.640 0.360 0.000
T51.0 Ethanol
0.639 0.361 0.000
Q21.1 Atrial septal defect
0.639 0.361 0.000
T78.1 Other adverse food reactions, not elsewhere classified
0.638 0.362 0.000
R94.4 Abnormal results of kidney function studies
0.638 0.362 0.000
R27 Other lack of coordination
0.638 0.362 0.000
M21.07 Valgus deformity, not elsewhere classified (Ankle and foot)
0.638 0.362 0.000
T91 Sequelae of injuries of neck and trunk
0.637 0.363 0.000
M46 Other inflammatory spondylopathies
0.637 0.363 0.000
E20-E35 Disorders of other endocrine glands
0.637 0.363 0.000
M43 Other deforming dorsopathies
0.636 0.364 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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