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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs111720385
log Bayes Factor = 5.32077
Chromosome 18   position 43,373,121  (GRCh37) Explore rs111720385 on Ensembl!
Variant rs111720385 is part of Cluster X0079

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XX External causes of morbidity and mortality
0.999 0.001 0.000
Chapter II Neoplasms
0.999 0.001 0.000
C15-C26 Malignant neoplasms of digestive organs
0.997 0.003 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.997 0.003 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.996 0.004 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.995 0.005 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.995 0.005 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.994 0.006 0.000
D70 Agranulocytosis
0.994 0.006 0.000
Y43 Primarily systemic agents
0.993 0.007 0.000
S60-S69 Injuries to the wrist and hand
0.993 0.007 0.000
Y43.3 Other antineoplastic drugs
0.990 0.010 0.000
C91 Lymphoid leukaemia
0.977 0.023 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.970 0.030 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.969 0.031 0.000
T66-T78 Other and unspecified effects of external causes
0.954 0.046 0.000
Chapter VI Diseases of the nervous system
0.946 0.054 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.945 0.055 0.000
S68 Traumatic amputation of wrist and hand
0.940 0.060 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.926 0.074 0.000
W20-W49 Exposure to inanimate mechanical forces
0.925 0.075 0.000
C91.1 Chronic lymphocytic leukaemia
0.924 0.076 0.000
G90-G99 Other disorders of the nervous system
0.921 0.079 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.918 0.082 0.000
T51 Toxic effect of alcohol
0.912 0.088 0.000
G40-G47 Episodic and paroxysmal disorders
0.912 0.088 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.911 0.089 0.000
C20 Malignant neoplasm of rectum
0.911 0.089 0.000
T78 Adverse effects, not elsewhere classified
0.909 0.091 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.908 0.092 0.000
T39.1 4-Aminophenol derivatives
0.905 0.095 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.899 0.101 0.000
Chapter I Certain infectious and parasitic diseases
0.893 0.107 0.000
T51.0 Ethanol
0.889 0.111 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.888 0.112 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.886 0.114 0.000
C81 Hodgkin's disease
0.886 0.114 0.000
G40 Epilepsy
0.877 0.123 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.876 0.124 0.000
A30-A49 Other bacterial diseases
0.869 0.131 0.000
Chapter VIII Diseases of the ear and mastoid process
0.868 0.132 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.866 0.134 0.000
S68.1 Traumatic amputation of other single finger (complete)(partial)
0.864 0.136 0.000
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level
0.862 0.138 0.000
C92 Myeloid leukaemia
0.858 0.142 0.000
S60 Superficial injury of wrist and hand
0.853 0.147 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.852 0.148 0.000
V20-V29 Motorcycle rider injured in transport accident
0.852 0.148 0.000
A41 Other septicaemia
0.849 0.151 0.000
T14 Injury of unspecified body region
0.848 0.152 0.000
Y52 Agents primarily affecting the cardiovascular system
0.847 0.153 0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified
0.842 0.158 0.000
T39.0 Salicylates
0.839 0.161 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.839 0.161 0.000
C15 Malignant neoplasm of oesophagus
0.838 0.162 0.000
Chapter XXII Codes for special purposes
0.838 0.162 0.000
X60-X84 Intentional self-harm
0.835 0.165 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.833 0.167 0.000
C91.4 Hairy-cell leukaemia
0.830 0.170 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.829 0.171 0.000
S62 Fracture at wrist and hand level
0.826 0.174 0.000
T78.4 Allergy, unspecified
0.825 0.175 0.000
C34 Malignant neoplasm of bronchus and lung
0.824 0.176 0.000
A41.9 Septicaemia, unspecified
0.819 0.181 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.817 0.183 0.000
C77.3 Axillary and upper limb lymph nodes
0.815 0.185 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.815 0.185 0.000
C91.0 Acute lymphoblastic leukaemia
0.814 0.186 0.000
H65-H75 Diseases of middle ear and mastoid
0.814 0.186 0.000
C80 Malignant neoplasm without specification of site
0.812 0.188 0.000
T40.2 Other opioids
0.810 0.190 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.809 0.191 0.000
G95 Other diseases of spinal cord
0.808 0.192 0.000
C22.1 Intrahepatic bile duct carcinoma
0.808 0.192 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.807 0.193 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.805 0.195 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.805 0.195 0.000
Y43.1 Antineoplastic antimetabolites
0.805 0.195 0.000
T14.0 Superficial injury of unspecified body region
0.803 0.197 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.801 0.199 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.800 0.200 0.000
D55-D59 Haemolytic anaemias
0.798 0.201 0.000
C81.9 Hodgkin's disease, unspecified
0.796 0.204 0.000
Chapter IX Diseases of the circulatory system
0.795 0.205 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.794 0.206 0.000
W22 Striking against or struck by other objects
0.793 0.207 0.000
T78.3 Angioneurotic oedema
0.792 0.208 0.000
C25 Malignant neoplasm of pancreas
0.791 0.209 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.790 0.210 0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)
0.788 0.212 0.000
Y57 Other and unspecified drugs and medicaments
0.786 0.213 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.786 0.214 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.786 0.214 0.000
S68.0 Traumatic amputation of thumb (complete)(partial)
0.783 0.217 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.782 0.218 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.779 0.221 0.000
C16 Malignant neoplasm of stomach
0.778 0.222 0.000
I30-I52 Other forms of heart disease
0.778 0.222 0.000
G90 Disorders of autonomic nervous system
0.778 0.222 0.000
Y43.4 Immunosuppressive agents
0.777 0.223 0.000
C92.0 Acute myeloid leukaemia
0.776 0.224 0.000
V40-V49 Car occupant injured in transport accident
0.776 0.224 0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts
0.771 0.229 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.770 0.230 0.000
C91.9 Lymphoid leukaemia, unspecified
0.769 0.231 0.000
G43 Migraine
0.769 0.231 0.000
G91 Hydrocephalus
0.769 0.231 0.000
C17 Malignant neoplasm of small intestine
0.767 0.233 0.000
S66.8 Injury of other muscles and tendons at wrist and hand level
0.767 0.233 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.766 0.234 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.765 0.235 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.762 0.238 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.760 0.239 0.000
H71 Cholesteatoma of middle ear
0.759 0.241 0.000
A41.1 Septicaemia due to other specified staphylococcus
0.757 0.243 0.000
G40.8 Other epilepsy
0.753 0.247 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.753 0.247 0.000
S66.7 Injury of multiple extensor muscles and tendons at wrist and hand level
0.753 0.247 0.000
D00-D09 In situ neoplasms
0.753 0.247 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.753 0.247 0.000
D73 Diseases of spleen
0.751 0.249 0.000
I51 Complications and ill-defined descriptions of heart disease
0.751 0.249 0.000
B95-B98 Bacterial, viral and other infectious agents
0.749 0.251 0.000
W50-W64 Exposure to animate mechanical forces
0.749 0.251 0.000
S40-S49 Injuries to the shoulder and upper arm
0.749 0.251 0.000
C23 Malignant neoplasm of gallbladder
0.748 0.252 0.000
C34.9 Bronchus or lung, unspecified
0.747 0.253 0.000
W27 Contact with nonpowered hand tool
0.747 0.253 0.000
D80-D89 Certain disorders involving the immune mechanism
0.746 0.254 0.000
V23 Motorcycle rider injured in collision with car, pick-up truck or van
0.746 0.254 0.000
W00-W19 Falls
0.743 0.257 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.742 0.258 0.000
S67 Crushing injury of wrist and hand
0.742 0.258 0.000
G40.9 Epilepsy, unspecified
0.739 0.261 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.737 0.263 0.000
D75 Other diseases of blood and blood-forming organs
0.734 0.266 0.000
C80.9 Malignant neoplasm, unspecified
0.733 0.267 0.000
T56 Toxic effect of metals
0.730 0.270 0.000
Y52.7 Peripheral vasodilators
0.730 0.270 0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified
0.726 0.274 0.000
Y00-Y09 Assault
0.726 0.274 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.725 0.275 0.000
S80-S89 Injuries to the knee and lower leg
0.724 0.276 0.000
W29 Contact with other powered hand tools and household machinery
0.724 0.276 0.000
S60.8 Other superficial injuries of wrist and hand
0.724 0.276 0.000
T68 Hypothermia
0.724 0.276 0.000
T75 Effects of other external causes
0.721 0.279 0.000
G99.2 Myelopathy in diseases classified elsewhere
0.720 0.280 0.000
A40 Streptococcal septicaemia
0.720 0.280 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.719 0.281 0.000
C77.1 Intrathoracic lymph nodes
0.719 0.281 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.718 0.282 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
S65 Injury of blood vessels at wrist and hand level
0.717 0.283 0.000
Y35-Y36 Legal intervention and operations of war
0.716 0.283 0.000
Y10-Y34 Event of undetermined intent
0.716 0.283 0.000
X85-X99 Assault
0.716 0.283 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.716 0.283 0.000
X30-X39 Exposure to forces of nature
0.716 0.283 0.000
X20-X29 Contact with venomous animals and plants
0.716 0.283 0.000
X10-X19 Contact with heat and hot substances
0.716 0.283 0.000
X00-X09 Exposure to smoke, fire and flames
0.716 0.283 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.716 0.283 0.000
W75-W84 Other accidental threats to breathing
0.716 0.283 0.000
W65-W74 Accidental drowning and submersion
0.716 0.283 0.000
V98-V99 Other and unspecified transport accidents
0.716 0.283 0.000
V95-V97 Air and space transport accidents
0.716 0.283 0.000
V90-V94 Water transport accidents
0.716 0.283 0.000
V70-V79 Bus occupant injured in transport accident
0.716 0.283 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.716 0.283 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.716 0.283 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.716 0.283 0.000
V01-V09 Pedestrian injured in transport accident
0.716 0.283 0.000
S68.2 Traumatic amputation of two or more fingers alone (complete)(partial)
0.716 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.716 0.284 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.715 0.285 0.000
C90.2 Plasmacytoma, extramedullary
0.715 0.285 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.715 0.285 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.715 0.285 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.715 0.285 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.715 0.285 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.715 0.285 0.000
T36 Poisoning by systemic antibiotics
0.715 0.285 0.000
T85.9 Unspecified complication of internal prosthetic device, implant and graft
0.714 0.285 0.000
W49 Exposure to other and unspecified inanimate mechanical forces
0.714 0.286 0.000
Y59 Other and unspecified vaccines and biological substances
0.714 0.286 0.000
Y58 Bacterial vaccines
0.714 0.286 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.714 0.286 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.714 0.286 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.714 0.286 0.000
Y48 Anaesthetics and therapeutic gases
0.714 0.286 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.714 0.286 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.714 0.286 0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.714 0.286 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.713 0.287 0.000
C95 Leukaemia of unspecified cell type
0.713 0.287 0.000
C94 Other leukaemias of specified cell type
0.713 0.287 0.000
C93 Monocytic leukaemia
0.713 0.287 0.000
C86 Other specified types of T/NK-cell lymphoma
0.713 0.287 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.713 0.287 0.000
G41 Status epilepticus
0.713 0.287 0.000
D74 Methaemoglobinaemia
0.713 0.287 0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.713 0.287 0.000
D71 Functional disorders of polymorphonuclear neutrophils
0.713 0.287 0.000
Y43.9 Primarily systemic agent, unspecified
0.712 0.288 0.000
Y43.8 Other primarily systemic agents, not elsewhere classified
0.712 0.288 0.000
Y43.6 Enzymes, not elsewhere classified
0.712 0.288 0.000
Y43.5 Acidifying and alkalising agents
0.712 0.288 0.000
Y43.2 Antineoplastic natural products
0.712 0.288 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.712 0.288 0.000
I34 Nonrheumatic mitral valve disorders
0.712 0.288 0.000
C22.0 Liver cell carcinoma
0.711 0.289 0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft
0.711 0.289 0.000
X50-X57 Overexertion, travel and privation
0.711 0.289 0.000
A41.0 Septicaemia due to Staphylococcus aureus
0.708 0.292 0.000
Y43.0 Antiallergic and antiemetic drugs
0.707 0.293 0.000
H60-H62 Diseases of external ear
0.707 0.293 0.000
I51.7 Cardiomegaly
0.707 0.293 0.000
C77.9 Lymph node, unspecified
0.706 0.294 0.000
H73 Other disorders of tympanic membrane
0.706 0.294 0.000
G44 Other headache syndromes
0.705 0.295 0.000
S69 Other and unspecified injuries of wrist and hand
0.703 0.297 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.701 0.298 0.000
C91.8 Mature B-cell leukaemia Burkitt-type
0.701 0.299 0.000
C91.7 Other lymphoid leukaemia
0.701 0.299 0.000
C91.6 Prolymphocytic leukaemia of T-cell type
0.701 0.299 0.000
C91.5 Adult T-cell leukaemia
0.701 0.299 0.000
C91.3 Prolymphocytic leukaemia
0.701 0.299 0.000
C91.2 Subacute lymphocytic leukaemia
0.701 0.299 0.000
W20 Struck by thrown, projected or falling object
0.701 0.299 0.000
C88 Malignant immunoproliferative diseases
0.700 0.300 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.700 0.300 0.000
W22.9 Unspecified place
0.699 0.301 0.000
S62.4 Multiple fractures of metacarpal bones
0.698 0.302 0.000
T78.1 Other adverse food reactions, not elsewhere classified
0.698 0.302 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.697 0.303 0.000
I49 Other cardiac arrhythmias
0.696 0.304 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.695 0.305 0.000
T39.4 Antirheumatics, not elsewhere classified
0.695 0.305 0.000
T39.2 Pyrazolone derivatives
0.695 0.305 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.694 0.306 0.000
T82.1 Mechanical complication of cardiac electronic device
0.694 0.306 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.694 0.306 0.000
Y42.5 Other oestrogens and progestogens
0.692 0.308 0.000
I35 Nonrheumatic aortic valve disorders
0.692 0.308 0.000
B15-B19 Viral hepatitis
0.692 0.308 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.691 0.309 0.000
G43.1 Migraine with aura [classical migraine]
0.689 0.311 0.000
C77.0 Lymph nodes of head, face and neck
0.686 0.314 0.000
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.685 0.315 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.685 0.315 0.000
T74 Maltreatment syndromes
0.684 0.316 0.000
T73 Effects of other deprivation
0.684 0.316 0.000
T70 Effects of air pressure and water pressure
0.684 0.316 0.000
T69 Other effects of reduced temperature
0.684 0.316 0.000
T67 Effects of heat and light
0.684 0.316 0.000
T71 Asphyxiation
0.684 0.316 0.000
T66 Unspecified effects of radiation
0.684 0.316 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.683 0.317 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.683 0.317 0.000
G40.5 Special epileptic syndromes
0.682 0.318 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.682 0.318 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.681 0.319 0.000
V10-V19 Pedal cyclist injured in transport accident
0.680 0.320 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.680 0.320 0.000
T85.1 Mechanical complication of implanted electronic stimulator of nervous system
0.679 0.321 0.000
C34.0 Main bronchus
0.678 0.321 0.000
A65-A69 Other spirochaetal diseases
0.678 0.322 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.678 0.322 0.000
T65 Toxic effect of other and unspecified substances
0.677 0.322 0.000
T62 Toxic effect of other noxious substances eaten as food
0.677 0.322 0.000
T61 Toxic effect of noxious substances eaten as seafood
0.677 0.322 0.000
T60 Toxic effect of pesticides
0.677 0.322 0.000
T57 Toxic effect of other inorganic substances
0.677 0.322 0.000
T54 Toxic effect of corrosive substances
0.677 0.322 0.000
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone
0.677 0.322 0.000
T52 Toxic effect of organic solvents
0.677 0.322 0.000
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants
0.677 0.322 0.000
T58 Toxic effect of carbon monoxide
0.677 0.322 0.000
T55 Toxic effect of soaps and detergents
0.677 0.322 0.000
V80-V89 Other land transport accidents
0.677 0.323 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.675 0.325 0.000
T86 Failure and rejection of transplanted organs and tissues
0.674 0.326 0.000
S68.9 Traumatic amputation of wrist and hand, level unspecified
0.674 0.326 0.000
S68.8 Traumatic amputation of other parts of wrist and hand
0.674 0.326 0.000
S68.4 Traumatic amputation of hand at wrist level
0.674 0.326 0.000
S68.3 Combined traumatic amputation of (part of) finger(s) with other parts of wrist and hand
0.674 0.326 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.674 0.326 0.000
G95.1 Vascular myelopathies
0.674 0.326 0.000
C15.9 Oesophagus, unspecified
0.671 0.329 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.671 0.329 0.000
V23.4 Driver injured in traffic accident
0.670 0.330 0.000
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified
0.669 0.331 0.000
C16.0 Cardia
0.668 0.332 0.000
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified
0.668 0.332 0.000
C81.1 Nodular sclerosis
0.667 0.332 0.000
C26.0 Intestinal tract, part unspecified
0.667 0.333 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.667 0.333 0.000
I33 Acute and subacute endocarditis
0.665 0.335 0.000
I27 Other pulmonary heart diseases
0.665 0.335 0.000
D72 Other disorders of white blood cells
0.664 0.335 0.000
S66.9 Injury of unspecified muscle and tendon at wrist and hand level
0.664 0.336 0.000
S66.6 Injury of multiple flexor muscles and tendons at wrist and hand level
0.664 0.336 0.000
S66.5 Injury of intrinsic muscle and tendon of other finger at wrist and hand level
0.664 0.336 0.000
S66.4 Injury of intrinsic muscle and tendon of thumb at wrist and hand level
0.664 0.336 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.664 0.336 0.000
B50-B64 Protozoal diseases
0.664 0.336 0.000
W46 Contact with hypodermic needle
0.663 0.337 0.000
W45 Foreign body or object entering through skin
0.663 0.337 0.000
W43 Exposure to vibration
0.663 0.337 0.000
W42 Exposure to noise
0.663 0.337 0.000
W41 Exposure to high-pressure jet
0.663 0.337 0.000
W40 Explosion of other materials
0.663 0.337 0.000
W39 Discharge of firework
0.663 0.337 0.000
W38 Explosion and rupture of other specified pressurised devices
0.663 0.337 0.000
W37 Explosion and rupture of pressurised tyre, pipe or hose
0.663 0.337 0.000
W36 Explosion and rupture of gas cylinder
0.663 0.337 0.000
W35 Explosion and rupture of boiler
0.663 0.337 0.000
W34 Discharge from other and unspecified firearms
0.663 0.337 0.000
W33 Rifle, shotgun and larger firearm discharge
0.663 0.337 0.000
W32 Handgun discharge
0.663 0.337 0.000
W31 Contact with other and unspecified machinery
0.663 0.337 0.000
W30 Contact with agricultural machinery
0.663 0.337 0.000
W28 Contact with powered lawn mower
0.663 0.337 0.000
W26 Contact with knife, sword or dagger
0.663 0.337 0.000
W24 Contact with lifting and transmission devices, not elsewhere classified
0.663 0.337 0.000
W23 Caught, crushed, jammed or pinched in or between objects
0.663 0.337 0.000
W21 Striking against or struck by sports equipment
0.663 0.337 0.000
C01 Malignant neoplasm of base of tongue
0.663 0.337 0.000
G95.9 Disease of spinal cord, unspecified
0.663 0.337 0.000
T87 Complications peculiar to reattachment and amputation
0.662 0.337 0.000
Y52.4 Angiotensin-converting-enzyme inhibitors
0.662 0.337 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.662 0.338 0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters
0.660 0.340 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.660 0.340 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.660 0.340 0.000
G92 Toxic encephalopathy
0.660 0.340 0.000
T51.9 Alcohol, unspecified
0.660 0.340 0.000
W44 Foreign body entering into or through eye or natural orifice
0.659 0.341 0.000
C32 Malignant neoplasm of larynx
0.659 0.341 0.000
G90.0 Idiopathic peripheral autonomic neuropathy
0.658 0.341 0.000
Q50-Q56 Congenital malformations of genital organs
0.658 0.342 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.658 0.342 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.657 0.343 0.000
G47 Sleep disorders
0.657 0.343 0.000
X68 Intentional self-poisoning by and exposure to pesticides
0.657 0.343 0.000
C15.5 Lower third of oesophagus
0.656 0.344 0.000
S60.2 Contusion of other parts of wrist and hand
0.655 0.345 0.000
T51.8 Other alcohols
0.654 0.346 0.000
T51.3 Fusel oil
0.654 0.346 0.000
T51.2 2-Propanol
0.654 0.346 0.000
T51.1 Methanol
0.654 0.346 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.654 0.346 0.000
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract
0.654 0.346 0.000
T13 Other injuries of lower limb, level unspecified
0.653 0.346 0.000
T11 Other injuries of upper limb, level unspecified
0.653 0.346 0.000
T09 Other injuries of spine and trunk, level unspecified
0.653 0.346 0.000
T12.X1 Fracture of lower limb, level unspecified (open)
0.653 0.346 0.000
T12.X0 Fracture of lower limb, level unspecified (closed)
0.653 0.346 0.000
T12 Fracture of lower limb, level unspecified
0.653 0.346 0.000
T10.X1 Fracture of upper limb, level unspecified (open)
0.653 0.346 0.000
T10.X0 Fracture of upper limb, level unspecified (closed)
0.653 0.346 0.000
T10 Fracture of upper limb, level unspecified
0.653 0.346 0.000
T08.X1 Fracture of spine, level unspecified (open)
0.653 0.346 0.000
T08.X0 Fracture of spine, level unspecified (closed)
0.653 0.346 0.000
T08 Fracture of spine, level unspecified
0.653 0.346 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.653 0.347 0.000
D73.5 Infarction of spleen
0.652 0.348 0.000
T78.9 Adverse effect, unspecified
0.651 0.348 0.000
T78.8 Other adverse effects, not elsewhere classified
0.651 0.348 0.000
T78.0 Anaphylactic shock due to adverse food reaction
0.651 0.348 0.000
G70-G73 Diseases of myoneural junction and muscle
0.651 0.348 0.000
C25.1 Body of pancreas
0.651 0.349 0.000
Y57.9 Drug or medicament, unspecified
0.650 0.350 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.650 0.350 0.000
S63.5 Sprain and strain of wrist
0.650 0.350 0.000
G30-G32 Other degenerative diseases of the nervous system
0.649 0.351 0.000
X63 Intentional self-poisoning by and exposure to other drugs acting on the autonomic nervous system
0.649 0.351 0.000
Y44 Agents primarily affecting blood constituents
0.646 0.354 0.000
S62.7 Multiple fractures of fingers
0.645 0.355 0.000
T78.2 Anaphylactic shock, unspecified
0.645 0.355 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.645 0.355 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.645 0.355 0.000
C31 Malignant neoplasm of accessory sinuses
0.645 0.355 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.645 0.355 0.000
C37 Malignant neoplasm of thymus
0.645 0.355 0.000
C33 Malignant neoplasm of trachea
0.645 0.355 0.000
D58 Other hereditary haemolytic anaemias
0.644 0.356 0.000
Y40 Systemic antibiotics
0.643 0.357 0.000
T59 Toxic effect of other gases, fumes and vapours
0.642 0.358 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.641 0.359 0.000
C83.3 Large cell (diffuse)
0.641 0.359 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.640 0.360 0.000
B65-B83 Helminthiases
0.640 0.360 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.640 0.360 0.000
A75-A79 Rickettsioses
0.640 0.360 0.000
A70-A74 Other diseases caused by chlamydiae
0.640 0.360 0.000
A20-A28 Certain zoonotic bacterial diseases
0.640 0.360 0.000
A15-A19 Tuberculosis
0.640 0.360 0.000
I49.3 Ventricular premature depolarisation
0.640 0.360 0.000
W25 Contact with sharp glass
0.640 0.360 0.000
S70-S79 Injuries to the hip and thigh
0.638 0.362 0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes
0.638 0.362 0.000
H70 Mastoiditis and related conditions
0.638 0.362 0.000
C22.7 Other specified carcinomas of liver
0.637 0.363 0.000
C22.4 Other sarcomas of liver
0.637 0.363 0.000
C22.3 Angiosarcoma of liver
0.637 0.363 0.000
C22.2 Hepatoblastoma
0.637 0.363 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.637 0.363 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.636 0.364 0.000
G96 Other disorders of central nervous system
0.636 0.364 0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]
0.635 0.365 0.000
T40.8 Lysergide [LSD]
0.635 0.365 0.000
T40.7 Cannabis (derivatives)
0.635 0.365 0.000
T40.6 Other and unspecified narcotics
0.635 0.365 0.000
T40.5 Cocaine
0.635 0.365 0.000
T40.3 Methadone
0.635 0.365 0.000
T40.1 Heroin
0.635 0.365 0.000
T40.0 Opium
0.635 0.365 0.000
C81.7 Other Hodgkin's disease
0.635 0.365 0.000
C81.4 Lymphocyte-rich classical Hodgkin lymphoma
0.635 0.365 0.000
C81.3 Lymphocytic depletion
0.635 0.365 0.000
C81.2 Mixed cellularity
0.635 0.365 0.000
C81.0 Lymphocytic predominance
0.635 0.365 0.000
T20 Burn and corrosion of head and neck
0.634 0.366 0.000
T85.2 Mechanical complication of intraocular lens
0.634 0.366 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.633 0.367 0.000
Y42.0 Glucocorticoids and synthetic analogs
0.632 0.368 0.000
I34.1 Mitral (valve) prolapse
0.632 0.368 0.000
G99.0 Autonomic neuropathy in endocrine and metabolic diseases
0.630 0.370 0.000
G40.7 Petit mal, unspecified, without grand mal seizures
0.629 0.371 0.000
G40.4 Other generalised epilepsy and epileptic syndromes
0.629 0.371 0.000
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset
0.629 0.371 0.000
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt
0.628 0.372 0.000
H73.8 Other specified disorders of tympanic membrane
0.628 0.372 0.000
X41 Accidental poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified
0.627 0.372 0.000
S10-S19 Injuries to the neck
0.627 0.373 0.000
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level
0.627 0.373 0.000
Y54.3 Benzothiadiazine derivatives
0.627 0.373 0.000
C15.4 Middle third of oesophagus
0.627 0.373 0.000
S63.3 Traumatic rupture of ligament of wrist and carpus
0.625 0.375 0.000
T40.4 Other synthetic narcotics
0.625 0.375 0.000
S62.8 Fracture of other and unspecified parts of wrist and hand
0.625 0.375 0.000
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract
0.623 0.377 0.000
A44 Bartonellosis
0.623 0.377 0.000
A43 Nocardiosis
0.623 0.377 0.000
A42 Actinomycosis
0.623 0.377 0.000
A39 Meningococcal infection
0.623 0.377 0.000
A37 Whooping cough
0.623 0.377 0.000
A36 Diphtheria
0.623 0.377 0.000
A32 Listeriosis
0.623 0.377 0.000
A31 Infection due to other mycobacteria
0.623 0.377 0.000
A30 Leprosy [Hansen's disease]
0.623 0.377 0.000
A38 Scarlet fever
0.623 0.377 0.000
A35 Other tetanus
0.623 0.377 0.000
A34 Obstetrical tetanus
0.623 0.377 0.000
A33 Tetanus neonatorum
0.623 0.377 0.000
S60.9 Superficial injury of wrist and hand, unspecified
0.623 0.377 0.000
A48 Other bacterial diseases, not elsewhere classified
0.622 0.377 0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
0.622 0.378 0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis
0.621 0.379 0.000
T82.4 Mechanical complication of vascular dialysis catheter
0.621 0.379 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.619 0.381 0.000
G91.1 Obstructive hydrocephalus
0.619 0.381 0.000
A49 Bacterial infection of unspecified site
0.619 0.381 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.619 0.381 0.000
W27.6 Industrial and construction area
0.619 0.381 0.000
A80-A89 Viral infections of the central nervous system
0.618 0.382 0.000
B99-B99 Other infectious diseases
0.618 0.382 0.000
G97.0 Cerebrospinal fluid leak from spinal puncture
0.617 0.383 0.000
I26 Pulmonary embolism
0.617 0.383 0.000
C92.9 Myeloid leukaemia, unspecified
0.615 0.384 0.000
C92.8 Acute myeloid leukaemia with multilineage dysplasia
0.615 0.384 0.000
C92.7 Other myeloid leukaemia
0.615 0.384 0.000
C92.6 Acute myeloid leukaemia with 11q23-abnormality
0.615 0.384 0.000
C92.5 Acute myelomonocytic leukaemia
0.615 0.384 0.000
C92.4 Acute promyelocytic leukaemia
0.615 0.384 0.000
C92.3 Myeloid sarcoma
0.615 0.384 0.000
C92.2 Subacute myeloid leukaemia
0.615 0.384 0.000
C25.9 Pancreas, unspecified
0.615 0.385 0.000
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level
0.615 0.385 0.000
G97.1 Other reaction to spinal and lumbar puncture
0.615 0.385 0.000
Q00-Q07 Congenital malformations of the nervous system
0.614 0.386 0.000
D75.1 Secondary polycythaemia
0.613 0.387 0.000
C21 Malignant neoplasm of anus and anal canal
0.613 0.387 0.000
I51.8 Other ill-defined heart diseases
0.613 0.387 0.000
T79-T79 Certain early complications of trauma
0.612 0.387 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.612 0.388 0.000
S60.7 Multiple superficial injuries of wrist and hand
0.611 0.389 0.000
S60.1 Contusion of finger(s) with damage to nail
0.611 0.389 0.000
S60.0 Contusion of finger(s) without damage to nail
0.611 0.389 0.000
V29 Motorcycle rider injured in other and unspecified transport accidents
0.611 0.389 0.000
V28 Motorcycle rider injured in noncollision transport accident
0.611 0.389 0.000
V27 Motorcycle rider injured in collision with fixed or stationary object
0.611 0.389 0.000
V26 Motorcycle rider injured in collision with other nonmotor vehicle
0.611 0.389 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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