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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs111771141
log Bayes Factor = 14.5556
Chromosome 3   position 6,413,411  (GRCh37) Explore rs111771141 on Ensembl!
Variant rs111771141 is part of Cluster X0043

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter XIV Diseases of the genitourinary system
0.999 0.001 0.000
Chapter X Diseases of the respiratory system
0.999 0.001 0.000
N30-N39 Other diseases of urinary system
0.997 0.003 0.000
Chapter V Mental and behavioural disorders
0.993 0.007 0.000
M20-M25 Other joint disorders
0.992 0.008 0.000
Chapter II Neoplasms
0.991 0.009 0.000
Chapter VI Diseases of the nervous system
0.989 0.011 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.989 0.011 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.989 0.011 0.000
F41 Other anxiety disorders
0.985 0.015 0.000
F41.9 Anxiety disorder, unspecified
0.982 0.018 0.000
J40-J47 Chronic lower respiratory diseases
0.981 0.019 0.000
N60-N64 Disorders of breast
0.969 0.031 0.000
N30 Cystitis
0.962 0.038 0.000
T81 Complications of procedures, not elsewhere classified
0.961 0.039 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.960 0.040 0.000
M25 Other joint disorders, not elsewhere classified
0.952 0.048 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.947 0.053 0.000
J44 Other chronic obstructive pulmonary disease
0.946 0.054 0.000
M23 Internal derangement of knee
0.944 0.056 0.000
M70-M79 Other soft tissue disorders
0.934 0.066 0.000
Chapter VIII Diseases of the ear and mastoid process
0.934 0.066 0.000
J30-J39 Other diseases of upper respiratory tract
0.927 0.073 0.000
C43 Malignant melanoma of skin
0.927 0.073 0.000
S80-S89 Injuries to the knee and lower leg
0.922 0.078 0.000
M50-M54 Other dorsopathies
0.911 0.089 0.000
Chapter VII Diseases of the eye and adnexa
0.909 0.091 0.000
G40-G47 Episodic and paroxysmal disorders
0.908 0.092 0.000
N60 Benign mammary dysplasia
0.903 0.097 0.000
C79 Secondary malignant neoplasm of other sites
0.902 0.098 0.000
N35 Urethral stricture
0.901 0.099 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.897 0.103 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.895 0.105 0.000
T81.4 Infection following a procedure, not elsewhere classified
0.894 0.106 0.000
G90-G99 Other disorders of the nervous system
0.893 0.107 0.000
Chapter XX External causes of morbidity and mortality
0.887 0.113 0.000
J90-J94 Other diseases of pleura
0.884 0.116 0.000
Chapter I Certain infectious and parasitic diseases
0.883 0.117 0.000
N39 Other disorders of urinary system
0.883 0.117 0.000
N30.9 Cystitis, unspecified
0.882 0.118 0.000
H90-H95 Other disorders of ear
0.882 0.118 0.000
S70-S79 Injuries to the hip and thigh
0.881 0.119 0.000
H25-H28 Disorders of lens
0.870 0.130 0.000
J47 Bronchiectasis
0.869 0.131 0.000
N64 Other disorders of breast
0.866 0.134 0.000
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified
0.865 0.135 0.000
E70-E90 Metabolic disorders
0.855 0.145 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.854 0.146 0.000
M54 Dorsalgia
0.854 0.146 0.000
H25 Senile cataract
0.854 0.146 0.000
M45-M49 Spondylopathies
0.853 0.147 0.000
M23.8 Other internal derangements of knee
0.850 0.150 0.000
C64-C68 Malignant neoplasms of urinary tract
0.849 0.151 0.000
M25.5 Pain in joint
0.842 0.158 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.842 0.158 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.840 0.160 0.000
N25-N29 Other disorders of kidney and ureter
0.839 0.161 0.000
Chapter XI Diseases of the digestive system
0.839 0.161 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.836 0.164 0.000
H91 Other hearing loss
0.835 0.165 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.835 0.165 0.000
J95-J99 Other diseases of the respiratory system
0.834 0.166 0.000
N32 Other disorders of bladder
0.833 0.167 0.000
N35.9 Urethral stricture, unspecified
0.833 0.167 0.000
M23.3 Other meniscus derangements
0.832 0.168 0.000
M75 Shoulder lesions
0.830 0.170 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.830 0.170 0.000
K80 Cholelithiasis
0.827 0.173 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.826 0.174 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.824 0.176 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.822 0.178 0.000
N99-N99 Other disorders of the genitourinary system
0.816 0.184 0.000
N36 Other disorders of urethra
0.815 0.185 0.000
M05-M14 Inflammatory polyarthropathies
0.814 0.186 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.814 0.186 0.000
N39.0 Urinary tract infection, site not specified
0.812 0.188 0.000
S00-S09 Injuries to the head
0.811 0.189 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.809 0.191 0.000
C51-C58 Malignant neoplasms of female genital organs
0.809 0.191 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.805 0.195 0.000
N60.1 Diffuse cystic mastopathy
0.804 0.196 0.000
H25.9 Senile cataract, unspecified
0.803 0.197 0.000
H91.9 Hearing loss, unspecified
0.802 0.198 0.000
M25.4 Effusion of joint
0.800 0.200 0.000
N10-N16 Renal tubulo-interstitial diseases
0.799 0.201 0.000
S80 Superficial injury of lower leg
0.798 0.202 0.000
M80-M85 Disorders of bone density and structure
0.798 0.202 0.000
M40-M43 Deforming dorsopathies
0.798 0.202 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.796 0.204 0.000
N30.8 Other cystitis
0.796 0.204 0.000
Chapter XXII Codes for special purposes
0.796 0.204 0.000
H25.1 Senile nuclear cataract
0.795 0.205 0.000
M25.7 Osteophyte
0.794 0.206 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.792 0.208 0.000
C43.7 Malignant melanoma of lower limb, including hip
0.792 0.208 0.000
M31 Other necrotising vasculopathies
0.792 0.208 0.000
M20 Acquired deformities of fingers and toes
0.792 0.208 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.789 0.211 0.000
G30-G32 Other degenerative diseases of the nervous system
0.788 0.212 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.788 0.212 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.788 0.212 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.787 0.213 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.785 0.215 0.000
J43 Emphysema
0.784 0.216 0.000
N60.8 Other benign mammary dysplasias
0.783 0.217 0.000
F40 Phobic anxiety disorders
0.782 0.218 0.000
G20-G26 Extrapyramidal and movement disorders
0.780 0.219 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.780 0.220 0.000
J30 Vasomotor and allergic rhinitis
0.779 0.221 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.778 0.222 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.778 0.222 0.000
M65-M68 Disorders of synovium and tendon
0.777 0.223 0.000
C44 Other malignant neoplasms of skin
0.775 0.225 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.774 0.226 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.773 0.227 0.000
J90 Pleural effusion, not elsewhere classified
0.772 0.228 0.000
J00-J06 Acute upper respiratory infections
0.771 0.229 0.000
K80.1 Calculus of gallbladder with other cholecystitis
0.769 0.231 0.000
F41.0 Panic disorder [episodic paroxysmal anxiety]
0.769 0.231 0.000
S72 Fracture of femur
0.769 0.231 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.768 0.232 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.766 0.234 0.000
N62 Hypertrophy of breast
0.765 0.235 0.000
T86 Failure and rejection of transplanted organs and tissues
0.765 0.235 0.000
S40-S49 Injuries to the shoulder and upper arm
0.765 0.235 0.000
J60-J70 Lung diseases due to external agents
0.765 0.235 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.764 0.236 0.000
N30.3 Trigonitis
0.763 0.237 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.763 0.237 0.000
N30.0 Acute cystitis
0.762 0.238 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.761 0.239 0.000
Chapter IX Diseases of the circulatory system
0.761 0.239 0.000
M00-M03 Infectious arthropathies
0.760 0.240 0.000
N64.8 Other specified disorders of breast
0.760 0.240 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.759 0.241 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.759 0.241 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.758 0.242 0.000
C43.4 Malignant melanoma of scalp and neck
0.758 0.242 0.000
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.756 0.244 0.000
M79.6 Pain in limb
0.755 0.245 0.000
N32.0 Bladder-neck obstruction
0.753 0.247 0.000
A30-A49 Other bacterial diseases
0.752 0.248 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.751 0.249 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.750 0.250 0.000
C43.9 Malignant melanoma of skin, unspecified
0.749 0.251 0.000
R05 Cough
0.749 0.251 0.000
K80.5 Calculus of bile duct without cholangitis or cholecystitis
0.748 0.252 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.748 0.252 0.000
N17-N19 Renal failure
0.747 0.253 0.000
R41.0 Disorientation, unspecified
0.747 0.253 0.000
T81.8 Other complications of procedures, not elsewhere classified
0.747 0.253 0.000
S60-S69 Injuries to the wrist and hand
0.746 0.254 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.744 0.256 0.000
M23.4 Loose body in knee
0.743 0.257 0.000
C43.6 Malignant melanoma of upper limb, including shoulder
0.743 0.257 0.000
M25.56 Pain in joint (Lower leg)
0.742 0.258 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.742 0.258 0.000
J46 Status asthmaticus
0.741 0.258 0.000
S82 Fracture of lower leg, including ankle
0.741 0.259 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.741 0.259 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.741 0.259 0.000
C43.5 Malignant melanoma of trunk
0.740 0.260 0.000
G93 Other disorders of brain
0.739 0.261 0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified
0.736 0.264 0.000
R47-R49 Symptoms and signs involving speech and voice
0.734 0.266 0.000
M54.5 Low back pain
0.734 0.266 0.000
J09-J18 Influenza and pneumonia
0.733 0.267 0.000
R07 Pain in throat and chest
0.732 0.268 0.000
E78.5 Hyperlipidaemia, unspecified
0.729 0.271 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.728 0.272 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.727 0.273 0.000
M86-M90 Other osteopathies
0.726 0.274 0.000
G43 Migraine
0.725 0.275 0.000
J34 Other disorders of nose and nasal sinuses
0.725 0.275 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.724 0.275 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.722 0.278 0.000
S20-S29 Injuries to the thorax
0.722 0.278 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.722 0.278 0.000
C80 Malignant neoplasm without specification of site
0.718 0.282 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
M91-M94 Chondropathies
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
T79-T79 Certain early complications of trauma
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S10-S19 Injuries to the neck
0.717 0.283 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.715 0.285 0.000
A00-A09 Intestinal infectious diseases
0.715 0.285 0.000
N37 Urethral disorders in diseases classified elsewhere
0.715 0.285 0.000
N34 Urethritis and urethral syndrome
0.715 0.285 0.000
N33 Bladder disorders in diseases classified elsewhere
0.715 0.285 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.715 0.285 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.714 0.286 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.714 0.286 0.000
J42 Unspecified chronic bronchitis
0.713 0.286 0.000
C43.3 Malignant melanoma of other and unspecified parts of face
0.713 0.287 0.000
E20-E35 Disorders of other endocrine glands
0.712 0.288 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.712 0.288 0.000
G91 Hydrocephalus
0.712 0.288 0.000
F99-F99 Unspecified mental disorder
0.712 0.288 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.712 0.288 0.000
F80-F89 Disorders of psychological development
0.712 0.288 0.000
F70-F79 Mental retardation
0.712 0.288 0.000
F60-F69 Disorders of adult personality and behaviour
0.712 0.288 0.000
S50-S59 Injuries to the elbow and forearm
0.711 0.288 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.711 0.289 0.000
M34 Systemic sclerosis
0.711 0.289 0.000
M33 Dermatopolymyositis
0.711 0.289 0.000
M32 Systemic lupus erythematosus
0.711 0.289 0.000
M30 Polyarteritis nodosa and related conditions
0.711 0.289 0.000
M21 Other acquired deformities of limbs
0.711 0.289 0.000
N30.2 Other chronic cystitis
0.711 0.289 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.711 0.289 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.711 0.289 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.711 0.289 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.711 0.289 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.711 0.289 0.000
S80.9 Superficial injury of lower leg, unspecified
0.710 0.290 0.000
N63 Unspecified lump in breast
0.709 0.291 0.000
G70-G73 Diseases of myoneural junction and muscle
0.709 0.291 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.709 0.291 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.709 0.291 0.000
F48 Other neurotic disorders
0.709 0.291 0.000
F45 Somatoform disorders
0.709 0.291 0.000
F44 Dissociative [conversion] disorders
0.709 0.291 0.000
F43 Reaction to severe stress, and adjustment disorders
0.709 0.291 0.000
F42 Obsessive-compulsive disorder
0.709 0.291 0.000
T87 Complications peculiar to reattachment and amputation
0.709 0.291 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.709 0.291 0.000
S90-S99 Injuries to the ankle and foot
0.708 0.291 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.708 0.292 0.000
G44 Other headache syndromes
0.707 0.293 0.000
E87.6 Hypokalaemia
0.706 0.294 0.000
F41.8 Other specified anxiety disorders
0.706 0.294 0.000
F41.3 Other mixed anxiety disorders
0.706 0.294 0.000
F41.1 Generalised anxiety disorder
0.706 0.294 0.000
T66-T78 Other and unspecified effects of external causes
0.705 0.294 0.000
G96 Other disorders of central nervous system
0.705 0.295 0.000
M13 Other arthritis
0.704 0.296 0.000
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)
0.703 0.296 0.000
M45 Ankylosing spondylitis
0.703 0.297 0.000
J41 Simple and mucopurulent chronic bronchitis
0.703 0.297 0.000
M75.4 Impingement syndrome of shoulder
0.702 0.298 0.000
J93 Pneumothorax
0.701 0.299 0.000
M54.9 Dorsalgia, unspecified
0.700 0.300 0.000
Y95 Nosocomial condition
0.700 0.300 0.000
N26 Unspecified contracted kidney
0.700 0.300 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.699 0.301 0.000
K80.2 Calculus of gallbladder without cholecystitis
0.698 0.302 0.000
M22 Disorders of patella
0.696 0.304 0.000
N39.9 Disorder of urinary system, unspecified
0.696 0.304 0.000
G95 Other diseases of spinal cord
0.694 0.306 0.000
J39 Other diseases of upper respiratory tract
0.694 0.306 0.000
S79 Other and unspecified injuries of hip and thigh
0.693 0.307 0.000
B35-B49 Mycoses
0.692 0.308 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.692 0.308 0.000
G47 Sleep disorders
0.691 0.308 0.000
E40-E46 Malnutrition
0.691 0.309 0.000
M48 Other spondylopathies
0.691 0.309 0.000
J33 Nasal polyp
0.690 0.310 0.000
N30.4 Irradiation cystitis
0.690 0.310 0.000
N30.1 Interstitial cystitis (chronic)
0.690 0.310 0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts
0.689 0.311 0.000
T81.9 Unspecified complication of procedure
0.689 0.311 0.000
T81.7 Vascular complications following a procedure, not elsewhere classified
0.689 0.311 0.000
T81.6 Acute reaction to foreign substance accidentally left during a procedure
0.689 0.311 0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure
0.689 0.311 0.000
T81.1 Shock during or resulting from a procedure, not elsewhere classified
0.689 0.311 0.000
K80.0 Calculus of gallbladder with acute cholecystitis
0.689 0.311 0.000
S00 Superficial injury of head
0.688 0.312 0.000
N00-N08 Glomerular diseases
0.687 0.312 0.000
F41.2 Mixed anxiety and depressive disorder
0.686 0.314 0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified
0.685 0.315 0.000
K86 Other diseases of pancreas
0.685 0.315 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.684 0.316 0.000
H43-H45 Disorders of vitreous body and globe
0.684 0.316 0.000
H80-H83 Diseases of inner ear
0.683 0.316 0.000
J36 Peritonsillar abscess
0.683 0.316 0.000
M25.9 Joint disorder, unspecified
0.683 0.317 0.000
M25.8 Other specified joint disorders
0.683 0.317 0.000
M25.3 Other instability of joint
0.683 0.317 0.000
M25.2 Flail joint
0.683 0.317 0.000
M25.1 Fistula of joint
0.683 0.317 0.000
M25.0 Haemarthrosis
0.683 0.317 0.000
M24 Other specific joint derangements
0.681 0.318 0.000
C15-C26 Malignant neoplasms of digestive organs
0.681 0.319 0.000
N64.1 Fat necrosis of breast
0.680 0.319 0.000
R07.3 Other chest pain
0.680 0.320 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.680 0.320 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.679 0.321 0.000
C56 Malignant neoplasm of ovary
0.679 0.321 0.000
C34 Malignant neoplasm of bronchus and lung
0.679 0.321 0.000
I20-I25 Ischaemic heart diseases
0.679 0.321 0.000
J40 Bronchitis, not specified as acute or chronic
0.678 0.322 0.000
M23.89 Other internal derangements of knee (Unspecified ligament or Unspecified meniscus)
0.677 0.323 0.000
M23.9 Internal derangement of knee, unspecified
0.677 0.323 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.677 0.323 0.000
M23.5 Chronic instability of knee
0.677 0.323 0.000
M23.1 Discoid meniscus (congenital)
0.677 0.323 0.000
M23.0 Cystic meniscus
0.677 0.323 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.676 0.324 0.000
M51 Other intervertebral disk disorders
0.675 0.325 0.000
H65-H75 Diseases of middle ear and mastoid
0.674 0.326 0.000
E87.7 Fluid overload
0.674 0.326 0.000
H60-H62 Diseases of external ear
0.673 0.327 0.000
K85 Acute pancreatitis
0.673 0.327 0.000
C44.5 Skin of trunk
0.673 0.327 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.673 0.327 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.673 0.327 0.000
J30.1 Allergic rhinitis due to pollen
0.672 0.328 0.000
S72.0 Fracture of neck of femur
0.672 0.328 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.672 0.328 0.000
M54.6 Pain in thoracic spine
0.671 0.329 0.000
M25.53 Pain in joint (Forearm)
0.670 0.330 0.000
M77 Other enthesopathies
0.670 0.330 0.000
M76 Enthesopathies of lower limb, excluding foot
0.670 0.330 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.670 0.330 0.000
M71 Other bursopathies
0.670 0.330 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.670 0.330 0.000
M25.54 Pain in joint (Hand)
0.669 0.331 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.669 0.331 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.667 0.333 0.000
N64.9 Disorder of breast, unspecified
0.667 0.333 0.000
H90 Conductive and sensorineural hearing loss
0.667 0.333 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.666 0.334 0.000
M23.30 Other meniscus derangements (Multiple sites)
0.666 0.334 0.000
M54.1 Radiculopathy
0.665 0.335 0.000
M25.46 Effusion of joint (Lower leg)
0.665 0.335 0.000
J37 Chronic laryngitis and laryngotracheitis
0.665 0.335 0.000
C43.8 Overlapping malignant melanoma of skin
0.664 0.336 0.000
C43.2 Malignant melanoma of ear and external auricular canal
0.664 0.336 0.000
C43.1 Malignant melanoma of eyelid, including canthus
0.664 0.336 0.000
C43.0 Malignant melanoma of lip
0.664 0.336 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.664 0.336 0.000
H25.8 Other senile cataract
0.664 0.336 0.000
K70-K77 Diseases of liver
0.663 0.337 0.000
M75.0 Adhesive capsulitis of shoulder
0.663 0.337 0.000
M75.5 Bursitis of shoulder
0.662 0.337 0.000
M79.67 Pain in limb (Ankle and foot)
0.662 0.338 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.662 0.338 0.000
S89 Other and unspecified injuries of lower leg
0.661 0.339 0.000
S88 Traumatic amputation of lower leg
0.661 0.339 0.000
S87 Crushing injury of lower leg
0.661 0.339 0.000
S86 Injury of muscle and tendon at lower leg level
0.661 0.339 0.000
S85 Injury of blood vessels at lower leg level
0.661 0.339 0.000
S84 Injury of nerves at lower leg level
0.661 0.339 0.000
S81 Open wound of lower leg
0.661 0.339 0.000
E50-E64 Other nutritional deficiencies
0.660 0.340 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.659 0.341 0.000
G45.4 Transient global amnesia
0.659 0.341 0.000
A41 Other septicaemia
0.659 0.341 0.000
M23.39 Other meniscus derangements (Unspecified ligament or Unspecified meniscus)
0.656 0.343 0.000
N13 Obstructive and reflux uropathy
0.655 0.345 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.655 0.345 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.655 0.345 0.000
R25 Abnormal involuntary movements
0.654 0.346 0.000
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness
0.653 0.347 0.000
M53 Other dorsopathies, not elsewhere classified
0.653 0.347 0.000
M79.8 Other specified soft tissue disorders
0.652 0.348 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.652 0.348 0.000
H55-H59 Other disorders of eye and adnexa
0.652 0.348 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.652 0.348 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.652 0.348 0.000
H10-H13 Disorders of conjunctiva
0.652 0.348 0.000
E87.0 Hyperosmolality and hypernatraemia
0.652 0.348 0.000
N36.8 Other specified disorders of urethra
0.651 0.348 0.000
G35 Multiple sclerosis
0.651 0.349 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.651 0.349 0.000
G41 Status epilepticus
0.651 0.349 0.000
M20.5 Other deformities of toe(s) (acquired)
0.651 0.349 0.000
H93 Other disorders of ear, not elsewhere classified
0.651 0.349 0.000
N60.2 Fibroadenosis of breast
0.650 0.349 0.000
M54.56 Low back pain (Lumbar region)
0.650 0.350 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.649 0.350 0.000
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)
0.649 0.351 0.000
N39.3 Stress incontinence
0.649 0.351 0.000
M31.6 Other giant cell arteritis
0.648 0.352 0.000
N60.9 Benign mammary dysplasia, unspecified
0.647 0.352 0.000
N60.4 Mammary duct ectasia
0.647 0.352 0.000
N60.0 Solitary cyst of breast
0.647 0.352 0.000
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee
0.647 0.353 0.000
M54.3 Sciatica
0.647 0.353 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.647 0.353 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.647 0.353 0.000
C79.6 Secondary malignant neoplasm of ovary
0.647 0.353 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.647 0.353 0.000
C79.2 Secondary malignant neoplasm of skin
0.647 0.353 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.647 0.353 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.647 0.353 0.000
N35.8 Other urethral stricture
0.646 0.354 0.000
N35.1 Postinfective urethral stricture, not elsewhere classified
0.646 0.354 0.000
N35.0 Posttraumatic urethral stricture
0.646 0.354 0.000
K82 Other diseases of gallbladder
0.646 0.354 0.000
N28 Other disorders of kidney and ureter, not elsewhere classified
0.645 0.355 0.000
T85.2 Mechanical complication of intraocular lens
0.645 0.355 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.645 0.355 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.644 0.356 0.000
J91 Pleural effusion in conditions classified elsewhere
0.643 0.356 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.643 0.357 0.000
N32.3 Diverticulum of bladder
0.643 0.357 0.000
G40 Epilepsy
0.643 0.357 0.000
J43.9 Emphysema, unspecified
0.642 0.358 0.000
J20-J22 Other acute lower respiratory infections
0.641 0.358 0.000
G45.9 Transient cerebral ischaemic attack, unspecified
0.641 0.359 0.000
H02 Other disorders of eyelid
0.641 0.359 0.000
M25.78 Osteophyte (Other)
0.640 0.359 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.640 0.360 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.640 0.360 0.000
G90 Disorders of autonomic nervous system
0.640 0.360 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.640 0.360 0.000
G92 Toxic encephalopathy
0.640 0.360 0.000
N61 Inflammatory disorders of breast
0.640 0.360 0.000
N60.3 Fibrosclerosis of breast
0.639 0.361 0.000
W20-W49 Exposure to inanimate mechanical forces
0.637 0.363 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.636 0.364 0.000
Y35-Y36 Legal intervention and operations of war
0.636 0.364 0.000
Y10-Y34 Event of undetermined intent
0.636 0.364 0.000
Y00-Y09 Assault
0.636 0.364 0.000
X85-X99 Assault
0.636 0.364 0.000
X60-X84 Intentional self-harm
0.636 0.364 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.636 0.364 0.000
X50-X57 Overexertion, travel and privation
0.636 0.364 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.636 0.364 0.000
X30-X39 Exposure to forces of nature
0.636 0.364 0.000
X20-X29 Contact with venomous animals and plants
0.636 0.364 0.000
X10-X19 Contact with heat and hot substances
0.636 0.364 0.000
X00-X09 Exposure to smoke, fire and flames
0.636 0.364 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.636 0.364 0.000
W75-W84 Other accidental threats to breathing
0.636 0.364 0.000
W65-W74 Accidental drowning and submersion
0.636 0.364 0.000
W50-W64 Exposure to animate mechanical forces
0.636 0.364 0.000
V98-V99 Other and unspecified transport accidents
0.636 0.364 0.000
V95-V97 Air and space transport accidents
0.636 0.364 0.000
V90-V94 Water transport accidents
0.636 0.364 0.000
V80-V89 Other land transport accidents
0.636 0.364 0.000
V70-V79 Bus occupant injured in transport accident
0.636 0.364 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.636 0.364 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.636 0.364 0.000
V40-V49 Car occupant injured in transport accident
0.636 0.364 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.636 0.364 0.000
V20-V29 Motorcycle rider injured in transport accident
0.636 0.364 0.000
V01-V09 Pedestrian injured in transport accident
0.636 0.364 0.000
E00-E07 Disorders of thyroid gland
0.636 0.364 0.000
J35 Chronic diseases of tonsils and adenoids
0.636 0.364 0.000
F40.2 Specific (isolated) phobias
0.634 0.365 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.634 0.366 0.000
J94 Other pleural conditions
0.634 0.366 0.000
B99-B99 Other infectious diseases
0.633 0.367 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.633 0.367 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.633 0.367 0.000
B65-B83 Helminthiases
0.633 0.367 0.000
B50-B64 Protozoal diseases
0.633 0.367 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.633 0.367 0.000
B15-B19 Viral hepatitis
0.633 0.367 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.633 0.367 0.000
A80-A89 Viral infections of the central nervous system
0.633 0.367 0.000
A75-A79 Rickettsioses
0.633 0.367 0.000
A70-A74 Other diseases caused by chlamydiae
0.633 0.367 0.000
A65-A69 Other spirochaetal diseases
0.633 0.367 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.633 0.367 0.000
A20-A28 Certain zoonotic bacterial diseases
0.633 0.367 0.000
A15-A19 Tuberculosis
0.633 0.367 0.000
N39.2 Orthostatic proteinuria, unspecified
0.633 0.367 0.000
N39.1 Persistent proteinuria, unspecified
0.633 0.367 0.000
C78.7 Secondary malignant neoplasm of liver
0.633 0.367 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.633 0.367 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.632 0.368 0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified
0.632 0.368 0.000
H94 Other disorders of ear in diseases classified elsewhere
0.632 0.368 0.000
H92 Otalgia and effusion of ear
0.632 0.368 0.000
R03.0 Elevated blood-pressure reading, without diagnosis of hypertension
0.632 0.368 0.000
S78 Traumatic amputation of hip and thigh
0.632 0.368 0.000
S77 Crushing injury of hip and thigh
0.632 0.368 0.000
S76 Injury of muscle and tendon at hip and thigh level
0.632 0.368 0.000
S75 Injury of blood vessels at hip and thigh level
0.632 0.368 0.000
S74 Injury of nerves at hip and thigh level
0.632 0.368 0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip
0.632 0.368 0.000
S71 Open wound of hip and thigh
0.632 0.368 0.000
S70 Superficial injury of hip and thigh
0.632 0.368 0.000
N36.2 Urethral caruncle
0.632 0.368 0.000
K35-K38 Diseases of appendix
0.631 0.369 0.000
G20 Parkinson's disease
0.631 0.369 0.000
G57 Mononeuropathies of lower limb
0.630 0.370 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.629 0.370 0.000
M80 Osteoporosis with pathological fracture
0.629 0.371 0.000
H53-H54 Visual disturbances and blindness
0.629 0.371 0.000
N19 Unspecified renal failure
0.629 0.371 0.000
V10-V19 Pedal cyclist injured in transport accident
0.629 0.371 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.628 0.372 0.000
J38.1 Polyp of vocal cord and larynx
0.628 0.372 0.000
M65 Synovitis and tenosynovitis
0.627 0.373 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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