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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs11225148
log Bayes Factor = 8.19694
Chromosome 11   position 102,009,280  (GRCh37) Explore rs11225148 on Ensembl!
Variant rs11225148 is listed in the   GWAS Catalog   ⇪
Variant rs11225148 is part of Cluster X0052

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
E70-E90 Metabolic disorders
0.999 0.001 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.996 0.004 0.000
M50-M54 Other dorsopathies
0.994 0.006 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.992 0.008 0.000
M54 Dorsalgia
0.985 0.015 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.982 0.018 0.000
Chapter XX External causes of morbidity and mortality
0.978 0.022 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.969 0.031 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.962 0.038 0.000
M54.1 Radiculopathy
0.961 0.039 0.000
E86 Volume depletion
0.961 0.039 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.960 0.040 0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.960 0.040 0.000
E00-E07 Disorders of thyroid gland
0.955 0.045 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.942 0.058 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.942 0.058 0.000
M50 Cervical disk disorders
0.940 0.060 0.000
M70-M79 Other soft tissue disorders
0.940 0.060 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.938 0.062 0.000
E20-E35 Disorders of other endocrine glands
0.937 0.063 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.933 0.067 0.000
M45-M49 Spondylopathies
0.929 0.071 0.000
E83 Disorders of mineral metabolism
0.927 0.073 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.926 0.074 0.000
M20-M25 Other joint disorders
0.925 0.075 0.000
O80-O84 Delivery
0.913 0.087 0.000
Chapter VII Diseases of the eye and adnexa
0.912 0.088 0.000
M54.16 Radiculopathy (Lumbar region)
0.909 0.091 0.000
M54.2 Cervicalgia
0.909 0.091 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.907 0.093 0.000
H30-H36 Disorders of choroid and retina
0.903 0.097 0.000
H35 Other retinal disorders
0.902 0.098 0.000
O42 Premature rupture of membranes
0.902 0.098 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.902 0.098 0.000
R41.0 Disorientation, unspecified
0.900 0.100 0.000
H35.3 Degeneration of macula and posterior pole
0.899 0.101 0.000
R22.4 Localised swelling, mass and lump, lower limb
0.899 0.101 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.898 0.102 0.000
O60-O75 Complications of labour and delivery
0.898 0.102 0.000
M47 Spondylosis
0.895 0.105 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.893 0.107 0.000
L20-L30 Dermatitis and eczema
0.890 0.110 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.890 0.110 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.887 0.113 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.885 0.115 0.000
E87.5 Hyperkalaemia
0.884 0.116 0.000
M47.8 Other spondylosis
0.882 0.118 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.879 0.121 0.000
O63 Long labour
0.876 0.124 0.000
M23 Internal derangement of knee
0.870 0.130 0.000
M54.12 Radiculopathy (Cervical region)
0.870 0.130 0.000
T92 Sequelae of injuries of upper limb
0.870 0.130 0.000
Chapter II Neoplasms
0.869 0.131 0.000
Chapter I Certain infectious and parasitic diseases
0.868 0.132 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.868 0.132 0.000
R22.0 Localised swelling, mass and lump, head
0.858 0.142 0.000
O46.9 Antepartum haemorrhage, unspecified
0.856 0.144 0.000
R41.3 Other amnesia
0.856 0.144 0.000
M47.82 Other spondylosis (Cervical region)
0.855 0.145 0.000
M54.22 Cervicalgia (Cervical region)
0.854 0.146 0.000
M54.9 Dorsalgia, unspecified
0.853 0.147 0.000
T66-T78 Other and unspecified effects of external causes
0.851 0.149 0.000
S90-S99 Injuries to the ankle and foot
0.850 0.150 0.000
E04 Other non-toxic goitre
0.848 0.152 0.000
C15-C26 Malignant neoplasms of digestive organs
0.848 0.152 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.847 0.153 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.846 0.154 0.000
L30 Other dermatitis
0.841 0.159 0.000
T43.2 Other and unspecified antidepressants
0.840 0.160 0.000
W20-W49 Exposure to inanimate mechanical forces
0.838 0.162 0.000
E87.6 Hypokalaemia
0.836 0.164 0.000
E83.4 Disorders of magnesium metabolism
0.836 0.164 0.000
O63.1 Prolonged second stage (of labour)
0.836 0.164 0.000
O81 Single delivery by forceps and vacuum extractor
0.835 0.165 0.000
L50-L54 Urticaria and erythema
0.834 0.166 0.000
M50.3 Other cervical disk degeneration
0.832 0.168 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.829 0.171 0.000
E50-E64 Other nutritional deficiencies
0.828 0.172 0.000
M23.8 Other internal derangements of knee
0.828 0.172 0.000
E40-E46 Malnutrition
0.827 0.173 0.000
O47 False labour
0.827 0.173 0.000
E83.1 Disorders of iron metabolism
0.827 0.173 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.826 0.174 0.000
E87.7 Fluid overload
0.825 0.175 0.000
S40-S49 Injuries to the shoulder and upper arm
0.824 0.176 0.000
M80-M85 Disorders of bone density and structure
0.821 0.179 0.000
E23 Hypofunction and other disorders of pituitary gland
0.821 0.179 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.821 0.179 0.000
S10-S19 Injuries to the neck
0.820 0.180 0.000
E28 Ovarian dysfunction
0.819 0.181 0.000
M47.86 Other spondylosis (Lumbar region)
0.819 0.181 0.000
C18 Malignant neoplasm of colon
0.819 0.181 0.000
M22 Disorders of patella
0.815 0.185 0.000
E74 Other disorders of carbohydrate metabolism
0.812 0.188 0.000
O42.0 Premature rupture of membranes, onset of labour within 24 hours
0.812 0.188 0.000
E06 Thyroiditis
0.811 0.189 0.000
C18.0 Caecum
0.811 0.189 0.000
R46 Symptoms and signs involving appearance and behaviour
0.806 0.194 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.804 0.196 0.000
R22.2 Localised swelling, mass and lump, trunk
0.804 0.196 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.804 0.196 0.000
Q60-Q64 Congenital malformations of the urinary system
0.802 0.198 0.000
L30.9 Dermatitis, unspecified
0.800 0.200 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.798 0.202 0.000
E04.2 Non-toxic multinodular goitre
0.798 0.202 0.000
O42.9 Premature rupture of membranes, unspecified
0.798 0.202 0.000
M21 Other acquired deformities of limbs
0.796 0.204 0.000
Q00-Q07 Congenital malformations of the nervous system
0.794 0.206 0.000
Chapter XXII Codes for special purposes
0.794 0.206 0.000
M79.0 Rheumatism, unspecified
0.793 0.207 0.000
T79-T79 Certain early complications of trauma
0.793 0.207 0.000
R21 Rash and other nonspecific skin eruption
0.792 0.208 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.791 0.209 0.000
M79.8 Other specified soft tissue disorders
0.790 0.210 0.000
O80 Single spontaneous delivery
0.789 0.211 0.000
M22.2 Patellofemoral disorders
0.787 0.213 0.000
L29 Pruritus
0.786 0.214 0.000
R47-R49 Symptoms and signs involving speech and voice
0.784 0.216 0.000
M50.2 Other cervical disk displacement
0.783 0.217 0.000
C16 Malignant neoplasm of stomach
0.783 0.217 0.000
R22.9 Localised swelling, mass and lump, unspecified
0.783 0.217 0.000
E88 Other metabolic disorders
0.783 0.217 0.000
H35.9 Retinal disorder, unspecified
0.783 0.217 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.781 0.219 0.000
B35-B49 Mycoses
0.781 0.219 0.000
M23.3 Other meniscus derangements
0.780 0.220 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.779 0.221 0.000
L28 Lichen simplex chronicus and prurigo
0.778 0.222 0.000
R45 Symptoms and signs involving emotional state
0.778 0.222 0.000
O46.8 Other antepartum haemorrhage
0.777 0.223 0.000
C60-C63 Malignant neoplasms of male genital organs
0.776 0.224 0.000
R80 Isolated proteinuria
0.775 0.225 0.000
R22.3 Localised swelling, mass and lump, upper limb
0.773 0.227 0.000
M47.80 Other spondylosis (Multiple sites in spine)
0.773 0.227 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.767 0.233 0.000
M54.3 Sciatica
0.764 0.236 0.000
Y44 Agents primarily affecting blood constituents
0.764 0.236 0.000
C25 Malignant neoplasm of pancreas
0.762 0.238 0.000
E89.2 Postprocedural hypoparathyroidism
0.761 0.239 0.000
M76 Enthesopathies of lower limb, excluding foot
0.760 0.240 0.000
V10-V19 Pedal cyclist injured in transport accident
0.760 0.240 0.000
M91-M94 Chondropathies
0.758 0.242 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.757 0.243 0.000
M50.9 Cervical disk disorder, unspecified
0.756 0.244 0.000
Q21 Congenital malformations of cardiac septa
0.756 0.244 0.000
E89.3 Postprocedural hypopituitarism
0.756 0.244 0.000
O63.9 Long labour, unspecified
0.753 0.247 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.750 0.250 0.000
Y40 Systemic antibiotics
0.748 0.252 0.000
M54.90 Dorsalgia, unspecified (Multiple sites in spine)
0.748 0.252 0.000
T98 Sequelae of other and unspecified effects of external causes
0.747 0.253 0.000
O81.4 Vacuum extractor delivery
0.746 0.254 0.000
T36 Poisoning by systemic antibiotics
0.746 0.254 0.000
T78 Adverse effects, not elsewhere classified
0.746 0.254 0.000
A30-A49 Other bacterial diseases
0.746 0.254 0.000
S91 Open wound of ankle and foot
0.745 0.255 0.000
H35.0 Background retinopathy and retinal vascular changes
0.744 0.256 0.000
O85-O92 Complications predominantly related to the puerperium
0.744 0.256 0.000
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.742 0.258 0.000
O80.0 Spontaneous vertex delivery
0.741 0.259 0.000
R43 Disturbances of smell and taste
0.741 0.259 0.000
C51-C58 Malignant neoplasms of female genital organs
0.740 0.260 0.000
H35.6 Retinal haemorrhage
0.737 0.263 0.000
M50.0 Cervical disk disorder with myelopathy
0.737 0.263 0.000
S60-S69 Injuries to the wrist and hand
0.737 0.263 0.000
Q50-Q56 Congenital malformations of genital organs
0.737 0.263 0.000
R06 Abnormalities of breathing
0.737 0.263 0.000
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.736 0.264 0.000
E83.3 Disorders of phosphorus metabolism
0.736 0.264 0.000
Y85 Sequelae of transport accidents
0.736 0.264 0.000
T18 Foreign body in alimentary tract
0.736 0.264 0.000
H43-H45 Disorders of vitreous body and globe
0.734 0.266 0.000
M54.96 Dorsalgia, unspecified (Lumbar region)
0.734 0.266 0.000
R82 Other abnormal findings in urine
0.733 0.267 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.733 0.267 0.000
M79.09 Rheumatism, unspecified (Site unspecified)
0.732 0.268 0.000
Y00-Y09 Assault
0.731 0.269 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.731 0.269 0.000
Q80-Q89 Other congenital malformations
0.730 0.270 0.000
L53 Other erythematous conditions
0.729 0.271 0.000
R44.3 Hallucinations, unspecified
0.728 0.272 0.000
E22 Hyperfunction of pituitary gland
0.727 0.273 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.727 0.273 0.000
C23 Malignant neoplasm of gallbladder
0.727 0.273 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.726 0.274 0.000
R06.0 Dyspnoea
0.726 0.274 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.725 0.275 0.000
W50-W64 Exposure to animate mechanical forces
0.725 0.275 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.725 0.275 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.724 0.276 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.724 0.276 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.724 0.276 0.000
X50-X57 Overexertion, travel and privation
0.724 0.276 0.000
O47.0 False labour before 37 completed weeks of gestation
0.723 0.277 0.000
O44 Placenta praevia
0.722 0.277 0.000
C61 Malignant neoplasm of prostate
0.722 0.278 0.000
W25 Contact with sharp glass
0.721 0.279 0.000
V40-V49 Car occupant injured in transport accident
0.721 0.279 0.000
T92.1 Sequelae of fracture of arm
0.720 0.280 0.000
X60-X84 Intentional self-harm
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
Y48 Anaesthetics and therapeutic gases
0.717 0.283 0.000
Y87 Sequelae of intentional self-harm, assault and events of undetermined intent
0.716 0.283 0.000
E85 Amyloidosis
0.716 0.284 0.000
E84 Cystic fibrosis
0.716 0.284 0.000
E79 Disorders of purine and pyrimidine metabolism
0.716 0.284 0.000
E77 Disorders of glycoprotein metabolism
0.716 0.284 0.000
E76 Disorders of glycosaminoglycan metabolism
0.716 0.284 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.716 0.284 0.000
E72 Other disorders of amino-acid metabolism
0.716 0.284 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.716 0.284 0.000
E70 Disorders of aromatic amino-acid metabolism
0.716 0.284 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.716 0.284 0.000
C18.3 Hepatic flexure
0.714 0.286 0.000
T33-T35 Frostbite
0.714 0.286 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.714 0.286 0.000
T00-T07 Injuries involving multiple body regions
0.714 0.286 0.000
M60-M63 Disorders of muscles
0.714 0.286 0.000
M53 Other dorsopathies, not elsewhere classified
0.713 0.287 0.000
O69.1 Labour and delivery complicated by cord around neck, with compression
0.713 0.287 0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.713 0.287 0.000
E28.2 Polycystic ovarian syndrome
0.710 0.290 0.000
H10-H13 Disorders of conjunctiva
0.710 0.290 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.710 0.290 0.000
M77 Other enthesopathies
0.710 0.290 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.710 0.290 0.000
X20-X29 Contact with venomous animals and plants
0.709 0.290 0.000
T91 Sequelae of injuries of neck and trunk
0.709 0.291 0.000
M23.84 Other internal derangements of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.709 0.291 0.000
H35.2 Other proliferative retinopathy
0.709 0.291 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.708 0.292 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.708 0.292 0.000
E06.3 Autoimmune thyroiditis
0.708 0.292 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.708 0.292 0.000
Q24 Other congenital malformations of heart
0.707 0.293 0.000
M54.8 Other dorsalgia
0.706 0.294 0.000
M54.0 Panniculitis affecting regions of neck and back
0.706 0.294 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.705 0.295 0.000
S90 Superficial injury of ankle and foot
0.705 0.295 0.000
T93 Sequelae of injuries of lower limb
0.704 0.296 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.704 0.296 0.000
E46 Unspecified protein-energy malnutrition
0.704 0.296 0.000
E24 Cushing's syndrome
0.704 0.296 0.000
E73 Lactose intolerance
0.702 0.297 0.000
T92.2 Sequelae of fracture at wrist and hand level
0.702 0.298 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.702 0.298 0.000
M24 Other specific joint derangements
0.702 0.298 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.701 0.299 0.000
Y35-Y36 Legal intervention and operations of war
0.701 0.299 0.000
Y10-Y34 Event of undetermined intent
0.701 0.299 0.000
X85-X99 Assault
0.701 0.299 0.000
X30-X39 Exposure to forces of nature
0.701 0.299 0.000
X10-X19 Contact with heat and hot substances
0.701 0.299 0.000
X00-X09 Exposure to smoke, fire and flames
0.701 0.299 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.701 0.299 0.000
W75-W84 Other accidental threats to breathing
0.701 0.299 0.000
W65-W74 Accidental drowning and submersion
0.701 0.299 0.000
V98-V99 Other and unspecified transport accidents
0.701 0.299 0.000
V95-V97 Air and space transport accidents
0.701 0.299 0.000
V90-V94 Water transport accidents
0.701 0.299 0.000
V70-V79 Bus occupant injured in transport accident
0.701 0.299 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.701 0.299 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.701 0.299 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.701 0.299 0.000
V01-V09 Pedestrian injured in transport accident
0.701 0.299 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.701 0.299 0.000
O42.1 Premature rupture of membranes, onset of labour after 24 hours
0.701 0.299 0.000
L52 Erythema nodosum
0.701 0.299 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.700 0.300 0.000
B37 Candidiasis
0.700 0.300 0.000
O73 Retained placenta and membranes, without haemorrhage
0.700 0.300 0.000
C16.9 Stomach, unspecified
0.700 0.300 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.699 0.301 0.000
O72 Postpartum haemorrhage
0.699 0.301 0.000
L28.0 Lichen simplex chronicus
0.698 0.302 0.000
M00-M03 Infectious arthropathies
0.698 0.302 0.000
R20 Disturbances of skin sensation
0.697 0.303 0.000
S70-S79 Injuries to the hip and thigh
0.697 0.303 0.000
E07 Other disorders of thyroid
0.696 0.304 0.000
M25 Other joint disorders, not elsewhere classified
0.696 0.304 0.000
M54.4 Lumbago with sciatica
0.694 0.306 0.000
M54.94 Dorsalgia, unspecified (Thoracic region)
0.692 0.308 0.000
T92.5 Sequelae of injury of muscle and tendon of upper limb
0.691 0.308 0.000
Q21.1 Atrial septal defect
0.690 0.310 0.000
M54.19 Radiculopathy (Site unspecified)
0.689 0.311 0.000
M54.18 Radiculopathy (Sacral and sacrococcygeal region)
0.689 0.311 0.000
M54.17 Radiculopathy (Lumbosacral region)
0.689 0.311 0.000
M54.15 Radiculopathy (Thoracolumbar region)
0.689 0.311 0.000
M54.14 Radiculopathy (Thoracic region)
0.689 0.311 0.000
M54.13 Radiculopathy (Cervicothoracic region)
0.689 0.311 0.000
M54.11 Radiculopathy (Occipito-atlanto-axial region)
0.689 0.311 0.000
M54.10 Radiculopathy (Multiple sites in spine)
0.689 0.311 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.689 0.311 0.000
Q35-Q37 Cleft lip and cleft palate
0.689 0.311 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.689 0.311 0.000
M23.5 Chronic instability of knee
0.689 0.311 0.000
R22.7 Localised swelling, mass and lump, multiple sites
0.688 0.311 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.687 0.312 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.687 0.313 0.000
E34 Other endocrine disorders
0.687 0.313 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.687 0.313 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.687 0.313 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.687 0.313 0.000
T16 Foreign body in ear
0.686 0.314 0.000
E20 Hypoparathyroidism
0.686 0.314 0.000
M80 Osteoporosis with pathological fracture
0.685 0.315 0.000
O81.0 Low forceps delivery
0.685 0.315 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.685 0.315 0.000
E00 Congenital iodine-deficiency syndrome
0.685 0.315 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.685 0.315 0.000
M86-M90 Other osteopathies
0.684 0.316 0.000
M40-M43 Deforming dorsopathies
0.683 0.317 0.000
H34 Retinal vascular occlusions
0.683 0.317 0.000
L29.9 Pruritus, unspecified
0.683 0.317 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.682 0.318 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.681 0.319 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.681 0.319 0.000
T92.3 Sequelae of dislocation, sprain and strain of upper limb
0.679 0.321 0.000
X59 Exposure to unspecified factor
0.679 0.321 0.000
E74.3 Other disorders of intestinal carbohydrate absorption
0.678 0.322 0.000
E26 Hyperaldosteronism
0.677 0.323 0.000
E78.0 Pure hypercholesterolaemia
0.677 0.323 0.000
O63.0 Prolonged first stage (of labour)
0.676 0.324 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.676 0.324 0.000
S19 Other and unspecified injuries of neck
0.676 0.324 0.000
O45 Premature separation of placenta [abruptio placentae]
0.675 0.324 0.000
O33 Maternal care for known or suspected disproportion
0.675 0.324 0.000
O31 Complications specific to multiple gestation
0.675 0.324 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.675 0.325 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.675 0.325 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.675 0.325 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.675 0.325 0.000
M45 Ankylosing spondylitis
0.675 0.325 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.675 0.325 0.000
M54.37 Sciatica (Lumbosacral region)
0.674 0.326 0.000
E55 Vitamin D deficiency
0.674 0.326 0.000
M50.8 Other cervical disk disorders
0.674 0.326 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.674 0.326 0.000
M23.0 Cystic meniscus
0.674 0.326 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.674 0.326 0.000
D46 Myelodysplastic syndromes
0.673 0.327 0.000
B37.8 Candidiasis of other sites
0.673 0.327 0.000
V80-V89 Other land transport accidents
0.673 0.327 0.000
T95 Sequelae of burns, corrosions and frostbite
0.673 0.327 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.673 0.327 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.673 0.327 0.000
R22.1 Localised swelling, mass and lump, neck
0.673 0.327 0.000
R02 Gangrene, not elsewhere classified
0.673 0.327 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.672 0.328 0.000
E32 Diseases of thymus
0.672 0.328 0.000
E31 Polyglandular dysfunction
0.672 0.328 0.000
E30 Disorders of puberty, not elsewhere classified
0.672 0.328 0.000
E25 Adrenogenital disorders
0.672 0.328 0.000
M21.6 Other acquired deformities of ankle and foot
0.671 0.329 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.670 0.329 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.670 0.329 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.670 0.330 0.000
M79.86 Other specified soft tissue disorders (Lower leg)
0.670 0.330 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.670 0.330 0.000
W44 Foreign body entering into or through eye or natural orifice
0.670 0.330 0.000
M79.89 Other specified soft tissue disorders (Site unspecified)
0.669 0.330 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.669 0.331 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.669 0.331 0.000
R41.1 Anterograde amnesia
0.669 0.331 0.000
M85 Other disorders of bone density and structure
0.668 0.331 0.000
W00-W19 Falls
0.668 0.332 0.000
D48.1 Connective and other soft tissue
0.668 0.332 0.000
R41.2 Retrograde amnesia
0.667 0.333 0.000
C25.2 Tail of pancreas
0.667 0.333 0.000
E53 Deficiency of other B group vitamins
0.667 0.333 0.000
E23.0 Hypopituitarism
0.667 0.333 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.666 0.334 0.000
T46.4 Angiotensin-converting-enzyme inhibitors
0.666 0.334 0.000
T92.9 Sequelae of unspecified injury of upper limb
0.666 0.334 0.000
M49 Spondylopathies in diseases classified elsewhere
0.666 0.334 0.000
E04.1 Non-toxic single thyroid nodule
0.665 0.335 0.000
E83.9 Disorder of mineral metabolism, unspecified
0.664 0.335 0.000
E83.8 Other disorders of mineral metabolism
0.664 0.335 0.000
E83.2 Disorders of zinc metabolism
0.664 0.335 0.000
E83.0 Disorders of copper metabolism
0.664 0.335 0.000
E87.4 Mixed disorder of acid-base balance
0.664 0.336 0.000
R87 Abnormal findings in specimens from female genital organs
0.664 0.336 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.663 0.337 0.000
M33 Dermatopolymyositis
0.663 0.337 0.000
M32 Systemic lupus erythematosus
0.663 0.337 0.000
M30 Polyarteritis nodosa and related conditions
0.663 0.337 0.000
M79.1 Myalgia
0.662 0.338 0.000
M71 Other bursopathies
0.661 0.339 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.660 0.340 0.000
M34 Systemic sclerosis
0.659 0.341 0.000
L27 Dermatitis due to substances taken internally
0.658 0.342 0.000
A49 Bacterial infection of unspecified site
0.656 0.344 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.656 0.344 0.000
R46.8 Other symptoms and signs involving appearance and behaviour
0.655 0.345 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.655 0.345 0.000
O84 Multiple delivery
0.654 0.346 0.000
O83 Other assisted single delivery
0.654 0.346 0.000
L53.9 Erythematous condition, unspecified
0.653 0.347 0.000
E23.7 Disorder of pituitary gland, unspecified
0.653 0.347 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.653 0.347 0.000
M23.83 Other internal derangements of knee (Medial collateral ligament or Other and unspecified medial meniscus)
0.653 0.347 0.000
R45.6 Physical violence
0.653 0.347 0.000
T14 Injury of unspecified body region
0.652 0.348 0.000
M54.29 Cervicalgia-Site unspe
0.651 0.348 0.000
M54.28 Cervicalgia-Sacral/sacrococ
0.651 0.348 0.000
M54.27 Cervicalgia-Lumbosacral
0.651 0.348 0.000
M54.26 Cervicalgia-Lumbar
0.651 0.348 0.000
M54.25 Cervicalgia-Thoracolumbar
0.651 0.348 0.000
M54.24 Cervicalgia-Thoracic
0.651 0.348 0.000
M54.23 Cervicalgia (Cervicothoracic region)
0.651 0.348 0.000
M54.21 Cervicalgia (Occipito-atlanto-axial region)
0.651 0.348 0.000
M54.20 Cervicalgia-Mult site
0.651 0.348 0.000
T90 Sequelae of injuries of head
0.651 0.349 0.000
E27 Other disorders of adrenal gland
0.650 0.350 0.000
O46.0 Antepartum haemorrhage with coagulation defect
0.650 0.350 0.000
M79.5 Residual foreign body in soft tissue
0.649 0.351 0.000
S91.3 Open wound of other parts of foot
0.649 0.351 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.649 0.351 0.000
R47 Speech disturbances, not elsewhere classified
0.649 0.351 0.000
O41 Other disorders of amniotic fluid and membranes
0.648 0.352 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.648 0.352 0.000
H30 Chorioretinal inflammation
0.648 0.352 0.000
O71 Other obstetric trauma
0.648 0.352 0.000
O16 Unspecified maternal hypertension
0.648 0.352 0.000
E23.2 Diabetes insipidus
0.647 0.353 0.000
H35.1 Retinopathy of prematurity
0.647 0.353 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.647 0.353 0.000
O42.2 Premature rupture of membranes, labour delayed by therapy
0.647 0.353 0.000
L10-L14 Bullous disorders
0.647 0.353 0.000
M79.6 Pain in limb
0.646 0.354 0.000
M79.7 Fibromyalgia
0.646 0.354 0.000
Q63 Other congenital malformations of kidney
0.645 0.355 0.000
Y59 Other and unspecified vaccines and biological substances
0.644 0.356 0.000
Y58 Bacterial vaccines
0.644 0.356 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.644 0.356 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.644 0.356 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.644 0.356 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.644 0.356 0.000
O74 Complications of anaesthesia during labour and delivery
0.644 0.356 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.644 0.356 0.000
O60 Preterm delivery
0.644 0.356 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.643 0.357 0.000
Y89 Sequelae of other external causes
0.643 0.357 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.643 0.357 0.000
O47.1 False labour at or after 37 completed weeks of gestation
0.642 0.358 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.641 0.358 0.000
M47.1 Other spondylosis with myelopathy
0.641 0.359 0.000
A80-A89 Viral infections of the central nervous system
0.641 0.359 0.000
T18.1 Foreign body in oesophagus
0.641 0.359 0.000
E87.0 Hyperosmolality and hypernatraemia
0.641 0.359 0.000
C17 Malignant neoplasm of small intestine
0.641 0.359 0.000
R85 Abnormal findings in specimens from digestive organs and abdominal cavity
0.641 0.359 0.000
C53 Malignant neoplasm of cervix uteri
0.641 0.359 0.000
L29.8 Other pruritus
0.640 0.360 0.000
M79.9 Soft tissue disorder, unspecified
0.640 0.360 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.640 0.360 0.000
M79.3 Panniculitis, unspecified
0.640 0.360 0.000
M79.2 Neuralgia and neuritis, unspecified
0.640 0.360 0.000
L50 Urticaria
0.639 0.361 0.000
L25 Unspecified contact dermatitis
0.638 0.362 0.000
L24 Irritant contact dermatitis
0.638 0.362 0.000
L23 Allergic contact dermatitis
0.638 0.362 0.000
L21 Seborrhoeic dermatitis
0.638 0.362 0.000
L20 Atopic dermatitis
0.638 0.362 0.000
L26 Exfoliative dermatitis
0.638 0.362 0.000
L22 Diaper [napkin] dermatitis
0.638 0.362 0.000
E28.3 Primary ovarian failure
0.638 0.362 0.000
M48 Other spondylopathies
0.638 0.362 0.000
W25.9 Unspecified place
0.638 0.362 0.000
V20-V29 Motorcycle rider injured in transport accident
0.638 0.362 0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.638 0.362 0.000
E89.8 Other postprocedural endocrine and metabolic disorders
0.638 0.362 0.000
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.638 0.362 0.000
E89.5 Postprocedural testicular hypofunction
0.638 0.362 0.000
E89.4 Postprocedural ovarian failure
0.638 0.362 0.000
E89.1 Postprocedural hypoinsulinaemia
0.638 0.362 0.000
W49 Exposure to other and unspecified inanimate mechanical forces
0.637 0.363 0.000
T17 Foreign body in respiratory tract
0.637 0.363 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.636 0.364 0.000
L30.8 Other specified dermatitis
0.636 0.364 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.636 0.364 0.000
R46.4 Slowness and poor responsiveness
0.636 0.364 0.000
Y57 Other and unspecified drugs and medicaments
0.636 0.364 0.000
T43.9 Psychotropic drug, unspecified
0.636 0.364 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.636 0.364 0.000
T43.6 Psychostimulants with abuse potential
0.636 0.364 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.636 0.364 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.636 0.364 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.635 0.365 0.000
R84 Abnormal findings in specimens from respiratory organs and thorax
0.635 0.365 0.000
S00-S09 Injuries to the head
0.635 0.365 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.634 0.365 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.634 0.365 0.000
Q07 Other congenital malformations of nervous system
0.634 0.366 0.000
R40 Somnolence, stupor and coma
0.634 0.366 0.000
C18.6 Descending colon
0.633 0.367 0.000
B25-B34 Other viral diseases
0.633 0.367 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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