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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs112424909
log Bayes Factor = 17.4922
Chromosome 18   position 9,705,858  (GRCh37) Explore rs112424909 on Ensembl!
Variant rs112424909 is part of Cluster X0026

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
C64-C68 Malignant neoplasms of urinary tract
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.998 0.002 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.998 0.002 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.998 0.002 0.000
I30-I52 Other forms of heart disease
0.998 0.002 0.000
Z92 Personal history of medical treatment
0.997 0.003 0.000
C67 Malignant neoplasm of bladder
0.996 0.004 0.000
Chapter I Certain infectious and parasitic diseases
0.993 0.007 0.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system
0.992 0.008 0.000
Z92.3 Personal history of irradiation
0.989 0.011 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.988 0.012 0.000
Chapter X Diseases of the respiratory system
0.986 0.014 0.000
C15-C26 Malignant neoplasms of digestive organs
0.983 0.017 0.000
Z93 Artificial opening status
0.980 0.020 0.000
J30-J39 Other diseases of upper respiratory tract
0.978 0.022 0.000
C67.9 Bladder, unspecified
0.976 0.024 0.000
Z92.6 Personal history of chemotherapy for neoplastic disease
0.976 0.024 0.000
I35 Nonrheumatic aortic valve disorders
0.968 0.032 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.967 0.033 0.000
Chapter VI Diseases of the nervous system
0.963 0.037 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.961 0.039 0.000
T81 Complications of procedures, not elsewhere classified
0.960 0.040 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.958 0.042 0.000
I35.0 Aortic (valve) stenosis
0.944 0.056 0.000
Z85 Personal history of malignant neoplasm
0.944 0.056 0.000
Z85.5 Personal history of malignant neoplasm of urinary tract
0.935 0.065 0.000
Z82.3 Family history of stroke
0.932 0.068 0.000
B95-B98 Bacterial, viral and other infectious agents
0.927 0.073 0.000
J09-J18 Influenza and pneumonia
0.925 0.075 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.925 0.075 0.000
Z93.3 Colostomy status
0.924 0.076 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.920 0.080 0.000
S60-S69 Injuries to the wrist and hand
0.918 0.082 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.912 0.088 0.000
I51 Complications and ill-defined descriptions of heart disease
0.911 0.089 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.909 0.091 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.909 0.091 0.000
J33 Nasal polyp
0.906 0.094 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.904 0.096 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.903 0.097 0.000
Z50 Care involving use of rehabilitation procedures
0.902 0.098 0.000
Z03 Medical observation and evaluation for suspected diseases and conditions
0.902 0.098 0.000
G40-G47 Episodic and paroxysmal disorders
0.900 0.100 0.000
J36 Peritonsillar abscess
0.899 0.101 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.898 0.102 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.896 0.104 0.000
C16 Malignant neoplasm of stomach
0.895 0.105 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.892 0.108 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.891 0.109 0.000
C15 Malignant neoplasm of oesophagus
0.891 0.109 0.000
J33.0 Polyp of nasal cavity
0.889 0.111 0.000
Chapter XXII Codes for special purposes
0.887 0.113 0.000
Z03.5 Observation for other suspected cardiovascular diseases
0.886 0.114 0.000
Chapter VII Diseases of the eye and adnexa
0.885 0.115 0.000
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified
0.880 0.120 0.000
I86 Varicose veins of other sites
0.878 0.122 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.876 0.124 0.000
I05-I09 Chronic rheumatic heart diseases
0.874 0.126 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.873 0.127 0.000
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified
0.869 0.131 0.000
H30-H36 Disorders of choroid and retina
0.869 0.131 0.000
I73 Other peripheral vascular diseases
0.868 0.132 0.000
I45 Other conduction disorders
0.865 0.135 0.000
I51.7 Cardiomegaly
0.865 0.135 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.865 0.135 0.000
I85 Oesophageal varices
0.864 0.136 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.863 0.137 0.000
Chapter XX External causes of morbidity and mortality
0.863 0.137 0.000
Z50.1 Other physical therapy
0.863 0.137 0.000
C60-C63 Malignant neoplasms of male genital organs
0.858 0.142 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.855 0.145 0.000
I44 Atrioventricular and left bundle-branch block
0.854 0.146 0.000
I42 Cardiomyopathy
0.853 0.147 0.000
I82 Other venous embolism and thrombosis
0.853 0.147 0.000
I73.9 Peripheral vascular disease, unspecified
0.853 0.147 0.000
G45.9 Transient cerebral ischaemic attack, unspecified
0.852 0.148 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.851 0.149 0.000
J18 Pneumonia, organism unspecified
0.850 0.150 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.846 0.154 0.000
I30 Acute pericarditis
0.846 0.154 0.000
C67.2 Lateral wall of bladder
0.846 0.154 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.845 0.155 0.000
H35 Other retinal disorders
0.843 0.157 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.843 0.157 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.840 0.160 0.000
Z08.0 Follow-up examination after surgery for malignant neoplasm
0.835 0.165 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.832 0.168 0.000
T81.4 Infection following a procedure, not elsewhere classified
0.831 0.169 0.000
B25-B34 Other viral diseases
0.830 0.170 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.830 0.170 0.000
J18.9 Pneumonia, unspecified
0.829 0.171 0.000
I60-I69 Cerebrovascular diseases
0.829 0.171 0.000
C66 Malignant neoplasm of ureter
0.828 0.172 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.825 0.175 0.000
C67.4 Posterior wall of bladder
0.825 0.175 0.000
T79-T79 Certain early complications of trauma
0.824 0.175 0.000
Z93.4 Other artificial openings of gastro-intestinal tract status
0.822 0.178 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.821 0.179 0.000
C25 Malignant neoplasm of pancreas
0.821 0.179 0.000
I84 Haemorrhoids
0.820 0.180 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.820 0.180 0.000
Z03.3 Observation for suspected nervous system disorder
0.819 0.181 0.000
Z92.1 Personal history of long-term (current) use of anticoagulants
0.819 0.181 0.000
I44.7 Left bundle-branch block, unspecified
0.817 0.183 0.000
Z94 Transplanted organ and tissue status
0.817 0.183 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.817 0.183 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.816 0.184 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.813 0.187 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.812 0.188 0.000
E70-E90 Metabolic disorders
0.812 0.188 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.810 0.190 0.000
A30-A49 Other bacterial diseases
0.808 0.192 0.000
T82.1 Mechanical complication of cardiac electronic device
0.807 0.193 0.000
C67.3 Anterior wall of bladder
0.807 0.193 0.000
C67.0 Trigone of bladder
0.804 0.196 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.803 0.197 0.000
Z08.7 Follow-up examination after combined treatment for malignant neoplasm
0.801 0.199 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.801 0.199 0.000
C15.9 Oesophagus, unspecified
0.800 0.200 0.000
J38.0 Paralysis of vocal cords and larynx
0.794 0.206 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.793 0.207 0.000
J60-J70 Lung diseases due to external agents
0.793 0.207 0.000
I81 Portal vein thrombosis
0.792 0.208 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.791 0.209 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.790 0.210 0.000
Z89 Acquired absence of limb
0.790 0.210 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.788 0.212 0.000
A80-A89 Viral infections of the central nervous system
0.787 0.213 0.000
E83 Disorders of mineral metabolism
0.786 0.214 0.000
E20-E35 Disorders of other endocrine glands
0.786 0.214 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.785 0.215 0.000
S61 Open wound of wrist and hand
0.782 0.218 0.000
I08 Multiple valve diseases
0.781 0.219 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.781 0.219 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.780 0.220 0.000
H33 Retinal detachments and breaks
0.777 0.223 0.000
I86.4 Gastric varices
0.777 0.223 0.000
Z50.5 Speech therapy
0.777 0.223 0.000
H35.3 Degeneration of macula and posterior pole
0.775 0.225 0.000
S80-S89 Injuries to the knee and lower leg
0.774 0.226 0.000
Z86 Personal history of certain other diseases
0.774 0.226 0.000
Z48 Other surgical follow-up care
0.771 0.229 0.000
Z93.5 Cystostomy status
0.771 0.229 0.000
T82.4 Mechanical complication of vascular dialysis catheter
0.770 0.230 0.000
C16.9 Stomach, unspecified
0.770 0.230 0.000
T87 Complications peculiar to reattachment and amputation
0.770 0.230 0.000
T86 Failure and rejection of transplanted organs and tissues
0.768 0.232 0.000
Z08.2 Follow-up examination after chemotherapy for malignant neoplasm
0.767 0.233 0.000
C16.0 Cardia
0.767 0.233 0.000
Z83 Family history of other specific disorders
0.767 0.233 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.767 0.233 0.000
Z86.4 Personal history of psychoactive substance abuse
0.766 0.234 0.000
Z93.1 Gastrostomy status
0.766 0.234 0.000
Q60-Q64 Congenital malformations of the urinary system
0.766 0.234 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.765 0.235 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.764 0.236 0.000
S90-S99 Injuries to the ankle and foot
0.763 0.236 0.000
Z82.7 Family history of congenital malformations, deformations and chromosomal abnormalities
0.763 0.237 0.000
I36 Nonrheumatic tricuspid valve disorders
0.762 0.237 0.000
I47 Paroxysmal tachycardia
0.762 0.238 0.000
D37.4 Colon
0.762 0.238 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.760 0.240 0.000
T92 Sequelae of injuries of upper limb
0.759 0.241 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.759 0.241 0.000
J35 Chronic diseases of tonsils and adenoids
0.758 0.242 0.000
I84.8 Unspecified haemorrhoids with other complications
0.758 0.242 0.000
Z90.8 Acquired absence of other organs
0.757 0.243 0.000
I85.0 Oesophageal varices with bleeding
0.757 0.243 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.757 0.243 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.756 0.244 0.000
J38.3 Other diseases of vocal cords
0.756 0.244 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.755 0.245 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.755 0.245 0.000
Z45 Adjustment and management of implanted device
0.751 0.249 0.000
G90-G99 Other disorders of the nervous system
0.751 0.249 0.000
Z87 Personal history of other diseases and conditions
0.751 0.249 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.751 0.249 0.000
S10-S19 Injuries to the neck
0.750 0.250 0.000
D37.5 Rectum
0.749 0.251 0.000
I49 Other cardiac arrhythmias
0.749 0.251 0.000
H33.3 Retinal breaks without detachment
0.749 0.251 0.000
T83.0 Mechanical complication of urinary (indwelling) catheter
0.748 0.252 0.000
Z80 Family history of malignant neoplasm
0.746 0.254 0.000
I78 Diseases of capillaries
0.746 0.254 0.000
C18 Malignant neoplasm of colon
0.744 0.256 0.000
T81.8 Other complications of procedures, not elsewhere classified
0.744 0.256 0.000
I80 Phlebitis and thrombophlebitis
0.744 0.256 0.000
R41.3 Other amnesia
0.743 0.257 0.000
C61 Malignant neoplasm of prostate
0.743 0.257 0.000
H35.8 Other specified retinal disorders
0.741 0.259 0.000
G70-G73 Diseases of myoneural junction and muscle
0.741 0.259 0.000
T93 Sequelae of injuries of lower limb
0.740 0.260 0.000
Z50.8 Care involving use of rehabilitation procedures
0.740 0.260 0.000
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level
0.739 0.261 0.000
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters
0.739 0.261 0.000
H10-H13 Disorders of conjunctiva
0.738 0.262 0.000
S64 Injury of nerves at wrist and hand level
0.738 0.262 0.000
C67.5 Bladder neck
0.737 0.263 0.000
T81.9 Unspecified complication of procedure
0.737 0.263 0.000
I30.9 Acute pericarditis, unspecified
0.737 0.263 0.000
Z46 Fitting and adjustment of other devices
0.735 0.265 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.735 0.265 0.000
J38.7 Other diseases of larynx
0.735 0.265 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.734 0.266 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.734 0.266 0.000
E83.4 Disorders of magnesium metabolism
0.733 0.267 0.000
C04 Malignant neoplasm of floor of mouth
0.733 0.267 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.733 0.267 0.000
B15-B19 Viral hepatitis
0.732 0.268 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.732 0.268 0.000
E50-E64 Other nutritional deficiencies
0.731 0.269 0.000
L40-L45 Papulosquamous disorders
0.731 0.269 0.000
A00-A09 Intestinal infectious diseases
0.730 0.270 0.000
Z93.2 Ileostomy status
0.730 0.270 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.730 0.270 0.000
Z87.1 Personal history of diseases of the digestive system
0.728 0.272 0.000
Z93.6 Other artificial openings of urinary tract status
0.727 0.273 0.000
B35-B49 Mycoses
0.727 0.273 0.000
I69 Sequelae of cerebrovascular disease
0.727 0.273 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.726 0.274 0.000
J38.5 Laryngeal spasm
0.724 0.276 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.723 0.277 0.000
Z97 Presence of other devices
0.722 0.278 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.722 0.278 0.000
J39 Other diseases of upper respiratory tract
0.720 0.280 0.000
C09 Malignant neoplasm of tonsil
0.719 0.281 0.000
Z93.0 Tracheostomy status
0.718 0.282 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.718 0.282 0.000
Z84 Family history of other conditions
0.717 0.283 0.000
Z81 Family history of mental and behavioural disorders
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system
0.717 0.283 0.000
C68 Malignant neoplasm of other and unspecified urinary organs
0.717 0.283 0.000
C65 Malignant neoplasm of renal pelvis
0.717 0.283 0.000
T33-T35 Frostbite
0.716 0.284 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.716 0.284 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.716 0.284 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.716 0.284 0.000
T00-T07 Injuries involving multiple body regions
0.716 0.284 0.000
C67.6 Ureteric orifice
0.716 0.284 0.000
Z82.8 Family history of other disabilities and chronic diseases leading to disablement, not elsewhere classified
0.716 0.284 0.000
Z82.6 Family history of arthritis and other diseases of the musculoskeletal system and connective tissue
0.716 0.284 0.000
Z82.5 Family history of asthma and other chronic lower respiratory diseases
0.716 0.284 0.000
Z82.2 Family history of deafness and hearing loss
0.716 0.284 0.000
Z82.1 Family history of blindness and visual loss
0.716 0.284 0.000
Z85.9 Personal history of malignant neoplasm, unspecified
0.715 0.284 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.715 0.284 0.000
I52 Other heart disorders in diseases classified elsewhere
0.715 0.285 0.000
I48 Atrial fibrillation and flutter
0.715 0.285 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.715 0.285 0.000
I41 Myocarditis in diseases classified elsewhere
0.715 0.285 0.000
I40 Acute myocarditis
0.715 0.285 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.715 0.285 0.000
I37 Pulmonary valve disorders
0.715 0.285 0.000
I32 Pericarditis in diseases classified elsewhere
0.715 0.285 0.000
C21 Malignant neoplasm of anus and anal canal
0.715 0.285 0.000
Z92.9 Personal history of medical treatment, unspecified
0.715 0.285 0.000
Z92.5 Personal history of rehabilitation measures
0.715 0.285 0.000
C67.8 Overlapping lesion of bladder
0.714 0.286 0.000
C67.7 Urachus
0.714 0.286 0.000
C67.1 Dome of bladder
0.714 0.286 0.000
I45.3 Trifascicular block
0.714 0.286 0.000
I82.8 Embolism and thrombosis of other specified veins
0.714 0.286 0.000
S67 Crushing injury of wrist and hand
0.713 0.287 0.000
T83.3 Mechanical complication of intra-uterine contraceptive device
0.713 0.287 0.000
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters
0.713 0.287 0.000
B99-B99 Other infectious diseases
0.712 0.288 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.712 0.288 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.712 0.288 0.000
B65-B83 Helminthiases
0.712 0.288 0.000
B50-B64 Protozoal diseases
0.712 0.288 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.712 0.288 0.000
A75-A79 Rickettsioses
0.712 0.288 0.000
A70-A74 Other diseases caused by chlamydiae
0.712 0.288 0.000
A65-A69 Other spirochaetal diseases
0.712 0.288 0.000
A20-A28 Certain zoonotic bacterial diseases
0.712 0.288 0.000
A15-A19 Tuberculosis
0.712 0.288 0.000
J38.4 Oedema of larynx
0.710 0.290 0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis
0.710 0.290 0.000
Y40 Systemic antibiotics
0.709 0.291 0.000
Z49 Care involving dialysis
0.709 0.291 0.000
I88 Nonspecific lymphadenitis
0.709 0.291 0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts
0.708 0.292 0.000
C15.5 Lower third of oesophagus
0.708 0.292 0.000
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness
0.707 0.293 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.706 0.294 0.000
I45.8 Other specified conduction disorders
0.705 0.295 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.705 0.295 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.705 0.295 0.000
C17 Malignant neoplasm of small intestine
0.705 0.295 0.000
C23 Malignant neoplasm of gallbladder
0.705 0.295 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.704 0.296 0.000
T82.3 Mechanical complication of other vascular grafts
0.703 0.297 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.703 0.297 0.000
Z93.9 Artificial opening status, unspecified
0.702 0.297 0.000
Z93.8 Other artificial opening status
0.702 0.297 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.702 0.298 0.000
J37 Chronic laryngitis and laryngotracheitis
0.701 0.299 0.000
J31.0 Chronic rhinitis
0.701 0.299 0.000
I42.9 Cardiomyopathy, unspecified
0.700 0.299 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.700 0.300 0.000
I83 Varicose veins of lower extremities
0.700 0.300 0.000
D37.0 Lip, oral cavity and pharynx
0.699 0.301 0.000
D37.7 Other digestive organs
0.699 0.301 0.000
J14 Pneumonia due to Haemophilus influenzae
0.698 0.302 0.000
B01 Varicella [chickenpox]
0.698 0.302 0.000
Z99.2 Dependence on renal dialysis
0.698 0.302 0.000
Z03.4 Observation for suspected myocardial infarction
0.696 0.304 0.000
C22.9 Liver, unspecified
0.695 0.305 0.000
D00-D09 In situ neoplasms
0.695 0.305 0.000
R47-R49 Symptoms and signs involving speech and voice
0.695 0.305 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.695 0.305 0.000
J10 Influenza due to identified influenza virus
0.695 0.305 0.000
I35.8 Other aortic valve disorders
0.694 0.306 0.000
C25.0 Head of pancreas
0.694 0.306 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.694 0.306 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.694 0.306 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.694 0.306 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.694 0.306 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.694 0.306 0.000
I50 Heart failure
0.694 0.306 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.692 0.308 0.000
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract
0.690 0.310 0.000
I45.6 Preexcitation syndrome
0.690 0.310 0.000
Z85.2 Personal history of malignant neoplasm of other respiratory and intrathoracic organs
0.690 0.310 0.000
Z90.6 Acquired absence of other parts of urinary tract
0.689 0.311 0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters
0.688 0.312 0.000
T81.7 Vascular complications following a procedure, not elsewhere classified
0.688 0.312 0.000
T81.6 Acute reaction to foreign substance accidentally left during a procedure
0.688 0.312 0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure
0.688 0.312 0.000
T81.1 Shock during or resulting from a procedure, not elsewhere classified
0.688 0.312 0.000
Z99.3 Dependence on wheelchair
0.688 0.312 0.000
D47.2 Monoclonal gammopathy
0.688 0.312 0.000
Z50.4 Psychotherapy, not elsewhere classified
0.688 0.312 0.000
R30-R39 Symptoms and signs involving the urinary system
0.687 0.313 0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft
0.687 0.313 0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis
0.687 0.313 0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.687 0.313 0.000
E83.5 Disorders of calcium metabolism
0.687 0.313 0.000
I84.4 External haemorrhoids with other complications
0.685 0.315 0.000
I42.8 Other cardiomyopathies
0.685 0.315 0.000
I82.9 Embolism and thrombosis of unspecified vein
0.685 0.315 0.000
I27 Other pulmonary heart diseases
0.685 0.315 0.000
D47.4 Osteomyelofibrosis
0.685 0.315 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.683 0.316 0.000
T88.7 Unspecified adverse effect of drug or medicament
0.683 0.317 0.000
I86.1 Scrotal varices
0.683 0.317 0.000
B24 Unspecified human immunodeficiency virus [HIV] disease
0.683 0.317 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.682 0.318 0.000
C22.0 Liver cell carcinoma
0.682 0.318 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.682 0.318 0.000
G45.8 Other transient cerebral ischaemic attacks and related syndromes
0.682 0.318 0.000
T88.5 Other complications of anaesthesia
0.681 0.319 0.000
I31 Other diseases of pericardium
0.681 0.319 0.000
Z03.1 Observation for suspected malignant neoplasm
0.679 0.321 0.000
H35.5 Hereditary retinal dystrophy
0.679 0.321 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.679 0.321 0.000
Z54 Convalescence
0.679 0.321 0.000
I72 Other aneurysm
0.679 0.321 0.000
Z46.8 Fitting and adjustment of other specified devices
0.679 0.321 0.000
I10-I15 Hypertensive diseases
0.678 0.322 0.000
Z45.2 Adjustment and management of vascular access device
0.678 0.322 0.000
J90-J94 Other diseases of pleura
0.677 0.323 0.000
Z85.0 Personal history of malignant neoplasm of digestive organs
0.677 0.323 0.000
S61.0 Open wound of finger(s) without damage to nail
0.676 0.324 0.000
H34 Retinal vascular occlusions
0.676 0.324 0.000
L20-L30 Dermatitis and eczema
0.676 0.324 0.000
Z92.0 Personal history of contraception
0.675 0.324 0.000
Z90.1 Acquired absence of breast(s)
0.675 0.325 0.000
J38.1 Polyp of vocal cord and larynx
0.674 0.326 0.000
I87 Other disorders of veins
0.674 0.326 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.673 0.327 0.000
Q61 Cystic kidney disease
0.672 0.328 0.000
Z82.0 Family history of epilepsy and other diseases of the nervous system
0.671 0.329 0.000
Z85.7 Personal history of other malignant neoplasms of lymphoid, haematopoietic and related tissues
0.671 0.329 0.000
G30-G32 Other degenerative diseases of the nervous system
0.670 0.330 0.000
I44.3 Other and unspecified atrioventricular block
0.670 0.330 0.000
Z83.5 Family history of eye and ear disorders
0.669 0.331 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.669 0.331 0.000
D41.4 Bladder
0.668 0.331 0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters
0.668 0.332 0.000
E27 Other disorders of adrenal gland
0.668 0.332 0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.668 0.332 0.000
I51.9 Heart disease, unspecified
0.667 0.333 0.000
B25 Cytomegaloviral disease
0.667 0.333 0.000
H55-H59 Other disorders of eye and adnexa
0.667 0.333 0.000
Chapter VIII Diseases of the ear and mastoid process
0.666 0.334 0.000
B07 Viral warts
0.666 0.334 0.000
V40-V49 Car occupant injured in transport accident
0.664 0.336 0.000
J17 Pneumonia in diseases classified elsewhere
0.663 0.336 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.663 0.336 0.000
J12 Viral pneumonia, not elsewhere classified
0.663 0.336 0.000
J09 Influenza due to certain identified influenza virus
0.663 0.336 0.000
J38.6 Stenosis of larynx
0.663 0.336 0.000
J38.2 Nodules of vocal cords
0.663 0.336 0.000
Z94.4 Liver transplant status
0.663 0.337 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.663 0.337 0.000
Z85.6 Personal history of leukaemia
0.663 0.337 0.000
L40 Psoriasis
0.662 0.338 0.000
T91 Sequelae of injuries of neck and trunk
0.662 0.338 0.000
S69 Other and unspecified injuries of wrist and hand
0.661 0.338 0.000
G43 Migraine
0.661 0.338 0.000
H35.7 Separation of retinal layers
0.661 0.339 0.000
I85.9 Oesophageal varices without bleeding
0.661 0.339 0.000
B34 Viral infection of unspecified site
0.661 0.339 0.000
I47.1 Supraventricular tachycardia
0.661 0.339 0.000
G45.3 Amaurosis fugax
0.661 0.339 0.000
T88.4 Failed or difficult intubation
0.661 0.339 0.000
Z10 Routine general health check-up of defined subpopulation
0.659 0.340 0.000
T88.6 Anaphylactic shock due to adverse effect of correct drug or medicament properly administered
0.659 0.341 0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.659 0.341 0.000
S65 Injury of blood vessels at wrist and hand level
0.658 0.342 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.658 0.342 0.000
Z90.0 Acquired absence of part of head and neck
0.657 0.343 0.000
Q50-Q56 Congenital malformations of genital organs
0.656 0.344 0.000
Q80-Q89 Other congenital malformations
0.655 0.345 0.000
V20-V29 Motorcycle rider injured in transport accident
0.655 0.345 0.000
Z44 Fitting and adjustment of external prosthetic device
0.654 0.346 0.000
R39 Other symptoms and signs involving the urinary system
0.654 0.346 0.000
I51.6 Cardiovascular disease, unspecified
0.653 0.347 0.000
I51.5 Myocardial degeneration
0.653 0.347 0.000
I51.4 Myocarditis, unspecified
0.653 0.347 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.653 0.347 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.653 0.347 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.653 0.347 0.000
I51.0 Cardiac septal defect, acquired
0.653 0.347 0.000
Z29 Need for other prophylactic measures
0.652 0.348 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.652 0.348 0.000
Z92.8 Personal history of other medical treatment
0.652 0.348 0.000
C02.9 Tongue, unspecified
0.652 0.348 0.000
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft
0.651 0.349 0.000
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract
0.651 0.349 0.000
T83.2 Mechanical complication of graft of urinary organ
0.651 0.349 0.000
G20-G26 Extrapyramidal and movement disorders
0.651 0.349 0.000
J33.1 Polypoid sinus degeneration
0.650 0.350 0.000
G35 Multiple sclerosis
0.649 0.351 0.000
I84.6 Residual haemorrhoidal skin tags
0.649 0.351 0.000
J69 Pneumonitis due to solids and liquids
0.649 0.351 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.648 0.351 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.648 0.351 0.000
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx
0.647 0.353 0.000
C13 Malignant neoplasm of hypopharynx
0.647 0.353 0.000
C11 Malignant neoplasm of nasopharynx
0.647 0.353 0.000
C10 Malignant neoplasm of oropharynx
0.647 0.353 0.000
C08 Malignant neoplasm of other and unspecified major salivary glands
0.647 0.353 0.000
C06 Malignant neoplasm of other and unspecified parts of mouth
0.647 0.353 0.000
C05 Malignant neoplasm of palate
0.647 0.353 0.000
C03 Malignant neoplasm of gum
0.647 0.353 0.000
C00 Malignant neoplasm of lip
0.647 0.353 0.000
C12 Malignant neoplasm of pyriform sinus
0.647 0.353 0.000
C07 Malignant neoplasm of parotid gland
0.647 0.353 0.000
C01 Malignant neoplasm of base of tongue
0.647 0.353 0.000
U88 Agent resistant to multiple antibiotics
0.647 0.353 0.000
Z50.6 Orthoptic training
0.647 0.353 0.000
Z50.3 Drug rehabilitation
0.647 0.353 0.000
Z03.6 Observation for suspected toxic effect from ingested substance
0.646 0.353 0.000
Z03.2 Observation for suspected mental and behavioural disorders
0.646 0.353 0.000
Z03.0 Observation for suspected tuberculosis
0.646 0.353 0.000
I84.7 Unspecified thrombosed haemorrhoids
0.646 0.354 0.000
Z08.8 Follow-up examination after other treatment for malignant neoplasm
0.646 0.354 0.000
E86 Volume depletion
0.646 0.354 0.000
I33 Acute and subacute endocarditis
0.645 0.354 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.645 0.354 0.000
G41 Status epilepticus
0.645 0.354 0.000
D46 Myelodysplastic syndromes
0.645 0.355 0.000
W20-W49 Exposure to inanimate mechanical forces
0.645 0.355 0.000
C62 Malignant neoplasm of testis
0.645 0.355 0.000
D48.6 Breast
0.645 0.355 0.000
D37.9 Digestive organ, unspecified
0.644 0.356 0.000
D37.6 Liver, gallbladder and bile ducts
0.644 0.356 0.000
D37.3 Appendix
0.644 0.356 0.000
D37.2 Small intestine
0.644 0.356 0.000
D37.1 Stomach
0.644 0.356 0.000
Z85.3 Personal history of malignant neoplasm of breast
0.644 0.356 0.000
L50-L54 Urticaria and erythema
0.643 0.357 0.000
J11 Influenza, virus not identified
0.643 0.357 0.000
Z08.1 Follow-up examination after radiotherapy for malignant neoplasm
0.643 0.357 0.000
A41 Other septicaemia
0.642 0.358 0.000
C16.8 Overlapping lesion of stomach
0.642 0.358 0.000
C16.6 Greater curvature of stomach, unspecified
0.642 0.358 0.000
C16.5 Lesser curvature of stomach, unspecified
0.642 0.358 0.000
C16.4 Pylorus
0.642 0.358 0.000
C16.3 Pyloric antrum
0.642 0.358 0.000
C16.2 Body of stomach
0.642 0.358 0.000
C16.1 Fundus of stomach
0.642 0.358 0.000
S60 Superficial injury of wrist and hand
0.641 0.359 0.000
E65-E68 Obesity and other hyperalimentation
0.641 0.359 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.641 0.359 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.640 0.360 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.640 0.360 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.640 0.360 0.000
Q35-Q37 Cleft lip and cleft palate
0.640 0.360 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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