TreeWAS – Variant ID: rs114059502

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability
Chapter II Neoplasms	1.000	0.000
# Top node	1.000	0.000
Chapter XII Diseases of the skin and subcutaneous tissue	1.000	0.000
L80-L99 Other disorders of the skin and subcutaneous tissue	1.000	0.000
C43-C44 Melanoma and other malignant neoplasms of skin	0.999	0.001
L82 Seborrhoeic keratosis	0.999	0.001
C44 Other malignant neoplasms of skin	0.998	0.002
Chapter IX Diseases of the circulatory system	0.997	0.003
Chapter XIV Diseases of the genitourinary system	0.997	0.003
Chapter XI Diseases of the digestive system	0.995	0.005
D10-D36 Benign neoplasms	0.993	0.007
C44.3 Skin of other and unspecified parts of face	0.986	0.014
N17-N19 Renal failure	0.984	0.016
L40-L45 Papulosquamous disorders	0.978	0.022
I70-I79 Diseases of arteries, arterioles and capillaries	0.973	0.027
K70-K77 Diseases of liver	0.962	0.038
N20-N23 Urolithiasis	0.959	0.041
L40 Psoriasis	0.956	0.044
Chapter XX External causes of morbidity and mortality	0.954	0.046
I30-I52 Other forms of heart disease	0.952	0.048
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.944	0.056
N18 Chronic renal failure	0.940	0.060
I71 Aortic aneurysm and dissection	0.940	0.060
D22 Melanocytic naevi	0.936	0.064
N20 Calculus of kidney and ureter	0.933	0.067
L97 Ulcer of lower limb, not elsewhere classified	0.932	0.068
K50-K52 Noninfective enteritis and colitis	0.930	0.070
Chapter IV Endocrine, nutritional and metabolic diseases	0.929	0.071
D37-D48 Neoplasms of uncertain or unknown behaviour	0.922	0.078
K00-K14 Diseases of oral cavity, salivary glands and jaws	0.922	0.078
D00-D09 In situ neoplasms	0.922	0.078
I34 Nonrheumatic mitral valve disorders	0.921	0.079
L40.9 Psoriasis, unspecified	0.918	0.082
D23 Other benign neoplasms of skin	0.913	0.087
Chapter VI Diseases of the nervous system	0.913	0.087
C44.1 Skin of eyelid, including canthus	0.913	0.087
I34.0 Mitral (valve) insufficiency	0.903	0.097
L81 Other disorders of pigmentation	0.902	0.098
N20.0 Calculus of kidney	0.902	0.098
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.900	0.100
I47 Paroxysmal tachycardia	0.891	0.109
N19 Unspecified renal failure	0.891	0.109
L50-L54 Urticaria and erythema	0.877	0.123
N80-N98 Noninflammatory disorders of female genital tract	0.875	0.125
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.874	0.126
D24 Benign neoplasm of breast	0.871	0.129
Chapter VII Diseases of the eye and adnexa	0.871	0.129
E20-E35 Disorders of other endocrine glands	0.869	0.131
D17 Benign lipomatous neoplasm	0.869	0.131
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.868	0.132
D22.5 Melanocytic naevi of trunk	0.868	0.132
D10 Benign neoplasm of mouth and pharynx	0.867	0.133
I10-I15 Hypertensive diseases	0.861	0.139
N00-N08 Glomerular diseases	0.860	0.140
D18 Haemangioma and lymphangioma, any site	0.859	0.141
K20-K31 Diseases of oesophagus, stomach and duodenum	0.851	0.149
C44.0 Skin of lip	0.850	0.150
K90-K93 Other diseases of the digestive system	0.850	0.150
N25-N29 Other disorders of kidney and ureter	0.849	0.151
I95-I99 Other and unspecified disorders of the circulatory system	0.847	0.153
I20-I25 Ischaemic heart diseases	0.847	0.153
C44.6 Skin of upper limb, including shoulder	0.846	0.154
K20 Oesophagitis	0.845	0.155
L40.0 Psoriasis vulgaris	0.841	0.159
K50 Crohn's disease [regional enteritis]	0.840	0.160
M15-M19 Arthrosis	0.839	0.161
M19 Other arthrosis	0.838	0.162
L81.4 Other melanin hyperpigmentation	0.838	0.162
K74 Fibrosis and cirrhosis of liver	0.837	0.163
S70-S79 Injuries to the hip and thigh	0.837	0.163
M19.9 Arthrosis, unspecified	0.833	0.167
K76 Other diseases of liver	0.832	0.168
D06 Carcinoma in situ of cervix uteri	0.831	0.169
C44.4 Skin of scalp and neck	0.830	0.170
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified	0.826	0.174
N18.9 Chronic renal failure, unspecified	0.821	0.179
N17 Acute renal failure	0.820	0.180
C64-C68 Malignant neoplasms of urinary tract	0.816	0.184
M19.99 Arthrosis, unspecified (Site unspecified)	0.815	0.185
S40-S49 Injuries to the shoulder and upper arm	0.815	0.185
I35 Nonrheumatic aortic valve disorders	0.812	0.188
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.811	0.189
I74 Arterial embolism and thrombosis	0.806	0.194
K72 Hepatic failure, not elsewhere classified	0.805	0.195
D14 Benign neoplasm of middle ear and respiratory system	0.805	0.195
K75 Other inflammatory liver diseases	0.803	0.197
G90-G99 Other disorders of the nervous system	0.803	0.197
I47.2 Ventricular tachycardia	0.802	0.198
L92 Granulomatous disorders of skin and subcutaneous tissue	0.802	0.198
D04 Carcinoma in situ of skin	0.801	0.199
C43 Malignant melanoma of skin	0.801	0.199
N20.1 Calculus of ureter	0.801	0.199
D26 Other benign neoplasms of uterus	0.800	0.200
Y57 Other and unspecified drugs and medicaments	0.799	0.201
K06 Other disorders of gingiva and edentulous alveolar ridge	0.798	0.202
K92 Other diseases of digestive system	0.798	0.202
S50-S59 Injuries to the elbow and forearm	0.798	0.202
D17.0 Benign lipomatous neoplasm of skin and subcutaneous tissue of head, face and neck	0.796	0.204
K07 Dentofacial anomalies [including malocclusion]	0.795	0.205
K04 Diseases of pulp and periapical tissues	0.795	0.205
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.793	0.207
I25 Chronic ischaemic heart disease	0.792	0.208
C15-C26 Malignant neoplasms of digestive organs	0.792	0.208
K65-K67 Diseases of peritoneum	0.791	0.208
C44.7 Skin of lower limb, including hip	0.791	0.209
G20-G26 Extrapyramidal and movement disorders	0.791	0.209
D23.6 Skin of upper limb, including shoulder	0.791	0.209
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.791	0.209
N18.4 Chronic kidney disease, stage 4	0.790	0.210
H53-H54 Visual disturbances and blindness	0.789	0.211
I24 Other acute ischaemic heart diseases	0.788	0.212
L43 Lichen planus	0.787	0.213
N94 Pain and other conditions associated with female genital organs and menstrual cycle	0.783	0.217
L83 Acanthosis nigricans	0.780	0.220
K26 Duodenal ulcer	0.778	0.222
L50 Urticaria	0.777	0.223
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.776	0.224
I72 Other aneurysm	0.774	0.226
E00-E07 Disorders of thyroid gland	0.773	0.227
N18.2 Chronic kidney disease, stage 2	0.773	0.227
D28 Benign neoplasm of other and unspecified female genital organs	0.772	0.228
I05-I09 Chronic rheumatic heart diseases	0.772	0.228
S80-S89 Injuries to the knee and lower leg	0.771	0.229
L98.8 Other specified disorders of skin and subcutaneous tissue	0.771	0.229
H55-H59 Other disorders of eye and adnexa	0.770	0.230
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.770	0.230
W20-W49 Exposure to inanimate mechanical forces	0.769	0.230
I25.9 Chronic ischaemic heart disease, unspecified	0.769	0.231
I36 Nonrheumatic tricuspid valve disorders	0.767	0.233
N99-N99 Other disorders of the genitourinary system	0.766	0.234
D06.9 Cervix, unspecified	0.766	0.234
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.766	0.234
I10 Essential (primary) hypertension	0.766	0.234
E10-E14 Diabetes mellitus	0.765	0.235
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.765	0.235
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.764	0.236
I47.9 Paroxysmal tachycardia, unspecified	0.764	0.236
V01-V09 Pedestrian injured in transport accident	0.763	0.237
N23 Unspecified renal colic	0.762	0.238
D18.0 Haemangioma, any site	0.762	0.238
G50-G59 Nerve, nerve root and plexus disorders	0.762	0.238
S72 Fracture of femur	0.760	0.240
L00-L08 Infections of the skin and subcutaneous tissue	0.759	0.241
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.759	0.241
V10-V19 Pedal cyclist injured in transport accident	0.757	0.243
D32 Benign neoplasm of meninges	0.757	0.243
W00-W19 Falls	0.756	0.244
I71.0 Dissection of aorta [any part]	0.755	0.245
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.754	0.246
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.748	0.252
Chapter XXII Codes for special purposes	0.747	0.253
D03 Melanoma in situ	0.747	0.253
S90-S99 Injuries to the ankle and foot	0.742	0.258
K51 Ulcerative colitis	0.742	0.258
D22.7 Melanocytic naevi of lower limb, including hip	0.740	0.260
D23.5 Skin of trunk	0.740	0.260
Chapter XV Pregnancy, childbirth and the puerperium	0.739	0.261
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.739	0.261
K52 Other non-infective gastro-enteritis and colitis	0.738	0.262
L93 Lupus erythematosus	0.737	0.263
I44 Atrioventricular and left bundle-branch block	0.737	0.263
D35 Benign neoplasm of other and unspecified endocrine glands	0.737	0.263
M19.0 Primary arthrosis of other joints	0.737	0.263
N86 Erosion and ectropion of cervix uteri	0.737	0.263
G99 Other disorders of nervous system in diseases classified elsewhere	0.736	0.264
N28 Other disorders of kidney and ureter, not elsewhere classified	0.735	0.265
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.735	0.265
N87 Dysplasia of cervix uteri	0.733	0.266
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.732	0.268
K04.6 Periapical abscess with sinus	0.731	0.269
E23 Hypofunction and other disorders of pituitary gland	0.730	0.270
N85 Other noninflammatory disorders of uterus, except cervix	0.730	0.270
K05 Gingivitis and periodontal diseases	0.730	0.270
X60-X84 Intentional self-harm	0.729	0.271
X20-X29 Contact with venomous animals and plants	0.728	0.272
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.728	0.272
K11 Diseases of salivary glands	0.726	0.274
E03 Other hypothyroidism	0.725	0.275
K50.9 Crohn's disease, unspecified	0.725	0.275
I77 Other disorders of arteries and arterioles	0.724	0.276
H46-H48 Disorders of optic nerve and visual pathways	0.723	0.277
N70-N77 Inflammatory diseases of female pelvic organs	0.723	0.277
N03 Chronic nephritic syndrome	0.723	0.277
X40-X49 Accidental poisoning by and exposure to noxious substances	0.722	0.278
D36 Benign neoplasm of other and unspecified sites	0.720	0.280
I70 Atherosclerosis	0.718	0.282
H53 Visual disturbances	0.718	0.282
K92.2 Gastro-intestinal haemorrhage, unspecified	0.718	0.282
D21 Other benign neoplasms of connective and other soft tissue	0.717	0.283
K12 Stomatitis and related lesions	0.717	0.283
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.717	0.283
C40-C41 Malignant neoplasms of bone and articular cartilage	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
L10-L14 Bullous disorders	0.717	0.283
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere	0.717	0.283
L95 Vasculitis limited to skin, not elsewhere classified	0.717	0.283
L94 Other localised connective tissue disorders	0.717	0.283
L87 Transepidermal elimination disorders	0.717	0.283
L88 Pyoderma gangrenosum	0.717	0.283
L86 Keratoderma in diseases classified elsewhere	0.717	0.283
L80 Vitiligo	0.717	0.283
C44.9 Malignant neoplasm of skin, unspecified	0.716	0.284
C44.8 Overlapping lesion of skin	0.716	0.284
D23.1 Skin of eyelid, including canthus	0.715	0.285
I00-I02 Acute rheumatic fever	0.715	0.285
D10.0 Lip	0.715	0.285
N90 Other noninflammatory disorders of vulva and perineum	0.715	0.285
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.715	0.285
L89 Decubitus ulcer	0.714	0.286
C44.5 Skin of trunk	0.713	0.287
I98 Other disorders of circulatory system in diseases classified elsewhere	0.713	0.287
D31 Benign neoplasm of eye and adnexa	0.712	0.288
D30 Benign neoplasm of urinary organs	0.712	0.288
D29 Benign neoplasm of male genital organs	0.712	0.288
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum	0.712	0.288
D19 Benign neoplasm of mesothelial tissue	0.712	0.288
D16 Benign neoplasm of bone and articular cartilage	0.712	0.288
D15 Benign neoplasm of other and unspecified intrathoracic organs	0.712	0.288
K13 Other diseases of lip and oral mucosa	0.712	0.288
N18.3 Chronic kidney disease, stage 3	0.711	0.289
D22.1 Melanocytic naevi of eyelid, including canthus	0.710	0.289
K76.6 Portal hypertension	0.710	0.290
K06.8 Other specified disorders of gingiva and edentulous alveolar ridge	0.710	0.290
I78 Diseases of capillaries	0.708	0.292
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.707	0.293
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.706	0.294
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.706	0.294
G20 Parkinson's disease	0.706	0.294
D22.6 Melanocytic naevi of upper limb, including shoulder	0.703	0.297
C21 Malignant neoplasm of anus and anal canal	0.703	0.297
K74.0 Hepatic fibrosis	0.703	0.297
K14 Diseases of tongue	0.703	0.297
L44 Other papulosquamous disorders	0.701	0.298
L41 Parapsoriasis	0.701	0.298
L45 Papulosquamous disorders in diseases classified elsewhere	0.701	0.298
L42 Pityriasis rosea	0.701	0.298
D34 Benign neoplasm of thyroid gland	0.701	0.299
D17.2 Benign lipomatous neoplasm of skin and subcutaneous tissue of limbs	0.699	0.301
D17.1 Benign lipomatous neoplasm of skin and subcutaneous tissue of trunk	0.699	0.301
G35-G37 Demyelinating diseases of the central nervous system	0.699	0.301
M19.98 Arthrosis, unspecified (Other)	0.698	0.302
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.698	0.302
I42 Cardiomyopathy	0.697	0.303
I44.0 Atrioventricular block, first degree	0.697	0.303
N18.0 End-stage renal disease	0.696	0.303
V20-V29 Motorcycle rider injured in transport accident	0.696	0.304
T66-T78 Other and unspecified effects of external causes	0.696	0.304
Y57.9 Drug or medicament, unspecified	0.695	0.305
N94.1 Dyspareunia	0.695	0.305
S10-S19 Injuries to the neck	0.694	0.306
L40.5 Arthropathic psoriasis	0.694	0.306
S20-S29 Injuries to the thorax	0.694	0.306
K76.9 Liver disease, unspecified	0.694	0.306
K92.0 Haematemesis	0.693	0.307
I46 Cardiac arrest	0.692	0.308
G56 Mononeuropathies of upper limb	0.691	0.309
E03.9 Hypothyroidism, unspecified	0.691	0.309
S42 Fracture of shoulder and upper arm	0.690	0.310
D10.1 Tongue	0.690	0.310
K77 Liver disorders in diseases classified elsewhere	0.690	0.310
K73 Chronic hepatitis, not elsewhere classified	0.690	0.310
K71 Toxic liver disease	0.690	0.310
M45-M49 Spondylopathies	0.690	0.310
D23.9 Skin, unspecified	0.688	0.312
C25 Malignant neoplasm of pancreas	0.688	0.312
N22 Calculus of urinary tract in diseases classified elsewhere	0.687	0.313
N89 Other noninflammatory disorders of vagina	0.687	0.313
K66 Other disorders of peritoneum	0.687	0.313
L91 Hypertrophic disorders of skin	0.687	0.313
M19.97 Arthrosis, unspecified (Ankle and foot)	0.686	0.314
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.686	0.314
N18.5 Chronic kidney disease, stage 5	0.686	0.314
L40.8 Other psoriasis	0.686	0.314
L40.4 Guttate psoriasis	0.686	0.314
L40.3 Pustulosis palmaris et plantaris	0.686	0.314
L40.2 Acrodermatitis continua	0.686	0.314
L40.1 Generalised pustular psoriasis	0.686	0.314
K76.0 Fatty (change of) liver, not elsewhere classified	0.686	0.314
E22 Hyperfunction of pituitary gland	0.685	0.315
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.684	0.316
Y35-Y36 Legal intervention and operations of war	0.684	0.316
Y10-Y34 Event of undetermined intent	0.684	0.316
Y00-Y09 Assault	0.684	0.316
X85-X99 Assault	0.684	0.316
X58-X59 Accidental exposure to other and unspecified factors	0.684	0.316
X50-X57 Overexertion, travel and privation	0.684	0.316
X30-X39 Exposure to forces of nature	0.684	0.316
X10-X19 Contact with heat and hot substances	0.684	0.316
X00-X09 Exposure to smoke, fire and flames	0.684	0.316
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.684	0.316
W75-W84 Other accidental threats to breathing	0.684	0.316
W65-W74 Accidental drowning and submersion	0.684	0.316
W50-W64 Exposure to animate mechanical forces	0.684	0.316
V98-V99 Other and unspecified transport accidents	0.684	0.316
V95-V97 Air and space transport accidents	0.684	0.316
V90-V94 Water transport accidents	0.684	0.316
V80-V89 Other land transport accidents	0.684	0.316
V70-V79 Bus occupant injured in transport accident	0.684	0.316
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.684	0.316
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.684	0.316
V40-V49 Car occupant injured in transport accident	0.684	0.316
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.684	0.316
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.683	0.317
I52 Other heart disorders in diseases classified elsewhere	0.682	0.318
I48 Atrial fibrillation and flutter	0.682	0.318
I43 Cardiomyopathy in diseases classified elsewhere	0.682	0.318
I41 Myocarditis in diseases classified elsewhere	0.682	0.318
I40 Acute myocarditis	0.682	0.318
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.682	0.318
I37 Pulmonary valve disorders	0.682	0.318
I32 Pericarditis in diseases classified elsewhere	0.682	0.318
D41.4 Bladder	0.682	0.318
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.682	0.318
G99.2 Myelopathy in diseases classified elsewhere	0.682	0.318
C43.7 Malignant melanoma of lower limb, including hip	0.681	0.319
D22.4 Melanocytic naevi of scalp and neck	0.681	0.319
N10-N16 Renal tubulo-interstitial diseases	0.681	0.319
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.681	0.319
I35.1 Aortic (valve) insufficiency	0.681	0.319
I30 Acute pericarditis	0.680	0.320
I24.8 Other forms of acute ischaemic heart disease	0.680	0.320
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.678	0.322
T33-T35 Frostbite	0.677	0.323
T26-T28 Burns and corrosions confined to eye and internal organs	0.677	0.323
T20-T25 Burns and corrosions of external body surface, specified by site	0.677	0.323
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.677	0.323
T00-T07 Injuries involving multiple body regions	0.677	0.323
L85 Other epidermal thickening	0.676	0.323
Y41 Other systemic anti-infectives and antiparasitics	0.676	0.324
K50.0 Crohn's disease of small intestine	0.675	0.325
E27 Other disorders of adrenal gland	0.675	0.325
D47.3 Essential (haemorrhagic) thrombocythaemia	0.674	0.326
N18.8 Other chronic renal failure	0.674	0.326
N18.1 Chronic kidney disease, stage 1	0.674	0.326
M19.90 Arthrosis, unspecified (Multiple sites)	0.674	0.326
I71.8 Aortic aneurysm of unspecified site, ruptured	0.674	0.326
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.674	0.326
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.674	0.326
I71.3 Abdominal aortic aneurysm, ruptured	0.674	0.326
I71.1 Thoracic aortic aneurysm, ruptured	0.674	0.326
L50.9 Urticaria, unspecified	0.674	0.326
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.672	0.327
D04.7 Skin of lower limb, including hip	0.672	0.328
S60-S69 Injuries to the wrist and hand	0.672	0.328
C67 Malignant neoplasm of bladder	0.672	0.328
K07.6 Temporomandibular joint disorders	0.671	0.328
T15-T19 Effects of foreign body entering through natural orifice	0.671	0.329
D22.9 Melanocytic naevi, unspecified	0.671	0.329
D22.2 Melanocytic naevi of ear and external auricular canal	0.671	0.329
D22.0 Melanocytic naevi of lip	0.671	0.329
K74.5 Biliary cirrhosis, unspecified	0.671	0.329
I33 Acute and subacute endocarditis	0.670	0.329
D14.0 Middle ear, nasal cavity and accessory sinuses	0.670	0.330
I38 Endocarditis, valve unspecified	0.670	0.330
I25.8 Other forms of chronic ischaemic heart disease	0.670	0.330
N20.9 Urinary calculus, unspecified	0.669	0.331
D09 Carcinoma in situ of other and unspecified sites	0.669	0.331
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.668	0.332
M80-M85 Disorders of bone density and structure	0.668	0.332
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.667	0.333
N17.0 Acute renal failure with tubular necrosis	0.667	0.333
E40-E46 Malnutrition	0.667	0.333
C51-C58 Malignant neoplasms of female genital organs	0.667	0.333
N02 Recurrent and persistent haematuria	0.666	0.333
N94.8 Other specified conditions associated with female genital organs and menstrual cycle	0.666	0.334
D17.3 Benign lipomatous neoplasm of skin and subcutaneous tissue of other and unspecified sites	0.666	0.334
Y40 Systemic antibiotics	0.666	0.334
D23.4 Skin of scalp and neck	0.665	0.335
N82 Fistulae involving female genital tract	0.664	0.336
D10.3 Other and unspecified parts of mouth	0.664	0.336
D23.3 Skin of other and unspecified parts of face	0.662	0.338
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.661	0.339
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.661	0.339
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.661	0.339
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.661	0.339
K03 Other diseases of hard tissues of teeth	0.661	0.339
K00 Disorders of tooth development and eruption	0.661	0.339
D02 Carcinoma in situ of middle ear and respiratory system	0.661	0.339
D01 Carcinoma in situ of other and unspecified digestive organs	0.661	0.339
D00 Carcinoma in situ of oral cavity, oesophagus and stomach	0.661	0.339
I34.9 Nonrheumatic mitral valve disorder, unspecified	0.660	0.340
I34.8 Other nonrheumatic mitral valve disorders	0.660	0.340
I34.2 Nonrheumatic mitral (valve) stenosis	0.660	0.340
M19.07 Primary arthrosis of other joints (Ankle and foot)	0.660	0.340
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.660	0.340
L53 Other erythematous conditions	0.658	0.341
L03 Cellulitis	0.658	0.342
S52 Fracture of forearm	0.657	0.343
M19.1 Posttraumatic arthrosis of other joints	0.657	0.343
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.657	0.343
D13 Benign neoplasm of other and ill-defined parts of digestive system	0.656	0.344
S72.1 Pertrochanteric fracture	0.656	0.344
I24.9 Acute ischaemic heart disease, unspecified	0.656	0.344
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.655	0.345
D23.2 Skin of ear and external auricular canal	0.655	0.345
D23.0 Skin of lip	0.655	0.345
G00-G09 Inflammatory diseases of the central nervous system	0.654	0.346
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.654	0.346
Y60-Y69 Misadventures to patients during surgical and medical care	0.654	0.346
E29 Testicular dysfunction	0.652	0.348
E28 Ovarian dysfunction	0.652	0.348
T79-T79 Certain early complications of trauma	0.651	0.349
C66 Malignant neoplasm of ureter	0.651	0.349
K50.1 Crohn's disease of large intestine	0.650	0.350
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.650	0.350
L43.9 Lichen planus, unspecified	0.650	0.350
K75.4 Autoimmune hepatitis	0.649	0.350
N28.8 Other specified disorders of kidney and ureter	0.650	0.350
Y51 Drugs primarily affecting the autonomic nervous system	0.649	0.350
D27 Benign neoplasm of ovary	0.649	0.351
N85.8 Other specified noninflammatory disorders of uterus	0.649	0.351
I47.1 Supraventricular tachycardia	0.649	0.351
H55 Nystagmus and other irregular eye movements	0.648	0.352
S50 Superficial injury of forearm	0.647	0.353
Y52 Agents primarily affecting the cardiovascular system	0.647	0.353
L81.8 Other specified disorders of pigmentation	0.647	0.353
L81.7 Pigmented purpuric dermatosis	0.647	0.353
L81.6 Other disorders of diminished melanin formation	0.647	0.353
L81.5 Leukoderma, not elsewhere classified	0.647	0.353
L81.3 Cafe au lait spots	0.647	0.353
L81.2 Freckles	0.647	0.353
L81.1 Chloasma	0.647	0.353
L81.0 Postinflammatory hyperpigmentation	0.647	0.353
K70 Alcoholic liver disease	0.646	0.353
K72.0 Acute and subacute hepatic failure	0.646	0.354
Y59 Other and unspecified vaccines and biological substances	0.645	0.355
Y58 Bacterial vaccines	0.645	0.355
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.645	0.355
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.645	0.355
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.645	0.355
Y53 Agents primarily affecting the gastro-intestinal system	0.645	0.355
Y50 Central nervous system stimulants, not elsewhere classified	0.645	0.355
Y49 Psychotropic drugs, not elsewhere classified	0.645	0.355
Y48 Anaesthetics and therapeutic gases	0.645	0.355
Y47 Sedatives, hypnotics and antianxiety drugs	0.645	0.355
Y46 Antiepileptics and anti-Parkinsonism drugs	0.645	0.355
D26.0 Cervix uteri	0.645	0.355
Y44 Agents primarily affecting blood constituents	0.645	0.355
K72.9 Hepatic failure, unspecified	0.645	0.355
C50-C50 Malignant neoplasm of breast	0.644	0.356
K26.9 Unspecified as acute or chronic, without haemorrhage or perforation	0.644	0.356
N90.7 Vulvar cyst	0.643	0.357
M18 Arthrosis of first carpometacarpal joint	0.643	0.357
N17.9 Acute renal failure, unspecified	0.642	0.358
N80 Endometriosis	0.642	0.358
M65-M68 Disorders of synovium and tendon	0.642	0.358
D33 Benign neoplasm of brain and other parts of central nervous system	0.641	0.359
Y57.5 X-ray contrast media	0.640	0.359
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.640	0.360
Chapter V Mental and behavioural disorders	0.640	0.360
M40-M43 Deforming dorsopathies	0.640	0.360
I35.2 Aortic (valve) stenosis with insufficiency	0.640	0.360
I47.0 Reentry ventricular arrhythmia	0.639	0.361
M00-M03 Infectious arthropathies	0.639	0.361
M19.94 Arthrosis, unspecified (Hand)	0.639	0.361
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.639	0.361
K04.8 Radicular cyst	0.638	0.362
T88 Other complications of surgical and medical care, not elsewhere classified	0.638	0.362
N87.1 Moderate cervical dysplasia	0.638	0.362
K10 Other diseases of jaws	0.638	0.362
M19.95 Arthrosis, unspecified (Pelvic region and thigh)	0.636	0.363
N08 Glomerular disorders in diseases classified elsewhere	0.635	0.365
D22.3 Melanocytic naevi of other and unspecified parts of face	0.635	0.365
Y42.7 Androgens and anabolic congeners	0.635	0.365
G51 Facial nerve disorders	0.634	0.366
I36.1 Nonrheumatic tricuspid (valve) insufficiency	0.634	0.366
M91-M94 Chondropathies	0.632	0.367
K09 Cysts of oral region, not elsewhere classified	0.632	0.368
D04.3 Skin of other and unspecified parts of face	0.631	0.369
K75.8 Other specified inflammatory liver diseases	0.631	0.369
E23.0 Hypopituitarism	0.630	0.370
K07.3 Anomalies of tooth position	0.630	0.370
L54 Erythema in diseases classified elsewhere	0.629	0.371
L51 Erythema multiforme	0.629	0.371
L52 Erythema nodosum	0.629	0.371
O20-O29 Other maternal disorders predominantly related to pregnancy	0.629	0.371
N98 Complications associated with artificial fertilisation	0.628	0.372
N91 Absent, scanty and rare menstruation	0.628	0.372
N96 Habitual aborter	0.628	0.372
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.627	0.373
K51.8 Other ulcerative colitis	0.627	0.373
N20.2 Calculus of kidney with calculus of ureter	0.627	0.373
H40-H42 Glaucoma	0.627	0.373
N26 Unspecified contracted kidney	0.627	0.373
C44.2 Skin of ear and external auricular canal	0.626	0.373
E11 Non-insulin-dependent diabetes mellitus	0.626	0.374
C21.0 Anus, unspecified	0.626	0.374
E14 Unspecified diabetes mellitus	0.626	0.374
V01 Pedestrian injured in collision with pedal cycle	0.626	0.374
H58 Other disorders of eye and adnexa in diseases classified elsewhere	0.625	0.375
N97 Female infertility	0.625	0.375
N03.9 Unspecified	0.624	0.376
L92.3 Foreign body granuloma of skin and subcutaneous tissue	0.624	0.376
D23.7 Skin of lower limb, including hip	0.624	0.376
N05 Unspecified nephritic syndrome	0.624	0.376
C43.4 Malignant melanoma of scalp and neck	0.624	0.376
S82 Fracture of lower leg, including ankle	0.624	0.376
L81.9 Disorder of pigmentation, unspecified	0.624	0.376
N95 Menopausal and other perimenopausal disorders	0.624	0.376
L50.0 Allergic urticaria	0.623	0.376

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations