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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs114218990
log Bayes Factor = 11.7934
Chromosome 1   position 48,501,029  (GRCh37) Explore rs114218990 on Ensembl!
Variant rs114218990 is part of Cluster X0053

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter VI Diseases of the nervous system
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.999 0.001 0.000
E11 Non-insulin-dependent diabetes mellitus
0.999 0.001 0.000
E10-E14 Diabetes mellitus
0.999 0.001 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.998 0.002 0.000
Chapter I Certain infectious and parasitic diseases
0.996 0.004 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.994 0.006 0.000
G40-G47 Episodic and paroxysmal disorders
0.993 0.007 0.000
E11.9 Without complications
0.992 0.008 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.989 0.011 0.000
Chapter XX External causes of morbidity and mortality
0.989 0.011 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.984 0.016 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.984 0.016 0.000
Chapter II Neoplasms
0.984 0.016 0.000
E11.3 With ophthalmic complications
0.977 0.023 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.974 0.026 0.000
D60-D64 Aplastic and other anaemias
0.972 0.028 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.968 0.032 0.000
E50-E64 Other nutritional deficiencies
0.968 0.032 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.965 0.035 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.959 0.041 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.955 0.045 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.949 0.051 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.949 0.051 0.000
M50-M54 Other dorsopathies
0.946 0.054 0.000
M70-M79 Other soft tissue disorders
0.946 0.054 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.944 0.056 0.000
Y40 Systemic antibiotics
0.943 0.057 0.000
Y57 Other and unspecified drugs and medicaments
0.941 0.059 0.000
G45.9 Transient cerebral ischaemic attack, unspecified
0.940 0.060 0.000
C44 Other malignant neoplasms of skin
0.937 0.063 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.932 0.068 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.931 0.069 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.930 0.070 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.929 0.071 0.000
M75 Shoulder lesions
0.927 0.073 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.924 0.076 0.000
C44.3 Skin of other and unspecified parts of face
0.922 0.078 0.000
L20-L30 Dermatitis and eczema
0.917 0.083 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.914 0.086 0.000
Q60-Q64 Congenital malformations of the urinary system
0.913 0.087 0.000
A30-A49 Other bacterial diseases
0.911 0.089 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.907 0.093 0.000
R41.0 Disorientation, unspecified
0.907 0.093 0.000
G35 Multiple sclerosis
0.906 0.094 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.902 0.098 0.000
L27 Dermatitis due to substances taken internally
0.896 0.104 0.000
A00-A09 Intestinal infectious diseases
0.894 0.106 0.000
Y40.0 Penicillins
0.892 0.108 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.889 0.111 0.000
D50-D53 Nutritional anaemias
0.889 0.111 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.883 0.117 0.000
Y57.9 Drug or medicament, unspecified
0.883 0.117 0.000
L27.0 Generalised skin eruption due to drugs and medicaments
0.881 0.119 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.879 0.121 0.000
B25-B34 Other viral diseases
0.878 0.122 0.000
T51 Toxic effect of alcohol
0.878 0.122 0.000
R94 Abnormal results of function studies
0.876 0.124 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.873 0.127 0.000
E11.4 With neurological complications
0.870 0.130 0.000
B35-B49 Mycoses
0.870 0.130 0.000
E61 Deficiency of other nutrient elements
0.869 0.131 0.000
D64 Other anaemias
0.867 0.132 0.000
M54 Dorsalgia
0.867 0.133 0.000
G47 Sleep disorders
0.864 0.136 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.862 0.138 0.000
G30-G32 Other degenerative diseases of the nervous system
0.860 0.140 0.000
E53 Deficiency of other B group vitamins
0.857 0.143 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.857 0.143 0.000
M20-M25 Other joint disorders
0.855 0.145 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.854 0.146 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.854 0.146 0.000
T51.0 Ethanol
0.854 0.146 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.850 0.150 0.000
Q60 Renal agenesis and other reduction defects of kidney
0.848 0.152 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.847 0.153 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.847 0.153 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.846 0.154 0.000
R25 Abnormal involuntary movements
0.845 0.155 0.000
G43 Migraine
0.844 0.156 0.000
M75.1 Rotator cuff syndrome
0.844 0.156 0.000
M75.3 Calcific tendinitis of shoulder
0.844 0.156 0.000
E11.2 With renal complications
0.840 0.160 0.000
R42 Dizziness and giddiness
0.839 0.161 0.000
D72 Other disorders of white blood cells
0.836 0.164 0.000
M40-M43 Deforming dorsopathies
0.834 0.166 0.000
L02.4 Cutaneous abscess, furuncle and carbuncle of limb
0.834 0.166 0.000
A40 Streptococcal septicaemia
0.833 0.167 0.000
R29.6 Tendency to fall, not elsewhere classified
0.832 0.168 0.000
Y43 Primarily systemic agents
0.831 0.169 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.828 0.172 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.828 0.172 0.000
C01 Malignant neoplasm of base of tongue
0.828 0.172 0.000
M91-M94 Chondropathies
0.827 0.173 0.000
Q80-Q89 Other congenital malformations
0.819 0.181 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.818 0.182 0.000
E13 Other specified diabetes mellitus
0.818 0.182 0.000
E40-E46 Malnutrition
0.817 0.183 0.000
D50 Iron deficiency anaemia
0.817 0.183 0.000
M51 Other intervertebral disk disorders
0.816 0.184 0.000
A04 Other bacterial intestinal infections
0.815 0.185 0.000
R93.4 Abnormal findings on diagnostic imaging of urinary organs
0.815 0.185 0.000
G45.8 Other transient cerebral ischaemic attacks and related syndromes
0.812 0.188 0.000
E55 Vitamin D deficiency
0.812 0.188 0.000
A41 Other septicaemia
0.808 0.192 0.000
D75 Other diseases of blood and blood-forming organs
0.808 0.192 0.000
M54.5 Low back pain
0.804 0.196 0.000
S32 Fracture of lumbar spine and pelvis
0.803 0.197 0.000
B91 Sequelae of poliomyelitis
0.802 0.198 0.000
Y57.5 X-ray contrast media
0.801 0.199 0.000
D61 Other aplastic anaemias
0.801 0.199 0.000
C44.5 Skin of trunk
0.800 0.200 0.000
D62 Acute posthaemorrhagic anaemia
0.800 0.200 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.799 0.201 0.000
E61.1 Iron deficiency
0.799 0.201 0.000
G90-G99 Other disorders of the nervous system
0.798 0.202 0.000
M86-M90 Other osteopathies
0.798 0.202 0.000
D50.9 Iron deficiency anaemia, unspecified
0.797 0.203 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.797 0.203 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.797 0.203 0.000
R93.8 Abnormal findings on diagnostic imaging of other specified body structures
0.795 0.205 0.000
M75.9 Shoulder lesion, unspecified
0.794 0.206 0.000
D64.9 Anaemia, unspecified
0.793 0.207 0.000
B50-B64 Protozoal diseases
0.791 0.209 0.000
Y40.9 Systemic antibiotic, unspecified
0.790 0.210 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.788 0.212 0.000
S60-S69 Injuries to the wrist and hand
0.788 0.212 0.000
C44.2 Skin of ear and external auricular canal
0.788 0.212 0.000
X20-X29 Contact with venomous animals and plants
0.787 0.213 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.787 0.213 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.786 0.214 0.000
W20-W49 Exposure to inanimate mechanical forces
0.785 0.215 0.000
M51.2 Other specified intervertebral disk displacement
0.784 0.216 0.000
M60-M63 Disorders of muscles
0.784 0.216 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.780 0.220 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.779 0.221 0.000
M45-M49 Spondylopathies
0.779 0.221 0.000
E53.8 Deficiency of other specified B group vitamins
0.778 0.222 0.000
G40 Epilepsy
0.778 0.222 0.000
Q60.0 Renal agenesis, unilateral
0.778 0.222 0.000
C50-C50 Malignant neoplasm of breast
0.777 0.223 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.777 0.223 0.000
G44 Other headache syndromes
0.776 0.223 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.774 0.226 0.000
C49 Malignant neoplasm of other connective and soft tissue
0.773 0.227 0.000
W50-W64 Exposure to animate mechanical forces
0.771 0.229 0.000
D72.8 Other specified disorders of white blood cells
0.770 0.230 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.765 0.235 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.763 0.237 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.763 0.237 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.763 0.237 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.763 0.237 0.000
D80-D89 Certain disorders involving the immune mechanism
0.761 0.239 0.000
Q63 Other congenital malformations of kidney
0.761 0.239 0.000
A80-A89 Viral infections of the central nervous system
0.760 0.240 0.000
C45 Mesothelioma
0.760 0.240 0.000
V40-V49 Car occupant injured in transport accident
0.759 0.241 0.000
T14 Injury of unspecified body region
0.757 0.243 0.000
A04.7 Enterocolitis due to Clostridium difficile
0.756 0.244 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.755 0.244 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.755 0.245 0.000
B37 Candidiasis
0.753 0.247 0.000
C34 Malignant neoplasm of bronchus and lung
0.753 0.247 0.000
L03 Cellulitis
0.752 0.248 0.000
C44.7 Skin of lower limb, including hip
0.751 0.249 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.750 0.250 0.000
R41.2 Retrograde amnesia
0.749 0.251 0.000
G43.9 Migraine, unspecified
0.749 0.251 0.000
B25 Cytomegaloviral disease
0.748 0.252 0.000
M75.5 Bursitis of shoulder
0.748 0.252 0.000
G47.3 Sleep apnoea
0.747 0.253 0.000
M31 Other necrotising vasculopathies
0.746 0.254 0.000
R93.1 Abnormal findings on diagnostic imaging of heart and coronary circulation
0.744 0.256 0.000
V20-V29 Motorcycle rider injured in transport accident
0.744 0.256 0.000
M35 Other systemic involvement of connective tissue
0.742 0.258 0.000
R94.5 Abnormal results of liver function studies
0.742 0.258 0.000
L40-L45 Papulosquamous disorders
0.742 0.258 0.000
B99-B99 Other infectious diseases
0.741 0.259 0.000
C07 Malignant neoplasm of parotid gland
0.741 0.259 0.000
E20-E35 Disorders of other endocrine glands
0.740 0.260 0.000
B65-B83 Helminthiases
0.739 0.261 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.739 0.261 0.000
G31.9 Degenerative disease of nervous system, unspecified
0.737 0.263 0.000
L23 Allergic contact dermatitis
0.735 0.265 0.000
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx
0.732 0.268 0.000
R94.4 Abnormal results of kidney function studies
0.731 0.269 0.000
Y43.4 Immunosuppressive agents
0.731 0.269 0.000
M25 Other joint disorders, not elsewhere classified
0.730 0.270 0.000
C32 Malignant neoplasm of larynx
0.730 0.270 0.000
C04 Malignant neoplasm of floor of mouth
0.729 0.271 0.000
D63.8 Anaemia in other chronic diseases classified elsewhere
0.728 0.272 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.727 0.273 0.000
C10 Malignant neoplasm of oropharynx
0.727 0.273 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.727 0.273 0.000
T63 Toxic effect of contact with venomous animals
0.727 0.273 0.000
R47-R49 Symptoms and signs involving speech and voice
0.726 0.274 0.000
C48 Malignant neoplasm of retroperitoneum and peritoneum
0.726 0.274 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.725 0.275 0.000
S68 Traumatic amputation of wrist and hand
0.725 0.275 0.000
E11.5 With peripheral circulatory complications
0.724 0.276 0.000
M43 Other deforming dorsopathies
0.722 0.278 0.000
C44.1 Skin of eyelid, including canthus
0.721 0.279 0.000
B37.8 Candidiasis of other sites
0.720 0.280 0.000
G63.2 Diabetic polyneuropathy
0.720 0.280 0.000
Q00-Q07 Congenital malformations of the nervous system
0.719 0.281 0.000
X50-X57 Overexertion, travel and privation
0.719 0.281 0.000
C09 Malignant neoplasm of tonsil
0.718 0.281 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
E11.8 With unspecified complications
0.716 0.284 0.000
E11.7 With multiple complications
0.716 0.284 0.000
E11.0 With coma
0.716 0.284 0.000
E12 Malnutrition-related diabetes mellitus
0.716 0.284 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.716 0.284 0.000
D55-D59 Haemolytic anaemias
0.715 0.285 0.000
R45 Symptoms and signs involving emotional state
0.715 0.285 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.715 0.285 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.714 0.286 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.714 0.286 0.000
A75-A79 Rickettsioses
0.714 0.286 0.000
A70-A74 Other diseases caused by chlamydiae
0.714 0.286 0.000
A65-A69 Other spirochaetal diseases
0.714 0.286 0.000
A20-A28 Certain zoonotic bacterial diseases
0.714 0.286 0.000
A15-A19 Tuberculosis
0.714 0.286 0.000
D75.1 Secondary polycythaemia
0.713 0.287 0.000
A41.5 Septicaemia due to other Gram-negative organisms
0.713 0.287 0.000
S90-S99 Injuries to the ankle and foot
0.712 0.288 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.712 0.288 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.712 0.288 0.000
G41 Status epilepticus
0.712 0.288 0.000
M54.59 Low back pain (Site unspecified)
0.712 0.288 0.000
E11.6 With other specified complications
0.711 0.288 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.710 0.290 0.000
S10-S19 Injuries to the neck
0.710 0.290 0.000
T79-T79 Certain early complications of trauma
0.710 0.290 0.000
M00-M03 Infectious arthropathies
0.709 0.291 0.000
Y35-Y36 Legal intervention and operations of war
0.709 0.291 0.000
Y10-Y34 Event of undetermined intent
0.709 0.291 0.000
Y00-Y09 Assault
0.709 0.291 0.000
X85-X99 Assault
0.709 0.291 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.709 0.291 0.000
X30-X39 Exposure to forces of nature
0.709 0.291 0.000
X10-X19 Contact with heat and hot substances
0.709 0.291 0.000
X00-X09 Exposure to smoke, fire and flames
0.709 0.291 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.709 0.291 0.000
W75-W84 Other accidental threats to breathing
0.709 0.291 0.000
W65-W74 Accidental drowning and submersion
0.709 0.291 0.000
V98-V99 Other and unspecified transport accidents
0.709 0.291 0.000
V95-V97 Air and space transport accidents
0.709 0.291 0.000
V90-V94 Water transport accidents
0.709 0.291 0.000
V70-V79 Bus occupant injured in transport accident
0.709 0.291 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.709 0.291 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.709 0.291 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.709 0.291 0.000
V01-V09 Pedestrian injured in transport accident
0.709 0.291 0.000
G47.9 Sleep disorder, unspecified
0.709 0.291 0.000
M75.0 Adhesive capsulitis of shoulder
0.708 0.292 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.708 0.292 0.000
L05 Pilonidal cyst
0.707 0.293 0.000
E11.1 With ketoacidosis
0.706 0.294 0.000
G70-G73 Diseases of myoneural junction and muscle
0.706 0.294 0.000
V80-V89 Other land transport accidents
0.706 0.294 0.000
R92 Abnormal findings on diagnostic imaging of breast
0.706 0.294 0.000
Y59 Other and unspecified vaccines and biological substances
0.705 0.294 0.000
Y58 Bacterial vaccines
0.705 0.294 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.705 0.294 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.705 0.294 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.705 0.294 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.705 0.294 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.705 0.294 0.000
Y48 Anaesthetics and therapeutic gases
0.705 0.294 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.705 0.294 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.705 0.294 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.705 0.295 0.000
R25.8 Other and unspecified abnormal involuntary movements
0.705 0.295 0.000
X60-X84 Intentional self-harm
0.705 0.295 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.704 0.295 0.000
M53 Other dorsopathies, not elsewhere classified
0.704 0.296 0.000
M50 Cervical disk disorders
0.704 0.296 0.000
A40.3 Septicaemia due to Streptococcus pneumoniae
0.703 0.297 0.000
Chapter VII Diseases of the eye and adnexa
0.702 0.298 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.702 0.298 0.000
M54.57 Low back pain (Lumbosacral region)
0.701 0.299 0.000
R25.2 Cramp and spasm
0.700 0.300 0.000
E55.9 Vitamin D deficiency, unspecified
0.700 0.300 0.000
R79 Other abnormal findings of blood chemistry
0.699 0.301 0.000
T93 Sequelae of injuries of lower limb
0.698 0.302 0.000
T33-T35 Frostbite
0.698 0.302 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.698 0.302 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.698 0.302 0.000
T00-T07 Injuries involving multiple body regions
0.698 0.302 0.000
M54.1 Radiculopathy
0.698 0.302 0.000
M54.8 Other dorsalgia
0.697 0.303 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.697 0.303 0.000
A40.0 Septicaemia due to streptococcus, group A
0.696 0.304 0.000
R46 Symptoms and signs involving appearance and behaviour
0.694 0.306 0.000
R43 Disturbances of smell and taste
0.694 0.306 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.694 0.306 0.000
E63 Other nutritional deficiencies
0.694 0.306 0.000
E56 Other vitamin deficiencies
0.694 0.306 0.000
E51 Thiamine deficiency
0.694 0.306 0.000
E50 Vitamin A deficiency
0.694 0.306 0.000
E60 Dietary zinc deficiency
0.694 0.306 0.000
E59 Dietary selenium deficiency
0.694 0.306 0.000
E58 Dietary calcium deficiency
0.694 0.306 0.000
E54 Ascorbic acid deficiency
0.694 0.306 0.000
E52 Niacin deficiency [pellagra]
0.694 0.306 0.000
M93 Other osteochondropathies
0.693 0.307 0.000
T14.0 Superficial injury of unspecified body region
0.692 0.308 0.000
B35 Dermatophytosis
0.692 0.308 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.692 0.308 0.000
Q35-Q37 Cleft lip and cleft palate
0.692 0.308 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.692 0.308 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.691 0.309 0.000
Q60.2 Renal agenesis, unspecified
0.691 0.309 0.000
S70-S79 Injuries to the hip and thigh
0.691 0.309 0.000
M89 Other disorders of bone
0.690 0.310 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.689 0.311 0.000
G45.2 Multiple and bilateral precerebral artery syndromes
0.688 0.312 0.000
G45.1 Carotid artery syndrome (hemispheric)
0.688 0.312 0.000
G45.0 Vertebro-basilar artery syndrome
0.688 0.312 0.000
E13.9 Without complications
0.688 0.312 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.687 0.313 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.687 0.313 0.000
E46 Unspecified protein-energy malnutrition
0.686 0.313 0.000
M25.7 Osteophyte
0.686 0.314 0.000
D53 Other nutritional anaemias
0.685 0.315 0.000
Y44 Agents primarily affecting blood constituents
0.684 0.316 0.000
M76 Enthesopathies of lower limb, excluding foot
0.684 0.316 0.000
B27 Infectious mononucleosis
0.683 0.317 0.000
Q87 Other specified congenital malformation syndromes affecting multiple systems
0.683 0.317 0.000
M75.2 Bicipital tendinitis
0.682 0.318 0.000
C51-C58 Malignant neoplasms of female genital organs
0.681 0.319 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.681 0.319 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.681 0.319 0.000
M31.6 Other giant cell arteritis
0.681 0.319 0.000
C13 Malignant neoplasm of hypopharynx
0.680 0.319 0.000
C11 Malignant neoplasm of nasopharynx
0.680 0.319 0.000
C08 Malignant neoplasm of other and unspecified major salivary glands
0.680 0.319 0.000
C06 Malignant neoplasm of other and unspecified parts of mouth
0.680 0.319 0.000
C05 Malignant neoplasm of palate
0.680 0.319 0.000
C03 Malignant neoplasm of gum
0.680 0.319 0.000
C00 Malignant neoplasm of lip
0.680 0.319 0.000
C12 Malignant neoplasm of pyriform sinus
0.680 0.319 0.000
L10-L14 Bullous disorders
0.680 0.320 0.000
S68.1 Traumatic amputation of other single finger (complete)(partial)
0.679 0.321 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.679 0.321 0.000
D61.9 Aplastic anaemia, unspecified
0.678 0.322 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.678 0.322 0.000
M21 Other acquired deformities of limbs
0.678 0.322 0.000
G01 Meningitis in bacterial diseases classified elsewhere
0.678 0.322 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.678 0.322 0.000
G36 Other acute disseminated demyelination
0.677 0.323 0.000
M77 Other enthesopathies
0.677 0.323 0.000
B15-B19 Viral hepatitis
0.677 0.323 0.000
G47.4 Narcolepsy and cataplexy
0.677 0.323 0.000
C49.2 Connective and soft tissue of lower limb, including hip
0.677 0.323 0.000
C02.9 Tongue, unspecified
0.677 0.323 0.000
Y40.7 Antifungal antibiotics, systemically used
0.676 0.324 0.000
Y40.6 Rifamycins
0.676 0.324 0.000
Y40.5 Aminoglycosides
0.676 0.324 0.000
Y40.4 Tetracyclines
0.676 0.324 0.000
Y40.3 Macrolides
0.676 0.324 0.000
Y40.2 Chloramphenicol group
0.676 0.324 0.000
Y40.1 Cefalosporins and other -lactam antibiotics
0.676 0.324 0.000
Y40.8 Other systemic antibiotics
0.676 0.324 0.000
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness
0.675 0.325 0.000
R50-R69 General symptoms and signs
0.675 0.325 0.000
L03.9 Cellulitis, unspecified
0.675 0.325 0.000
Y57.8 Other drugs and medicaments
0.675 0.325 0.000
Y57.7 Vitamins, not elsewhere classified
0.675 0.325 0.000
Y57.6 Other diagnostic agents
0.675 0.325 0.000
Y57.4 Pharmaceutical excipients
0.675 0.325 0.000
Y57.3 Alcohol deterrents
0.675 0.325 0.000
Y57.2 Antidotes and chelating agents, not elsewhere classified
0.675 0.325 0.000
Y57.1 Lipotropic drugs
0.675 0.325 0.000
Y57.0 Appetite depressants [anorectics]
0.675 0.325 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.675 0.325 0.000
D70 Agranulocytosis
0.674 0.326 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.673 0.327 0.000
M47 Spondylosis
0.673 0.327 0.000
C44.9 Malignant neoplasm of skin, unspecified
0.672 0.328 0.000
C44.8 Overlapping lesion of skin
0.672 0.328 0.000
B34 Viral infection of unspecified site
0.672 0.328 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.672 0.328 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.671 0.328 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.671 0.328 0.000
S50-S59 Injuries to the elbow and forearm
0.670 0.330 0.000
G37 Other demyelinating diseases of central nervous system
0.670 0.330 0.000
D45 Polycythaemia vera
0.670 0.330 0.000
Chapter XXII Codes for special purposes
0.669 0.331 0.000
L02.3 Cutaneous abscess, furuncle and carbuncle of buttock
0.669 0.331 0.000
Y52 Agents primarily affecting the cardiovascular system
0.668 0.332 0.000
R25.1 Tremor, unspecified
0.668 0.332 0.000
R41.1 Anterograde amnesia
0.667 0.333 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.666 0.333 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.666 0.333 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.666 0.333 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.666 0.333 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.666 0.333 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.666 0.333 0.000
T36 Poisoning by systemic antibiotics
0.666 0.333 0.000
M22 Disorders of patella
0.666 0.333 0.000
D74 Methaemoglobinaemia
0.666 0.334 0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.666 0.334 0.000
D71 Functional disorders of polymorphonuclear neutrophils
0.666 0.334 0.000
R93.3 Abnormal findings on diagnostic imaging of other parts of digestive tract
0.665 0.335 0.000
D63.0 Anaemia in neoplastic disease
0.665 0.335 0.000
M75.8 Other shoulder lesions
0.665 0.335 0.000
A04.8 Other specified bacterial intestinal infections
0.664 0.336 0.000
T43.2 Other and unspecified antidepressants
0.664 0.336 0.000
T65 Toxic effect of other and unspecified substances
0.663 0.337 0.000
T62 Toxic effect of other noxious substances eaten as food
0.663 0.337 0.000
T61 Toxic effect of noxious substances eaten as seafood
0.663 0.337 0.000
T60 Toxic effect of pesticides
0.663 0.337 0.000
T59 Toxic effect of other gases, fumes and vapours
0.663 0.337 0.000
T57 Toxic effect of other inorganic substances
0.663 0.337 0.000
T56 Toxic effect of metals
0.663 0.337 0.000
T54 Toxic effect of corrosive substances
0.663 0.337 0.000
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone
0.663 0.337 0.000
T52 Toxic effect of organic solvents
0.663 0.337 0.000
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants
0.663 0.337 0.000
T58 Toxic effect of carbon monoxide
0.663 0.337 0.000
T55 Toxic effect of soaps and detergents
0.663 0.337 0.000
D52 Folate deficiency anaemia
0.661 0.339 0.000
Q61 Cystic kidney disease
0.661 0.339 0.000
G08 Intracranial and intraspinal phlebitis and thrombophlebitis
0.660 0.340 0.000
L50-L54 Urticaria and erythema
0.660 0.340 0.000
Q50-Q56 Congenital malformations of genital organs
0.660 0.340 0.000
A40.9 Streptococcal septicaemia, unspecified
0.659 0.341 0.000
C43 Malignant melanoma of skin
0.658 0.342 0.000
L28 Lichen simplex chronicus and prurigo
0.658 0.342 0.000
L25 Unspecified contact dermatitis
0.658 0.342 0.000
L24 Irritant contact dermatitis
0.658 0.342 0.000
L21 Seborrhoeic dermatitis
0.658 0.342 0.000
L20 Atopic dermatitis
0.658 0.342 0.000
L26 Exfoliative dermatitis
0.658 0.342 0.000
L22 Diaper [napkin] dermatitis
0.658 0.342 0.000
G60 Hereditary and idiopathic neuropathy
0.657 0.343 0.000
R53 Malaise and fatigue
0.657 0.343 0.000
S32.1 Fracture of sacrum
0.656 0.343 0.000
R93.6 Abnormal findings on diagnostic imaging of limbs
0.655 0.345 0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)
0.655 0.345 0.000
H18 Other disorders of cornea
0.655 0.345 0.000
B25.9 Cytomegaloviral disease, unspecified
0.655 0.345 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.655 0.345 0.000
G00 Bacterial meningitis, not elsewhere classified
0.655 0.345 0.000
Q64 Other congenital malformations of urinary system
0.654 0.345 0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter
0.654 0.345 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.654 0.346 0.000
A48 Other bacterial diseases, not elsewhere classified
0.653 0.346 0.000
A44 Bartonellosis
0.653 0.346 0.000
A43 Nocardiosis
0.653 0.346 0.000
A42 Actinomycosis
0.653 0.346 0.000
A39 Meningococcal infection
0.653 0.346 0.000
A37 Whooping cough
0.653 0.346 0.000
A36 Diphtheria
0.653 0.346 0.000
A32 Listeriosis
0.653 0.346 0.000
A31 Infection due to other mycobacteria
0.653 0.346 0.000
A30 Leprosy [Hansen's disease]
0.653 0.346 0.000
A38 Scarlet fever
0.653 0.346 0.000
A35 Other tetanus
0.653 0.346 0.000
A34 Obstetrical tetanus
0.653 0.346 0.000
A33 Tetanus neonatorum
0.653 0.346 0.000
M45 Ankylosing spondylitis
0.653 0.347 0.000
Y42.7 Androgens and anabolic congeners
0.653 0.347 0.000
W44 Foreign body entering into or through eye or natural orifice
0.652 0.348 0.000
M24 Other specific joint derangements
0.652 0.348 0.000
Q63.0 Accessory kidney
0.652 0.348 0.000
E27 Other disorders of adrenal gland
0.651 0.349 0.000
C47 Malignant neoplasm of peripheral nerves and autonomic nervous system
0.651 0.349 0.000
C46 Kaposi's sarcoma
0.651 0.349 0.000
R90.0 Intracranial space-occupying lesion
0.650 0.350 0.000
C45.0 Mesothelioma of pleura
0.650 0.350 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.650 0.350 0.000
S32.3 Fracture of ilium
0.648 0.352 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.648 0.352 0.000
S40-S49 Injuries to the shoulder and upper arm
0.648 0.352 0.000
M80-M85 Disorders of bone density and structure
0.648 0.352 0.000
M25.8 Other specified joint disorders
0.647 0.353 0.000
R93.5 Abnormal findings on diagnostic imaging of other abdominal regions, including retroperitoneum
0.647 0.353 0.000
M35.3 Polymyalgia rheumatica
0.647 0.353 0.000
R40 Somnolence, stupor and coma
0.647 0.353 0.000
Q82 Other congenital malformations of skin
0.647 0.353 0.000
L04 Acute lymphadenitis
0.647 0.353 0.000
L01 Impetigo
0.647 0.353 0.000
L00 Staphylococcal scalded skin syndrome
0.647 0.353 0.000
R71 Abnormality of red blood cells
0.646 0.354 0.000
T91 Sequelae of injuries of neck and trunk
0.646 0.354 0.000
G45.3 Amaurosis fugax
0.646 0.354 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.646 0.354 0.000
R73 Elevated blood glucose level
0.644 0.356 0.000
B59 Pneumocystosis
0.643 0.357 0.000
L27.9 Dermatitis due to unspecified substance taken internally
0.643 0.357 0.000
L27.8 Dermatitis due to other substances taken internally
0.643 0.357 0.000
L27.2 Dermatitis due to ingested food
0.643 0.357 0.000
L27.1 Localised skin eruption due to drugs and medicaments
0.643 0.357 0.000
M71 Other bursopathies
0.642 0.357 0.000
X23 Contact with hornets, wasps and bees
0.642 0.357 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.642 0.358 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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