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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs114333031
log Bayes Factor = 14.2987
Chromosome 4   position 54,774,510  (GRCh37) Explore rs114333031 on Ensembl!
Variant rs114333031 is part of Cluster X0247

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E10-E14 Diabetes mellitus
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
E11 Non-insulin-dependent diabetes mellitus
1.000 0.000 0.000
I30-I52 Other forms of heart disease
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
0.999 0.001 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.999 0.001 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.999 0.001 0.000
E11.9 Without complications
0.998 0.002 0.000
I50 Heart failure
0.997 0.003 0.000
M20-M25 Other joint disorders
0.997 0.003 0.000
Chapter VI Diseases of the nervous system
0.993 0.007 0.000
Chapter II Neoplasms
0.991 0.009 0.000
E10 Insulin-dependent diabetes mellitus
0.989 0.011 0.000
M23 Internal derangement of knee
0.984 0.016 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.980 0.020 0.000
E10.9 Without complications
0.979 0.021 0.000
I50.9 Heart failure, unspecified
0.979 0.021 0.000
E11.3 With ophthalmic complications
0.977 0.023 0.000
M23.3 Other meniscus derangements
0.974 0.026 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.972 0.028 0.000
Chapter VIII Diseases of the ear and mastoid process
0.970 0.030 0.000
S60-S69 Injuries to the wrist and hand
0.961 0.039 0.000
M24 Other specific joint derangements
0.961 0.039 0.000
I50.0 Congestive heart failure
0.960 0.040 0.000
I49 Other cardiac arrhythmias
0.957 0.043 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.955 0.045 0.000
M25 Other joint disorders, not elsewhere classified
0.955 0.045 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.953 0.047 0.000
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.953 0.047 0.000
E20-E35 Disorders of other endocrine glands
0.952 0.048 0.000
D00-D09 In situ neoplasms
0.949 0.051 0.000
H65-H75 Diseases of middle ear and mastoid
0.944 0.056 0.000
Chapter I Certain infectious and parasitic diseases
0.943 0.057 0.000
E65-E68 Obesity and other hyperalimentation
0.934 0.066 0.000
I34 Nonrheumatic mitral valve disorders
0.930 0.070 0.000
G56 Mononeuropathies of upper limb
0.928 0.072 0.000
C79 Secondary malignant neoplasm of other sites
0.923 0.077 0.000
M25.7 Osteophyte
0.921 0.079 0.000
I47 Paroxysmal tachycardia
0.917 0.083 0.000
M24.1 Other articular cartilage disorders
0.914 0.086 0.000
I49.3 Ventricular premature depolarisation
0.913 0.087 0.000
Chapter XX External causes of morbidity and mortality
0.913 0.087 0.000
M05-M14 Inflammatory polyarthropathies
0.912 0.088 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.912 0.088 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.902 0.098 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.901 0.099 0.000
G56.0 Carpal tunnel syndrome
0.901 0.099 0.000
M23.8 Other internal derangements of knee
0.900 0.100 0.000
G20-G26 Extrapyramidal and movement disorders
0.897 0.103 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.896 0.104 0.000
M25.77 Osteophyte (Ankle and foot)
0.893 0.107 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.891 0.109 0.000
H60-H62 Diseases of external ear
0.890 0.110 0.000
I47.2 Ventricular tachycardia
0.889 0.111 0.000
I10-I15 Hypertensive diseases
0.886 0.114 0.000
E66 Obesity
0.886 0.114 0.000
S68 Traumatic amputation of wrist and hand
0.879 0.121 0.000
M86-M90 Other osteopathies
0.873 0.127 0.000
E14 Unspecified diabetes mellitus
0.868 0.132 0.000
E22 Hyperfunction of pituitary gland
0.867 0.133 0.000
G57 Mononeuropathies of lower limb
0.865 0.135 0.000
E66.9 Obesity, unspecified
0.863 0.137 0.000
E11.4 With neurological complications
0.863 0.137 0.000
H74 Other disorders of middle ear and mastoid
0.862 0.138 0.000
D05 Carcinoma in situ of breast
0.861 0.139 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.859 0.141 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.855 0.145 0.000
I49.8 Other specified cardiac arrhythmias
0.854 0.146 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.852 0.148 0.000
M24.16 Other articular cartilage disorders (Lower leg)
0.850 0.150 0.000
M13 Other arthritis
0.846 0.154 0.000
Q60-Q64 Congenital malformations of the urinary system
0.846 0.154 0.000
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)
0.842 0.158 0.000
B95-B98 Bacterial, viral and other infectious agents
0.840 0.160 0.000
I34.0 Mitral (valve) insufficiency
0.835 0.165 0.000
E16 Other disorders of pancreatic internal secretion
0.831 0.169 0.000
E70-E90 Metabolic disorders
0.830 0.170 0.000
T40.2 Other opioids
0.828 0.172 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.827 0.173 0.000
I36 Nonrheumatic tricuspid valve disorders
0.824 0.176 0.000
E23 Hypofunction and other disorders of pituitary gland
0.824 0.176 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.822 0.178 0.000
S68.1 Traumatic amputation of other single finger (complete)(partial)
0.821 0.179 0.000
S10-S19 Injuries to the neck
0.820 0.180 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.818 0.182 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.817 0.183 0.000
I46 Cardiac arrest
0.816 0.184 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.811 0.189 0.000
G50 Disorders of trigeminal nerve
0.811 0.189 0.000
G25 Other extrapyramidal and movement disorders
0.811 0.189 0.000
I50.1 Left ventricular failure
0.811 0.189 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.811 0.189 0.000
O60-O75 Complications of labour and delivery
0.807 0.193 0.000
H61 Other disorders of external ear
0.805 0.195 0.000
M23.83 Other internal derangements of knee (Medial collateral ligament or Other and unspecified medial meniscus)
0.804 0.196 0.000
M23.39 Other meniscus derangements (Unspecified ligament or Unspecified meniscus)
0.803 0.197 0.000
I38 Endocarditis, valve unspecified
0.803 0.197 0.000
T51 Toxic effect of alcohol
0.802 0.198 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.802 0.198 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.802 0.198 0.000
H70 Mastoiditis and related conditions
0.802 0.198 0.000
I33 Acute and subacute endocarditis
0.799 0.201 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.799 0.201 0.000
C15-C26 Malignant neoplasms of digestive organs
0.798 0.202 0.000
H74.4 Polyp of middle ear
0.798 0.202 0.000
C60-C63 Malignant neoplasms of male genital organs
0.798 0.202 0.000
H65 Nonsuppurative otitis media
0.796 0.204 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.796 0.204 0.000
E11.5 With peripheral circulatory complications
0.796 0.204 0.000
W20-W49 Exposure to inanimate mechanical forces
0.795 0.205 0.000
I34.1 Mitral (valve) prolapse
0.794 0.206 0.000
Q80-Q89 Other congenital malformations
0.793 0.207 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.792 0.208 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.791 0.209 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.791 0.209 0.000
D05.1 Intraductal carcinoma in situ
0.790 0.210 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.790 0.210 0.000
M13.9 Arthritis, unspecified
0.789 0.211 0.000
E86 Volume depletion
0.789 0.211 0.000
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.787 0.213 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.786 0.214 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.785 0.215 0.000
D06 Carcinoma in situ of cervix uteri
0.784 0.216 0.000
M65-M68 Disorders of synovium and tendon
0.783 0.217 0.000
E11.2 With renal complications
0.782 0.218 0.000
H66 Suppurative and unspecified otitis media
0.782 0.218 0.000
E16.2 Hypoglycaemia, unspecified
0.780 0.220 0.000
E10.4 With neurological complications
0.780 0.220 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.778 0.222 0.000
I10 Essential (primary) hypertension
0.777 0.223 0.000
M31 Other necrotising vasculopathies
0.776 0.224 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.776 0.224 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.776 0.224 0.000
M25.71 Osteophyte (Shoulder region)
0.775 0.225 0.000
M25.76 Osteophyte (Lower leg)
0.775 0.225 0.000
G57.6 Lesion of plantar nerve
0.775 0.225 0.000
E29 Testicular dysfunction
0.774 0.225 0.000
I20-I25 Ischaemic heart diseases
0.773 0.227 0.000
S90-S99 Injuries to the ankle and foot
0.772 0.228 0.000
D03 Melanoma in situ
0.772 0.228 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.770 0.230 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.768 0.232 0.000
S00-S09 Injuries to the head
0.768 0.232 0.000
E14.9 Without complications
0.768 0.232 0.000
T58 Toxic effect of carbon monoxide
0.766 0.234 0.000
E50-E64 Other nutritional deficiencies
0.766 0.234 0.000
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)
0.765 0.235 0.000
Q21 Congenital malformations of cardiac septa
0.765 0.235 0.000
S62 Fracture at wrist and hand level
0.764 0.236 0.000
M21 Other acquired deformities of limbs
0.763 0.237 0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.762 0.238 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.762 0.238 0.000
Q61 Cystic kidney disease
0.761 0.239 0.000
T79-T79 Certain early complications of trauma
0.760 0.240 0.000
G25.8 Other specified extrapyramidal and movement disorders
0.760 0.240 0.000
I49.0 Ventricular fibrillation and flutter
0.759 0.241 0.000
M60-M63 Disorders of muscles
0.759 0.241 0.000
G54 Nerve root and plexus disorders
0.758 0.242 0.000
M24.13 Other articular cartilage disorders (Forearm)
0.755 0.245 0.000
B15-B19 Viral hepatitis
0.755 0.245 0.000
G58 Other mononeuropathies
0.754 0.246 0.000
G56.8 Other mononeuropathies of upper limb
0.754 0.246 0.000
I05-I09 Chronic rheumatic heart diseases
0.752 0.248 0.000
I21 Acute myocardial infarction
0.751 0.249 0.000
C32 Malignant neoplasm of larynx
0.751 0.249 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.750 0.250 0.000
H61.0 Perichondritis of external ear
0.750 0.250 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.749 0.251 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.747 0.253 0.000
I49.1 Atrial premature depolarisation
0.746 0.254 0.000
G63.2 Diabetic polyneuropathy
0.746 0.254 0.000
E10.1 With ketoacidosis
0.744 0.256 0.000
M80-M85 Disorders of bone density and structure
0.743 0.257 0.000
M13.97 Arthritis, unspecified (Ankle and foot)
0.742 0.258 0.000
S20-S29 Injuries to the thorax
0.742 0.258 0.000
E10.5 With peripheral circulatory complications
0.742 0.258 0.000
E11.1 With ketoacidosis
0.742 0.258 0.000
E11.6 With other specified complications
0.742 0.258 0.000
S70-S79 Injuries to the hip and thigh
0.740 0.260 0.000
M23.31 Other meniscus derangements (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.740 0.260 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.740 0.260 0.000
G24 Dystonia
0.739 0.261 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.739 0.261 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.739 0.261 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.738 0.262 0.000
T40.4 Other synthetic narcotics
0.737 0.263 0.000
A00-A09 Intestinal infectious diseases
0.735 0.265 0.000
G62 Other polyneuropathies
0.735 0.265 0.000
V10-V19 Pedal cyclist injured in transport accident
0.733 0.267 0.000
M10 Gout
0.732 0.268 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.730 0.270 0.000
C51-C58 Malignant neoplasms of female genital organs
0.730 0.270 0.000
C25 Malignant neoplasm of pancreas
0.728 0.272 0.000
S60 Superficial injury of wrist and hand
0.728 0.272 0.000
O66 Other obstructed labour
0.727 0.273 0.000
M50-M54 Other dorsopathies
0.726 0.274 0.000
E22.0 Acromegaly and pituitary gigantism
0.724 0.276 0.000
E34 Other endocrine disorders
0.724 0.276 0.000
E23.0 Hypopituitarism
0.724 0.276 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.723 0.277 0.000
M45-M49 Spondylopathies
0.722 0.278 0.000
M91-M94 Chondropathies
0.722 0.278 0.000
Q50-Q56 Congenital malformations of genital organs
0.721 0.279 0.000
H60 Otitis externa
0.721 0.279 0.000
M00-M03 Infectious arthropathies
0.720 0.279 0.000
I46.0 Cardiac arrest with successful resuscitation
0.720 0.280 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.719 0.281 0.000
S64 Injury of nerves at wrist and hand level
0.718 0.282 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
E11.8 With unspecified complications
0.717 0.283 0.000
E11.7 With multiple complications
0.717 0.283 0.000
E11.0 With coma
0.717 0.283 0.000
I52 Other heart disorders in diseases classified elsewhere
0.717 0.283 0.000
I48 Atrial fibrillation and flutter
0.717 0.283 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.717 0.283 0.000
I41 Myocarditis in diseases classified elsewhere
0.717 0.283 0.000
I40 Acute myocarditis
0.717 0.283 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.717 0.283 0.000
I37 Pulmonary valve disorders
0.717 0.283 0.000
I32 Pericarditis in diseases classified elsewhere
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
T33-T35 Frostbite
0.716 0.284 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.716 0.284 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.716 0.284 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.716 0.284 0.000
T00-T07 Injuries involving multiple body regions
0.716 0.284 0.000
M89 Other disorders of bone
0.716 0.284 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.715 0.285 0.000
M33 Dermatopolymyositis
0.715 0.285 0.000
M32 Systemic lupus erythematosus
0.715 0.285 0.000
M30 Polyarteritis nodosa and related conditions
0.715 0.285 0.000
C50-C50 Malignant neoplasm of breast
0.715 0.285 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.714 0.286 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.714 0.286 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.714 0.286 0.000
I27 Other pulmonary heart diseases
0.714 0.286 0.000
I15 Secondary hypertension
0.712 0.288 0.000
G70-G73 Diseases of myoneural junction and muscle
0.712 0.288 0.000
M25.4 Effusion of joint
0.711 0.289 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.710 0.289 0.000
W00-W19 Falls
0.710 0.289 0.000
E10.8 With unspecified complications
0.709 0.291 0.000
E10.7 With multiple complications
0.709 0.291 0.000
E10.6 With other specified complications
0.709 0.291 0.000
E10.2 With renal complications
0.709 0.291 0.000
E10.0 With coma
0.709 0.291 0.000
E27 Other disorders of adrenal gland
0.709 0.291 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.709 0.291 0.000
H66.9 Otitis media, unspecified
0.709 0.291 0.000
T66-T78 Other and unspecified effects of external causes
0.708 0.292 0.000
A30-A49 Other bacterial diseases
0.706 0.294 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.706 0.294 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.705 0.294 0.000
X60-X84 Intentional self-harm
0.705 0.295 0.000
M23.9 Internal derangement of knee, unspecified
0.705 0.295 0.000
M23.5 Chronic instability of knee
0.705 0.295 0.000
M23.1 Discoid meniscus (congenital)
0.705 0.295 0.000
M23.0 Cystic meniscus
0.705 0.295 0.000
E13 Other specified diabetes mellitus
0.704 0.296 0.000
S50-S59 Injuries to the elbow and forearm
0.704 0.296 0.000
I21.9 Acute myocardial infarction, unspecified
0.704 0.296 0.000
E88 Other metabolic disorders
0.703 0.297 0.000
Chapter XXII Codes for special purposes
0.703 0.297 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.702 0.297 0.000
G52 Disorders of other cranial nerves
0.702 0.297 0.000
Y86 Sequelae of other accidents
0.703 0.297 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.701 0.299 0.000
M25.3 Other instability of joint
0.701 0.299 0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters
0.700 0.300 0.000
Q21.1 Atrial septal defect
0.700 0.300 0.000
G59.0 Diabetic mononeuropathy
0.700 0.300 0.000
H70.9 Mastoiditis, unspecified
0.700 0.300 0.000
H73 Other disorders of tympanic membrane
0.699 0.301 0.000
M23.37 Other meniscus derangements-Capsular lig
0.698 0.302 0.000
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)
0.698 0.302 0.000
M23.34 Other meniscus derangements (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.698 0.302 0.000
I36.1 Nonrheumatic tricuspid (valve) insufficiency
0.698 0.302 0.000
M25.9 Joint disorder, unspecified
0.698 0.302 0.000
M24.11 Other articular cartilage disorders (Shoulder region)
0.697 0.303 0.000
H69 Other disorders of Eustachian tube
0.697 0.303 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.697 0.303 0.000
Q35-Q37 Cleft lip and cleft palate
0.697 0.303 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.697 0.303 0.000
M11 Other crystal arthropathies
0.696 0.304 0.000
C77.5 Intrapelvic lymph nodes
0.693 0.307 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.692 0.308 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.691 0.309 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.691 0.309 0.000
D09 Carcinoma in situ of other and unspecified sites
0.691 0.309 0.000
G50.0 Trigeminal neuralgia
0.690 0.310 0.000
S65 Injury of blood vessels at wrist and hand level
0.689 0.311 0.000
M24.9 Joint derangement, unspecified
0.689 0.311 0.000
M24.7 Protrusio acetabuli
0.689 0.311 0.000
M24.6 Ankylosis of joint
0.689 0.311 0.000
M24.5 Contracture of joint
0.689 0.311 0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified
0.689 0.311 0.000
M24.2 Disorder of ligament
0.689 0.311 0.000
M24.0 Loose body in joint
0.689 0.311 0.000
W29 Contact with other powered hand tools and household machinery
0.689 0.311 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.687 0.313 0.000
I49.2 Junctional premature depolarisation
0.686 0.314 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.686 0.314 0.000
M34 Systemic sclerosis
0.685 0.315 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.685 0.315 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.685 0.315 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.685 0.315 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.685 0.315 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.685 0.315 0.000
T36 Poisoning by systemic antibiotics
0.685 0.315 0.000
M25.2 Flail joint
0.685 0.315 0.000
M25.1 Fistula of joint
0.685 0.315 0.000
M25.0 Haemarthrosis
0.685 0.315 0.000
Q00-Q07 Congenital malformations of the nervous system
0.684 0.316 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.683 0.316 0.000
G30-G32 Other degenerative diseases of the nervous system
0.683 0.317 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.682 0.318 0.000
E32 Diseases of thymus
0.682 0.318 0.000
E31 Polyglandular dysfunction
0.682 0.318 0.000
E30 Disorders of puberty, not elsewhere classified
0.682 0.318 0.000
E26 Hyperaldosteronism
0.682 0.318 0.000
E25 Adrenogenital disorders
0.682 0.318 0.000
E24 Cushing's syndrome
0.682 0.318 0.000
E20 Hypoparathyroidism
0.682 0.318 0.000
T51.0 Ethanol
0.681 0.319 0.000
M90 Osteopathies in diseases classified elsewhere
0.681 0.319 0.000
D02 Carcinoma in situ of middle ear and respiratory system
0.680 0.319 0.000
D01 Carcinoma in situ of other and unspecified digestive organs
0.680 0.319 0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.680 0.319 0.000
I30 Acute pericarditis
0.680 0.320 0.000
M13.96 Arthritis, unspecified (Lower leg)
0.680 0.320 0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.679 0.321 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.678 0.322 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.677 0.323 0.000
H68 Eustachian salpingitis and obstruction
0.677 0.323 0.000
H67 Otitis media in diseases classified elsewhere
0.677 0.323 0.000
B99-B99 Other infectious diseases
0.676 0.324 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.676 0.324 0.000
B65-B83 Helminthiases
0.676 0.324 0.000
B50-B64 Protozoal diseases
0.676 0.324 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.676 0.324 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.676 0.324 0.000
A75-A79 Rickettsioses
0.676 0.324 0.000
A70-A74 Other diseases caused by chlamydiae
0.676 0.324 0.000
A65-A69 Other spirochaetal diseases
0.676 0.324 0.000
A20-A28 Certain zoonotic bacterial diseases
0.676 0.324 0.000
A15-A19 Tuberculosis
0.676 0.324 0.000
M07 Psoriatic and enteropathic arthropathies
0.676 0.324 0.000
M86 Osteomyelitis
0.676 0.324 0.000
V40-V49 Car occupant injured in transport accident
0.675 0.325 0.000
S63.4 Traumatic rupture of ligament of finger at metacarpophalangeal and interphalangeal joint(s)
0.674 0.326 0.000
C32.9 Larynx, unspecified
0.673 0.327 0.000
Q27 Other congenital malformations of peripheral vascular system
0.672 0.328 0.000
E28 Ovarian dysfunction
0.672 0.328 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.671 0.329 0.000
S69 Other and unspecified injuries of wrist and hand
0.670 0.330 0.000
Q61.2 Polycystic kidney, adult type
0.669 0.331 0.000
E67 Other hyperalimentation
0.669 0.331 0.000
E68 Sequelae of hyperalimentation
0.669 0.331 0.000
E65 Localised adiposity
0.669 0.331 0.000
O66.5 Failed application of vacuum extractor and forceps, unspecified
0.669 0.331 0.000
C77.1 Intrathoracic lymph nodes
0.669 0.331 0.000
A80-A89 Viral infections of the central nervous system
0.668 0.332 0.000
S01 Open wound of head
0.668 0.332 0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.667 0.333 0.000
I34.8 Other nonrheumatic mitral valve disorders
0.667 0.333 0.000
I34.2 Nonrheumatic mitral (valve) stenosis
0.667 0.333 0.000
X20-X29 Contact with venomous animals and plants
0.667 0.333 0.000
O75.7 Vaginal delivery following previous Caesarean section
0.666 0.334 0.000
B08 Other viral infections characterised by skin and mucous membrane lesions, not elsewhere classified
0.666 0.334 0.000
S63.6 Sprain and strain of finger(s)
0.666 0.334 0.000
G56.9 Mononeuropathy of upper limb, unspecified
0.665 0.334 0.000
G56.4 Causalgia
0.665 0.334 0.000
G56.3 Lesion of radial nerve
0.665 0.334 0.000
G56.1 Other lesions of median nerve
0.665 0.334 0.000
D06.9 Cervix, unspecified
0.665 0.335 0.000
M87 Osteonecrosis
0.665 0.335 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.663 0.337 0.000
S67 Crushing injury of wrist and hand
0.663 0.337 0.000
C79.6 Secondary malignant neoplasm of ovary
0.662 0.338 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.662 0.338 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.662 0.338 0.000
C49 Malignant neoplasm of other connective and soft tissue
0.661 0.339 0.000
E40-E46 Malnutrition
0.661 0.339 0.000
M25.79 Osteophyte (Site unspecified)
0.660 0.340 0.000
M25.73 Osteophyte (Forearm)
0.660 0.340 0.000
M25.72 Osteophyte (Upper arm)
0.660 0.340 0.000
M25.70 Osteophyte (Multiple sites)
0.660 0.340 0.000
H71 Cholesteatoma of middle ear
0.660 0.340 0.000
S61 Open wound of wrist and hand
0.659 0.341 0.000
H65.4 Other chronic nonsuppurative otitis media
0.659 0.341 0.000
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium
0.659 0.341 0.000
C80 Malignant neoplasm without specification of site
0.658 0.342 0.000
I47.9 Paroxysmal tachycardia, unspecified
0.658 0.342 0.000
I47.0 Reentry ventricular arrhythmia
0.658 0.342 0.000
T91 Sequelae of injuries of neck and trunk
0.657 0.343 0.000
C71 Malignant neoplasm of brain
0.657 0.343 0.000
I33.0 Acute and subacute infective endocarditis
0.656 0.344 0.000
M24.19 Other articular cartilage disorders (Site unspecified)
0.656 0.344 0.000
M24.18 Other articular cartilage disorders (Other)
0.656 0.344 0.000
M24.17 Other articular cartilage disorders (Ankle and foot)
0.656 0.344 0.000
M24.15 Other articular cartilage disorders (Pelvic region and thigh)
0.656 0.344 0.000
M24.14 Other articular cartilage disorders (Hand)
0.656 0.344 0.000
M24.12 Other articular cartilage disorders (Upper arm)
0.656 0.344 0.000
M24.10 Other articular cartilage disorders (Multiple sites)
0.656 0.344 0.000
T51.9 Alcohol, unspecified
0.655 0.345 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.654 0.345 0.000
Y35-Y36 Legal intervention and operations of war
0.654 0.345 0.000
Y10-Y34 Event of undetermined intent
0.654 0.345 0.000
Y00-Y09 Assault
0.654 0.345 0.000
X85-X99 Assault
0.654 0.345 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.654 0.345 0.000
X50-X57 Overexertion, travel and privation
0.654 0.345 0.000
X30-X39 Exposure to forces of nature
0.654 0.345 0.000
X10-X19 Contact with heat and hot substances
0.654 0.345 0.000
X00-X09 Exposure to smoke, fire and flames
0.654 0.345 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.654 0.345 0.000
W75-W84 Other accidental threats to breathing
0.654 0.345 0.000
W65-W74 Accidental drowning and submersion
0.654 0.345 0.000
W50-W64 Exposure to animate mechanical forces
0.654 0.345 0.000
V98-V99 Other and unspecified transport accidents
0.654 0.345 0.000
V95-V97 Air and space transport accidents
0.654 0.345 0.000
V90-V94 Water transport accidents
0.654 0.345 0.000
V70-V79 Bus occupant injured in transport accident
0.654 0.345 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.654 0.345 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.654 0.345 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.654 0.345 0.000
V20-V29 Motorcycle rider injured in transport accident
0.654 0.345 0.000
V01-V09 Pedestrian injured in transport accident
0.654 0.345 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.654 0.346 0.000
M14 Arthropathies in other diseases classified elsewhere
0.654 0.346 0.000
M12 Other specific arthropathies
0.654 0.346 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.654 0.346 0.000
M08 Juvenile arthritis
0.654 0.346 0.000
T65 Toxic effect of other and unspecified substances
0.654 0.346 0.000
T62 Toxic effect of other noxious substances eaten as food
0.654 0.346 0.000
T61 Toxic effect of noxious substances eaten as seafood
0.654 0.346 0.000
T60 Toxic effect of pesticides
0.654 0.346 0.000
T59 Toxic effect of other gases, fumes and vapours
0.654 0.346 0.000
T57 Toxic effect of other inorganic substances
0.654 0.346 0.000
T56 Toxic effect of metals
0.654 0.346 0.000
T54 Toxic effect of corrosive substances
0.654 0.346 0.000
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone
0.654 0.346 0.000
T52 Toxic effect of organic solvents
0.654 0.346 0.000
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants
0.654 0.346 0.000
T55 Toxic effect of soaps and detergents
0.654 0.346 0.000
T63 Toxic effect of contact with venomous animals
0.653 0.347 0.000
Q85 Phakomatoses, not elsewhere classified
0.653 0.347 0.000
S12 Fracture of neck
0.652 0.348 0.000
H65.9 Nonsuppurative otitis media, unspecified
0.652 0.348 0.000
V80-V89 Other land transport accidents
0.649 0.350 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.649 0.350 0.000
C34 Malignant neoplasm of bronchus and lung
0.648 0.351 0.000
D05.0 Lobular carcinoma in situ
0.648 0.352 0.000
M13.0 Polyarthritis, unspecified
0.648 0.352 0.000
C61 Malignant neoplasm of prostate
0.648 0.352 0.000
E29.1 Testicular hypofunction
0.648 0.352 0.000
M65 Synovitis and tenosynovitis
0.647 0.353 0.000
G60 Hereditary and idiopathic neuropathy
0.647 0.353 0.000
G64 Other disorders of peripheral nervous system
0.647 0.353 0.000
E15 Nondiabetic hypoglycaemic coma
0.646 0.354 0.000
M23.87 Other internal derangements of knee (Capsular ligament)
0.645 0.355 0.000
M23.86 Other internal derangements of knee (Other and unspecified lateral meniscus)
0.645 0.355 0.000
M23.85 Other internal derangements of knee (Posterior horn of lateral meniscus)
0.645 0.355 0.000
M23.84 Other internal derangements of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.645 0.355 0.000
M23.82 Other internal derangements of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.645 0.355 0.000
M23.80 Other internal derangements of knee (Multiple sites)
0.645 0.355 0.000
T18 Foreign body in alimentary tract
0.644 0.356 0.000
I42 Cardiomyopathy
0.644 0.356 0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.644 0.356 0.000
G23 Other degenerative diseases of basal ganglia
0.643 0.357 0.000
G21 Secondary Parkinsonism
0.643 0.357 0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere
0.643 0.357 0.000
G22 Parkinsonism in diseases classified elsewhere
0.643 0.357 0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]
0.642 0.358 0.000
T40.8 Lysergide [LSD]
0.642 0.358 0.000
T40.7 Cannabis (derivatives)
0.642 0.358 0.000
T40.6 Other and unspecified narcotics
0.642 0.358 0.000
T40.5 Cocaine
0.642 0.358 0.000
T40.3 Methadone
0.642 0.358 0.000
T40.1 Heroin
0.642 0.358 0.000
T40.0 Opium
0.642 0.358 0.000
E10.3 With ophthalmic complications
0.641 0.359 0.000
M25.5 Pain in joint
0.641 0.359 0.000
H74.0 Tympanosclerosis
0.641 0.359 0.000
M25.74 Osteophyte (Hand)
0.640 0.360 0.000
B07 Viral warts
0.640 0.360 0.000
G57.8 Other mononeuropathies of lower limb
0.640 0.360 0.000
H62 Disorders of external ear in diseases classified elsewhere
0.638 0.362 0.000
C25.0 Head of pancreas
0.638 0.362 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.637 0.362 0.000
E14.3 With ophthalmic complications
0.637 0.363 0.000
C77.0 Lymph nodes of head, face and neck
0.636 0.364 0.000
Q66 Congenital deformities of feet
0.635 0.364 0.000
I13 Hypertensive heart and renal disease
0.635 0.364 0.000
I11 Hypertensive heart disease
0.635 0.364 0.000
E66.2 Extreme obesity with alveolar hypoventilation
0.635 0.365 0.000
E66.1 Drug-induced obesity
0.635 0.365 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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