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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs114437140
log Bayes Factor = 13.3145
Chromosome 1   position 68,682,970  (GRCh37) Explore rs114437140 on Ensembl!
Variant rs114437140 is part of Cluster X0072

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
Chapter XX External causes of morbidity and mortality
0.999 0.001 0.000
E70-E90 Metabolic disorders
0.999 0.001 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.995 0.005 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.992 0.008 0.000
S40-S49 Injuries to the shoulder and upper arm
0.989 0.011 0.000
E83 Disorders of mineral metabolism
0.984 0.016 0.000
S00-S09 Injuries to the head
0.982 0.018 0.000
E83.5 Disorders of calcium metabolism
0.977 0.023 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.975 0.025 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.975 0.025 0.000
S80-S89 Injuries to the knee and lower leg
0.973 0.027 0.000
S42 Fracture of shoulder and upper arm
0.966 0.034 0.000
C50-C50 Malignant neoplasm of breast
0.965 0.035 0.000
S80 Superficial injury of lower leg
0.963 0.037 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.962 0.038 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.958 0.042 0.000
S01 Open wound of head
0.958 0.042 0.000
S20-S29 Injuries to the thorax
0.957 0.043 0.000
S80.9 Superficial injury of lower leg, unspecified
0.954 0.046 0.000
Chapter IX Diseases of the circulatory system
0.947 0.053 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.942 0.058 0.000
C50 Malignant neoplasm of breast
0.940 0.060 0.000
E10-E14 Diabetes mellitus
0.940 0.060 0.000
I30-I52 Other forms of heart disease
0.935 0.065 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.931 0.069 0.000
S42.2 Fracture of upper end of humerus
0.926 0.074 0.000
E20-E35 Disorders of other endocrine glands
0.924 0.076 0.000
Chapter I Certain infectious and parasitic diseases
0.921 0.079 0.000
Y43 Primarily systemic agents
0.912 0.088 0.000
Chapter XIV Diseases of the genitourinary system
0.909 0.091 0.000
Chapter VII Diseases of the eye and adnexa
0.909 0.091 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.907 0.093 0.000
N17-N19 Renal failure
0.907 0.093 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.907 0.093 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.906 0.094 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.901 0.099 0.000
S42.20 Fracture of upper end of humerus (closed)
0.898 0.102 0.000
E87.5 Hyperkalaemia
0.895 0.105 0.000
C50.4 Upper-outer quadrant of breast
0.894 0.106 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.892 0.108 0.000
I44 Atrioventricular and left bundle-branch block
0.888 0.112 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.882 0.118 0.000
E86 Volume depletion
0.879 0.121 0.000
C83.3 Large cell (diffuse)
0.877 0.123 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.874 0.126 0.000
N18 Chronic renal failure
0.869 0.131 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.867 0.133 0.000
T66-T78 Other and unspecified effects of external causes
0.866 0.134 0.000
S22.4 Multiple fractures of ribs
0.863 0.137 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.862 0.138 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.862 0.138 0.000
N19 Unspecified renal failure
0.861 0.139 0.000
E11 Non-insulin-dependent diabetes mellitus
0.858 0.142 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.854 0.146 0.000
Y43.3 Other antineoplastic drugs
0.854 0.146 0.000
S01.8 Open wound of other parts of head
0.854 0.146 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.853 0.147 0.000
C91 Lymphoid leukaemia
0.851 0.149 0.000
H30-H36 Disorders of choroid and retina
0.850 0.150 0.000
D46 Myelodysplastic syndromes
0.848 0.152 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.846 0.154 0.000
S00 Superficial injury of head
0.844 0.156 0.000
S01.4 Open wound of cheek and temporomandibular area
0.843 0.157 0.000
E88 Other metabolic disorders
0.836 0.164 0.000
N00-N08 Glomerular diseases
0.836 0.164 0.000
C64-C68 Malignant neoplasms of urinary tract
0.833 0.167 0.000
S22.40 Multiple fractures of ribs (closed)
0.832 0.168 0.000
D00-D09 In situ neoplasms
0.825 0.175 0.000
A30-A49 Other bacterial diseases
0.824 0.176 0.000
W20-W49 Exposure to inanimate mechanical forces
0.824 0.176 0.000
T82.1 Mechanical complication of cardiac electronic device
0.824 0.176 0.000
C50.8 Overlapping lesion of breast
0.824 0.176 0.000
E87.7 Fluid overload
0.823 0.177 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.822 0.178 0.000
N17 Acute renal failure
0.819 0.181 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.819 0.181 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.815 0.185 0.000
I51 Complications and ill-defined descriptions of heart disease
0.814 0.186 0.000
I50 Heart failure
0.814 0.186 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.814 0.186 0.000
I49 Other cardiac arrhythmias
0.811 0.189 0.000
Chapter VIII Diseases of the ear and mastoid process
0.811 0.189 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.809 0.191 0.000
E10 Insulin-dependent diabetes mellitus
0.808 0.192 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.806 0.194 0.000
S01.0 Open wound of scalp
0.804 0.196 0.000
T86 Failure and rejection of transplanted organs and tissues
0.804 0.196 0.000
S50-S59 Injuries to the elbow and forearm
0.804 0.196 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.804 0.196 0.000
T51 Toxic effect of alcohol
0.798 0.202 0.000
C77.3 Axillary and upper limb lymph nodes
0.791 0.209 0.000
Y52 Agents primarily affecting the cardiovascular system
0.790 0.210 0.000
I31 Other diseases of pericardium
0.790 0.210 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.789 0.211 0.000
I05-I09 Chronic rheumatic heart diseases
0.788 0.212 0.000
N18.0 End-stage renal disease
0.788 0.212 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.787 0.213 0.000
W50-W64 Exposure to animate mechanical forces
0.786 0.214 0.000
I51.8 Other ill-defined heart diseases
0.786 0.214 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.786 0.214 0.000
A00-A09 Intestinal infectious diseases
0.785 0.215 0.000
C83.0 Small cell (diffuse)
0.783 0.217 0.000
S70-S79 Injuries to the hip and thigh
0.783 0.217 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.782 0.218 0.000
Y57 Other and unspecified drugs and medicaments
0.779 0.221 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.778 0.222 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.777 0.223 0.000
S42.0 Fracture of clavicle
0.776 0.224 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.775 0.224 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.775 0.225 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.774 0.226 0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified
0.774 0.226 0.000
C79 Secondary malignant neoplasm of other sites
0.773 0.227 0.000
S42.9 Fracture of shoulder girdle, part unspecified
0.773 0.227 0.000
I44.3 Other and unspecified atrioventricular block
0.773 0.227 0.000
S27 Injury of other and unspecified intrathoracic organs
0.773 0.227 0.000
S80.0 Contusion of knee
0.769 0.231 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.769 0.231 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.769 0.231 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.768 0.232 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.768 0.232 0.000
C77.9 Lymph node, unspecified
0.768 0.232 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.766 0.234 0.000
N18.5 Chronic kidney disease, stage 5
0.765 0.235 0.000
E83.1 Disorders of iron metabolism
0.764 0.236 0.000
S02 Fracture of skull and facial bones
0.764 0.236 0.000
V20-V29 Motorcycle rider injured in transport accident
0.763 0.237 0.000
X20-X29 Contact with venomous animals and plants
0.761 0.239 0.000
Y40 Systemic antibiotics
0.759 0.240 0.000
S60-S69 Injuries to the wrist and hand
0.758 0.242 0.000
I44.1 Atrioventricular block, second degree
0.758 0.242 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.757 0.242 0.000
D46.9 Myelodysplastic syndrome, unspecified
0.757 0.243 0.000
H80-H83 Diseases of inner ear
0.757 0.243 0.000
S05 Injury of eye and orbit
0.756 0.244 0.000
N17.9 Acute renal failure, unspecified
0.756 0.244 0.000
S43.0 Dislocation of shoulder joint
0.755 0.245 0.000
S40 Superficial injury of shoulder and upper arm
0.755 0.245 0.000
E40-E46 Malnutrition
0.754 0.246 0.000
E87.6 Hypokalaemia
0.754 0.246 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.754 0.246 0.000
V10-V19 Pedal cyclist injured in transport accident
0.753 0.247 0.000
I50.9 Heart failure, unspecified
0.753 0.247 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.751 0.249 0.000
E11.2 With renal complications
0.750 0.250 0.000
E20 Hypoparathyroidism
0.750 0.250 0.000
C91.1 Chronic lymphocytic leukaemia
0.748 0.252 0.000
Y45.0 Opioids and related analgesics
0.746 0.254 0.000
N18.9 Chronic renal failure, unspecified
0.746 0.254 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.745 0.255 0.000
S01.5 Open wound of lip and oral cavity
0.744 0.256 0.000
E65-E68 Obesity and other hyperalimentation
0.742 0.258 0.000
H34 Retinal vascular occlusions
0.741 0.259 0.000
E34 Other endocrine disorders
0.740 0.260 0.000
S89 Other and unspecified injuries of lower leg
0.739 0.261 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.739 0.261 0.000
C85.7 Other specified types of non-Hodgkin's lymphoma
0.739 0.261 0.000
W00-W19 Falls
0.738 0.262 0.000
T51.0 Ethanol
0.738 0.262 0.000
Q50-Q56 Congenital malformations of genital organs
0.737 0.262 0.000
S00.9 Superficial injury of head, part unspecified
0.737 0.263 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.734 0.265 0.000
X60-X84 Intentional self-harm
0.733 0.267 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.733 0.267 0.000
E10.3 With ophthalmic complications
0.733 0.267 0.000
S32 Fracture of lumbar spine and pelvis
0.732 0.268 0.000
D48.1 Connective and other soft tissue
0.731 0.269 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.731 0.269 0.000
C92 Myeloid leukaemia
0.730 0.270 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.728 0.272 0.000
C50.2 Upper-inner quadrant of breast
0.727 0.272 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.727 0.272 0.000
H36 Retinal disorders in diseases classified elsewhere
0.727 0.272 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.726 0.274 0.000
C81 Hodgkin's disease
0.725 0.275 0.000
H55-H59 Other disorders of eye and adnexa
0.724 0.276 0.000
S42.4 Fracture of lower end of humerus
0.724 0.276 0.000
T78 Adverse effects, not elsewhere classified
0.722 0.278 0.000
H83 Other diseases of inner ear
0.722 0.278 0.000
Chapter XXII Codes for special purposes
0.721 0.279 0.000
C77.2 Intra-abdominal lymph nodes
0.721 0.279 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.720 0.280 0.000
Y42.5 Other oestrogens and progestogens
0.720 0.280 0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.719 0.281 0.000
S90-S99 Injuries to the ankle and foot
0.719 0.281 0.000
Q60-Q64 Congenital malformations of the urinary system
0.718 0.282 0.000
C50.5 Lower-outer quadrant of breast
0.718 0.282 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.717 0.282 0.000
L89 Decubitus ulcer
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S10-S19 Injuries to the neck
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.717 0.283 0.000
Y35-Y36 Legal intervention and operations of war
0.716 0.284 0.000
Y10-Y34 Event of undetermined intent
0.716 0.284 0.000
Y00-Y09 Assault
0.716 0.284 0.000
X85-X99 Assault
0.716 0.284 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.716 0.284 0.000
X50-X57 Overexertion, travel and privation
0.716 0.284 0.000
X30-X39 Exposure to forces of nature
0.716 0.284 0.000
X10-X19 Contact with heat and hot substances
0.716 0.284 0.000
X00-X09 Exposure to smoke, fire and flames
0.716 0.284 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.716 0.284 0.000
W75-W84 Other accidental threats to breathing
0.716 0.284 0.000
W65-W74 Accidental drowning and submersion
0.716 0.284 0.000
V98-V99 Other and unspecified transport accidents
0.716 0.284 0.000
V95-V97 Air and space transport accidents
0.716 0.284 0.000
V90-V94 Water transport accidents
0.716 0.284 0.000
V80-V89 Other land transport accidents
0.716 0.284 0.000
V70-V79 Bus occupant injured in transport accident
0.716 0.284 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.716 0.284 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.716 0.284 0.000
V40-V49 Car occupant injured in transport accident
0.716 0.284 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.716 0.284 0.000
V01-V09 Pedestrian injured in transport accident
0.716 0.284 0.000
E85 Amyloidosis
0.716 0.284 0.000
E84 Cystic fibrosis
0.716 0.284 0.000
E79 Disorders of purine and pyrimidine metabolism
0.716 0.284 0.000
E77 Disorders of glycoprotein metabolism
0.716 0.284 0.000
E76 Disorders of glycosaminoglycan metabolism
0.716 0.284 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.716 0.284 0.000
E74 Other disorders of carbohydrate metabolism
0.716 0.284 0.000
E73 Lactose intolerance
0.716 0.284 0.000
E72 Other disorders of amino-acid metabolism
0.716 0.284 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.716 0.284 0.000
E70 Disorders of aromatic amino-acid metabolism
0.716 0.284 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.716 0.284 0.000
Y42.7 Androgens and anabolic congeners
0.716 0.284 0.000
N08.3 Glomerular disorders in diabetes mellitus
0.715 0.285 0.000
H35 Other retinal disorders
0.715 0.285 0.000
T79-T79 Certain early complications of trauma
0.714 0.285 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.713 0.286 0.000
C95 Leukaemia of unspecified cell type
0.713 0.286 0.000
C94 Other leukaemias of specified cell type
0.713 0.286 0.000
C93 Monocytic leukaemia
0.713 0.286 0.000
C88 Malignant immunoproliferative diseases
0.713 0.286 0.000
C86 Other specified types of T/NK-cell lymphoma
0.713 0.286 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.713 0.286 0.000
S20 Superficial injury of thorax
0.713 0.287 0.000
B25-B34 Other viral diseases
0.712 0.288 0.000
Y59 Other and unspecified vaccines and biological substances
0.711 0.289 0.000
Y58 Bacterial vaccines
0.711 0.289 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.711 0.289 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.711 0.289 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.711 0.289 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.711 0.289 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.711 0.289 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.711 0.289 0.000
Y48 Anaesthetics and therapeutic gases
0.711 0.289 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.711 0.289 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.711 0.289 0.000
Y44 Agents primarily affecting blood constituents
0.711 0.289 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.711 0.289 0.000
I44.0 Atrioventricular block, first degree
0.711 0.289 0.000
S06 Intracranial injury
0.711 0.289 0.000
E87.0 Hyperosmolality and hypernatraemia
0.710 0.290 0.000
E28 Ovarian dysfunction
0.710 0.290 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.709 0.291 0.000
S48 Traumatic amputation of shoulder and upper arm
0.709 0.291 0.000
S45 Injury of blood vessels at shoulder and upper arm level
0.709 0.291 0.000
S44 Injury of nerves at shoulder and upper arm level
0.709 0.291 0.000
S41 Open wound of shoulder and upper arm
0.709 0.291 0.000
S47 Crushing injury of shoulder and upper arm
0.709 0.291 0.000
C50.1 Central portion of breast
0.709 0.291 0.000
S22.0 Fracture of thoracic vertebra
0.708 0.292 0.000
S01.2 Open wound of nose
0.708 0.292 0.000
E50-E64 Other nutritional deficiencies
0.707 0.293 0.000
S22.2 Fracture of sternum
0.706 0.294 0.000
S42.3 Fracture of shaft of humerus
0.706 0.294 0.000
E83.9 Disorder of mineral metabolism, unspecified
0.705 0.295 0.000
E83.8 Other disorders of mineral metabolism
0.705 0.295 0.000
E83.2 Disorders of zinc metabolism
0.705 0.295 0.000
E83.0 Disorders of copper metabolism
0.705 0.295 0.000
S01.9 Open wound of head, part unspecified
0.704 0.295 0.000
E11.4 With neurological complications
0.704 0.296 0.000
S08 Traumatic amputation of part of head
0.704 0.296 0.000
S07 Crushing injury of head
0.704 0.296 0.000
S04 Injury of cranial nerves
0.704 0.296 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.704 0.296 0.000
B95-B98 Bacterial, viral and other infectious agents
0.703 0.297 0.000
S01.3 Open wound of ear
0.702 0.297 0.000
Q00-Q07 Congenital malformations of the nervous system
0.702 0.298 0.000
T68 Hypothermia
0.701 0.299 0.000
Q80-Q89 Other congenital malformations
0.701 0.299 0.000
E87.2 Acidosis
0.701 0.299 0.000
C85.1 B-cell lymphoma, unspecified
0.701 0.299 0.000
D43.2 Brain, unspecified
0.700 0.300 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.699 0.301 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.699 0.301 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.699 0.301 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.699 0.301 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.699 0.301 0.000
T87 Complications peculiar to reattachment and amputation
0.699 0.301 0.000
S88 Traumatic amputation of lower leg
0.697 0.303 0.000
S87 Crushing injury of lower leg
0.697 0.303 0.000
S86 Injury of muscle and tendon at lower leg level
0.697 0.303 0.000
S85 Injury of blood vessels at lower leg level
0.697 0.303 0.000
S84 Injury of nerves at lower leg level
0.697 0.303 0.000
C43 Malignant melanoma of skin
0.697 0.303 0.000
H83.0 Labyrinthitis
0.697 0.303 0.000
S42.1 Fracture of scapula
0.697 0.303 0.000
I44.2 Atrioventricular block, complete
0.697 0.303 0.000
D03 Melanoma in situ
0.697 0.303 0.000
E80.4 Gilbert's syndrome
0.695 0.305 0.000
L91 Hypertrophic disorders of skin
0.694 0.305 0.000
S42.8 Fracture of other parts of shoulder and upper arm
0.693 0.307 0.000
S42.7 Multiple fractures of clavicle, scapula and humerus
0.693 0.307 0.000
Y85 Sequelae of transport accidents
0.693 0.307 0.000
S80.8 Other superficial injuries of lower leg
0.691 0.309 0.000
S80.7 Multiple superficial injuries of lower leg
0.691 0.309 0.000
S80.1 Contusion of other and unspecified parts of lower leg
0.691 0.309 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.690 0.309 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.690 0.310 0.000
E87.4 Mixed disorder of acid-base balance
0.690 0.310 0.000
E87.3 Alkalosis
0.690 0.310 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.689 0.311 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.689 0.311 0.000
E29 Testicular dysfunction
0.689 0.311 0.000
W25 Contact with sharp glass
0.688 0.312 0.000
I49.0 Ventricular fibrillation and flutter
0.688 0.312 0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft
0.687 0.313 0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis
0.687 0.313 0.000
T82.4 Mechanical complication of vascular dialysis catheter
0.687 0.313 0.000
T82.3 Mechanical complication of other vascular grafts
0.687 0.313 0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.687 0.313 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.687 0.313 0.000
S01.7 Multiple open wounds of head
0.687 0.313 0.000
A49 Bacterial infection of unspecified site
0.687 0.313 0.000
L60-L75 Disorders of skin appendages
0.687 0.313 0.000
I26 Pulmonary embolism
0.687 0.313 0.000
S29 Other and unspecified injuries of thorax
0.686 0.314 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.686 0.314 0.000
S26 Injury of heart
0.686 0.314 0.000
S25 Injury of blood vessels of thorax
0.686 0.314 0.000
S24 Injury of nerves and spinal cord at thorax level
0.686 0.314 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.686 0.314 0.000
S21 Open wound of thorax
0.686 0.314 0.000
I30 Acute pericarditis
0.685 0.315 0.000
E11.3 With ophthalmic complications
0.685 0.315 0.000
D45 Polycythaemia vera
0.684 0.316 0.000
I42 Cardiomyopathy
0.684 0.316 0.000
C90.0 Multiple myeloma
0.684 0.316 0.000
I38 Endocarditis, valve unspecified
0.683 0.317 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.683 0.317 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.682 0.318 0.000
T86.0 Bone-marrow transplant rejection
0.681 0.319 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.681 0.319 0.000
E11.6 With other specified complications
0.681 0.319 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.679 0.321 0.000
I00-I02 Acute rheumatic fever
0.679 0.321 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.677 0.323 0.000
D48.5 Skin
0.676 0.324 0.000
N60-N64 Disorders of breast
0.676 0.324 0.000
S01.1 Open wound of eyelid and periocular area
0.676 0.324 0.000
I44.6 Other and unspecified fascicular block
0.676 0.324 0.000
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified
0.675 0.325 0.000
C83.8 Other types of diffuse non-Hodgkin's lymphoma
0.675 0.325 0.000
C83.7 Burkitt's tumour
0.675 0.325 0.000
C83.6 Undifferentiated (diffuse)
0.675 0.325 0.000
C83.5 Lymphoblastic (diffuse)
0.675 0.325 0.000
C83.4 Immunoblastic (diffuse)
0.675 0.325 0.000
C83.2 Mixed small and large cell (diffuse)
0.675 0.325 0.000
C83.1 Small cleaved cell (diffuse)
0.675 0.325 0.000
N02 Recurrent and persistent haematuria
0.674 0.326 0.000
E23 Hypofunction and other disorders of pituitary gland
0.674 0.326 0.000
C50.6 Axillary tail of breast
0.674 0.326 0.000
C50.0 Nipple and areola
0.674 0.326 0.000
E12 Malnutrition-related diabetes mellitus
0.674 0.326 0.000
C77.8 Lymph nodes of multiple regions
0.674 0.326 0.000
C77.1 Intrathoracic lymph nodes
0.673 0.327 0.000
E13 Other specified diabetes mellitus
0.673 0.327 0.000
N99-N99 Other disorders of the genitourinary system
0.673 0.327 0.000
Y79 Orthopaedic devices associated with adverse incidents
0.673 0.327 0.000
E22 Hyperfunction of pituitary gland
0.672 0.328 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.672 0.328 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.671 0.329 0.000
E10.2 With renal complications
0.671 0.329 0.000
I52 Other heart disorders in diseases classified elsewhere
0.671 0.329 0.000
I48 Atrial fibrillation and flutter
0.671 0.329 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.671 0.329 0.000
I41 Myocarditis in diseases classified elsewhere
0.671 0.329 0.000
I40 Acute myocarditis
0.671 0.329 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.671 0.329 0.000
I37 Pulmonary valve disorders
0.671 0.329 0.000
I36 Nonrheumatic tricuspid valve disorders
0.671 0.329 0.000
I32 Pericarditis in diseases classified elsewhere
0.671 0.329 0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.670 0.330 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.670 0.330 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.669 0.331 0.000
I05 Rheumatic mitral valve diseases
0.669 0.331 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.668 0.332 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.668 0.332 0.000
H10-H13 Disorders of conjunctiva
0.668 0.332 0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.668 0.332 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.667 0.333 0.000
S42.21 Fracture of upper end of humerus (open)
0.664 0.336 0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care
0.664 0.336 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.662 0.338 0.000
E32 Diseases of thymus
0.662 0.338 0.000
E31 Polyglandular dysfunction
0.662 0.338 0.000
E30 Disorders of puberty, not elsewhere classified
0.662 0.338 0.000
E26 Hyperaldosteronism
0.662 0.338 0.000
E25 Adrenogenital disorders
0.662 0.338 0.000
E24 Cushing's syndrome
0.662 0.338 0.000
T88.7 Unspecified adverse effect of drug or medicament
0.662 0.338 0.000
W21 Striking against or struck by sports equipment
0.662 0.338 0.000
D48.0 Bone and articular cartilage
0.661 0.339 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.661 0.339 0.000
E14 Unspecified diabetes mellitus
0.661 0.339 0.000
B99-B99 Other infectious diseases
0.660 0.340 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.660 0.340 0.000
B65-B83 Helminthiases
0.660 0.340 0.000
B50-B64 Protozoal diseases
0.660 0.340 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.660 0.340 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.660 0.340 0.000
A75-A79 Rickettsioses
0.660 0.340 0.000
A70-A74 Other diseases caused by chlamydiae
0.660 0.340 0.000
A65-A69 Other spirochaetal diseases
0.660 0.340 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.660 0.340 0.000
A20-A28 Certain zoonotic bacterial diseases
0.660 0.340 0.000
A15-A19 Tuberculosis
0.660 0.340 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.659 0.341 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.658 0.342 0.000
I27 Other pulmonary heart diseases
0.658 0.342 0.000
I33 Acute and subacute endocarditis
0.655 0.344 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.655 0.345 0.000
Y43.9 Primarily systemic agent, unspecified
0.654 0.346 0.000
Y43.8 Other primarily systemic agents, not elsewhere classified
0.654 0.346 0.000
Y43.6 Enzymes, not elsewhere classified
0.654 0.346 0.000
Y43.5 Acidifying and alkalising agents
0.654 0.346 0.000
Y43.4 Immunosuppressive agents
0.654 0.346 0.000
Y43.2 Antineoplastic natural products
0.654 0.346 0.000
Y43.1 Antineoplastic antimetabolites
0.654 0.346 0.000
Y43.0 Antiallergic and antiemetic drugs
0.654 0.346 0.000
I45 Other conduction disorders
0.651 0.349 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.650 0.349 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.650 0.349 0.000
Q35-Q37 Cleft lip and cleft palate
0.650 0.349 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.650 0.349 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.650 0.349 0.000
A40 Streptococcal septicaemia
0.650 0.350 0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.650 0.350 0.000
C85.0 Lymphosarcoma
0.650 0.350 0.000
S22.9 Fracture of bony thorax, part unspecified
0.650 0.350 0.000
S22.8 Fracture of other parts of bony thorax
0.650 0.350 0.000
S22.5 Flail chest
0.650 0.350 0.000
S22.1 Multiple fractures of thoracic spine
0.650 0.350 0.000
E89.2 Postprocedural hypoparathyroidism
0.649 0.351 0.000
I47 Paroxysmal tachycardia
0.648 0.352 0.000
I49.5 Sick sinus syndrome
0.648 0.352 0.000
I31.9 Disease of pericardium, unspecified
0.647 0.353 0.000
A80-A89 Viral infections of the central nervous system
0.646 0.354 0.000
L90 Atrophic disorders of skin
0.646 0.354 0.000
Y42.9 Other and unspecified hormone antagonists
0.646 0.354 0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes
0.646 0.354 0.000
Y42.4 Oral contraceptives
0.646 0.354 0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.646 0.354 0.000
Y42.2 Antithyroid drugs
0.646 0.354 0.000
Y42.1 Thyroid hormones and substitutes
0.646 0.354 0.000
Y42.0 Glucocorticoids and synthetic analogs
0.646 0.354 0.000
C66 Malignant neoplasm of ureter
0.646 0.354 0.000
D47.3 Essential (haemorrhagic) thrombocythaemia
0.646 0.354 0.000
S81 Open wound of lower leg
0.645 0.354 0.000
H53-H54 Visual disturbances and blindness
0.643 0.357 0.000
I95 Hypotension
0.643 0.357 0.000
N18.4 Chronic kidney disease, stage 4
0.641 0.359 0.000
A46 Erysipelas
0.641 0.359 0.000
C77.4 Inguinal and lower limb lymph nodes
0.641 0.359 0.000
I34 Nonrheumatic mitral valve disorders
0.640 0.360 0.000
H36.0 Diabetic retinopathy
0.640 0.360 0.000
E83.3 Disorders of phosphorus metabolism
0.639 0.360 0.000
S42.00 Fracture of clavicle (closed)
0.639 0.361 0.000
Y85.0 Sequelae of motor-vehicle accident
0.639 0.361 0.000
L40-L45 Papulosquamous disorders
0.637 0.363 0.000
I44.5 Left posterior fascicular block
0.636 0.363 0.000
I44.4 Left anterior fascicular block
0.636 0.363 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.636 0.364 0.000
S42.90 Fracture of shoulder girdle, part unspecified (closed)
0.635 0.365 0.000
Y95 Nosocomial condition
0.635 0.365 0.000
C77.0 Lymph nodes of head, face and neck
0.635 0.365 0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.635 0.365 0.000
W50 Hit, struck, kicked, twisted, bitten or scratched by another person
0.634 0.366 0.000
T65 Toxic effect of other and unspecified substances
0.633 0.367 0.000
T63 Toxic effect of contact with venomous animals
0.633 0.367 0.000
T62 Toxic effect of other noxious substances eaten as food
0.633 0.367 0.000
T61 Toxic effect of noxious substances eaten as seafood
0.633 0.367 0.000
T60 Toxic effect of pesticides
0.633 0.367 0.000
T59 Toxic effect of other gases, fumes and vapours
0.633 0.367 0.000
T57 Toxic effect of other inorganic substances
0.633 0.367 0.000
T56 Toxic effect of metals
0.633 0.367 0.000
T54 Toxic effect of corrosive substances
0.633 0.367 0.000
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone
0.633 0.367 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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