TreeWAS – Variant ID: rs114469043

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
# Top node	1.000	0.000	0.000
K20-K31 Diseases of oesophagus, stomach and duodenum	1.000	0.000	0.000
Chapter XI Diseases of the digestive system	1.000	0.000	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	1.000	0.000	0.000
Chapter XIV Diseases of the genitourinary system	0.999	0.001	0.000
K20 Oesophagitis	0.998	0.002	0.000
N17-N19 Renal failure	0.998	0.002	0.000
Chapter II Neoplasms	0.995	0.005	0.000
N20-N23 Urolithiasis	0.994	0.006	0.000
Chapter XII Diseases of the skin and subcutaneous tissue	0.990	0.010	0.000
N20 Calculus of kidney and ureter	0.988	0.012	0.000
S60-S69 Injuries to the wrist and hand	0.985	0.015	0.000
Chapter XX External causes of morbidity and mortality	0.983	0.017	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.982	0.018	0.000
K26 Duodenal ulcer	0.981	0.019	0.000
N18 Chronic renal failure	0.978	0.022	0.000
Chapter VII Diseases of the eye and adnexa	0.976	0.024	0.000
N20.0 Calculus of kidney	0.973	0.027	0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.973	0.027	0.000
L80-L99 Other disorders of the skin and subcutaneous tissue	0.967	0.033	0.000
S61 Open wound of wrist and hand	0.966	0.034	0.000
N19 Unspecified renal failure	0.965	0.035	0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws	0.961	0.039	0.000
K26.9 Unspecified as acute or chronic, without haemorrhage or perforation	0.960	0.040	0.000
E70-E90 Metabolic disorders	0.955	0.045	0.000
S61.0 Open wound of finger(s) without damage to nail	0.951	0.049	0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.949	0.051	0.000
K22 Other diseases of oesophagus	0.945	0.055	0.000
Chapter VI Diseases of the nervous system	0.942	0.058	0.000
Chapter XXI Factors influencing health status and contact with health services	0.942	0.058	0.000
D37-D48 Neoplasms of uncertain or unknown behaviour	0.938	0.062	0.000
K29 Gastritis and duodenitis	0.935	0.065	0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.933	0.067	0.000
L00-L08 Infections of the skin and subcutaneous tissue	0.933	0.067	0.000
L82 Seborrhoeic keratosis	0.931	0.069	0.000
G50-G59 Nerve, nerve root and plexus disorders	0.928	0.072	0.000
C64-C68 Malignant neoplasms of urinary tract	0.927	0.073	0.000
G56 Mononeuropathies of upper limb	0.922	0.078	0.000
N18.9 Chronic renal failure, unspecified	0.921	0.079	0.000
K22.1 Ulcer of oesophagus	0.918	0.082	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.917	0.083	0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.917	0.083	0.000
G56.0 Carpal tunnel syndrome	0.913	0.087	0.000
Chapter V Mental and behavioural disorders	0.910	0.090	0.000
Z95 Presence of cardiac and vascular implants and grafts	0.907	0.093	0.000
E20-E35 Disorders of other endocrine glands	0.906	0.094	0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status	0.906	0.094	0.000
Chapter IX Diseases of the circulatory system	0.902	0.098	0.000
K29.8 Duodenitis	0.902	0.098	0.000
H25-H28 Disorders of lens	0.901	0.099	0.000
N20.1 Calculus of ureter	0.884	0.116	0.000
I30-I52 Other forms of heart disease	0.884	0.116	0.000
H26 Other cataract	0.883	0.117	0.000
H53-H54 Visual disturbances and blindness	0.882	0.118	0.000
N17 Acute renal failure	0.881	0.119	0.000
C67 Malignant neoplasm of bladder	0.878	0.122	0.000
N00-N08 Glomerular diseases	0.874	0.126	0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.873	0.127	0.000
E86 Volume depletion	0.872	0.128	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.870	0.130	0.000
K29.6 Other gastritis	0.868	0.132	0.000
N23 Unspecified renal colic	0.865	0.135	0.000
Z95.5 Presence of coronary angioplasty implant and graft	0.862	0.138	0.000
E87 Other disorders of fluid, electrolyte and acid-base balance	0.862	0.138	0.000
H26.9 Cataract, unspecified	0.862	0.138	0.000
E00-E07 Disorders of thyroid gland	0.860	0.140	0.000
L92 Granulomatous disorders of skin and subcutaneous tissue	0.857	0.143	0.000
T85 Complications of other internal prosthetic devices, implants and grafts	0.848	0.152	0.000
Z95.1 Presence of aortocoronary bypass graft	0.847	0.153	0.000
L03 Cellulitis	0.846	0.154	0.000
K22.2 Oesophageal obstruction	0.846	0.154	0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type	0.845	0.155	0.000
K07 Dentofacial anomalies [including malocclusion]	0.843	0.157	0.000
S20-S29 Injuries to the thorax	0.843	0.157	0.000
Z92 Personal history of medical treatment	0.841	0.159	0.000
T84.1 Mechanical complication of internal fixation device of bones of limb	0.840	0.160	0.000
Z95.2 Presence of prosthetic heart valve	0.838	0.162	0.000
I47 Paroxysmal tachycardia	0.837	0.163	0.000
K06 Other disorders of gingiva and edentulous alveolar ridge	0.836	0.164	0.000
H40-H42 Glaucoma	0.835	0.165	0.000
C67.9 Bladder, unspecified	0.835	0.165	0.000
C85.1 B-cell lymphoma, unspecified	0.831	0.169	0.000
Z93 Artificial opening status	0.831	0.169	0.000
C43-C44 Melanoma and other malignant neoplasms of skin	0.830	0.170	0.000
I35 Nonrheumatic aortic valve disorders	0.829	0.171	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.826	0.174	0.000
N18.3 Chronic kidney disease, stage 3	0.824	0.176	0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.823	0.177	0.000
I44 Atrioventricular and left bundle-branch block	0.822	0.178	0.000
E03 Other hypothyroidism	0.818	0.182	0.000
N18.2 Chronic kidney disease, stage 2	0.817	0.183	0.000
Z95.8 Presence of other cardiac and vascular implants and grafts	0.817	0.183	0.000
D00-D09 In situ neoplasms	0.813	0.187	0.000
F30-F39 Mood [affective] disorders	0.812	0.187	0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.812	0.188	0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.811	0.189	0.000
G56.2 Lesion of ulnar nerve	0.811	0.189	0.000
T66-T78 Other and unspecified effects of external causes	0.810	0.190	0.000
Z94 Transplanted organ and tissue status	0.808	0.192	0.000
J45.9 Asthma, unspecified	0.000	0.192	0.808
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.807	0.193	0.000
Z00-Z13 Persons encountering health services for examination and investigation	0.807	0.193	0.000
H53 Visual disturbances	0.805	0.195	0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.803	0.197	0.000
N03 Chronic nephritic syndrome	0.798	0.202	0.000
Y57 Other and unspecified drugs and medicaments	0.798	0.202	0.000
W20-W49 Exposure to inanimate mechanical forces	0.797	0.203	0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.795	0.205	0.000
F40-F48 Neurotic, stress-related and somatoform disorders	0.794	0.206	0.000
L85 Other epidermal thickening	0.793	0.207	0.000
K05 Gingivitis and periodontal diseases	0.791	0.209	0.000
S61.8 Open wound of other parts of wrist and hand	0.791	0.209	0.000
S70-S79 Injuries to the hip and thigh	0.790	0.210	0.000
C15-C26 Malignant neoplasms of digestive organs	0.789	0.211	0.000
S66 Injury of muscle and tendon at wrist and hand level	0.789	0.211	0.000
E03.9 Hypothyroidism, unspecified	0.788	0.212	0.000
Z92.4 Personal history of major surgery, not elsewhere classified	0.788	0.212	0.000
E87.1 Hypo-osmolality and hyponatraemia	0.788	0.212	0.000
K14 Diseases of tongue	0.788	0.212	0.000
K25 Gastric ulcer	0.787	0.213	0.000
I44.0 Atrioventricular block, first degree	0.785	0.215	0.000
K04 Diseases of pulp and periapical tissues	0.784	0.216	0.000
S68 Traumatic amputation of wrist and hand	0.783	0.217	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.782	0.218	0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.781	0.219	0.000
K26.5 Chronic or unspecified with perforation	0.778	0.222	0.000
K50-K52 Noninfective enteritis and colitis	0.776	0.224	0.000
Z08 Follow-up examination after treatment for malignant neoplasm	0.775	0.225	0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.772	0.228	0.000
S50-S59 Injuries to the elbow and forearm	0.772	0.228	0.000
I47.2 Ventricular tachycardia	0.771	0.229	0.000
N20.2 Calculus of kidney with calculus of ureter	0.770	0.230	0.000
H55-H59 Other disorders of eye and adnexa	0.769	0.231	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.768	0.232	0.000
E50-E64 Other nutritional deficiencies	0.768	0.232	0.000
D50-D53 Nutritional anaemias	0.768	0.232	0.000
L40-L45 Papulosquamous disorders	0.767	0.233	0.000
G51 Facial nerve disorders	0.766	0.234	0.000
K55-K64 Other diseases of intestines	0.764	0.236	0.000
T86 Failure and rejection of transplanted organs and tissues	0.763	0.237	0.000
Z92.6 Personal history of chemotherapy for neoplastic disease	0.762	0.238	0.000
Y83.1 Surgical operation with implant of artificial internal device	0.762	0.238	0.000
N99-N99 Other disorders of the genitourinary system	0.761	0.239	0.000
K26.4 Chronic or unspecified with haemorrhage	0.761	0.239	0.000
L89 Decubitus ulcer	0.761	0.239	0.000
L92.9 Granulomatous disorder of skin and subcutaneous tissue, unspecified	0.761	0.239	0.000
J45 Asthma	0.003	0.241	0.756
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.759	0.241	0.000
X20-X29 Contact with venomous animals and plants	0.759	0.241	0.000
G80-G83 Cerebral palsy and other paralytic syndromes	0.757	0.243	0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.756	0.244	0.000
D60-D64 Aplastic and other anaemias	0.755	0.245	0.000
T84.0 Mechanical complication of internal joint prosthesis	0.755	0.245	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.755	0.245	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.754	0.246	0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.753	0.247	0.000
E83 Disorders of mineral metabolism	0.753	0.247	0.000
L08 Other local infections of skin and subcutaneous tissue	0.752	0.248	0.000
N17.9 Acute renal failure, unspecified	0.750	0.250	0.000
E80 Disorders of porphyrin and bilirubin metabolism	0.750	0.250	0.000
N25-N29 Other disorders of kidney and ureter	0.750	0.250	0.000
L02 Cutaneous abscess, furuncle and carbuncle	0.750	0.250	0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts	0.748	0.251	0.000
K06.8 Other specified disorders of gingiva and edentulous alveolar ridge	0.747	0.253	0.000
N18.0 End-stage renal disease	0.746	0.254	0.000
L03.2 Cellulitis of face	0.746	0.254	0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.745	0.255	0.000
S64 Injury of nerves at wrist and hand level	0.745	0.255	0.000
N03.9 Unspecified	0.744	0.256	0.000
S90-S99 Injuries to the ankle and foot	0.743	0.257	0.000
S40-S49 Injuries to the shoulder and upper arm	0.743	0.257	0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]	0.743	0.257	0.000
V10-V19 Pedal cyclist injured in transport accident	0.743	0.257	0.000
Z93.3 Colostomy status	0.743	0.257	0.000
L03.3 Cellulitis of trunk	0.743	0.257	0.000
K61 Abscess of anal and rectal regions	0.742	0.258	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.740	0.260	0.000
I35.2 Aortic (valve) stenosis with insufficiency	0.738	0.262	0.000
C44 Other malignant neoplasms of skin	0.737	0.263	0.000
H10-H13 Disorders of conjunctiva	0.736	0.264	0.000
L81 Other disorders of pigmentation	0.735	0.265	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.734	0.265	0.000
H40 Glaucoma	0.734	0.266	0.000
V20-V29 Motorcycle rider injured in transport accident	0.731	0.269	0.000
J40-J47 Chronic lower respiratory diseases	0.008	0.270	0.722
W00-W19 Falls	0.729	0.271	0.000
H26.8 Other specified cataract	0.729	0.271	0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.727	0.272	0.000
K61.0 Anal abscess	0.727	0.273	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.727	0.273	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.726	0.274	0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.725	0.275	0.000
I33 Acute and subacute endocarditis	0.725	0.275	0.000
X60-X84 Intentional self-harm	0.725	0.275	0.000
Z93.2 Ileostomy status	0.725	0.275	0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.725	0.275	0.000
K12 Stomatitis and related lesions	0.724	0.276	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.724	0.276	0.000
Z60 Problems related to social environment	0.724	0.276	0.000
N17.0 Acute renal failure with tubular necrosis	0.723	0.277	0.000
K07.3 Anomalies of tooth position	0.722	0.278	0.000
N18.5 Chronic kidney disease, stage 5	0.722	0.278	0.000
C92 Myeloid leukaemia	0.722	0.278	0.000
F31 Bipolar affective disorder	0.721	0.279	0.000
K13 Other diseases of lip and oral mucosa	0.720	0.280	0.000
E21.3 Hyperparathyroidism, unspecified	0.719	0.281	0.000
I47.9 Paroxysmal tachycardia, unspecified	0.719	0.281	0.000
H53.8 Other visual disturbances	0.718	0.282	0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts	0.718	0.282	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283	0.000
K28 Gastrojejunal ulcer	0.717	0.283	0.000
K23 Disorders of oesophagus in diseases classified elsewhere	0.717	0.283	0.000
D45 Polycythaemia vera	0.717	0.283	0.000
T79-T79 Certain early complications of trauma	0.717	0.283	0.000
T33-T35 Frostbite	0.717	0.283	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.717	0.283	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.717	0.283	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.717	0.283	0.000
T00-T07 Injuries involving multiple body regions	0.717	0.283	0.000
S10-S19 Injuries to the neck	0.717	0.283	0.000
Y42.0 Glucocorticoids and synthetic analogs	0.715	0.285	0.000
E29 Testicular dysfunction	0.714	0.285	0.000
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified	0.715	0.285	0.000
J47 Bronchiectasis	0.001	0.286	0.713
F41 Other anxiety disorders	0.713	0.287	0.000
Y57.9 Drug or medicament, unspecified	0.713	0.287	0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.713	0.287	0.000
C40-C41 Malignant neoplasms of bone and articular cartilage	0.713	0.287	0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.713	0.287	0.000
N22 Calculus of urinary tract in diseases classified elsewhere	0.713	0.287	0.000
Y60-Y69 Misadventures to patients during surgical and medical care	0.711	0.289	0.000
G54 Nerve root and plexus disorders	0.711	0.289	0.000
N18.4 Chronic kidney disease, stage 4	0.711	0.289	0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.710	0.290	0.000
K56 Paralytic ileus and intestinal obstruction without hernia	0.710	0.290	0.000
L10-L14 Bullous disorders	0.710	0.290	0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.709	0.291	0.000
N20.9 Urinary calculus, unspecified	0.708	0.291	0.000
D50 Iron deficiency anaemia	0.708	0.292	0.000
F00-F09 Organic, including symptomatic, mental disorders	0.707	0.292	0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.707	0.293	0.000
D47.3 Essential (haemorrhagic) thrombocythaemia	0.707	0.293	0.000
T84.2 Mechanical complication of internal fixation device of other bones	0.706	0.294	0.000
S69 Other and unspecified injuries of wrist and hand	0.706	0.294	0.000
S67 Crushing injury of wrist and hand	0.706	0.294	0.000
S65 Injury of blood vessels at wrist and hand level	0.706	0.294	0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.706	0.294	0.000
S60 Superficial injury of wrist and hand	0.706	0.294	0.000
I35.0 Aortic (valve) stenosis	0.706	0.294	0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.705	0.295	0.000
Y35-Y36 Legal intervention and operations of war	0.705	0.295	0.000
Y10-Y34 Event of undetermined intent	0.705	0.295	0.000
Y00-Y09 Assault	0.705	0.295	0.000
X85-X99 Assault	0.705	0.295	0.000
X58-X59 Accidental exposure to other and unspecified factors	0.705	0.295	0.000
X50-X57 Overexertion, travel and privation	0.705	0.295	0.000
X40-X49 Accidental poisoning by and exposure to noxious substances	0.705	0.295	0.000
X30-X39 Exposure to forces of nature	0.705	0.295	0.000
X10-X19 Contact with heat and hot substances	0.705	0.295	0.000
X00-X09 Exposure to smoke, fire and flames	0.705	0.295	0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.705	0.295	0.000
W75-W84 Other accidental threats to breathing	0.705	0.295	0.000
W65-W74 Accidental drowning and submersion	0.705	0.295	0.000
W50-W64 Exposure to animate mechanical forces	0.705	0.295	0.000
V98-V99 Other and unspecified transport accidents	0.705	0.295	0.000
V95-V97 Air and space transport accidents	0.705	0.295	0.000
V90-V94 Water transport accidents	0.705	0.295	0.000
V80-V89 Other land transport accidents	0.705	0.295	0.000
V70-V79 Bus occupant injured in transport accident	0.705	0.295	0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.705	0.295	0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.705	0.295	0.000
V40-V49 Car occupant injured in transport accident	0.705	0.295	0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.705	0.295	0.000
V01-V09 Pedestrian injured in transport accident	0.705	0.295	0.000
E40-E46 Malnutrition	0.704	0.296	0.000
Chapter XXII Codes for special purposes	0.704	0.296	0.000
D10-D36 Benign neoplasms	0.704	0.296	0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts	0.704	0.296	0.000
K26.7 Chronic without haemorrhage or perforation	0.703	0.296	0.000
K26.6 Chronic or unspecified with both haemorrhage and perforation	0.703	0.296	0.000
K26.2 Acute with both haemorrhage and perforation	0.703	0.296	0.000
K26.1 Acute with perforation	0.703	0.296	0.000
K26.0 Acute with haemorrhage	0.703	0.296	0.000
Z13 Special screening examination for other diseases and disorders	0.703	0.297	0.000
Z89 Acquired absence of limb	0.703	0.297	0.000
Y83.4 Other reconstructive surgery	0.702	0.298	0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.702	0.298	0.000
I60-I69 Cerebrovascular diseases	0.702	0.298	0.000
N18.8 Other chronic renal failure	0.701	0.299	0.000
N18.1 Chronic kidney disease, stage 1	0.701	0.299	0.000
H26.2 Complicated cataract	0.701	0.299	0.000
E21.0 Primary hyperparathyroidism	0.701	0.299	0.000
I30 Acute pericarditis	0.700	0.300	0.000
H46-H48 Disorders of optic nerve and visual pathways	0.700	0.300	0.000
Z08.0 Follow-up examination after surgery for malignant neoplasm	0.700	0.300	0.000
I46 Cardiac arrest	0.699	0.301	0.000
N70-N77 Inflammatory diseases of female pelvic organs	0.698	0.302	0.000
T87 Complications peculiar to reattachment and amputation	0.698	0.302	0.000
T80 Complications following infusion, transfusion and therapeutic injection	0.698	0.302	0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere	0.694	0.306	0.000
L95 Vasculitis limited to skin, not elsewhere classified	0.694	0.306	0.000
L94 Other localised connective tissue disorders	0.694	0.306	0.000
L93 Lupus erythematosus	0.694	0.306	0.000
L87 Transepidermal elimination disorders	0.694	0.306	0.000
L88 Pyoderma gangrenosum	0.694	0.306	0.000
L86 Keratoderma in diseases classified elsewhere	0.694	0.306	0.000
L84 Corns and callosities	0.694	0.306	0.000
L83 Acanthosis nigricans	0.694	0.306	0.000
L80 Vitiligo	0.694	0.306	0.000
S61.7 Multiple open wounds of wrist and hand	0.693	0.307	0.000
S22 Fracture of rib(s), sternum and thoracic spine	0.693	0.307	0.000
D41.4 Bladder	0.693	0.307	0.000
L50-L54 Urticaria and erythema	0.691	0.309	0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.690	0.310	0.000
K10 Other diseases of jaws	0.689	0.311	0.000
K09 Cysts of oral region, not elsewhere classified	0.689	0.311	0.000
K03 Other diseases of hard tissues of teeth	0.689	0.311	0.000
K00 Disorders of tooth development and eruption	0.689	0.311	0.000
K29.3 Chronic superficial gastritis	0.689	0.311	0.000
T88 Other complications of surgical and medical care, not elsewhere classified	0.687	0.312	0.000
Z94.0 Kidney transplant status	0.687	0.312	0.000
S61.1 Open wound of finger(s) with damage to nail	0.687	0.313	0.000
L60-L75 Disorders of skin appendages	0.687	0.313	0.000
K29.1 Other acute gastritis	0.685	0.315	0.000
Y40 Systemic antibiotics	0.685	0.315	0.000
E88 Other metabolic disorders	0.684	0.315	0.000
E85 Amyloidosis	0.684	0.315	0.000
E84 Cystic fibrosis	0.684	0.315	0.000
E79 Disorders of purine and pyrimidine metabolism	0.684	0.315	0.000
E77 Disorders of glycoprotein metabolism	0.684	0.315	0.000
E76 Disorders of glycosaminoglycan metabolism	0.684	0.315	0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.684	0.315	0.000
E74 Other disorders of carbohydrate metabolism	0.684	0.315	0.000
E73 Lactose intolerance	0.684	0.315	0.000
E72 Other disorders of amino-acid metabolism	0.684	0.315	0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.684	0.315	0.000
E70 Disorders of aromatic amino-acid metabolism	0.684	0.315	0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.684	0.315	0.000
C20 Malignant neoplasm of rectum	0.682	0.318	0.000
T85.4 Mechanical complication of breast prosthesis and implant	0.682	0.318	0.000
Chapter I Certain infectious and parasitic diseases	0.682	0.318	0.000
K26.3 Acute without haemorrhage or perforation	0.682	0.318	0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.681	0.319	0.000
C95 Leukaemia of unspecified cell type	0.681	0.319	0.000
C94 Other leukaemias of specified cell type	0.681	0.319	0.000
C93 Monocytic leukaemia	0.681	0.319	0.000
C88 Malignant immunoproliferative diseases	0.681	0.319	0.000
C86 Other specified types of T/NK-cell lymphoma	0.681	0.319	0.000
C84 Peripheral and cutaneous T-cell lymphomas	0.681	0.319	0.000
C81 Hodgkin's disease	0.681	0.319	0.000
F99-F99 Unspecified mental disorder	0.678	0.321	0.000
C67.2 Lateral wall of bladder	0.678	0.322	0.000
K56.6 Other and unspecified intestinal obstruction	0.678	0.322	0.000
K22.5 Diverticulum of oesophagus, acquired	0.677	0.322	0.000
K22.3 Perforation of oesophagus	0.677	0.322	0.000
K22.0 Achalasia of cardia	0.677	0.322	0.000
Z11 Special screening examination for infectious and parasitic diseases	0.677	0.323	0.000
K07.6 Temporomandibular joint disorders	0.677	0.323	0.000
Z92.2 Personal history of long-term (current) use of other medicaments	0.676	0.324	0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction	0.676	0.324	0.000
L05 Pilonidal cyst	0.675	0.325	0.000
F41.2 Mixed anxiety and depressive disorder	0.675	0.325	0.000
G70-G73 Diseases of myoneural junction and muscle	0.675	0.325	0.000
G00-G09 Inflammatory diseases of the central nervous system	0.675	0.325	0.000
K51 Ulcerative colitis	0.675	0.325	0.000
Z94.8 Other transplanted organ and tissue status	0.675	0.325	0.000
L08.8 Other specified local infections of skin and subcutaneous tissue	0.674	0.326	0.000
I71 Aortic aneurysm and dissection	0.674	0.326	0.000
T78 Adverse effects, not elsewhere classified	0.673	0.327	0.000
I44.1 Atrioventricular block, second degree	0.673	0.327	0.000
M15-M19 Arthrosis	0.673	0.327	0.000
D46 Myelodysplastic syndromes	0.672	0.327	0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.672	0.327	0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.672	0.327	0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.672	0.327	0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.672	0.327	0.000
I42 Cardiomyopathy	0.672	0.328	0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.671	0.329	0.000
K11 Diseases of salivary glands	0.671	0.329	0.000
K29.9 Gastroduodenitis, unspecified	0.670	0.329	0.000
K29.4 Chronic atrophic gastritis	0.670	0.329	0.000
K29.2 Alcoholic gastritis	0.670	0.329	0.000
C83 Diffuse non-Hodgkin's lymphoma	0.670	0.330	0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft	0.669	0.331	0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts	0.669	0.331	0.000
T84.3 Mechanical complication of other bone devices, implants and grafts	0.669	0.331	0.000
L04 Acute lymphadenitis	0.669	0.331	0.000
L01 Impetigo	0.669	0.331	0.000
L00 Staphylococcal scalded skin syndrome	0.669	0.331	0.000
D09 Carcinoma in situ of other and unspecified sites	0.669	0.331	0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts	0.668	0.332	0.000
Z08.9 Follow-up examination after unspecified treatment for malignant neoplasm	0.668	0.332	0.000
C44.3 Skin of other and unspecified parts of face	0.668	0.332	0.000
C64 Malignant neoplasm of kidney, except renal pelvis	0.667	0.333	0.000
K02 Dental caries	0.667	0.333	0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.667	0.333	0.000
D50.8 Other iron deficiency anaemias	0.666	0.334	0.000
E28 Ovarian dysfunction	0.665	0.334	0.000
G59 Mononeuropathy in diseases classified elsewhere	0.665	0.335	0.000
G58 Other mononeuropathies	0.665	0.335	0.000
G53 Cranial nerve disorders in diseases classified elsewhere	0.665	0.335	0.000
G52 Disorders of other cranial nerves	0.665	0.335	0.000
C68 Malignant neoplasm of other and unspecified urinary organs	0.665	0.335	0.000
C66 Malignant neoplasm of ureter	0.665	0.335	0.000
C65 Malignant neoplasm of renal pelvis	0.665	0.335	0.000
H54 Blindness and low vision	0.664	0.336	0.000
K25.9 Unspecified as acute or chronic, without haemorrhage or perforation	0.664	0.336	0.000
L91 Hypertrophic disorders of skin	0.663	0.337	0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis	0.662	0.338	0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.661	0.339	0.000
C51-C58 Malignant neoplasms of female genital organs	0.661	0.339	0.000
L03.9 Cellulitis, unspecified	0.661	0.339	0.000
G56.9 Mononeuropathy of upper limb, unspecified	0.661	0.339	0.000
G56.8 Other mononeuropathies of upper limb	0.661	0.339	0.000
G56.4 Causalgia	0.661	0.339	0.000
G56.3 Lesion of radial nerve	0.661	0.339	0.000
G56.1 Other lesions of median nerve	0.661	0.339	0.000
M50-M54 Other dorsopathies	0.661	0.339	0.000
E87.5 Hyperkalaemia	0.661	0.339	0.000
E23 Hypofunction and other disorders of pituitary gland	0.660	0.340	0.000
M19 Other arthrosis	0.660	0.340	0.000
M05-M14 Inflammatory polyarthropathies	0.660	0.340	0.000
S27 Injury of other and unspecified intrathoracic organs	0.659	0.340	0.000
G90-G99 Other disorders of the nervous system	0.659	0.341	0.000
Z90 Acquired absence of organs, not elsewhere classified	0.658	0.342	0.000
L92.3 Foreign body granuloma of skin and subcutaneous tissue	0.658	0.342	0.000
Chapter VIII Diseases of the ear and mastoid process	0.658	0.342	0.000
Y59 Other and unspecified vaccines and biological substances	0.657	0.343	0.000
Y58 Bacterial vaccines	0.657	0.343	0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.657	0.343	0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.657	0.343	0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.657	0.343	0.000
Y53 Agents primarily affecting the gastro-intestinal system	0.657	0.343	0.000
Y52 Agents primarily affecting the cardiovascular system	0.657	0.343	0.000
Y50 Central nervous system stimulants, not elsewhere classified	0.657	0.343	0.000
Y49 Psychotropic drugs, not elsewhere classified	0.657	0.343	0.000
Y48 Anaesthetics and therapeutic gases	0.657	0.343	0.000
Y47 Sedatives, hypnotics and antianxiety drugs	0.657	0.343	0.000
Y46 Antiepileptics and anti-Parkinsonism drugs	0.657	0.343	0.000
Y44 Agents primarily affecting blood constituents	0.657	0.343	0.000
Y41 Other systemic anti-infectives and antiparasitics	0.657	0.343	0.000
C85.7 Other specified types of non-Hodgkin's lymphoma	0.657	0.343	0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma	0.657	0.343	0.000
C85.0 Lymphosarcoma	0.657	0.343	0.000
C90 Multiple myeloma and malignant plasma cell neoplasms	0.657	0.343	0.000
Z08.7 Follow-up examination after combined treatment for malignant neoplasm	0.656	0.343	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.655	0.344	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.654	0.346	0.000
H53.9 Visual disturbance, unspecified	0.653	0.347	0.000
Z85 Personal history of malignant neoplasm	0.653	0.347	0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.653	0.347	0.000
Z60.2 Living alone	0.652	0.348	0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.652	0.348	0.000
F80-F89 Disorders of psychological development	0.652	0.348	0.000
F70-F79 Mental retardation	0.652	0.348	0.000
F60-F69 Disorders of adult personality and behaviour	0.652	0.348	0.000
Y83.2 Surgical operation with anastomosis, bypass or graft	0.652	0.348	0.000
L43 Lichen planus	0.651	0.349	0.000
Y42.7 Androgens and anabolic congeners	0.651	0.349	0.000
N21 Calculus of lower urinary tract	0.650	0.349	0.000
G51.0 Bell's palsy	0.650	0.350	0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified	0.650	0.350	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.650	0.350	0.000
E34 Other endocrine disorders	0.650	0.350	0.000
E32 Diseases of thymus	0.650	0.350	0.000
E31 Polyglandular dysfunction	0.650	0.350	0.000
E30 Disorders of puberty, not elsewhere classified	0.650	0.350	0.000
E27 Other disorders of adrenal gland	0.650	0.350	0.000
E26 Hyperaldosteronism	0.650	0.350	0.000
E25 Adrenogenital disorders	0.650	0.350	0.000
E24 Cushing's syndrome	0.650	0.350	0.000
E22 Hyperfunction of pituitary gland	0.650	0.350	0.000
E20 Hypoparathyroidism	0.650	0.350	0.000
D23 Other benign neoplasms of skin	0.650	0.350	0.000
Z97 Presence of other devices	0.650	0.350	0.000
Z84 Family history of other conditions	0.650	0.350	0.000
Z81 Family history of mental and behavioural disorders	0.650	0.350	0.000
H52 Disorders of refraction and accommodation	0.649	0.351	0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.649	0.351	0.000
E87.6 Hypokalaemia	0.648	0.352	0.000
K14.8 Other diseases of tongue	0.648	0.352	0.000
I00-I02 Acute rheumatic fever	0.647	0.353	0.000
Z95.3 Presence of xenogenic heart valve	0.647	0.353	0.000
K04.7 Periapical abscess without sinus	0.646	0.354	0.000
H28 Cataract and other disorders of lens in diseases classified elsewhere	0.646	0.354	0.000
H27 Other disorders of lens	0.646	0.354	0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.646	0.354	0.000
K27 Peptic ulcer, site unspecified	0.645	0.354	0.000
N10-N16 Renal tubulo-interstitial diseases	0.645	0.355	0.000
E83.5 Disorders of calcium metabolism	0.645	0.355	0.000
H50 Other strabismus	0.643	0.357	0.000
G30-G32 Other degenerative diseases of the nervous system	0.641	0.359	0.000
K05.1 Chronic gingivitis	0.641	0.359	0.000
Y51 Drugs primarily affecting the autonomic nervous system	0.639	0.360	0.000
L85.8 Other specified epidermal thickening	0.638	0.361	0.000
S68.1 Traumatic amputation of other single finger (complete)(partial)	0.638	0.362	0.000
Z13.9 Special screening examination, unspecified	0.637	0.363	0.000
K22.6 Gastro-oesophageal laceration-haemorrhage syndrome	0.637	0.363	0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.635	0.365	0.000
L03.8 Cellulitis of other sites	0.635	0.365	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations