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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs114477071
log Bayes Factor = 15.5877
Chromosome 6   position 14,938,860  (GRCh37) Explore rs114477071 on Ensembl!
Variant rs114477071 is part of Cluster X0043

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
I30-I52 Other forms of heart disease
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.999 0.001 0.000
Chapter II Neoplasms
0.998 0.002 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.996 0.004 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.995 0.005 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.995 0.005 0.000
C34 Malignant neoplasm of bronchus and lung
0.993 0.007 0.000
Chapter XXI Factors influencing health status and contact with health services
0.993 0.007 0.000
M70-M79 Other soft tissue disorders
0.992 0.008 0.000
D70 Agranulocytosis
0.991 0.009 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.991 0.009 0.000
Chapter VIII Diseases of the ear and mastoid process
0.990 0.010 0.000
C15-C26 Malignant neoplasms of digestive organs
0.986 0.014 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.985 0.015 0.000
I51 Complications and ill-defined descriptions of heart disease
0.984 0.016 0.000
I80 Phlebitis and thrombophlebitis
0.982 0.018 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.979 0.021 0.000
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities
0.973 0.027 0.000
H65-H75 Diseases of middle ear and mastoid
0.967 0.033 0.000
C18 Malignant neoplasm of colon
0.964 0.036 0.000
S80-S89 Injuries to the knee and lower leg
0.960 0.040 0.000
I47 Paroxysmal tachycardia
0.959 0.041 0.000
C34.1 Upper lobe, bronchus or lung
0.958 0.042 0.000
Chapter XX External causes of morbidity and mortality
0.957 0.043 0.000
Chapter I Certain infectious and parasitic diseases
0.956 0.044 0.000
I51.7 Cardiomegaly
0.956 0.044 0.000
T81 Complications of procedures, not elsewhere classified
0.954 0.046 0.000
C34.9 Bronchus or lung, unspecified
0.954 0.046 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.949 0.051 0.000
I20-I25 Ischaemic heart diseases
0.948 0.052 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.945 0.055 0.000
Z90.4 Acquired absence of other parts of digestive tract
0.943 0.057 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.933 0.067 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.933 0.067 0.000
Chapter X Diseases of the respiratory system
0.932 0.068 0.000
I45 Other conduction disorders
0.925 0.075 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.921 0.079 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.915 0.085 0.000
Z92 Personal history of medical treatment
0.914 0.086 0.000
M75 Shoulder lesions
0.910 0.090 0.000
Z92.1 Personal history of long-term (current) use of anticoagulants
0.907 0.093 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.907 0.093 0.000
I47.2 Ventricular tachycardia
0.906 0.094 0.000
H65 Nonsuppurative otitis media
0.903 0.097 0.000
C34.3 Lower lobe, bronchus or lung
0.896 0.104 0.000
C18.7 Sigmoid colon
0.896 0.104 0.000
M77 Other enthesopathies
0.893 0.107 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.891 0.109 0.000
I50 Heart failure
0.890 0.110 0.000
D68 Other coagulation defects
0.889 0.111 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.887 0.113 0.000
M79.8 Other specified soft tissue disorders
0.886 0.114 0.000
H90-H95 Other disorders of ear
0.882 0.118 0.000
J95-J99 Other diseases of the respiratory system
0.882 0.118 0.000
T81.4 Infection following a procedure, not elsewhere classified
0.875 0.125 0.000
D60-D64 Aplastic and other anaemias
0.872 0.128 0.000
Chapter V Mental and behavioural disorders
0.871 0.129 0.000
I42 Cardiomyopathy
0.869 0.131 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.867 0.133 0.000
I21 Acute myocardial infarction
0.866 0.134 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.865 0.135 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.863 0.137 0.000
S70-S79 Injuries to the hip and thigh
0.862 0.138 0.000
A30-A49 Other bacterial diseases
0.861 0.139 0.000
M20-M25 Other joint disorders
0.860 0.140 0.000
I44 Atrioventricular and left bundle-branch block
0.857 0.143 0.000
I50.1 Left ventricular failure
0.856 0.144 0.000
J09-J18 Influenza and pneumonia
0.855 0.145 0.000
I51.9 Heart disease, unspecified
0.855 0.145 0.000
I84 Haemorrhoids
0.855 0.145 0.000
Z94 Transplanted organ and tissue status
0.853 0.147 0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]
0.851 0.149 0.000
C18.9 Colon, unspecified
0.851 0.149 0.000
J98 Other respiratory disorders
0.850 0.150 0.000
I34 Nonrheumatic mitral valve disorders
0.848 0.152 0.000
T81.8 Other complications of procedures, not elsewhere classified
0.844 0.156 0.000
H74 Other disorders of middle ear and mastoid
0.839 0.161 0.000
I45.1 Other and unspecified right bundle-branch block
0.837 0.163 0.000
Z60 Problems related to social environment
0.836 0.164 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.834 0.166 0.000
M75.1 Rotator cuff syndrome
0.833 0.167 0.000
M05-M14 Inflammatory polyarthropathies
0.833 0.167 0.000
I20 Angina pectoris
0.831 0.169 0.000
Chapter XXII Codes for special purposes
0.830 0.170 0.000
H65.3 Chronic mucoid otitis media
0.829 0.171 0.000
S00-S09 Injuries to the head
0.829 0.171 0.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system
0.828 0.172 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.826 0.174 0.000
Z80 Family history of malignant neoplasm
0.826 0.174 0.000
S40-S49 Injuries to the shoulder and upper arm
0.822 0.178 0.000
S80 Superficial injury of lower leg
0.821 0.179 0.000
I49 Other cardiac arrhythmias
0.821 0.179 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.816 0.184 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.813 0.187 0.000
H80-H83 Diseases of inner ear
0.810 0.190 0.000
I20.0 Unstable angina
0.810 0.190 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.809 0.191 0.000
B15-B19 Viral hepatitis
0.807 0.193 0.000
I80.9 Phlebitis and thrombophlebitis of unspecified site
0.807 0.193 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.806 0.194 0.000
M23 Internal derangement of knee
0.806 0.194 0.000
T84.3 Mechanical complication of other bone devices, implants and grafts
0.806 0.194 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.805 0.195 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.804 0.196 0.000
M79.85 Other specified soft tissue disorders (Pelvic region and thigh)
0.803 0.197 0.000
V10-V19 Pedal cyclist injured in transport accident
0.800 0.200 0.000
W00-W19 Falls
0.800 0.200 0.000
J98.4 Other disorders of lung
0.800 0.200 0.000
Z87 Personal history of other diseases and conditions
0.800 0.200 0.000
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified
0.796 0.204 0.000
Z22 Carrier of infectious disease
0.796 0.204 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.796 0.204 0.000
M23.8 Other internal derangements of knee
0.794 0.206 0.000
W20-W49 Exposure to inanimate mechanical forces
0.794 0.206 0.000
S50-S59 Injuries to the elbow and forearm
0.789 0.211 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.788 0.212 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.787 0.213 0.000
M77.9 Enthesopathy, unspecified
0.786 0.213 0.000
Z60.2 Living alone
0.786 0.214 0.000
D68.8 Other specified coagulation defects
0.784 0.216 0.000
H73 Other disorders of tympanic membrane
0.784 0.216 0.000
Z92.0 Personal history of contraception
0.783 0.217 0.000
T79-T79 Certain early complications of trauma
0.782 0.218 0.000
S81 Open wound of lower leg
0.782 0.218 0.000
I45.2 Bifascicular block
0.782 0.218 0.000
Z94.8 Other transplanted organ and tissue status
0.780 0.219 0.000
M40-M43 Deforming dorsopathies
0.780 0.220 0.000
D73 Diseases of spleen
0.775 0.225 0.000
M60-M63 Disorders of muscles
0.775 0.225 0.000
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified
0.775 0.225 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.774 0.226 0.000
Z90.3 Acquired absence of part of stomach
0.774 0.226 0.000
Z13 Special screening examination for other diseases and disorders
0.773 0.227 0.000
M80-M85 Disorders of bone density and structure
0.772 0.228 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.770 0.229 0.000
D68.6 Other Thrombophilia
0.770 0.230 0.000
H91 Other hearing loss
0.769 0.231 0.000
D55-D59 Haemolytic anaemias
0.768 0.232 0.000
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.768 0.232 0.000
J98.0 Diseases of bronchus, not elsewhere classified
0.767 0.233 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.767 0.233 0.000
Z03 Medical observation and evaluation for suspected diseases and conditions
0.765 0.235 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.765 0.235 0.000
B35-B49 Mycoses
0.764 0.236 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.763 0.237 0.000
I44.0 Atrioventricular block, first degree
0.762 0.238 0.000
M71 Other bursopathies
0.760 0.240 0.000
B25-B34 Other viral diseases
0.760 0.240 0.000
X60-X84 Intentional self-harm
0.759 0.241 0.000
A00-A09 Intestinal infectious diseases
0.759 0.241 0.000
M75.2 Bicipital tendinitis
0.758 0.242 0.000
I47.1 Supraventricular tachycardia
0.757 0.243 0.000
D45 Polycythaemia vera
0.757 0.243 0.000
S89 Other and unspecified injuries of lower leg
0.756 0.244 0.000
M76 Enthesopathies of lower limb, excluding foot
0.756 0.244 0.000
C18.5 Splenic flexure
0.756 0.244 0.000
C18.0 Caecum
0.755 0.245 0.000
A80-A89 Viral infections of the central nervous system
0.755 0.245 0.000
Z81 Family history of mental and behavioural disorders
0.755 0.245 0.000
Z95.2 Presence of prosthetic heart valve
0.755 0.245 0.000
H66 Suppurative and unspecified otitis media
0.753 0.247 0.000
S82 Fracture of lower leg, including ankle
0.753 0.247 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.752 0.248 0.000
I47.0 Reentry ventricular arrhythmia
0.751 0.249 0.000
Q60-Q64 Congenital malformations of the urinary system
0.751 0.249 0.000
I51.8 Other ill-defined heart diseases
0.749 0.251 0.000
Z90.2 Acquired absence of lung [part of]
0.749 0.251 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.749 0.251 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.748 0.252 0.000
M86-M90 Other osteopathies
0.746 0.254 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.745 0.255 0.000
T84.2 Mechanical complication of internal fixation device of other bones
0.745 0.255 0.000
I86 Varicose veins of other sites
0.744 0.256 0.000
A41 Other septicaemia
0.744 0.256 0.000
H65.9 Nonsuppurative otitis media, unspecified
0.744 0.256 0.000
Z87.0 Personal history of diseases of the respiratory system
0.744 0.256 0.000
H72 Perforation of tympanic membrane
0.743 0.257 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.742 0.258 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.742 0.258 0.000
S72 Fracture of femur
0.741 0.259 0.000
Z80.7 Family history of malignant neoplasms of lymphoid, haematopoietic and related tissues
0.740 0.260 0.000
S90-S99 Injuries to the ankle and foot
0.739 0.261 0.000
M79.7 Fibromyalgia
0.739 0.261 0.000
I80.8 Phlebitis and thrombophlebitis of other sites
0.738 0.262 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.737 0.263 0.000
M79.87 Other specified soft tissue disorders (Ankle and foot)
0.736 0.263 0.000
D68.5 Primary Thrombophilia
0.735 0.265 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.735 0.265 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.734 0.266 0.000
I42.0 Dilated cardiomyopathy
0.733 0.267 0.000
J84 Other interstitial pulmonary diseases
0.731 0.269 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.730 0.269 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.730 0.270 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.729 0.270 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.728 0.272 0.000
M79.80 Other specified soft tissue disorders (Multiple sites)
0.728 0.272 0.000
S10-S19 Injuries to the neck
0.727 0.273 0.000
T86 Failure and rejection of transplanted organs and tissues
0.726 0.274 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.724 0.276 0.000
T81.9 Unspecified complication of procedure
0.723 0.277 0.000
M10 Gout
0.723 0.277 0.000
C92 Myeloid leukaemia
0.722 0.278 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.722 0.278 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.721 0.279 0.000
Z92.4 Personal history of major surgery, not elsewhere classified
0.721 0.279 0.000
M79.1 Myalgia
0.721 0.279 0.000
C20 Malignant neoplasm of rectum
0.721 0.279 0.000
W50-W64 Exposure to animate mechanical forces
0.719 0.281 0.000
C18.4 Transverse colon
0.718 0.282 0.000
C34.0 Main bronchus
0.718 0.282 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I52 Other heart disorders in diseases classified elsewhere
0.717 0.283 0.000
I48 Atrial fibrillation and flutter
0.717 0.283 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.717 0.283 0.000
I41 Myocarditis in diseases classified elsewhere
0.717 0.283 0.000
I40 Acute myocarditis
0.717 0.283 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.717 0.283 0.000
I37 Pulmonary valve disorders
0.717 0.283 0.000
I36 Nonrheumatic tricuspid valve disorders
0.717 0.283 0.000
I33 Acute and subacute endocarditis
0.717 0.283 0.000
I32 Pericarditis in diseases classified elsewhere
0.717 0.283 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
Z22.3 Carrier of other specified bacterial diseases
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.716 0.284 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.716 0.284 0.000
Q24 Other congenital malformations of heart
0.715 0.285 0.000
M77.0 Medial epicondylitis
0.715 0.285 0.000
M91-M94 Chondropathies
0.714 0.286 0.000
M00-M03 Infectious arthropathies
0.714 0.286 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.713 0.286 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.713 0.286 0.000
C32 Malignant neoplasm of larynx
0.713 0.286 0.000
C31 Malignant neoplasm of accessory sinuses
0.713 0.286 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.713 0.286 0.000
C37 Malignant neoplasm of thymus
0.713 0.286 0.000
C33 Malignant neoplasm of trachea
0.713 0.286 0.000
I87 Other disorders of veins
0.713 0.287 0.000
Q50-Q56 Congenital malformations of genital organs
0.713 0.287 0.000
D74 Methaemoglobinaemia
0.713 0.287 0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.713 0.287 0.000
D71 Functional disorders of polymorphonuclear neutrophils
0.713 0.287 0.000
I21.4 Acute subendocardial myocardial infarction
0.713 0.287 0.000
M35 Other systemic involvement of connective tissue
0.713 0.287 0.000
T81.7 Vascular complications following a procedure, not elsewhere classified
0.713 0.287 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.712 0.287 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.712 0.288 0.000
C34.8 Overlapping lesion of bronchus and lung
0.712 0.288 0.000
C34.2 Middle lobe, bronchus or lung
0.712 0.288 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.711 0.289 0.000
I88 Nonspecific lymphadenitis
0.710 0.289 0.000
I81 Portal vein thrombosis
0.710 0.289 0.000
M77.91 Enthesopathy, unspecified (Shoulder region)
0.710 0.290 0.000
I34.0 Mitral (valve) insufficiency
0.710 0.290 0.000
Z13.0 Special screening examination for diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.709 0.291 0.000
Q80-Q89 Other congenital malformations
0.708 0.292 0.000
Q21 Congenital malformations of cardiac septa
0.708 0.292 0.000
I25 Chronic ischaemic heart disease
0.708 0.292 0.000
I49.1 Atrial premature depolarisation
0.708 0.292 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.707 0.293 0.000
C21 Malignant neoplasm of anus and anal canal
0.707 0.293 0.000
C17 Malignant neoplasm of small intestine
0.707 0.293 0.000
C23 Malignant neoplasm of gallbladder
0.707 0.293 0.000
S42 Fracture of shoulder and upper arm
0.706 0.294 0.000
T87 Complications peculiar to reattachment and amputation
0.706 0.294 0.000
H93 Other disorders of ear, not elsewhere classified
0.706 0.294 0.000
I51.6 Cardiovascular disease, unspecified
0.706 0.294 0.000
I51.5 Myocardial degeneration
0.706 0.294 0.000
I51.4 Myocarditis, unspecified
0.706 0.294 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.706 0.294 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.706 0.294 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.706 0.294 0.000
I51.0 Cardiac septal defect, acquired
0.706 0.294 0.000
I84.9 Unspecified haemorrhoids without complication
0.706 0.294 0.000
M75.3 Calcific tendinitis of shoulder
0.706 0.294 0.000
Z63 Other problems related to primary support group, including family circumstances
0.706 0.294 0.000
Q00-Q07 Congenital malformations of the nervous system
0.705 0.295 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.705 0.295 0.000
I24 Other acute ischaemic heart diseases
0.705 0.295 0.000
Z80.9 Family history of malignant neoplasm, unspecified
0.704 0.296 0.000
C16 Malignant neoplasm of stomach
0.703 0.297 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.703 0.297 0.000
M79.84 Other specified soft tissue disorders (Hand)
0.703 0.297 0.000
S09 Other and unspecified injuries of head
0.703 0.297 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.703 0.297 0.000
Z89 Acquired absence of limb
0.702 0.298 0.000
Z84 Family history of other conditions
0.702 0.298 0.000
I84.6 Residual haemorrhoidal skin tags
0.702 0.298 0.000
M79.82 Other specified soft tissue disorders (Upper arm)
0.702 0.298 0.000
D80-D89 Certain disorders involving the immune mechanism
0.702 0.298 0.000
S82.6 Fracture of lateral malleolus
0.700 0.300 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.700 0.300 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.700 0.300 0.000
C18.6 Descending colon
0.699 0.301 0.000
J00-J06 Acute upper respiratory infections
0.699 0.301 0.000
H90 Conductive and sensorineural hearing loss
0.697 0.303 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.697 0.303 0.000
I44.1 Atrioventricular block, second degree
0.697 0.303 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
0.697 0.303 0.000
V80-V89 Other land transport accidents
0.695 0.305 0.000
F17.2 Dependence syndrome
0.694 0.306 0.000
H69 Other disorders of Eustachian tube
0.693 0.306 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.693 0.307 0.000
H70 Mastoiditis and related conditions
0.693 0.307 0.000
H68 Eustachian salpingitis and obstruction
0.693 0.307 0.000
H67 Otitis media in diseases classified elsewhere
0.693 0.307 0.000
S70 Superficial injury of hip and thigh
0.693 0.307 0.000
Q27 Other congenital malformations of peripheral vascular system
0.692 0.307 0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts
0.692 0.307 0.000
Z03.8 Observation for other suspected diseases and conditions
0.692 0.308 0.000
C18.8 Overlapping lesion of colon
0.691 0.309 0.000
C18.1 Appendix
0.691 0.309 0.000
Z88.6 Personal history of allergy to analgesic agent
0.690 0.310 0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure
0.690 0.310 0.000
Y40 Systemic antibiotics
0.690 0.310 0.000
H91.9 Hearing loss, unspecified
0.688 0.311 0.000
A49 Bacterial infection of unspecified site
0.688 0.312 0.000
S88 Traumatic amputation of lower leg
0.688 0.312 0.000
S87 Crushing injury of lower leg
0.688 0.312 0.000
S86 Injury of muscle and tendon at lower leg level
0.688 0.312 0.000
S85 Injury of blood vessels at lower leg level
0.688 0.312 0.000
S84 Injury of nerves at lower leg level
0.688 0.312 0.000
V18 Pedal cyclist injured in noncollision transport accident
0.688 0.312 0.000
I47.9 Paroxysmal tachycardia, unspecified
0.687 0.313 0.000
I31 Other diseases of pericardium
0.687 0.313 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.686 0.314 0.000
Y35-Y36 Legal intervention and operations of war
0.686 0.314 0.000
Y10-Y34 Event of undetermined intent
0.686 0.314 0.000
Y00-Y09 Assault
0.686 0.314 0.000
X85-X99 Assault
0.686 0.314 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.686 0.314 0.000
X50-X57 Overexertion, travel and privation
0.686 0.314 0.000
X30-X39 Exposure to forces of nature
0.686 0.314 0.000
X20-X29 Contact with venomous animals and plants
0.686 0.314 0.000
X10-X19 Contact with heat and hot substances
0.686 0.314 0.000
X00-X09 Exposure to smoke, fire and flames
0.686 0.314 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.686 0.314 0.000
W75-W84 Other accidental threats to breathing
0.686 0.314 0.000
W65-W74 Accidental drowning and submersion
0.686 0.314 0.000
V98-V99 Other and unspecified transport accidents
0.686 0.314 0.000
V95-V97 Air and space transport accidents
0.686 0.314 0.000
V90-V94 Water transport accidents
0.686 0.314 0.000
V70-V79 Bus occupant injured in transport accident
0.686 0.314 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.686 0.314 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.686 0.314 0.000
V40-V49 Car occupant injured in transport accident
0.686 0.314 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.686 0.314 0.000
V01-V09 Pedestrian injured in transport accident
0.686 0.314 0.000
D68.9 Coagulation defect, unspecified
0.686 0.314 0.000
B99-B99 Other infectious diseases
0.685 0.314 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.685 0.314 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.685 0.314 0.000
B65-B83 Helminthiases
0.685 0.314 0.000
B50-B64 Protozoal diseases
0.685 0.314 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.685 0.314 0.000
A75-A79 Rickettsioses
0.685 0.314 0.000
A70-A74 Other diseases caused by chlamydiae
0.685 0.314 0.000
A65-A69 Other spirochaetal diseases
0.685 0.314 0.000
A20-A28 Certain zoonotic bacterial diseases
0.685 0.314 0.000
A15-A19 Tuberculosis
0.685 0.314 0.000
H74.4 Polyp of middle ear
0.685 0.315 0.000
D64 Other anaemias
0.685 0.315 0.000
S80.0 Contusion of knee
0.685 0.315 0.000
Chapter VII Diseases of the eye and adnexa
0.685 0.315 0.000
S81.9 Open wound of lower leg, part unspecified
0.684 0.315 0.000
W29 Contact with other powered hand tools and household machinery
0.684 0.316 0.000
T81.6 Acute reaction to foreign substance accidentally left during a procedure
0.684 0.316 0.000
T81.1 Shock during or resulting from a procedure, not elsewhere classified
0.684 0.316 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.683 0.317 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.682 0.318 0.000
I05-I09 Chronic rheumatic heart diseases
0.681 0.318 0.000
I49.9 Cardiac arrhythmia, unspecified
0.681 0.319 0.000
D62 Acute posthaemorrhagic anaemia
0.681 0.319 0.000
I30 Acute pericarditis
0.680 0.319 0.000
M77.4 Metatarsalgia
0.680 0.319 0.000
F30-F39 Mood [affective] disorders
0.680 0.320 0.000
Z80.1 Family history of malignant neoplasm of trachea, bronchus and lung
0.680 0.320 0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts
0.680 0.320 0.000
I23 Certain current complications following acute myocardial infarction
0.680 0.320 0.000
Z82.6 Family history of arthritis and other diseases of the musculoskeletal system and connective tissue
0.679 0.321 0.000
I84.7 Unspecified thrombosed haemorrhoids
0.679 0.321 0.000
I45.9 Conduction disorder, unspecified
0.679 0.321 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.678 0.322 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.678 0.322 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.678 0.322 0.000
Q35-Q37 Cleft lip and cleft palate
0.678 0.322 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.678 0.322 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.678 0.322 0.000
I46 Cardiac arrest
0.677 0.323 0.000
C64-C68 Malignant neoplasms of urinary tract
0.677 0.323 0.000
C18.3 Hepatic flexure
0.677 0.323 0.000
M25 Other joint disorders, not elsewhere classified
0.675 0.325 0.000
M23.89 Other internal derangements of knee (Unspecified ligament or Unspecified meniscus)
0.674 0.325 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.674 0.326 0.000
I84.0 Internal thrombosed haemorrhoids
0.674 0.326 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.674 0.326 0.000
Z03.1 Observation for suspected malignant neoplasm
0.673 0.327 0.000
H74.8 Other specified disorders of middle ear and mastoid
0.673 0.327 0.000
D63.0 Anaemia in neoplastic disease
0.672 0.328 0.000
S83.2 Tear of meniscus, current
0.672 0.328 0.000
D75 Other diseases of blood and blood-forming organs
0.671 0.329 0.000
I82 Other venous embolism and thrombosis
0.671 0.329 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.671 0.329 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.670 0.330 0.000
Z92.8 Personal history of other medical treatment
0.669 0.330 0.000
M79.9 Soft tissue disorder, unspecified
0.669 0.331 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.669 0.331 0.000
M79.3 Panniculitis, unspecified
0.669 0.331 0.000
M79.2 Neuralgia and neuritis, unspecified
0.669 0.331 0.000
W19 Unspecified fall
0.669 0.331 0.000
D67 Hereditary factor IX deficiency
0.669 0.331 0.000
D66 Hereditary factor VIII deficiency
0.669 0.331 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.669 0.331 0.000
S01 Open wound of head
0.668 0.331 0.000
F99-F99 Unspecified mental disorder
0.668 0.332 0.000
M75.0 Adhesive capsulitis of shoulder
0.668 0.332 0.000
M70.6 Trochanteric bursitis
0.667 0.332 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.667 0.333 0.000
Z93 Artificial opening status
0.667 0.333 0.000
J15.4 Pneumonia due to other streptococci
0.666 0.334 0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis
0.666 0.334 0.000
C18.2 Ascending colon
0.666 0.334 0.000
D72 Other disorders of white blood cells
0.666 0.334 0.000
I85 Oesophageal varices
0.665 0.335 0.000
C15 Malignant neoplasm of oesophagus
0.665 0.335 0.000
I42.2 Other hypertrophic cardiomyopathy
0.665 0.335 0.000
M72 Fibroblastic disorders
0.665 0.335 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.664 0.336 0.000
Z90.5 Acquired absence of kidney
0.664 0.336 0.000
H83 Other diseases of inner ear
0.664 0.336 0.000
I45.8 Other specified conduction disorders
0.663 0.336 0.000
I45.5 Other specified heart block
0.663 0.336 0.000
I45.4 Nonspecific intraventricular block
0.663 0.336 0.000
I45.3 Trifascicular block
0.663 0.336 0.000
I45.0 Right fascicular block
0.663 0.336 0.000
M79.0 Rheumatism, unspecified
0.663 0.337 0.000
S82.60 Fracture of lateral malleolus (closed)
0.663 0.337 0.000
A46 Erysipelas
0.661 0.339 0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft
0.661 0.339 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.660 0.340 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.660 0.340 0.000
J60-J70 Lung diseases due to external agents
0.660 0.340 0.000
I34.1 Mitral (valve) prolapse
0.660 0.340 0.000
X78 Intentional self-harm by sharp object
0.659 0.340 0.000
Q23 Congenital malformations of aortic and mitral valves
0.659 0.340 0.000
Z87.3 Personal history of diseases of the musculoskeletal system and connective tissue
0.659 0.341 0.000
M79.5 Residual foreign body in soft tissue
0.659 0.341 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.658 0.342 0.000
I80.1 Phlebitis and thrombophlebitis of femoral vein
0.658 0.342 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.658 0.342 0.000
I42.9 Cardiomyopathy, unspecified
0.657 0.343 0.000
M65-M68 Disorders of synovium and tendon
0.657 0.343 0.000
M84 Disorders of continuity of bone
0.657 0.343 0.000
J18 Pneumonia, organism unspecified
0.657 0.343 0.000
S30.8 Other superficial injuries of abdomen, lower back and pelvis
0.656 0.344 0.000
Z22.5 Carrier of viral hepatitis
0.656 0.344 0.000
I60-I69 Cerebrovascular diseases
0.656 0.344 0.000
Z92.9 Personal history of medical treatment, unspecified
0.655 0.344 0.000
Z92.5 Personal history of rehabilitation measures
0.655 0.344 0.000
B18 Chronic viral hepatitis
0.655 0.345 0.000
C92.0 Acute myeloid leukaemia
0.655 0.345 0.000
T66-T78 Other and unspecified effects of external causes
0.655 0.345 0.000
M75.8 Other shoulder lesions
0.652 0.348 0.000
M75.9 Shoulder lesion, unspecified
0.652 0.348 0.000
J10 Influenza due to identified influenza virus
0.652 0.348 0.000
H73.8 Other specified disorders of tympanic membrane
0.652 0.348 0.000
Z87.7 Personal history of congenital malformations, deformations and chromosomal abnormalities
0.652 0.348 0.000
I44.6 Other and unspecified fascicular block
0.651 0.349 0.000
Z90.0 Acquired absence of part of head and neck
0.651 0.349 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.651 0.349 0.000
Z65 Problems related to other psychosocial circumstances
0.650 0.350 0.000
Z64 Problems related to certain psychosocial circumstances
0.650 0.350 0.000
Z62 Other problems related to upbringing
0.650 0.350 0.000
Z61 Problems related to negative life events in childhood
0.650 0.350 0.000
Z59 Problems related to housing and economic circumstances
0.650 0.350 0.000
Z58 Problems related to physical environment
0.650 0.350 0.000
Z56 Problems related to employment and unemployment
0.650 0.350 0.000
Z55 Problems related to education and literacy
0.650 0.350 0.000
J84.9 Interstitial pulmonary disease, unspecified
0.650 0.350 0.000
H65.4 Other chronic nonsuppurative otitis media
0.649 0.351 0.000
Z88.7 Personal history of allergy to serum and vaccine
0.648 0.352 0.000
H65.2 Chronic serous otitis media
0.647 0.352 0.000
H65.1 Other acute nonsuppurative otitis media
0.647 0.352 0.000
H65.0 Acute serous otitis media
0.647 0.352 0.000
B17 Other acute viral hepatitis
0.647 0.353 0.000
S52 Fracture of forearm
0.647 0.353 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.646 0.354 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.645 0.355 0.000
S20-S29 Injuries to the thorax
0.644 0.355 0.000
M23.83 Other internal derangements of knee (Medial collateral ligament or Other and unspecified medial meniscus)
0.644 0.356 0.000
I44.3 Other and unspecified atrioventricular block
0.644 0.356 0.000
M10.9 Gout, unspecified
0.644 0.356 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.644 0.356 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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