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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs114496068
log Bayes Factor = 15.6666
Chromosome 6   position 49,705,603  (GRCh37) Explore rs114496068 on Ensembl!
Variant rs114496068 is part of Cluster X0043

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.999 0.001 0.000
I60-I69 Cerebrovascular diseases
0.999 0.001 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.997 0.003 0.000
M20-M25 Other joint disorders
0.995 0.005 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.993 0.007 0.000
Chapter I Certain infectious and parasitic diseases
0.980 0.020 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.980 0.020 0.000
Z50 Care involving use of rehabilitation procedures
0.977 0.023 0.000
Chapter VI Diseases of the nervous system
0.976 0.024 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.973 0.027 0.000
C15-C26 Malignant neoplasms of digestive organs
0.971 0.029 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.968 0.032 0.000
C79 Secondary malignant neoplasm of other sites
0.966 0.034 0.000
I63 Cerebral infarction
0.962 0.038 0.000
B95-B98 Bacterial, viral and other infectious agents
0.962 0.038 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.959 0.041 0.000
C18 Malignant neoplasm of colon
0.958 0.042 0.000
M15-M19 Arthrosis
0.956 0.044 0.000
M20 Acquired deformities of fingers and toes
0.950 0.050 0.000
C78.7 Secondary malignant neoplasm of liver
0.948 0.052 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.944 0.056 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.944 0.056 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.942 0.058 0.000
M25 Other joint disorders, not elsewhere classified
0.940 0.060 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.939 0.061 0.000
Z13 Special screening examination for other diseases and disorders
0.935 0.065 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.932 0.068 0.000
Z37 Outcome of delivery
0.931 0.069 0.000
Chapter XX External causes of morbidity and mortality
0.930 0.070 0.000
M80-M85 Disorders of bone density and structure
0.929 0.071 0.000
Z13.9 Special screening examination, unspecified
0.926 0.074 0.000
Z51 Other medical care
0.925 0.075 0.000
M18 Arthrosis of first carpometacarpal joint
0.924 0.076 0.000
M19 Other arthrosis
0.922 0.078 0.000
C18.7 Sigmoid colon
0.922 0.078 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.917 0.083 0.000
S00-S09 Injuries to the head
0.915 0.085 0.000
I63.9 Cerebral infarction, unspecified
0.915 0.085 0.000
Z88.5 Personal history of allergy to narcotic agent
0.910 0.090 0.000
Z45 Adjustment and management of implanted device
0.905 0.095 0.000
Z37.0 Single live birth
0.904 0.096 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.902 0.098 0.000
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified
0.897 0.103 0.000
G40-G47 Episodic and paroxysmal disorders
0.892 0.108 0.000
C18.0 Caecum
0.890 0.110 0.000
D10-D36 Benign neoplasms
0.886 0.114 0.000
M45-M49 Spondylopathies
0.886 0.114 0.000
I60 Subarachnoid haemorrhage
0.883 0.117 0.000
I67 Other cerebrovascular diseases
0.883 0.117 0.000
Z50.1 Other physical therapy
0.880 0.120 0.000
Chapter VII Diseases of the eye and adnexa
0.880 0.120 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.875 0.125 0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified
0.875 0.125 0.000
C80 Malignant neoplasm without specification of site
0.869 0.131 0.000
M25.5 Pain in joint
0.866 0.134 0.000
O60-O75 Complications of labour and delivery
0.865 0.135 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.864 0.136 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.863 0.137 0.000
I30-I52 Other forms of heart disease
0.863 0.137 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.857 0.143 0.000
M81 Osteoporosis without pathological fracture
0.856 0.144 0.000
M19.9 Arthrosis, unspecified
0.855 0.145 0.000
Z51.3 Blood transfusion without reported diagnosis
0.852 0.148 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.851 0.149 0.000
M50-M54 Other dorsopathies
0.851 0.149 0.000
M20.2 Hallux rigidus
0.850 0.150 0.000
Z80 Family history of malignant neoplasm
0.849 0.151 0.000
D13 Benign neoplasm of other and ill-defined parts of digestive system
0.845 0.155 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.843 0.157 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.842 0.158 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.842 0.158 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.840 0.160 0.000
C78.2 Secondary malignant neoplasm of pleura
0.837 0.163 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.833 0.167 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.831 0.169 0.000
Z51.2 Other chemotherapy
0.829 0.171 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.829 0.171 0.000
I69 Sequelae of cerebrovascular disease
0.828 0.172 0.000
S70-S79 Injuries to the hip and thigh
0.828 0.172 0.000
Z88.0 Personal history of allergy to penicillin
0.826 0.174 0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters
0.824 0.176 0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.823 0.177 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.823 0.177 0.000
M35 Other systemic involvement of connective tissue
0.820 0.180 0.000
M47 Spondylosis
0.818 0.182 0.000
Z49 Care involving dialysis
0.818 0.182 0.000
Z51.5 Palliative care
0.818 0.182 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.814 0.186 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.813 0.187 0.000
M34 Systemic sclerosis
0.811 0.189 0.000
I67.1 Cerebral aneurysm, nonruptured
0.810 0.190 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.808 0.192 0.000
G45.9 Transient cerebral ischaemic attack, unspecified
0.808 0.192 0.000
M20.4 Other hammer toe(s) (acquired)
0.805 0.195 0.000
M81.9 Osteoporosis, unspecified
0.803 0.197 0.000
M65-M68 Disorders of synovium and tendon
0.803 0.197 0.000
Z98 Other postsurgical states
0.803 0.197 0.000
M20.1 Hallux valgus (acquired)
0.802 0.198 0.000
Z46 Fitting and adjustment of other devices
0.801 0.199 0.000
I61 Intracerebral haemorrhage
0.800 0.200 0.000
S01 Open wound of head
0.800 0.200 0.000
C78.0 Secondary malignant neoplasm of lung
0.798 0.202 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.797 0.203 0.000
S20-S29 Injuries to the thorax
0.797 0.203 0.000
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral
0.794 0.206 0.000
Z35 Supervision of high-risk pregnancy
0.794 0.206 0.000
C51-C58 Malignant neoplasms of female genital organs
0.794 0.206 0.000
Z88.6 Personal history of allergy to analgesic agent
0.794 0.206 0.000
C77.1 Intrathoracic lymph nodes
0.794 0.206 0.000
Q60-Q64 Congenital malformations of the urinary system
0.793 0.207 0.000
Z83 Family history of other specific disorders
0.793 0.207 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.792 0.208 0.000
S06 Intracranial injury
0.792 0.208 0.000
D13.1 Stomach
0.792 0.208 0.000
M19.97 Arthrosis, unspecified (Ankle and foot)
0.789 0.211 0.000
Z33 Pregnant state, incidental
0.787 0.212 0.000
A00-A09 Intestinal infectious diseases
0.787 0.213 0.000
D00-D09 In situ neoplasms
0.787 0.213 0.000
I62 Other nontraumatic intracranial haemorrhage
0.787 0.213 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.785 0.215 0.000
G35 Multiple sclerosis
0.784 0.216 0.000
Z54 Convalescence
0.784 0.216 0.000
Q80-Q89 Other congenital malformations
0.783 0.217 0.000
I35 Nonrheumatic aortic valve disorders
0.781 0.219 0.000
C25 Malignant neoplasm of pancreas
0.780 0.220 0.000
Z50.5 Speech therapy
0.779 0.221 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.778 0.222 0.000
Z45.2 Adjustment and management of vascular access device
0.778 0.222 0.000
M25.57 Pain in joint (Ankle and foot)
0.777 0.223 0.000
O26 Maternal care for other conditions predominantly related to pregnancy
0.777 0.223 0.000
D17 Benign lipomatous neoplasm
0.777 0.223 0.000
G30-G32 Other degenerative diseases of the nervous system
0.776 0.223 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.774 0.226 0.000
M05-M14 Inflammatory polyarthropathies
0.774 0.226 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.772 0.228 0.000
Chapter V Mental and behavioural disorders
0.771 0.229 0.000
C80.0 Malignant neoplasm, primary site unknown, so stated
0.770 0.230 0.000
Z88.2 Personal history of allergy to sulphonamides
0.770 0.230 0.000
G20-G26 Extrapyramidal and movement disorders
0.770 0.230 0.000
M25.7 Osteophyte
0.769 0.231 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.769 0.231 0.000
M19.0 Primary arthrosis of other joints
0.768 0.232 0.000
S40-S49 Injuries to the shoulder and upper arm
0.768 0.232 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.767 0.233 0.000
Z03 Medical observation and evaluation for suspected diseases and conditions
0.766 0.234 0.000
Y40 Systemic antibiotics
0.766 0.234 0.000
M19.1 Posttraumatic arthrosis of other joints
0.765 0.235 0.000
M21 Other acquired deformities of limbs
0.765 0.235 0.000
S90-S99 Injuries to the ankle and foot
0.764 0.236 0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.763 0.237 0.000
M31 Other necrotising vasculopathies
0.763 0.237 0.000
O72 Postpartum haemorrhage
0.762 0.238 0.000
Z90.7 Acquired absence of genital organ(s)
0.762 0.238 0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.759 0.241 0.000
I42 Cardiomyopathy
0.758 0.242 0.000
H55-H59 Other disorders of eye and adnexa
0.757 0.243 0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters
0.756 0.244 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.756 0.244 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.756 0.244 0.000
B35-B49 Mycoses
0.755 0.245 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.755 0.245 0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters
0.755 0.245 0.000
M47.8 Other spondylosis
0.754 0.246 0.000
Q23 Congenital malformations of aortic and mitral valves
0.751 0.249 0.000
M84 Disorders of continuity of bone
0.750 0.250 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.749 0.251 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.749 0.251 0.000
Z45.1 Adjustment and management of infusion pump
0.747 0.253 0.000
C77.4 Inguinal and lower limb lymph nodes
0.746 0.254 0.000
Q50-Q56 Congenital malformations of genital organs
0.745 0.254 0.000
C18.9 Colon, unspecified
0.746 0.254 0.000
I60.9 Subarachnoid haemorrhage, unspecified
0.744 0.256 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.743 0.257 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
0.743 0.257 0.000
G70-G73 Diseases of myoneural junction and muscle
0.742 0.258 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.740 0.260 0.000
Q00-Q07 Congenital malformations of the nervous system
0.740 0.260 0.000
Z88.9 Personal history of allergy to unspecified drugs, medicaments and biological substances
0.740 0.260 0.000
M24 Other specific joint derangements
0.738 0.262 0.000
Z50.0 Cardiac rehabilitation
0.738 0.262 0.000
M19.96 Arthrosis, unspecified-Lower leg
0.737 0.263 0.000
C77.2 Intra-abdominal lymph nodes
0.737 0.263 0.000
L50-L54 Urticaria and erythema
0.736 0.264 0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.735 0.265 0.000
O62 Abnormalities of forces of labour
0.733 0.267 0.000
O00-O08 Pregnancy with abortive outcome
0.732 0.268 0.000
I20-I25 Ischaemic heart diseases
0.732 0.268 0.000
M19.94 Arthrosis, unspecified (Hand)
0.731 0.269 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.731 0.269 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.730 0.270 0.000
C18.6 Descending colon
0.729 0.271 0.000
C77.0 Lymph nodes of head, face and neck
0.729 0.271 0.000
Chapter XXII Codes for special purposes
0.728 0.272 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.728 0.272 0.000
Z50.2 Alcohol rehabilitation
0.728 0.272 0.000
G40 Epilepsy
0.727 0.273 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.727 0.273 0.000
T93 Sequelae of injuries of lower limb
0.726 0.274 0.000
Z13.6 Special screening examination for cardiovascular disorders
0.725 0.274 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.725 0.275 0.000
C77.5 Intrapelvic lymph nodes
0.725 0.275 0.000
M22 Disorders of patella
0.725 0.275 0.000
Z48 Other surgical follow-up care
0.724 0.275 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.724 0.276 0.000
O36 Maternal care for other known or suspected foetal problems
0.723 0.277 0.000
B15-B19 Viral hepatitis
0.723 0.277 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.722 0.278 0.000
I73 Other peripheral vascular diseases
0.721 0.279 0.000
M25.4 Effusion of joint
0.721 0.279 0.000
Z36 Antenatal screening
0.720 0.280 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.720 0.280 0.000
M25.51 Pain in joint (Shoulder region)
0.720 0.280 0.000
Z50.8 Care involving use of rehabilitation procedures
0.719 0.281 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
M91-M94 Chondropathies
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.717 0.283 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.717 0.283 0.000
I67.2 Cerebral atherosclerosis
0.716 0.284 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.716 0.284 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.716 0.284 0.000
C79.2 Secondary malignant neoplasm of skin
0.716 0.284 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.715 0.285 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.715 0.285 0.000
Z44 Fitting and adjustment of external prosthetic device
0.715 0.285 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.715 0.285 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.714 0.286 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.714 0.286 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.713 0.287 0.000
M33 Dermatopolymyositis
0.713 0.287 0.000
M32 Systemic lupus erythematosus
0.713 0.287 0.000
M30 Polyarteritis nodosa and related conditions
0.713 0.287 0.000
M86-M90 Other osteopathies
0.713 0.287 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.713 0.287 0.000
T33-T35 Frostbite
0.712 0.288 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.712 0.288 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.712 0.288 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.712 0.288 0.000
T00-T07 Injuries involving multiple body regions
0.712 0.288 0.000
S10-S19 Injuries to the neck
0.712 0.288 0.000
Z53 Persons encountering health services for specifie procedures, not carried out
0.711 0.289 0.000
Z80.0 Family history of malignant neoplasm of digestive organs
0.711 0.289 0.000
Z13.0 Special screening examination for diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.710 0.290 0.000
M35.0 Sicca syndrome [Sjogren]
0.710 0.290 0.000
M20.5 Other deformities of toe(s) (acquired)
0.710 0.290 0.000
Z50.9 Care involving use of rehabilitation procedure, unspecified
0.709 0.290 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.709 0.291 0.000
Z41 Procedures for purposes other than remedying health state
0.709 0.291 0.000
S50-S59 Injuries to the elbow and forearm
0.708 0.292 0.000
V80-V89 Other land transport accidents
0.708 0.292 0.000
Z45.8 Adjustment and management of other implanted devices
0.708 0.292 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.708 0.292 0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.708 0.292 0.000
Z34 Supervision of normal pregnancy
0.707 0.293 0.000
O26.8 Other specified pregnancy-related conditions
0.707 0.293 0.000
H40-H42 Glaucoma
0.707 0.293 0.000
S00 Superficial injury of head
0.706 0.294 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.706 0.294 0.000
S32 Fracture of lumbar spine and pelvis
0.705 0.295 0.000
Z98.1 Arthrodesis status
0.704 0.296 0.000
B99-B99 Other infectious diseases
0.703 0.297 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.703 0.297 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.703 0.297 0.000
B65-B83 Helminthiases
0.703 0.297 0.000
B50-B64 Protozoal diseases
0.703 0.297 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.703 0.297 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.703 0.297 0.000
A80-A89 Viral infections of the central nervous system
0.703 0.297 0.000
A75-A79 Rickettsioses
0.703 0.297 0.000
A70-A74 Other diseases caused by chlamydiae
0.703 0.297 0.000
A65-A69 Other spirochaetal diseases
0.703 0.297 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.703 0.297 0.000
A20-A28 Certain zoonotic bacterial diseases
0.703 0.297 0.000
A15-A19 Tuberculosis
0.703 0.297 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.702 0.297 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.702 0.297 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.702 0.297 0.000
O80-O84 Delivery
0.701 0.299 0.000
Z52 Donors of organs and tissues
0.701 0.299 0.000
Z50.6 Orthoptic training
0.701 0.299 0.000
Z50.4 Psychotherapy, not elsewhere classified
0.701 0.299 0.000
Z50.3 Drug rehabilitation
0.701 0.299 0.000
Z80.3 Family history of malignant neoplasm of breast
0.701 0.299 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.700 0.300 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.699 0.300 0.000
O85-O92 Complications predominantly related to the puerperium
0.698 0.302 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.697 0.302 0.000
I45 Other conduction disorders
0.697 0.303 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.697 0.303 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.696 0.304 0.000
C21 Malignant neoplasm of anus and anal canal
0.696 0.304 0.000
C17 Malignant neoplasm of small intestine
0.696 0.304 0.000
C23 Malignant neoplasm of gallbladder
0.696 0.304 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.696 0.304 0.000
T79-T79 Certain early complications of trauma
0.695 0.304 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.695 0.305 0.000
M81.99 Osteoporosis, unspecified (Site unspecified)
0.695 0.305 0.000
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters
0.694 0.305 0.000
Z38 Liveborn infants according to place of birth
0.694 0.306 0.000
Z32 Pregnancy examination and test
0.694 0.306 0.000
Z31 Procreative management
0.694 0.306 0.000
M70-M79 Other soft tissue disorders
0.693 0.307 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.693 0.307 0.000
C79.6 Secondary malignant neoplasm of ovary
0.692 0.308 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.692 0.308 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.692 0.308 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.692 0.308 0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis
0.692 0.308 0.000
Chapter VIII Diseases of the ear and mastoid process
0.692 0.308 0.000
D32 Benign neoplasm of meninges
0.691 0.309 0.000
I63.8 Other cerebral infarction
0.690 0.310 0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.690 0.310 0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.690 0.310 0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.690 0.310 0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.690 0.310 0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.690 0.310 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.690 0.310 0.000
L90 Atrophic disorders of skin
0.690 0.310 0.000
D13.0 Oesophagus
0.690 0.310 0.000
Z02 Examination and encounter for administrative purposes
0.689 0.311 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.689 0.311 0.000
H53-H54 Visual disturbances and blindness
0.688 0.312 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.688 0.312 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.687 0.312 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.687 0.312 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.687 0.312 0.000
Q35-Q37 Cleft lip and cleft palate
0.687 0.312 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.687 0.312 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.687 0.312 0.000
C18.8 Overlapping lesion of colon
0.687 0.313 0.000
C18.5 Splenic flexure
0.687 0.313 0.000
C18.4 Transverse colon
0.687 0.313 0.000
C18.3 Hepatic flexure
0.687 0.313 0.000
C18.1 Appendix
0.687 0.313 0.000
M54 Dorsalgia
0.687 0.313 0.000
Q23.1 Congenital insufficiency of aortic valve
0.686 0.314 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.685 0.315 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.685 0.315 0.000
S02 Fracture of skull and facial bones
0.685 0.315 0.000
M15 Polyarthrosis
0.685 0.315 0.000
S70 Superficial injury of hip and thigh
0.685 0.315 0.000
Z98.8 Other specified postsurgical states
0.685 0.315 0.000
O71 Other obstetric trauma
0.684 0.316 0.000
Z00.0 General medical examination
0.683 0.316 0.000
I84 Haemorrhoids
0.683 0.317 0.000
Z49.0 Preparatory care for dialysis
0.682 0.317 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.682 0.318 0.000
M20.3 Other deformity of hallux (acquired)
0.681 0.319 0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters
0.680 0.320 0.000
Z83.5 Family history of eye and ear disorders
0.680 0.320 0.000
M34.9 Systemic sclerosis, unspecified
0.679 0.321 0.000
L91 Hypertrophic disorders of skin
0.679 0.321 0.000
M25.78 Osteophyte (Other)
0.679 0.321 0.000
M18.1 Other primary arthrosis of first carpometacarpal joint
0.678 0.322 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.678 0.322 0.000
M25.50 Pain in joint (Multiple sites)
0.677 0.322 0.000
Z10 Routine general health check-up of defined subpopulation
0.676 0.323 0.000
T98 Sequelae of other and unspecified effects of external causes
0.677 0.323 0.000
Z89 Acquired absence of limb
0.676 0.324 0.000
Z84 Family history of other conditions
0.676 0.324 0.000
Z81 Family history of mental and behavioural disorders
0.676 0.324 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.675 0.325 0.000
D17.2 Benign lipomatous neoplasm of skin and subcutaneous tissue of limbs
0.674 0.326 0.000
M25.9 Joint disorder, unspecified
0.674 0.326 0.000
M25.8 Other specified joint disorders
0.674 0.326 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.674 0.326 0.000
M25.3 Other instability of joint
0.674 0.326 0.000
M25.2 Flail joint
0.674 0.326 0.000
M25.1 Fistula of joint
0.674 0.326 0.000
M25.0 Haemarthrosis
0.674 0.326 0.000
O72.1 Other immediate postpartum haemorrhage
0.674 0.326 0.000
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters
0.673 0.326 0.000
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters
0.673 0.326 0.000
B96.0 Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified to other chapters
0.673 0.326 0.000
M50 Cervical disk disorders
0.673 0.326 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.672 0.328 0.000
Z87 Personal history of other diseases and conditions
0.672 0.328 0.000
G90-G99 Other disorders of the nervous system
0.672 0.328 0.000
M65 Synovitis and tenosynovitis
0.671 0.329 0.000
I20 Angina pectoris
0.671 0.329 0.000
T66-T78 Other and unspecified effects of external causes
0.671 0.329 0.000
Z13.8 Special screening examination for other specified diseases and disorders
0.670 0.330 0.000
Z13.7 Special screening examination for congenital malformations, deformations and chromosomal abnormalities
0.670 0.330 0.000
Z13.5 Special screening examination for eye and ear disorders
0.670 0.330 0.000
Z13.4 Special screening examination for certain developmental disorders in childhood
0.670 0.330 0.000
Z13.3 Special screening examination for mental and behavioural disorders
0.670 0.330 0.000
Z13.2 Special screening examination for nutritional disorders
0.670 0.330 0.000
Z13.1 Special screening examination for diabetes mellitus
0.670 0.330 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.670 0.330 0.000
M35.7 Hypermobility syndrome
0.670 0.330 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.670 0.330 0.000
Z80.1 Family history of malignant neoplasm of trachea, bronchus and lung
0.669 0.330 0.000
M85 Other disorders of bone density and structure
0.668 0.332 0.000
Z88.7 Personal history of allergy to serum and vaccine
0.668 0.332 0.000
Z47 Other orthopaedic follow-up care
0.668 0.332 0.000
Z37.9 Outcome of delivery unspecified
0.667 0.333 0.000
Z37.7 Other multiple births, all stillborn
0.667 0.333 0.000
Z37.6 Other multiple births, some liveborn
0.667 0.333 0.000
Z37.5 Other multiple births, all liveborn
0.667 0.333 0.000
Z37.4 Twins, both stillborn
0.667 0.333 0.000
Z37.3 Twins, one liveborn and one stillborn
0.667 0.333 0.000
Z37.1 Single stillbirth
0.667 0.333 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.667 0.333 0.000
Z37.2 Twins, both liveborn
0.667 0.333 0.000
M19.07 Primary arthrosis of other joints (Ankle and foot)
0.667 0.333 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.667 0.333 0.000
Y35-Y36 Legal intervention and operations of war
0.667 0.333 0.000
Y10-Y34 Event of undetermined intent
0.667 0.333 0.000
Y00-Y09 Assault
0.667 0.333 0.000
X85-X99 Assault
0.667 0.333 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.667 0.333 0.000
X50-X57 Overexertion, travel and privation
0.667 0.333 0.000
X30-X39 Exposure to forces of nature
0.667 0.333 0.000
X20-X29 Contact with venomous animals and plants
0.667 0.333 0.000
X10-X19 Contact with heat and hot substances
0.667 0.333 0.000
X00-X09 Exposure to smoke, fire and flames
0.667 0.333 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.667 0.333 0.000
W75-W84 Other accidental threats to breathing
0.667 0.333 0.000
W65-W74 Accidental drowning and submersion
0.667 0.333 0.000
W50-W64 Exposure to animate mechanical forces
0.667 0.333 0.000
V98-V99 Other and unspecified transport accidents
0.667 0.333 0.000
V95-V97 Air and space transport accidents
0.667 0.333 0.000
V90-V94 Water transport accidents
0.667 0.333 0.000
V70-V79 Bus occupant injured in transport accident
0.667 0.333 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.667 0.333 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.667 0.333 0.000
V40-V49 Car occupant injured in transport accident
0.667 0.333 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.667 0.333 0.000
V01-V09 Pedestrian injured in transport accident
0.667 0.333 0.000
M83 Adult osteomalacia
0.666 0.334 0.000
M82 Osteoporosis in diseases classified elsewhere
0.666 0.334 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.665 0.335 0.000
Z03.8 Observation for other suspected diseases and conditions
0.664 0.336 0.000
Z51.4 Preparatory care for treatment, not elsewhere classified
0.664 0.336 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.663 0.337 0.000
D17.0 Benign lipomatous neoplasm of skin and subcutaneous tissue of head, face and neck
0.663 0.337 0.000
Z51.9 Medical care, unspecified
0.663 0.337 0.000
Z51.6 Desensitisation to allergens
0.663 0.337 0.000
M18.5 Other secondary arthrosis of first carpometacarpal joint
0.662 0.338 0.000
M18.4 Other secondary arthrosis of first carpometacarpal joints, bilateral
0.662 0.338 0.000
M18.3 Other posttraumatic arthrosis of first carpometacarpal joint
0.662 0.338 0.000
M18.2 Posttraumatic arthrosis of first carpometacarpal joints, bilateral
0.662 0.338 0.000
S06.5 Traumatic subdural haemorrhage
0.662 0.338 0.000
L53 Other erythematous conditions
0.662 0.338 0.000
D60-D64 Aplastic and other anaemias
0.661 0.339 0.000
M19.8 Other specified arthrosis
0.661 0.339 0.000
M19.2 Other secondary arthrosis
0.661 0.339 0.000
I86 Varicose veins of other sites
0.661 0.339 0.000
Z46.8 Fitting and adjustment of other specified devices
0.661 0.339 0.000
A30-A49 Other bacterial diseases
0.661 0.339 0.000
S01.8 Open wound of other parts of head
0.660 0.340 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.660 0.340 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.660 0.340 0.000
D34 Benign neoplasm of thyroid gland
0.660 0.340 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.660 0.340 0.000
M80 Osteoporosis with pathological fracture
0.659 0.341 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.659 0.341 0.000
S80-S89 Injuries to the knee and lower leg
0.659 0.341 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.659 0.341 0.000
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)
0.658 0.341 0.000
W00-W19 Falls
0.658 0.342 0.000
Z43 Attention to artificial openings
0.658 0.342 0.000
I61.9 Intracerebral haemorrhage, unspecified
0.658 0.342 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.658 0.342 0.000
Z80.5 Family history of malignant neoplasm of urinary tract
0.657 0.342 0.000
I73.0 Raynaud's syndrome
0.657 0.343 0.000
C77.8 Lymph nodes of multiple regions
0.657 0.343 0.000
I35.0 Aortic (valve) stenosis
0.657 0.343 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.656 0.344 0.000
S08 Traumatic amputation of part of head
0.656 0.344 0.000
S07 Crushing injury of head
0.656 0.344 0.000
S05 Injury of eye and orbit
0.656 0.344 0.000
S04 Injury of cranial nerves
0.656 0.344 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.656 0.344 0.000
M20.6 Acquired deformity of toe(s), unspecified
0.656 0.344 0.000
X60-X84 Intentional self-harm
0.655 0.345 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.655 0.345 0.000
F30-F39 Mood [affective] disorders
0.654 0.346 0.000
Z03.4 Observation for suspected myocardial infarction
0.654 0.346 0.000
D33 Benign neoplasm of brain and other parts of central nervous system
0.653 0.347 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.653 0.347 0.000
M19.17 Post-traumatic arthrosis of other joints (Ankle and foot)
0.653 0.347 0.000
M20.0 Deformity of finger(s)
0.652 0.348 0.000
D03 Melanoma in situ
0.650 0.350 0.000
V20-V29 Motorcycle rider injured in transport accident
0.650 0.350 0.000
C16 Malignant neoplasm of stomach
0.650 0.350 0.000
Z45.9 Adjustment and management of unspecified implanted device
0.649 0.351 0.000
Z45.3 Adjustment and management of implanted hearing device
0.649 0.351 0.000
Q28 Other congenital malformations of circulatory system
0.649 0.351 0.000
Z22 Carrier of infectious disease
0.648 0.351 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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