TreeWAS – Variant ID: rs114506037

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status	1.000	0.000
Chapter XXI Factors influencing health status and contact with health services	1.000	0.000
# Top node	1.000	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	1.000	0.000
Chapter IX Diseases of the circulatory system	0.999	0.001
Z86 Personal history of certain other diseases	0.999	0.001
I20-I25 Ischaemic heart diseases	0.998	0.002
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.998	0.002
Z95 Presence of cardiac and vascular implants and grafts	0.997	0.003
Z82 Family history of certain disabilities and chronic diseases leading to disablement	0.996	0.004
Z92 Personal history of medical treatment	0.995	0.005
Z86.6 Personal history of diseases of the nervous system and sense organs	0.994	0.006
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system	0.994	0.006
I25 Chronic ischaemic heart disease	0.988	0.012
Z92.2 Personal history of long-term (current) use of other medicaments	0.987	0.013
Z86.7 Personal history of diseases of the circulatory system	0.987	0.013
M45-M49 Spondylopathies	0.985	0.015
Z98 Other postsurgical states	0.982	0.018
S80-S89 Injuries to the knee and lower leg	0.974	0.026
Z92.1 Personal history of long-term (current) use of anticoagulants	0.971	0.029
S60-S69 Injuries to the wrist and hand	0.966	0.034
M47 Spondylosis	0.964	0.036
I20 Angina pectoris	0.963	0.037
Z95.8 Presence of other cardiac and vascular implants and grafts	0.961	0.039
I25.9 Chronic ischaemic heart disease, unspecified	0.960	0.040
Z00-Z13 Persons encountering health services for examination and investigation	0.955	0.045
Z90 Acquired absence of organs, not elsewhere classified	0.954	0.046
Chapter VII Diseases of the eye and adnexa	0.953	0.047
Chapter II Neoplasms	0.951	0.049
Z95.4 Presence of other heart-valve replacement	0.949	0.051
Z08 Follow-up examination after treatment for malignant neoplasm	0.948	0.052
I20.9 Angina pectoris, unspecified	0.944	0.056
M47.8 Other spondylosis	0.935	0.065
Chapter V Mental and behavioural disorders	0.934	0.066
Z98.0 Intestinal bypass and anastomosis status	0.934	0.066
Chapter XII Diseases of the skin and subcutaneous tissue	0.930	0.070
S82 Fracture of lower leg, including ankle	0.924	0.076
M20-M25 Other joint disorders	0.922	0.078
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.921	0.079
Z95.5 Presence of coronary angioplasty implant and graft	0.920	0.080
I60-I69 Cerebrovascular diseases	0.915	0.085
Z98.8 Other specified postsurgical states	0.909	0.091
I25.2 Old myocardial infarction	0.901	0.099
M25 Other joint disorders, not elsewhere classified	0.891	0.109
Z90.4 Acquired absence of other parts of digestive tract	0.891	0.109
Z08.0 Follow-up examination after surgery for malignant neoplasm	0.888	0.112
S82.8 Fractures of other parts of lower leg	0.888	0.112
H30-H36 Disorders of choroid and retina	0.883	0.117
Chapter XV Pregnancy, childbirth and the puerperium	0.881	0.119
M40-M43 Deforming dorsopathies	0.880	0.120
C15-C26 Malignant neoplasms of digestive organs	0.862	0.138
S82.80 Fractures of other parts of lower leg (closed)	0.861	0.139
Z08.9 Follow-up examination after unspecified treatment for malignant neoplasm	0.856	0.144
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.855	0.145
Z86.5 Personal history of other mental and behavioural disorders	0.854	0.146
Z95.2 Presence of prosthetic heart valve	0.853	0.147
Z70-Z76 Persons encountering health services in other circumstances	0.850	0.149
Z08.7 Follow-up examination after combined treatment for malignant neoplasm	0.850	0.150
S64 Injury of nerves at wrist and hand level	0.850	0.150
M25.5 Pain in joint	0.846	0.154
T36-T50 Poisoning by drugs, medicaments and biological substances	0.842	0.158
C64-C68 Malignant neoplasms of urinary tract	0.840	0.160
S81 Open wound of lower leg	0.838	0.162
H36 Retinal disorders in diseases classified elsewhere	0.838	0.162
I24 Other acute ischaemic heart diseases	0.837	0.163
T85 Complications of other internal prosthetic devices, implants and grafts	0.835	0.165
M47.82 Other spondylosis (Cervical region)	0.835	0.165
S90-S99 Injuries to the ankle and foot	0.833	0.167
Z89 Acquired absence of limb	0.832	0.168
M47.9 Spondylosis, unspecified	0.826	0.174
Z90.7 Acquired absence of genital organ(s)	0.818	0.182
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.817	0.183
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.816	0.184
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.816	0.184
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.813	0.187
F30-F39 Mood [affective] disorders	0.811	0.189
I70-I79 Diseases of arteries, arterioles and capillaries	0.810	0.190
M46 Other inflammatory spondylopathies	0.810	0.190
M45 Ankylosing spondylitis	0.810	0.190
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.806	0.194
H36.0 Diabetic retinopathy	0.805	0.195
M70-M79 Other soft tissue disorders	0.805	0.195
M47.86 Other spondylosis (Lumbar region)	0.804	0.196
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.803	0.197
C18 Malignant neoplasm of colon	0.797	0.203
S00-S09 Injuries to the head	0.797	0.203
M47.87 Other spondylosis (Lumbosacral region)	0.796	0.204
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.796	0.204
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis	0.795	0.205
S66 Injury of muscle and tendon at wrist and hand level	0.793	0.207
C67 Malignant neoplasm of bladder	0.789	0.211
C16 Malignant neoplasm of stomach	0.786	0.214
C34 Malignant neoplasm of bronchus and lung	0.786	0.214
I30-I52 Other forms of heart disease	0.786	0.214
I63 Cerebral infarction	0.783	0.217
L80-L99 Other disorders of the skin and subcutaneous tissue	0.780	0.220
S40-S49 Injuries to the shoulder and upper arm	0.778	0.222
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.778	0.222
Z90.8 Acquired absence of other organs	0.777	0.223
L00-L08 Infections of the skin and subcutaneous tissue	0.771	0.228
S60 Superficial injury of wrist and hand	0.771	0.229
S61 Open wound of wrist and hand	0.770	0.230
Chapter X Diseases of the respiratory system	0.769	0.231
D37-D48 Neoplasms of uncertain or unknown behaviour	0.768	0.232
S80 Superficial injury of lower leg	0.766	0.234
S64.4 Injury of digital nerve of other finger	0.766	0.234
Z86.1 Personal history of infectious and parasitic diseases	0.763	0.237
M43 Other deforming dorsopathies	0.761	0.239
I25.1 Atherosclerotic heart disease	0.759	0.241
Z85 Personal history of malignant neoplasm	0.758	0.242
I69 Sequelae of cerebrovascular disease	0.758	0.242
Z90.6 Acquired absence of other parts of urinary tract	0.756	0.244
T88 Other complications of surgical and medical care, not elsewhere classified	0.756	0.244
S69 Other and unspecified injuries of wrist and hand	0.756	0.244
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.755	0.245
H53-H54 Visual disturbances and blindness	0.754	0.246
M25.7 Osteophyte	0.754	0.246
Z40-Z54 Persons encountering health services for specific procedures and health care	0.754	0.246
Z95.9 Presence of cardiac and vascular implant and graft, unspecified	0.752	0.248
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.751	0.248
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts	0.750	0.250
M23 Internal derangement of knee	0.749	0.251
F40-F48 Neurotic, stress-related and somatoform disorders	0.748	0.251
Z92.0 Personal history of contraception	0.748	0.252
Z11 Special screening examination for infectious and parasitic diseases	0.745	0.254
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.745	0.255
I24.9 Acute ischaemic heart disease, unspecified	0.744	0.256
I20.1 Angina pectoris with documented spasm	0.741	0.259
I22 Subsequent myocardial infarction	0.738	0.262
Z08.8 Follow-up examination after other treatment for malignant neoplasm	0.738	0.262
S82.5 Fracture of medial malleolus	0.738	0.262
S20-S29 Injuries to the thorax	0.738	0.262
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.737	0.263
Z90.1 Acquired absence of breast(s)	0.736	0.264
O94-O99 Other obstetric conditions, not elsewhere classified	0.734	0.266
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.733	0.267
M25.59 Pain in joint (Site unspecified)	0.732	0.268
M24 Other specific joint derangements	0.731	0.269
M80-M85 Disorders of bone density and structure	0.730	0.269
F80-F89 Disorders of psychological development	0.730	0.270
M25.57 Pain in joint (Ankle and foot)	0.728	0.272
S62 Fracture at wrist and hand level	0.728	0.272
H10-H13 Disorders of conjunctiva	0.728	0.272
Z30-Z39 Persons encountering health services in circumstances related to reproduction	0.726	0.274
S70-S79 Injuries to the hip and thigh	0.725	0.275
C51-C58 Malignant neoplasms of female genital organs	0.723	0.277
I25.8 Other forms of chronic ischaemic heart disease	0.722	0.278
I05-I09 Chronic rheumatic heart diseases	0.721	0.279
Z72 Problems related to lifestyle	0.720	0.280
T66-T78 Other and unspecified effects of external causes	0.720	0.280
Z00 General examination and investigation of persons without complaint or reported diagnosis	0.720	0.280
M65-M68 Disorders of synovium and tendon	0.719	0.281
Z99 Dependence on enabling machines and devices, not elsewhere classified	0.719	0.281
T15-T19 Effects of foreign body entering through natural orifice	0.718	0.282
L40-L45 Papulosquamous disorders	0.718	0.282
M47.80 Other spondylosis (Multiple sites in spine)	0.717	0.283
Z97 Presence of other devices	0.717	0.283
Z84 Family history of other conditions	0.717	0.283
Z81 Family history of mental and behavioural disorders	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.717	0.283
T79-T79 Certain early complications of trauma	0.717	0.283
T33-T35 Frostbite	0.717	0.283
T26-T28 Burns and corrosions confined to eye and internal organs	0.717	0.283
T20-T25 Burns and corrosions of external body surface, specified by site	0.717	0.283
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.717	0.283
T00-T07 Injuries involving multiple body regions	0.717	0.283
S10-S19 Injuries to the neck	0.717	0.283
I00-I02 Acute rheumatic fever	0.716	0.283
H35 Other retinal disorders	0.716	0.284
I23 Certain current complications following acute myocardial infarction	0.716	0.284
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.715	0.285
M91-M94 Chondropathies	0.715	0.285
M60-M63 Disorders of muscles	0.715	0.285
M00-M03 Infectious arthropathies	0.715	0.285
Chapter XXII Codes for special purposes	0.715	0.285
Z95.3 Presence of xenogenic heart valve	0.715	0.285
I34 Nonrheumatic mitral valve disorders	0.715	0.285
Z82.8 Family history of other disabilities and chronic diseases leading to disablement, not elsewhere classified	0.714	0.286
Z82.7 Family history of congenital malformations, deformations and chromosomal abnormalities	0.714	0.286
Z82.6 Family history of arthritis and other diseases of the musculoskeletal system and connective tissue	0.714	0.286
Z82.5 Family history of asthma and other chronic lower respiratory diseases	0.714	0.286
Z82.2 Family history of deafness and hearing loss	0.714	0.286
Z82.1 Family history of blindness and visual loss	0.714	0.286
Z82.0 Family history of epilepsy and other diseases of the nervous system	0.714	0.286
Z92.9 Personal history of medical treatment, unspecified	0.713	0.286
Z92.8 Personal history of other medical treatment	0.713	0.286
Z92.5 Personal history of rehabilitation measures	0.713	0.286
L20-L30 Dermatitis and eczema	0.713	0.287
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.713	0.287
Z94 Transplanted organ and tissue status	0.712	0.288
S91 Open wound of ankle and foot	0.712	0.288
S68 Traumatic amputation of wrist and hand	0.711	0.288
I49 Other cardiac arrhythmias	0.709	0.291
I25.6 Silent myocardial ischaemia	0.709	0.291
I25.5 Ischaemic cardiomyopathy	0.709	0.291
I25.4 Coronary artery aneurysm	0.709	0.291
I25.3 Aneurysm of heart	0.709	0.291
I25.0 Atherosclerotic cardiovascular disease, so described	0.709	0.291
M49 Spondylopathies in diseases classified elsewhere	0.706	0.293
M25.9 Joint disorder, unspecified	0.706	0.294
Chapter VI Diseases of the nervous system	0.704	0.296
Z98.2 Presence of cerebrospinal fluid drainage device	0.704	0.296
C43-C44 Melanoma and other malignant neoplasms of skin	0.704	0.296
Z98.1 Arthrodesis status	0.702	0.298
M41 Scoliosis	0.702	0.298
H52 Disorders of refraction and accommodation	0.701	0.299
F33 Recurrent depressive disorder	0.700	0.300
Z93 Artificial opening status	0.700	0.300
Z83 Family history of other specific disorders	0.699	0.300
L90 Atrophic disorders of skin	0.699	0.301
I64 Stroke, not specified as haemorrhage or infarction	0.699	0.301
Z01.6 Radiological examination, not elsewhere classified	0.699	0.301
S89 Other and unspecified injuries of lower leg	0.698	0.302
S88 Traumatic amputation of lower leg	0.698	0.302
S87 Crushing injury of lower leg	0.698	0.302
S86 Injury of muscle and tendon at lower leg level	0.698	0.302
S85 Injury of blood vessels at lower leg level	0.698	0.302
S84 Injury of nerves at lower leg level	0.698	0.302
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.698	0.302
J30-J39 Other diseases of upper respiratory tract	0.698	0.302
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.697	0.303
L03 Cellulitis	0.697	0.303
Z03 Medical observation and evaluation for suspected diseases and conditions	0.695	0.305
M25.54 Pain in joint (Hand)	0.695	0.305
C18.0 Caecum	0.695	0.305
F32 Depressive episode	0.694	0.306
M47.99 Spondylosis, unspecified (Site unspecified)	0.693	0.307
S67 Crushing injury of wrist and hand	0.693	0.307
S65 Injury of blood vessels at wrist and hand level	0.693	0.307
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.693	0.307
L60-L75 Disorders of skin appendages	0.692	0.308
M50-M54 Other dorsopathies	0.692	0.308
M47.2 Other spondylosis with radiculopathy	0.691	0.309
M47.1 Other spondylosis with myelopathy	0.691	0.309
M47.0 Anterior spinal and vertebral artery compression syndromes	0.691	0.309
M86-M90 Other osteopathies	0.691	0.309
Z72.0 Tobacco use	0.691	0.309
H04 Disorders of lachrymal system	0.690	0.310
L50-L54 Urticaria and erythema	0.690	0.310
Z08.2 Follow-up examination after chemotherapy for malignant neoplasm	0.689	0.311
M48 Other spondylopathies	0.688	0.312
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.687	0.312
F29 Unspecified nonorganic psychosis	0.686	0.314
Z90.3 Acquired absence of part of stomach	0.686	0.314
J90-J94 Other diseases of pleura	0.686	0.314
S81.8 Open wound of other parts of lower leg	0.686	0.314
S81.9 Open wound of lower leg, part unspecified	0.686	0.314
T51 Toxic effect of alcohol	0.685	0.315
Z89.5 Acquired absence of leg at or below knee	0.685	0.315
Z10 Routine general health check-up of defined subpopulation	0.685	0.315
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.684	0.316
Z90.0 Acquired absence of part of head and neck	0.684	0.316
I62 Other nontraumatic intracranial haemorrhage	0.684	0.316
M46.9 Inflammatory spondylopathy, unspecified	0.684	0.316
M45.X9 Ankylosing spondylitis (Site unspecified)	0.684	0.316
H55-H59 Other disorders of eye and adnexa	0.683	0.317
H46-H48 Disorders of optic nerve and visual pathways	0.683	0.317
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts	0.683	0.317
S82.2 Fracture of shaft of tibia	0.683	0.317
S82.0 Fracture of patella	0.682	0.318
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.682	0.318
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.682	0.318
C40-C41 Malignant neoplasms of bone and articular cartilage	0.682	0.318
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.682	0.318
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified	0.680	0.319
L03.3 Cellulitis of trunk	0.680	0.320
I60 Subarachnoid haemorrhage	0.680	0.320
Z86.2 Personal history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.679	0.320
Z08.1 Follow-up examination after radiotherapy for malignant neoplasm	0.679	0.321
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.679	0.321
S82.6 Fracture of lateral malleolus	0.678	0.322
C16.9 Stomach, unspecified	0.678	0.322
H40-H42 Glaucoma	0.678	0.322
M79 Other soft tissue disorders, not elsewhere classified	0.677	0.323
C67.2 Lateral wall of bladder	0.677	0.323
M43.1 Spondylolisthesis	0.677	0.323
C34.1 Upper lobe, bronchus or lung	0.676	0.324
C16.0 Cardia	0.675	0.325
Z42 Follow-up care involving plastic surgery	0.673	0.327
M25.78 Osteophyte (Other)	0.672	0.328
I35 Nonrheumatic aortic valve disorders	0.671	0.329
O60-O75 Complications of labour and delivery	0.671	0.329
M47.89 Other spondylosis (Site unspecified)	0.670	0.330
M47.88 Other spondylosis (Sacral and sacrococcygeal region)	0.670	0.330
M47.85 Other spondylosis (Thoracolumbar region)	0.670	0.330
M47.84 Other spondylosis (Thoracic region)	0.670	0.330
M47.83 Other spondylosis (Cervicothoracic region)	0.670	0.330
M47.81 Other spondylosis (Occipito-atlanto-axial region)	0.670	0.330
F99-F99 Unspecified mental disorder	0.670	0.330
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.670	0.330
F70-F79 Mental retardation	0.670	0.330
F60-F69 Disorders of adult personality and behaviour	0.670	0.330
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.670	0.330
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level	0.670	0.330
Z74 Problems related to care-provider dependency	0.669	0.330
C67.9 Bladder, unspecified	0.669	0.331
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.669	0.331
L10-L14 Bullous disorders	0.667	0.333
M31 Other necrotising vasculopathies	0.665	0.335
M25.51 Pain in joint (Shoulder region)	0.664	0.336
O20-O29 Other maternal disorders predominantly related to pregnancy	0.664	0.336
S82.9 Fracture of lower leg, part unspecified	0.663	0.337
S82.7 Multiple fractures of lower leg	0.663	0.337
S82.4 Fracture of fibula alone	0.663	0.337
D60-D64 Aplastic and other anaemias	0.662	0.338
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.661	0.338
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.661	0.339
M34 Systemic sclerosis	0.661	0.339
M33 Dermatopolymyositis	0.661	0.339
M32 Systemic lupus erythematosus	0.661	0.339
M30 Polyarteritis nodosa and related conditions	0.661	0.339
M21 Other acquired deformities of limbs	0.661	0.339
M05-M14 Inflammatory polyarthropathies	0.660	0.340
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.660	0.340
T87 Complications peculiar to reattachment and amputation	0.660	0.340
T86 Failure and rejection of transplanted organs and tissues	0.660	0.340
T80 Complications following infusion, transfusion and therapeutic injection	0.660	0.340
Chapter VIII Diseases of the ear and mastoid process	0.660	0.340
Z75 Problems related to medical facilities and other health care	0.658	0.341
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.657	0.343
I68 Cerebrovascular disorders in diseases classified elsewhere	0.656	0.344
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.656	0.344
F00-F09 Organic, including symptomatic, mental disorders	0.655	0.345
I77 Other disorders of arteries and arterioles	0.655	0.345
Z86.3 Personal history of endocrine, nutritional and metabolic diseases	0.653	0.347
H54 Blindness and low vision	0.652	0.348
L90.5 Scar conditions and fibrosis of skin	0.652	0.348
I61 Intracerebral haemorrhage	0.650	0.349
I51 Complications and ill-defined descriptions of heart disease	0.650	0.350
I34.0 Mitral (valve) insufficiency	0.650	0.350
C67.1 Dome of bladder	0.650	0.350
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.649	0.351
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts	0.649	0.351
M23.8 Other internal derangements of knee	0.647	0.353
D10-D36 Benign neoplasms	0.647	0.353
T85.2 Mechanical complication of intraocular lens	0.646	0.353
S61.8 Open wound of other parts of wrist and hand	0.645	0.355
Z43 Attention to artificial openings	0.645	0.355
M35 Other systemic involvement of connective tissue	0.644	0.356
Z60 Problems related to social environment	0.644	0.356
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.642	0.358
C18.6 Descending colon	0.641	0.359
I74 Arterial embolism and thrombosis	0.641	0.359
M15-M19 Arthrosis	0.640	0.360
Z89.4 Acquired absence of foot and ankle	0.640	0.360
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.640	0.360
M25.8 Other specified joint disorders	0.639	0.361
M25.6 Stiffness of joint, not elsewhere classified	0.639	0.361
M25.3 Other instability of joint	0.639	0.361
M25.2 Flail joint	0.639	0.361
M25.1 Fistula of joint	0.639	0.361
M25.0 Haemarthrosis	0.639	0.361
I95-I99 Other and unspecified disorders of the circulatory system	0.638	0.362
F41 Other anxiety disorders	0.638	0.362
C34.3 Lower lobe, bronchus or lung	0.638	0.362
O42 Premature rupture of membranes	0.638	0.362
I71 Aortic aneurysm and dissection	0.638	0.362
O46 Antepartum haemorrhage, not elsewhere classified	0.637	0.363
C34.9 Bronchus or lung, unspecified	0.637	0.363
S82.86 Maisonneuve's fracture	0.636	0.364
S82.81 Fractures of other parts of lower leg (open)	0.636	0.364
H34 Retinal vascular occlusions	0.636	0.364
L91 Hypertrophic disorders of skin	0.636	0.364
H02 Other disorders of eyelid	0.636	0.364
H32 Chorioretinal disorders in diseases classified elsewhere	0.633	0.367
H31 Other disorders of choroid	0.633	0.367
H30 Chorioretinal inflammation	0.633	0.367
S00 Superficial injury of head	0.633	0.367
C18.5 Splenic flexure	0.633	0.367
O85-O92 Complications predominantly related to the puerperium	0.631	0.368
Z57 Occupational exposure to risk-factors	0.631	0.369
M42 Spinal osteochondrosis	0.631	0.369
M40 Kyphosis and lordosis	0.631	0.369
M47.92 Spondylosis, unspecified (Cervical region)	0.630	0.370
Z85.3 Personal history of malignant neoplasm of breast	0.629	0.371
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.629	0.371
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.628	0.372
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.627	0.373
S91.3 Open wound of other parts of foot	0.626	0.374
S80.8 Other superficial injuries of lower leg	0.626	0.374
I20.8 Other forms of angina pectoris	0.624	0.376
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.624	0.376
C15 Malignant neoplasm of oesophagus	0.624	0.376
S50-S59 Injuries to the elbow and forearm	0.624	0.376
T88.4 Failed or difficult intubation	0.623	0.376
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.622	0.378
H43-H45 Disorders of vitreous body and globe	0.622	0.378
M47.96 Spondylosis, unspecified (Lumbar region)	0.619	0.381
O47 False labour	0.619	0.381
J34 Other disorders of nose and nasal sinuses	0.618	0.382
C26 Malignant neoplasm of other and ill-defined digestive organs	0.618	0.382
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.618	0.382
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.618	0.382
C21 Malignant neoplasm of anus and anal canal	0.618	0.382
C17 Malignant neoplasm of small intestine	0.618	0.382
C23 Malignant neoplasm of gallbladder	0.618	0.382
H50 Other strabismus	0.617	0.382
Z48 Other surgical follow-up care	0.617	0.383
I20.0 Unstable angina	0.617	0.383
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.617	0.383
D00-D09 In situ neoplasms	0.615	0.384
C18.4 Transverse colon	0.615	0.385
C97 Malignant neoplasms of independent (primary) multiple sites	0.615	0.385
O48 Prolonged pregnancy	0.614	0.386
I21 Acute myocardial infarction	0.613	0.387
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs	0.613	0.387
C38 Malignant neoplasm of heart, mediastinum and pleura	0.613	0.387
C32 Malignant neoplasm of larynx	0.613	0.387
C31 Malignant neoplasm of accessory sinuses	0.613	0.387
C30 Malignant neoplasm of nasal cavity and middle ear	0.613	0.387
C37 Malignant neoplasm of thymus	0.613	0.387
C33 Malignant neoplasm of trachea	0.613	0.387
F22 Persistent delusional disorders	0.612	0.388
C18.2 Ascending colon	0.612	0.388
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.611	0.389
M25.56 Pain in joint (Lower leg)	0.610	0.390
Z76 Persons encountering health services in other circumstances	0.610	0.390
Z73 Problems related to life-management difficulty	0.610	0.390
Z70 Counselling related to sexual attitude, behaviour and orientation	0.610	0.390
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.609	0.391
S82.3 Fracture of lower end of tibia	0.609	0.391
S64.9 Injury of unspecified nerve at wrist and hand level	0.609	0.391
S64.8 Injury of other nerves at wrist and hand level	0.609	0.391
S64.7 Injury of multiple nerves at wrist and hand level	0.609	0.391
S64.3 Injury of digital nerve of thumb	0.609	0.391
S64.2 Injury of radial nerve at wrist and hand level	0.609	0.391
S64.1 Injury of median nerve at wrist and hand level	0.609	0.391
S64.0 Injury of ulnar nerve at wrist and hand level	0.609	0.391
G80-G83 Cerebral palsy and other paralytic syndromes	0.609	0.391
M25.58 Pain in joint (Other)	0.607	0.393
M25.53 Pain in joint (Forearm)	0.607	0.393
M25.52 Pain in joint (Upper arm)	0.607	0.393
M25.50 Pain in joint (Multiple sites)	0.607	0.393
L60 Nail disorders	0.607	0.393
T85.4 Mechanical complication of breast prosthesis and implant	0.606	0.393
Z45 Adjustment and management of implanted device	0.606	0.394
Z42.1 Follow-up care involving plastic surgery of breast	0.606	0.394
O80-O84 Delivery	0.606	0.394
S69.9 Unspecified injury of wrist and hand	0.605	0.395
S60.9 Superficial injury of wrist and hand, unspecified	0.604	0.396
S82.50 Fracture of medial malleolus (closed)	0.604	0.396
M22 Disorders of patella	0.604	0.396
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.604	0.396
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.604	0.396
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.604	0.396
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.604	0.396
T46 Poisoning by agents primarily affecting the cardiovascular system	0.604	0.396
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.604	0.396
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.604	0.396
T41 Poisoning by anaesthetics and therapeutic gases	0.604	0.396
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.604	0.396
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.604	0.396
T36 Poisoning by systemic antibiotics	0.604	0.396
M75 Shoulder lesions	0.603	0.397
C68 Malignant neoplasm of other and unspecified urinary organs	0.602	0.398
C66 Malignant neoplasm of ureter	0.602	0.398
C65 Malignant neoplasm of renal pelvis	0.602	0.398
F20 Schizophrenia	0.602	0.398
S81.7 Multiple open wounds of lower leg	0.601	0.399
S81.0 Open wound of knee	0.601	0.399
H36.8 Other retinal disorders in diseases classified elsewhere	0.601	0.399
I24.1 Dressler's syndrome	0.600	0.399
H04.2 Epiphora	0.600	0.400
I49.3 Ventricular premature depolarisation	0.600	0.400
S01 Open wound of head	0.600	0.400
S49 Other and unspecified injuries of shoulder and upper arm	0.600	0.400
D22 Melanocytic naevi	0.600	0.400
S61.1 Open wound of finger(s) with damage to nail	0.599	0.400
S92 Fracture of foot, except ankle	0.599	0.400
D68 Other coagulation defects	0.599	0.401
T85.9 Unspecified complication of internal prosthetic device, implant and graft	0.598	0.401
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts	0.598	0.401
T85.1 Mechanical complication of implanted electronic stimulator of nervous system	0.598	0.401
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt	0.598	0.401
I49.9 Cardiac arrhythmia, unspecified	0.598	0.402
S99 Other and unspecified injuries of ankle and foot	0.597	0.403
S98 Traumatic amputation of ankle and foot	0.597	0.403
S97 Crushing injury of ankle and foot	0.597	0.403
S96 Injury of muscle and tendon at ankle and foot level	0.597	0.403
S95 Injury of blood vessels at ankle and foot level	0.597	0.403
S94 Injury of nerves at ankle and foot level	0.597	0.403
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.597	0.403
S90 Superficial injury of ankle and foot	0.597	0.403
C73 Malignant neoplasm of thyroid gland	0.597	0.403
Z89.9 Acquired absence of limb, unspecified	0.597	0.403
Z89.8 Acquired absence of upper and lower limbs [any level]	0.597	0.403
Z89.7 Acquired absence of both lower limbs [any level, except toes alone]	0.597	0.403
Z89.6 Acquired absence of leg above knee	0.597	0.403
Z89.3 Acquired absence of both upper limbs [any level]	0.597	0.403
Z89.2 Acquired absence of upper limb above wrist	0.597	0.403
Z89.1 Acquired absence of hand and wrist	0.597	0.403
Z89.0 Acquired absence of finger(s) [including thumb], unilateral	0.597	0.403
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.596	0.404
Z11.0 Special screening examination for intestinal infectious diseases	0.595	0.405
Z36 Antenatal screening	0.595	0.405
H35.4 Peripheral retinal degeneration	0.594	0.406
M24.1 Other articular cartilage disorders	0.594	0.406
Z02 Examination and encounter for administrative purposes	0.594	0.406
Z85.5 Personal history of malignant neoplasm of urinary tract	0.593	0.407

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations