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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs114531066
log Bayes Factor = 12.089
Chromosome 1   position 241,879,430  (GRCh37) Explore rs114531066 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter X Diseases of the respiratory system
1.000 0.000 0.000
J40-J47 Chronic lower respiratory diseases
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.999 0.001 0.000
J44 Other chronic obstructive pulmonary disease
0.999 0.001 0.000
R50-R69 General symptoms and signs
0.999 0.001 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.997 0.003 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.993 0.007 0.000
R63 Symptoms and signs concerning food and fluid intake
0.989 0.011 0.000
Chapter XXI Factors influencing health status and contact with health services
0.988 0.012 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.986 0.014 0.000
R21 Rash and other nonspecific skin eruption
0.980 0.020 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.972 0.028 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.972 0.028 0.000
Chapter XX External causes of morbidity and mortality
0.970 0.030 0.000
J09-J18 Influenza and pneumonia
0.969 0.031 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.967 0.033 0.000
R63.0 Anorexia
0.965 0.035 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.956 0.044 0.000
M70-M79 Other soft tissue disorders
0.949 0.051 0.000
J43 Emphysema
0.947 0.053 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.944 0.056 0.000
J18 Pneumonia, organism unspecified
0.941 0.059 0.000
S70-S79 Injuries to the hip and thigh
0.941 0.059 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.938 0.062 0.000
R50 Fever of unknown origin
0.930 0.070 0.000
Chapter VI Diseases of the nervous system
0.929 0.071 0.000
J18.9 Pneumonia, unspecified
0.922 0.078 0.000
R52 Pain, not elsewhere classified
0.917 0.083 0.000
R63.4 Abnormal weight loss
0.914 0.086 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.914 0.086 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.913 0.087 0.000
J43.9 Emphysema, unspecified
0.910 0.090 0.000
J46 Status asthmaticus
0.903 0.097 0.000
Z22 Carrier of infectious disease
0.902 0.098 0.000
J20-J22 Other acute lower respiratory infections
0.898 0.102 0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.893 0.107 0.000
R59 Enlarged lymph nodes
0.889 0.111 0.000
M05-M14 Inflammatory polyarthropathies
0.889 0.111 0.000
J84 Other interstitial pulmonary diseases
0.888 0.112 0.000
T39.0 Salicylates
0.888 0.112 0.000
Z03 Medical observation and evaluation for suspected diseases and conditions
0.886 0.114 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.885 0.115 0.000
J47 Bronchiectasis
0.885 0.115 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.875 0.125 0.000
M79.8 Other specified soft tissue disorders
0.873 0.127 0.000
Z22.3 Carrier of other specified bacterial diseases
0.873 0.127 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.872 0.128 0.000
R50.9 Fever, unspecified
0.870 0.130 0.000
M79.6 Pain in limb
0.870 0.130 0.000
R53 Malaise and fatigue
0.869 0.131 0.000
Z13 Special screening examination for other diseases and disorders
0.862 0.138 0.000
Chapter IX Diseases of the circulatory system
0.861 0.139 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.859 0.141 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.857 0.143 0.000
T39.1 4-Aminophenol derivatives
0.856 0.144 0.000
Z13.9 Special screening examination, unspecified
0.854 0.146 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.854 0.146 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.853 0.147 0.000
R23 Other skin changes
0.849 0.151 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.849 0.151 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.848 0.152 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.848 0.152 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.845 0.155 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.844 0.156 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.843 0.157 0.000
W00-W19 Falls
0.837 0.163 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.837 0.163 0.000
Chapter V Mental and behavioural disorders
0.833 0.167 0.000
Z60 Problems related to social environment
0.833 0.167 0.000
Z03.4 Observation for suspected myocardial infarction
0.831 0.169 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.829 0.171 0.000
I26 Pulmonary embolism
0.827 0.173 0.000
S72 Fracture of femur
0.826 0.174 0.000
J22 Unspecified acute lower respiratory infection
0.826 0.174 0.000
R60 Oedema, not elsewhere classified
0.824 0.176 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.824 0.176 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.823 0.177 0.000
J84.1 Other interstitial pulmonary diseases with fibrosis
0.821 0.179 0.000
Chapter XXII Codes for special purposes
0.821 0.179 0.000
R57 Shock, not elsewhere classified
0.817 0.183 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.817 0.183 0.000
M13 Other arthritis
0.817 0.183 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.816 0.184 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.813 0.187 0.000
Y83.6 Removal of other organ (partial) (total)
0.812 0.188 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.810 0.190 0.000
R52.2 Other chronic pain
0.809 0.191 0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.808 0.192 0.000
J81 Pulmonary oedema
0.808 0.192 0.000
I27 Other pulmonary heart diseases
0.806 0.194 0.000
V40-V49 Car occupant injured in transport accident
0.804 0.196 0.000
E50-E64 Other nutritional deficiencies
0.803 0.197 0.000
S80-S89 Injuries to the knee and lower leg
0.802 0.198 0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip
0.798 0.202 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.795 0.205 0.000
M79.63 Pain in limb (Forearm)
0.793 0.207 0.000
Z03.5 Observation for other suspected cardiovascular diseases
0.793 0.207 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.793 0.207 0.000
Z04 Examination and observation for other reasons
0.790 0.210 0.000
M91-M94 Chondropathies
0.789 0.211 0.000
R59.0 Localised enlarged lymph nodes
0.788 0.212 0.000
R52.1 Chronic intractable pain
0.782 0.218 0.000
R61 Hyperhidrosis
0.780 0.220 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.779 0.221 0.000
G35 Multiple sclerosis
0.778 0.222 0.000
S71 Open wound of hip and thigh
0.778 0.222 0.000
X60-X84 Intentional self-harm
0.776 0.224 0.000
Z60.2 Living alone
0.775 0.225 0.000
M86-M90 Other osteopathies
0.775 0.225 0.000
M79.60 Pain in limb (Multiple sites)
0.774 0.226 0.000
R26 Abnormalities of gait and mobility
0.774 0.226 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.773 0.227 0.000
R22.9 Localised swelling, mass and lump, unspecified
0.772 0.228 0.000
T66-T78 Other and unspecified effects of external causes
0.770 0.230 0.000
Chapter I Certain infectious and parasitic diseases
0.770 0.230 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.769 0.231 0.000
R22.4 Localised swelling, mass and lump, lower limb
0.767 0.233 0.000
M65-M68 Disorders of synovium and tendon
0.767 0.233 0.000
R58 Haemorrhage, not elsewhere classified
0.766 0.234 0.000
M13.9 Arthritis, unspecified
0.764 0.236 0.000
M79.84 Other specified soft tissue disorders (Hand)
0.763 0.237 0.000
Y83.3 Surgical operation with formation of external stoma
0.762 0.238 0.000
W20-W49 Exposure to inanimate mechanical forces
0.761 0.239 0.000
T42.4 Benzodiazepines
0.761 0.239 0.000
Z21 Asymptomatic human immunodeficiency virus [HIV] infection status
0.759 0.241 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.759 0.241 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.759 0.241 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.758 0.242 0.000
M79.1 Myalgia
0.755 0.245 0.000
J95-J99 Other diseases of the respiratory system
0.752 0.248 0.000
E53 Deficiency of other B group vitamins
0.752 0.248 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.752 0.248 0.000
Z03.9 Observation for suspected disease or condition, unspecified
0.751 0.249 0.000
M79.86 Other specified soft tissue disorders (Lower leg)
0.748 0.252 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.748 0.252 0.000
J60-J70 Lung diseases due to external agents
0.748 0.252 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.746 0.254 0.000
M77 Other enthesopathies
0.746 0.254 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.746 0.254 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.745 0.255 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.744 0.256 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.742 0.258 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.740 0.260 0.000
G90-G99 Other disorders of the nervous system
0.740 0.260 0.000
M80-M85 Disorders of bone density and structure
0.740 0.260 0.000
M40-M43 Deforming dorsopathies
0.735 0.265 0.000
M79.0 Rheumatism, unspecified
0.735 0.265 0.000
L03 Cellulitis
0.735 0.265 0.000
J80 Adult respiratory distress syndrome
0.733 0.267 0.000
T51 Toxic effect of alcohol
0.733 0.267 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.731 0.269 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.730 0.270 0.000
X50-X57 Overexertion, travel and privation
0.730 0.270 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.729 0.271 0.000
J42 Unspecified chronic bronchitis
0.728 0.272 0.000
W19 Unspecified fall
0.728 0.272 0.000
Chapter VII Diseases of the eye and adnexa
0.728 0.272 0.000
I05-I09 Chronic rheumatic heart diseases
0.726 0.274 0.000
R23.0 Cyanosis
0.725 0.275 0.000
S72.0 Fracture of neck of femur
0.724 0.276 0.000
X20-X29 Contact with venomous animals and plants
0.723 0.277 0.000
T43.2 Other and unspecified antidepressants
0.721 0.279 0.000
S20-S29 Injuries to the thorax
0.720 0.280 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
J41 Simple and mucopurulent chronic bronchitis
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S10-S19 Injuries to the neck
0.717 0.283 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.716 0.284 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.716 0.284 0.000
R62 Lack of expected normal physiological development
0.716 0.284 0.000
R64 Cachexia
0.716 0.284 0.000
E53.8 Deficiency of other specified B group vitamins
0.716 0.284 0.000
M13.90 Arthritis, unspecified (Multiple sites)
0.715 0.285 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.715 0.285 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.715 0.285 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.715 0.285 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.715 0.285 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.715 0.285 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.715 0.285 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.715 0.285 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.715 0.285 0.000
T36 Poisoning by systemic antibiotics
0.715 0.285 0.000
R50.0 Fever with chills
0.714 0.285 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.714 0.286 0.000
R60.0 Localised oedema
0.712 0.288 0.000
R59.9 Enlarged lymph nodes, unspecified
0.711 0.289 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.711 0.289 0.000
I27.2 Other secondary pulmonary hypertension
0.710 0.290 0.000
Z04.8 Examination and observation for other specified reasons
0.710 0.290 0.000
I27.0 Primary pulmonary hypertension
0.710 0.290 0.000
R63.6 Insufficient intake of food and water due to self neglect
0.709 0.291 0.000
R63.5 Abnormal weight gain
0.709 0.291 0.000
R63.3 Feeding difficulties and mismanagement
0.709 0.291 0.000
R63.2 Polyphagia
0.709 0.291 0.000
R63.1 Polydipsia
0.709 0.291 0.000
Z63 Other problems related to primary support group, including family circumstances
0.709 0.291 0.000
R63.8 Other symptoms and signs concerning food and fluid intake
0.709 0.291 0.000
B95-B98 Bacterial, viral and other infectious agents
0.708 0.292 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.708 0.292 0.000
F30-F39 Mood [affective] disorders
0.707 0.293 0.000
F43 Reaction to severe stress, and adjustment disorders
0.706 0.294 0.000
L82 Seborrhoeic keratosis
0.706 0.294 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.703 0.297 0.000
Chapter II Neoplasms
0.703 0.297 0.000
L85 Other epidermal thickening
0.702 0.297 0.000
M07 Psoriatic and enteropathic arthropathies
0.701 0.299 0.000
J84.9 Interstitial pulmonary disease, unspecified
0.701 0.299 0.000
T93 Sequelae of injuries of lower limb
0.700 0.300 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.700 0.300 0.000
Q21 Congenital malformations of cardiac septa
0.700 0.300 0.000
S60-S69 Injuries to the wrist and hand
0.699 0.301 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.698 0.302 0.000
R69 Unknown and unspecified causes of morbidity
0.698 0.302 0.000
M60-M63 Disorders of muscles
0.697 0.303 0.000
M00-M03 Infectious arthropathies
0.697 0.303 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.696 0.304 0.000
Y35-Y36 Legal intervention and operations of war
0.696 0.304 0.000
Y10-Y34 Event of undetermined intent
0.696 0.304 0.000
Y00-Y09 Assault
0.696 0.304 0.000
X85-X99 Assault
0.696 0.304 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.696 0.304 0.000
X30-X39 Exposure to forces of nature
0.696 0.304 0.000
X10-X19 Contact with heat and hot substances
0.696 0.304 0.000
X00-X09 Exposure to smoke, fire and flames
0.696 0.304 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.696 0.304 0.000
W75-W84 Other accidental threats to breathing
0.696 0.304 0.000
W65-W74 Accidental drowning and submersion
0.696 0.304 0.000
W50-W64 Exposure to animate mechanical forces
0.696 0.304 0.000
V98-V99 Other and unspecified transport accidents
0.696 0.304 0.000
V95-V97 Air and space transport accidents
0.696 0.304 0.000
V90-V94 Water transport accidents
0.696 0.304 0.000
V80-V89 Other land transport accidents
0.696 0.304 0.000
V70-V79 Bus occupant injured in transport accident
0.696 0.304 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.696 0.304 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.696 0.304 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.696 0.304 0.000
V01-V09 Pedestrian injured in transport accident
0.696 0.304 0.000
E55 Vitamin D deficiency
0.695 0.305 0.000
S73.0 Dislocation of hip
0.695 0.305 0.000
J17 Pneumonia in diseases classified elsewhere
0.695 0.305 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.695 0.305 0.000
J12 Viral pneumonia, not elsewhere classified
0.695 0.305 0.000
J11 Influenza, virus not identified
0.695 0.305 0.000
J14 Pneumonia due to Haemophilus influenzae
0.695 0.305 0.000
J09 Influenza due to certain identified influenza virus
0.695 0.305 0.000
J10 Influenza due to identified influenza virus
0.695 0.305 0.000
Z57 Occupational exposure to risk-factors
0.694 0.306 0.000
J18.1 Lobar pneumonia, unspecified
0.694 0.306 0.000
V20-V29 Motorcycle rider injured in transport accident
0.693 0.307 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.693 0.307 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.693 0.307 0.000
T39.4 Antirheumatics, not elsewhere classified
0.693 0.307 0.000
T39.2 Pyrazolone derivatives
0.693 0.307 0.000
R68 Other general symptoms and signs
0.690 0.310 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.690 0.310 0.000
M13.99 Arthritis, unspecified (Site unspecified)
0.689 0.311 0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified
0.688 0.312 0.000
Z03.6 Observation for suspected toxic effect from ingested substance
0.687 0.313 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.687 0.313 0.000
J82 Pulmonary eosinophilia, not elsewhere classified
0.686 0.314 0.000
R55 Syncope and collapse
0.686 0.314 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.686 0.314 0.000
T79-T79 Certain early complications of trauma
0.684 0.315 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.683 0.317 0.000
M10 Gout
0.682 0.318 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.682 0.318 0.000
S50-S59 Injuries to the elbow and forearm
0.682 0.318 0.000
M76 Enthesopathies of lower limb, excluding foot
0.681 0.319 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.681 0.319 0.000
M71 Other bursopathies
0.681 0.319 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.681 0.319 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.680 0.320 0.000
Z74 Problems related to care-provider dependency
0.680 0.320 0.000
J43.8 Other emphysema
0.679 0.321 0.000
J43.2 Centrilobular emphysema
0.679 0.321 0.000
J43.1 Panlobular emphysema
0.679 0.321 0.000
J43.0 MacLeod's syndrome
0.679 0.321 0.000
D73 Diseases of spleen
0.679 0.321 0.000
R26.8 Other and unspecified abnormalities of gait and mobility
0.678 0.322 0.000
M79.82 Other specified soft tissue disorders (Upper arm)
0.678 0.322 0.000
S70 Superficial injury of hip and thigh
0.678 0.322 0.000
M79.7 Fibromyalgia
0.678 0.322 0.000
Z28 Immunisation not carried out
0.677 0.323 0.000
Z27 Need for immunisation against combinations of infectious diseases
0.677 0.323 0.000
Z26 Need for immunisation against other single infectious diseases
0.677 0.323 0.000
Z25 Need for immunisation against other single viral diseases
0.677 0.323 0.000
Z24 Need for immunisation against certain single viral diseases
0.677 0.323 0.000
Z23 Need for immunisation against single bacterial diseases
0.677 0.323 0.000
Z20 Contact with and exposure to communicable diseases
0.677 0.323 0.000
S80 Superficial injury of lower leg
0.676 0.324 0.000
S32 Fracture of lumbar spine and pelvis
0.676 0.324 0.000
W19.9 Unspecified place
0.676 0.324 0.000
J18.8 Other pneumonia, organism unspecified
0.675 0.325 0.000
J18.2 Hypostatic pneumonia, unspecified
0.675 0.325 0.000
M79.5 Residual foreign body in soft tissue
0.675 0.325 0.000
M79.62 Pain in limb (Upper arm)
0.675 0.325 0.000
V10-V19 Pedal cyclist injured in transport accident
0.675 0.325 0.000
S78 Traumatic amputation of hip and thigh
0.675 0.325 0.000
S77 Crushing injury of hip and thigh
0.675 0.325 0.000
S76 Injury of muscle and tendon at hip and thigh level
0.675 0.325 0.000
S75 Injury of blood vessels at hip and thigh level
0.675 0.325 0.000
S74 Injury of nerves at hip and thigh level
0.675 0.325 0.000
M79.9 Soft tissue disorder, unspecified
0.672 0.328 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.672 0.328 0.000
M79.3 Panniculitis, unspecified
0.672 0.328 0.000
M79.2 Neuralgia and neuritis, unspecified
0.672 0.328 0.000
M79.85 Other specified soft tissue disorders (Pelvic region and thigh)
0.671 0.329 0.000
R22.3 Localised swelling, mass and lump, upper limb
0.671 0.329 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.671 0.329 0.000
O85-O92 Complications predominantly related to the puerperium
0.668 0.332 0.000
R50.8 Other specified fever
0.667 0.332 0.000
T40.2 Other opioids
0.667 0.333 0.000
R50.2 Drug-induced fever
0.667 0.333 0.000
R50.1 Persistent fever
0.667 0.333 0.000
E61 Deficiency of other nutrient elements
0.667 0.333 0.000
Q50-Q56 Congenital malformations of genital organs
0.665 0.335 0.000
Y83.0 Surgical operation with transplant of whole organ
0.665 0.335 0.000
Z51 Other medical care
0.664 0.336 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.662 0.338 0.000
J15.2 Pneumonia due to staphylococcus
0.661 0.339 0.000
S71.1 Open wound of thigh
0.661 0.339 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.660 0.339 0.000
R22.0 Localised swelling, mass and lump, head
0.660 0.339 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.659 0.341 0.000
G57 Mononeuropathies of lower limb
0.658 0.342 0.000
F43.2 Adjustment disorders
0.658 0.342 0.000
F31 Bipolar affective disorder
0.658 0.342 0.000
S72.3 Fracture of shaft of femur
0.658 0.342 0.000
M94 Other disorders of cartilage
0.657 0.343 0.000
J18.0 Bronchopneumonia, unspecified
0.657 0.343 0.000
R57.2 Septic shock
0.656 0.344 0.000
D80-D89 Certain disorders involving the immune mechanism
0.655 0.345 0.000
Z10 Routine general health check-up of defined subpopulation
0.655 0.345 0.000
Z65 Problems related to other psychosocial circumstances
0.655 0.345 0.000
Z64 Problems related to certain psychosocial circumstances
0.655 0.345 0.000
Z62 Other problems related to upbringing
0.655 0.345 0.000
Z61 Problems related to negative life events in childhood
0.655 0.345 0.000
Z59 Problems related to housing and economic circumstances
0.655 0.345 0.000
Z58 Problems related to physical environment
0.655 0.345 0.000
Z56 Problems related to employment and unemployment
0.655 0.345 0.000
Z55 Problems related to education and literacy
0.655 0.345 0.000
Z29 Need for other prophylactic measures
0.654 0.345 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.654 0.346 0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards
0.654 0.346 0.000
G70-G73 Diseases of myoneural junction and muscle
0.654 0.346 0.000
R52.9 Pain, unspecified
0.654 0.346 0.000
C64-C68 Malignant neoplasms of urinary tract
0.654 0.346 0.000
L89 Decubitus ulcer
0.653 0.347 0.000
L84 Corns and callosities
0.651 0.349 0.000
Z03.1 Observation for suspected malignant neoplasm
0.651 0.349 0.000
Z51.4 Preparatory care for treatment, not elsewhere classified
0.651 0.349 0.000
Z13.5 Special screening examination for eye and ear disorders
0.651 0.349 0.000
F80-F89 Disorders of psychological development
0.651 0.349 0.000
S72.00 Fracture of neck of femur (closed)
0.651 0.349 0.000
Q21.1 Atrial septal defect
0.650 0.350 0.000
R23.1 Pallor
0.650 0.350 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.650 0.350 0.000
T91 Sequelae of injuries of neck and trunk
0.649 0.351 0.000
H55-H59 Other disorders of eye and adnexa
0.648 0.352 0.000
R52.0 Acute pain
0.647 0.353 0.000
G37 Other demyelinating diseases of central nervous system
0.647 0.353 0.000
Z22.9 Carrier of infectious disease, unspecified
0.647 0.353 0.000
Z22.8 Carrier of other infectious diseases
0.647 0.353 0.000
Z22.6 Carrier of human T-lymphotropic virus type 1 [HTLV-1] infection
0.647 0.353 0.000
Z22.5 Carrier of viral hepatitis
0.647 0.353 0.000
Z22.4 Carrier of infections with a predominantly sexual mode of transmission
0.647 0.353 0.000
Z22.2 Carrier of diphtheria
0.647 0.353 0.000
Z22.1 Carrier of other intestinal infectious diseases
0.647 0.353 0.000
Z22.0 Carrier of typhoid
0.647 0.353 0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.646 0.354 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.645 0.355 0.000
J21 Acute bronchiolitis
0.644 0.356 0.000
J20 Acute bronchitis
0.644 0.356 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.644 0.356 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.643 0.357 0.000
V48 Car occupant injured in noncollision transport accident
0.643 0.357 0.000
J15.4 Pneumonia due to other streptococci
0.643 0.357 0.000
J45 Asthma
0.643 0.357 0.000
S79 Other and unspecified injuries of hip and thigh
0.642 0.357 0.000
F40 Phobic anxiety disorders
0.642 0.358 0.000
L03.0 Cellulitis of finger and toe
0.642 0.358 0.000
R22.7 Localised swelling, mass and lump, multiple sites
0.640 0.360 0.000
Z36 Antenatal screening
0.640 0.360 0.000
D00-D09 In situ neoplasms
0.638 0.362 0.000
M14 Arthropathies in other diseases classified elsewhere
0.637 0.363 0.000
M12 Other specific arthropathies
0.637 0.363 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.637 0.363 0.000
M08 Juvenile arthritis
0.637 0.363 0.000
J84.8 Other specified interstitial pulmonary diseases
0.636 0.363 0.000
J84.0 Alveolar and parietoalveolar conditions
0.636 0.363 0.000
L03.1 Cellulitis of other parts of limb
0.636 0.364 0.000
V49 Car occupant injured in other and unspecified transport accidents
0.636 0.364 0.000
H02 Other disorders of eyelid
0.636 0.364 0.000
Y83.5 Amputation of limb(s)
0.635 0.365 0.000
Z03.2 Observation for suspected mental and behavioural disorders
0.635 0.365 0.000
Z03.0 Observation for suspected tuberculosis
0.635 0.365 0.000
L10-L14 Bullous disorders
0.635 0.365 0.000
G61 Inflammatory polyneuropathy
0.635 0.365 0.000
Q00-Q07 Congenital malformations of the nervous system
0.634 0.366 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.634 0.366 0.000
R25 Abnormal involuntary movements
0.633 0.367 0.000
D68 Other coagulation defects
0.632 0.368 0.000
R57.0 Cardiogenic shock
0.631 0.369 0.000
Z04.9 Examination and observation for unspecified reason
0.630 0.369 0.000
L83 Acanthosis nigricans
0.630 0.370 0.000
L03.3 Cellulitis of trunk
0.630 0.370 0.000
O48 Prolonged pregnancy
0.630 0.370 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.630 0.370 0.000
M06 Other rheumatoid arthritis
0.629 0.371 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.628 0.372 0.000
Q80-Q89 Other congenital malformations
0.628 0.372 0.000
Q35-Q37 Cleft lip and cleft palate
0.628 0.372 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.628 0.372 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.628 0.372 0.000
T51.0 Ethanol
0.627 0.373 0.000
M79.88 Other specified soft tissue disorders (Other)
0.626 0.374 0.000
M79.83 Other specified soft tissue disorders (Forearm)
0.626 0.374 0.000
M79.81 Other specified soft tissue disorders (Shoulder region)
0.626 0.374 0.000
M79.80 Other specified soft tissue disorders (Multiple sites)
0.626 0.374 0.000
G62 Other polyneuropathies
0.626 0.374 0.000
Z08.7 Follow-up examination after combined treatment for malignant neoplasm
0.626 0.374 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.624 0.376 0.000
M79.19 Myalgia (Site unspecified)
0.624 0.376 0.000
R61.9 Hyperhidrosis, unspecified
0.624 0.376 0.000
M79.68 Pain in limb (Other)
0.624 0.376 0.000
M79.61 Pain in limb (Shoulder region)
0.624 0.376 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.623 0.377 0.000
S90-S99 Injuries to the ankle and foot
0.623 0.377 0.000
T92 Sequelae of injuries of upper limb
0.619 0.380 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.618 0.382 0.000
Z13.8 Special screening examination for other specified diseases and disorders
0.618 0.382 0.000
Z13.7 Special screening examination for congenital malformations, deformations and chromosomal abnormalities
0.618 0.382 0.000
Z13.4 Special screening examination for certain developmental disorders in childhood
0.618 0.382 0.000
Z13.3 Special screening examination for mental and behavioural disorders
0.618 0.382 0.000
Z13.2 Special screening examination for nutritional disorders
0.618 0.382 0.000
Z13.1 Special screening examination for diabetes mellitus
0.618 0.382 0.000
M79.89 Other specified soft tissue disorders (Site unspecified)
0.618 0.382 0.000
E55.9 Vitamin D deficiency, unspecified
0.618 0.382 0.000
C67 Malignant neoplasm of bladder
0.618 0.382 0.000
F42 Obsessive-compulsive disorder
0.617 0.383 0.000
I00-I02 Acute rheumatic fever
0.617 0.383 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.616 0.383 0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.616 0.384 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.616 0.384 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.616 0.384 0.000
T42.3 Barbiturates
0.616 0.384 0.000
T42.2 Succinimides and oxazolidinediones
0.616 0.384 0.000
T42.1 Iminostilbenes
0.616 0.384 0.000
T42.0 Hydantoin derivatives
0.616 0.384 0.000
E20-E35 Disorders of other endocrine glands
0.616 0.384 0.000
X63 Intentional self-poisoning by and exposure to other drugs acting on the autonomic nervous system
0.615 0.385 0.000
T40.4 Other synthetic narcotics
0.615 0.385 0.000
G09 Sequelae of inflammatory diseases of central nervous system
0.615 0.385 0.000
T43.9 Psychotropic drug, unspecified
0.614 0.385 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.614 0.385 0.000
T43.6 Psychostimulants with abuse potential
0.614 0.385 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.614 0.385 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.614 0.385 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.614 0.385 0.000
O44 Placenta praevia
0.614 0.386 0.000
M13.94 Arthritis, unspecified (Hand)
0.613 0.387 0.000
R26.2 Difficulty in walking, not elsewhere classified
0.612 0.388 0.000
I28 Other diseases of pulmonary vessels
0.612 0.388 0.000
M05 Seropositive rheumatoid arthritis
0.612 0.388 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.611 0.389 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.610 0.390 0.000
Y83.9 Surgical procedure, unspecified
0.610 0.390 0.000
R23.8 Other and unspecified skin changes
0.610 0.390 0.000
R26.3 Immobility
0.610 0.390 0.000
L50-L54 Urticaria and erythema
0.610 0.390 0.000
E40-E46 Malnutrition
0.609 0.391 0.000
U80 Agent resistant to penicillin and related antibiotics
0.609 0.391 0.000
R23.4 Changes in skin texture
0.609 0.391 0.000
R23.3 Spontaneous ecchymoses
0.609 0.391 0.000
R23.2 Flushing
0.609 0.391 0.000
R59.1 Generalised enlarged lymph nodes
0.609 0.391 0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis
0.609 0.391 0.000
S37 Injury of urinary and pelvic organs
0.609 0.391 0.000
S36 Injury of intra-abdominal organs
0.609 0.391 0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level
0.609 0.391 0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level
0.609 0.391 0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis
0.609 0.391 0.000
S31 Open wound of abdomen, lower back and pelvis
0.609 0.391 0.000
Z51.8 Other specified medical care
0.609 0.391 0.000
I27.9 Pulmonary heart disease, unspecified
0.609 0.391 0.000
G36 Other acute disseminated demyelination
0.608 0.392 0.000
S81 Open wound of lower leg
0.608 0.392 0.000
G57.6 Lesion of plantar nerve
0.607 0.393 0.000
G30-G32 Other degenerative diseases of the nervous system
0.606 0.393 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.606 0.394 0.000
W13 Fall from, out of or through building or structure
0.606 0.394 0.000
L03.8 Cellulitis of other sites
0.606 0.394 0.000
T78 Adverse effects, not elsewhere classified
0.606 0.394 0.000
T98 Sequelae of other and unspecified effects of external causes
0.605 0.394 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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