TreeWAS – Variant ID: rs114713670

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
Chapter XIII Diseases of the musculoskeletal system and connective tissue	1.000	0.000
# Top node	1.000	0.000
M20-M25 Other joint disorders	1.000	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	1.000	0.000
Chapter II Neoplasms	0.999	0.001
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.998	0.002
Chapter XI Diseases of the digestive system	0.997	0.003
M20 Acquired deformities of fingers and toes	0.996	0.004
C79 Secondary malignant neoplasm of other sites	0.995	0.005
Chapter IV Endocrine, nutritional and metabolic diseases	0.992	0.008
Chapter XV Pregnancy, childbirth and the puerperium	0.992	0.008
M50-M54 Other dorsopathies	0.986	0.014
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.984	0.016
Chapter V Mental and behavioural disorders	0.983	0.017
K90-K93 Other diseases of the digestive system	0.982	0.018
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.979	0.021
K50-K52 Noninfective enteritis and colitis	0.974	0.026
K92 Other diseases of digestive system	0.971	0.029
S80-S89 Injuries to the knee and lower leg	0.970	0.030
M20.4 Other hammer toe(s) (acquired)	0.955	0.045
Chapter X Diseases of the respiratory system	0.951	0.049
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.946	0.054
J09-J18 Influenza and pneumonia	0.945	0.055
M20.1 Hallux valgus (acquired)	0.945	0.055
M20.5 Other deformities of toe(s) (acquired)	0.943	0.057
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.942	0.058
M45-M49 Spondylopathies	0.941	0.059
E65-E68 Obesity and other hyperalimentation	0.936	0.064
S00-S09 Injuries to the head	0.936	0.064
J18 Pneumonia, organism unspecified	0.933	0.067
O60-O75 Complications of labour and delivery	0.929	0.071
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.929	0.071
K70-K77 Diseases of liver	0.928	0.072
C79.9 Secondary malignant neoplasm, unspecified site	0.927	0.073
C64-C68 Malignant neoplasms of urinary tract	0.919	0.081
J18.9 Pneumonia, unspecified	0.918	0.082
K92.1 Melaena	0.917	0.083
K52 Other non-infective gastro-enteritis and colitis	0.914	0.086
O00-O08 Pregnancy with abortive outcome	0.914	0.086
S20-S29 Injuries to the thorax	0.907	0.093
M54 Dorsalgia	0.902	0.098
K50 Crohn's disease [regional enteritis]	0.901	0.099
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.900	0.100
K92.0 Haematemesis	0.899	0.101
E20-E35 Disorders of other endocrine glands	0.898	0.102
M51 Other intervertebral disk disorders	0.897	0.103
E66 Obesity	0.896	0.104
M25 Other joint disorders, not elsewhere classified	0.895	0.105
F17 Mental and behavioural disorders due to use of tobacco	0.893	0.107
M21 Other acquired deformities of limbs	0.891	0.109
C79.3 Secondary malignant neoplasm of brain and cerebral meninges	0.890	0.110
F40-F48 Neurotic, stress-related and somatoform disorders	0.890	0.110
Chapter I Certain infectious and parasitic diseases	0.890	0.110
M50 Cervical disk disorders	0.885	0.115
C79.8 Secondary malignant neoplasm of other specified sites	0.885	0.115
M65-M68 Disorders of synovium and tendon	0.882	0.118
E70-E90 Metabolic disorders	0.880	0.120
Chapter VII Diseases of the eye and adnexa	0.879	0.121
C78.0 Secondary malignant neoplasm of lung	0.878	0.122
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum	0.878	0.122
C78.2 Secondary malignant neoplasm of pleura	0.877	0.122
F17.2 Dependence syndrome	0.877	0.123
S82 Fracture of lower leg, including ankle	0.875	0.125
E66.9 Obesity, unspecified	0.870	0.130
C34 Malignant neoplasm of bronchus and lung	0.869	0.131
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.869	0.131
T85 Complications of other internal prosthetic devices, implants and grafts	0.864	0.136
M47 Spondylosis	0.862	0.138
M24 Other specific joint derangements	0.855	0.145
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.855	0.145
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.851	0.149
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.848	0.152
K92.2 Gastro-intestinal haemorrhage, unspecified	0.848	0.152
K76 Other diseases of liver	0.842	0.158
D37-D48 Neoplasms of uncertain or unknown behaviour	0.838	0.162
M54.5 Low back pain	0.837	0.163
J60-J70 Lung diseases due to external agents	0.835	0.165
O72 Postpartum haemorrhage	0.834	0.166
O03 Spontaneous abortion	0.833	0.167
E10-E14 Diabetes mellitus	0.832	0.168
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.831	0.169
K76.0 Fatty (change of) liver, not elsewhere classified	0.827	0.173
J18.1 Lobar pneumonia, unspecified	0.826	0.174
S40-S49 Injuries to the shoulder and upper arm	0.822	0.178
E87 Other disorders of fluid, electrolyte and acid-base balance	0.818	0.182
M22 Disorders of patella	0.818	0.182
D69 Purpura and other haemorrhagic conditions	0.817	0.183
M48 Other spondylopathies	0.816	0.184
O02 Other abnormal products of conception	0.814	0.186
O80-O84 Delivery	0.813	0.187
C79.0 Secondary malignant neoplasm of kidney and renal pelvis	0.813	0.187
F10 Mental and behavioural disorders due to use of alcohol	0.812	0.188
K52.9 Non-infective gastro-enteritis and colitis, unspecified	0.809	0.191
M25.7 Osteophyte	0.808	0.192
K52.8 Other specified non-infective gastro-enteritis and colitis	0.808	0.192
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.806	0.194
D68 Other coagulation defects	0.806	0.194
M35 Other systemic involvement of connective tissue	0.803	0.197
M40-M43 Deforming dorsopathies	0.801	0.199
S82.5 Fracture of medial malleolus	0.800	0.200
C79.2 Secondary malignant neoplasm of skin	0.800	0.200
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.799	0.201
K75 Other inflammatory liver diseases	0.799	0.201
Chapter VI Diseases of the nervous system	0.798	0.202
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.798	0.202
C79.6 Secondary malignant neoplasm of ovary	0.796	0.204
J13 Pneumonia due to Streptococcus pneumoniae	0.795	0.205
K50.0 Crohn's disease of small intestine	0.793	0.207
J90-J94 Other diseases of pleura	0.790	0.210
S01 Open wound of head	0.790	0.210
M50.0 Cervical disk disorder with myelopathy	0.789	0.211
C67 Malignant neoplasm of bladder	0.785	0.215
S22 Fracture of rib(s), sternum and thoracic spine	0.783	0.217
K86 Other diseases of pancreas	0.783	0.217
C78.7 Secondary malignant neoplasm of liver	0.782	0.218
C34.9 Bronchus or lung, unspecified	0.780	0.220
E50-E64 Other nutritional deficiencies	0.780	0.220
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.780	0.220
T86 Failure and rejection of transplanted organs and tissues	0.778	0.222
S81 Open wound of lower leg	0.776	0.224
T88 Other complications of surgical and medical care, not elsewhere classified	0.775	0.225
E40-E46 Malnutrition	0.773	0.226
T80 Complications following infusion, transfusion and therapeutic injection	0.773	0.227
S02 Fracture of skull and facial bones	0.772	0.228
F30-F39 Mood [affective] disorders	0.772	0.228
E87.2 Acidosis	0.771	0.229
A00-A09 Intestinal infectious diseases	0.768	0.232
F40 Phobic anxiety disorders	0.765	0.235
H25-H28 Disorders of lens	0.765	0.235
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.765	0.235
C64 Malignant neoplasm of kidney, except renal pelvis	0.765	0.235
S82.8 Fractures of other parts of lower leg	0.765	0.235
E14 Unspecified diabetes mellitus	0.765	0.235
S70-S79 Injuries to the hip and thigh	0.764	0.236
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.763	0.237
M31 Other necrotising vasculopathies	0.759	0.241
C79.5 Secondary malignant neoplasm of bone and bone marrow	0.759	0.241
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.755	0.244
M51.0 Lumbar and other intervertebral disk disorders with myelopathy	0.755	0.245
K50.9 Crohn's disease, unspecified	0.755	0.245
J61 Pneumoconiosis due to asbestos and other mineral fibres	0.754	0.246
D50-D53 Nutritional anaemias	0.754	0.246
M51.2 Other specified intervertebral disk displacement	0.754	0.246
E22 Hyperfunction of pituitary gland	0.753	0.247
J17 Pneumonia in diseases classified elsewhere	0.752	0.248
M47.9 Spondylosis, unspecified	0.750	0.250
D69.6 Thrombocytopenia, unspecified	0.749	0.251
C79.7 Secondary malignant neoplasm of adrenal gland	0.749	0.251
M80-M85 Disorders of bone density and structure	0.749	0.251
Chapter VIII Diseases of the ear and mastoid process	0.748	0.252
S82.50 Fracture of medial malleolus (closed)	0.746	0.254
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts	0.746	0.254
S27 Injury of other and unspecified intrathoracic organs	0.746	0.254
O72.1 Other immediate postpartum haemorrhage	0.745	0.255
O70 Perineal laceration during delivery	0.744	0.256
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.744	0.256
O02.1 Missed abortion	0.743	0.257
G90-G99 Other disorders of the nervous system	0.742	0.258
S90-S99 Injuries to the ankle and foot	0.742	0.258
O03.9 Complete or unspecified, without complication	0.742	0.258
K65-K67 Diseases of peritoneum	0.741	0.258
M54.56 Low back pain (Lumbar region)	0.741	0.259
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.741	0.259
O63 Long labour	0.741	0.259
M65 Synovitis and tenosynovitis	0.741	0.259
S00 Superficial injury of head	0.740	0.260
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.740	0.260
M47.2 Other spondylosis with radiculopathy	0.739	0.261
M21.0 Valgus deformity, not elsewhere classified	0.738	0.262
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.738	0.262
S80 Superficial injury of lower leg	0.738	0.262
S06 Intracranial injury	0.737	0.263
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts	0.736	0.264
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee	0.736	0.264
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.736	0.264
O62 Abnormalities of forces of labour	0.735	0.265
T15-T19 Effects of foreign body entering through natural orifice	0.733	0.266
C65 Malignant neoplasm of renal pelvis	0.733	0.267
M67 Other disorders of synovium and tendon	0.733	0.267
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs	0.732	0.268
M25.76 Osteophyte (Lower leg)	0.730	0.270
T83.0 Mechanical complication of urinary (indwelling) catheter	0.729	0.271
S83.6 Sprain and strain of other and unspecified parts of knee	0.729	0.271
K82 Other diseases of gallbladder	0.728	0.272
S82.0 Fracture of patella	0.728	0.272
M91-M94 Chondropathies	0.727	0.272
M70-M79 Other soft tissue disorders	0.727	0.273
J95-J99 Other diseases of the respiratory system	0.727	0.273
M25.8 Other specified joint disorders	0.724	0.276
E28 Ovarian dysfunction	0.723	0.277
E86 Volume depletion	0.722	0.278
C34.1 Upper lobe, bronchus or lung	0.721	0.279
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.721	0.279
F43 Reaction to severe stress, and adjustment disorders	0.720	0.280
M50.3 Other cervical disk degeneration	0.720	0.280
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.718	0.282
T81 Complications of procedures, not elsewhere classified	0.718	0.282
M25.0 Haemarthrosis	0.718	0.282
M47.96 Spondylosis, unspecified (Lumbar region)	0.717	0.283
M60-M63 Disorders of muscles	0.717	0.283
M00-M03 Infectious arthropathies	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.717	0.283
M34 Systemic sclerosis	0.717	0.283
M33 Dermatopolymyositis	0.717	0.283
M32 Systemic lupus erythematosus	0.717	0.283
M30 Polyarteritis nodosa and related conditions	0.717	0.283
T33-T35 Frostbite	0.717	0.283
T26-T28 Burns and corrosions confined to eye and internal organs	0.717	0.283
T20-T25 Burns and corrosions of external body surface, specified by site	0.717	0.283
T00-T07 Injuries involving multiple body regions	0.717	0.283
S10-S19 Injuries to the neck	0.717	0.283
O20-O29 Other maternal disorders predominantly related to pregnancy	0.716	0.284
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.716	0.284
C40-C41 Malignant neoplasms of bone and articular cartilage	0.716	0.284
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.716	0.284
C76 Malignant neoplasm of other and ill-defined sites	0.716	0.284
M48.0 Spinal stenosis	0.715	0.285
S22.4 Multiple fractures of ribs	0.714	0.286
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.714	0.286
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system	0.713	0.287
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs	0.713	0.287
J15 Bacterial pneumonia, not elsewhere classified	0.713	0.287
A30-A49 Other bacterial diseases	0.713	0.287
O82 Single delivery by Caesarean section	0.711	0.289
M21.1 Varus deformity, not elsewhere classified	0.711	0.289
O85-O92 Complications predominantly related to the puerperium	0.711	0.289
M54.57 Low back pain (Lumbosacral region)	0.711	0.289
O42 Premature rupture of membranes	0.710	0.290
K50.1 Crohn's disease of large intestine	0.710	0.290
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.709	0.291
C78.5 Secondary malignant neoplasm of large intestine and rectum	0.708	0.292
C32 Malignant neoplasm of larynx	0.706	0.294
C78.4 Secondary malignant neoplasm of small intestine	0.705	0.294
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs	0.705	0.294
C78.1 Secondary malignant neoplasm of mediastinum	0.705	0.294
M24.1 Other articular cartilage disorders	0.705	0.295
M86-M90 Other osteopathies	0.705	0.295
H26 Other cataract	0.705	0.295
F99-F99 Unspecified mental disorder	0.704	0.295
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.704	0.295
F80-F89 Disorders of psychological development	0.704	0.295
F70-F79 Mental retardation	0.704	0.295
F60-F69 Disorders of adult personality and behaviour	0.704	0.295
O75 Other complications of labour and delivery, not elsewhere classified	0.704	0.296
O47 False labour	0.704	0.296
K93 Disorders of other digestive organs in diseases classified elsewhere	0.704	0.296
M20.3 Other deformity of hallux (acquired)	0.702	0.298
K72 Hepatic failure, not elsewhere classified	0.702	0.298
T87 Complications peculiar to reattachment and amputation	0.702	0.298
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.701	0.298
O36 Maternal care for other known or suspected foetal problems	0.701	0.299
O43 Placental disorders	0.701	0.299
M25.77 Osteophyte (Ankle and foot)	0.701	0.299
S89 Other and unspecified injuries of lower leg	0.700	0.300
E88 Other metabolic disorders	0.700	0.300
M21.2 Flexion deformity	0.699	0.301
G35-G37 Demyelinating diseases of the central nervous system	0.698	0.302
F00-F09 Organic, including symptomatic, mental disorders	0.698	0.302
J90 Pleural effusion, not elsewhere classified	0.698	0.302
Chapter XXI Factors influencing health status and contact with health services	0.697	0.303
K51 Ulcerative colitis	0.697	0.303
K92.8 Other specified diseases of digestive system	0.696	0.304
M50.1 Cervical disk disorder with radiculopathy	0.696	0.304
T83.3 Mechanical complication of intra-uterine contraceptive device	0.696	0.304
S88 Traumatic amputation of lower leg	0.696	0.304
S87 Crushing injury of lower leg	0.696	0.304
S86 Injury of muscle and tendon at lower leg level	0.696	0.304
S85 Injury of blood vessels at lower leg level	0.696	0.304
S84 Injury of nerves at lower leg level	0.696	0.304
M51.8 Other specified intervertebral disk disorders	0.695	0.305
D00-D09 In situ neoplasms	0.695	0.305
S09 Other and unspecified injuries of head	0.695	0.305
M54.4 Lumbago with sciatica	0.692	0.308
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.692	0.308
F41 Other anxiety disorders	0.692	0.308
A09 Diarrhoea and gastro-enteritis of presumed infectious origin	0.691	0.309
M25.9 Joint disorder, unspecified	0.690	0.310
M53 Other dorsopathies, not elsewhere classified	0.690	0.310
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.689	0.311
E85 Amyloidosis	0.689	0.311
Chapter XXII Codes for special purposes	0.688	0.311
H30-H36 Disorders of choroid and retina	0.688	0.312
T79-T79 Certain early complications of trauma	0.687	0.313
E14.9 Without complications	0.687	0.313
O64 Obstructed labour due to malposition and malpresentation of foetus	0.686	0.314
S82.80 Fractures of other parts of lower leg (closed)	0.686	0.314
O03.4 Incomplete, without complication	0.685	0.315
C34.0 Main bronchus	0.685	0.315
S20 Superficial injury of thorax	0.684	0.316
M22.4 Chondromalacia patellae	0.684	0.316
S81.0 Open wound of knee	0.684	0.316
F10.1 Harmful use	0.684	0.316
O72.2 Delayed and secondary postpartum haemorrhage	0.683	0.317
M46 Other inflammatory spondylopathies	0.682	0.318
O40 Polyhydramnios	0.680	0.320
Chapter XX External causes of morbidity and mortality	0.679	0.321
K75.9 Inflammatory liver disease, unspecified	0.679	0.321
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances	0.678	0.322
F18 Mental and behavioural disorders due to use of volatile solvents	0.678	0.322
F16 Mental and behavioural disorders due to use of hallucinogens	0.678	0.322
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine	0.678	0.322
F14 Mental and behavioural disorders due to use of cocaine	0.678	0.322
F13 Mental and behavioural disorders due to use of sedatives or hypnotics	0.678	0.322
F12 Mental and behavioural disorders due to use of cannabinoids	0.678	0.322
F11 Mental and behavioural disorders due to use of opioids	0.678	0.322
J16 Pneumonia due to other infectious organisms, not elsewhere classified	0.678	0.322
J12 Viral pneumonia, not elsewhere classified	0.678	0.322
J11 Influenza, virus not identified	0.678	0.322
J10 Influenza due to identified influenza virus	0.678	0.322
J14 Pneumonia due to Haemophilus influenzae	0.678	0.322
J09 Influenza due to certain identified influenza virus	0.678	0.322
H26.8 Other specified cataract	0.677	0.323
E23 Hypofunction and other disorders of pituitary gland	0.677	0.323
F40.2 Specific (isolated) phobias	0.676	0.324
M20.0 Deformity of finger(s)	0.676	0.324
D55-D59 Haemolytic anaemias	0.675	0.325
K85 Acute pancreatitis	0.675	0.325
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.675	0.325
E87.1 Hypo-osmolality and hyponatraemia	0.675	0.325
M49 Spondylopathies in diseases classified elsewhere	0.674	0.325
T66-T78 Other and unspecified effects of external causes	0.674	0.326
H10-H13 Disorders of conjunctiva	0.673	0.327
M54.9 Dorsalgia, unspecified	0.672	0.328
K86.3 Pseudocyst of pancreas	0.672	0.328
E67 Other hyperalimentation	0.671	0.329
E68 Sequelae of hyperalimentation	0.671	0.329
E65 Localised adiposity	0.671	0.329
D70-D77 Other diseases of blood and blood-forming organs	0.671	0.329
S08 Traumatic amputation of part of head	0.671	0.329
S07 Crushing injury of head	0.671	0.329
S05 Injury of eye and orbit	0.671	0.329
S04 Injury of cranial nerves	0.671	0.329
S03 Dislocation, sprain and strain of joints and ligaments of head	0.671	0.329
M43 Other deforming dorsopathies	0.670	0.330
K35-K38 Diseases of appendix	0.670	0.330
T81.4 Infection following a procedure, not elsewhere classified	0.670	0.330
K70 Alcoholic liver disease	0.669	0.331
J18.8 Other pneumonia, organism unspecified	0.669	0.331
J18.2 Hypostatic pneumonia, unspecified	0.669	0.331
B95-B98 Bacterial, viral and other infectious agents	0.668	0.331
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.667	0.332
K00-K14 Diseases of oral cavity, salivary glands and jaws	0.667	0.333
B90-B94 Sequelae of infectious and parasitic diseases	0.667	0.333
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.667	0.333
O74 Complications of anaesthesia during labour and delivery	0.666	0.334
O73 Retained placenta and membranes, without haemorrhage	0.666	0.334
O71 Other obstetric trauma	0.666	0.334
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified	0.666	0.334
O65 Obstructed labour due to maternal pelvic abnormality	0.666	0.334
O61 Failed induction of labour	0.666	0.334
O60 Preterm delivery	0.666	0.334
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs	0.666	0.334
C38 Malignant neoplasm of heart, mediastinum and pleura	0.666	0.334
C31 Malignant neoplasm of accessory sinuses	0.666	0.334
C30 Malignant neoplasm of nasal cavity and middle ear	0.666	0.334
C37 Malignant neoplasm of thymus	0.666	0.334
C33 Malignant neoplasm of trachea	0.666	0.334
K77 Liver disorders in diseases classified elsewhere	0.665	0.335
K73 Chronic hepatitis, not elsewhere classified	0.665	0.335
K71 Toxic liver disease	0.665	0.335
O66 Other obstructed labour	0.665	0.335
K40-K46 Hernia	0.665	0.335
M20.6 Acquired deformity of toe(s), unspecified	0.665	0.335
E87.0 Hyperosmolality and hypernatraemia	0.665	0.335
S22.40 Multiple fractures of ribs (closed)	0.665	0.335
O81 Single delivery by forceps and vacuum extractor	0.664	0.335
E13 Other specified diabetes mellitus	0.664	0.336
E83 Disorders of mineral metabolism	0.664	0.336
M54.1 Radiculopathy	0.663	0.336
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.663	0.337
S01.7 Multiple open wounds of head	0.663	0.337
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.663	0.337
M65.9 Synovitis and tenosynovitis, unspecified	0.663	0.337
G99 Other disorders of nervous system in diseases classified elsewhere	0.661	0.339
K91.4 Colostomy and enterostomy malfunction	0.660	0.340
M24.4 Recurrent dislocation and subluxation of joint	0.659	0.341
C68 Malignant neoplasm of other and unspecified urinary organs	0.659	0.341
C66 Malignant neoplasm of ureter	0.659	0.341
D80-D89 Certain disorders involving the immune mechanism	0.659	0.341
A50-A64 Infections with a predominantly sexual mode of transmission	0.657	0.343
M35.7 Hypermobility syndrome	0.657	0.343
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status	0.657	0.343
H46-H48 Disorders of optic nerve and visual pathways	0.657	0.343
D68.9 Coagulation defect, unspecified	0.657	0.343
K52.3 Indeterminate colitis	0.655	0.345
K52.2 Allergic and dietetic gastro-enteritis and colitis	0.655	0.345
K52.0 Gastro-enteritis and colitis due to radiation	0.655	0.345
H55-H59 Other disorders of eye and adnexa	0.655	0.345
O08 Complications following abortion and ectopic and molar pregnancy	0.655	0.345
O07 Failed attempted abortion	0.655	0.345
O06 Unspecified abortion	0.655	0.345
O05 Other abortion	0.655	0.345
O01 Hydatidiform mole	0.655	0.345
M54.2 Cervicalgia	0.655	0.345
O70.1 Second degree perineal laceration during delivery	0.654	0.346
F42 Obsessive-compulsive disorder	0.653	0.347
M21.3 Wrist or foot drop (acquired)	0.653	0.347
K52.1 Toxic gastro-enteritis and colitis	0.652	0.348
T84.0 Mechanical complication of internal joint prosthesis	0.652	0.348
M47.26 Other spondylosis with radiculopathy (Lumbar region)	0.651	0.349
A80-A89 Viral infections of the central nervous system	0.650	0.350
S29 Other and unspecified injuries of thorax	0.650	0.350
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.650	0.350
S26 Injury of heart	0.650	0.350
S25 Injury of blood vessels of thorax	0.650	0.350
S24 Injury of nerves and spinal cord at thorax level	0.650	0.350
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.650	0.350
S21 Open wound of thorax	0.650	0.350
T92 Sequelae of injuries of upper limb	0.650	0.350
T86.1 Kidney transplant failure and rejection	0.650	0.350
Z93 Artificial opening status	0.649	0.351
M24.2 Disorder of ligament	0.649	0.351
C67.9 Bladder, unspecified	0.649	0.351
K86.0 Alcohol-induced chronic pancreatitis	0.647	0.353
C67.2 Lateral wall of bladder	0.647	0.353
T13 Other injuries of lower limb, level unspecified	0.647	0.353
Z87 Personal history of other diseases and conditions	0.647	0.353
M54.8 Other dorsalgia	0.646	0.354
M54.6 Pain in thoracic spine	0.646	0.354
M54.0 Panniculitis affecting regions of neck and back	0.646	0.354
B15-B19 Viral hepatitis	0.646	0.354
Z90 Acquired absence of organs, not elsewhere classified	0.646	0.354
K92.9 Disease of digestive system, unspecified	0.645	0.354
D67 Hereditary factor IX deficiency	0.645	0.355
D66 Hereditary factor VIII deficiency	0.645	0.355
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.645	0.355
H90-H95 Other disorders of ear	0.645	0.355
M20.2 Hallux rigidus	0.644	0.356
E53 Deficiency of other B group vitamins	0.644	0.356
E35 Disorders of endocrine glands in diseases classified elsewhere	0.644	0.356
E34 Other endocrine disorders	0.644	0.356
E32 Diseases of thymus	0.644	0.356
E31 Polyglandular dysfunction	0.644	0.356
E30 Disorders of puberty, not elsewhere classified	0.644	0.356
E26 Hyperaldosteronism	0.644	0.356
E25 Adrenogenital disorders	0.644	0.356
E24 Cushing's syndrome	0.644	0.356
E20 Hypoparathyroidism	0.644	0.356
O68 Labour and delivery complicated by foetal stress [distress]	0.644	0.356
K82.1 Hydrops of gallbladder	0.643	0.357
M51.3 Other specified intervertebral disk degeneration	0.643	0.357
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy	0.643	0.357
M51.9 Intervertebral disk disorder, unspecified	0.643	0.357
M51.4 Schmorl's nodes	0.643	0.357
E66.2 Extreme obesity with alveolar hypoventilation	0.643	0.357
E66.1 Drug-induced obesity	0.643	0.357
E66.0 Obesity due to excess calories	0.643	0.357
M25.6 Stiffness of joint, not elsewhere classified	0.642	0.358
M25.3 Other instability of joint	0.642	0.358
M25.2 Flail joint	0.642	0.358
M25.1 Fistula of joint	0.642	0.358
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.641	0.359
M54.59 Low back pain (Site unspecified)	0.641	0.359
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified	0.641	0.359
A09.9 Gastroenteritis and colitis of unspecified origin	0.641	0.359
F17.9 Unspecified mental and behavioural disorder	0.640	0.360
F17.8 Other mental and behavioural disorders	0.640	0.360
F17.7 Residual and late-onset psychotic disorder	0.640	0.360
F17.6 Amnesic syndrome	0.640	0.360
F17.5 Psychotic disorder	0.640	0.360
F17.4 Withdrawal state with delirium	0.640	0.360
F17.3 Withdrawal state	0.640	0.360
F17.0 Acute intoxication	0.640	0.360
G50-G59 Nerve, nerve root and plexus disorders	0.639	0.361
D52 Folate deficiency anaemia	0.639	0.361
M21.9 Acquired deformity of limb, unspecified	0.639	0.361
M21.8 Other specified acquired deformities of limbs	0.639	0.361
M21.7 Unequal limb length (acquired)	0.639	0.361
M21.6 Other acquired deformities of ankle and foot	0.639	0.361
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot	0.639	0.361
M21.4 Flat foot [pes planus] (acquired)	0.639	0.361
E27 Other disorders of adrenal gland	0.639	0.361
T85.2 Mechanical complication of intraocular lens	0.638	0.362
F48 Other neurotic disorders	0.638	0.362
F44 Dissociative [conversion] disorders	0.638	0.362
B99-B99 Other infectious diseases	0.638	0.362
B85-B89 Pediculosis, acariasis and other infestations	0.638	0.362
B65-B83 Helminthiases	0.638	0.362
B50-B64 Protozoal diseases	0.638	0.362
B20-B24 Human immunodeficiency virus [HIV] disease	0.638	0.362
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.638	0.362
A75-A79 Rickettsioses	0.638	0.362
A70-A74 Other diseases caused by chlamydiae	0.638	0.362
A65-A69 Other spirochaetal diseases	0.638	0.362
A20-A28 Certain zoonotic bacterial diseases	0.638	0.362
A15-A19 Tuberculosis	0.638	0.362
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.637	0.363
T90 Sequelae of injuries of head	0.635	0.365
S42 Fracture of shoulder and upper arm	0.635	0.365
M50.9 Cervical disk disorder, unspecified	0.635	0.365
M50.8 Other cervical disk disorders	0.635	0.365
T85.4 Mechanical complication of breast prosthesis and implant	0.634	0.366
K86.8 Other specified diseases of pancreas	0.634	0.366
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.633	0.367
D68.5 Primary Thrombophilia	0.633	0.367
M68 Disorders of synovium and tendon in diseases classified elsewhere	0.632	0.367
M66 Spontaneous rupture of synovium and tendon	0.632	0.367
Z87.1 Personal history of diseases of the digestive system	0.632	0.368
F10.2 Dependence syndrome	0.632	0.368

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations