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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs114752366
log Bayes Factor = 15.9284
Chromosome 5   position 20,126,254  (GRCh37) Explore rs114752366 on Ensembl!
Variant rs114752366 is part of Cluster X0100

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
M20-M25 Other joint disorders
1.000 0.000 0.000
Chapter XV Pregnancy, childbirth and the puerperium
1.000 0.000 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.999 0.001 0.000
Chapter II Neoplasms
0.999 0.001 0.000
M20 Acquired deformities of fingers and toes
0.998 0.002 0.000
M50-M54 Other dorsopathies
0.998 0.002 0.000
C79 Secondary malignant neoplasm of other sites
0.997 0.003 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.996 0.004 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.996 0.004 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.991 0.009 0.000
Chapter X Diseases of the respiratory system
0.988 0.012 0.000
O60-O75 Complications of labour and delivery
0.988 0.012 0.000
J09-J18 Influenza and pneumonia
0.984 0.016 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.982 0.018 0.000
M20.1 Hallux valgus (acquired)
0.976 0.024 0.000
J18 Pneumonia, organism unspecified
0.975 0.025 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.975 0.025 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.973 0.027 0.000
M50 Cervical disk disorders
0.971 0.029 0.000
O00-O08 Pregnancy with abortive outcome
0.970 0.030 0.000
Chapter V Mental and behavioural disorders
0.967 0.033 0.000
M20.4 Other hammer toe(s) (acquired)
0.963 0.037 0.000
M54 Dorsalgia
0.962 0.038 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.954 0.046 0.000
D69 Purpura and other haemorrhagic conditions
0.951 0.049 0.000
M25 Other joint disorders, not elsewhere classified
0.949 0.051 0.000
J18.9 Pneumonia, unspecified
0.948 0.052 0.000
M20.5 Other deformities of toe(s) (acquired)
0.946 0.054 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.937 0.063 0.000
J18.1 Lobar pneumonia, unspecified
0.935 0.065 0.000
E20-E35 Disorders of other endocrine glands
0.932 0.068 0.000
D69.6 Thrombocytopenia, unspecified
0.931 0.069 0.000
M45-M49 Spondylopathies
0.931 0.069 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.924 0.076 0.000
O03 Spontaneous abortion
0.921 0.079 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.920 0.080 0.000
Chapter XI Diseases of the digestive system
0.918 0.082 0.000
J90-J94 Other diseases of pleura
0.917 0.083 0.000
Chapter XX External causes of morbidity and mortality
0.916 0.084 0.000
M54.5 Low back pain
0.915 0.085 0.000
S80-S89 Injuries to the knee and lower leg
0.907 0.093 0.000
O02 Other abnormal products of conception
0.900 0.100 0.000
O70 Perineal laceration during delivery
0.898 0.102 0.000
M51 Other intervertebral disk disorders
0.896 0.104 0.000
M21 Other acquired deformities of limbs
0.895 0.105 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.893 0.107 0.000
M50.0 Cervical disk disorder with myelopathy
0.893 0.107 0.000
O72 Postpartum haemorrhage
0.891 0.109 0.000
C78.2 Secondary malignant neoplasm of pleura
0.891 0.109 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.887 0.113 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.886 0.114 0.000
K90-K93 Other diseases of the digestive system
0.883 0.117 0.000
E65-E68 Obesity and other hyperalimentation
0.882 0.118 0.000
K70-K77 Diseases of liver
0.881 0.119 0.000
J90 Pleural effusion, not elsewhere classified
0.881 0.119 0.000
C78.0 Secondary malignant neoplasm of lung
0.880 0.120 0.000
C34 Malignant neoplasm of bronchus and lung
0.878 0.122 0.000
M50.1 Cervical disk disorder with radiculopathy
0.877 0.123 0.000
M25.7 Osteophyte
0.871 0.129 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.866 0.134 0.000
K92 Other diseases of digestive system
0.865 0.135 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.863 0.137 0.000
M65-M68 Disorders of synovium and tendon
0.862 0.138 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.860 0.140 0.000
D50-D53 Nutritional anaemias
0.859 0.141 0.000
O03.4 Incomplete, without complication
0.857 0.143 0.000
Chapter I Certain infectious and parasitic diseases
0.857 0.143 0.000
M47 Spondylosis
0.857 0.143 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.856 0.144 0.000
S20-S29 Injuries to the thorax
0.853 0.147 0.000
M24 Other specific joint derangements
0.853 0.147 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.852 0.148 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.850 0.150 0.000
O02.1 Missed abortion
0.849 0.151 0.000
O70.1 Second degree perineal laceration during delivery
0.848 0.152 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.847 0.153 0.000
O80-O84 Delivery
0.845 0.155 0.000
O63 Long labour
0.844 0.156 0.000
K50-K52 Noninfective enteritis and colitis
0.843 0.157 0.000
C78.7 Secondary malignant neoplasm of liver
0.840 0.160 0.000
F41 Other anxiety disorders
0.839 0.161 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.838 0.162 0.000
D68 Other coagulation defects
0.838 0.162 0.000
E70-E90 Metabolic disorders
0.835 0.165 0.000
M54.9 Dorsalgia, unspecified
0.835 0.165 0.000
Chapter VI Diseases of the nervous system
0.834 0.166 0.000
K92.1 Melaena
0.830 0.170 0.000
E50-E64 Other nutritional deficiencies
0.826 0.174 0.000
M31 Other necrotising vasculopathies
0.822 0.178 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.821 0.179 0.000
C79.6 Secondary malignant neoplasm of ovary
0.821 0.179 0.000
J60-J70 Lung diseases due to external agents
0.816 0.183 0.000
M50.3 Other cervical disk degeneration
0.815 0.185 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.814 0.186 0.000
M22 Disorders of patella
0.814 0.186 0.000
M40-M43 Deforming dorsopathies
0.811 0.189 0.000
E66 Obesity
0.810 0.190 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.810 0.190 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.809 0.191 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.809 0.191 0.000
E22 Hyperfunction of pituitary gland
0.809 0.191 0.000
S70-S79 Injuries to the hip and thigh
0.808 0.192 0.000
M25.77 Osteophyte (Ankle and foot)
0.806 0.194 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.805 0.195 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.802 0.198 0.000
T86 Failure and rejection of transplanted organs and tissues
0.801 0.199 0.000
C79.2 Secondary malignant neoplasm of skin
0.801 0.199 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.801 0.199 0.000
S40-S49 Injuries to the shoulder and upper arm
0.800 0.200 0.000
F40 Phobic anxiety disorders
0.797 0.203 0.000
K76 Other diseases of liver
0.796 0.204 0.000
M54.59 Low back pain (Site unspecified)
0.793 0.207 0.000
F17.2 Dependence syndrome
0.792 0.208 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.792 0.208 0.000
C34.9 Bronchus or lung, unspecified
0.791 0.209 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.789 0.211 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.789 0.211 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.786 0.214 0.000
M20.3 Other deformity of hallux (acquired)
0.785 0.215 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.784 0.216 0.000
O70.2 Third degree perineal laceration during delivery
0.783 0.217 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.783 0.217 0.000
M51.2 Other specified intervertebral disk displacement
0.782 0.218 0.000
M54.56 Low back pain (Lumbar region)
0.782 0.218 0.000
K52 Other non-infective gastro-enteritis and colitis
0.782 0.218 0.000
M25.0 Haemarthrosis
0.781 0.219 0.000
O72.1 Other immediate postpartum haemorrhage
0.780 0.220 0.000
K76.0 Fatty (change of) liver, not elsewhere classified
0.779 0.221 0.000
O03.9 Complete or unspecified, without complication
0.778 0.222 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.776 0.224 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.776 0.224 0.000
M54.57 Low back pain (Lumbosacral region)
0.775 0.225 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.773 0.227 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.773 0.227 0.000
E66.9 Obesity, unspecified
0.773 0.227 0.000
M54.99 Dorsalgia, unspecified (Site unspecified)
0.772 0.228 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.769 0.230 0.000
K92.0 Haematemesis
0.769 0.231 0.000
S00-S09 Injuries to the head
0.769 0.231 0.000
M25.8 Other specified joint disorders
0.769 0.231 0.000
Chapter VIII Diseases of the ear and mastoid process
0.767 0.233 0.000
K86 Other diseases of pancreas
0.767 0.233 0.000
M48 Other spondylopathies
0.767 0.233 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.767 0.233 0.000
E40-E46 Malnutrition
0.766 0.234 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.765 0.235 0.000
O62 Abnormalities of forces of labour
0.764 0.236 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.760 0.240 0.000
S81 Open wound of lower leg
0.759 0.241 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.755 0.245 0.000
D00-D09 In situ neoplasms
0.755 0.245 0.000
F41.9 Anxiety disorder, unspecified
0.753 0.247 0.000
E28 Ovarian dysfunction
0.752 0.248 0.000
X60-X84 Intentional self-harm
0.752 0.248 0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts
0.752 0.248 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.751 0.249 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.749 0.251 0.000
M47.2 Other spondylosis with radiculopathy
0.749 0.251 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.748 0.252 0.000
G90-G99 Other disorders of the nervous system
0.748 0.252 0.000
K75 Other inflammatory liver diseases
0.746 0.254 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.745 0.254 0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria
0.745 0.255 0.000
C64-C68 Malignant neoplasms of urinary tract
0.744 0.256 0.000
E86 Volume depletion
0.744 0.256 0.000
M35 Other systemic involvement of connective tissue
0.743 0.257 0.000
M25.4 Effusion of joint
0.743 0.257 0.000
J14 Pneumonia due to Haemophilus influenzae
0.741 0.259 0.000
J00-J06 Acute upper respiratory infections
0.741 0.259 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.740 0.259 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.740 0.260 0.000
O81 Single delivery by forceps and vacuum extractor
0.739 0.261 0.000
G35 Multiple sclerosis
0.737 0.263 0.000
M47.9 Spondylosis, unspecified
0.737 0.263 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.736 0.264 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.736 0.264 0.000
C32 Malignant neoplasm of larynx
0.736 0.264 0.000
E21.0 Primary hyperparathyroidism
0.736 0.264 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.735 0.265 0.000
M80-M85 Disorders of bone density and structure
0.734 0.265 0.000
M67 Other disorders of synovium and tendon
0.734 0.266 0.000
T83.0 Mechanical complication of urinary (indwelling) catheter
0.734 0.266 0.000
O72.2 Delayed and secondary postpartum haemorrhage
0.733 0.267 0.000
D60-D64 Aplastic and other anaemias
0.732 0.268 0.000
M21.0 Valgus deformity, not elsewhere classified
0.732 0.268 0.000
O47 False labour
0.731 0.269 0.000
A30-A49 Other bacterial diseases
0.730 0.270 0.000
A00-A09 Intestinal infectious diseases
0.729 0.271 0.000
F43 Reaction to severe stress, and adjustment disorders
0.728 0.272 0.000
M91-M94 Chondropathies
0.727 0.273 0.000
O48 Prolonged pregnancy
0.727 0.273 0.000
E53 Deficiency of other B group vitamins
0.726 0.273 0.000
M54.1 Radiculopathy
0.725 0.275 0.000
Chapter XXII Codes for special purposes
0.724 0.276 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.722 0.278 0.000
S90-S99 Injuries to the ankle and foot
0.720 0.280 0.000
O82 Single delivery by Caesarean section
0.719 0.281 0.000
D69.3 Idiopathic thrombocytopenic purpura
0.718 0.282 0.000
T79-T79 Certain early complications of trauma
0.717 0.283 0.000
T66-T78 Other and unspecified effects of external causes
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.717 0.283 0.000
M34 Systemic sclerosis
0.717 0.283 0.000
M33 Dermatopolymyositis
0.717 0.283 0.000
M32 Systemic lupus erythematosus
0.717 0.283 0.000
M30 Polyarteritis nodosa and related conditions
0.717 0.283 0.000
O85-O92 Complications predominantly related to the puerperium
0.717 0.283 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.717 0.283 0.000
M54.2 Cervicalgia
0.716 0.283 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.716 0.284 0.000
M25.3 Other instability of joint
0.716 0.284 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.716 0.284 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.716 0.284 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.716 0.284 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.714 0.285 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.714 0.285 0.000
T33-T35 Frostbite
0.714 0.286 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.714 0.286 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.714 0.286 0.000
T00-T07 Injuries involving multiple body regions
0.714 0.286 0.000
S10-S19 Injuries to the neck
0.714 0.286 0.000
O42 Premature rupture of membranes
0.714 0.286 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.714 0.286 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.714 0.286 0.000
K82 Other diseases of gallbladder
0.714 0.286 0.000
M21.3 Wrist or foot drop (acquired)
0.713 0.287 0.000
Q60-Q64 Congenital malformations of the urinary system
0.712 0.288 0.000
M53 Other dorsopathies, not elsewhere classified
0.712 0.288 0.000
D52 Folate deficiency anaemia
0.711 0.289 0.000
M25.9 Joint disorder, unspecified
0.711 0.289 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.711 0.289 0.000
D55-D59 Haemolytic anaemias
0.710 0.289 0.000
S89 Other and unspecified injuries of lower leg
0.710 0.290 0.000
K52.9 Non-infective gastro-enteritis and colitis, unspecified
0.709 0.291 0.000
M25.76 Osteophyte (Lower leg)
0.708 0.292 0.000
O74 Complications of anaesthesia during labour and delivery
0.708 0.292 0.000
O73 Retained placenta and membranes, without haemorrhage
0.708 0.292 0.000
O71 Other obstetric trauma
0.708 0.292 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.708 0.292 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.708 0.292 0.000
O61 Failed induction of labour
0.708 0.292 0.000
O60 Preterm delivery
0.708 0.292 0.000
K72 Hepatic failure, not elsewhere classified
0.708 0.292 0.000
J95-J99 Other diseases of the respiratory system
0.706 0.294 0.000
M86-M90 Other osteopathies
0.706 0.294 0.000
F40.2 Specific (isolated) phobias
0.706 0.294 0.000
J17 Pneumonia in diseases classified elsewhere
0.705 0.295 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.705 0.295 0.000
J12 Viral pneumonia, not elsewhere classified
0.705 0.295 0.000
J11 Influenza, virus not identified
0.705 0.295 0.000
J10 Influenza due to identified influenza virus
0.705 0.295 0.000
J09 Influenza due to certain identified influenza virus
0.705 0.295 0.000
K50 Crohn's disease [regional enteritis]
0.705 0.295 0.000
X50-X57 Overexertion, travel and privation
0.703 0.297 0.000
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid
0.703 0.297 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.702 0.298 0.000
M05-M14 Inflammatory polyarthropathies
0.702 0.298 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.701 0.299 0.000
M21.4 Flat foot [pes planus] (acquired)
0.700 0.300 0.000
O68.1 Labour and delivery complicated by meconium in amniotic fluid
0.700 0.300 0.000
J18.8 Other pneumonia, organism unspecified
0.699 0.301 0.000
J18.2 Hypostatic pneumonia, unspecified
0.699 0.301 0.000
D67 Hereditary factor IX deficiency
0.699 0.301 0.000
D66 Hereditary factor VIII deficiency
0.699 0.301 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.699 0.301 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.698 0.302 0.000
T87 Complications peculiar to reattachment and amputation
0.698 0.302 0.000
M50.9 Cervical disk disorder, unspecified
0.696 0.304 0.000
M50.8 Other cervical disk disorders
0.696 0.304 0.000
O08 Complications following abortion and ectopic and molar pregnancy
0.696 0.304 0.000
O07 Failed attempted abortion
0.696 0.304 0.000
O06 Unspecified abortion
0.696 0.304 0.000
O05 Other abortion
0.696 0.304 0.000
O01 Hydatidiform mole
0.696 0.304 0.000
J94 Other pleural conditions
0.696 0.304 0.000
M46 Other inflammatory spondylopathies
0.695 0.304 0.000
J61 Pneumoconiosis due to asbestos and other mineral fibres
0.695 0.305 0.000
M31.6 Other giant cell arteritis
0.694 0.306 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.693 0.307 0.000
F99-F99 Unspecified mental disorder
0.693 0.307 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.693 0.307 0.000
F70-F79 Mental retardation
0.693 0.307 0.000
F60-F69 Disorders of adult personality and behaviour
0.693 0.307 0.000
M51.8 Other specified intervertebral disk disorders
0.693 0.307 0.000
C34.1 Upper lobe, bronchus or lung
0.693 0.307 0.000
C34.0 Main bronchus
0.693 0.307 0.000
O63.1 Prolonged second stage (of labour)
0.693 0.307 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.692 0.308 0.000
Chapter VII Diseases of the eye and adnexa
0.691 0.309 0.000
O66 Other obstructed labour
0.690 0.309 0.000
J03 Acute tonsillitis
0.690 0.310 0.000
M47.96 Spondylosis, unspecified (Lumbar region)
0.690 0.310 0.000
M54.8 Other dorsalgia
0.690 0.310 0.000
M54.6 Pain in thoracic spine
0.690 0.310 0.000
M54.0 Panniculitis affecting regions of neck and back
0.690 0.310 0.000
W50-W64 Exposure to animate mechanical forces
0.690 0.310 0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy
0.689 0.310 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.689 0.311 0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension
0.686 0.314 0.000
E27 Other disorders of adrenal gland
0.684 0.316 0.000
M21.1 Varus deformity, not elsewhere classified
0.683 0.316 0.000
E88 Other metabolic disorders
0.683 0.317 0.000
E23 Hypofunction and other disorders of pituitary gland
0.683 0.317 0.000
O63.9 Long labour, unspecified
0.683 0.317 0.000
D69.9 Haemorrhagic condition, unspecified
0.682 0.318 0.000
D69.8 Other specified haemorrhagic conditions
0.682 0.318 0.000
D69.5 Secondary thrombocytopenia
0.682 0.318 0.000
D69.4 Other primary thrombocytopenia
0.682 0.318 0.000
D69.2 Other nonthrombocytopenic purpura
0.682 0.318 0.000
D69.1 Qualitative platelet defects
0.682 0.318 0.000
D69.0 Allergic purpura
0.682 0.318 0.000
K70 Alcoholic liver disease
0.681 0.319 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.681 0.319 0.000
M25.2 Flail joint
0.681 0.319 0.000
M25.1 Fistula of joint
0.681 0.319 0.000
M43 Other deforming dorsopathies
0.680 0.320 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.680 0.320 0.000
F42 Obsessive-compulsive disorder
0.678 0.322 0.000
M54.4 Lumbago with sciatica
0.678 0.322 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.677 0.323 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.677 0.323 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.676 0.324 0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis
0.676 0.324 0.000
D80-D89 Certain disorders involving the immune mechanism
0.674 0.326 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.674 0.326 0.000
S82 Fracture of lower leg, including ankle
0.673 0.327 0.000
M65 Synovitis and tenosynovitis
0.673 0.327 0.000
F80-F89 Disorders of psychological development
0.673 0.327 0.000
D51 Vitamin B12 deficiency anaemia
0.673 0.327 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.672 0.328 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.672 0.328 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.672 0.328 0.000
C31 Malignant neoplasm of accessory sinuses
0.672 0.328 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.672 0.328 0.000
C37 Malignant neoplasm of thymus
0.672 0.328 0.000
C33 Malignant neoplasm of trachea
0.672 0.328 0.000
M47.26 Other spondylosis with radiculopathy (Lumbar region)
0.672 0.328 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.671 0.329 0.000
O43 Placental disorders
0.669 0.331 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.668 0.332 0.000
E34 Other endocrine disorders
0.668 0.332 0.000
E32 Diseases of thymus
0.668 0.332 0.000
E31 Polyglandular dysfunction
0.668 0.332 0.000
E30 Disorders of puberty, not elsewhere classified
0.668 0.332 0.000
E29 Testicular dysfunction
0.668 0.332 0.000
E26 Hyperaldosteronism
0.668 0.332 0.000
E25 Adrenogenital disorders
0.668 0.332 0.000
E24 Cushing's syndrome
0.668 0.332 0.000
E20 Hypoparathyroidism
0.668 0.332 0.000
S81.0 Open wound of knee
0.668 0.332 0.000
M49 Spondylopathies in diseases classified elsewhere
0.667 0.332 0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants
0.667 0.333 0.000
T83.3 Mechanical complication of intra-uterine contraceptive device
0.667 0.333 0.000
J91 Pleural effusion in conditions classified elsewhere
0.667 0.333 0.000
K85 Acute pancreatitis
0.667 0.333 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.666 0.334 0.000
T86.1 Kidney transplant failure and rejection
0.666 0.334 0.000
M24.1 Other articular cartilage disorders
0.666 0.334 0.000
S27 Injury of other and unspecified intrathoracic organs
0.665 0.335 0.000
E83 Disorders of mineral metabolism
0.664 0.336 0.000
O81.4 Vacuum extractor delivery
0.663 0.337 0.000
K52.8 Other specified non-infective gastro-enteritis and colitis
0.662 0.337 0.000
F48 Other neurotic disorders
0.662 0.338 0.000
F44 Dissociative [conversion] disorders
0.662 0.338 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.662 0.338 0.000
C34.3 Lower lobe, bronchus or lung
0.662 0.338 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.662 0.338 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.661 0.339 0.000
O03.8 Complete or unspecified, with other and unspecified complications
0.660 0.339 0.000
O03.7 Complete or unspecified, complicated by embolism
0.660 0.339 0.000
O03.6 Complete or unspecified, complicated by delayed or excessive haemorrhage
0.660 0.339 0.000
O03.5 Complete or unspecified, complicated by genital tract and pelvic infection
0.660 0.339 0.000
O03.3 Incomplete, with other and unspecified complications
0.660 0.339 0.000
O03.2 Incomplete, complicated by embolism
0.660 0.339 0.000
O03.1 Incomplete, complicated by delayed or excessive haemorrhage
0.660 0.339 0.000
O03.0 Incomplete, complicated by genital tract and pelvic infection
0.660 0.339 0.000
M25.06 Haemarthrosis (Lower leg)
0.660 0.340 0.000
Y43 Primarily systemic agents
0.660 0.340 0.000
F41.0 Panic disorder [episodic paroxysmal anxiety]
0.658 0.342 0.000
K86.3 Pseudocyst of pancreas
0.658 0.342 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.658 0.342 0.000
O40 Polyhydramnios
0.658 0.342 0.000
V80-V89 Other land transport accidents
0.658 0.342 0.000
K65-K67 Diseases of peritoneum
0.657 0.343 0.000
Y35-Y36 Legal intervention and operations of war
0.656 0.343 0.000
Y10-Y34 Event of undetermined intent
0.656 0.343 0.000
Y00-Y09 Assault
0.656 0.343 0.000
X85-X99 Assault
0.656 0.343 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.656 0.343 0.000
X30-X39 Exposure to forces of nature
0.656 0.343 0.000
X20-X29 Contact with venomous animals and plants
0.656 0.343 0.000
X10-X19 Contact with heat and hot substances
0.656 0.343 0.000
X00-X09 Exposure to smoke, fire and flames
0.656 0.343 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.656 0.343 0.000
W75-W84 Other accidental threats to breathing
0.656 0.343 0.000
W65-W74 Accidental drowning and submersion
0.656 0.343 0.000
V98-V99 Other and unspecified transport accidents
0.656 0.343 0.000
V95-V97 Air and space transport accidents
0.656 0.343 0.000
V90-V94 Water transport accidents
0.656 0.343 0.000
V70-V79 Bus occupant injured in transport accident
0.656 0.343 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.656 0.343 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.656 0.343 0.000
V40-V49 Car occupant injured in transport accident
0.656 0.343 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.656 0.343 0.000
V01-V09 Pedestrian injured in transport accident
0.656 0.343 0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.656 0.344 0.000
M54.55 Low back pain (Thoracolumbar region)
0.656 0.344 0.000
M54.54 Low back pain-Thoracic
0.656 0.344 0.000
M54.53 Low back pain-Cervicothoracic
0.656 0.344 0.000
M54.52 Low back pain-Cervical
0.656 0.344 0.000
M54.51 Low back pain-Occipit-atl-axl
0.656 0.344 0.000
M54.50 Low back pain (Multiple sites in spine)
0.656 0.344 0.000
Y42.5 Other oestrogens and progestogens
0.656 0.344 0.000
E53.8 Deficiency of other specified B group vitamins
0.655 0.345 0.000
D50 Iron deficiency anaemia
0.655 0.345 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.655 0.345 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.654 0.345 0.000
J03.9 Acute tonsillitis, unspecified
0.654 0.346 0.000
M22.2 Patellofemoral disorders
0.654 0.346 0.000
E22.1 Hyperprolactinaemia
0.652 0.348 0.000
S88 Traumatic amputation of lower leg
0.650 0.350 0.000
S87 Crushing injury of lower leg
0.650 0.350 0.000
S86 Injury of muscle and tendon at lower leg level
0.650 0.350 0.000
S85 Injury of blood vessels at lower leg level
0.650 0.350 0.000
S84 Injury of nerves at lower leg level
0.650 0.350 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.650 0.350 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.650 0.350 0.000
S70 Superficial injury of hip and thigh
0.649 0.351 0.000
S80 Superficial injury of lower leg
0.649 0.351 0.000
M24.2 Disorder of ligament
0.648 0.352 0.000
T81 Complications of procedures, not elsewhere classified
0.648 0.352 0.000
Y44 Agents primarily affecting blood constituents
0.648 0.352 0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified
0.647 0.353 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.646 0.354 0.000
O00 Ectopic pregnancy
0.645 0.354 0.000
O02.9 Abnormal product of conception, unspecified
0.645 0.355 0.000
O02.8 Other specified abnormal products of conception
0.645 0.355 0.000
O02.0 Blighted ovum and nonhydatidiform mole
0.645 0.355 0.000
D70 Agranulocytosis
0.645 0.355 0.000
S20 Superficial injury of thorax
0.644 0.356 0.000
O70.9 Perineal laceration during delivery, unspecified
0.644 0.356 0.000
O70.3 Fourth degree perineal laceration during delivery
0.644 0.356 0.000
K82.1 Hydrops of gallbladder
0.643 0.357 0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts
0.643 0.357 0.000
F45 Somatoform disorders
0.642 0.357 0.000
O72.0 Third-stage haemorrhage
0.642 0.357 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.642 0.358 0.000
M51.3 Other specified intervertebral disk degeneration
0.642 0.358 0.000
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy
0.642 0.358 0.000
M51.9 Intervertebral disk disorder, unspecified
0.642 0.358 0.000
M51.4 Schmorl's nodes
0.642 0.358 0.000
M21.9 Acquired deformity of limb, unspecified
0.642 0.358 0.000
M21.8 Other specified acquired deformities of limbs
0.642 0.358 0.000
M21.7 Unequal limb length (acquired)
0.642 0.358 0.000
M21.6 Other acquired deformities of ankle and foot
0.642 0.358 0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot
0.642 0.358 0.000
M21.2 Flexion deformity
0.642 0.358 0.000
C07 Malignant neoplasm of parotid gland
0.641 0.359 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.641 0.359 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.641 0.359 0.000
Q80-Q89 Other congenital malformations
0.641 0.359 0.000
Q35-Q37 Cleft lip and cleft palate
0.641 0.359 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.641 0.359 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.641 0.359 0.000
D68.9 Coagulation defect, unspecified
0.641 0.359 0.000
V20-V29 Motorcycle rider injured in transport accident
0.640 0.360 0.000
W00-W19 Falls
0.640 0.360 0.000
O72.3 Postpartum coagulation defects
0.639 0.361 0.000
Q50-Q56 Congenital malformations of genital organs
0.639 0.361 0.000
M25.71 Osteophyte (Shoulder region)
0.639 0.361 0.000
D68.5 Primary Thrombophilia
0.637 0.363 0.000
T85.2 Mechanical complication of intraocular lens
0.637 0.363 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.636 0.364 0.000
Y57 Other and unspecified drugs and medicaments
0.636 0.364 0.000
T92 Sequelae of injuries of upper limb
0.635 0.365 0.000
H90-H95 Other disorders of ear
0.635 0.365 0.000
T13 Other injuries of lower limb, level unspecified
0.635 0.365 0.000
B15-B19 Viral hepatitis
0.635 0.365 0.000
M20.6 Acquired deformity of toe(s), unspecified
0.634 0.366 0.000
Q00-Q07 Congenital malformations of the nervous system
0.634 0.366 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.633 0.367 0.000
T85.4 Mechanical complication of breast prosthesis and implant
0.633 0.367 0.000
E67 Other hyperalimentation
0.632 0.368 0.000
E68 Sequelae of hyperalimentation
0.632 0.368 0.000
E65 Localised adiposity
0.632 0.368 0.000
D68.2 Hereditary deficiency of other clotting factors
0.632 0.368 0.000
K77 Liver disorders in diseases classified elsewhere
0.632 0.368 0.000
K73 Chronic hepatitis, not elsewhere classified
0.632 0.368 0.000
K71 Toxic liver disease
0.632 0.368 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.632 0.368 0.000
M67.1 Other contracture of tendon (sheath)
0.631 0.369 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.631 0.369 0.000
C92 Myeloid leukaemia
0.630 0.370 0.000
C34.8 Overlapping lesion of bronchus and lung
0.630 0.370 0.000
C34.2 Middle lobe, bronchus or lung
0.630 0.370 0.000
M10 Gout
0.630 0.370 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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