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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs114786810
log Bayes Factor = 15.296
Chromosome 1   position 163,312,552  (GRCh37) Explore rs114786810 on Ensembl!
Variant rs114786810 is part of Cluster X0129

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter VII Diseases of the eye and adnexa
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
I25 Chronic ischaemic heart disease
1.000 0.000 0.000
Chapter VI Diseases of the nervous system
0.999 0.001 0.000
Chapter XI Diseases of the digestive system
0.998 0.002 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.996 0.004 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.995 0.005 0.000
K55-K64 Other diseases of intestines
0.993 0.007 0.000
E10-E14 Diabetes mellitus
0.992 0.008 0.000
I25.2 Old myocardial infarction
0.991 0.009 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.989 0.011 0.000
H43-H45 Disorders of vitreous body and globe
0.987 0.013 0.000
G40-G47 Episodic and paroxysmal disorders
0.987 0.013 0.000
H30-H36 Disorders of choroid and retina
0.984 0.016 0.000
E10 Insulin-dependent diabetes mellitus
0.981 0.019 0.000
K62 Other diseases of anus and rectum
0.981 0.019 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.980 0.020 0.000
K63 Other diseases of intestine
0.975 0.025 0.000
K63.5 Polyp of colon
0.972 0.028 0.000
H43 Disorders of vitreous body
0.965 0.035 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.962 0.038 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.962 0.038 0.000
D60-D64 Aplastic and other anaemias
0.958 0.042 0.000
H25-H28 Disorders of lens
0.957 0.043 0.000
E10.9 Without complications
0.956 0.044 0.000
G43 Migraine
0.953 0.047 0.000
Chapter XX External causes of morbidity and mortality
0.948 0.052 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.947 0.053 0.000
D50-D53 Nutritional anaemias
0.940 0.060 0.000
K62.5 Haemorrhage of anus and rectum
0.939 0.061 0.000
E11 Non-insulin-dependent diabetes mellitus
0.932 0.068 0.000
H33 Retinal detachments and breaks
0.931 0.069 0.000
I84 Haemorrhoids
0.930 0.070 0.000
G43.9 Migraine, unspecified
0.926 0.074 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.924 0.076 0.000
M45-M49 Spondylopathies
0.924 0.076 0.000
I60-I69 Cerebrovascular diseases
0.920 0.080 0.000
K62.1 Rectal polyp
0.920 0.080 0.000
H26 Other cataract
0.920 0.080 0.000
M70-M79 Other soft tissue disorders
0.912 0.088 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.910 0.090 0.000
D64 Other anaemias
0.907 0.093 0.000
H36 Retinal disorders in diseases classified elsewhere
0.906 0.094 0.000
H43.8 Other disorders of vitreous body
0.906 0.094 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.905 0.095 0.000
K58 Irritable bowel syndrome
0.902 0.098 0.000
E20-E35 Disorders of other endocrine glands
0.902 0.098 0.000
H43.1 Vitreous haemorrhage
0.898 0.102 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.897 0.103 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.890 0.110 0.000
H33.3 Retinal breaks without detachment
0.887 0.113 0.000
I21 Acute myocardial infarction
0.883 0.117 0.000
D50 Iron deficiency anaemia
0.883 0.117 0.000
K20-K31 Diseases of oesophagus, stomach and duodenum
0.882 0.118 0.000
M05-M14 Inflammatory polyarthropathies
0.880 0.120 0.000
H44 Disorders of globe
0.875 0.125 0.000
H02 Other disorders of eyelid
0.872 0.128 0.000
D64.9 Anaemia, unspecified
0.870 0.130 0.000
K50-K52 Noninfective enteritis and colitis
0.867 0.133 0.000
H26.9 Cataract, unspecified
0.867 0.133 0.000
D50.8 Other iron deficiency anaemias
0.867 0.133 0.000
K90-K93 Other diseases of the digestive system
0.859 0.141 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.859 0.141 0.000
R50-R69 General symptoms and signs
0.858 0.142 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.857 0.143 0.000
Chapter II Neoplasms
0.850 0.150 0.000
H36.0 Diabetic retinopathy
0.850 0.150 0.000
E11.4 With neurological complications
0.847 0.153 0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal
0.846 0.154 0.000
D10-D36 Benign neoplasms
0.846 0.154 0.000
K70-K77 Diseases of liver
0.844 0.156 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.839 0.161 0.000
I67 Other cerebrovascular diseases
0.839 0.161 0.000
G20-G26 Extrapyramidal and movement disorders
0.835 0.165 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.835 0.165 0.000
I84.9 Unspecified haemorrhoids without complication
0.835 0.165 0.000
G30-G32 Other degenerative diseases of the nervous system
0.834 0.166 0.000
M06 Other rheumatoid arthritis
0.829 0.171 0.000
M47 Spondylosis
0.828 0.172 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.827 0.173 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.827 0.173 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.825 0.175 0.000
H27 Other disorders of lens
0.823 0.177 0.000
D12.5 Sigmoid colon
0.820 0.180 0.000
H26.4 After-cataract
0.818 0.182 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.816 0.184 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.816 0.184 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.815 0.185 0.000
E10.4 With neurological complications
0.815 0.185 0.000
G47 Sleep disorders
0.813 0.187 0.000
K92 Other diseases of digestive system
0.811 0.189 0.000
K58.0 Irritable bowel syndrome with diarrhoea
0.811 0.189 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.810 0.190 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.810 0.190 0.000
H55-H59 Other disorders of eye and adnexa
0.808 0.192 0.000
I84.2 Internal haemorrhoids without complication
0.808 0.192 0.000
E11.3 With ophthalmic complications
0.807 0.193 0.000
R51 Headache
0.806 0.194 0.000
K62.3 Rectal prolapse
0.806 0.194 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.806 0.194 0.000
M65-M68 Disorders of synovium and tendon
0.805 0.195 0.000
G35 Multiple sclerosis
0.802 0.198 0.000
R06 Abnormalities of breathing
0.802 0.198 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.799 0.201 0.000
H04 Disorders of lachrymal system
0.799 0.201 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.797 0.203 0.000
I24 Other acute ischaemic heart diseases
0.797 0.203 0.000
I84.8 Unspecified haemorrhoids with other complications
0.796 0.204 0.000
H33.0 Retinal detachment with retinal break
0.796 0.204 0.000
R06.5 Mouth breathing
0.795 0.205 0.000
H10-H13 Disorders of conjunctiva
0.792 0.208 0.000
Y44 Agents primarily affecting blood constituents
0.792 0.208 0.000
D12.2 Ascending colon
0.792 0.208 0.000
G63.2 Diabetic polyneuropathy
0.791 0.209 0.000
I80 Phlebitis and thrombophlebitis
0.790 0.210 0.000
E10.3 With ophthalmic complications
0.789 0.211 0.000
R56 Convulsions, not elsewhere classified
0.788 0.212 0.000
G81 Hemiplegia
0.787 0.213 0.000
M79.8 Other specified soft tissue disorders
0.786 0.214 0.000
M20-M25 Other joint disorders
0.781 0.219 0.000
M06.9 Rheumatoid arthritis, unspecified
0.780 0.220 0.000
H35 Other retinal disorders
0.779 0.221 0.000
M45 Ankylosing spondylitis
0.778 0.222 0.000
K62.9 Disease of anus and rectum, unspecified
0.778 0.222 0.000
I22 Subsequent myocardial infarction
0.776 0.224 0.000
D80-D89 Certain disorders involving the immune mechanism
0.775 0.225 0.000
H02.4 Ptosis of eyelid
0.773 0.227 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.772 0.228 0.000
K60 Fissure and fistula of anal and rectal regions
0.771 0.229 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.771 0.229 0.000
M47.8 Other spondylosis
0.770 0.230 0.000
G45.9 Transient cerebral ischaemic attack, unspecified
0.767 0.233 0.000
E10.1 With ketoacidosis
0.766 0.234 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.764 0.236 0.000
K62.8 Other specified diseases of anus and rectum
0.762 0.238 0.000
I25.1 Atherosclerotic heart disease
0.762 0.238 0.000
H53-H54 Visual disturbances and blindness
0.761 0.239 0.000
K26 Duodenal ulcer
0.760 0.240 0.000
Y43 Primarily systemic agents
0.760 0.240 0.000
I85 Oesophageal varices
0.759 0.241 0.000
I84.4 External haemorrhoids with other complications
0.757 0.243 0.000
K92.0 Haematemesis
0.756 0.244 0.000
D51 Vitamin B12 deficiency anaemia
0.755 0.244 0.000
Chapter XXII Codes for special purposes
0.752 0.248 0.000
V10-V19 Pedal cyclist injured in transport accident
0.751 0.248 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.750 0.250 0.000
K27 Peptic ulcer, site unspecified
0.750 0.250 0.000
H44.2 Degenerative myopia
0.749 0.251 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.748 0.251 0.000
H02.1 Ectropion of eyelid
0.746 0.254 0.000
H02.0 Entropion and trichiasis of eyelid
0.746 0.254 0.000
K72 Hepatic failure, not elsewhere classified
0.745 0.255 0.000
D12.7 Rectosigmoid junction
0.743 0.257 0.000
K50 Crohn's disease [regional enteritis]
0.743 0.257 0.000
I25.5 Ischaemic cardiomyopathy
0.742 0.258 0.000
Chapter XIV Diseases of the genitourinary system
0.739 0.261 0.000
G30 Alzheimer's disease
0.739 0.261 0.000
R56.8 Other and unspecified convulsions
0.738 0.262 0.000
M50-M54 Other dorsopathies
0.737 0.263 0.000
Y45.1 Salicylates
0.737 0.263 0.000
M79.86 Other specified soft tissue disorders (Lower leg)
0.736 0.264 0.000
Chapter VIII Diseases of the ear and mastoid process
0.736 0.264 0.000
G37 Other demyelinating diseases of central nervous system
0.736 0.264 0.000
D68 Other coagulation defects
0.735 0.265 0.000
E11.5 With peripheral circulatory complications
0.734 0.266 0.000
G40 Epilepsy
0.733 0.267 0.000
M46 Other inflammatory spondylopathies
0.732 0.268 0.000
Y40 Systemic antibiotics
0.731 0.269 0.000
K63.2 Fistula of intestine
0.730 0.270 0.000
D12.3 Transverse colon
0.730 0.270 0.000
H01 Other inflammation of eyelid
0.729 0.271 0.000
K92.1 Melaena
0.729 0.271 0.000
M91-M94 Chondropathies
0.728 0.272 0.000
G47.3 Sleep apnoea
0.728 0.272 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.727 0.273 0.000
I84.1 Internal haemorrhoids with other complications
0.724 0.276 0.000
K63.8 Other specified diseases of intestine
0.723 0.277 0.000
D35 Benign neoplasm of other and unspecified endocrine glands
0.721 0.279 0.000
R06.8 Other and unspecified abnormalities of breathing
0.721 0.279 0.000
K58.9 Irritable bowel syndrome without diarrhoea
0.720 0.280 0.000
K30 Dyspepsia
0.720 0.280 0.000
D62 Acute posthaemorrhagic anaemia
0.720 0.280 0.000
H02.6 Xanthelasma of eyelid
0.719 0.281 0.000
K65-K67 Diseases of peritoneum
0.719 0.281 0.000
R41.0 Disorientation, unspecified
0.719 0.281 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.718 0.282 0.000
G43.1 Migraine with aura [classical migraine]
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
I23 Certain current complications following acute myocardial infarction
0.717 0.283 0.000
I05-I09 Chronic rheumatic heart diseases
0.717 0.283 0.000
I25.6 Silent myocardial ischaemia
0.717 0.283 0.000
I25.4 Coronary artery aneurysm
0.717 0.283 0.000
I25.3 Aneurysm of heart
0.717 0.283 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.717 0.283 0.000
G70-G73 Diseases of myoneural junction and muscle
0.716 0.283 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.716 0.283 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.716 0.283 0.000
H44.0 Purulent endophthalmitis
0.716 0.284 0.000
I60 Subarachnoid haemorrhage
0.716 0.284 0.000
M80-M85 Disorders of bone density and structure
0.715 0.285 0.000
E23 Hypofunction and other disorders of pituitary gland
0.715 0.285 0.000
E40-E46 Malnutrition
0.714 0.286 0.000
D55-D59 Haemolytic anaemias
0.714 0.286 0.000
R68 Other general symptoms and signs
0.713 0.287 0.000
G81.9 Hemiplegia, unspecified
0.712 0.288 0.000
K64 Haemorrhoids and perianal venous thrombosis
0.712 0.288 0.000
G25 Other extrapyramidal and movement disorders
0.712 0.288 0.000
E13 Other specified diabetes mellitus
0.711 0.289 0.000
E12 Malnutrition-related diabetes mellitus
0.711 0.289 0.000
M47.82 Other spondylosis (Cervical region)
0.710 0.290 0.000
I62 Other nontraumatic intracranial haemorrhage
0.709 0.291 0.000
I20 Angina pectoris
0.709 0.291 0.000
M60-M63 Disorders of muscles
0.709 0.291 0.000
M00-M03 Infectious arthropathies
0.709 0.291 0.000
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.708 0.292 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.708 0.292 0.000
G44 Other headache syndromes
0.708 0.292 0.000
G41 Status epilepticus
0.708 0.292 0.000
M40-M43 Deforming dorsopathies
0.707 0.293 0.000
R53 Malaise and fatigue
0.706 0.294 0.000
I67.9 Cerebrovascular disease, unspecified
0.706 0.294 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.705 0.295 0.000
H31 Other disorders of choroid
0.705 0.295 0.000
H30 Chorioretinal inflammation
0.705 0.295 0.000
N17-N19 Renal failure
0.704 0.296 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.704 0.296 0.000
E14 Unspecified diabetes mellitus
0.704 0.296 0.000
E10.8 With unspecified complications
0.703 0.296 0.000
E10.7 With multiple complications
0.703 0.296 0.000
E10.6 With other specified complications
0.703 0.296 0.000
E10.5 With peripheral circulatory complications
0.703 0.296 0.000
E10.2 With renal complications
0.703 0.296 0.000
E10.0 With coma
0.703 0.296 0.000
I21.4 Acute subendocardial myocardial infarction
0.703 0.297 0.000
K62.2 Anal prolapse
0.703 0.297 0.000
W20-W49 Exposure to inanimate mechanical forces
0.703 0.297 0.000
K14 Diseases of tongue
0.703 0.297 0.000
K31 Other diseases of stomach and duodenum
0.702 0.298 0.000
M75 Shoulder lesions
0.700 0.300 0.000
K35-K38 Diseases of appendix
0.700 0.300 0.000
K63.4 Enteroptosis
0.699 0.301 0.000
K63.1 Perforation of intestine (nontraumatic)
0.699 0.301 0.000
K63.0 Abscess of intestine
0.699 0.301 0.000
K62.7 Radiation proctitis
0.699 0.301 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.699 0.301 0.000
D12.6 Colon, unspecified
0.698 0.302 0.000
M35 Other systemic involvement of connective tissue
0.697 0.303 0.000
Y44.2 Anticoagulants
0.697 0.303 0.000
I21.9 Acute myocardial infarction, unspecified
0.695 0.305 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.694 0.306 0.000
I67.1 Cerebral aneurysm, nonruptured
0.694 0.306 0.000
H43.9 Disorder of vitreous body, unspecified
0.692 0.308 0.000
H43.2 Crystalline deposits in vitreous body
0.692 0.308 0.000
H43.0 Vitreous prolapse
0.692 0.308 0.000
H27.8 Other specified disorders of lens
0.692 0.308 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.691 0.309 0.000
I88 Nonspecific lymphadenitis
0.690 0.310 0.000
I87 Other disorders of veins
0.690 0.310 0.000
I86 Varicose veins of other sites
0.690 0.310 0.000
I82 Other venous embolism and thrombosis
0.690 0.310 0.000
I81 Portal vein thrombosis
0.690 0.310 0.000
M86-M90 Other osteopathies
0.689 0.311 0.000
N18 Chronic renal failure
0.688 0.312 0.000
D61 Other aplastic anaemias
0.687 0.313 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.687 0.313 0.000
G80 Infantile cerebral palsy
0.686 0.314 0.000
D72 Other disorders of white blood cells
0.686 0.314 0.000
H28 Cataract and other disorders of lens in diseases classified elsewhere
0.686 0.314 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.686 0.314 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.684 0.316 0.000
G43.8 Other migraine
0.684 0.316 0.000
G43.3 Complicated migraine
0.684 0.316 0.000
G43.2 Status migrainosus
0.684 0.316 0.000
G43.0 Migraine without aura [common migraine]
0.684 0.316 0.000
K13 Other diseases of lip and oral mucosa
0.684 0.316 0.000
H18 Other disorders of cornea
0.683 0.317 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.681 0.319 0.000
H34 Retinal vascular occlusions
0.681 0.319 0.000
E50-E64 Other nutritional deficiencies
0.680 0.320 0.000
M79.0 Rheumatism, unspecified
0.680 0.320 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.680 0.320 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.680 0.320 0.000
Y35-Y36 Legal intervention and operations of war
0.680 0.320 0.000
Y10-Y34 Event of undetermined intent
0.680 0.320 0.000
Y00-Y09 Assault
0.680 0.320 0.000
X85-X99 Assault
0.680 0.320 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.680 0.320 0.000
X50-X57 Overexertion, travel and privation
0.680 0.320 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.680 0.320 0.000
X30-X39 Exposure to forces of nature
0.680 0.320 0.000
X20-X29 Contact with venomous animals and plants
0.680 0.320 0.000
X10-X19 Contact with heat and hot substances
0.680 0.320 0.000
X00-X09 Exposure to smoke, fire and flames
0.680 0.320 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.680 0.320 0.000
W75-W84 Other accidental threats to breathing
0.680 0.320 0.000
W65-W74 Accidental drowning and submersion
0.680 0.320 0.000
W50-W64 Exposure to animate mechanical forces
0.680 0.320 0.000
V98-V99 Other and unspecified transport accidents
0.680 0.320 0.000
V95-V97 Air and space transport accidents
0.680 0.320 0.000
V90-V94 Water transport accidents
0.680 0.320 0.000
V80-V89 Other land transport accidents
0.680 0.320 0.000
V70-V79 Bus occupant injured in transport accident
0.680 0.320 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.680 0.320 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.680 0.320 0.000
V40-V49 Car occupant injured in transport accident
0.680 0.320 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.680 0.320 0.000
V20-V29 Motorcycle rider injured in transport accident
0.680 0.320 0.000
V01-V09 Pedestrian injured in transport accident
0.680 0.320 0.000
D27 Benign neoplasm of ovary
0.680 0.320 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.679 0.321 0.000
H05 Disorders of orbit
0.679 0.321 0.000
H03 Disorders of eyelid in diseases classified elsewhere
0.679 0.321 0.000
K29 Gastritis and duodenitis
0.679 0.321 0.000
K60.1 Chronic anal fissure
0.679 0.321 0.000
E21.3 Hyperparathyroidism, unspecified
0.679 0.321 0.000
M65 Synovitis and tenosynovitis
0.678 0.321 0.000
E22 Hyperfunction of pituitary gland
0.674 0.326 0.000
K25 Gastric ulcer
0.674 0.326 0.000
M45.X9 Ankylosing spondylitis (Site unspecified)
0.674 0.326 0.000
N18.3 Chronic kidney disease, stage 3
0.674 0.326 0.000
D53 Other nutritional anaemias
0.674 0.326 0.000
D52 Folate deficiency anaemia
0.674 0.326 0.000
K51 Ulcerative colitis
0.674 0.326 0.000
X60-X84 Intentional self-harm
0.674 0.326 0.000
K72.9 Hepatic failure, unspecified
0.674 0.326 0.000
K62.6 Ulcer of anus and rectum
0.672 0.328 0.000
R59 Enlarged lymph nodes
0.671 0.329 0.000
R06.2 Wheezing
0.671 0.329 0.000
G30.9 Alzheimer's disease, unspecified
0.671 0.329 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.671 0.329 0.000
M75.4 Impingement syndrome of shoulder
0.671 0.329 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.670 0.330 0.000
M79.6 Pain in limb
0.669 0.331 0.000
E11.8 With unspecified complications
0.668 0.332 0.000
E11.7 With multiple complications
0.668 0.332 0.000
E11.6 With other specified complications
0.668 0.332 0.000
E11.2 With renal complications
0.668 0.332 0.000
E11.1 With ketoacidosis
0.668 0.332 0.000
E11.0 With coma
0.668 0.332 0.000
H33.5 Other retinal detachments
0.668 0.332 0.000
H33.4 Traction detachment of retina
0.668 0.332 0.000
H33.1 Retinoschisis and retinal cysts
0.668 0.332 0.000
I80.1 Phlebitis and thrombophlebitis of femoral vein
0.667 0.332 0.000
H43.3 Other vitreous opacities
0.667 0.333 0.000
I84.7 Unspecified thrombosed haemorrhoids
0.666 0.333 0.000
I84.0 Internal thrombosed haemorrhoids
0.666 0.333 0.000
K02 Dental caries
0.664 0.336 0.000
K26.9 Unspecified as acute or chronic, without haemorrhage or perforation
0.664 0.336 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.664 0.336 0.000
H20 Iridocyclitis
0.664 0.336 0.000
Y59 Other and unspecified vaccines and biological substances
0.662 0.338 0.000
Y58 Bacterial vaccines
0.662 0.338 0.000
Y57 Other and unspecified drugs and medicaments
0.662 0.338 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.662 0.338 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.662 0.338 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.662 0.338 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.662 0.338 0.000
Y52 Agents primarily affecting the cardiovascular system
0.662 0.338 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.662 0.338 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.662 0.338 0.000
Y48 Anaesthetics and therapeutic gases
0.662 0.338 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.662 0.338 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.662 0.338 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.662 0.338 0.000
M49 Spondylopathies in diseases classified elsewhere
0.662 0.338 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.662 0.338 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.662 0.338 0.000
I71 Aortic aneurysm and dissection
0.660 0.340 0.000
K22 Other diseases of oesophagus
0.660 0.340 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.660 0.340 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.660 0.340 0.000
H26.3 Drug-induced cataract
0.659 0.341 0.000
H26.2 Complicated cataract
0.659 0.341 0.000
H26.1 Traumatic cataract
0.659 0.341 0.000
H26.0 Infantile, juvenile and presenile cataract
0.659 0.341 0.000
E21.0 Primary hyperparathyroidism
0.659 0.341 0.000
I84.3 External thrombosed haemorrhoids
0.659 0.341 0.000
H04.1 Other disorders of lachrymal gland
0.659 0.341 0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.658 0.341 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.657 0.343 0.000
M06.0 Seronegative rheumatoid arthritis
0.657 0.343 0.000
I67.8 Other specified cerebrovascular diseases
0.656 0.344 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.656 0.344 0.000
G83 Other paralytic syndromes
0.656 0.344 0.000
K27.9 Unspecified as acute or chronic, without haemorrhage or perforation
0.655 0.345 0.000
M76 Enthesopathies of lower limb, excluding foot
0.654 0.346 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.654 0.346 0.000
M71 Other bursopathies
0.654 0.346 0.000
H35.4 Peripheral retinal degeneration
0.653 0.347 0.000
K62.4 Stenosis of anus and rectum
0.652 0.348 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.652 0.348 0.000
H27.0 Aphakia
0.652 0.348 0.000
D63.8 Anaemia in other chronic diseases classified elsewhere
0.651 0.349 0.000
K74 Fibrosis and cirrhosis of liver
0.650 0.350 0.000
D64.8 Other specified anaemias
0.650 0.350 0.000
D64.4 Congenital dyserythropoietic anaemia
0.650 0.350 0.000
D64.3 Other sideroblastic anaemias
0.650 0.350 0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.650 0.350 0.000
D64.1 Secondary sideroblastic anaemia due to disease
0.650 0.350 0.000
D64.0 Hereditary sideroblastic anaemia
0.650 0.350 0.000
H36.8 Other retinal disorders in diseases classified elsewhere
0.649 0.351 0.000
G36 Other acute disseminated demyelination
0.649 0.351 0.000
D12.4 Descending colon
0.648 0.352 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.646 0.353 0.000
E34 Other endocrine disorders
0.646 0.353 0.000
E32 Diseases of thymus
0.646 0.353 0.000
E31 Polyglandular dysfunction
0.646 0.353 0.000
E30 Disorders of puberty, not elsewhere classified
0.646 0.353 0.000
E29 Testicular dysfunction
0.646 0.353 0.000
E28 Ovarian dysfunction
0.646 0.353 0.000
E27 Other disorders of adrenal gland
0.646 0.353 0.000
E26 Hyperaldosteronism
0.646 0.353 0.000
E25 Adrenogenital disorders
0.646 0.353 0.000
E24 Cushing's syndrome
0.646 0.353 0.000
E20 Hypoparathyroidism
0.646 0.353 0.000
H00 Hordeolum and chalazion
0.646 0.354 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.645 0.355 0.000
N20-N23 Urolithiasis
0.645 0.355 0.000
I74 Arterial embolism and thrombosis
0.644 0.356 0.000
H11 Other disorders of conjunctiva
0.644 0.356 0.000
R60 Oedema, not elsewhere classified
0.644 0.356 0.000
G61 Inflammatory polyneuropathy
0.643 0.356 0.000
K31.7 Polyp of stomach and duodenum
0.643 0.356 0.000
G60 Hereditary and idiopathic neuropathy
0.643 0.357 0.000
G64 Other disorders of peripheral nervous system
0.643 0.357 0.000
Y43.3 Other antineoplastic drugs
0.643 0.357 0.000
E00-E07 Disorders of thyroid gland
0.642 0.358 0.000
H55 Nystagmus and other irregular eye movements
0.642 0.358 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.641 0.358 0.000
D72.8 Other specified disorders of white blood cells
0.641 0.359 0.000
M77 Other enthesopathies
0.641 0.359 0.000
D32 Benign neoplasm of meninges
0.639 0.360 0.000
G82 Paraplegia and tetraplegia
0.638 0.362 0.000
K75 Other inflammatory liver diseases
0.637 0.363 0.000
D11 Benign neoplasm of major salivary glands
0.636 0.364 0.000
M35.3 Polymyalgia rheumatica
0.634 0.366 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.634 0.366 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.633 0.367 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.633 0.367 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.633 0.367 0.000
D50.1 Sideropenic dysphagia
0.633 0.367 0.000
K52 Other non-infective gastro-enteritis and colitis
0.633 0.367 0.000
K28 Gastrojejunal ulcer
0.632 0.368 0.000
K23 Disorders of oesophagus in diseases classified elsewhere
0.632 0.368 0.000
M24 Other specific joint derangements
0.632 0.368 0.000
M14 Arthropathies in other diseases classified elsewhere
0.631 0.369 0.000
M12 Other specific arthropathies
0.631 0.369 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.631 0.369 0.000
M08 Juvenile arthritis
0.631 0.369 0.000
Q50-Q56 Congenital malformations of genital organs
0.631 0.369 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.630 0.369 0.000
I72 Other aneurysm
0.630 0.370 0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants
0.629 0.371 0.000
D35.1 Parathyroid gland
0.629 0.371 0.000
H44.9 Disorder of globe, unspecified
0.627 0.373 0.000
H44.8 Other disorders of globe
0.627 0.373 0.000
H44.7 Retained (old) intraocular foreign body, nonmagnetic
0.627 0.373 0.000
H44.6 Retained (old) intraocular foreign body, magnetic
0.627 0.373 0.000
H44.5 Degenerated conditions of globe
0.627 0.373 0.000
H44.4 Hypotony of eye
0.627 0.373 0.000
H44.3 Other degenerative disorders of globe
0.627 0.373 0.000
H44.1 Other endophthalmitis
0.627 0.373 0.000
N00-N08 Glomerular diseases
0.627 0.373 0.000
M05 Seropositive rheumatoid arthritis
0.626 0.374 0.000
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness
0.626 0.374 0.000
E65-E68 Obesity and other hyperalimentation
0.625 0.375 0.000
H02.7 Other degenerative disorders of eyelid and periocular area
0.625 0.375 0.000
H02.2 Lagophthalmos
0.625 0.375 0.000
Q80-Q89 Other congenital malformations
0.623 0.377 0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.623 0.377 0.000
I22.1 Subsequent myocardial infarction of inferior wall
0.623 0.377 0.000
M47.86 Other spondylosis (Lumbar region)
0.623 0.377 0.000
D68.2 Hereditary deficiency of other clotting factors
0.622 0.377 0.000
M11 Other crystal arthropathies
0.622 0.378 0.000
M07 Psoriatic and enteropathic arthropathies
0.622 0.378 0.000
K14.0 Glossitis
0.621 0.379 0.000
D36 Benign neoplasm of other and unspecified sites
0.619 0.381 0.000
D63.0 Anaemia in neoplastic disease
0.619 0.381 0.000
M79.7 Fibromyalgia
0.619 0.381 0.000
R47-R49 Symptoms and signs involving speech and voice
0.619 0.381 0.000
R61 Hyperhidrosis
0.618 0.382 0.000
H02.5 Other disorders affecting eyelid function
0.618 0.382 0.000
R45 Symptoms and signs involving emotional state
0.617 0.383 0.000
G25.8 Other specified extrapyramidal and movement disorders
0.617 0.383 0.000
K55 Vascular disorders of intestine
0.617 0.383 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.617 0.383 0.000
I80.9 Phlebitis and thrombophlebitis of unspecified site
0.616 0.383 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.616 0.384 0.000
G45.8 Other transient cerebral ischaemic attacks and related syndromes
0.616 0.384 0.000
G45.4 Transient global amnesia
0.616 0.384 0.000
G45.3 Amaurosis fugax
0.616 0.384 0.000
G45.2 Multiple and bilateral precerebral artery syndromes
0.616 0.384 0.000
G45.1 Carotid artery syndrome (hemispheric)
0.616 0.384 0.000
G45.0 Vertebro-basilar artery syndrome
0.616 0.384 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.615 0.384 0.000
R62 Lack of expected normal physiological development
0.615 0.384 0.000
R57 Shock, not elsewhere classified
0.615 0.384 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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