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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs114835835
log Bayes Factor = 12.4739
Chromosome 2   position 207,809,544  (GRCh37) Explore rs114835835 on Ensembl!
Variant rs114835835 is part of Cluster X0126

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M70-M79 Other soft tissue disorders
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
M75 Shoulder lesions
0.999 0.001 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.999 0.001 0.000
M75.4 Impingement syndrome of shoulder
0.999 0.001 0.000
M15-M19 Arthrosis
0.994 0.006 0.000
M05-M14 Inflammatory polyarthropathies
0.993 0.007 0.000
M79.6 Pain in limb
0.990 0.010 0.000
Chapter IX Diseases of the circulatory system
0.989 0.011 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.988 0.012 0.000
M20-M25 Other joint disorders
0.987 0.013 0.000
S00-S09 Injuries to the head
0.986 0.014 0.000
M17 Gonarthrosis [arthrosis of knee]
0.985 0.015 0.000
Chapter XX External causes of morbidity and mortality
0.984 0.016 0.000
I30-I52 Other forms of heart disease
0.981 0.019 0.000
M17.1 Other primary gonarthrosis
0.977 0.023 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.974 0.026 0.000
M13 Other arthritis
0.974 0.026 0.000
M23 Internal derangement of knee
0.972 0.028 0.000
M79.66 Pain in limb (Lower leg)
0.970 0.030 0.000
M50-M54 Other dorsopathies
0.967 0.033 0.000
M13.9 Arthritis, unspecified
0.957 0.043 0.000
Chapter VI Diseases of the nervous system
0.948 0.052 0.000
W00-W19 Falls
0.948 0.052 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.947 0.053 0.000
S60-S69 Injuries to the wrist and hand
0.938 0.062 0.000
I60-I69 Cerebrovascular diseases
0.934 0.066 0.000
M06 Other rheumatoid arthritis
0.931 0.069 0.000
M23.8 Other internal derangements of knee
0.930 0.070 0.000
M13.99 Arthritis, unspecified (Site unspecified)
0.928 0.072 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.924 0.076 0.000
W19 Unspecified fall
0.924 0.076 0.000
I51 Complications and ill-defined descriptions of heart disease
0.923 0.077 0.000
S01 Open wound of head
0.922 0.078 0.000
S20-S29 Injuries to the thorax
0.921 0.079 0.000
M54 Dorsalgia
0.917 0.083 0.000
M35 Other systemic involvement of connective tissue
0.916 0.084 0.000
M19 Other arthrosis
0.914 0.086 0.000
S01.8 Open wound of other parts of head
0.912 0.088 0.000
M13.91 Arthritis, unspecified (Shoulder region)
0.911 0.089 0.000
M50 Cervical disk disorders
0.898 0.101 0.000
I51.7 Cardiomegaly
0.882 0.118 0.000
M79.69 Pain in limb (Site unspecified)
0.881 0.119 0.000
M79.8 Other specified soft tissue disorders
0.878 0.122 0.000
M75.1 Rotator cuff syndrome
0.875 0.125 0.000
I45 Other conduction disorders
0.874 0.126 0.000
I20-I25 Ischaemic heart diseases
0.874 0.126 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.873 0.127 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.870 0.130 0.000
I69 Sequelae of cerebrovascular disease
0.870 0.130 0.000
M06.9 Rheumatoid arthritis, unspecified
0.866 0.134 0.000
M79.7 Fibromyalgia
0.862 0.137 0.000
I63 Cerebral infarction
0.861 0.139 0.000
G90-G99 Other disorders of the nervous system
0.858 0.142 0.000
M19.9 Arthrosis, unspecified
0.854 0.146 0.000
M35.3 Polymyalgia rheumatica
0.853 0.147 0.000
S06 Intracranial injury
0.852 0.148 0.000
M13.97 Arthritis, unspecified (Ankle and foot)
0.851 0.149 0.000
W19.9 Unspecified place
0.850 0.150 0.000
I20 Angina pectoris
0.847 0.153 0.000
M18 Arthrosis of first carpometacarpal joint
0.846 0.154 0.000
M24 Other specific joint derangements
0.846 0.154 0.000
M50.3 Other cervical disk degeneration
0.845 0.155 0.000
M79.63 Pain in limb (Forearm)
0.843 0.157 0.000
T84.1 Mechanical complication of internal fixation device of bones of limb
0.843 0.157 0.000
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.841 0.159 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.841 0.159 0.000
M19.91 Arthrosis, unspecified (Shoulder region)
0.840 0.160 0.000
M23.89 Other internal derangements of knee (Unspecified ligament or Unspecified meniscus)
0.839 0.160 0.000
T66-T78 Other and unspecified effects of external causes
0.838 0.162 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.835 0.165 0.000
S02 Fracture of skull and facial bones
0.832 0.168 0.000
I20.0 Unstable angina
0.826 0.174 0.000
I33 Acute and subacute endocarditis
0.822 0.178 0.000
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.820 0.180 0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]
0.820 0.180 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.819 0.181 0.000
Y86 Sequelae of other accidents
0.817 0.183 0.000
M86-M90 Other osteopathies
0.817 0.183 0.000
S00 Superficial injury of head
0.815 0.185 0.000
M79.65 Pain in limb (Pelvic region and thigh)
0.815 0.185 0.000
I47 Paroxysmal tachycardia
0.814 0.186 0.000
S05 Injury of eye and orbit
0.813 0.187 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.812 0.188 0.000
M60-M63 Disorders of muscles
0.811 0.188 0.000
S40-S49 Injuries to the shoulder and upper arm
0.810 0.190 0.000
W19.2 School, other institution and public administrative area
0.808 0.192 0.000
S60 Superficial injury of wrist and hand
0.807 0.193 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.805 0.195 0.000
S61 Open wound of wrist and hand
0.803 0.197 0.000
M54.3 Sciatica
0.803 0.197 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.801 0.198 0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis
0.801 0.199 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.801 0.199 0.000
T93 Sequelae of injuries of lower limb
0.799 0.201 0.000
M13.94 Arthritis, unspecified (Hand)
0.797 0.203 0.000
M79.0 Rheumatism, unspecified
0.796 0.204 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.796 0.204 0.000
I45.1 Other and unspecified right bundle-branch block
0.795 0.205 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.794 0.206 0.000
Q60-Q64 Congenital malformations of the urinary system
0.793 0.207 0.000
M79.2 Neuralgia and neuritis, unspecified
0.790 0.210 0.000
W20-W49 Exposure to inanimate mechanical forces
0.789 0.211 0.000
I60 Subarachnoid haemorrhage
0.786 0.214 0.000
Chapter VIII Diseases of the ear and mastoid process
0.786 0.214 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.785 0.215 0.000
W19.4 Street and highway
0.784 0.216 0.000
I42 Cardiomyopathy
0.782 0.218 0.000
Chapter I Certain infectious and parasitic diseases
0.782 0.218 0.000
M54.9 Dorsalgia, unspecified
0.781 0.219 0.000
M80-M85 Disorders of bone density and structure
0.780 0.220 0.000
G51 Facial nerve disorders
0.780 0.220 0.000
T84.2 Mechanical complication of internal fixation device of other bones
0.778 0.222 0.000
Q50-Q56 Congenital malformations of genital organs
0.777 0.223 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.776 0.224 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.776 0.224 0.000
M91-M94 Chondropathies
0.775 0.225 0.000
M17.0 Primary gonarthrosis, bilateral
0.774 0.226 0.000
M65-M68 Disorders of synovium and tendon
0.771 0.229 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.768 0.231 0.000
M17.3 Other posttraumatic gonarthrosis
0.767 0.233 0.000
T87 Complications peculiar to reattachment and amputation
0.766 0.234 0.000
M25 Other joint disorders, not elsewhere classified
0.765 0.235 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.764 0.235 0.000
I31 Other diseases of pericardium
0.764 0.236 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.763 0.237 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.763 0.237 0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.762 0.238 0.000
I38 Endocarditis, valve unspecified
0.762 0.238 0.000
T79-T79 Certain early complications of trauma
0.762 0.238 0.000
M13.0 Polyarthritis, unspecified
0.761 0.239 0.000
M50.1 Cervical disk disorder with radiculopathy
0.760 0.240 0.000
S90-S99 Injuries to the ankle and foot
0.759 0.240 0.000
M79.86 Other specified soft tissue disorders (Lower leg)
0.759 0.241 0.000
M54.5 Low back pain
0.758 0.242 0.000
I49 Other cardiac arrhythmias
0.758 0.242 0.000
I30 Acute pericarditis
0.757 0.243 0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts
0.757 0.243 0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts
0.757 0.243 0.000
M18.1 Other primary arthrosis of first carpometacarpal joint
0.754 0.246 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.753 0.247 0.000
S70-S79 Injuries to the hip and thigh
0.753 0.247 0.000
M11 Other crystal arthropathies
0.749 0.251 0.000
M75.9 Shoulder lesion, unspecified
0.748 0.252 0.000
M19.95 Arthrosis, unspecified (Pelvic region and thigh)
0.747 0.253 0.000
I69.3 Sequelae of cerebral infarction
0.745 0.255 0.000
M34 Systemic sclerosis
0.745 0.255 0.000
M75.3 Calcific tendinitis of shoulder
0.744 0.255 0.000
E10-E14 Diabetes mellitus
0.744 0.256 0.000
M79.70 Fibromyalgia (Multiple sites)
0.744 0.256 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.742 0.258 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.742 0.258 0.000
M06.4 Inflammatory polyarthropathy
0.742 0.258 0.000
I45.8 Other specified conduction disorders
0.741 0.259 0.000
G51.0 Bell's palsy
0.740 0.260 0.000
M79.64 Pain in limb (Hand)
0.738 0.262 0.000
M79.1 Myalgia
0.737 0.263 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.737 0.263 0.000
S67 Crushing injury of wrist and hand
0.735 0.265 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.733 0.266 0.000
M00-M03 Infectious arthropathies
0.733 0.267 0.000
S10-S19 Injuries to the neck
0.733 0.267 0.000
T92 Sequelae of injuries of upper limb
0.731 0.268 0.000
M23.4 Loose body in knee
0.731 0.269 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.731 0.269 0.000
S27 Injury of other and unspecified intrathoracic organs
0.730 0.270 0.000
V20-V29 Motorcycle rider injured in transport accident
0.730 0.270 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.730 0.270 0.000
M23.3 Other meniscus derangements
0.729 0.271 0.000
Chapter VII Diseases of the eye and adnexa
0.728 0.272 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.727 0.273 0.000
M54.39 Sciatica (Site unspecified)
0.727 0.273 0.000
S01.2 Open wound of nose
0.726 0.274 0.000
G95 Other diseases of spinal cord
0.726 0.274 0.000
B15-B19 Viral hepatitis
0.725 0.275 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.724 0.276 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.724 0.276 0.000
I35 Nonrheumatic aortic valve disorders
0.723 0.277 0.000
S29 Other and unspecified injuries of thorax
0.723 0.277 0.000
T78 Adverse effects, not elsewhere classified
0.722 0.278 0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.721 0.279 0.000
S60.8 Other superficial injuries of wrist and hand
0.720 0.280 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.719 0.281 0.000
V10-V19 Pedal cyclist injured in transport accident
0.719 0.281 0.000
I22 Subsequent myocardial infarction
0.719 0.281 0.000
M76 Enthesopathies of lower limb, excluding foot
0.717 0.283 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.717 0.283 0.000
M71 Other bursopathies
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
E10 Insulin-dependent diabetes mellitus
0.717 0.283 0.000
M75.8 Other shoulder lesions
0.716 0.283 0.000
M79.9 Soft tissue disorder, unspecified
0.716 0.284 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.716 0.284 0.000
M79.3 Panniculitis, unspecified
0.716 0.284 0.000
M21 Other acquired deformities of limbs
0.715 0.285 0.000
M45-M49 Spondylopathies
0.715 0.285 0.000
M79.5 Residual foreign body in soft tissue
0.714 0.286 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.714 0.286 0.000
G83 Other paralytic syndromes
0.714 0.286 0.000
I50 Heart failure
0.714 0.286 0.000
M15 Polyarthrosis
0.713 0.287 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.713 0.287 0.000
M14 Arthropathies in other diseases classified elsewhere
0.712 0.288 0.000
M12 Other specific arthropathies
0.712 0.288 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.712 0.288 0.000
M08 Juvenile arthritis
0.712 0.288 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.711 0.289 0.000
M23.29 Derangement of meniscus due to old tear or injury (Unspecified ligament or Unspecified meniscus)
0.711 0.289 0.000
S62 Fracture at wrist and hand level
0.710 0.289 0.000
M79.68 Pain in limb (Other)
0.710 0.290 0.000
M79.61 Pain in limb (Shoulder region)
0.710 0.290 0.000
I00-I02 Acute rheumatic fever
0.709 0.291 0.000
T86 Failure and rejection of transplanted organs and tissues
0.708 0.292 0.000
I33.0 Acute and subacute infective endocarditis
0.708 0.292 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.708 0.292 0.000
M33 Dermatopolymyositis
0.708 0.292 0.000
M32 Systemic lupus erythematosus
0.708 0.292 0.000
M30 Polyarteritis nodosa and related conditions
0.708 0.292 0.000
G70-G73 Diseases of myoneural junction and muscle
0.707 0.293 0.000
M35.0 Sicca syndrome [Sjogren]
0.707 0.293 0.000
S08 Traumatic amputation of part of head
0.707 0.293 0.000
S07 Crushing injury of head
0.707 0.293 0.000
S04 Injury of cranial nerves
0.707 0.293 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.707 0.293 0.000
M17.5 Other secondary gonarthrosis
0.706 0.294 0.000
M17.4 Other secondary gonarthrosis, bilateral
0.706 0.294 0.000
M17.2 Posttraumatic gonarthrosis, bilateral
0.706 0.294 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.706 0.294 0.000
Y35-Y36 Legal intervention and operations of war
0.706 0.294 0.000
Y10-Y34 Event of undetermined intent
0.706 0.294 0.000
Y00-Y09 Assault
0.706 0.294 0.000
X85-X99 Assault
0.706 0.294 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.706 0.294 0.000
X50-X57 Overexertion, travel and privation
0.706 0.294 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.706 0.294 0.000
X30-X39 Exposure to forces of nature
0.706 0.294 0.000
X20-X29 Contact with venomous animals and plants
0.706 0.294 0.000
X10-X19 Contact with heat and hot substances
0.706 0.294 0.000
X00-X09 Exposure to smoke, fire and flames
0.706 0.294 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.706 0.294 0.000
W75-W84 Other accidental threats to breathing
0.706 0.294 0.000
W65-W74 Accidental drowning and submersion
0.706 0.294 0.000
W50-W64 Exposure to animate mechanical forces
0.706 0.294 0.000
V98-V99 Other and unspecified transport accidents
0.706 0.294 0.000
V95-V97 Air and space transport accidents
0.706 0.294 0.000
V90-V94 Water transport accidents
0.706 0.294 0.000
V80-V89 Other land transport accidents
0.706 0.294 0.000
V70-V79 Bus occupant injured in transport accident
0.706 0.294 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.706 0.294 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.706 0.294 0.000
V40-V49 Car occupant injured in transport accident
0.706 0.294 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.706 0.294 0.000
V01-V09 Pedestrian injured in transport accident
0.706 0.294 0.000
I69.0 Sequelae of subarachnoid haemorrhage
0.706 0.294 0.000
X60-X84 Intentional self-harm
0.704 0.296 0.000
S22.2 Fracture of sternum
0.704 0.296 0.000
M77 Other enthesopathies
0.704 0.296 0.000
I52 Other heart disorders in diseases classified elsewhere
0.704 0.296 0.000
I48 Atrial fibrillation and flutter
0.704 0.296 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.704 0.296 0.000
I41 Myocarditis in diseases classified elsewhere
0.704 0.296 0.000
I40 Acute myocarditis
0.704 0.296 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.704 0.296 0.000
I37 Pulmonary valve disorders
0.704 0.296 0.000
I36 Nonrheumatic tricuspid valve disorders
0.704 0.296 0.000
I32 Pericarditis in diseases classified elsewhere
0.704 0.296 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.703 0.297 0.000
S69 Other and unspecified injuries of wrist and hand
0.702 0.298 0.000
T90 Sequelae of injuries of head
0.701 0.299 0.000
Q00-Q07 Congenital malformations of the nervous system
0.701 0.299 0.000
M79.82 Other specified soft tissue disorders (Upper arm)
0.700 0.300 0.000
S50-S59 Injuries to the elbow and forearm
0.699 0.301 0.000
M54.1 Radiculopathy
0.699 0.301 0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft
0.698 0.301 0.000
T84.3 Mechanical complication of other bone devices, implants and grafts
0.698 0.301 0.000
M13.8 Other specified arthritis
0.698 0.302 0.000
M13.1 Monoarthritis, not elsewhere classified
0.698 0.302 0.000
I62 Other nontraumatic intracranial haemorrhage
0.697 0.302 0.000
M23.9 Internal derangement of knee, unspecified
0.697 0.303 0.000
M23.5 Chronic instability of knee
0.697 0.303 0.000
M23.1 Discoid meniscus (congenital)
0.697 0.303 0.000
M23.0 Cystic meniscus
0.697 0.303 0.000
G93 Other disorders of brain
0.697 0.303 0.000
M19.90 Arthrosis, unspecified (Multiple sites)
0.694 0.306 0.000
S00.9 Superficial injury of head, part unspecified
0.694 0.306 0.000
M07 Psoriatic and enteropathic arthropathies
0.694 0.306 0.000
M54.57 Low back pain (Lumbosacral region)
0.693 0.307 0.000
M53 Other dorsopathies, not elsewhere classified
0.693 0.307 0.000
S20 Superficial injury of thorax
0.690 0.310 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.689 0.311 0.000
E10.9 Without complications
0.689 0.311 0.000
S05.8 Other injuries of eye and orbit
0.689 0.311 0.000
M75.2 Bicipital tendinitis
0.688 0.311 0.000
I20.9 Angina pectoris, unspecified
0.688 0.312 0.000
S02.6 Fracture of mandible
0.687 0.313 0.000
I61 Intracerebral haemorrhage
0.687 0.313 0.000
M13.93 Arthritis, unspecified (Forearm)
0.686 0.314 0.000
M13.92 Arthritis, unspecified (Upper arm)
0.686 0.314 0.000
M19.0 Primary arthrosis of other joints
0.685 0.315 0.000
M54.4 Lumbago with sciatica
0.682 0.318 0.000
M19.97 Arthrosis, unspecified (Ankle and foot)
0.682 0.318 0.000
S06.4 Epidural haemorrhage
0.682 0.318 0.000
S06.0 Concussion
0.681 0.319 0.000
M05 Seropositive rheumatoid arthritis
0.681 0.319 0.000
M24.1 Other articular cartilage disorders
0.680 0.320 0.000
W13 Fall from, out of or through building or structure
0.680 0.320 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.680 0.320 0.000
W18 Other fall on same level
0.680 0.320 0.000
W17 Other fall from one level to another
0.680 0.320 0.000
W16 Diving or jumping into water causing injury other than drowning or submersion
0.680 0.320 0.000
W15 Fall from cliff
0.680 0.320 0.000
W14 Fall from tree
0.680 0.320 0.000
W12 Fall on and from scaffolding
0.680 0.320 0.000
W11 Fall on and from ladder
0.680 0.320 0.000
W09 Fall involving playground equipment
0.680 0.320 0.000
W08 Fall involving other furniture
0.680 0.320 0.000
W07 Fall involving chair
0.680 0.320 0.000
W06 Fall involving bed
0.680 0.320 0.000
W05 Fall involving wheelchair
0.680 0.320 0.000
W04 Fall while being carried or supported by other persons
0.680 0.320 0.000
W03 Other fall on same level due to collision with, or pushing by, another person
0.680 0.320 0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards
0.680 0.320 0.000
W01 Fall on same level from slipping, tripping and stumbling
0.680 0.320 0.000
W00 Fall on same level involving ice and snow
0.680 0.320 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.679 0.321 0.000
Q80-Q89 Other congenital malformations
0.679 0.321 0.000
Q35-Q37 Cleft lip and cleft palate
0.679 0.321 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.679 0.321 0.000
Chapter XXII Codes for special purposes
0.679 0.321 0.000
M06.0 Seronegative rheumatoid arthritis
0.679 0.321 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.677 0.323 0.000
M62 Other disorders of muscle
0.676 0.324 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.676 0.324 0.000
I51.9 Heart disease, unspecified
0.675 0.325 0.000
S00.3 Superficial injury of nose
0.673 0.327 0.000
S65 Injury of blood vessels at wrist and hand level
0.673 0.327 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.670 0.330 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.670 0.330 0.000
G81 Hemiplegia
0.669 0.331 0.000
M54.96 Dorsalgia, unspecified (Lumbar region)
0.669 0.331 0.000
G90 Disorders of autonomic nervous system
0.667 0.333 0.000
M23.83 Other internal derangements of knee (Medial collateral ligament or Other and unspecified medial meniscus)
0.667 0.333 0.000
M06.8 Other specified rheumatoid arthritis
0.667 0.333 0.000
M06.3 Rheumatoid nodule
0.667 0.333 0.000
M06.2 Rheumatoid bursitis
0.667 0.333 0.000
M06.1 Adult-onset Still's disease
0.667 0.333 0.000
M23.87 Other internal derangements of knee (Capsular ligament)
0.667 0.333 0.000
M23.86 Other internal derangements of knee (Other and unspecified lateral meniscus)
0.667 0.333 0.000
M23.85 Other internal derangements of knee (Posterior horn of lateral meniscus)
0.667 0.333 0.000
M23.84 Other internal derangements of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.667 0.333 0.000
M23.82 Other internal derangements of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.667 0.333 0.000
M23.80 Other internal derangements of knee (Multiple sites)
0.667 0.333 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.666 0.334 0.000
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)
0.665 0.335 0.000
M25.4 Effusion of joint
0.664 0.336 0.000
T93.2 Sequelae of other fractures of lower limb
0.664 0.336 0.000
I47.2 Ventricular tachycardia
0.664 0.336 0.000
T98 Sequelae of other and unspecified effects of external causes
0.662 0.337 0.000
T95 Sequelae of burns, corrosions and frostbite
0.662 0.337 0.000
T91 Sequelae of injuries of neck and trunk
0.662 0.337 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.662 0.337 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.662 0.337 0.000
W19.8 Other specified place
0.662 0.337 0.000
W19.5 Trade and service area
0.662 0.337 0.000
W19.0 Home
0.662 0.337 0.000
W19.7 Farm
0.662 0.337 0.000
W19.6 Industrial and construction area
0.662 0.337 0.000
W19.3 Sports and athletics area
0.662 0.337 0.000
W19.1 Residential institution
0.662 0.337 0.000
W10 Fall on and from stairs and steps
0.662 0.338 0.000
M79.79 Fibromyalgia (Site unspecified)
0.662 0.338 0.000
I51.6 Cardiovascular disease, unspecified
0.661 0.338 0.000
I51.5 Myocardial degeneration
0.661 0.338 0.000
I51.4 Myocarditis, unspecified
0.661 0.338 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.661 0.338 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.661 0.338 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.661 0.338 0.000
I51.0 Cardiac septal defect, acquired
0.661 0.338 0.000
S01.7 Multiple open wounds of head
0.661 0.339 0.000
S01.4 Open wound of cheek and temporomandibular area
0.661 0.339 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.660 0.340 0.000
S26 Injury of heart
0.660 0.340 0.000
S25 Injury of blood vessels of thorax
0.660 0.340 0.000
S24 Injury of nerves and spinal cord at thorax level
0.660 0.340 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.660 0.340 0.000
S21 Open wound of thorax
0.660 0.340 0.000
I47.9 Paroxysmal tachycardia, unspecified
0.660 0.340 0.000
E14 Unspecified diabetes mellitus
0.659 0.341 0.000
Q61 Cystic kidney disease
0.659 0.341 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.658 0.342 0.000
M54.8 Other dorsalgia
0.657 0.342 0.000
M54.0 Panniculitis affecting regions of neck and back
0.657 0.342 0.000
M86 Osteomyelitis
0.657 0.342 0.000
I63.8 Other cerebral infarction
0.657 0.343 0.000
M35.9 Systemic involvement of connective tissue, unspecified
0.657 0.343 0.000
M35.8 Other specified systemic involvement of connective tissue
0.657 0.343 0.000
M35.7 Hypermobility syndrome
0.657 0.343 0.000
M35.6 Relapsing panniculitis [Weber-Christian]
0.657 0.343 0.000
M35.5 Multifocal fibrosclerosis
0.657 0.343 0.000
M35.4 Diffuse (eosinophilic) fasciitis
0.657 0.343 0.000
M35.2 Behcet's disease
0.657 0.343 0.000
M35.1 Other overlap syndromes
0.657 0.343 0.000
M54.6 Pain in thoracic spine
0.656 0.344 0.000
M70.2 Olecranon bursitis
0.656 0.344 0.000
M19.8 Other specified arthrosis
0.655 0.345 0.000
M19.2 Other secondary arthrosis
0.655 0.345 0.000
I20.1 Angina pectoris with documented spasm
0.655 0.345 0.000
G58 Other mononeuropathies
0.653 0.346 0.000
M75.5 Bursitis of shoulder
0.653 0.347 0.000
M79.09 Rheumatism, unspecified (Site unspecified)
0.653 0.347 0.000
M24.0 Loose body in joint
0.652 0.348 0.000
I69.1 Sequelae of intracerebral haemorrhage
0.651 0.349 0.000
S42 Fracture of shoulder and upper arm
0.649 0.351 0.000
H43-H45 Disorders of vitreous body and globe
0.648 0.352 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.648 0.352 0.000
B18 Chronic viral hepatitis
0.647 0.353 0.000
I47.0 Reentry ventricular arrhythmia
0.645 0.355 0.000
M50.9 Cervical disk disorder, unspecified
0.644 0.356 0.000
M50.8 Other cervical disk disorders
0.644 0.356 0.000
M79.89 Other specified soft tissue disorders (Site unspecified)
0.644 0.356 0.000
T83.1 Mechanical complication of other urinary devices and implants
0.643 0.357 0.000
Y83.3 Surgical operation with formation of external stoma
0.642 0.358 0.000
G80 Infantile cerebral palsy
0.642 0.358 0.000
S61.0 Open wound of finger(s) without damage to nail
0.641 0.359 0.000
M79.28 Neuralgia and neuritis, unspecified (Other)
0.640 0.359 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.640 0.360 0.000
W25 Contact with sharp glass
0.640 0.360 0.000
S06.5 Traumatic subdural haemorrhage
0.640 0.360 0.000
G91 Hydrocephalus
0.640 0.360 0.000
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level
0.639 0.361 0.000
G09 Sequelae of inflammatory diseases of central nervous system
0.639 0.361 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.638 0.361 0.000
I51.8 Other ill-defined heart diseases
0.638 0.362 0.000
T88.6 Anaphylactic shock due to adverse effect of correct drug or medicament properly administered
0.638 0.362 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.637 0.363 0.000
G30-G32 Other degenerative diseases of the nervous system
0.636 0.363 0.000
M19.1 Posttraumatic arthrosis of other joints
0.635 0.364 0.000
S06.3 Focal brain injury
0.635 0.365 0.000
T78.4 Allergy, unspecified
0.635 0.365 0.000
I63.9 Cerebral infarction, unspecified
0.635 0.365 0.000
M84 Disorders of continuity of bone
0.634 0.366 0.000
I44 Atrioventricular and left bundle-branch block
0.634 0.366 0.000
M10 Gout
0.634 0.366 0.000
S61.7 Multiple open wounds of wrist and hand
0.634 0.366 0.000
Q66 Congenital deformities of feet
0.634 0.366 0.000
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.633 0.367 0.000
S22.20 Fracture of sternum (closed)
0.631 0.369 0.000
S00.2 Other superficial injuries of eyelid and periocular area
0.631 0.369 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.630 0.369 0.000
S02.4 Fracture of malar and maxillary bones
0.630 0.370 0.000
M79.88 Other specified soft tissue disorders (Other)
0.629 0.371 0.000
M79.87 Other specified soft tissue disorders (Ankle and foot)
0.629 0.371 0.000
M79.85 Other specified soft tissue disorders (Pelvic region and thigh)
0.629 0.371 0.000
M79.83 Other specified soft tissue disorders (Forearm)
0.629 0.371 0.000
M79.81 Other specified soft tissue disorders (Shoulder region)
0.629 0.371 0.000
M79.80 Other specified soft tissue disorders (Multiple sites)
0.629 0.371 0.000
S64 Injury of nerves at wrist and hand level
0.629 0.371 0.000
S02.0 Fracture of vault of skull
0.628 0.372 0.000
H90-H95 Other disorders of ear
0.628 0.372 0.000
M40-M43 Deforming dorsopathies
0.627 0.372 0.000
I45.4 Nonspecific intraventricular block
0.626 0.373 0.000
I45.3 Trifascicular block
0.626 0.373 0.000
I45.2 Bifascicular block
0.626 0.373 0.000
I45.0 Right fascicular block
0.626 0.373 0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments
0.626 0.373 0.000
I23 Certain current complications following acute myocardial infarction
0.626 0.374 0.000
M23.27 Derangement of meniscus due to old tear or injury-Capsular
0.626 0.374 0.000
I35.8 Other aortic valve disorders
0.626 0.374 0.000
I46 Cardiac arrest
0.625 0.375 0.000
W29 Contact with other powered hand tools and household machinery
0.624 0.375 0.000
S02.1 Fracture of base of skull
0.624 0.376 0.000
T93.9 Sequelae of unspecified injury of lower limb
0.624 0.376 0.000
Y89 Sequelae of other external causes
0.623 0.376 0.000
Y87 Sequelae of intentional self-harm, assault and events of undetermined intent
0.623 0.376 0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.623 0.376 0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.623 0.376 0.000
S61.9 Open wound of wrist and hand, part unspecified
0.623 0.377 0.000
M88 Paget's disease of bone [osteitis deformans]
0.622 0.378 0.000
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)
0.621 0.379 0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified
0.621 0.379 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.621 0.379 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.621 0.379 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.621 0.379 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.621 0.379 0.000
S01.3 Open wound of ear
0.619 0.380 0.000
Y83.8 Other surgical procedures
0.619 0.381 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.619 0.381 0.000
I45.5 Other specified heart block
0.619 0.381 0.000
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)
0.619 0.381 0.000
M79.78 Fibromyalgia (Other)
0.618 0.382 0.000
M79.77 Fibromyalgia (Ankle and foot)
0.618 0.382 0.000
M79.76 Fibromyalgia (Lower leg)
0.618 0.382 0.000
M79.75 Fibromyalgia (Pelvic region and thigh)
0.618 0.382 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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