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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs115011873
log Bayes Factor = 13.7122
Chromosome 2   position 131,517,553  (GRCh37) Explore rs115011873 on Ensembl!
Variant rs115011873 is part of Cluster X0201

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
I30-I52 Other forms of heart disease
0.999 0.001 0.000
E10-E14 Diabetes mellitus
0.999 0.001 0.000
Chapter V Mental and behavioural disorders
0.997 0.003 0.000
S80-S89 Injuries to the knee and lower leg
0.992 0.008 0.000
I50 Heart failure
0.992 0.008 0.000
Chapter XX External causes of morbidity and mortality
0.991 0.009 0.000
E10 Insulin-dependent diabetes mellitus
0.991 0.009 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.991 0.009 0.000
F30-F39 Mood [affective] disorders
0.990 0.010 0.000
Chapter XXI Factors influencing health status and contact with health services
0.985 0.015 0.000
Chapter VI Diseases of the nervous system
0.982 0.018 0.000
S82 Fracture of lower leg, including ankle
0.979 0.021 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.976 0.024 0.000
I50.1 Left ventricular failure
0.975 0.025 0.000
E11 Non-insulin-dependent diabetes mellitus
0.973 0.027 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.972 0.028 0.000
F32 Depressive episode
0.971 0.029 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.966 0.034 0.000
D50-D53 Nutritional anaemias
0.964 0.036 0.000
I45 Other conduction disorders
0.964 0.036 0.000
Z60 Problems related to social environment
0.961 0.039 0.000
S82.8 Fractures of other parts of lower leg
0.961 0.039 0.000
E10.9 Without complications
0.961 0.039 0.000
I51 Complications and ill-defined descriptions of heart disease
0.959 0.041 0.000
Z60.2 Living alone
0.954 0.046 0.000
S60-S69 Injuries to the wrist and hand
0.952 0.048 0.000
S82.80 Fractures of other parts of lower leg (closed)
0.948 0.052 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.947 0.053 0.000
F41 Other anxiety disorders
0.946 0.054 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.945 0.055 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.944 0.056 0.000
F32.9 Depressive episode, unspecified
0.943 0.057 0.000
G90-G99 Other disorders of the nervous system
0.942 0.058 0.000
D50 Iron deficiency anaemia
0.940 0.060 0.000
Z53 Persons encountering health services for specifie procedures, not carried out
0.937 0.063 0.000
I50.0 Congestive heart failure
0.935 0.065 0.000
E65-E68 Obesity and other hyperalimentation
0.930 0.070 0.000
F41.9 Anxiety disorder, unspecified
0.926 0.074 0.000
F31 Bipolar affective disorder
0.920 0.080 0.000
D50.9 Iron deficiency anaemia, unspecified
0.914 0.086 0.000
Chapter VII Diseases of the eye and adnexa
0.913 0.087 0.000
Z53.0 Procedure not carried out because of contraindication
0.912 0.088 0.000
I45.1 Other and unspecified right bundle-branch block
0.895 0.105 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.891 0.109 0.000
E11.4 With neurological complications
0.887 0.113 0.000
M05-M14 Inflammatory polyarthropathies
0.886 0.114 0.000
D60-D64 Aplastic and other anaemias
0.885 0.115 0.000
Chapter XI Diseases of the digestive system
0.885 0.115 0.000
G40-G47 Episodic and paroxysmal disorders
0.883 0.117 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.882 0.118 0.000
E66 Obesity
0.881 0.119 0.000
I31 Other diseases of pericardium
0.879 0.121 0.000
I51.9 Heart disease, unspecified
0.876 0.124 0.000
E20-E35 Disorders of other endocrine glands
0.876 0.124 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.875 0.125 0.000
I05-I09 Chronic rheumatic heart diseases
0.874 0.126 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.871 0.129 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.868 0.132 0.000
Chapter I Certain infectious and parasitic diseases
0.860 0.140 0.000
S61 Open wound of wrist and hand
0.859 0.141 0.000
F31.9 Bipolar affective disorder, unspecified
0.857 0.143 0.000
I10-I15 Hypertensive diseases
0.854 0.146 0.000
H53-H54 Visual disturbances and blindness
0.852 0.148 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.851 0.149 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.849 0.151 0.000
I51.7 Cardiomegaly
0.848 0.152 0.000
G40 Epilepsy
0.848 0.152 0.000
Z53.9 Procedure not carried out, unspecified reason
0.842 0.158 0.000
D80-D89 Certain disorders involving the immune mechanism
0.840 0.160 0.000
Y57 Other and unspecified drugs and medicaments
0.840 0.160 0.000
E66.9 Obesity, unspecified
0.836 0.164 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.835 0.165 0.000
M45-M49 Spondylopathies
0.833 0.167 0.000
W20-W49 Exposure to inanimate mechanical forces
0.833 0.167 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.833 0.167 0.000
M06 Other rheumatoid arthritis
0.831 0.169 0.000
Z49 Care involving dialysis
0.828 0.172 0.000
E11.9 Without complications
0.828 0.172 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.826 0.174 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.824 0.176 0.000
K65-K67 Diseases of peritoneum
0.824 0.176 0.000
E10.0 With coma
0.823 0.177 0.000
F32.3 Severe depressive episode with psychotic symptoms
0.822 0.178 0.000
E10.8 With unspecified complications
0.821 0.179 0.000
G99.2 Myelopathy in diseases classified elsewhere
0.820 0.180 0.000
Y44 Agents primarily affecting blood constituents
0.819 0.181 0.000
E10.4 With neurological complications
0.817 0.183 0.000
S90-S99 Injuries to the ankle and foot
0.816 0.184 0.000
S82.2 Fracture of shaft of tibia
0.812 0.188 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.812 0.188 0.000
Z45 Adjustment and management of implanted device
0.810 0.190 0.000
A30-A49 Other bacterial diseases
0.809 0.191 0.000
Q00-Q07 Congenital malformations of the nervous system
0.807 0.193 0.000
E11.2 With renal complications
0.807 0.193 0.000
I45.2 Bifascicular block
0.805 0.195 0.000
I08 Multiple valve diseases
0.803 0.197 0.000
S62 Fracture at wrist and hand level
0.798 0.202 0.000
I12 Hypertensive renal disease
0.795 0.205 0.000
I31.3 Pericardial effusion (noninflammatory)
0.793 0.206 0.000
D52 Folate deficiency anaemia
0.792 0.208 0.000
H54 Blindness and low vision
0.792 0.208 0.000
E13 Other specified diabetes mellitus
0.791 0.208 0.000
K70-K77 Diseases of liver
0.791 0.209 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.790 0.210 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.790 0.210 0.000
E10.2 With renal complications
0.784 0.216 0.000
S81 Open wound of lower leg
0.781 0.219 0.000
H43-H45 Disorders of vitreous body and globe
0.781 0.219 0.000
M60-M63 Disorders of muscles
0.780 0.220 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.779 0.221 0.000
F41.2 Mixed anxiety and depressive disorder
0.778 0.222 0.000
A41 Other septicaemia
0.778 0.222 0.000
K35-K38 Diseases of appendix
0.778 0.222 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.777 0.223 0.000
E14 Unspecified diabetes mellitus
0.777 0.223 0.000
Z53.2 Procedure not carried out because of patient's decision for other and unspecified reasons
0.777 0.223 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.775 0.225 0.000
M70-M79 Other soft tissue disorders
0.773 0.227 0.000
S82.6 Fracture of lateral malleolus
0.772 0.228 0.000
Z22 Carrier of infectious disease
0.771 0.229 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.771 0.229 0.000
M06.9 Rheumatoid arthritis, unspecified
0.771 0.229 0.000
S86 Injury of muscle and tendon at lower leg level
0.770 0.230 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.770 0.230 0.000
S70-S79 Injuries to the hip and thigh
0.768 0.232 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.766 0.234 0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes
0.766 0.234 0.000
I12.0 Hypertensive renal disease with renal failure
0.764 0.236 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.763 0.237 0.000
I45.9 Conduction disorder, unspecified
0.763 0.237 0.000
I60-I69 Cerebrovascular diseases
0.762 0.238 0.000
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)
0.761 0.239 0.000
D61 Other aplastic anaemias
0.760 0.240 0.000
E11.3 With ophthalmic complications
0.759 0.241 0.000
Z63 Other problems related to primary support group, including family circumstances
0.757 0.243 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.756 0.244 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.755 0.245 0.000
D62 Acute posthaemorrhagic anaemia
0.754 0.246 0.000
S20-S29 Injuries to the thorax
0.753 0.247 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.753 0.247 0.000
M47 Spondylosis
0.752 0.248 0.000
G40.9 Epilepsy, unspecified
0.751 0.249 0.000
Y52 Agents primarily affecting the cardiovascular system
0.750 0.250 0.000
S61.8 Open wound of other parts of wrist and hand
0.749 0.251 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.748 0.252 0.000
Chapter VIII Diseases of the ear and mastoid process
0.747 0.253 0.000
M86-M90 Other osteopathies
0.747 0.253 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.746 0.254 0.000
G96 Other disorders of central nervous system
0.746 0.254 0.000
S82.1 Fracture of upper end of tibia
0.746 0.254 0.000
Y43 Primarily systemic agents
0.745 0.255 0.000
T79-T79 Certain early complications of trauma
0.744 0.255 0.000
Chapter XXII Codes for special purposes
0.743 0.256 0.000
I47 Paroxysmal tachycardia
0.743 0.257 0.000
Y57.9 Drug or medicament, unspecified
0.742 0.258 0.000
Q60-Q64 Congenital malformations of the urinary system
0.742 0.258 0.000
T90 Sequelae of injuries of head
0.742 0.258 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.742 0.258 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.741 0.259 0.000
S68 Traumatic amputation of wrist and hand
0.740 0.260 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.738 0.262 0.000
I34 Nonrheumatic mitral valve disorders
0.738 0.262 0.000
E70-E90 Metabolic disorders
0.737 0.263 0.000
K66 Other disorders of peritoneum
0.736 0.264 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.734 0.266 0.000
Z43 Attention to artificial openings
0.734 0.266 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.734 0.266 0.000
E11.5 With peripheral circulatory complications
0.734 0.266 0.000
F45 Somatoform disorders
0.734 0.266 0.000
S61.1 Open wound of finger(s) with damage to nail
0.734 0.266 0.000
G95 Other diseases of spinal cord
0.734 0.266 0.000
G62 Other polyneuropathies
0.733 0.267 0.000
K01 Embedded and impacted teeth
0.733 0.267 0.000
K11 Diseases of salivary glands
0.732 0.268 0.000
G20-G26 Extrapyramidal and movement disorders
0.730 0.270 0.000
F33 Recurrent depressive disorder
0.727 0.272 0.000
G70-G73 Diseases of myoneural junction and muscle
0.727 0.273 0.000
Z45.2 Adjustment and management of vascular access device
0.727 0.273 0.000
W00-W19 Falls
0.726 0.274 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.726 0.274 0.000
Q21 Congenital malformations of cardiac septa
0.724 0.276 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.723 0.277 0.000
I51.8 Other ill-defined heart diseases
0.722 0.278 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.721 0.279 0.000
I45.6 Preexcitation syndrome
0.721 0.279 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.720 0.280 0.000
F32.2 Severe depressive episode without psychotic symptoms
0.718 0.282 0.000
I46 Cardiac arrest
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S10-S19 Injuries to the neck
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
I52 Other heart disorders in diseases classified elsewhere
0.716 0.283 0.000
I48 Atrial fibrillation and flutter
0.716 0.283 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.716 0.283 0.000
I41 Myocarditis in diseases classified elsewhere
0.716 0.283 0.000
I40 Acute myocarditis
0.716 0.283 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.716 0.283 0.000
I37 Pulmonary valve disorders
0.716 0.283 0.000
I36 Nonrheumatic tricuspid valve disorders
0.716 0.283 0.000
I32 Pericarditis in diseases classified elsewhere
0.716 0.283 0.000
I30 Acute pericarditis
0.716 0.283 0.000
Y45.0 Opioids and related analgesics
0.716 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.716 0.283 0.000
F99-F99 Unspecified mental disorder
0.715 0.285 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.715 0.285 0.000
F80-F89 Disorders of psychological development
0.715 0.285 0.000
F70-F79 Mental retardation
0.715 0.285 0.000
F60-F69 Disorders of adult personality and behaviour
0.715 0.285 0.000
Z54 Convalescence
0.714 0.286 0.000
A41.5 Septicaemia due to other Gram-negative organisms
0.713 0.287 0.000
M91-M94 Chondropathies
0.712 0.288 0.000
S82.0 Fracture of patella
0.712 0.288 0.000
W25 Contact with sharp glass
0.712 0.288 0.000
S89 Other and unspecified injuries of lower leg
0.711 0.288 0.000
S88 Traumatic amputation of lower leg
0.711 0.288 0.000
S87 Crushing injury of lower leg
0.711 0.288 0.000
S85 Injury of blood vessels at lower leg level
0.711 0.288 0.000
S84 Injury of nerves at lower leg level
0.711 0.288 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.711 0.289 0.000
Y35-Y36 Legal intervention and operations of war
0.711 0.289 0.000
Y10-Y34 Event of undetermined intent
0.711 0.289 0.000
Y00-Y09 Assault
0.711 0.289 0.000
X85-X99 Assault
0.711 0.289 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.711 0.289 0.000
X50-X57 Overexertion, travel and privation
0.711 0.289 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.711 0.289 0.000
X30-X39 Exposure to forces of nature
0.711 0.289 0.000
X20-X29 Contact with venomous animals and plants
0.711 0.289 0.000
X10-X19 Contact with heat and hot substances
0.711 0.289 0.000
X00-X09 Exposure to smoke, fire and flames
0.711 0.289 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.711 0.289 0.000
W75-W84 Other accidental threats to breathing
0.711 0.289 0.000
W65-W74 Accidental drowning and submersion
0.711 0.289 0.000
W50-W64 Exposure to animate mechanical forces
0.711 0.289 0.000
V98-V99 Other and unspecified transport accidents
0.711 0.289 0.000
V95-V97 Air and space transport accidents
0.711 0.289 0.000
V90-V94 Water transport accidents
0.711 0.289 0.000
V80-V89 Other land transport accidents
0.711 0.289 0.000
V70-V79 Bus occupant injured in transport accident
0.711 0.289 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.711 0.289 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.711 0.289 0.000
V40-V49 Car occupant injured in transport accident
0.711 0.289 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.711 0.289 0.000
V01-V09 Pedestrian injured in transport accident
0.711 0.289 0.000
E10.7 With multiple complications
0.711 0.289 0.000
E10.6 With other specified complications
0.711 0.289 0.000
E10.5 With peripheral circulatory complications
0.711 0.289 0.000
D55-D59 Haemolytic anaemias
0.710 0.290 0.000
F38 Other mood [affective] disorders
0.710 0.290 0.000
F34 Persistent mood [affective] disorders
0.710 0.290 0.000
F30 Manic episode
0.710 0.290 0.000
F39 Unspecified mood [affective] disorder
0.710 0.290 0.000
T86 Failure and rejection of transplanted organs and tissues
0.710 0.290 0.000
G60 Hereditary and idiopathic neuropathy
0.709 0.291 0.000
Q05 Spina bifida
0.709 0.291 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.708 0.292 0.000
K65 Peritonitis
0.708 0.292 0.000
E40-E46 Malnutrition
0.706 0.294 0.000
E10.3 With ophthalmic complications
0.706 0.294 0.000
Y44.2 Anticoagulants
0.706 0.294 0.000
Q80-Q89 Other congenital malformations
0.705 0.295 0.000
S67 Crushing injury of wrist and hand
0.704 0.296 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.704 0.296 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.704 0.296 0.000
X60-X84 Intentional self-harm
0.702 0.297 0.000
S82.9 Fracture of lower leg, part unspecified
0.702 0.298 0.000
S82.7 Multiple fractures of lower leg
0.702 0.298 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.702 0.298 0.000
Z22.3 Carrier of other specified bacterial diseases
0.702 0.298 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.702 0.298 0.000
I45.5 Other specified heart block
0.702 0.298 0.000
E23 Hypofunction and other disorders of pituitary gland
0.701 0.298 0.000
M00-M03 Infectious arthropathies
0.701 0.299 0.000
H54.9 Unspecified visual impairment (binocular)
0.700 0.300 0.000
Y59 Other and unspecified vaccines and biological substances
0.700 0.300 0.000
Y58 Bacterial vaccines
0.700 0.300 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.700 0.300 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.700 0.300 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.700 0.300 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.700 0.300 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.700 0.300 0.000
Y48 Anaesthetics and therapeutic gases
0.700 0.300 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.700 0.300 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.700 0.300 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.700 0.300 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.698 0.302 0.000
E11.8 With unspecified complications
0.698 0.302 0.000
E11.7 With multiple complications
0.698 0.302 0.000
E11.6 With other specified complications
0.698 0.302 0.000
E11.1 With ketoacidosis
0.698 0.302 0.000
E11.0 With coma
0.698 0.302 0.000
Z49.0 Preparatory care for dialysis
0.698 0.302 0.000
Z65 Problems related to other psychosocial circumstances
0.697 0.303 0.000
Z64 Problems related to certain psychosocial circumstances
0.697 0.303 0.000
Z62 Other problems related to upbringing
0.697 0.303 0.000
Z61 Problems related to negative life events in childhood
0.697 0.303 0.000
Z59 Problems related to housing and economic circumstances
0.697 0.303 0.000
Z58 Problems related to physical environment
0.697 0.303 0.000
Z56 Problems related to employment and unemployment
0.697 0.303 0.000
Z55 Problems related to education and literacy
0.697 0.303 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.697 0.303 0.000
I33 Acute and subacute endocarditis
0.696 0.303 0.000
F32.8 Other depressive episodes
0.696 0.304 0.000
F32.1 Moderate depressive episode
0.696 0.304 0.000
F32.0 Mild depressive episode
0.696 0.304 0.000
T93 Sequelae of injuries of lower limb
0.696 0.304 0.000
V10-V19 Pedal cyclist injured in transport accident
0.696 0.304 0.000
S64 Injury of nerves at wrist and hand level
0.696 0.304 0.000
K50-K52 Noninfective enteritis and colitis
0.694 0.306 0.000
B25-B34 Other viral diseases
0.693 0.307 0.000
V20-V29 Motorcycle rider injured in transport accident
0.693 0.307 0.000
I08.1 Disorders of both mitral and tricuspid valves
0.693 0.307 0.000
S82.20 Fracture of shaft of tibia (closed)
0.693 0.307 0.000
M48 Other spondylopathies
0.693 0.307 0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.693 0.307 0.000
F48 Other neurotic disorders
0.692 0.307 0.000
F44 Dissociative [conversion] disorders
0.692 0.307 0.000
F42 Obsessive-compulsive disorder
0.692 0.307 0.000
K90-K93 Other diseases of the digestive system
0.691 0.309 0.000
D53 Other nutritional anaemias
0.691 0.309 0.000
S80 Superficial injury of lower leg
0.691 0.309 0.000
I45.8 Other specified conduction disorders
0.691 0.309 0.000
I45.4 Nonspecific intraventricular block
0.691 0.309 0.000
I45.3 Trifascicular block
0.691 0.309 0.000
I45.0 Right fascicular block
0.691 0.309 0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.691 0.309 0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms
0.691 0.309 0.000
Z60.9 Problem related to social environment, unspecified
0.689 0.311 0.000
Z60.8 Other problems related to social environment
0.689 0.311 0.000
Z60.5 Target of perceived adverse discrimination and persecution
0.689 0.311 0.000
Z60.4 Social exclusion and rejection
0.689 0.311 0.000
Z60.3 Acculturation difficulty
0.689 0.311 0.000
Z60.1 Atypical parenting situation
0.689 0.311 0.000
Z60.0 Problems of adjustment to life-cycle transitions
0.689 0.311 0.000
S82.86 Maisonneuve's fracture
0.689 0.311 0.000
S82.81 Fractures of other parts of lower leg (open)
0.689 0.311 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.689 0.311 0.000
M11 Other crystal arthropathies
0.688 0.312 0.000
M15-M19 Arthrosis
0.687 0.313 0.000
I51.6 Cardiovascular disease, unspecified
0.687 0.313 0.000
I51.5 Myocardial degeneration
0.687 0.313 0.000
I51.4 Myocarditis, unspecified
0.687 0.313 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.687 0.313 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.687 0.313 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.687 0.313 0.000
I51.0 Cardiac septal defect, acquired
0.687 0.313 0.000
Z57 Occupational exposure to risk-factors
0.687 0.313 0.000
G30-G32 Other degenerative diseases of the nervous system
0.687 0.313 0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)
0.686 0.314 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.685 0.315 0.000
K35 Acute appendicitis
0.685 0.315 0.000
K76 Other diseases of liver
0.685 0.315 0.000
K75 Other inflammatory liver diseases
0.685 0.315 0.000
D50.8 Other iron deficiency anaemias
0.685 0.315 0.000
E66.8 Other obesity
0.684 0.316 0.000
Z47 Other orthopaedic follow-up care
0.683 0.316 0.000
S69 Other and unspecified injuries of wrist and hand
0.683 0.317 0.000
S65 Injury of blood vessels at wrist and hand level
0.683 0.317 0.000
S60 Superficial injury of wrist and hand
0.683 0.317 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.683 0.317 0.000
Q50-Q56 Congenital malformations of genital organs
0.682 0.318 0.000
F31.0 Bipolar affective disorder, current episode hypomanic
0.682 0.318 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.682 0.318 0.000
M06.0 Seronegative rheumatoid arthritis
0.680 0.320 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.680 0.320 0.000
G93 Other disorders of brain
0.679 0.321 0.000
F41.8 Other specified anxiety disorders
0.678 0.322 0.000
F41.3 Other mixed anxiety disorders
0.678 0.322 0.000
F41.1 Generalised anxiety disorder
0.678 0.322 0.000
Z52 Donors of organs and tissues
0.678 0.322 0.000
Z44 Fitting and adjustment of external prosthetic device
0.678 0.322 0.000
E10.1 With ketoacidosis
0.677 0.323 0.000
S82.3 Fracture of lower end of tibia
0.677 0.323 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.677 0.323 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.677 0.323 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.677 0.323 0.000
Q35-Q37 Cleft lip and cleft palate
0.677 0.323 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.677 0.323 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.677 0.323 0.000
Z49.1 Extracorporeal dialysis
0.677 0.323 0.000
S82.5 Fracture of medial malleolus
0.676 0.323 0.000
S00-S09 Injuries to the head
0.676 0.324 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.676 0.324 0.000
G90 Disorders of autonomic nervous system
0.676 0.324 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.676 0.324 0.000
G92 Toxic encephalopathy
0.676 0.324 0.000
W21 Striking against or struck by sports equipment
0.675 0.325 0.000
H53 Visual disturbances
0.675 0.325 0.000
D50.1 Sideropenic dysphagia
0.674 0.326 0.000
H55-H59 Other disorders of eye and adnexa
0.673 0.327 0.000
Z53.1 Procedure not carried out because of patient's decision for reasons of belief or group pressure
0.672 0.328 0.000
D61.9 Aplastic anaemia, unspecified
0.670 0.329 0.000
D52.9 Folate deficiency anaemia, unspecified
0.669 0.331 0.000
E67 Other hyperalimentation
0.667 0.333 0.000
E68 Sequelae of hyperalimentation
0.667 0.333 0.000
E65 Localised adiposity
0.667 0.333 0.000
K01.1 Impacted teeth
0.667 0.333 0.000
S62.5 Fracture of thumb
0.667 0.333 0.000
E50-E64 Other nutritional deficiencies
0.665 0.335 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.665 0.335 0.000
Y42.7 Androgens and anabolic congeners
0.665 0.335 0.000
E22 Hyperfunction of pituitary gland
0.665 0.335 0.000
Y84.0 Cardiac catheterisation
0.665 0.335 0.000
I71 Aortic aneurysm and dissection
0.664 0.335 0.000
I65.2 Occlusion and stenosis of carotid artery
0.663 0.337 0.000
G99.0 Autonomic neuropathy in endocrine and metabolic diseases
0.661 0.339 0.000
M62 Other disorders of muscle
0.661 0.339 0.000
D86 Sarcoidosis
0.661 0.339 0.000
S82.4 Fracture of fibula alone
0.660 0.340 0.000
E14.9 Without complications
0.660 0.340 0.000
Y43.4 Immunosuppressive agents
0.660 0.340 0.000
F31.8 Other bipolar affective disorders
0.659 0.340 0.000
F31.7 Bipolar affective disorder, currently in remission
0.659 0.340 0.000
F31.6 Bipolar affective disorder, current episode mixed
0.659 0.340 0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms
0.659 0.340 0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms
0.659 0.340 0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression
0.659 0.340 0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms
0.659 0.340 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.659 0.340 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.658 0.341 0.000
M05 Seropositive rheumatoid arthritis
0.658 0.342 0.000
Z29 Need for other prophylactic measures
0.656 0.344 0.000
K04 Diseases of pulp and periapical tissues
0.655 0.345 0.000
H54.4 Blindness, one eye
0.654 0.346 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.653 0.347 0.000
F40 Phobic anxiety disorders
0.652 0.347 0.000
M80-M85 Disorders of bone density and structure
0.652 0.347 0.000
M07 Psoriatic and enteropathic arthropathies
0.652 0.348 0.000
S61.9 Open wound of wrist and hand, part unspecified
0.652 0.348 0.000
S91 Open wound of ankle and foot
0.652 0.348 0.000
S83.2 Tear of meniscus, current
0.651 0.349 0.000
M47.8 Other spondylosis
0.650 0.350 0.000
I08.0 Disorders of both mitral and aortic valves
0.649 0.351 0.000
F43 Reaction to severe stress, and adjustment disorders
0.649 0.351 0.000
M40-M43 Deforming dorsopathies
0.649 0.351 0.000
A41.0 Septicaemia due to Staphylococcus aureus
0.649 0.351 0.000
K09 Cysts of oral region, not elsewhere classified
0.649 0.351 0.000
I44 Atrioventricular and left bundle-branch block
0.649 0.351 0.000
I35 Nonrheumatic aortic valve disorders
0.649 0.351 0.000
S40-S49 Injuries to the shoulder and upper arm
0.648 0.351 0.000
Z13 Special screening examination for other diseases and disorders
0.648 0.352 0.000
H18 Other disorders of cornea
0.647 0.352 0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.647 0.353 0.000
H54.0 Blindness, both eyes
0.647 0.353 0.000
K10 Other diseases of jaws
0.646 0.354 0.000
Y84.2 Radiological procedure and radiotherapy
0.646 0.354 0.000
S50-S59 Injuries to the elbow and forearm
0.646 0.354 0.000
E86 Volume depletion
0.644 0.356 0.000
F41.0 Panic disorder [episodic paroxysmal anxiety]
0.643 0.357 0.000
E13.9 Without complications
0.643 0.357 0.000
A41.1 Septicaemia due to other specified staphylococcus
0.642 0.357 0.000
H43 Disorders of vitreous body
0.640 0.360 0.000
G94.1 Hydrocephalus in neoplastic disease
0.640 0.360 0.000
I60 Subarachnoid haemorrhage
0.639 0.361 0.000
G91 Hydrocephalus
0.639 0.361 0.000
T66-T78 Other and unspecified effects of external causes
0.639 0.361 0.000
K66.0 Peritoneal adhesions
0.639 0.361 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.639 0.361 0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
0.639 0.361 0.000
T87 Complications peculiar to reattachment and amputation
0.639 0.361 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.639 0.361 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.639 0.361 0.000
Z48 Other surgical follow-up care
0.638 0.361 0.000
Q05.9 Spina bifida, unspecified
0.638 0.361 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.638 0.362 0.000
T90.4 Sequelae of injury of eye and orbit
0.638 0.362 0.000
K11.2 Sialoadenitis
0.638 0.362 0.000
Y54.3 Benzothiadiazine derivatives
0.637 0.363 0.000
M10 Gout
0.636 0.364 0.000
S62.6 Fracture of other finger
0.636 0.364 0.000
E27 Other disorders of adrenal gland
0.635 0.365 0.000
M14 Arthropathies in other diseases classified elsewhere
0.635 0.365 0.000
M12 Other specific arthropathies
0.635 0.365 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.635 0.365 0.000
M08 Juvenile arthritis
0.635 0.365 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.635 0.365 0.000
I27 Other pulmonary heart diseases
0.634 0.366 0.000
K12 Stomatitis and related lesions
0.634 0.366 0.000
K76.0 Fatty (change of) liver, not elsewhere classified
0.634 0.366 0.000
Q23 Congenital malformations of aortic and mitral valves
0.633 0.367 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.633 0.367 0.000
G41 Status epilepticus
0.633 0.367 0.000
K13 Other diseases of lip and oral mucosa
0.633 0.367 0.000
E21.3 Hyperparathyroidism, unspecified
0.633 0.367 0.000
Z53.8 Procedure not carried out for other reasons
0.633 0.367 0.000
G64 Other disorders of peripheral nervous system
0.632 0.367 0.000
H44 Disorders of globe
0.632 0.368 0.000
I47.2 Ventricular tachycardia
0.632 0.368 0.000
I49 Other cardiac arrhythmias
0.632 0.368 0.000
M65-M68 Disorders of synovium and tendon
0.631 0.368 0.000
E66.2 Extreme obesity with alveolar hypoventilation
0.631 0.369 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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