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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs115043143
log Bayes Factor = 13.8566
Chromosome 4   position 29,985,599  (GRCh37) Explore rs115043143 on Ensembl!
Variant rs115043143 is part of Cluster X0059

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.999 0.001 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.997 0.003 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.996 0.004 0.000
S80-S89 Injuries to the knee and lower leg
0.990 0.010 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.990 0.010 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.990 0.010 0.000
M05-M14 Inflammatory polyarthropathies
0.989 0.011 0.000
I30-I52 Other forms of heart disease
0.988 0.012 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.986 0.014 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.985 0.015 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.984 0.016 0.000
I84 Haemorrhoids
0.983 0.017 0.000
I50 Heart failure
0.982 0.018 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.982 0.018 0.000
I60-I69 Cerebrovascular diseases
0.980 0.020 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.975 0.025 0.000
D70 Agranulocytosis
0.974 0.026 0.000
M13 Other arthritis
0.974 0.026 0.000
Chapter VII Diseases of the eye and adnexa
0.971 0.029 0.000
S50-S59 Injuries to the elbow and forearm
0.965 0.035 0.000
M50-M54 Other dorsopathies
0.963 0.037 0.000
M13.9 Arthritis, unspecified
0.963 0.037 0.000
E70-E90 Metabolic disorders
0.961 0.039 0.000
M13.99 Arthritis, unspecified (Site unspecified)
0.960 0.040 0.000
C78.7 Secondary malignant neoplasm of liver
0.959 0.041 0.000
L60-L75 Disorders of skin appendages
0.959 0.041 0.000
I84.6 Residual haemorrhoidal skin tags
0.957 0.043 0.000
I50.9 Heart failure, unspecified
0.956 0.044 0.000
S82 Fracture of lower leg, including ankle
0.954 0.046 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.950 0.050 0.000
I84.9 Unspecified haemorrhoids without complication
0.950 0.050 0.000
Chapter VI Diseases of the nervous system
0.944 0.056 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.942 0.058 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.941 0.059 0.000
L60 Nail disorders
0.939 0.061 0.000
L20-L30 Dermatitis and eczema
0.938 0.062 0.000
H25-H28 Disorders of lens
0.936 0.064 0.000
I50.0 Congestive heart failure
0.931 0.069 0.000
Chapter XX External causes of morbidity and mortality
0.928 0.072 0.000
M15-M19 Arthrosis
0.928 0.072 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.926 0.074 0.000
C78.0 Secondary malignant neoplasm of lung
0.923 0.077 0.000
L60.0 Ingrowing nail
0.915 0.085 0.000
H26 Other cataract
0.913 0.087 0.000
S82.8 Fractures of other parts of lower leg
0.913 0.087 0.000
Chapter XXI Factors influencing health status and contact with health services
0.905 0.095 0.000
C85.1 B-cell lymphoma, unspecified
0.902 0.098 0.000
C79 Secondary malignant neoplasm of other sites
0.899 0.101 0.000
M54 Dorsalgia
0.898 0.102 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.898 0.102 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.895 0.105 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.894 0.106 0.000
M19 Other arthrosis
0.891 0.109 0.000
S52 Fracture of forearm
0.890 0.110 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.889 0.111 0.000
S82.80 Fractures of other parts of lower leg (closed)
0.884 0.116 0.000
S81 Open wound of lower leg
0.882 0.118 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.873 0.127 0.000
M06 Other rheumatoid arthritis
0.873 0.127 0.000
I44 Atrioventricular and left bundle-branch block
0.873 0.127 0.000
H26.4 After-cataract
0.872 0.128 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.869 0.131 0.000
M19.9 Arthrosis, unspecified
0.867 0.133 0.000
I80 Phlebitis and thrombophlebitis
0.864 0.136 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.860 0.140 0.000
W00-W19 Falls
0.859 0.141 0.000
Z12 Special screening examination for neoplasms
0.859 0.141 0.000
E20-E35 Disorders of other endocrine glands
0.859 0.141 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.851 0.149 0.000
I63 Cerebral infarction
0.845 0.155 0.000
S52.5 Fracture of lower end of radius
0.844 0.156 0.000
D46 Myelodysplastic syndromes
0.836 0.164 0.000
I60 Subarachnoid haemorrhage
0.836 0.164 0.000
S80 Superficial injury of lower leg
0.836 0.164 0.000
M86-M90 Other osteopathies
0.836 0.164 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.834 0.166 0.000
S50 Superficial injury of forearm
0.834 0.166 0.000
L29 Pruritus
0.833 0.167 0.000
H55-H59 Other disorders of eye and adnexa
0.832 0.168 0.000
Z08.0 Follow-up examination after surgery for malignant neoplasm
0.832 0.168 0.000
S20-S29 Injuries to the thorax
0.829 0.171 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.828 0.172 0.000
S82.6 Fracture of lateral malleolus
0.828 0.172 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.828 0.172 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.824 0.176 0.000
E10-E14 Diabetes mellitus
0.822 0.178 0.000
Chapter I Certain infectious and parasitic diseases
0.822 0.178 0.000
D75 Other diseases of blood and blood-forming organs
0.821 0.179 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.821 0.179 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.819 0.181 0.000
I38 Endocarditis, valve unspecified
0.819 0.181 0.000
M50 Cervical disk disorders
0.818 0.182 0.000
M19.99 Arthrosis, unspecified (Site unspecified)
0.814 0.186 0.000
C60-C63 Malignant neoplasms of male genital organs
0.814 0.186 0.000
I49 Other cardiac arrhythmias
0.813 0.187 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.812 0.188 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.812 0.188 0.000
M18 Arthrosis of first carpometacarpal joint
0.811 0.189 0.000
S52.50 Fracture of lower end of radius (closed)
0.811 0.189 0.000
I84.7 Unspecified thrombosed haemorrhoids
0.810 0.190 0.000
C81 Hodgkin's disease
0.810 0.190 0.000
L30 Other dermatitis
0.810 0.190 0.000
E87.6 Hypokalaemia
0.807 0.193 0.000
M19.98 Arthrosis, unspecified (Other)
0.803 0.197 0.000
M45-M49 Spondylopathies
0.799 0.201 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.796 0.204 0.000
Z12.0 Special screening examination for neoplasm of stomach
0.795 0.205 0.000
I82 Other venous embolism and thrombosis
0.794 0.206 0.000
I69 Sequelae of cerebrovascular disease
0.792 0.208 0.000
M06.9 Rheumatoid arthritis, unspecified
0.791 0.209 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.791 0.209 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.791 0.209 0.000
M20-M25 Other joint disorders
0.790 0.210 0.000
S90-S99 Injuries to the ankle and foot
0.790 0.210 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.789 0.211 0.000
C85.7 Other specified types of non-Hodgkin's lymphoma
0.788 0.212 0.000
I46 Cardiac arrest
0.786 0.214 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.786 0.214 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.785 0.215 0.000
M13.96 Arthritis, unspecified (Lower leg)
0.785 0.215 0.000
L60.8 Other nail disorders
0.785 0.215 0.000
I84.8 Unspecified haemorrhoids with other complications
0.785 0.215 0.000
I44.7 Left bundle-branch block, unspecified
0.784 0.216 0.000
L71 Rosacea
0.783 0.217 0.000
C34 Malignant neoplasm of bronchus and lung
0.783 0.217 0.000
S51 Open wound of forearm
0.782 0.218 0.000
G20-G26 Extrapyramidal and movement disorders
0.781 0.219 0.000
W19 Unspecified fall
0.778 0.222 0.000
C83.3 Large cell (diffuse)
0.777 0.223 0.000
H26.8 Other specified cataract
0.777 0.223 0.000
L27 Dermatitis due to substances taken internally
0.776 0.224 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.774 0.226 0.000
C91 Lymphoid leukaemia
0.774 0.226 0.000
Y43 Primarily systemic agents
0.772 0.228 0.000
G90-G99 Other disorders of the nervous system
0.772 0.228 0.000
Y57 Other and unspecified drugs and medicaments
0.769 0.231 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.767 0.232 0.000
D72 Other disorders of white blood cells
0.767 0.233 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.767 0.233 0.000
H26.1 Traumatic cataract
0.766 0.234 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.766 0.234 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.766 0.234 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.764 0.236 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.761 0.238 0.000
D46.9 Myelodysplastic syndrome, unspecified
0.761 0.239 0.000
E86 Volume depletion
0.756 0.244 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.755 0.245 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.755 0.245 0.000
M80-M85 Disorders of bone density and structure
0.754 0.245 0.000
M54.3 Sciatica
0.754 0.246 0.000
I49.5 Sick sinus syndrome
0.752 0.248 0.000
M51 Other intervertebral disk disorders
0.751 0.249 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.750 0.250 0.000
Z04 Examination and observation for other reasons
0.749 0.251 0.000
Chapter XXII Codes for special purposes
0.748 0.251 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.748 0.251 0.000
S81.0 Open wound of knee
0.748 0.252 0.000
Q60-Q64 Congenital malformations of the urinary system
0.745 0.255 0.000
I45 Other conduction disorders
0.745 0.255 0.000
M54.4 Lumbago with sciatica
0.744 0.256 0.000
I61 Intracerebral haemorrhage
0.744 0.256 0.000
I50.1 Left ventricular failure
0.744 0.256 0.000
E89.0 Postprocedural hypothyroidism
0.743 0.256 0.000
E87.2 Acidosis
0.743 0.257 0.000
H43-H45 Disorders of vitreous body and globe
0.740 0.260 0.000
S50.9 Superficial injury of forearm, unspecified
0.740 0.260 0.000
I33 Acute and subacute endocarditis
0.740 0.260 0.000
L73 Other follicular disorders
0.739 0.261 0.000
S82.60 Fracture of lateral malleolus (closed)
0.739 0.261 0.000
S89 Other and unspecified injuries of lower leg
0.738 0.262 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.737 0.263 0.000
H26.2 Complicated cataract
0.737 0.263 0.000
I44.2 Atrioventricular block, complete
0.736 0.264 0.000
S81.8 Open wound of other parts of lower leg
0.736 0.264 0.000
I10-I15 Hypertensive diseases
0.736 0.264 0.000
Z12.1 Special screening examination for neoplasm of intestinal tract
0.735 0.265 0.000
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities
0.735 0.265 0.000
G30-G32 Other degenerative diseases of the nervous system
0.734 0.265 0.000
I86 Varicose veins of other sites
0.733 0.267 0.000
E87.7 Fluid overload
0.732 0.268 0.000
I85 Oesophageal varices
0.731 0.269 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.731 0.269 0.000
M00-M03 Infectious arthropathies
0.730 0.269 0.000
I35 Nonrheumatic aortic valve disorders
0.730 0.270 0.000
M19.90 Arthrosis, unspecified (Multiple sites)
0.730 0.270 0.000
D73 Diseases of spleen
0.730 0.270 0.000
H53-H54 Visual disturbances and blindness
0.729 0.271 0.000
G35 Multiple sclerosis
0.729 0.271 0.000
C80 Malignant neoplasm without specification of site
0.728 0.272 0.000
M13.93 Arthritis, unspecified (Forearm)
0.728 0.272 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.728 0.272 0.000
W19.9 Unspecified place
0.725 0.275 0.000
Y40 Systemic antibiotics
0.725 0.275 0.000
M91-M94 Chondropathies
0.724 0.275 0.000
I27 Other pulmonary heart diseases
0.722 0.278 0.000
I44.6 Other and unspecified fascicular block
0.721 0.279 0.000
M11 Other crystal arthropathies
0.721 0.279 0.000
H10-H13 Disorders of conjunctiva
0.719 0.281 0.000
M13.97 Arthritis, unspecified (Ankle and foot)
0.719 0.281 0.000
C77.1 Intrathoracic lymph nodes
0.718 0.282 0.000
M54.1 Radiculopathy
0.717 0.282 0.000
Z08.7 Follow-up examination after combined treatment for malignant neoplasm
0.717 0.283 0.000
L30.9 Dermatitis, unspecified
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
L29.0 Pruritus ani
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.717 0.283 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.717 0.283 0.000
T33-T35 Frostbite
0.716 0.284 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.716 0.284 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.716 0.284 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.716 0.284 0.000
T00-T07 Injuries involving multiple body regions
0.716 0.284 0.000
S10-S19 Injuries to the neck
0.716 0.284 0.000
S00-S09 Injuries to the head
0.716 0.284 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.716 0.284 0.000
T79-T79 Certain early complications of trauma
0.715 0.285 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.715 0.285 0.000
C95 Leukaemia of unspecified cell type
0.715 0.285 0.000
C94 Other leukaemias of specified cell type
0.715 0.285 0.000
C93 Monocytic leukaemia
0.715 0.285 0.000
C88 Malignant immunoproliferative diseases
0.715 0.285 0.000
C86 Other specified types of T/NK-cell lymphoma
0.715 0.285 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.715 0.285 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.714 0.286 0.000
E11 Non-insulin-dependent diabetes mellitus
0.714 0.286 0.000
E40-E46 Malnutrition
0.714 0.286 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.714 0.286 0.000
M54.2 Cervicalgia
0.713 0.287 0.000
T18 Foreign body in alimentary tract
0.713 0.287 0.000
I84.5 External haemorrhoids without complication
0.712 0.288 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.711 0.289 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.710 0.290 0.000
S88 Traumatic amputation of lower leg
0.710 0.290 0.000
S87 Crushing injury of lower leg
0.710 0.290 0.000
S86 Injury of muscle and tendon at lower leg level
0.710 0.290 0.000
S85 Injury of blood vessels at lower leg level
0.710 0.290 0.000
S84 Injury of nerves at lower leg level
0.710 0.290 0.000
I88 Nonspecific lymphadenitis
0.710 0.290 0.000
I81 Portal vein thrombosis
0.710 0.290 0.000
D55-D59 Haemolytic anaemias
0.709 0.290 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.709 0.291 0.000
Z03 Medical observation and evaluation for suspected diseases and conditions
0.709 0.291 0.000
M14 Arthropathies in other diseases classified elsewhere
0.709 0.291 0.000
M12 Other specific arthropathies
0.709 0.291 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.709 0.291 0.000
M08 Juvenile arthritis
0.709 0.291 0.000
M05 Seropositive rheumatoid arthritis
0.709 0.291 0.000
C64-C68 Malignant neoplasms of urinary tract
0.709 0.291 0.000
I52 Other heart disorders in diseases classified elsewhere
0.708 0.292 0.000
I48 Atrial fibrillation and flutter
0.708 0.292 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.708 0.292 0.000
I41 Myocarditis in diseases classified elsewhere
0.708 0.292 0.000
I40 Acute myocarditis
0.708 0.292 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.708 0.292 0.000
I37 Pulmonary valve disorders
0.708 0.292 0.000
I36 Nonrheumatic tricuspid valve disorders
0.708 0.292 0.000
I32 Pericarditis in diseases classified elsewhere
0.708 0.292 0.000
E87.0 Hyperosmolality and hypernatraemia
0.708 0.292 0.000
S82.4 Fracture of fibula alone
0.708 0.292 0.000
W13 Fall from, out of or through building or structure
0.707 0.292 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.707 0.293 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.707 0.293 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.707 0.293 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.707 0.293 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.707 0.293 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.707 0.293 0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.706 0.294 0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.706 0.294 0.000
C85.0 Lymphosarcoma
0.706 0.294 0.000
T31 Burns classified according to extent of body surface involved
0.706 0.294 0.000
E83 Disorders of mineral metabolism
0.706 0.294 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.705 0.294 0.000
D74 Methaemoglobinaemia
0.705 0.294 0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.705 0.294 0.000
D71 Functional disorders of polymorphonuclear neutrophils
0.705 0.294 0.000
I67 Other cerebrovascular diseases
0.705 0.295 0.000
I84.0 Internal thrombosed haemorrhoids
0.705 0.295 0.000
I84.1 Internal haemorrhoids with other complications
0.705 0.295 0.000
L10-L14 Bullous disorders
0.704 0.296 0.000
E21.0 Primary hyperparathyroidism
0.704 0.296 0.000
I62 Other nontraumatic intracranial haemorrhage
0.704 0.296 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.703 0.297 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.703 0.297 0.000
M50.0 Cervical disk disorder with myelopathy
0.703 0.297 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.702 0.298 0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified
0.700 0.300 0.000
M53 Other dorsopathies, not elsewhere classified
0.700 0.300 0.000
S82.5 Fracture of medial malleolus
0.700 0.300 0.000
S80.9 Superficial injury of lower leg, unspecified
0.700 0.300 0.000
S82.0 Fracture of patella
0.699 0.300 0.000
D80-D89 Certain disorders involving the immune mechanism
0.699 0.300 0.000
Chapter X Diseases of the respiratory system
0.699 0.301 0.000
I30 Acute pericarditis
0.699 0.301 0.000
Chapter VIII Diseases of the ear and mastoid process
0.698 0.301 0.000
M13.8 Other specified arthritis
0.698 0.302 0.000
M13.1 Monoarthritis, not elsewhere classified
0.698 0.302 0.000
M13.0 Polyarthritis, unspecified
0.698 0.302 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.696 0.303 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.695 0.305 0.000
M54.6 Pain in thoracic spine
0.694 0.306 0.000
S70-S79 Injuries to the hip and thigh
0.694 0.306 0.000
S59 Other and unspecified injuries of forearm
0.692 0.308 0.000
S58 Traumatic amputation of forearm
0.692 0.308 0.000
S57 Crushing injury of forearm
0.692 0.308 0.000
S56 Injury of muscle and tendon at forearm level
0.692 0.308 0.000
S55 Injury of blood vessels at forearm level
0.692 0.308 0.000
S54 Injury of nerves at forearm level
0.692 0.308 0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow
0.692 0.308 0.000
M13.92 Arthritis, unspecified (Upper arm)
0.691 0.309 0.000
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified
0.690 0.310 0.000
B95-B98 Bacterial, viral and other infectious agents
0.689 0.311 0.000
G25 Other extrapyramidal and movement disorders
0.689 0.311 0.000
E85 Amyloidosis
0.689 0.311 0.000
E84 Cystic fibrosis
0.689 0.311 0.000
E79 Disorders of purine and pyrimidine metabolism
0.689 0.311 0.000
E77 Disorders of glycoprotein metabolism
0.689 0.311 0.000
E76 Disorders of glycosaminoglycan metabolism
0.689 0.311 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.689 0.311 0.000
E74 Other disorders of carbohydrate metabolism
0.689 0.311 0.000
E73 Lactose intolerance
0.689 0.311 0.000
E72 Other disorders of amino-acid metabolism
0.689 0.311 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.689 0.311 0.000
E70 Disorders of aromatic amino-acid metabolism
0.689 0.311 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.689 0.311 0.000
L50-L54 Urticaria and erythema
0.688 0.312 0.000
I60.9 Subarachnoid haemorrhage, unspecified
0.688 0.312 0.000
L75 Apocrine sweat disorders
0.687 0.313 0.000
L74 Eccrine sweat disorders
0.687 0.313 0.000
L70 Acne
0.687 0.313 0.000
L68 Hypertrichosis
0.687 0.313 0.000
L67 Hair colour and hair shaft abnormalities
0.687 0.313 0.000
L66 Cicatricial alopecia [scarring hair loss]
0.687 0.313 0.000
L65 Other nonscarring hair loss
0.687 0.313 0.000
L64 Androgenic alopecia
0.687 0.313 0.000
L63 Alopecia areata
0.687 0.313 0.000
L62 Nail disorders in diseases classified elsewhere
0.687 0.313 0.000
D60-D64 Aplastic and other anaemias
0.686 0.314 0.000
Y43.3 Other antineoplastic drugs
0.685 0.315 0.000
Z12.5 Special screening examination for neoplasm of prostate
0.684 0.316 0.000
S82.9 Fracture of lower leg, part unspecified
0.684 0.316 0.000
S82.7 Multiple fractures of lower leg
0.684 0.316 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.684 0.316 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.682 0.318 0.000
H55 Nystagmus and other irregular eye movements
0.682 0.318 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.681 0.319 0.000
E10 Insulin-dependent diabetes mellitus
0.681 0.319 0.000
E87.4 Mixed disorder of acid-base balance
0.681 0.319 0.000
E87.3 Alkalosis
0.681 0.319 0.000
L29.9 Pruritus, unspecified
0.681 0.319 0.000
C92 Myeloid leukaemia
0.681 0.319 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.680 0.320 0.000
Y57.9 Drug or medicament, unspecified
0.680 0.320 0.000
M10 Gout
0.679 0.321 0.000
I63.9 Cerebral infarction, unspecified
0.679 0.321 0.000
M50.1 Cervical disk disorder with radiculopathy
0.678 0.322 0.000
G70-G73 Diseases of myoneural junction and muscle
0.677 0.323 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.677 0.323 0.000
M19.97 Arthrosis, unspecified (Ankle and foot)
0.676 0.324 0.000
C81.9 Hodgkin's disease, unspecified
0.676 0.324 0.000
M65-M68 Disorders of synovium and tendon
0.676 0.324 0.000
H57 Other disorders of eye and adnexa
0.675 0.325 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.675 0.325 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.675 0.325 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.675 0.325 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.675 0.325 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.675 0.325 0.000
C61 Malignant neoplasm of prostate
0.674 0.326 0.000
L60.9 Nail disorder, unspecified
0.673 0.327 0.000
L60.5 Yellow nail syndrome
0.673 0.327 0.000
L60.4 Beau's lines
0.673 0.327 0.000
L60.3 Nail dystrophy
0.673 0.327 0.000
L60.2 Onychogryphosis
0.673 0.327 0.000
L60.1 Onycholysis
0.673 0.327 0.000
D37.4 Colon
0.673 0.327 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.673 0.327 0.000
L28 Lichen simplex chronicus and prurigo
0.673 0.327 0.000
L25 Unspecified contact dermatitis
0.673 0.327 0.000
L24 Irritant contact dermatitis
0.673 0.327 0.000
L23 Allergic contact dermatitis
0.673 0.327 0.000
L21 Seborrhoeic dermatitis
0.673 0.327 0.000
L20 Atopic dermatitis
0.673 0.327 0.000
L26 Exfoliative dermatitis
0.673 0.327 0.000
L22 Diaper [napkin] dermatitis
0.673 0.327 0.000
I87 Other disorders of veins
0.672 0.328 0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.672 0.328 0.000
M13.95 Arthritis, unspecified (Pelvic region and thigh)
0.672 0.328 0.000
H28 Cataract and other disorders of lens in diseases classified elsewhere
0.671 0.329 0.000
H27 Other disorders of lens
0.671 0.329 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.670 0.330 0.000
A30-A49 Other bacterial diseases
0.670 0.330 0.000
D75.1 Secondary polycythaemia
0.669 0.331 0.000
C34.1 Upper lobe, bronchus or lung
0.668 0.332 0.000
D45 Polycythaemia vera
0.666 0.333 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.666 0.334 0.000
Y35-Y36 Legal intervention and operations of war
0.666 0.334 0.000
Y10-Y34 Event of undetermined intent
0.666 0.334 0.000
Y00-Y09 Assault
0.666 0.334 0.000
X85-X99 Assault
0.666 0.334 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.666 0.334 0.000
X50-X57 Overexertion, travel and privation
0.666 0.334 0.000
X30-X39 Exposure to forces of nature
0.666 0.334 0.000
X20-X29 Contact with venomous animals and plants
0.666 0.334 0.000
X10-X19 Contact with heat and hot substances
0.666 0.334 0.000
X00-X09 Exposure to smoke, fire and flames
0.666 0.334 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.666 0.334 0.000
W75-W84 Other accidental threats to breathing
0.666 0.334 0.000
W65-W74 Accidental drowning and submersion
0.666 0.334 0.000
W50-W64 Exposure to animate mechanical forces
0.666 0.334 0.000
V98-V99 Other and unspecified transport accidents
0.666 0.334 0.000
V95-V97 Air and space transport accidents
0.666 0.334 0.000
V90-V94 Water transport accidents
0.666 0.334 0.000
V80-V89 Other land transport accidents
0.666 0.334 0.000
V70-V79 Bus occupant injured in transport accident
0.666 0.334 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.666 0.334 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.666 0.334 0.000
V40-V49 Car occupant injured in transport accident
0.666 0.334 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.666 0.334 0.000
V01-V09 Pedestrian injured in transport accident
0.666 0.334 0.000
M15 Polyarthrosis
0.666 0.334 0.000
M13.98 Arthritis, unspecified (Other)
0.665 0.335 0.000
I12 Hypertensive renal disease
0.664 0.336 0.000
I49.4 Other and unspecified premature depolarisation
0.663 0.337 0.000
E50-E64 Other nutritional deficiencies
0.662 0.338 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.662 0.338 0.000
M47 Spondylosis
0.661 0.339 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.661 0.339 0.000
M21 Other acquired deformities of limbs
0.660 0.340 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.659 0.341 0.000
L27.0 Generalised skin eruption due to drugs and medicaments
0.659 0.341 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.659 0.341 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.658 0.342 0.000
L71.9 Rosacea, unspecified
0.658 0.342 0.000
X60-X84 Intentional self-harm
0.656 0.344 0.000
M07 Psoriatic and enteropathic arthropathies
0.655 0.345 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.655 0.345 0.000
M89 Other disorders of bone
0.655 0.345 0.000
M86 Osteomyelitis
0.655 0.345 0.000
H26.3 Drug-induced cataract
0.654 0.345 0.000
H26.0 Infantile, juvenile and presenile cataract
0.654 0.345 0.000
S82.86 Maisonneuve's fracture
0.654 0.345 0.000
S82.81 Fractures of other parts of lower leg (open)
0.654 0.345 0.000
S51.8 Open wound of other parts of forearm
0.654 0.346 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.653 0.347 0.000
I82.8 Embolism and thrombosis of other specified veins
0.653 0.347 0.000
M20 Acquired deformities of fingers and toes
0.653 0.347 0.000
V20-V29 Motorcycle rider injured in transport accident
0.652 0.348 0.000
H25 Senile cataract
0.652 0.348 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.650 0.350 0.000
I42 Cardiomyopathy
0.650 0.350 0.000
S82.2 Fracture of shaft of tibia
0.649 0.351 0.000
Z74 Problems related to care-provider dependency
0.649 0.351 0.000
C50-C50 Malignant neoplasm of breast
0.649 0.351 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.648 0.352 0.000
D37.0 Lip, oral cavity and pharynx
0.648 0.352 0.000
S29 Other and unspecified injuries of thorax
0.647 0.353 0.000
M13.91 Arthritis, unspecified (Shoulder region)
0.647 0.353 0.000
M17 Gonarthrosis [arthrosis of knee]
0.646 0.354 0.000
H52 Disorders of refraction and accommodation
0.646 0.354 0.000
S80.8 Other superficial injuries of lower leg
0.645 0.355 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.644 0.356 0.000
C79.6 Secondary malignant neoplasm of ovary
0.644 0.356 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.644 0.356 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.644 0.356 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.644 0.356 0.000
S52.1 Fracture of upper end of radius
0.644 0.356 0.000
M54.8 Other dorsalgia
0.644 0.356 0.000
M54.0 Panniculitis affecting regions of neck and back
0.644 0.356 0.000
G95 Other diseases of spinal cord
0.643 0.356 0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards
0.643 0.357 0.000
Z10 Routine general health check-up of defined subpopulation
0.641 0.358 0.000
D00-D09 In situ neoplasms
0.641 0.359 0.000
Y59 Other and unspecified vaccines and biological substances
0.641 0.359 0.000
Y58 Bacterial vaccines
0.641 0.359 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.641 0.359 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.641 0.359 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.641 0.359 0.000
Y52 Agents primarily affecting the cardiovascular system
0.641 0.359 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.641 0.359 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.641 0.359 0.000
Y48 Anaesthetics and therapeutic gases
0.641 0.359 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.641 0.359 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.641 0.359 0.000
Y44 Agents primarily affecting blood constituents
0.641 0.359 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.641 0.359 0.000
S27 Injury of other and unspecified intrathoracic organs
0.641 0.359 0.000
E22 Hyperfunction of pituitary gland
0.640 0.360 0.000
M19.1 Posttraumatic arthrosis of other joints
0.640 0.360 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.639 0.360 0.000
M54.36 Sciatica (Lumbar region)
0.639 0.361 0.000
M19.8 Other specified arthrosis
0.639 0.361 0.000
M19.2 Other secondary arthrosis
0.639 0.361 0.000
E28 Ovarian dysfunction
0.639 0.361 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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