TreeWAS – Variant ID: rs115515529

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	1.000	0.000	0.000
# Top node	1.000	0.000	0.000
Chapter II Neoplasms	1.000	0.000	0.000
D10-D36 Benign neoplasms	1.000	0.000	0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal	1.000	0.000	0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.999	0.001	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.996	0.004	0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems	0.996	0.004	0.000
Chapter XXI Factors influencing health status and contact with health services	0.995	0.005	0.000
Chapter VII Diseases of the eye and adnexa	0.991	0.009	0.000
D25 Leiomyoma of uterus	0.989	0.011	0.000
R41 Other symptoms and signs involving cognitive functions and awareness	0.988	0.012	0.000
D25.9 Leiomyoma of uterus, unspecified	0.986	0.014	0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status	0.985	0.015	0.000
D12.5 Sigmoid colon	0.985	0.015	0.000
Chapter X Diseases of the respiratory system	0.984	0.016	0.000
J40-J47 Chronic lower respiratory diseases	0.977	0.023	0.000
D12.2 Ascending colon	0.976	0.024	0.000
Chapter VI Diseases of the nervous system	0.975	0.025	0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances	0.974	0.026	0.000
R50-R69 General symptoms and signs	0.974	0.026	0.000
R00 Abnormalities of heart beat	0.968	0.032	0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.964	0.036	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.958	0.042	0.000
J44 Other chronic obstructive pulmonary disease	0.956	0.044	0.000
D12.3 Transverse colon	0.949	0.051	0.000
R00.0 Tachycardia, unspecified	0.943	0.057	0.000
D12.4 Descending colon	0.942	0.058	0.000
Z88.6 Personal history of allergy to analgesic agent	0.937	0.063	0.000
R41.0 Disorientation, unspecified	0.936	0.064	0.000
Z70-Z76 Persons encountering health services in other circumstances	0.935	0.065	0.000
Z87 Personal history of other diseases and conditions	0.932	0.068	0.000
R42 Dizziness and giddiness	0.930	0.070	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.918	0.082	0.000
J45 Asthma	0.906	0.094	0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.906	0.094	0.000
H04 Disorders of lachrymal system	0.902	0.098	0.000
R44 Other symptoms and signs involving general sensations and perceptions	0.900	0.100	0.000
Z00-Z13 Persons encountering health services for examination and investigation	0.897	0.103	0.000
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness	0.896	0.104	0.000
H30-H36 Disorders of choroid and retina	0.892	0.108	0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.891	0.109	0.000
Z87.3 Personal history of diseases of the musculoskeletal system and connective tissue	0.890	0.110	0.000
G40-G47 Episodic and paroxysmal disorders	0.885	0.115	0.000
Chapter XX External causes of morbidity and mortality	0.885	0.115	0.000
Z91 Personal history of risk-factors, not elsewhere classified	0.882	0.118	0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems	0.880	0.120	0.000
J44.8 Other specified chronic obstructive pulmonary disease	0.878	0.122	0.000
G90-G99 Other disorders of the nervous system	0.876	0.124	0.000
H00 Hordeolum and chalazion	0.875	0.125	0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis	0.873	0.127	0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified	0.871	0.129	0.000
R06 Abnormalities of breathing	0.870	0.130	0.000
Z88.5 Personal history of allergy to narcotic agent	0.867	0.133	0.000
Z95 Presence of cardiac and vascular implants and grafts	0.863	0.137	0.000
R45 Symptoms and signs involving emotional state	0.863	0.137	0.000
R41.3 Other amnesia	0.862	0.138	0.000
R55 Syncope and collapse	0.862	0.138	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.854	0.146	0.000
C50-C50 Malignant neoplasm of breast	0.851	0.149	0.000
T39.1 4-Aminophenol derivatives	0.849	0.151	0.000
R05 Cough	0.848	0.152	0.000
J42 Unspecified chronic bronchitis	0.846	0.153	0.000
Z72 Problems related to lifestyle	0.842	0.158	0.000
S60-S69 Injuries to the wrist and hand	0.841	0.159	0.000
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms	0.840	0.160	0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.840	0.160	0.000
S20-S29 Injuries to the thorax	0.838	0.162	0.000
D34 Benign neoplasm of thyroid gland	0.838	0.162	0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen	0.836	0.164	0.000
H04.5 Stenosis and insufficiency of lachrymal passages	0.835	0.165	0.000
C51-C58 Malignant neoplasms of female genital organs	0.835	0.165	0.000
D12.7 Rectosigmoid junction	0.834	0.166	0.000
J44.9 Chronic obstructive pulmonary disease, unspecified	0.834	0.166	0.000
Z94 Transplanted organ and tissue status	0.832	0.168	0.000
S00-S09 Injuries to the head	0.832	0.168	0.000
D35 Benign neoplasm of other and unspecified endocrine glands	0.832	0.168	0.000
R60 Oedema, not elsewhere classified	0.829	0.171	0.000
R47-R49 Symptoms and signs involving speech and voice	0.827	0.173	0.000
H52 Disorders of refraction and accommodation	0.826	0.174	0.000
R53 Malaise and fatigue	0.825	0.175	0.000
J90-J94 Other diseases of pleura	0.825	0.175	0.000
D37-D48 Neoplasms of uncertain or unknown behaviour	0.818	0.182	0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement	0.817	0.183	0.000
Z88.2 Personal history of allergy to sulphonamides	0.814	0.185	0.000
Chapter XIV Diseases of the genitourinary system	0.813	0.187	0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.813	0.187	0.000
Chapter V Mental and behavioural disorders	0.812	0.188	0.000
H01 Other inflammation of eyelid	0.811	0.189	0.000
Z88.0 Personal history of allergy to penicillin	0.811	0.189	0.000
R52 Pain, not elsewhere classified	0.811	0.189	0.000
H00.1 Chalazion	0.811	0.189	0.000
N80-N98 Noninflammatory disorders of female genital tract	0.809	0.191	0.000
J45.0 Predominantly allergic asthma	0.808	0.192	0.000
Z87.7 Personal history of congenital malformations, deformations and chromosomal abnormalities	0.807	0.192	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.807	0.193	0.000
Chapter VIII Diseases of the ear and mastoid process	0.806	0.194	0.000
Z91.0 Personal history of allergy, other than to drugs and biological substances	0.805	0.195	0.000
R18 Ascites	0.804	0.196	0.000
Chapter XI Diseases of the digestive system	0.804	0.196	0.000
R03 Abnormal blood-pressure reading, without diagnosis	0.801	0.199	0.000
Z87.8 Personal history of other specified conditions	0.799	0.201	0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.798	0.202	0.000
R94 Abnormal results of function studies	0.797	0.203	0.000
G40 Epilepsy	0.795	0.205	0.000
J00-J06 Acute upper respiratory infections	0.794	0.206	0.000
R68 Other general symptoms and signs	0.794	0.206	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.793	0.207	0.000
R56 Convulsions, not elsewhere classified	0.792	0.208	0.000
Z83 Family history of other specific disorders	0.792	0.208	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.792	0.208	0.000
G41 Status epilepticus	0.791	0.209	0.000
R02 Gangrene, not elsewhere classified	0.791	0.209	0.000
Z87.0 Personal history of diseases of the respiratory system	0.789	0.211	0.000
R63 Symptoms and signs concerning food and fluid intake	0.787	0.213	0.000
G30-G32 Other degenerative diseases of the nervous system	0.786	0.214	0.000
J60-J70 Lung diseases due to external agents	0.783	0.217	0.000
R58 Haemorrhage, not elsewhere classified	0.782	0.218	0.000
G20-G26 Extrapyramidal and movement disorders	0.782	0.218	0.000
Z75 Problems related to medical facilities and other health care	0.782	0.218	0.000
R00.1 Bradycardia, unspecified	0.781	0.219	0.000
Z95.4 Presence of other heart-valve replacement	0.780	0.220	0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue	0.780	0.220	0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.780	0.220	0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified	0.779	0.221	0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.778	0.222	0.000
C43-C44 Melanoma and other malignant neoplasms of skin	0.776	0.224	0.000
T39.0 Salicylates	0.776	0.224	0.000
D10 Benign neoplasm of mouth and pharynx	0.775	0.224	0.000
G00-G09 Inflammatory diseases of the central nervous system	0.774	0.226	0.000
J45.9 Asthma, unspecified	0.773	0.227	0.000
C83 Diffuse non-Hodgkin's lymphoma	0.772	0.228	0.000
H53-H54 Visual disturbances and blindness	0.769	0.231	0.000
H34 Retinal vascular occlusions	0.766	0.234	0.000
G93 Other disorders of brain	0.766	0.234	0.000
R15 Faecal incontinence	0.766	0.234	0.000
D26 Other benign neoplasms of uterus	0.766	0.234	0.000
R44.1 Visual hallucinations	0.766	0.234	0.000
Z03 Medical observation and evaluation for suspected diseases and conditions	0.764	0.236	0.000
H55-H59 Other disorders of eye and adnexa	0.764	0.236	0.000
Y95 Nosocomial condition	0.762	0.238	0.000
N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament	0.762	0.238	0.000
H52.1 Myopia	0.761	0.239	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.761	0.239	0.000
D21 Other benign neoplasms of connective and other soft tissue	0.761	0.239	0.000
Z09.0 Follow-up examination after surgery for other conditions	0.761	0.239	0.000
R06.8 Other and unspecified abnormalities of breathing	0.760	0.240	0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.759	0.241	0.000
K35-K38 Diseases of appendix	0.759	0.241	0.000
D23 Other benign neoplasms of skin	0.758	0.242	0.000
R94.5 Abnormal results of liver function studies	0.758	0.242	0.000
Z72.1 Alcohol use	0.757	0.243	0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.756	0.244	0.000
R09.1 Pleurisy	0.755	0.245	0.000
H35 Other retinal disorders	0.754	0.246	0.000
S50-S59 Injuries to the elbow and forearm	0.753	0.247	0.000
R17 Unspecified jaundice	0.752	0.248	0.000
N90 Other noninflammatory disorders of vulva and perineum	0.752	0.248	0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.751	0.249	0.000
R61 Hyperhidrosis	0.750	0.250	0.000
S90-S99 Injuries to the ankle and foot	0.750	0.250	0.000
S80-S89 Injuries to the knee and lower leg	0.750	0.250	0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.749	0.250	0.000
S40-S49 Injuries to the shoulder and upper arm	0.749	0.251	0.000
Z89 Acquired absence of limb	0.748	0.252	0.000
R57 Shock, not elsewhere classified	0.748	0.252	0.000
S02 Fracture of skull and facial bones	0.747	0.253	0.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system	0.746	0.254	0.000
R04 Haemorrhage from respiratory passages	0.745	0.254	0.001
C50 Malignant neoplasm of breast	0.744	0.256	0.000
R44.0 Auditory hallucinations	0.742	0.258	0.000
K70-K77 Diseases of liver	0.741	0.259	0.000
N89 Other noninflammatory disorders of vagina	0.740	0.260	0.000
Z08 Follow-up examination after treatment for malignant neoplasm	0.740	0.260	0.000
Chapter I Certain infectious and parasitic diseases	0.739	0.260	0.000
H04.3 Acute and unspecified inflammation of lachrymal passages	0.739	0.261	0.000
Z88.8 Personal history of allergy to other drugs, medicaments and biological substances	0.738	0.262	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.737	0.263	0.000
Z97 Presence of other devices	0.735	0.264	0.000
T66-T78 Other and unspecified effects of external causes	0.734	0.266	0.000
Z95.8 Presence of other cardiac and vascular implants and grafts	0.733	0.267	0.000
G80-G83 Cerebral palsy and other paralytic syndromes	0.732	0.268	0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.732	0.268	0.000
S70-S79 Injuries to the hip and thigh	0.731	0.269	0.000
R03.1 Nonspecific low blood-pressure reading	0.730	0.270	0.000
D12.8 Rectum	0.730	0.270	0.000
R09.2 Respiratory arrest	0.729	0.270	0.000
R60.0 Localised oedema	0.729	0.271	0.000
K35 Acute appendicitis	0.729	0.271	0.000
R00.8 Other and unspecified abnormalities of heart beat	0.729	0.271	0.000
D32 Benign neoplasm of meninges	0.728	0.271	0.000
N85 Other noninflammatory disorders of uterus, except cervix	0.728	0.272	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.727	0.273	0.000
N80 Endometriosis	0.726	0.274	0.000
J95-J99 Other diseases of the respiratory system	0.725	0.274	0.000
Chapter XXII Codes for special purposes	0.725	0.275	0.000
G41.9 Status epilepticus, unspecified	0.724	0.276	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.721	0.279	0.000
E70-E90 Metabolic disorders	0.721	0.279	0.000
S64 Injury of nerves at wrist and hand level	0.718	0.282	0.000
H49 Paralytic strabismus	0.718	0.282	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.717	0.283	0.000
R95-R99 Ill-defined and unknown causes of mortality	0.717	0.283	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283	0.000
D31 Benign neoplasm of eye and adnexa	0.717	0.283	0.000
D30 Benign neoplasm of urinary organs	0.717	0.283	0.000
D29 Benign neoplasm of male genital organs	0.717	0.283	0.000
D28 Benign neoplasm of other and unspecified female genital organs	0.717	0.283	0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum	0.717	0.283	0.000
D19 Benign neoplasm of mesothelial tissue	0.717	0.283	0.000
D16 Benign neoplasm of bone and articular cartilage	0.717	0.283	0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs	0.717	0.283	0.000
D14 Benign neoplasm of middle ear and respiratory system	0.717	0.283	0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.717	0.283	0.000
C40-C41 Malignant neoplasms of bone and articular cartilage	0.717	0.283	0.000
D12.9 Anus and anal canal	0.717	0.283	0.000
D12.1 Appendix	0.717	0.283	0.000
R46 Symptoms and signs involving appearance and behaviour	0.716	0.283	0.000
R43 Disturbances of smell and taste	0.716	0.283	0.000
Chapter XV Pregnancy, childbirth and the puerperium	0.715	0.285	0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.715	0.285	0.000
T79-T79 Certain early complications of trauma	0.714	0.286	0.000
T33-T35 Frostbite	0.714	0.286	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.714	0.286	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.714	0.286	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.714	0.286	0.000
T00-T07 Injuries involving multiple body regions	0.714	0.286	0.000
S10-S19 Injuries to the neck	0.714	0.286	0.000
R45.1 Restlessness and agitation	0.714	0.286	0.000
Z03.8 Observation for other suspected diseases and conditions	0.713	0.287	0.000
G44 Other headache syndromes	0.713	0.287	0.000
H46-H48 Disorders of optic nerve and visual pathways	0.710	0.289	0.000
H10-H13 Disorders of conjunctiva	0.710	0.289	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.710	0.290	0.000
R47 Speech disturbances, not elsewhere classified	0.710	0.290	0.000
R41.2 Retrograde amnesia	0.709	0.291	0.000
R41.1 Anterograde amnesia	0.709	0.291	0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.707	0.293	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.707	0.293	0.000
Z84 Family history of other conditions	0.706	0.294	0.000
Z81 Family history of mental and behavioural disorders	0.706	0.294	0.000
Z88.9 Personal history of allergy to unspecified drugs, medicaments and biological substances	0.706	0.294	0.000
F40-F48 Neurotic, stress-related and somatoform disorders	0.705	0.295	0.000
R40 Somnolence, stupor and coma	0.705	0.295	0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes	0.704	0.296	0.000
Z90 Acquired absence of organs, not elsewhere classified	0.704	0.296	0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.704	0.296	0.000
E87 Other disorders of fluid, electrolyte and acid-base balance	0.703	0.297	0.000
Z57 Occupational exposure to risk-factors	0.702	0.298	0.000
H01.0 Blepharitis	0.702	0.298	0.000
M80-M85 Disorders of bone density and structure	0.702	0.298	0.000
R45.8 Other symptoms and signs involving emotional state	0.702	0.298	0.000
W50-W64 Exposure to animate mechanical forces	0.701	0.299	0.000
H04.1 Other disorders of lachrymal gland	0.701	0.299	0.000
J41 Simple and mucopurulent chronic bronchitis	0.700	0.299	0.000
J46 Status asthmaticus	0.700	0.299	0.000
M05-M14 Inflammatory polyarthropathies	0.699	0.301	0.000
G70-G73 Diseases of myoneural junction and muscle	0.699	0.301	0.000
Z88.4 Personal history of allergy to anaesthetic agent	0.698	0.302	0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]	0.698	0.302	0.000
R62 Lack of expected normal physiological development	0.698	0.302	0.000
R64 Cachexia	0.698	0.302	0.000
G90 Disorders of autonomic nervous system	0.698	0.302	0.000
Z04 Examination and observation for other reasons	0.697	0.303	0.000
R06.2 Wheezing	0.696	0.304	0.000
R63.0 Anorexia	0.694	0.306	0.000
S00 Superficial injury of head	0.693	0.307	0.000
H90-H95 Other disorders of ear	0.693	0.307	0.000
Z95.2 Presence of prosthetic heart valve	0.693	0.307	0.000
V40-V49 Car occupant injured in transport accident	0.692	0.308	0.000
Z09.8 Follow-up examination after other treatment for other conditions	0.692	0.308	0.000
D35.1 Parathyroid gland	0.692	0.308	0.000
Z88.7 Personal history of allergy to serum and vaccine	0.692	0.308	0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere	0.691	0.309	0.000
H05 Disorders of orbit	0.691	0.309	0.000
H03 Disorders of eyelid in diseases classified elsewhere	0.691	0.309	0.000
S30 Superficial injury of abdomen, lower back and pelvis	0.691	0.309	0.000
N89.8 Other specified noninflammatory disorders of vagina	0.691	0.309	0.000
Z95.1 Presence of aortocoronary bypass graft	0.691	0.309	0.000
F00-F09 Organic, including symptomatic, mental disorders	0.691	0.309	0.000
C55 Malignant neoplasm of uterus, part unspecified	0.691	0.309	0.000
M65-M68 Disorders of synovium and tendon	0.690	0.310	0.000
Z94.0 Kidney transplant status	0.690	0.310	0.000
R06.5 Mouth breathing	0.687	0.313	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.687	0.313	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.687	0.313	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.687	0.313	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.687	0.313	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.687	0.313	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.687	0.313	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.687	0.313	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.687	0.313	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.687	0.313	0.000
T36 Poisoning by systemic antibiotics	0.687	0.313	0.000
Z87.5 Personal history of complications of pregnancy, childbirth and the puerperium	0.687	0.313	0.000
R04.2 Haemoptysis	0.686	0.314	0.000
G35-G37 Demyelinating diseases of the central nervous system	0.685	0.315	0.000
N83.0 Follicular cyst of ovary	0.685	0.315	0.000
R44.3 Hallucinations, unspecified	0.685	0.315	0.000
J80-J84 Other respiratory diseases principally affecting the interstitium	0.681	0.318	0.000
R50 Fever of unknown origin	0.681	0.319	0.000
Y60-Y69 Misadventures to patients during surgical and medical care	0.681	0.319	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.680	0.320	0.000
C50.9 Breast, unspecified	0.678	0.322	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.677	0.323	0.000
Z09.9 Follow-up examination after unspecified treatment for other conditions	0.677	0.323	0.000
K35.0 Acute appendicitis with generalised peritonitis	0.677	0.323	0.000
V20-V29 Motorcycle rider injured in transport accident	0.676	0.324	0.000
M70-M79 Other soft tissue disorders	0.675	0.325	0.000
S22 Fracture of rib(s), sternum and thoracic spine	0.673	0.326	0.000
M00-M03 Infectious arthropathies	0.673	0.327	0.000
Z91.5 Personal history of self-harm	0.673	0.327	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.672	0.328	0.000
Z75.1 Person awaiting admission to adequate facility elsewhere	0.672	0.328	0.000
R52.1 Chronic intractable pain	0.671	0.329	0.000
Z76 Persons encountering health services in other circumstances	0.670	0.330	0.000
Z70 Counselling related to sexual attitude, behaviour and orientation	0.670	0.330	0.000
D25.2 Subserosal leiomyoma of uterus	0.670	0.330	0.000
K65-K67 Diseases of peritoneum	0.670	0.330	0.000
Z87.6 Personal history of certain conditions arising in the perinatal period	0.668	0.332	0.000
G99 Other disorders of nervous system in diseases classified elsewhere	0.668	0.332	0.000
N83.2 Other and unspecified ovarian cysts	0.667	0.333	0.000
D12.6 Colon, unspecified	0.666	0.334	0.000
D33 Benign neoplasm of brain and other parts of central nervous system	0.666	0.334	0.000
S62 Fracture at wrist and hand level	0.666	0.334	0.000
N92 Excessive, frequent and irregular menstruation	0.665	0.335	0.000
R68.8 Other specified general symptoms and signs	0.665	0.335	0.000
R20 Disturbances of skin sensation	0.663	0.337	0.000
C83.3 Large cell (diffuse)	0.663	0.337	0.000
G96 Other disorders of central nervous system	0.663	0.337	0.000
R54 Senility	0.663	0.337	0.000
S27 Injury of other and unspecified intrathoracic organs	0.663	0.337	0.000
R56.8 Other and unspecified convulsions	0.662	0.338	0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.661	0.339	0.000
D18 Haemangioma and lymphangioma, any site	0.661	0.339	0.000
R90 Abnormal findings on diagnostic imaging of central nervous system	0.661	0.339	0.000
Z88.3 Personal history of allergy to other anti-infective agents	0.659	0.341	0.000
R16 Hepatomegaly and splenomegaly, not elsewhere classified	0.659	0.341	0.000
M86-M90 Other osteopathies	0.658	0.341	0.000
G20 Parkinson's disease	0.659	0.341	0.000
C44 Other malignant neoplasms of skin	0.658	0.342	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.658	0.342	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.658	0.342	0.000
T39.4 Antirheumatics, not elsewhere classified	0.658	0.342	0.000
T39.2 Pyrazolone derivatives	0.658	0.342	0.000
W00-W19 Falls	0.658	0.342	0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.658	0.342	0.000
C56 Malignant neoplasm of ovary	0.658	0.342	0.000
Z71.3 Dietary counselling and surveillance	0.657	0.343	0.000
Z72.0 Tobacco use	0.657	0.343	0.000
N90.8 Other specified noninflammatory disorders of vulva and perineum	0.655	0.345	0.000
H80-H83 Diseases of inner ear	0.655	0.345	0.000
Z03.4 Observation for suspected myocardial infarction	0.655	0.345	0.000
G93.1 Anoxic brain damage, not elsewhere classified	0.655	0.345	0.000
H34.8 Other retinal vascular occlusions	0.654	0.345	0.000
J40 Bronchitis, not specified as acute or chronic	0.654	0.346	0.000
E87.2 Acidosis	0.654	0.346	0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.653	0.347	0.000
S02.4 Fracture of malar and maxillary bones	0.652	0.348	0.000
D11 Benign neoplasm of major salivary glands	0.651	0.349	0.000
Z94.8 Other transplanted organ and tissue status	0.651	0.349	0.000
E88 Other metabolic disorders	0.650	0.350	0.000
J45.8 Mixed asthma	0.649	0.350	0.000
J45.1 Nonallergic asthma	0.649	0.350	0.000
H51 Other disorders of binocular movement	0.649	0.350	0.000
Z08.7 Follow-up examination after combined treatment for malignant neoplasm	0.649	0.351	0.000
Z95.3 Presence of xenogenic heart valve	0.648	0.352	0.000
C92 Myeloid leukaemia	0.648	0.352	0.000
J94 Other pleural conditions	0.648	0.352	0.000
N86 Erosion and ectropion of cervix uteri	0.647	0.353	0.000
H04.9 Disorder of lachrymal system, unspecified	0.647	0.353	0.000
H04.8 Other disorders of lachrymal system	0.647	0.353	0.000
H04.6 Other changes in lachrymal passages	0.647	0.353	0.000
H04.4 Chronic inflammation of lachrymal passages	0.647	0.353	0.000
H04.0 Dacryoadenitis	0.647	0.353	0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type	0.646	0.354	0.000
N85.8 Other specified noninflammatory disorders of uterus	0.646	0.354	0.000
R44.8 Other and unspecified symptoms and signs involving general sensations and perceptions	0.646	0.354	0.000
R44.2 Other hallucinations	0.646	0.354	0.000
J00 Acute nasopharyngitis [common cold]	0.645	0.355	0.000
Z13 Special screening examination for other diseases and disorders	0.645	0.355	0.000
Z10 Routine general health check-up of defined subpopulation	0.643	0.357	0.000
K70 Alcoholic liver disease	0.643	0.357	0.000
R01 Cardiac murmurs and other cardiac sounds	0.643	0.357	0.000
H33 Retinal detachments and breaks	0.643	0.357	0.000
D23.4 Skin of scalp and neck	0.642	0.358	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.641	0.359	0.000
G45 Transient cerebral ischaemic attacks and related syndromes	0.641	0.359	0.000
H32 Chorioretinal disorders in diseases classified elsewhere	0.640	0.360	0.000
H31 Other disorders of choroid	0.640	0.360	0.000
H30 Chorioretinal inflammation	0.640	0.360	0.000
V10-V19 Pedal cyclist injured in transport accident	0.639	0.360	0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.639	0.361	0.000
C91 Lymphoid leukaemia	0.639	0.361	0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.638	0.361	0.000
C95 Leukaemia of unspecified cell type	0.638	0.361	0.000
C94 Other leukaemias of specified cell type	0.638	0.361	0.000
C93 Monocytic leukaemia	0.638	0.361	0.000
C88 Malignant immunoproliferative diseases	0.638	0.361	0.000
C86 Other specified types of T/NK-cell lymphoma	0.638	0.361	0.000
C84 Peripheral and cutaneous T-cell lymphomas	0.638	0.361	0.000
C81 Hodgkin's disease	0.638	0.361	0.000
H52.3 Anisometropia and aniseikonia	0.638	0.362	0.000
Z74 Problems related to care-provider dependency	0.638	0.362	0.000
H50 Other strabismus	0.637	0.363	0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.637	0.363	0.000
E50-E64 Other nutritional deficiencies	0.637	0.363	0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.637	0.363	0.000
H54 Blindness and low vision	0.637	0.363	0.000
J69 Pneumonitis due to solids and liquids	0.636	0.363	0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.635	0.365	0.000
G46 Vascular syndromes of brain in cerebrovascular diseases	0.634	0.365	0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.634	0.366	0.000
Y35-Y36 Legal intervention and operations of war	0.634	0.366	0.000
Y10-Y34 Event of undetermined intent	0.634	0.366	0.000
Y00-Y09 Assault	0.634	0.366	0.000
X85-X99 Assault	0.634	0.366	0.000
X58-X59 Accidental exposure to other and unspecified factors	0.634	0.366	0.000
X50-X57 Overexertion, travel and privation	0.634	0.366	0.000
X40-X49 Accidental poisoning by and exposure to noxious substances	0.634	0.366	0.000
X30-X39 Exposure to forces of nature	0.634	0.366	0.000
X20-X29 Contact with venomous animals and plants	0.634	0.366	0.000
X10-X19 Contact with heat and hot substances	0.634	0.366	0.000
X00-X09 Exposure to smoke, fire and flames	0.634	0.366	0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.634	0.366	0.000
W75-W84 Other accidental threats to breathing	0.634	0.366	0.000
W65-W74 Accidental drowning and submersion	0.634	0.366	0.000
V98-V99 Other and unspecified transport accidents	0.634	0.366	0.000
V95-V97 Air and space transport accidents	0.634	0.366	0.000
V90-V94 Water transport accidents	0.634	0.366	0.000
V80-V89 Other land transport accidents	0.634	0.366	0.000
V70-V79 Bus occupant injured in transport accident	0.634	0.366	0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.634	0.366	0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.634	0.366	0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.634	0.366	0.000
V01-V09 Pedestrian injured in transport accident	0.634	0.366	0.000
G40.9 Epilepsy, unspecified	0.634	0.366	0.000
R93 Abnormal findings on diagnostic imaging of other body structures	0.632	0.368	0.000
Z91.8 Personal history of other specified risk-factors, not elsewhere classified	0.632	0.368	0.000
Z91.7 Personal history of female genital mutilation	0.632	0.368	0.000
Z91.4 Personal history of psychological trauma, not elsewhere classified	0.632	0.368	0.000
Z91.3 Personal history of unhealthy sleep-wake schedule	0.632	0.368	0.000
Z91.2 Personal history of poor personal hygiene	0.632	0.368	0.000
R06.4 Hyperventilation	0.632	0.368	0.000
H36 Retinal disorders in diseases classified elsewhere	0.631	0.369	0.000
G11 Hereditary ataxia	0.631	0.369	0.000
R09.3 Abnormal sputum	0.631	0.369	0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.630	0.370	0.000
Z63 Other problems related to primary support group, including family circumstances	0.630	0.370	0.000
S64.4 Injury of digital nerve of other finger	0.630	0.370	0.000
Z91.6 Personal history of other physical trauma	0.630	0.370	0.000
Z90.3 Acquired absence of part of stomach	0.629	0.371	0.000
D36 Benign neoplasm of other and unspecified sites	0.629	0.371	0.000
Z83.3 Family history of diabetes mellitus	0.628	0.372	0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified	0.628	0.372	0.000
G95 Other diseases of spinal cord	0.628	0.372	0.000
G94 Other disorders of brain in diseases classified elsewhere	0.628	0.372	0.000
G98 Other disorders of nervous system, not elsewhere classified	0.628	0.372	0.000
G92 Toxic encephalopathy	0.628	0.372	0.000
D35.2 Pituitary gland	0.628	0.372	0.000
R82 Other abnormal findings in urine	0.627	0.372	0.000
G12 Spinal muscular atrophy and related syndromes	0.627	0.372	0.000
R09.8 Other specified symptoms and signs involving the circulatory and respiratory systems	0.627	0.373	0.000
H00.0 Hordeolum and other deep inflammation of eyelid	0.627	0.373	0.000
R59 Enlarged lymph nodes	0.627	0.373	0.000
A30-A49 Other bacterial diseases	0.627	0.373	0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis	0.626	0.374	0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.626	0.374	0.000
R92 Abnormal findings on diagnostic imaging of breast	0.626	0.374	0.000
H35.5 Hereditary retinal dystrophy	0.625	0.375	0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis	0.625	0.375	0.000
N80.0 Endometriosis of uterus	0.624	0.376	0.000
J04 Acute laryngitis and tracheitis	0.624	0.376	0.000
R06.7 Sneezing	0.624	0.376	0.000
R06.6 Hiccough	0.624	0.376	0.000
R06.3 Periodic breathing	0.624	0.376	0.000
R06.1 Stridor	0.624	0.376	0.000
K76 Other diseases of liver	0.623	0.377	0.000
M20-M25 Other joint disorders	0.622	0.378	0.000
S61 Open wound of wrist and hand	0.622	0.378	0.000
C09 Malignant neoplasm of tonsil	0.622	0.378	0.000
D23.1 Skin of eyelid, including canthus	0.622	0.378	0.000
N99-N99 Other disorders of the genitourinary system	0.622	0.378	0.000
D13 Benign neoplasm of other and ill-defined parts of digestive system	0.621	0.379	0.000
Z60 Problems related to social environment	0.621	0.379	0.000
J90 Pleural effusion, not elsewhere classified	0.621	0.379	0.000
J92 Pleural plaque	0.620	0.380	0.000
K35.1 Acute appendicitis with peritoneal abscess	0.619	0.381	0.000
C15-C26 Malignant neoplasms of digestive organs	0.619	0.381	0.000
R45.7 State of emotional shock and stress, unspecified	0.618	0.381	0.000
R45.6 Physical violence	0.618	0.381	0.000
R45.5 Hostility	0.618	0.381	0.000
R45.4 Irritability and anger	0.618	0.381	0.000
R45.3 Demoralisation and apathy	0.618	0.381	0.000
R45.2 Unhappiness	0.618	0.381	0.000
R45.0 Nervousness	0.618	0.381	0.000
J91 Pleural effusion in conditions classified elsewhere	0.618	0.381	0.000
Z02 Examination and encounter for administrative purposes	0.618	0.382	0.000
S20 Superficial injury of thorax	0.618	0.382	0.000
J43 Emphysema	0.617	0.383	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations