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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs115523726
log Bayes Factor = 19.6278
Chromosome 5   position 127,412,113  (GRCh37) Explore rs115523726 on Ensembl!
Variant rs115523726 is part of Cluster X0277

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I25 Chronic ischaemic heart disease
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter VI Diseases of the nervous system
0.999 0.001 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.996 0.004 0.000
I10-I15 Hypertensive diseases
0.993 0.007 0.000
I25.2 Old myocardial infarction
0.992 0.008 0.000
G90-G99 Other disorders of the nervous system
0.991 0.009 0.000
Chapter XIV Diseases of the genitourinary system
0.990 0.010 0.000
I30-I52 Other forms of heart disease
0.988 0.012 0.000
I10 Essential (primary) hypertension
0.987 0.013 0.000
I51 Complications and ill-defined descriptions of heart disease
0.985 0.015 0.000
I25.1 Atherosclerotic heart disease
0.984 0.016 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.982 0.018 0.000
N10-N16 Renal tubulo-interstitial diseases
0.979 0.021 0.000
M50-M54 Other dorsopathies
0.979 0.021 0.000
N13 Obstructive and reflux uropathy
0.975 0.025 0.000
C50-C50 Malignant neoplasm of breast
0.975 0.025 0.000
C34 Malignant neoplasm of bronchus and lung
0.973 0.027 0.000
Chapter I Certain infectious and parasitic diseases
0.972 0.028 0.000
I51.7 Cardiomegaly
0.972 0.028 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.972 0.028 0.000
G99.2 Myelopathy in diseases classified elsewhere
0.958 0.042 0.000
C50 Malignant neoplasm of breast
0.957 0.043 0.000
Chapter XX External causes of morbidity and mortality
0.955 0.045 0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction
0.951 0.049 0.000
B95-B98 Bacterial, viral and other infectious agents
0.950 0.050 0.000
N17-N19 Renal failure
0.949 0.051 0.000
D00-D09 In situ neoplasms
0.944 0.056 0.000
C34.9 Bronchus or lung, unspecified
0.943 0.057 0.000
M05-M14 Inflammatory polyarthropathies
0.943 0.057 0.000
C50.9 Breast, unspecified
0.937 0.063 0.000
Chapter X Diseases of the respiratory system
0.937 0.063 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.932 0.068 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.932 0.068 0.000
M20-M25 Other joint disorders
0.931 0.069 0.000
N25-N29 Other disorders of kidney and ureter
0.931 0.069 0.000
N18 Chronic renal failure
0.930 0.070 0.000
M50 Cervical disk disorders
0.930 0.070 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.930 0.070 0.000
I51.9 Heart disease, unspecified
0.927 0.073 0.000
J40-J47 Chronic lower respiratory diseases
0.927 0.073 0.000
N18.3 Chronic kidney disease, stage 3
0.925 0.075 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.923 0.077 0.000
Chapter XXI Factors influencing health status and contact with health services
0.920 0.080 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.916 0.084 0.000
M06 Other rheumatoid arthritis
0.914 0.086 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.913 0.087 0.000
Z95.1 Presence of aortocoronary bypass graft
0.911 0.089 0.000
C34.1 Upper lobe, bronchus or lung
0.909 0.091 0.000
Chapter VII Diseases of the eye and adnexa
0.906 0.094 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.905 0.095 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.904 0.096 0.000
D04 Carcinoma in situ of skin
0.903 0.097 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.903 0.097 0.000
C60-C63 Malignant neoplasms of male genital organs
0.897 0.103 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.893 0.107 0.000
Z85 Personal history of malignant neoplasm
0.893 0.107 0.000
N20-N23 Urolithiasis
0.891 0.109 0.000
I78 Diseases of capillaries
0.891 0.109 0.000
Z85.3 Personal history of malignant neoplasm of breast
0.889 0.111 0.000
I34 Nonrheumatic mitral valve disorders
0.888 0.112 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.885 0.115 0.000
I51.6 Cardiovascular disease, unspecified
0.883 0.117 0.000
M86-M90 Other osteopathies
0.881 0.119 0.000
N13.8 Other obstructive and reflux uropathy
0.879 0.121 0.000
I22 Subsequent myocardial infarction
0.878 0.122 0.000
M06.9 Rheumatoid arthritis, unspecified
0.878 0.122 0.000
J43 Emphysema
0.877 0.123 0.000
I24 Other acute ischaemic heart diseases
0.875 0.125 0.000
C64-C68 Malignant neoplasms of urinary tract
0.873 0.127 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.873 0.127 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.871 0.129 0.000
G30-G32 Other degenerative diseases of the nervous system
0.871 0.129 0.000
M21 Other acquired deformities of limbs
0.871 0.129 0.000
N28 Other disorders of kidney and ureter, not elsewhere classified
0.868 0.132 0.000
Z85.1 Personal history of malignant neoplasm of trachea, bronchus and lung
0.867 0.133 0.000
G93 Other disorders of brain
0.865 0.135 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.865 0.135 0.000
I20 Angina pectoris
0.865 0.135 0.000
C50.2 Upper-inner quadrant of breast
0.864 0.136 0.000
X60-X84 Intentional self-harm
0.863 0.137 0.000
I78.1 Naevus, nonneoplastic
0.861 0.139 0.000
E20-E35 Disorders of other endocrine glands
0.861 0.139 0.000
M80-M85 Disorders of bone density and structure
0.859 0.141 0.000
J40 Bronchitis, not specified as acute or chronic
0.859 0.141 0.000
M54 Dorsalgia
0.858 0.142 0.000
M50.0 Cervical disk disorder with myelopathy
0.857 0.143 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.853 0.147 0.000
B98.0 Helicobacter pylori [H.pylori] as the cause of diseases classified to other chapters
0.853 0.147 0.000
N20 Calculus of kidney and ureter
0.850 0.150 0.000
Z92 Personal history of medical treatment
0.850 0.150 0.000
I35 Nonrheumatic aortic valve disorders
0.849 0.151 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.845 0.155 0.000
G95 Other diseases of spinal cord
0.845 0.155 0.000
J45 Asthma
0.843 0.157 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.835 0.165 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.834 0.166 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.834 0.166 0.000
G20-G26 Extrapyramidal and movement disorders
0.833 0.167 0.000
I11 Hypertensive heart disease
0.831 0.169 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.831 0.169 0.000
M40-M43 Deforming dorsopathies
0.830 0.170 0.000
J43.9 Emphysema, unspecified
0.827 0.173 0.000
C61 Malignant neoplasm of prostate
0.826 0.174 0.000
A00-A09 Intestinal infectious diseases
0.825 0.175 0.000
E70-E90 Metabolic disorders
0.824 0.176 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.823 0.177 0.000
N20.0 Calculus of kidney
0.820 0.180 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.818 0.182 0.000
Z92.1 Personal history of long-term (current) use of anticoagulants
0.816 0.184 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.814 0.186 0.000
M54.2 Cervicalgia
0.813 0.187 0.000
M60-M63 Disorders of muscles
0.811 0.189 0.000
M34 Systemic sclerosis
0.811 0.189 0.000
M35 Other systemic involvement of connective tissue
0.810 0.190 0.000
Z92.3 Personal history of irradiation
0.810 0.190 0.000
J45.9 Asthma, unspecified
0.808 0.192 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.808 0.192 0.000
D05 Carcinoma in situ of breast
0.807 0.193 0.000
V10-V19 Pedal cyclist injured in transport accident
0.806 0.194 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.804 0.196 0.000
H20 Iridocyclitis
0.804 0.196 0.000
M06.4 Inflammatory polyarthropathy
0.803 0.197 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.802 0.198 0.000
J00-J06 Acute upper respiratory infections
0.801 0.199 0.000
E10-E14 Diabetes mellitus
0.801 0.199 0.000
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters
0.798 0.202 0.000
N00-N08 Glomerular diseases
0.798 0.202 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.798 0.202 0.000
I60-I69 Cerebrovascular diseases
0.797 0.203 0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified
0.795 0.205 0.000
I20.0 Unstable angina
0.795 0.205 0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction
0.793 0.207 0.000
D04.3 Skin of other and unspecified parts of face
0.790 0.210 0.000
I21 Acute myocardial infarction
0.790 0.210 0.000
Z85.6 Personal history of leukaemia
0.790 0.210 0.000
C69 Malignant neoplasm of eye and adnexa
0.789 0.211 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.788 0.212 0.000
B35-B49 Mycoses
0.787 0.213 0.000
H43-H45 Disorders of vitreous body and globe
0.787 0.213 0.000
I34.0 Mitral (valve) insufficiency
0.787 0.213 0.000
V40-V49 Car occupant injured in transport accident
0.785 0.215 0.000
D47.1 Chronic myeloproliferative disease
0.785 0.215 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.785 0.215 0.000
N10 Acute tubulo-interstitial nephritis
0.785 0.215 0.000
M51 Other intervertebral disk disorders
0.785 0.215 0.000
E86 Volume depletion
0.784 0.216 0.000
M50.1 Cervical disk disorder with radiculopathy
0.783 0.217 0.000
N18.2 Chronic kidney disease, stage 2
0.783 0.217 0.000
D04.7 Skin of lower limb, including hip
0.782 0.218 0.000
C79 Secondary malignant neoplasm of other sites
0.782 0.218 0.000
Y44 Agents primarily affecting blood constituents
0.781 0.219 0.000
M84 Disorders of continuity of bone
0.781 0.219 0.000
I37 Pulmonary valve disorders
0.780 0.220 0.000
C34.0 Main bronchus
0.779 0.221 0.000
G70-G73 Diseases of myoneural junction and muscle
0.777 0.223 0.000
M21.1 Varus deformity, not elsewhere classified
0.776 0.224 0.000
H18 Other disorders of cornea
0.775 0.225 0.000
I72 Other aneurysm
0.775 0.225 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.771 0.229 0.000
N28.1 Cyst of kidney, acquired
0.771 0.229 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.769 0.231 0.000
D04.6 Skin of upper limb, including shoulder
0.764 0.236 0.000
I47 Paroxysmal tachycardia
0.764 0.236 0.000
Chapter XXII Codes for special purposes
0.764 0.236 0.000
C50.8 Overlapping lesion of breast
0.764 0.236 0.000
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters
0.761 0.239 0.000
G62 Other polyneuropathies
0.760 0.240 0.000
N13.9 Obstructive and reflux uropathy, unspecified
0.760 0.240 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.760 0.240 0.000
D09 Carcinoma in situ of other and unspecified sites
0.758 0.242 0.000
N13.4 Hydroureter
0.758 0.242 0.000
N29 Other disorders of kidney and ureter in diseases classified elsewhere
0.757 0.243 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.755 0.245 0.000
I69 Sequelae of cerebrovascular disease
0.755 0.245 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.754 0.246 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.753 0.247 0.000
G96 Other disorders of central nervous system
0.753 0.247 0.000
D45 Polycythaemia vera
0.752 0.248 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.752 0.248 0.000
E11 Non-insulin-dependent diabetes mellitus
0.752 0.248 0.000
E22 Hyperfunction of pituitary gland
0.752 0.248 0.000
H53-H54 Visual disturbances and blindness
0.751 0.249 0.000
C71 Malignant neoplasm of brain
0.750 0.250 0.000
G30 Alzheimer's disease
0.750 0.250 0.000
L91 Hypertrophic disorders of skin
0.748 0.252 0.000
C97 Malignant neoplasms of independent (primary) multiple sites
0.748 0.252 0.000
M54.29 Cervicalgia-Site unspe
0.748 0.252 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.745 0.255 0.000
E40-E46 Malnutrition
0.744 0.256 0.000
N18.4 Chronic kidney disease, stage 4
0.742 0.258 0.000
D41.4 Bladder
0.742 0.258 0.000
M24 Other specific joint derangements
0.742 0.258 0.000
M35.0 Sicca syndrome [Sjogren]
0.742 0.258 0.000
M15-M19 Arthrosis
0.741 0.259 0.000
I20.9 Angina pectoris, unspecified
0.740 0.260 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.739 0.261 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.737 0.263 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.735 0.265 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.734 0.266 0.000
G40-G47 Episodic and paroxysmal disorders
0.732 0.268 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.730 0.270 0.000
M90 Osteopathies in diseases classified elsewhere
0.728 0.272 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.727 0.273 0.000
B15-B19 Viral hepatitis
0.727 0.273 0.000
M87 Osteonecrosis
0.727 0.273 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.726 0.274 0.000
Y57 Other and unspecified drugs and medicaments
0.724 0.276 0.000
Z92.0 Personal history of contraception
0.723 0.277 0.000
N28.9 Disorder of kidney and ureter, unspecified
0.722 0.278 0.000
N13.6 Pyonephrosis
0.721 0.278 0.000
I73 Other peripheral vascular diseases
0.721 0.279 0.000
B65-B83 Helminthiases
0.721 0.279 0.000
E23 Hypofunction and other disorders of pituitary gland
0.720 0.280 0.000
M50.2 Other cervical disk displacement
0.720 0.280 0.000
Z85.7 Personal history of other malignant neoplasms of lymphoid, haematopoietic and related tissues
0.720 0.280 0.000
I35.8 Other aortic valve disorders
0.719 0.281 0.000
M25 Other joint disorders, not elsewhere classified
0.718 0.282 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.718 0.282 0.000
M43 Other deforming dorsopathies
0.718 0.282 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
0.717 0.283 0.000
I25.6 Silent myocardial ischaemia
0.717 0.283 0.000
I25.4 Coronary artery aneurysm
0.717 0.283 0.000
I23 Certain current complications following acute myocardial infarction
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I33 Acute and subacute endocarditis
0.716 0.283 0.000
M65-M68 Disorders of synovium and tendon
0.716 0.284 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.716 0.284 0.000
M31 Other necrotising vasculopathies
0.716 0.284 0.000
M00-M03 Infectious arthropathies
0.715 0.285 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.715 0.285 0.000
X60 Intentional self-poisoning by and exposure to nonopioid analgesics, antipyretics and antirheumatics
0.715 0.285 0.000
D47.2 Monoclonal gammopathy
0.714 0.286 0.000
I51.4 Myocarditis, unspecified
0.713 0.286 0.000
G90 Disorders of autonomic nervous system
0.712 0.288 0.000
I15 Secondary hypertension
0.712 0.288 0.000
I13 Hypertensive heart and renal disease
0.712 0.288 0.000
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified
0.711 0.288 0.000
L91.8 Other hypertrophic disorders of skin
0.711 0.289 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.711 0.289 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.711 0.289 0.000
G92 Toxic encephalopathy
0.711 0.289 0.000
N11 Chronic tubulo-interstitial nephritis
0.709 0.291 0.000
D06 Carcinoma in situ of cervix uteri
0.709 0.291 0.000
C50.4 Upper-outer quadrant of breast
0.709 0.291 0.000
I27 Other pulmonary heart diseases
0.709 0.291 0.000
I52 Other heart disorders in diseases classified elsewhere
0.708 0.292 0.000
I48 Atrial fibrillation and flutter
0.708 0.292 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.708 0.292 0.000
I41 Myocarditis in diseases classified elsewhere
0.708 0.292 0.000
I40 Acute myocarditis
0.708 0.292 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.708 0.292 0.000
I36 Nonrheumatic tricuspid valve disorders
0.708 0.292 0.000
I32 Pericarditis in diseases classified elsewhere
0.708 0.292 0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.708 0.292 0.000
A04 Other bacterial intestinal infections
0.708 0.292 0.000
C34.2 Middle lobe, bronchus or lung
0.708 0.292 0.000
J46 Status asthmaticus
0.708 0.292 0.000
M21.16 Varus deformity, not elsewhere classified (Lower leg)
0.708 0.292 0.000
G93.1 Anoxic brain damage, not elsewhere classified
0.707 0.293 0.000
I51.5 Myocardial degeneration
0.707 0.293 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.707 0.293 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.707 0.293 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.707 0.293 0.000
I51.0 Cardiac septal defect, acquired
0.707 0.293 0.000
M07 Psoriatic and enteropathic arthropathies
0.706 0.294 0.000
G81 Hemiplegia
0.706 0.294 0.000
W50-W64 Exposure to animate mechanical forces
0.705 0.295 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.704 0.296 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.704 0.296 0.000
C31 Malignant neoplasm of accessory sinuses
0.704 0.296 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.704 0.296 0.000
C37 Malignant neoplasm of thymus
0.704 0.296 0.000
C33 Malignant neoplasm of trachea
0.704 0.296 0.000
J43.2 Centrilobular emphysema
0.704 0.296 0.000
M16 Coxarthrosis [arthrosis of hip]
0.704 0.296 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.704 0.296 0.000
I71 Aortic aneurysm and dissection
0.704 0.296 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.704 0.296 0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy
0.703 0.297 0.000
C45 Mesothelioma
0.702 0.298 0.000
G62.9 Polyneuropathy, unspecified
0.702 0.298 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.702 0.298 0.000
N15 Other renal tubulo-interstitial diseases
0.702 0.298 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.702 0.298 0.000
I34.1 Mitral (valve) prolapse
0.702 0.298 0.000
M53 Other dorsopathies, not elsewhere classified
0.702 0.298 0.000
M91-M94 Chondropathies
0.701 0.299 0.000
I25.3 Aneurysm of heart
0.700 0.300 0.000
I30 Acute pericarditis
0.700 0.300 0.000
H20.0 Acute and subacute iridocyclitis
0.699 0.300 0.000
L20-L30 Dermatitis and eczema
0.699 0.301 0.000
M54.22 Cervicalgia (Cervical region)
0.699 0.301 0.000
N13.7 Vesicoureteral-reflux-associated uropathy
0.699 0.301 0.000
D05.1 Intraductal carcinoma in situ
0.699 0.301 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.699 0.301 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.698 0.301 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.698 0.302 0.000
C34.8 Overlapping lesion of bronchus and lung
0.697 0.302 0.000
B99-B99 Other infectious diseases
0.697 0.303 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.697 0.303 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.697 0.303 0.000
B50-B64 Protozoal diseases
0.697 0.303 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.697 0.303 0.000
A75-A79 Rickettsioses
0.697 0.303 0.000
A70-A74 Other diseases caused by chlamydiae
0.697 0.303 0.000
A65-A69 Other spirochaetal diseases
0.697 0.303 0.000
A20-A28 Certain zoonotic bacterial diseases
0.697 0.303 0.000
A15-A19 Tuberculosis
0.697 0.303 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.697 0.303 0.000
M05 Seropositive rheumatoid arthritis
0.697 0.303 0.000
G99.8 Other specified disorders of nervous system in diseases classified elsewhere
0.697 0.303 0.000
G99.1 Other disorders of autonomic nervous system in other diseases classified elsewhere
0.697 0.303 0.000
G99.0 Autonomic neuropathy in endocrine and metabolic diseases
0.697 0.303 0.000
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters
0.696 0.304 0.000
H20.9 Iridocyclitis, unspecified
0.696 0.304 0.000
Y40 Systemic antibiotics
0.696 0.304 0.000
N20.2 Calculus of kidney with calculus of ureter
0.695 0.305 0.000
M21.3 Wrist or foot drop (acquired)
0.694 0.306 0.000
M10 Gout
0.694 0.306 0.000
C92 Myeloid leukaemia
0.693 0.306 0.000
H43 Disorders of vitreous body
0.693 0.307 0.000
G93.4 Encephalopathy, unspecified
0.693 0.307 0.000
I22.0 Subsequent myocardial infarction of anterior wall
0.692 0.308 0.000
M16.9 Coxarthrosis, unspecified
0.692 0.308 0.000
G95.1 Vascular myelopathies
0.692 0.308 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.692 0.308 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.691 0.309 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.691 0.309 0.000
E74 Other disorders of carbohydrate metabolism
0.691 0.309 0.000
I35.9 Aortic valve disorder, unspecified
0.690 0.310 0.000
E11.9 Without complications
0.690 0.310 0.000
E29 Testicular dysfunction
0.690 0.310 0.000
J95-J99 Other diseases of the respiratory system
0.689 0.311 0.000
E20 Hypoparathyroidism
0.688 0.311 0.000
J44 Other chronic obstructive pulmonary disease
0.687 0.313 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.687 0.313 0.000
C50.6 Axillary tail of breast
0.686 0.314 0.000
Z89 Acquired absence of limb
0.685 0.315 0.000
G83 Other paralytic syndromes
0.685 0.315 0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters
0.685 0.315 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.685 0.315 0.000
Y35-Y36 Legal intervention and operations of war
0.685 0.315 0.000
Y10-Y34 Event of undetermined intent
0.685 0.315 0.000
Y00-Y09 Assault
0.685 0.315 0.000
X85-X99 Assault
0.685 0.315 0.000
X30-X39 Exposure to forces of nature
0.685 0.315 0.000
X10-X19 Contact with heat and hot substances
0.685 0.315 0.000
X00-X09 Exposure to smoke, fire and flames
0.685 0.315 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.685 0.315 0.000
W75-W84 Other accidental threats to breathing
0.685 0.315 0.000
W65-W74 Accidental drowning and submersion
0.685 0.315 0.000
V98-V99 Other and unspecified transport accidents
0.685 0.315 0.000
V95-V97 Air and space transport accidents
0.685 0.315 0.000
V90-V94 Water transport accidents
0.685 0.315 0.000
V70-V79 Bus occupant injured in transport accident
0.685 0.315 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.685 0.315 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.685 0.315 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.685 0.315 0.000
V01-V09 Pedestrian injured in transport accident
0.685 0.315 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.685 0.315 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.683 0.317 0.000
L81 Other disorders of pigmentation
0.683 0.317 0.000
A80-A89 Viral infections of the central nervous system
0.683 0.317 0.000
I11.0 Hypertensive heart disease with (congestive) heart failure
0.683 0.317 0.000
N13.3 Other and unspecified hydronephrosis
0.682 0.318 0.000
M45-M49 Spondylopathies
0.681 0.319 0.000
Y54.3 Benzothiadiazine derivatives
0.681 0.319 0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot
0.680 0.320 0.000
X50-X57 Overexertion, travel and privation
0.679 0.320 0.000
I35.1 Aortic (valve) insufficiency
0.679 0.321 0.000
G95.9 Disease of spinal cord, unspecified
0.679 0.321 0.000
M34.9 Systemic sclerosis, unspecified
0.678 0.322 0.000
N28.8 Other specified disorders of kidney and ureter
0.677 0.322 0.000
C50.0 Nipple and areola
0.677 0.323 0.000
Z51 Other medical care
0.677 0.323 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.677 0.323 0.000
D02 Carcinoma in situ of middle ear and respiratory system
0.677 0.323 0.000
D01 Carcinoma in situ of other and unspecified digestive organs
0.677 0.323 0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.677 0.323 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.677 0.323 0.000
M14 Arthropathies in other diseases classified elsewhere
0.676 0.324 0.000
M12 Other specific arthropathies
0.676 0.324 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.676 0.324 0.000
M08 Juvenile arthritis
0.676 0.324 0.000
M62 Other disorders of muscle
0.676 0.324 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.675 0.325 0.000
V18 Pedal cyclist injured in noncollision transport accident
0.675 0.325 0.000
Y44.2 Anticoagulants
0.674 0.325 0.000
Z81 Family history of mental and behavioural disorders
0.673 0.327 0.000
X68 Intentional self-poisoning by and exposure to pesticides
0.672 0.328 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.672 0.328 0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.671 0.329 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.671 0.329 0.000
M54.1 Radiculopathy
0.671 0.329 0.000
M80 Osteoporosis with pathological fracture
0.671 0.329 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.670 0.330 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.670 0.330 0.000
Y52 Agents primarily affecting the cardiovascular system
0.670 0.330 0.000
X20-X29 Contact with venomous animals and plants
0.668 0.332 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.668 0.332 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.668 0.332 0.000
M33 Dermatopolymyositis
0.668 0.332 0.000
M32 Systemic lupus erythematosus
0.668 0.332 0.000
M30 Polyarteritis nodosa and related conditions
0.668 0.332 0.000
N27 Small kidney of unknown cause
0.667 0.332 0.000
N25 Disorders resulting from impaired renal tubular function
0.667 0.332 0.000
I47.0 Reentry ventricular arrhythmia
0.667 0.333 0.000
N18.8 Other chronic renal failure
0.667 0.333 0.000
N18.1 Chronic kidney disease, stage 1
0.667 0.333 0.000
M21.6 Other acquired deformities of ankle and foot
0.667 0.333 0.000
M50.9 Cervical disk disorder, unspecified
0.667 0.333 0.000
M50.8 Other cervical disk disorders
0.667 0.333 0.000
Y59 Other and unspecified vaccines and biological substances
0.667 0.333 0.000
Y58 Bacterial vaccines
0.667 0.333 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.667 0.333 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.667 0.333 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.667 0.333 0.000
Y48 Anaesthetics and therapeutic gases
0.667 0.333 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.667 0.333 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.667 0.333 0.000
G93.9 Disorder of brain, unspecified
0.666 0.334 0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.666 0.334 0.000
N26 Unspecified contracted kidney
0.666 0.334 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.666 0.334 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.665 0.335 0.000
N02 Recurrent and persistent haematuria
0.665 0.335 0.000
N99-N99 Other disorders of the genitourinary system
0.665 0.335 0.000
J41 Simple and mucopurulent chronic bronchitis
0.664 0.335 0.000
V49 Car occupant injured in other and unspecified transport accidents
0.663 0.336 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.663 0.337 0.000
M34.8 Other forms of systemic sclerosis
0.662 0.338 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.662 0.338 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.662 0.338 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.662 0.338 0.000
Z51.1 Chemotherapy session for neoplasm
0.662 0.338 0.000
I70 Atherosclerosis
0.661 0.339 0.000
M24.0 Loose body in joint
0.660 0.340 0.000
G93.3 Postviral fatigue syndrome
0.659 0.341 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.659 0.341 0.000
D47.3 Essential (haemorrhagic) thrombocythaemia
0.658 0.342 0.000
G25 Other extrapyramidal and movement disorders
0.658 0.342 0.000
C69.3 Choroid
0.658 0.342 0.000
V80-V89 Other land transport accidents
0.656 0.344 0.000
M06.8 Other specified rheumatoid arthritis
0.656 0.344 0.000
M06.3 Rheumatoid nodule
0.656 0.344 0.000
M06.2 Rheumatoid bursitis
0.656 0.344 0.000
M06.1 Adult-onset Still's disease
0.656 0.344 0.000
E50-E64 Other nutritional deficiencies
0.655 0.345 0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.655 0.345 0.000
B37 Candidiasis
0.655 0.345 0.000
H17 Corneal scars and opacities
0.654 0.345 0.000
C15-C26 Malignant neoplasms of digestive organs
0.654 0.346 0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.654 0.346 0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.653 0.347 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.653 0.347 0.000
M70-M79 Other soft tissue disorders
0.653 0.347 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.653 0.347 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.652 0.348 0.000
I50 Heart failure
0.652 0.348 0.000
C91 Lymphoid leukaemia
0.652 0.348 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.650 0.350 0.000
C69.9 Eye, unspecified
0.649 0.351 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.649 0.351 0.000
H50 Other strabismus
0.649 0.351 0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.649 0.351 0.000
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system
0.648 0.352 0.000
C70 Malignant neoplasm of meninges
0.648 0.352 0.000
I11.9 Hypertensive heart disease without (congestive) heart failure
0.648 0.352 0.000
D04.9 Skin, unspecified
0.648 0.352 0.000
D04.8 Skin of other sites
0.648 0.352 0.000
D04.4 Skin of scalp and neck
0.648 0.352 0.000
D04.2 Skin of ear and external auricular canal
0.648 0.352 0.000
D04.1 Skin of eyelid, including canthus
0.648 0.352 0.000
D04.0 Skin of lip
0.648 0.352 0.000
H16 Keratitis
0.647 0.353 0.000
H18.4 Corneal degeneration
0.647 0.353 0.000
D04.5 Skin of trunk
0.646 0.353 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.646 0.354 0.000
C67 Malignant neoplasm of bladder
0.646 0.354 0.000
J06 Acute upper respiratory infections of multiple and unspecified sites
0.646 0.354 0.000
M88 Paget's disease of bone [osteitis deformans]
0.645 0.355 0.000
Y45.2 Propionic acid derivatives
0.644 0.356 0.000
I22.1 Subsequent myocardial infarction of inferior wall
0.644 0.356 0.000
D43.2 Brain, unspecified
0.643 0.357 0.000
C63 Malignant neoplasm of other and unspecified male genital organs
0.643 0.357 0.000
C60 Malignant neoplasm of penis
0.643 0.357 0.000
M43.1 Spondylolisthesis
0.643 0.357 0.000
M86 Osteomyelitis
0.642 0.358 0.000
M50.3 Other cervical disk degeneration
0.641 0.359 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.641 0.359 0.000
B98.1 Vibrio vulnificus as the cause of diseases classified to other chapters
0.641 0.359 0.000
Z85.0 Personal history of malignant neoplasm of digestive organs
0.641 0.359 0.000
Z85.9 Personal history of malignant neoplasm, unspecified
0.641 0.359 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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