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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs115670257
log Bayes Factor = 13.9956
Chromosome 1   position 152,184,907  (GRCh37) Explore rs115670257 on Ensembl!
Variant rs115670257 is part of Cluster X0050

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.999 0.001 0.000
C15-C26 Malignant neoplasms of digestive organs
0.999 0.001 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.999 0.001 0.000
C18 Malignant neoplasm of colon
0.998 0.002 0.000
Chapter X Diseases of the respiratory system
0.995 0.005 0.000
Chapter IX Diseases of the circulatory system
0.993 0.007 0.000
J95-J99 Other diseases of the respiratory system
0.992 0.008 0.000
Chapter XX External causes of morbidity and mortality
0.992 0.008 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.990 0.010 0.000
J98 Other respiratory disorders
0.990 0.010 0.000
Z51 Other medical care
0.990 0.010 0.000
Chapter XXI Factors influencing health status and contact with health services
0.989 0.011 0.000
Z51.1 Chemotherapy session for neoplasm
0.989 0.011 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.989 0.011 0.000
C79 Secondary malignant neoplasm of other sites
0.989 0.011 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.988 0.012 0.000
J98.1 Pulmonary collapse
0.982 0.018 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.982 0.018 0.000
C18.7 Sigmoid colon
0.979 0.021 0.000
I30-I52 Other forms of heart disease
0.979 0.021 0.000
C78.2 Secondary malignant neoplasm of pleura
0.974 0.026 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.967 0.033 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.966 0.034 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.965 0.035 0.000
C50-C50 Malignant neoplasm of breast
0.961 0.039 0.000
J09-J18 Influenza and pneumonia
0.951 0.049 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.944 0.056 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.944 0.056 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.944 0.056 0.000
Y43 Primarily systemic agents
0.941 0.059 0.000
C51-C58 Malignant neoplasms of female genital organs
0.941 0.059 0.000
D70 Agranulocytosis
0.936 0.064 0.000
C50 Malignant neoplasm of breast
0.933 0.067 0.000
I44 Atrioventricular and left bundle-branch block
0.929 0.071 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.925 0.075 0.000
Z51.5 Palliative care
0.924 0.076 0.000
Y43.3 Other antineoplastic drugs
0.923 0.077 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.921 0.079 0.000
C78.7 Secondary malignant neoplasm of liver
0.916 0.084 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.914 0.086 0.000
Z85 Personal history of malignant neoplasm
0.914 0.086 0.000
S60-S69 Injuries to the wrist and hand
0.905 0.095 0.000
Z85.4 Personal history of malignant neoplasm of genital organs
0.904 0.096 0.000
Y85 Sequelae of transport accidents
0.903 0.097 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.903 0.097 0.000
I20-I25 Ischaemic heart diseases
0.903 0.097 0.000
C50.4 Upper-outer quadrant of breast
0.903 0.097 0.000
Z45 Adjustment and management of implanted device
0.902 0.098 0.000
C18.2 Ascending colon
0.898 0.102 0.000
I42 Cardiomyopathy
0.897 0.103 0.000
C77.3 Axillary and upper limb lymph nodes
0.892 0.108 0.000
Z85.8 Personal history of malignant neoplasms of other organs and systems
0.890 0.110 0.000
S90-S99 Injuries to the ankle and foot
0.888 0.112 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.887 0.113 0.000
J98.4 Other disorders of lung
0.886 0.114 0.000
Z85.3 Personal history of malignant neoplasm of breast
0.884 0.116 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.880 0.120 0.000
I10-I15 Hypertensive diseases
0.878 0.122 0.000
C56 Malignant neoplasm of ovary
0.873 0.127 0.000
C77.9 Lymph node, unspecified
0.870 0.130 0.000
I46 Cardiac arrest
0.870 0.130 0.000
Z92 Personal history of medical treatment
0.868 0.132 0.000
C77.1 Intrathoracic lymph nodes
0.867 0.133 0.000
Z51.3 Blood transfusion without reported diagnosis
0.865 0.135 0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified
0.864 0.136 0.000
C34 Malignant neoplasm of bronchus and lung
0.864 0.136 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.864 0.136 0.000
Chapter VIII Diseases of the ear and mastoid process
0.863 0.137 0.000
J18 Pneumonia, organism unspecified
0.863 0.137 0.000
Y85.0 Sequelae of motor-vehicle accident
0.861 0.139 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.854 0.145 0.000
Z92.3 Personal history of irradiation
0.853 0.147 0.000
C77.2 Intra-abdominal lymph nodes
0.848 0.152 0.000
Z92.6 Personal history of chemotherapy for neoplastic disease
0.848 0.152 0.000
I34 Nonrheumatic mitral valve disorders
0.847 0.153 0.000
Z45.0 Adjustment and management of cardiac pacemaker
0.843 0.157 0.000
S40-S49 Injuries to the shoulder and upper arm
0.843 0.157 0.000
C16 Malignant neoplasm of stomach
0.842 0.158 0.000
Chapter VI Diseases of the nervous system
0.841 0.159 0.000
C18.9 Colon, unspecified
0.841 0.159 0.000
I21 Acute myocardial infarction
0.840 0.160 0.000
I44.2 Atrioventricular block, complete
0.839 0.161 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.838 0.162 0.000
I22 Subsequent myocardial infarction
0.836 0.164 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.834 0.166 0.000
I27 Other pulmonary heart diseases
0.832 0.168 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.830 0.170 0.000
C21 Malignant neoplasm of anus and anal canal
0.830 0.170 0.000
V10-V19 Pedal cyclist injured in transport accident
0.828 0.172 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.828 0.172 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.827 0.173 0.000
D73 Diseases of spleen
0.827 0.173 0.000
I12 Hypertensive renal disease
0.826 0.174 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.824 0.176 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.822 0.178 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.819 0.181 0.000
I50 Heart failure
0.817 0.183 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.816 0.184 0.000
C34.9 Bronchus or lung, unspecified
0.810 0.190 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.810 0.190 0.000
J98.8 Other specified respiratory disorders
0.809 0.191 0.000
Z48 Other surgical follow-up care
0.809 0.191 0.000
S60 Superficial injury of wrist and hand
0.807 0.193 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.807 0.193 0.000
C53 Malignant neoplasm of cervix uteri
0.806 0.193 0.000
I44.0 Atrioventricular block, first degree
0.806 0.194 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.806 0.194 0.000
J18.9 Pneumonia, unspecified
0.806 0.194 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.806 0.194 0.000
H65-H75 Diseases of middle ear and mastoid
0.802 0.198 0.000
C18.3 Hepatic flexure
0.801 0.199 0.000
Z42 Follow-up care involving plastic surgery
0.799 0.201 0.000
I46.0 Cardiac arrest with successful resuscitation
0.799 0.201 0.000
I21.9 Acute myocardial infarction, unspecified
0.799 0.201 0.000
I50.1 Left ventricular failure
0.798 0.202 0.000
W00-W19 Falls
0.793 0.207 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.792 0.208 0.000
S80-S89 Injuries to the knee and lower leg
0.792 0.208 0.000
C18.4 Transverse colon
0.789 0.211 0.000
Z85.1 Personal history of malignant neoplasm of trachea, bronchus and lung
0.788 0.212 0.000
C18.6 Descending colon
0.787 0.213 0.000
S50-S59 Injuries to the elbow and forearm
0.785 0.215 0.000
Y88 Sequelae of surgical and medical care as external cause
0.785 0.215 0.000
S10-S19 Injuries to the neck
0.784 0.216 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.783 0.217 0.000
I12.0 Hypertensive renal disease with renal failure
0.780 0.220 0.000
Q60-Q64 Congenital malformations of the urinary system
0.780 0.220 0.000
C18.1 Appendix
0.779 0.221 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.778 0.222 0.000
D80-D89 Certain disorders involving the immune mechanism
0.777 0.223 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.776 0.224 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.774 0.226 0.000
J90-J94 Other diseases of pleura
0.774 0.226 0.000
J20-J22 Other acute lower respiratory infections
0.773 0.227 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.773 0.227 0.000
L60-L75 Disorders of skin appendages
0.772 0.228 0.000
C50.9 Breast, unspecified
0.768 0.232 0.000
V40-V49 Car occupant injured in transport accident
0.767 0.233 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.764 0.236 0.000
S70-S79 Injuries to the hip and thigh
0.764 0.236 0.000
Z51.0 Radiotherapy session
0.763 0.237 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.763 0.237 0.000
D60-D64 Aplastic and other anaemias
0.763 0.237 0.000
I34.1 Mitral (valve) prolapse
0.761 0.239 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.760 0.240 0.000
T83.0 Mechanical complication of urinary (indwelling) catheter
0.757 0.243 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.757 0.243 0.000
C77.8 Lymph nodes of multiple regions
0.755 0.244 0.000
C78.0 Secondary malignant neoplasm of lung
0.754 0.246 0.000
I42.0 Dilated cardiomyopathy
0.751 0.249 0.000
C18.5 Splenic flexure
0.751 0.249 0.000
S92 Fracture of foot, except ankle
0.751 0.249 0.000
Z43 Attention to artificial openings
0.750 0.250 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.750 0.250 0.000
D75 Other diseases of blood and blood-forming organs
0.750 0.250 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.746 0.254 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.746 0.254 0.000
J10 Influenza due to identified influenza virus
0.744 0.255 0.000
T86 Failure and rejection of transplanted organs and tissues
0.743 0.257 0.000
I36 Nonrheumatic tricuspid valve disorders
0.742 0.258 0.000
S61 Open wound of wrist and hand
0.742 0.258 0.000
Y44 Agents primarily affecting blood constituents
0.740 0.260 0.000
Z44 Fitting and adjustment of external prosthetic device
0.739 0.261 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.739 0.261 0.000
I30 Acute pericarditis
0.738 0.262 0.000
C79.6 Secondary malignant neoplasm of ovary
0.736 0.264 0.000
D68 Other coagulation defects
0.736 0.264 0.000
V80-V89 Other land transport accidents
0.734 0.266 0.000
S00-S09 Injuries to the head
0.732 0.268 0.000
C77.4 Inguinal and lower limb lymph nodes
0.731 0.269 0.000
X50-X57 Overexertion, travel and privation
0.730 0.269 0.000
Z94 Transplanted organ and tissue status
0.730 0.270 0.000
I49 Other cardiac arrhythmias
0.730 0.270 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.730 0.270 0.000
T79-T79 Certain early complications of trauma
0.730 0.270 0.000
Q50-Q56 Congenital malformations of genital organs
0.729 0.271 0.000
T85.4 Mechanical complication of breast prosthesis and implant
0.728 0.272 0.000
D00-D09 In situ neoplasms
0.728 0.272 0.000
Z90.1 Acquired absence of breast(s)
0.728 0.272 0.000
C51 Malignant neoplasm of vulva
0.727 0.273 0.000
C50.2 Upper-inner quadrant of breast
0.727 0.273 0.000
Z54 Convalescence
0.726 0.274 0.000
Y85.9 Sequelae of other and unspecified transport accidents
0.726 0.274 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.726 0.274 0.000
Z49 Care involving dialysis
0.725 0.275 0.000
Z51.8 Other specified medical care
0.725 0.275 0.000
I42.6 Alcoholic cardiomyopathy
0.725 0.275 0.000
I27.0 Primary pulmonary hypertension
0.725 0.275 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.724 0.276 0.000
T87 Complications peculiar to reattachment and amputation
0.723 0.277 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.719 0.281 0.000
I15 Secondary hypertension
0.719 0.281 0.000
T90 Sequelae of injuries of head
0.719 0.281 0.000
I22.1 Subsequent myocardial infarction of inferior wall
0.719 0.281 0.000
I42.1 Obstructive hypertrophic cardiomyopathy
0.718 0.282 0.000
J60-J70 Lung diseases due to external agents
0.718 0.282 0.000
Q80-Q89 Other congenital malformations
0.718 0.282 0.000
S62 Fracture at wrist and hand level
0.717 0.282 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.717 0.283 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.716 0.283 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.716 0.283 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.716 0.284 0.000
C17 Malignant neoplasm of small intestine
0.716 0.284 0.000
C23 Malignant neoplasm of gallbladder
0.716 0.284 0.000
T33-T35 Frostbite
0.716 0.284 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.716 0.284 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.716 0.284 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.716 0.284 0.000
T00-T07 Injuries involving multiple body regions
0.716 0.284 0.000
Z45.8 Adjustment and management of other implanted devices
0.716 0.284 0.000
C18.8 Overlapping lesion of colon
0.715 0.284 0.000
S42 Fracture of shoulder and upper arm
0.715 0.285 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.715 0.285 0.000
Y40 Systemic antibiotics
0.715 0.285 0.000
C16.5 Lesser curvature of stomach, unspecified
0.713 0.287 0.000
C18.0 Caecum
0.712 0.288 0.000
C77.5 Intrapelvic lymph nodes
0.712 0.288 0.000
I00-I02 Acute rheumatic fever
0.712 0.288 0.000
C77.0 Lymph nodes of head, face and neck
0.712 0.288 0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts
0.712 0.288 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.711 0.288 0.000
J96 Respiratory failure, not elsewhere classified
0.711 0.288 0.000
V18 Pedal cyclist injured in noncollision transport accident
0.711 0.289 0.000
Y35-Y36 Legal intervention and operations of war
0.711 0.289 0.000
Y10-Y34 Event of undetermined intent
0.711 0.289 0.000
Y00-Y09 Assault
0.711 0.289 0.000
X85-X99 Assault
0.711 0.289 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.711 0.289 0.000
X30-X39 Exposure to forces of nature
0.711 0.289 0.000
X20-X29 Contact with venomous animals and plants
0.711 0.289 0.000
X10-X19 Contact with heat and hot substances
0.711 0.289 0.000
X00-X09 Exposure to smoke, fire and flames
0.711 0.289 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.711 0.289 0.000
W75-W84 Other accidental threats to breathing
0.711 0.289 0.000
W65-W74 Accidental drowning and submersion
0.711 0.289 0.000
W50-W64 Exposure to animate mechanical forces
0.711 0.289 0.000
V98-V99 Other and unspecified transport accidents
0.711 0.289 0.000
V95-V97 Air and space transport accidents
0.711 0.289 0.000
V90-V94 Water transport accidents
0.711 0.289 0.000
V70-V79 Bus occupant injured in transport accident
0.711 0.289 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.711 0.289 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.711 0.289 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.711 0.289 0.000
V01-V09 Pedestrian injured in transport accident
0.711 0.289 0.000
C53.9 Cervix uteri, unspecified
0.710 0.290 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.710 0.290 0.000
J98.9 Respiratory disorder, unspecified
0.710 0.290 0.000
J98.6 Disorders of diaphragm
0.710 0.290 0.000
J98.5 Diseases of mediastinum, not elsewhere classified
0.710 0.290 0.000
J98.3 Compensatory emphysema
0.710 0.290 0.000
J98.2 Interstitial emphysema
0.710 0.290 0.000
Z51.9 Medical care, unspecified
0.709 0.290 0.000
Z51.6 Desensitisation to allergens
0.709 0.290 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.709 0.291 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.709 0.291 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.709 0.291 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.709 0.291 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.708 0.292 0.000
H73 Other disorders of tympanic membrane
0.708 0.292 0.000
C50.1 Central portion of breast
0.708 0.292 0.000
J98.0 Diseases of bronchus, not elsewhere classified
0.708 0.292 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.707 0.292 0.000
S90 Superficial injury of ankle and foot
0.707 0.293 0.000
C50.0 Nipple and areola
0.706 0.293 0.000
D55-D59 Haemolytic anaemias
0.704 0.296 0.000
Z40 Prophylactic surgery
0.704 0.296 0.000
C79.2 Secondary malignant neoplasm of skin
0.703 0.297 0.000
I44.7 Left bundle-branch block, unspecified
0.703 0.297 0.000
T91 Sequelae of injuries of neck and trunk
0.703 0.297 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.702 0.298 0.000
I52 Other heart disorders in diseases classified elsewhere
0.702 0.298 0.000
I48 Atrial fibrillation and flutter
0.702 0.298 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.702 0.298 0.000
I41 Myocarditis in diseases classified elsewhere
0.702 0.298 0.000
I40 Acute myocarditis
0.702 0.298 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.702 0.298 0.000
I37 Pulmonary valve disorders
0.702 0.298 0.000
I32 Pericarditis in diseases classified elsewhere
0.702 0.298 0.000
I24 Other acute ischaemic heart diseases
0.700 0.300 0.000
I27.9 Pulmonary heart disease, unspecified
0.698 0.302 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.697 0.303 0.000
T80.2 Infections following infusion, transfusion and therapeutic injection
0.695 0.305 0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts
0.695 0.305 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.695 0.305 0.000
Y59 Other and unspecified vaccines and biological substances
0.694 0.306 0.000
Y58 Bacterial vaccines
0.694 0.306 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.694 0.306 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.694 0.306 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.694 0.306 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.694 0.306 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.694 0.306 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.694 0.306 0.000
Y48 Anaesthetics and therapeutic gases
0.694 0.306 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.694 0.306 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.694 0.306 0.000
I44.3 Other and unspecified atrioventricular block
0.693 0.306 0.000
T85.9 Unspecified complication of internal prosthetic device, implant and graft
0.693 0.307 0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts
0.693 0.307 0.000
T85.2 Mechanical complication of intraocular lens
0.693 0.307 0.000
T85.1 Mechanical complication of implanted electronic stimulator of nervous system
0.693 0.307 0.000
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt
0.693 0.307 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.692 0.308 0.000
D74 Methaemoglobinaemia
0.692 0.308 0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.692 0.308 0.000
D71 Functional disorders of polymorphonuclear neutrophils
0.692 0.308 0.000
S41 Open wound of shoulder and upper arm
0.692 0.308 0.000
T88.6 Anaphylactic shock due to adverse effect of correct drug or medicament properly administered
0.690 0.310 0.000
C16.9 Stomach, unspecified
0.689 0.311 0.000
Z48.9 Surgical follow-up care, unspecified
0.688 0.312 0.000
S64 Injury of nerves at wrist and hand level
0.688 0.312 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.685 0.314 0.000
C21.0 Anus, unspecified
0.685 0.315 0.000
Z51.4 Preparatory care for treatment, not elsewhere classified
0.685 0.315 0.000
V20-V29 Motorcycle rider injured in transport accident
0.684 0.316 0.000
T88.7 Unspecified adverse effect of drug or medicament
0.684 0.316 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.684 0.316 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.683 0.316 0.000
Chapter XXII Codes for special purposes
0.683 0.317 0.000
I11 Hypertensive heart disease
0.683 0.317 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.682 0.318 0.000
J91 Pleural effusion in conditions classified elsewhere
0.682 0.318 0.000
J17 Pneumonia in diseases classified elsewhere
0.682 0.318 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.682 0.318 0.000
J12 Viral pneumonia, not elsewhere classified
0.682 0.318 0.000
J11 Influenza, virus not identified
0.682 0.318 0.000
J14 Pneumonia due to Haemophilus influenzae
0.682 0.318 0.000
J09 Influenza due to certain identified influenza virus
0.682 0.318 0.000
S61.1 Open wound of finger(s) with damage to nail
0.681 0.319 0.000
J00-J06 Acute upper respiratory infections
0.680 0.320 0.000
Z81 Family history of mental and behavioural disorders
0.679 0.320 0.000
D72 Other disorders of white blood cells
0.678 0.322 0.000
I27.2 Other secondary pulmonary hypertension
0.678 0.322 0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards
0.678 0.322 0.000
G35 Multiple sclerosis
0.677 0.323 0.000
Y89 Sequelae of other external causes
0.677 0.323 0.000
Y87 Sequelae of intentional self-harm, assault and events of undetermined intent
0.677 0.323 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.677 0.323 0.000
D73.5 Infarction of spleen
0.676 0.324 0.000
I42.9 Cardiomyopathy, unspecified
0.676 0.324 0.000
Y43.9 Primarily systemic agent, unspecified
0.675 0.325 0.000
Y43.8 Other primarily systemic agents, not elsewhere classified
0.675 0.325 0.000
Y43.6 Enzymes, not elsewhere classified
0.675 0.325 0.000
Y43.5 Acidifying and alkalising agents
0.675 0.325 0.000
Y43.4 Immunosuppressive agents
0.675 0.325 0.000
Y43.2 Antineoplastic natural products
0.675 0.325 0.000
Y43.1 Antineoplastic antimetabolites
0.675 0.325 0.000
Y43.0 Antiallergic and antiemetic drugs
0.675 0.325 0.000
H60-H62 Diseases of external ear
0.675 0.325 0.000
C57 Malignant neoplasm of other and unspecified female genital organs
0.675 0.325 0.000
C58 Malignant neoplasm of placenta
0.675 0.325 0.000
C55 Malignant neoplasm of uterus, part unspecified
0.675 0.325 0.000
C52 Malignant neoplasm of vagina
0.675 0.325 0.000
G20-G26 Extrapyramidal and movement disorders
0.674 0.326 0.000
C71 Malignant neoplasm of brain
0.674 0.326 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.674 0.326 0.000
T88.8 Other specified complications of surgical and medical care, not elsewhere classified
0.673 0.326 0.000
D73.0 Hyposplenism
0.673 0.327 0.000
L65 Other nonscarring hair loss
0.673 0.327 0.000
I45 Other conduction disorders
0.673 0.327 0.000
S20-S29 Injuries to the thorax
0.672 0.328 0.000
I22.8 Subsequent myocardial infarction of other sites
0.672 0.328 0.000
Y88.3 Sequelae of surgical and medical procedures as the cause of abnormal reaction of the patient or of later complication, without mention of misadventure at the time of the procedure
0.670 0.329 0.000
C50.6 Axillary tail of breast
0.669 0.331 0.000
Z45.2 Adjustment and management of vascular access device
0.668 0.332 0.000
C73 Malignant neoplasm of thyroid gland
0.667 0.333 0.000
Z41 Procedures for purposes other than remedying health state
0.667 0.333 0.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system
0.666 0.334 0.000
I44.6 Other and unspecified fascicular block
0.666 0.334 0.000
I44.5 Left posterior fascicular block
0.666 0.334 0.000
I44.4 Left anterior fascicular block
0.666 0.334 0.000
G90-G99 Other disorders of the nervous system
0.665 0.335 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.663 0.337 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.663 0.337 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.663 0.337 0.000
Q35-Q37 Cleft lip and cleft palate
0.663 0.337 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.663 0.337 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.663 0.337 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.663 0.337 0.000
Z82.3 Family history of stroke
0.663 0.337 0.000
Y52 Agents primarily affecting the cardiovascular system
0.661 0.338 0.000
Q00-Q07 Congenital malformations of the nervous system
0.660 0.340 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.660 0.340 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.660 0.340 0.000
C32 Malignant neoplasm of larynx
0.660 0.340 0.000
C31 Malignant neoplasm of accessory sinuses
0.660 0.340 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.660 0.340 0.000
C37 Malignant neoplasm of thymus
0.660 0.340 0.000
C33 Malignant neoplasm of trachea
0.660 0.340 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.660 0.340 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.660 0.340 0.000
C83.3 Large cell (diffuse)
0.659 0.341 0.000
L50-L54 Urticaria and erythema
0.658 0.341 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.658 0.342 0.000
X60-X84 Intentional self-harm
0.657 0.343 0.000
C34.1 Upper lobe, bronchus or lung
0.657 0.343 0.000
S60.9 Superficial injury of wrist and hand, unspecified
0.657 0.343 0.000
Y45.2 Propionic acid derivatives
0.656 0.344 0.000
Z85.0 Personal history of malignant neoplasm of digestive organs
0.655 0.345 0.000
Z85.9 Personal history of malignant neoplasm, unspecified
0.655 0.345 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.655 0.345 0.000
Z85.7 Personal history of other malignant neoplasms of lymphoid, haematopoietic and related tissues
0.654 0.346 0.000
I33 Acute and subacute endocarditis
0.654 0.346 0.000
S67 Crushing injury of wrist and hand
0.654 0.346 0.000
C25 Malignant neoplasm of pancreas
0.653 0.347 0.000
S60.8 Other superficial injuries of wrist and hand
0.653 0.347 0.000
I21.4 Acute subendocardial myocardial infarction
0.653 0.347 0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system
0.651 0.349 0.000
S60.2 Contusion of other parts of wrist and hand
0.651 0.349 0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified
0.650 0.349 0.000
S81 Open wound of lower leg
0.650 0.350 0.000
I42.2 Other hypertrophic cardiomyopathy
0.649 0.351 0.000
J18.1 Lobar pneumonia, unspecified
0.649 0.351 0.000
S65 Injury of blood vessels at wrist and hand level
0.649 0.351 0.000
C50.5 Lower-outer quadrant of breast
0.649 0.351 0.000
S99 Other and unspecified injuries of ankle and foot
0.649 0.351 0.000
C50.8 Overlapping lesion of breast
0.648 0.352 0.000
C34.3 Lower lobe, bronchus or lung
0.648 0.352 0.000
Z84 Family history of other conditions
0.647 0.353 0.000
I23 Certain current complications following acute myocardial infarction
0.647 0.353 0.000
Z45.9 Adjustment and management of unspecified implanted device
0.647 0.353 0.000
Z45.3 Adjustment and management of implanted hearing device
0.647 0.353 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.643 0.357 0.000
I42.8 Other cardiomyopathies
0.643 0.357 0.000
I42.7 Cardiomyopathy due to drugs and other external agents
0.643 0.357 0.000
I42.5 Other restrictive cardiomyopathy
0.643 0.357 0.000
I42.4 Endocardial fibroelastosis
0.643 0.357 0.000
I42.3 Endomyocardial (eosinophilic) disease
0.643 0.357 0.000
Z42.1 Follow-up care involving plastic surgery of breast
0.642 0.358 0.000
L71 Rosacea
0.642 0.358 0.000
H73.8 Other specified disorders of tympanic membrane
0.641 0.359 0.000
Z43.1 Attention to gastrostomy
0.641 0.359 0.000
Q61 Cystic kidney disease
0.641 0.359 0.000
T92 Sequelae of injuries of upper limb
0.641 0.359 0.000
C69 Malignant neoplasm of eye and adnexa
0.640 0.360 0.000
H74 Other disorders of middle ear and mastoid
0.640 0.360 0.000
D86 Sarcoidosis
0.638 0.362 0.000
I12.9 Hypertensive renal disease without renal failure
0.637 0.363 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.637 0.363 0.000
Y45.1 Salicylates
0.637 0.363 0.000
S98 Traumatic amputation of ankle and foot
0.637 0.363 0.000
S97 Crushing injury of ankle and foot
0.637 0.363 0.000
S96 Injury of muscle and tendon at ankle and foot level
0.637 0.363 0.000
S95 Injury of blood vessels at ankle and foot level
0.637 0.363 0.000
S94 Injury of nerves at ankle and foot level
0.637 0.363 0.000
S91 Open wound of ankle and foot
0.637 0.363 0.000
Z42.3 Follow-up care involving plastic surgery of upper extremity
0.636 0.364 0.000
D68.2 Hereditary deficiency of other clotting factors
0.636 0.364 0.000
Z52 Donors of organs and tissues
0.636 0.364 0.000
I28 Other diseases of pulmonary vessels
0.636 0.364 0.000
Z48.8 Other specified surgical follow-up care
0.636 0.364 0.000
Chapter XIV Diseases of the genitourinary system
0.635 0.365 0.000
C81 Hodgkin's disease
0.635 0.365 0.000
I49.9 Cardiac arrhythmia, unspecified
0.634 0.366 0.000
I44.1 Atrioventricular block, second degree
0.634 0.366 0.000
G70-G73 Diseases of myoneural junction and muscle
0.633 0.367 0.000
C21.1 Anal canal
0.632 0.368 0.000
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract
0.631 0.369 0.000
S12 Fracture of neck
0.630 0.370 0.000
I13 Hypertensive heart and renal disease
0.630 0.370 0.000
L70 Acne
0.628 0.372 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.626 0.373 0.000
S86 Injury of muscle and tendon at lower leg level
0.626 0.374 0.000
W10 Fall on and from stairs and steps
0.626 0.374 0.000
I46.1 Sudden cardiac death, so described
0.624 0.376 0.000
Z82.0 Family history of epilepsy and other diseases of the nervous system
0.624 0.376 0.000
J22 Unspecified acute lower respiratory infection
0.623 0.377 0.000
G37 Other demyelinating diseases of central nervous system
0.623 0.377 0.000
T80.8 Other complications following infusion, transfusion and therapeutic injection
0.623 0.377 0.000
Z92.9 Personal history of medical treatment, unspecified
0.622 0.378 0.000
Z92.8 Personal history of other medical treatment
0.622 0.378 0.000
Z92.5 Personal history of rehabilitation measures
0.622 0.378 0.000
W18 Other fall on same level
0.622 0.378 0.000
S92.0 Fracture of calcaneus
0.621 0.379 0.000
J95.8 Other postprocedural respiratory disorders
0.621 0.379 0.000
T18 Foreign body in alimentary tract
0.620 0.380 0.000
C34.8 Overlapping lesion of bronchus and lung
0.620 0.380 0.000
C34.2 Middle lobe, bronchus or lung
0.620 0.380 0.000
Y57 Other and unspecified drugs and medicaments
0.619 0.380 0.000
T98 Sequelae of other and unspecified effects of external causes
0.619 0.381 0.000
T95 Sequelae of burns, corrosions and frostbite
0.619 0.381 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.619 0.381 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.619 0.381 0.000
C80 Malignant neoplasm without specification of site
0.619 0.381 0.000
H72 Perforation of tympanic membrane
0.619 0.381 0.000
J18.8 Other pneumonia, organism unspecified
0.619 0.381 0.000
J18.2 Hypostatic pneumonia, unspecified
0.619 0.381 0.000
C91 Lymphoid leukaemia
0.618 0.382 0.000
C34.0 Main bronchus
0.618 0.382 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.618 0.382 0.000
D61 Other aplastic anaemias
0.618 0.382 0.000
J15.2 Pneumonia due to staphylococcus
0.618 0.382 0.000
N25-N29 Other disorders of kidney and ureter
0.615 0.385 0.000
H65 Nonsuppurative otitis media
0.615 0.385 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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