TreeWAS – Variant ID: rs115699453

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability
# Top node	1.000	0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.997	0.003
Chapter II Neoplasms	0.981	0.019
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.980	0.020
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.970	0.030
Chapter XX External causes of morbidity and mortality	0.958	0.042
Chapter XIV Diseases of the genitourinary system	0.957	0.043
Chapter I Certain infectious and parasitic diseases	0.953	0.047
Chapter IV Endocrine, nutritional and metabolic diseases	0.953	0.047
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.952	0.048
D60-D64 Aplastic and other anaemias	0.942	0.058
R10-R19 Symptoms and signs involving the digestive system and abdomen	0.927	0.073
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.925	0.075
R00-R09 Symptoms and signs involving the circulatory and respiratory systems	0.923	0.077
Chapter XXI Factors influencing health status and contact with health services	0.912	0.088
E65-E68 Obesity and other hyperalimentation	0.910	0.090
R50-R69 General symptoms and signs	0.909	0.091
R30-R39 Symptoms and signs involving the urinary system	0.908	0.092
D64 Other anaemias	0.905	0.095
C50-C50 Malignant neoplasm of breast	0.904	0.096
B95-B98 Bacterial, viral and other infectious agents	0.896	0.104
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.894	0.106
R10 Abdominal and pelvic pain	0.892	0.108
Chapter XV Pregnancy, childbirth and the puerperium	0.886	0.114
Chapter VI Diseases of the nervous system	0.885	0.115
E66 Obesity	0.880	0.120
D64.9 Anaemia, unspecified	0.879	0.121
R10.4 Other and unspecified abdominal pain	0.876	0.124
M50-M54 Other dorsopathies	0.873	0.127
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.870	0.130
N30-N39 Other diseases of urinary system	0.869	0.131
D50-D53 Nutritional anaemias	0.865	0.135
C15-C26 Malignant neoplasms of digestive organs	0.859	0.141
R33 Retention of urine	0.858	0.142
S60-S69 Injuries to the wrist and hand	0.857	0.143
C50 Malignant neoplasm of breast	0.848	0.152
E70-E90 Metabolic disorders	0.847	0.153
D00-D09 In situ neoplasms	0.845	0.155
Chapter XI Diseases of the digestive system	0.843	0.157
E66.9 Obesity, unspecified	0.843	0.157
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.841	0.159
M20-M25 Other joint disorders	0.834	0.166
Chapter X Diseases of the respiratory system	0.833	0.167
N20-N23 Urolithiasis	0.829	0.171
N17-N19 Renal failure	0.825	0.175
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.811	0.189
Y83.6 Removal of other organ (partial) (total)	0.810	0.190
D10-D36 Benign neoplasms	0.807	0.193
R60 Oedema, not elsewhere classified	0.804	0.196
E83 Disorders of mineral metabolism	0.799	0.201
R00 Abnormalities of heart beat	0.796	0.203
R59 Enlarged lymph nodes	0.795	0.205
A00-A09 Intestinal infectious diseases	0.795	0.205
N10-N16 Renal tubulo-interstitial diseases	0.794	0.206
G40-G47 Episodic and paroxysmal disorders	0.790	0.210
M54 Dorsalgia	0.787	0.213
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters	0.785	0.215
D50 Iron deficiency anaemia	0.782	0.218
C50.9 Breast, unspecified	0.781	0.219
N30 Cystitis	0.780	0.220
B96 Other bacterial agents as the cause of diseases classified to other chapters	0.778	0.222
R02 Gangrene, not elsewhere classified	0.778	0.222
Z40-Z54 Persons encountering health services for specific procedures and health care	0.774	0.226
N25-N29 Other disorders of kidney and ureter	0.774	0.226
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.774	0.226
N32 Other disorders of bladder	0.772	0.228
Z00-Z13 Persons encountering health services for examination and investigation	0.771	0.229
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.770	0.230
E87 Other disorders of fluid, electrolyte and acid-base balance	0.770	0.230
Chapter IX Diseases of the circulatory system	0.769	0.231
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.767	0.233
R47-R49 Symptoms and signs involving speech and voice	0.767	0.233
T15-T19 Effects of foreign body entering through natural orifice	0.765	0.235
R03 Abnormal blood-pressure reading, without diagnosis	0.763	0.237
Y83.3 Surgical operation with formation of external stoma	0.761	0.239
D70-D77 Other diseases of blood and blood-forming organs	0.761	0.239
R13 Dysphagia	0.759	0.241
C64-C68 Malignant neoplasms of urinary tract	0.759	0.241
Chapter VIII Diseases of the ear and mastoid process	0.758	0.242
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.753	0.247
G47 Sleep disorders	0.752	0.248
Chapter XII Diseases of the skin and subcutaneous tissue	0.750	0.250
D37-D48 Neoplasms of uncertain or unknown behaviour	0.750	0.250
R07 Pain in throat and chest	0.748	0.252
S61 Open wound of wrist and hand	0.747	0.253
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.747	0.253
S80-S89 Injuries to the knee and lower leg	0.743	0.257
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.743	0.257
K65-K67 Diseases of peritoneum	0.742	0.258
D63 Anaemia in chronic diseases classified elsewhere	0.742	0.258
M23 Internal derangement of knee	0.742	0.258
C73 Malignant neoplasm of thyroid gland	0.740	0.260
D05 Carcinoma in situ of breast	0.738	0.262
E66.8 Other obesity	0.735	0.265
O20-O29 Other maternal disorders predominantly related to pregnancy	0.733	0.267
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.732	0.268
N20 Calculus of kidney and ureter	0.731	0.269
N18 Chronic renal failure	0.730	0.270
R60.0 Localised oedema	0.728	0.272
R61 Hyperhidrosis	0.725	0.275
M65-M68 Disorders of synovium and tendon	0.725	0.275
M15-M19 Arthrosis	0.722	0.278
I60-I69 Cerebrovascular diseases	0.721	0.279
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.721	0.279
T81 Complications of procedures, not elsewhere classified	0.720	0.280
K55-K64 Other diseases of intestines	0.720	0.280
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.720	0.280
M05-M14 Inflammatory polyarthropathies	0.719	0.280
R39 Other symptoms and signs involving the urinary system	0.718	0.282
Chapter XXII Codes for special purposes	0.717	0.283
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
C15 Malignant neoplasm of oesophagus	0.716	0.284
R95-R99 Ill-defined and unknown causes of mortality	0.715	0.285
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.715	0.285
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.714	0.286
A30-A49 Other bacterial diseases	0.713	0.287
C50.1 Central portion of breast	0.713	0.287
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.712	0.288
Y84.2 Radiological procedure and radiotherapy	0.711	0.289
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue	0.710	0.290
Y83.1 Surgical operation with implant of artificial internal device	0.709	0.291
M51 Other intervertebral disk disorders	0.708	0.292
T36-T50 Poisoning by drugs, medicaments and biological substances	0.704	0.296
B95.4 Other streptococcus as the cause of diseases classified to other chapters	0.704	0.296
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.703	0.297
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.703	0.297
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.703	0.297
C40-C41 Malignant neoplasms of bone and articular cartilage	0.703	0.297
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.703	0.297
D80-D89 Certain disorders involving the immune mechanism	0.703	0.297
D55-D59 Haemolytic anaemias	0.703	0.297
T85 Complications of other internal prosthetic devices, implants and grafts	0.703	0.297
D17 Benign lipomatous neoplasm	0.702	0.298
R53 Malaise and fatigue	0.698	0.302
R54 Senility	0.697	0.302
R12 Heartburn	0.696	0.304
O94-O99 Other obstetric conditions, not elsewhere classified	0.696	0.304
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.696	0.304
T79-T79 Certain early complications of trauma	0.696	0.304
T66-T78 Other and unspecified effects of external causes	0.696	0.304
T33-T35 Frostbite	0.696	0.304
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.696	0.304
T26-T28 Burns and corrosions confined to eye and internal organs	0.696	0.304
T20-T25 Burns and corrosions of external body surface, specified by site	0.696	0.304
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.696	0.304
T00-T07 Injuries involving multiple body regions	0.696	0.304
S90-S99 Injuries to the ankle and foot	0.696	0.304
S70-S79 Injuries to the hip and thigh	0.696	0.304
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.696	0.304
S20-S29 Injuries to the thorax	0.696	0.304
S10-S19 Injuries to the neck	0.696	0.304
R15 Faecal incontinence	0.695	0.305
D50.9 Iron deficiency anaemia, unspecified	0.693	0.307
S40-S49 Injuries to the shoulder and upper arm	0.692	0.307
B98 Other specified infectious agents as the cause of diseases classified to other chapters	0.692	0.308
N60-N64 Disorders of breast	0.689	0.311
W00-W19 Falls	0.688	0.311
R01 Cardiac murmurs and other cardiac sounds	0.688	0.312
B35-B49 Mycoses	0.687	0.313
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.687	0.313
Y60-Y69 Misadventures to patients during surgical and medical care	0.687	0.313
Y35-Y36 Legal intervention and operations of war	0.687	0.313
Y10-Y34 Event of undetermined intent	0.687	0.313
Y00-Y09 Assault	0.687	0.313
X85-X99 Assault	0.687	0.313
X60-X84 Intentional self-harm	0.687	0.313
X58-X59 Accidental exposure to other and unspecified factors	0.687	0.313
X50-X57 Overexertion, travel and privation	0.687	0.313
X40-X49 Accidental poisoning by and exposure to noxious substances	0.687	0.313
X30-X39 Exposure to forces of nature	0.687	0.313
X20-X29 Contact with venomous animals and plants	0.687	0.313
X10-X19 Contact with heat and hot substances	0.687	0.313
X00-X09 Exposure to smoke, fire and flames	0.687	0.313
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.687	0.313
W75-W84 Other accidental threats to breathing	0.687	0.313
W65-W74 Accidental drowning and submersion	0.687	0.313
W50-W64 Exposure to animate mechanical forces	0.687	0.313
W20-W49 Exposure to inanimate mechanical forces	0.687	0.313
V98-V99 Other and unspecified transport accidents	0.687	0.313
V95-V97 Air and space transport accidents	0.687	0.313
V90-V94 Water transport accidents	0.687	0.313
V80-V89 Other land transport accidents	0.687	0.313
V70-V79 Bus occupant injured in transport accident	0.687	0.313
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.687	0.313
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.687	0.313
V40-V49 Car occupant injured in transport accident	0.687	0.313
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.687	0.313
V20-V29 Motorcycle rider injured in transport accident	0.687	0.313
V10-V19 Pedal cyclist injured in transport accident	0.687	0.313
V01-V09 Pedestrian injured in transport accident	0.687	0.313
G35-G37 Demyelinating diseases of the central nervous system	0.687	0.313
J40-J47 Chronic lower respiratory diseases	0.687	0.313
R50 Fever of unknown origin	0.686	0.314
N99-N99 Other disorders of the genitourinary system	0.686	0.314
R18 Ascites	0.685	0.315
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.684	0.316
B99-B99 Other infectious diseases	0.683	0.317
B90-B94 Sequelae of infectious and parasitic diseases	0.683	0.317
B85-B89 Pediculosis, acariasis and other infestations	0.683	0.317
B65-B83 Helminthiases	0.683	0.317
B50-B64 Protozoal diseases	0.683	0.317
B20-B24 Human immunodeficiency virus [HIV] disease	0.683	0.317
B15-B19 Viral hepatitis	0.683	0.317
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.683	0.317
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.683	0.317
A80-A89 Viral infections of the central nervous system	0.683	0.317
A75-A79 Rickettsioses	0.683	0.317
A70-A74 Other diseases caused by chlamydiae	0.683	0.317
A65-A69 Other spirochaetal diseases	0.683	0.317
A50-A64 Infections with a predominantly sexual mode of transmission	0.683	0.317
A20-A28 Certain zoonotic bacterial diseases	0.683	0.317
A15-A19 Tuberculosis	0.683	0.317
E83.4 Disorders of magnesium metabolism	0.683	0.317
E40-E46 Malnutrition	0.683	0.317
E20-E35 Disorders of other endocrine glands	0.683	0.317
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.683	0.317
M91-M94 Chondropathies	0.683	0.317
M86-M90 Other osteopathies	0.683	0.317
M60-M63 Disorders of muscles	0.683	0.317
M00-M03 Infectious arthropathies	0.683	0.317
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.682	0.317
R31 Unspecified haematuria	0.679	0.321
M70-M79 Other soft tissue disorders	0.679	0.321
K40-K46 Hernia	0.679	0.321
E83.5 Disorders of calcium metabolism	0.679	0.321
E50-E64 Other nutritional deficiencies	0.678	0.322
G47.3 Sleep apnoea	0.678	0.322
R05 Cough	0.677	0.323
R10.3 Pain localised to other parts of lower abdomen	0.677	0.323
S64 Injury of nerves at wrist and hand level	0.677	0.323
C16 Malignant neoplasm of stomach	0.676	0.324
G47.9 Sleep disorder, unspecified	0.676	0.324
D61 Other aplastic anaemias	0.675	0.325
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.675	0.325
D62 Acute posthaemorrhagic anaemia	0.675	0.325
M40-M43 Deforming dorsopathies	0.675	0.325
N00-N08 Glomerular diseases	0.674	0.326
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.674	0.326
R00.2 Palpitations	0.674	0.326
D24 Benign neoplasm of breast	0.674	0.326
N30.9 Cystitis, unspecified	0.673	0.327
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms	0.673	0.327
R56 Convulsions, not elsewhere classified	0.673	0.327
E83.1 Disorders of iron metabolism	0.671	0.329
S61.0 Open wound of finger(s) without damage to nail	0.669	0.331
R70-R79 Abnormal findings on examination of blood, without diagnosis	0.669	0.331
R00.0 Tachycardia, unspecified	0.668	0.332
R07.4 Chest pain, unspecified	0.667	0.333
M54.2 Cervicalgia	0.666	0.334
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis	0.665	0.334
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters	0.665	0.335
O00-O08 Pregnancy with abortive outcome	0.665	0.335
R16 Hepatomegaly and splenomegaly, not elsewhere classified	0.664	0.336
R17 Unspecified jaundice	0.664	0.336
Z60 Problems related to social environment	0.663	0.337
E87.6 Hypokalaemia	0.662	0.338
I67 Other cerebrovascular diseases	0.662	0.338
R09 Other symptoms and signs involving the circulatory and respiratory systems	0.662	0.338
R59.1 Generalised enlarged lymph nodes	0.660	0.340
M25 Other joint disorders, not elsewhere classified	0.659	0.341
R59.0 Localised enlarged lymph nodes	0.658	0.342
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis	0.657	0.343
Chapter VII Diseases of the eye and adnexa	0.656	0.344
M23.2 Derangement of meniscus due to old tear or injury	0.656	0.344
N32.8 Other specified disorders of bladder	0.654	0.345
C51-C58 Malignant neoplasms of female genital organs	0.654	0.346
K50-K52 Noninfective enteritis and colitis	0.654	0.346
Z51 Other medical care	0.653	0.347
E67 Other hyperalimentation	0.653	0.347
E68 Sequelae of hyperalimentation	0.653	0.347
E65 Localised adiposity	0.653	0.347
J90-J94 Other diseases of pleura	0.653	0.347
C19 Malignant neoplasm of rectosigmoid junction	0.652	0.348
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.652	0.348
J80-J84 Other respiratory diseases principally affecting the interstitium	0.652	0.348
R68 Other general symptoms and signs	0.652	0.348
R65 Systemic Inflammatory Response Syndrome [SIRS]	0.652	0.348
R62 Lack of expected normal physiological development	0.652	0.348
R57 Shock, not elsewhere classified	0.652	0.348
R64 Cachexia	0.652	0.348
R58 Haemorrhage, not elsewhere classified	0.652	0.348
R36 Urethral discharge	0.651	0.349
R34 Anuria and oliguria	0.651	0.349
S00-S09 Injuries to the head	0.651	0.349
J00-J06 Acute upper respiratory infections	0.649	0.351
D64.8 Other specified anaemias	0.649	0.351
D64.4 Congenital dyserythropoietic anaemia	0.649	0.351
D64.3 Other sideroblastic anaemias	0.649	0.351
D64.2 Secondary sideroblastic anaemia due to drugs and toxins	0.649	0.351
D64.1 Secondary sideroblastic anaemia due to disease	0.649	0.351
D64.0 Hereditary sideroblastic anaemia	0.649	0.351
N12 Tubulo-interstitial nephritis, not specified as acute or chronic	0.648	0.352
B25-B34 Other viral diseases	0.648	0.352
E87.5 Hyperkalaemia	0.648	0.352
A09 Diarrhoea and gastro-enteritis of presumed infectious origin	0.648	0.352
N30.2 Other chronic cystitis	0.648	0.352
S50-S59 Injuries to the elbow and forearm	0.646	0.353
R52 Pain, not elsewhere classified	0.645	0.355
C50.2 Upper-inner quadrant of breast	0.645	0.355
M54.9 Dorsalgia, unspecified	0.645	0.355
C18 Malignant neoplasm of colon	0.644	0.356
M80-M85 Disorders of bone density and structure	0.643	0.357
D32 Benign neoplasm of meninges	0.643	0.357
N28 Other disorders of kidney and ureter, not elsewhere classified	0.643	0.357
O80-O84 Delivery	0.642	0.358
B97 Viral agents as the cause of diseases classified to other chapters	0.642	0.358
R32 Unspecified urinary incontinence	0.642	0.358
Y43 Primarily systemic agents	0.642	0.358
K66 Other disorders of peritoneum	0.642	0.358
T88 Other complications of surgical and medical care, not elsewhere classified	0.641	0.359
T87 Complications peculiar to reattachment and amputation	0.641	0.359
T86 Failure and rejection of transplanted organs and tissues	0.641	0.359
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.641	0.359
T80 Complications following infusion, transfusion and therapeutic injection	0.641	0.359
R10.0 Acute abdomen	0.640	0.360
N32.3 Diverticulum of bladder	0.637	0.363
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.636	0.364
C64 Malignant neoplasm of kidney, except renal pelvis	0.635	0.365
O85-O92 Complications predominantly related to the puerperium	0.635	0.365
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.635	0.365
G70-G73 Diseases of myoneural junction and muscle	0.635	0.365
G30-G32 Other degenerative diseases of the nervous system	0.635	0.365
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.635	0.365
G00-G09 Inflammatory diseases of the central nervous system	0.635	0.365
N35 Urethral stricture	0.633	0.367
D50.8 Other iron deficiency anaemias	0.633	0.367
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.632	0.368
E66.2 Extreme obesity with alveolar hypoventilation	0.631	0.369
E66.1 Drug-induced obesity	0.631	0.369
E66.0 Obesity due to excess calories	0.631	0.369
E87.7 Fluid overload	0.630	0.370
N20.0 Calculus of kidney	0.629	0.371
Z42 Follow-up care involving plastic surgery	0.628	0.372
K90-K93 Other diseases of the digestive system	0.628	0.372
G80-G83 Cerebral palsy and other paralytic syndromes	0.627	0.373
G20-G26 Extrapyramidal and movement disorders	0.626	0.374
D06 Carcinoma in situ of cervix uteri	0.626	0.374
N32.9 Bladder disorder, unspecified	0.626	0.374
M53 Other dorsopathies, not elsewhere classified	0.626	0.374
M50 Cervical disk disorders	0.626	0.374
Z46 Fitting and adjustment of other devices	0.625	0.375
Y84.8 Other medical procedures	0.624	0.376
Y83.9 Surgical procedure, unspecified	0.624	0.376
Y83.5 Amputation of limb(s)	0.624	0.376
Y83.4 Other reconstructive surgery	0.624	0.376
Y83.0 Surgical operation with transplant of whole organ	0.624	0.376
D35 Benign neoplasm of other and unspecified endocrine glands	0.624	0.376
D51 Vitamin B12 deficiency anaemia	0.623	0.376
N37 Urethral disorders in diseases classified elsewhere	0.623	0.377
N36 Other disorders of urethra	0.623	0.377
N34 Urethritis and urethral syndrome	0.623	0.377
N33 Bladder disorders in diseases classified elsewhere	0.623	0.377
D05.9 Carcinoma in situ of breast, unspecified	0.623	0.377
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters	0.623	0.377
K56 Paralytic ileus and intestinal obstruction without hernia	0.622	0.378
I63 Cerebral infarction	0.621	0.379
A04 Other bacterial intestinal infections	0.621	0.379
D53 Other nutritional anaemias	0.620	0.379
D52 Folate deficiency anaemia	0.620	0.379
D23 Other benign neoplasms of skin	0.620	0.379
T17 Foreign body in respiratory tract	0.618	0.382
C26 Malignant neoplasm of other and ill-defined digestive organs	0.616	0.384
C25 Malignant neoplasm of pancreas	0.616	0.384
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.616	0.384
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.616	0.384
C21 Malignant neoplasm of anus and anal canal	0.616	0.384
C17 Malignant neoplasm of small intestine	0.616	0.384
C23 Malignant neoplasm of gallbladder	0.616	0.384
K42 Umbilical hernia	0.616	0.384
R63 Symptoms and signs concerning food and fluid intake	0.615	0.385
K60 Fissure and fistula of anal and rectal regions	0.615	0.385
S69 Other and unspecified injuries of wrist and hand	0.614	0.386
S68 Traumatic amputation of wrist and hand	0.614	0.386
S67 Crushing injury of wrist and hand	0.614	0.386
S66 Injury of muscle and tendon at wrist and hand level	0.614	0.386
S65 Injury of blood vessels at wrist and hand level	0.614	0.386
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.614	0.386
S62 Fracture at wrist and hand level	0.614	0.386
S60 Superficial injury of wrist and hand	0.614	0.386
N13 Obstructive and reflux uropathy	0.614	0.386
R03.0 Elevated blood-pressure reading, without diagnosis of hypertension	0.614	0.386
N31 Neuromuscular dysfunction of bladder, not elsewhere classified	0.612	0.387
S81 Open wound of lower leg	0.612	0.387
N19 Unspecified renal failure	0.612	0.388
R04 Haemorrhage from respiratory passages	0.612	0.388
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.612	0.388
J47 Bronchiectasis	0.611	0.389
G90-G99 Other disorders of the nervous system	0.611	0.389
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts	0.610	0.390
N23 Unspecified renal colic	0.610	0.390
Z48 Other surgical follow-up care	0.609	0.391
N18.3 Chronic kidney disease, stage 3	0.609	0.391
C60-C63 Malignant neoplasms of male genital organs	0.609	0.391
J95-J99 Other diseases of the respiratory system	0.609	0.391
Z45 Adjustment and management of implanted device	0.608	0.392
C50.8 Overlapping lesion of breast	0.608	0.392
C50.6 Axillary tail of breast	0.608	0.392
C50.5 Lower-outer quadrant of breast	0.608	0.392
C50.3 Lower-inner quadrant of breast	0.608	0.392
C50.0 Nipple and areola	0.608	0.392
E88 Other metabolic disorders	0.607	0.392
E85 Amyloidosis	0.607	0.392
E84 Cystic fibrosis	0.607	0.392
E80 Disorders of porphyrin and bilirubin metabolism	0.607	0.392
E79 Disorders of purine and pyrimidine metabolism	0.607	0.392
E77 Disorders of glycoprotein metabolism	0.607	0.392
E76 Disorders of glycosaminoglycan metabolism	0.607	0.392
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.607	0.392
E74 Other disorders of carbohydrate metabolism	0.607	0.392
E73 Lactose intolerance	0.607	0.392
E72 Other disorders of amino-acid metabolism	0.607	0.392
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.607	0.392
E70 Disorders of aromatic amino-acid metabolism	0.607	0.392
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.607	0.392
M54.3 Sciatica	0.607	0.393
D09 Carcinoma in situ of other and unspecified sites	0.606	0.394
D07 Carcinoma in situ of other and unspecified genital organs	0.606	0.394
D04 Carcinoma in situ of skin	0.606	0.394
D03 Melanoma in situ	0.606	0.394
D02 Carcinoma in situ of middle ear and respiratory system	0.606	0.394
D01 Carcinoma in situ of other and unspecified digestive organs	0.606	0.394
D00 Carcinoma in situ of oral cavity, oesophagus and stomach	0.606	0.394
R26 Abnormalities of gait and mobility	0.604	0.395
O26 Maternal care for other conditions predominantly related to pregnancy	0.604	0.396
D70 Agranulocytosis	0.603	0.397
T81.3 Disruption of operation wound, not elsewhere classified	0.603	0.397
C75 Malignant neoplasm of other endocrine glands and related structures	0.603	0.397
C74 Malignant neoplasm of adrenal gland	0.603	0.397
L00-L08 Infections of the skin and subcutaneous tissue	0.603	0.397
Z22 Carrier of infectious disease	0.602	0.398
Z70-Z76 Persons encountering health services in other circumstances	0.601	0.399
M45-M49 Spondylopathies	0.600	0.400
C20 Malignant neoplasm of rectum	0.600	0.400
E10-E14 Diabetes mellitus	0.599	0.401
D63.8 Anaemia in other chronic diseases classified elsewhere	0.598	0.401
D05.1 Intraductal carcinoma in situ	0.598	0.401
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.598	0.402
M34 Systemic sclerosis	0.598	0.402
M33 Dermatopolymyositis	0.598	0.402
M32 Systemic lupus erythematosus	0.598	0.402
M31 Other necrotising vasculopathies	0.598	0.402
M30 Polyarteritis nodosa and related conditions	0.598	0.402
M24 Other specific joint derangements	0.598	0.402
M22 Disorders of patella	0.598	0.402
M21 Other acquired deformities of limbs	0.598	0.402
J30-J39 Other diseases of upper respiratory tract	0.598	0.402
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.598	0.402
J60-J70 Lung diseases due to external agents	0.598	0.402
R51 Headache	0.597	0.403
R47 Speech disturbances, not elsewhere classified	0.597	0.403
R03.1 Nonspecific low blood-pressure reading	0.596	0.404
N22 Calculus of urinary tract in diseases classified elsewhere	0.594	0.406
N21 Calculus of lower urinary tract	0.594	0.406
K70-K77 Diseases of liver	0.594	0.406
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status	0.594	0.406
R61.9 Hyperhidrosis, unspecified	0.593	0.406
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.593	0.407
K65 Peritonitis	0.592	0.408
R19 Other symptoms and signs involving the digestive system and abdomen	0.591	0.409
M51.2 Other specified intervertebral disk displacement	0.590	0.410
D17.1 Benign lipomatous neoplasm of skin and subcutaneous tissue of trunk	0.590	0.410
Z50 Care involving use of rehabilitation procedures	0.589	0.411
R39.8 Other and unspecified symptoms and signs involving the urinary system	0.589	0.411
R41 Other symptoms and signs involving cognitive functions and awareness	0.588	0.412
Z60.2 Living alone	0.588	0.412
R30 Pain associated with micturition	0.588	0.412
N20.1 Calculus of ureter	0.587	0.413
T51 Toxic effect of alcohol	0.587	0.413
I67.9 Cerebrovascular disease, unspecified	0.586	0.414
O60-O75 Complications of labour and delivery	0.585	0.415
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis	0.584	0.416
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters	0.584	0.416
K35-K38 Diseases of appendix	0.584	0.416
Z08 Follow-up examination after treatment for malignant neoplasm	0.584	0.416
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.584	0.416
Z51.1 Chemotherapy session for neoplasm	0.582	0.418
Y84.9 Medical procedure, unspecified	0.581	0.418
Y84.7 Blood-sampling	0.581	0.418
Y84.6 Urinary catheterisation	0.581	0.418
Y84.5 Insertion of gastric or duodenal sound	0.581	0.418
Y84.4 Aspiration of fluid	0.581	0.418
Y84.3 Shock therapy	0.581	0.418
Y84.1 Kidney dialysis	0.581	0.418
Y84.0 Cardiac catheterisation	0.581	0.418
R55 Syncope and collapse	0.581	0.419
M23.3 Other meniscus derangements	0.580	0.420
M54.22 Cervicalgia (Cervical region)	0.580	0.420
D36 Benign neoplasm of other and unspecified sites	0.579	0.421
D33 Benign neoplasm of brain and other parts of central nervous system	0.579	0.421
D31 Benign neoplasm of eye and adnexa	0.579	0.421
D30 Benign neoplasm of urinary organs	0.579	0.421
D29 Benign neoplasm of male genital organs	0.579	0.421
D28 Benign neoplasm of other and unspecified female genital organs	0.579	0.421
D26 Other benign neoplasms of uterus	0.579	0.421
D21 Other benign neoplasms of connective and other soft tissue	0.579	0.421
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum	0.579	0.421
D19 Benign neoplasm of mesothelial tissue	0.579	0.421
D16 Benign neoplasm of bone and articular cartilage	0.579	0.421
D15 Benign neoplasm of other and unspecified intrathoracic organs	0.579	0.421

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations