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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs115706318
log Bayes Factor = 11.1749
Chromosome 2   position 97,143,761  (GRCh37) Explore rs115706318 on Ensembl!
Variant rs115706318 is part of Cluster X0075

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter VII Diseases of the eye and adnexa
0.999 0.001 0.000
Chapter II Neoplasms
0.999 0.001 0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal
0.998 0.002 0.000
Chapter XX External causes of morbidity and mortality
0.998 0.002 0.000
D10-D36 Benign neoplasms
0.997 0.003 0.000
C15-C26 Malignant neoplasms of digestive organs
0.995 0.005 0.000
Chapter X Diseases of the respiratory system
0.995 0.005 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.995 0.005 0.000
H30-H36 Disorders of choroid and retina
0.989 0.011 0.000
J95-J99 Other diseases of the respiratory system
0.988 0.012 0.000
J98 Other respiratory disorders
0.985 0.015 0.000
Chapter VI Diseases of the nervous system
0.983 0.017 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.980 0.020 0.000
D12.3 Transverse colon
0.975 0.025 0.000
J98.4 Other disorders of lung
0.974 0.026 0.000
G40-G47 Episodic and paroxysmal disorders
0.972 0.028 0.000
C18 Malignant neoplasm of colon
0.967 0.033 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.963 0.037 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.960 0.040 0.000
D12.5 Sigmoid colon
0.960 0.040 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.959 0.041 0.000
H35 Other retinal disorders
0.954 0.046 0.000
D12.2 Ascending colon
0.950 0.050 0.000
W00-W19 Falls
0.949 0.051 0.000
R42 Dizziness and giddiness
0.940 0.060 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.938 0.062 0.000
H33 Retinal detachments and breaks
0.937 0.063 0.000
Chapter V Mental and behavioural disorders
0.936 0.064 0.000
D25 Leiomyoma of uterus
0.935 0.065 0.000
G43 Migraine
0.931 0.069 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.924 0.076 0.000
O60-O75 Complications of labour and delivery
0.922 0.078 0.000
H25-H28 Disorders of lens
0.920 0.080 0.000
H33.3 Retinal breaks without detachment
0.916 0.084 0.000
W19 Unspecified fall
0.915 0.085 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.913 0.087 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.912 0.088 0.000
D25.2 Subserosal leiomyoma of uterus
0.909 0.091 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.906 0.094 0.000
O72 Postpartum haemorrhage
0.899 0.101 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.897 0.103 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.896 0.104 0.000
G43.9 Migraine, unspecified
0.896 0.104 0.000
Chapter IX Diseases of the circulatory system
0.894 0.106 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.892 0.108 0.000
F20 Schizophrenia
0.890 0.110 0.000
G44 Other headache syndromes
0.889 0.111 0.000
D12.0 Caecum
0.887 0.113 0.000
W19.9 Unspecified place
0.885 0.115 0.000
Chapter VIII Diseases of the ear and mastoid process
0.882 0.118 0.000
T93 Sequelae of injuries of lower limb
0.880 0.120 0.000
O72.1 Other immediate postpartum haemorrhage
0.876 0.124 0.000
C15 Malignant neoplasm of oesophagus
0.876 0.124 0.000
H25 Senile cataract
0.872 0.128 0.000
I30-I52 Other forms of heart disease
0.871 0.129 0.000
J00-J06 Acute upper respiratory infections
0.869 0.131 0.000
H43-H45 Disorders of vitreous body and globe
0.868 0.131 0.000
R47-R49 Symptoms and signs involving speech and voice
0.868 0.132 0.000
C18.0 Caecum
0.865 0.135 0.000
D25.1 Intramural leiomyoma of uterus
0.864 0.136 0.000
F20.9 Schizophrenia, unspecified
0.863 0.137 0.000
C18.9 Colon, unspecified
0.860 0.140 0.000
W20-W49 Exposure to inanimate mechanical forces
0.857 0.143 0.000
D14 Benign neoplasm of middle ear and respiratory system
0.856 0.144 0.000
H35.3 Degeneration of macula and posterior pole
0.852 0.148 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.852 0.148 0.000
Y95 Nosocomial condition
0.850 0.150 0.000
H35.8 Other specified retinal disorders
0.849 0.151 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.846 0.154 0.000
S50-S59 Injuries to the elbow and forearm
0.846 0.154 0.000
C17 Malignant neoplasm of small intestine
0.844 0.156 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.841 0.159 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.841 0.159 0.000
R05 Cough
0.839 0.161 0.000
G45.9 Transient cerebral ischaemic attack, unspecified
0.838 0.162 0.000
D12.4 Descending colon
0.838 0.162 0.000
I60-I69 Cerebrovascular diseases
0.836 0.164 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.836 0.164 0.000
R04 Haemorrhage from respiratory passages
0.831 0.169 0.000
H25.0 Senile incipient cataract
0.831 0.169 0.000
G44.2 Tension-type headache
0.829 0.171 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.828 0.172 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.827 0.173 0.000
R01 Cardiac murmurs and other cardiac sounds
0.824 0.176 0.000
J09-J18 Influenza and pneumonia
0.819 0.181 0.000
I51 Complications and ill-defined descriptions of heart disease
0.818 0.182 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.817 0.182 0.000
J30-J39 Other diseases of upper respiratory tract
0.814 0.186 0.000
D26 Other benign neoplasms of uterus
0.813 0.187 0.000
I49 Other cardiac arrhythmias
0.813 0.187 0.000
J90-J94 Other diseases of pleura
0.813 0.187 0.000
Chapter XXII Codes for special purposes
0.811 0.188 0.000
D12.9 Anus and anal canal
0.811 0.189 0.000
J98.0 Diseases of bronchus, not elsewhere classified
0.811 0.189 0.000
J98.1 Pulmonary collapse
0.810 0.190 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.808 0.192 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.806 0.194 0.000
R09.1 Pleurisy
0.803 0.197 0.000
D12.7 Rectosigmoid junction
0.802 0.198 0.000
S90-S99 Injuries to the ankle and foot
0.800 0.200 0.000
G20-G26 Extrapyramidal and movement disorders
0.798 0.202 0.000
H25.1 Senile nuclear cataract
0.797 0.203 0.000
R04.2 Haemoptysis
0.795 0.205 0.000
C18.4 Transverse colon
0.794 0.206 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.792 0.208 0.000
D21 Other benign neoplasms of connective and other soft tissue
0.791 0.209 0.000
S10-S19 Injuries to the neck
0.791 0.209 0.000
V10-V19 Pedal cyclist injured in transport accident
0.791 0.209 0.000
X60-X84 Intentional self-harm
0.790 0.210 0.000
J98.5 Diseases of mediastinum, not elsewhere classified
0.788 0.212 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.787 0.213 0.000
O47 False labour
0.787 0.213 0.000
R47 Speech disturbances, not elsewhere classified
0.785 0.215 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.784 0.216 0.000
V40-V49 Car occupant injured in transport accident
0.784 0.216 0.000
I51.7 Cardiomegaly
0.784 0.216 0.000
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium
0.782 0.218 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.782 0.218 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.781 0.219 0.000
O36 Maternal care for other known or suspected foetal problems
0.780 0.220 0.000
C18.6 Descending colon
0.779 0.221 0.000
R03.1 Nonspecific low blood-pressure reading
0.779 0.221 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.778 0.222 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.778 0.222 0.000
T93.2 Sequelae of other fractures of lower limb
0.778 0.222 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.776 0.224 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.775 0.225 0.000
H35.0 Background retinopathy and retinal vascular changes
0.773 0.227 0.000
I67 Other cerebrovascular diseases
0.771 0.229 0.000
Chapter XXI Factors influencing health status and contact with health services
0.770 0.230 0.000
D36 Benign neoplasm of other and unspecified sites
0.770 0.230 0.000
T91 Sequelae of injuries of neck and trunk
0.769 0.231 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.769 0.231 0.000
H33.1 Retinoschisis and retinal cysts
0.767 0.233 0.000
D31 Benign neoplasm of eye and adnexa
0.767 0.233 0.000
S00-S09 Injuries to the head
0.764 0.236 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.763 0.237 0.000
H60-H62 Diseases of external ear
0.763 0.237 0.000
S40-S49 Injuries to the shoulder and upper arm
0.761 0.238 0.000
R45 Symptoms and signs involving emotional state
0.761 0.239 0.000
C21 Malignant neoplasm of anus and anal canal
0.760 0.240 0.000
T92 Sequelae of injuries of upper limb
0.759 0.241 0.000
H35.9 Retinal disorder, unspecified
0.759 0.241 0.000
W50-W64 Exposure to animate mechanical forces
0.757 0.243 0.000
H65-H75 Diseases of middle ear and mastoid
0.757 0.243 0.000
I47 Paroxysmal tachycardia
0.755 0.245 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.754 0.246 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.754 0.246 0.000
H43 Disorders of vitreous body
0.754 0.246 0.000
D12.8 Rectum
0.750 0.250 0.000
X50-X57 Overexertion, travel and privation
0.749 0.251 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.746 0.254 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.745 0.255 0.000
O72.2 Delayed and secondary postpartum haemorrhage
0.745 0.255 0.000
H31 Other disorders of choroid
0.745 0.255 0.000
D28 Benign neoplasm of other and unspecified female genital organs
0.745 0.255 0.000
W19.4 Street and highway
0.743 0.257 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.743 0.257 0.000
W19.1 Residential institution
0.742 0.258 0.000
C51-C58 Malignant neoplasms of female genital organs
0.741 0.258 0.000
D10 Benign neoplasm of mouth and pharynx
0.741 0.259 0.000
D14.1 Larynx
0.741 0.259 0.000
C16 Malignant neoplasm of stomach
0.738 0.262 0.000
F80-F89 Disorders of psychological development
0.738 0.262 0.000
H55-H59 Other disorders of eye and adnexa
0.735 0.265 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.735 0.265 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.734 0.265 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.733 0.267 0.000
F20.0 Paranoid schizophrenia
0.732 0.268 0.000
O41 Other disorders of amniotic fluid and membranes
0.732 0.268 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.732 0.268 0.000
R06 Abnormalities of breathing
0.731 0.269 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.731 0.269 0.000
H53-H54 Visual disturbances and blindness
0.730 0.270 0.000
C15.9 Oesophagus, unspecified
0.729 0.271 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.729 0.271 0.000
S09 Other and unspecified injuries of head
0.729 0.271 0.000
D34 Benign neoplasm of thyroid gland
0.728 0.272 0.000
D50-D53 Nutritional anaemias
0.728 0.272 0.000
C18.2 Ascending colon
0.726 0.274 0.000
R01.1 Cardiac murmur, unspecified
0.726 0.274 0.000
Y52 Agents primarily affecting the cardiovascular system
0.724 0.276 0.000
Y45.0 Opioids and related analgesics
0.721 0.279 0.000
R09.0 Asphyxia
0.721 0.279 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.720 0.280 0.000
W22 Striking against or struck by other objects
0.720 0.280 0.000
C49 Malignant neoplasm of other connective and soft tissue
0.719 0.281 0.000
O30 Multiple gestation
0.719 0.281 0.000
G43.1 Migraine with aura [classical migraine]
0.719 0.281 0.000
R09.3 Abnormal sputum
0.718 0.282 0.000
O00-O08 Pregnancy with abortive outcome
0.717 0.283 0.000
I49.9 Cardiac arrhythmia, unspecified
0.717 0.283 0.000
W07 Fall involving chair
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
D11 Benign neoplasm of major salivary glands
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.716 0.284 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.716 0.284 0.000
S51 Open wound of forearm
0.716 0.284 0.000
D12.1 Appendix
0.716 0.284 0.000
T98 Sequelae of other and unspecified effects of external causes
0.715 0.284 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.715 0.284 0.000
Y35-Y36 Legal intervention and operations of war
0.715 0.284 0.000
Y10-Y34 Event of undetermined intent
0.715 0.284 0.000
Y00-Y09 Assault
0.715 0.284 0.000
X85-X99 Assault
0.715 0.284 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.715 0.284 0.000
X30-X39 Exposure to forces of nature
0.715 0.284 0.000
X20-X29 Contact with venomous animals and plants
0.715 0.284 0.000
X10-X19 Contact with heat and hot substances
0.715 0.284 0.000
X00-X09 Exposure to smoke, fire and flames
0.715 0.284 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.715 0.284 0.000
W75-W84 Other accidental threats to breathing
0.715 0.284 0.000
W65-W74 Accidental drowning and submersion
0.715 0.284 0.000
V98-V99 Other and unspecified transport accidents
0.715 0.284 0.000
V95-V97 Air and space transport accidents
0.715 0.284 0.000
V90-V94 Water transport accidents
0.715 0.284 0.000
V80-V89 Other land transport accidents
0.715 0.284 0.000
V70-V79 Bus occupant injured in transport accident
0.715 0.284 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.715 0.284 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.715 0.284 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.715 0.284 0.000
V01-V09 Pedestrian injured in transport accident
0.715 0.284 0.000
D30 Benign neoplasm of urinary organs
0.715 0.285 0.000
D29 Benign neoplasm of male genital organs
0.715 0.285 0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum
0.715 0.285 0.000
D19 Benign neoplasm of mesothelial tissue
0.715 0.285 0.000
D16 Benign neoplasm of bone and articular cartilage
0.715 0.285 0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs
0.715 0.285 0.000
Z72 Problems related to lifestyle
0.715 0.285 0.000
J38.7 Other diseases of larynx
0.714 0.286 0.000
Y40 Systemic antibiotics
0.714 0.286 0.000
G45.4 Transient global amnesia
0.714 0.286 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.713 0.287 0.000
C23 Malignant neoplasm of gallbladder
0.713 0.287 0.000
O85-O92 Complications predominantly related to the puerperium
0.713 0.287 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.712 0.288 0.000
T93.1 Sequelae of fracture of femur
0.710 0.290 0.000
G70-G73 Diseases of myoneural junction and muscle
0.710 0.290 0.000
J93 Pneumothorax
0.710 0.290 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.709 0.291 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.709 0.291 0.000
H30 Chorioretinal inflammation
0.709 0.291 0.000
F29 Unspecified nonorganic psychosis
0.709 0.291 0.000
J96 Respiratory failure, not elsewhere classified
0.709 0.291 0.000
T90 Sequelae of injuries of head
0.708 0.292 0.000
H35.5 Hereditary retinal dystrophy
0.708 0.292 0.000
H52 Disorders of refraction and accommodation
0.708 0.292 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.707 0.293 0.000
I67.8 Other specified cerebrovascular diseases
0.706 0.294 0.000
J98.9 Respiratory disorder, unspecified
0.706 0.294 0.000
J98.8 Other specified respiratory disorders
0.706 0.294 0.000
J98.6 Disorders of diaphragm
0.706 0.294 0.000
J98.3 Compensatory emphysema
0.706 0.294 0.000
J98.2 Interstitial emphysema
0.706 0.294 0.000
O80-O84 Delivery
0.706 0.294 0.000
W06 Fall involving bed
0.704 0.296 0.000
S09.9 Unspecified injury of head
0.704 0.296 0.000
Z72.0 Tobacco use
0.703 0.297 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.703 0.297 0.000
F30-F39 Mood [affective] disorders
0.700 0.300 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.700 0.300 0.000
R40 Somnolence, stupor and coma
0.700 0.300 0.000
C17.2 Ileum
0.699 0.301 0.000
I47.1 Supraventricular tachycardia
0.699 0.301 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.699 0.301 0.000
H61 Other disorders of external ear
0.698 0.302 0.000
H34 Retinal vascular occlusions
0.697 0.303 0.000
I69 Sequelae of cerebrovascular disease
0.697 0.303 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.697 0.303 0.000
G41 Status epilepticus
0.697 0.303 0.000
I37 Pulmonary valve disorders
0.697 0.303 0.000
F25 Schizoaffective disorders
0.697 0.303 0.000
J33 Nasal polyp
0.695 0.304 0.000
C15.5 Lower third of oesophagus
0.695 0.305 0.000
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified
0.694 0.306 0.000
J18 Pneumonia, organism unspecified
0.694 0.306 0.000
R02 Gangrene, not elsewhere classified
0.694 0.306 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.694 0.306 0.000
C18.8 Overlapping lesion of colon
0.694 0.306 0.000
C18.3 Hepatic flexure
0.694 0.306 0.000
C18.1 Appendix
0.694 0.306 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.693 0.307 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.693 0.307 0.000
T93.8 Sequelae of other specified injuries of lower limb
0.692 0.308 0.000
J60-J70 Lung diseases due to external agents
0.692 0.308 0.000
I42 Cardiomyopathy
0.692 0.308 0.000
V20-V29 Motorcycle rider injured in transport accident
0.691 0.309 0.000
T33-T35 Frostbite
0.691 0.309 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.691 0.309 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.691 0.309 0.000
T00-T07 Injuries involving multiple body regions
0.691 0.309 0.000
J38.1 Polyp of vocal cord and larynx
0.690 0.310 0.000
C34 Malignant neoplasm of bronchus and lung
0.690 0.310 0.000
R47.0 Dysphasia and aphasia
0.690 0.310 0.000
R46 Symptoms and signs involving appearance and behaviour
0.687 0.313 0.000
R43 Disturbances of smell and taste
0.687 0.313 0.000
C22.0 Liver cell carcinoma
0.687 0.313 0.000
H27 Other disorders of lens
0.687 0.313 0.000
D12.6 Colon, unspecified
0.687 0.313 0.000
O47.9 False labour, unspecified
0.687 0.313 0.000
I33 Acute and subacute endocarditis
0.686 0.314 0.000
F60-F69 Disorders of adult personality and behaviour
0.686 0.314 0.000
C25 Malignant neoplasm of pancreas
0.685 0.315 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.685 0.315 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.685 0.315 0.000
D26.1 Corpus uteri
0.685 0.315 0.000
H71 Cholesteatoma of middle ear
0.685 0.315 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.684 0.315 0.000
H35.7 Separation of retinal layers
0.684 0.316 0.000
H35.6 Retinal haemorrhage
0.684 0.316 0.000
H35.2 Other proliferative retinopathy
0.684 0.316 0.000
H35.1 Retinopathy of prematurity
0.684 0.316 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.683 0.317 0.000
G25 Other extrapyramidal and movement disorders
0.683 0.317 0.000
R09.2 Respiratory arrest
0.682 0.318 0.000
D75 Other diseases of blood and blood-forming organs
0.682 0.318 0.000
T93.3 Sequelae of dislocation, sprain and strain of lower limb
0.682 0.318 0.000
W18 Other fall on same level
0.681 0.319 0.000
W17 Other fall from one level to another
0.681 0.319 0.000
W16 Diving or jumping into water causing injury other than drowning or submersion
0.681 0.319 0.000
W15 Fall from cliff
0.681 0.319 0.000
W14 Fall from tree
0.681 0.319 0.000
W12 Fall on and from scaffolding
0.681 0.319 0.000
W11 Fall on and from ladder
0.681 0.319 0.000
W09 Fall involving playground equipment
0.681 0.319 0.000
W08 Fall involving other furniture
0.681 0.319 0.000
W05 Fall involving wheelchair
0.681 0.319 0.000
W04 Fall while being carried or supported by other persons
0.681 0.319 0.000
W03 Other fall on same level due to collision with, or pushing by, another person
0.681 0.319 0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards
0.681 0.319 0.000
W01 Fall on same level from slipping, tripping and stumbling
0.681 0.319 0.000
W00 Fall on same level involving ice and snow
0.681 0.319 0.000
I67.9 Cerebrovascular disease, unspecified
0.680 0.320 0.000
O40 Polyhydramnios
0.680 0.320 0.000
C18.7 Sigmoid colon
0.680 0.320 0.000
I49.3 Ventricular premature depolarisation
0.679 0.321 0.000
J03 Acute tonsillitis
0.679 0.321 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.678 0.322 0.000
J02 Acute pharyngitis
0.678 0.322 0.000
D32 Benign neoplasm of meninges
0.678 0.322 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.678 0.322 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.677 0.323 0.000
C15.4 Middle third of oesophagus
0.677 0.323 0.000
J05 Acute obstructive laryngitis [croup] and epiglottitis
0.676 0.323 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.675 0.325 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.673 0.327 0.000
T95 Sequelae of burns, corrosions and frostbite
0.672 0.327 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.672 0.327 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.672 0.327 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.672 0.327 0.000
O70 Perineal laceration during delivery
0.673 0.327 0.000
H33.4 Traction detachment of retina
0.672 0.328 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.671 0.329 0.000
F70-F79 Mental retardation
0.671 0.329 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.671 0.329 0.000
S52 Fracture of forearm
0.671 0.329 0.000
G45.8 Other transient cerebral ischaemic attacks and related syndromes
0.671 0.329 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.670 0.330 0.000
H44 Disorders of globe
0.668 0.332 0.000
W25 Contact with sharp glass
0.668 0.332 0.000
G43.8 Other migraine
0.668 0.332 0.000
G43.3 Complicated migraine
0.668 0.332 0.000
G43.2 Status migrainosus
0.668 0.332 0.000
G43.0 Migraine without aura [common migraine]
0.668 0.332 0.000
S92 Fracture of foot, except ankle
0.668 0.332 0.000
D13 Benign neoplasm of other and ill-defined parts of digestive system
0.667 0.333 0.000
C17.0 Duodenum
0.665 0.334 0.000
G40 Epilepsy
0.664 0.335 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.664 0.336 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.663 0.337 0.000
H49 Paralytic strabismus
0.663 0.337 0.000
T18 Foreign body in alimentary tract
0.663 0.337 0.000
O45 Premature separation of placenta [abruptio placentae]
0.662 0.337 0.000
O44 Placenta praevia
0.662 0.337 0.000
O43 Placental disorders
0.662 0.337 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.662 0.337 0.000
O33 Maternal care for known or suspected disproportion
0.662 0.337 0.000
O31 Complications specific to multiple gestation
0.662 0.337 0.000
O62 Abnormalities of forces of labour
0.662 0.338 0.000
I49.8 Other specified cardiac arrhythmias
0.661 0.339 0.000
O74 Complications of anaesthesia during labour and delivery
0.661 0.339 0.000
O73 Retained placenta and membranes, without haemorrhage
0.661 0.339 0.000
O71 Other obstetric trauma
0.661 0.339 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.661 0.339 0.000
O60 Preterm delivery
0.661 0.339 0.000
H28 Cataract and other disorders of lens in diseases classified elsewhere
0.660 0.340 0.000
I49.5 Sick sinus syndrome
0.659 0.341 0.000
D35 Benign neoplasm of other and unspecified endocrine glands
0.659 0.341 0.000
H90-H95 Other disorders of ear
0.658 0.342 0.000
I05-I09 Chronic rheumatic heart diseases
0.658 0.342 0.000
J06 Acute upper respiratory infections of multiple and unspecified sites
0.657 0.343 0.000
W19.8 Other specified place
0.656 0.344 0.000
W19.5 Trade and service area
0.656 0.344 0.000
W19.0 Home
0.656 0.344 0.000
W19.7 Farm
0.656 0.344 0.000
W19.6 Industrial and construction area
0.656 0.344 0.000
J38.4 Oedema of larynx
0.656 0.344 0.000
I45 Other conduction disorders
0.656 0.344 0.000
S32 Fracture of lumbar spine and pelvis
0.655 0.345 0.000
F23 Acute and transient psychotic disorders
0.655 0.345 0.000
F28 Other nonorganic psychotic disorders
0.655 0.345 0.000
F24 Induced delusional disorder
0.655 0.345 0.000
F21 Schizotypal disorder
0.655 0.345 0.000
O61 Failed induction of labour
0.655 0.345 0.000
I51.0 Cardiac septal defect, acquired
0.654 0.346 0.000
Y91 Evidence of alcohol involvement determined by level of intoxication
0.654 0.346 0.000
Y90 Evidence of alcohol involvement determined by blood alcohol level
0.654 0.346 0.000
Y98 Lifestyle-related condition
0.654 0.346 0.000
Y97 Environmental-pollution-related condition
0.654 0.346 0.000
Y96 Work-related condition
0.654 0.346 0.000
H61.2 Impacted cerumen
0.654 0.346 0.000
D36.7 Other specified sites
0.653 0.347 0.000
O66 Other obstructed labour
0.651 0.349 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.651 0.349 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.650 0.350 0.000
G45.3 Amaurosis fugax
0.650 0.350 0.000
G45.2 Multiple and bilateral precerebral artery syndromes
0.650 0.350 0.000
G45.1 Carotid artery syndrome (hemispheric)
0.650 0.350 0.000
G45.0 Vertebro-basilar artery syndrome
0.650 0.350 0.000
O04 Medical abortion
0.650 0.350 0.000
D75.1 Secondary polycythaemia
0.650 0.350 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.650 0.350 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.649 0.351 0.000
I34 Nonrheumatic mitral valve disorders
0.648 0.352 0.000
R47.8 Other and unspecified speech disturbances
0.648 0.352 0.000
W10 Fall on and from stairs and steps
0.648 0.352 0.000
Y43 Primarily systemic agents
0.648 0.352 0.000
J00 Acute nasopharyngitis [common cold]
0.647 0.353 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.647 0.353 0.000
O36.0 Maternal care for rhesus isoimmunisation
0.646 0.354 0.000
S19 Other and unspecified injuries of neck
0.645 0.355 0.000
O20 Haemorrhage in early pregnancy
0.645 0.355 0.000
S20-S29 Injuries to the thorax
0.645 0.355 0.000
O72.3 Postpartum coagulation defects
0.644 0.355 0.000
H17 Corneal scars and opacities
0.644 0.356 0.000
F22 Persistent delusional disorders
0.644 0.356 0.000
D14.0 Middle ear, nasal cavity and accessory sinuses
0.644 0.356 0.000
I31 Other diseases of pericardium
0.643 0.357 0.000
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.643 0.357 0.000
O97 Death from sequelae of direct obstetric causes
0.643 0.357 0.000
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery
0.643 0.357 0.000
O95 Obstetric death of unspecified cause
0.643 0.357 0.000
O94 Sequelae of complication of pregnancy, childbirth and the puerperium
0.643 0.357 0.000
D21.0 Connective and other soft tissue of head, face and neck
0.643 0.357 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.643 0.357 0.000
Y59 Other and unspecified vaccines and biological substances
0.642 0.357 0.000
Y58 Bacterial vaccines
0.642 0.357 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.642 0.357 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.642 0.357 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.642 0.357 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.642 0.357 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.642 0.357 0.000
Y48 Anaesthetics and therapeutic gases
0.642 0.357 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.642 0.357 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.642 0.357 0.000
V18 Pedal cyclist injured in noncollision transport accident
0.642 0.358 0.000
T79-T79 Certain early complications of trauma
0.642 0.358 0.000
I00-I02 Acute rheumatic fever
0.641 0.359 0.000
C34.3 Lower lobe, bronchus or lung
0.640 0.360 0.000
J92 Pleural plaque
0.640 0.360 0.000
I51.9 Heart disease, unspecified
0.639 0.361 0.000
W13 Fall from, out of or through building or structure
0.639 0.361 0.000
J20-J22 Other acute lower respiratory infections
0.639 0.361 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.639 0.361 0.000
H43.3 Other vitreous opacities
0.639 0.361 0.000
J33.9 Nasal polyp, unspecified
0.639 0.361 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.638 0.361 0.000
G90-G99 Other disorders of the nervous system
0.638 0.362 0.000
F20.8 Other schizophrenia
0.638 0.362 0.000
F20.6 Simple schizophrenia
0.638 0.362 0.000
F20.5 Residual schizophrenia
0.638 0.362 0.000
F20.4 Postschizophrenic depression
0.638 0.362 0.000
F20.3 Undifferentiated schizophrenia
0.638 0.362 0.000
F20.2 Catatonic schizophrenia
0.638 0.362 0.000
F20.1 Hebephrenic schizophrenia
0.638 0.362 0.000
G44.8 Other specified headache syndromes
0.637 0.363 0.000
G44.4 Drug-induced headache, not elsewhere classified
0.637 0.363 0.000
G44.3 Chronic posttraumatic headache
0.637 0.363 0.000
G44.1 Vascular headache, not elsewhere classified
0.637 0.363 0.000
G44.0 Cluster headache syndrome
0.637 0.363 0.000
C18.5 Splenic flexure
0.636 0.364 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.635 0.365 0.000
H20 Iridocyclitis
0.635 0.365 0.000
I35 Nonrheumatic aortic valve disorders
0.634 0.366 0.000
S50 Superficial injury of forearm
0.632 0.368 0.000
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified
0.632 0.368 0.000
H33.5 Other retinal detachments
0.632 0.368 0.000
T93.9 Sequelae of unspecified injury of lower limb
0.631 0.369 0.000
T93.6 Sequelae of crushing injury and traumatic amputation of lower limb
0.631 0.369 0.000
T93.5 Sequelae of injury of muscle and tendon of lower limb
0.631 0.369 0.000
T93.4 Sequelae of injury of nerve of lower limb
0.631 0.369 0.000
T93.0 Sequelae of open wound of lower limb
0.631 0.369 0.000
R81 Glycosuria
0.629 0.371 0.000
H36 Retinal disorders in diseases classified elsewhere
0.629 0.371 0.000
W29 Contact with other powered hand tools and household machinery
0.628 0.371 0.000
O99.3 Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium
0.628 0.372 0.000
R49 Voice disturbances
0.628 0.372 0.000
D33 Benign neoplasm of brain and other parts of central nervous system
0.628 0.372 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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