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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs115741020
log Bayes Factor = 14.7822
Chromosome 4   position 46,236,160  (GRCh37) Explore rs115741020 on Ensembl!
Variant rs115741020 is part of Cluster X0082

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
M05-M14 Inflammatory polyarthropathies
1.000 0.000 0.000
Chapter XIV Diseases of the genitourinary system
1.000 0.000 0.000
Chapter XX External causes of morbidity and mortality
0.999 0.001 0.000
Chapter II Neoplasms
0.997 0.003 0.000
Chapter VII Diseases of the eye and adnexa
0.996 0.004 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.996 0.004 0.000
M06 Other rheumatoid arthritis
0.996 0.004 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.995 0.005 0.000
M20-M25 Other joint disorders
0.993 0.007 0.000
M06.9 Rheumatoid arthritis, unspecified
0.992 0.008 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.992 0.008 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.992 0.008 0.000
Y83.2 Surgical operation with anastomosis, bypass or graft
0.983 0.017 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.981 0.019 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.979 0.021 0.000
C34 Malignant neoplasm of bronchus and lung
0.969 0.031 0.000
M13 Other arthritis
0.969 0.031 0.000
M25 Other joint disorders, not elsewhere classified
0.968 0.032 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.965 0.035 0.000
C79 Secondary malignant neoplasm of other sites
0.961 0.039 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.948 0.052 0.000
M13.9 Arthritis, unspecified
0.947 0.053 0.000
M25.5 Pain in joint
0.946 0.054 0.000
C34.1 Upper lobe, bronchus or lung
0.946 0.054 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.945 0.055 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.943 0.057 0.000
Chapter I Certain infectious and parasitic diseases
0.941 0.059 0.000
N17-N19 Renal failure
0.937 0.063 0.000
Y83.8 Other surgical procedures
0.937 0.063 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.931 0.069 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.927 0.073 0.000
M13.99 Arthritis, unspecified (Site unspecified)
0.925 0.075 0.000
N40-N51 Diseases of male genital organs
0.923 0.077 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.922 0.078 0.000
S60-S69 Injuries to the wrist and hand
0.919 0.081 0.000
N00-N08 Glomerular diseases
0.918 0.082 0.000
B25-B34 Other viral diseases
0.911 0.089 0.000
Chapter XXI Factors influencing health status and contact with health services
0.910 0.090 0.000
N18 Chronic renal failure
0.906 0.094 0.000
N40 Hyperplasia of prostate
0.903 0.097 0.000
M45-M49 Spondylopathies
0.903 0.097 0.000
M25.56 Pain in joint (Lower leg)
0.895 0.105 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.895 0.105 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.894 0.106 0.000
M23 Internal derangement of knee
0.891 0.109 0.000
M25.51 Pain in joint (Shoulder region)
0.890 0.110 0.000
M20 Acquired deformities of fingers and toes
0.890 0.110 0.000
B34 Viral infection of unspecified site
0.890 0.110 0.000
S70-S79 Injuries to the hip and thigh
0.890 0.110 0.000
N10-N16 Renal tubulo-interstitial diseases
0.889 0.111 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.889 0.111 0.000
N99-N99 Other disorders of the genitourinary system
0.888 0.112 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.886 0.114 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.884 0.116 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.884 0.116 0.000
B34.9 Viral infection, unspecified
0.875 0.125 0.000
M65-M68 Disorders of synovium and tendon
0.869 0.131 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.866 0.134 0.000
C77.1 Intrathoracic lymph nodes
0.863 0.137 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.863 0.137 0.000
H40-H42 Glaucoma
0.863 0.137 0.000
Y83.3 Surgical operation with formation of external stoma
0.861 0.139 0.000
C78.7 Secondary malignant neoplasm of liver
0.857 0.143 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.856 0.144 0.000
T39.1 4-Aminophenol derivatives
0.856 0.144 0.000
N25-N29 Other disorders of kidney and ureter
0.853 0.147 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.853 0.147 0.000
Z88.0 Personal history of allergy to penicillin
0.850 0.150 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.849 0.151 0.000
N18.5 Chronic kidney disease, stage 5
0.848 0.152 0.000
T66-T78 Other and unspecified effects of external causes
0.845 0.155 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.843 0.157 0.000
M05 Seropositive rheumatoid arthritis
0.843 0.157 0.000
Z88.6 Personal history of allergy to analgesic agent
0.841 0.159 0.000
B95-B98 Bacterial, viral and other infectious agents
0.838 0.162 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.836 0.164 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.835 0.165 0.000
S61 Open wound of wrist and hand
0.834 0.165 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.833 0.167 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.829 0.171 0.000
H01 Other inflammation of eyelid
0.829 0.171 0.000
M91-M94 Chondropathies
0.826 0.174 0.000
Z88.1 Personal history of allergy to other antibiotic agents
0.823 0.177 0.000
N60-N64 Disorders of breast
0.823 0.177 0.000
Chapter VIII Diseases of the ear and mastoid process
0.821 0.179 0.000
M10 Gout
0.819 0.181 0.000
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)
0.816 0.184 0.000
N18.9 Chronic renal failure, unspecified
0.816 0.184 0.000
M86-M90 Other osteopathies
0.815 0.185 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.814 0.186 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.814 0.186 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.814 0.186 0.000
C34.9 Bronchus or lung, unspecified
0.811 0.189 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.811 0.189 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.809 0.191 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.809 0.191 0.000
Y86 Sequelae of other accidents
0.809 0.191 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.809 0.191 0.000
H00 Hordeolum and chalazion
0.809 0.191 0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified
0.808 0.192 0.000
C34.3 Lower lobe, bronchus or lung
0.808 0.192 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.806 0.193 0.000
S72 Fracture of femur
0.806 0.194 0.000
N02 Recurrent and persistent haematuria
0.806 0.194 0.000
C80 Malignant neoplasm without specification of site
0.806 0.194 0.000
S20-S29 Injuries to the thorax
0.806 0.194 0.000
C78.0 Secondary malignant neoplasm of lung
0.804 0.196 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.802 0.197 0.000
T81 Complications of procedures, not elsewhere classified
0.802 0.198 0.000
M65 Synovitis and tenosynovitis
0.799 0.201 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.798 0.202 0.000
N20-N23 Urolithiasis
0.798 0.202 0.000
H55-H59 Other disorders of eye and adnexa
0.797 0.203 0.000
C77.8 Lymph nodes of multiple regions
0.797 0.203 0.000
M20.5 Other deformities of toe(s) (acquired)
0.796 0.204 0.000
H30-H36 Disorders of choroid and retina
0.795 0.205 0.000
H52 Disorders of refraction and accommodation
0.794 0.206 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.792 0.208 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.791 0.209 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.787 0.213 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.786 0.214 0.000
T93 Sequelae of injuries of lower limb
0.785 0.215 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.784 0.216 0.000
Y83.9 Surgical procedure, unspecified
0.781 0.218 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.779 0.221 0.000
Z91.0 Personal history of allergy, other than to drugs and biological substances
0.779 0.221 0.000
H02 Other disorders of eyelid
0.776 0.224 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.776 0.224 0.000
M13.95 Arthritis, unspecified (Pelvic region and thigh)
0.775 0.225 0.000
M47 Spondylosis
0.774 0.226 0.000
Z89 Acquired absence of limb
0.772 0.228 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.771 0.229 0.000
M06.0 Seronegative rheumatoid arthritis
0.771 0.229 0.000
M48 Other spondylopathies
0.769 0.231 0.000
T82.4 Mechanical complication of vascular dialysis catheter
0.768 0.232 0.000
H40 Glaucoma
0.767 0.233 0.000
N60 Benign mammary dysplasia
0.767 0.233 0.000
N18.0 End-stage renal disease
0.761 0.239 0.000
X60-X84 Intentional self-harm
0.759 0.241 0.000
M25.50 Pain in joint (Multiple sites)
0.756 0.244 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.756 0.244 0.000
C77.0 Lymph nodes of head, face and neck
0.755 0.245 0.000
Y95 Nosocomial condition
0.754 0.246 0.000
S61.0 Open wound of finger(s) without damage to nail
0.754 0.246 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.753 0.246 0.000
W00-W19 Falls
0.753 0.247 0.000
H43-H45 Disorders of vitreous body and globe
0.752 0.248 0.000
N76 Other inflammation of vagina and vulva
0.751 0.249 0.000
Y83.0 Surgical operation with transplant of whole organ
0.751 0.249 0.000
M34 Systemic sclerosis
0.751 0.249 0.000
N28 Other disorders of kidney and ureter, not elsewhere classified
0.749 0.251 0.000
S00-S09 Injuries to the head
0.748 0.252 0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts
0.747 0.253 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.746 0.254 0.000
H01.0 Blepharitis
0.746 0.254 0.000
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)
0.746 0.254 0.000
M13.96 Arthritis, unspecified (Lower leg)
0.746 0.254 0.000
M80-M85 Disorders of bone density and structure
0.746 0.254 0.000
N99.3 Prolapse of vaginal vault after hysterectomy
0.744 0.256 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.743 0.256 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.742 0.258 0.000
W20-W49 Exposure to inanimate mechanical forces
0.742 0.258 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.740 0.260 0.000
E10-E14 Diabetes mellitus
0.740 0.260 0.000
Chapter XXII Codes for special purposes
0.739 0.260 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.739 0.261 0.000
H10-H13 Disorders of conjunctiva
0.739 0.261 0.000
S90-S99 Injuries to the ankle and foot
0.738 0.262 0.000
T79-T79 Certain early complications of trauma
0.737 0.263 0.000
T78 Adverse effects, not elsewhere classified
0.734 0.266 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.733 0.267 0.000
N72 Inflammatory disease of cervix uteri
0.732 0.268 0.000
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.731 0.268 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.730 0.270 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.728 0.272 0.000
N05 Unspecified nephritic syndrome
0.728 0.272 0.000
M11 Other crystal arthropathies
0.726 0.274 0.000
N02.9 Unspecified
0.726 0.274 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.724 0.276 0.000
T39.0 Salicylates
0.724 0.276 0.000
T45.0 Antiallergic and antiemetic drugs
0.723 0.276 0.000
H53-H54 Visual disturbances and blindness
0.723 0.276 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.722 0.278 0.000
N60.1 Diffuse cystic mastopathy
0.722 0.278 0.000
N43 Hydrocele and spermatocele
0.722 0.278 0.000
M25.8 Other specified joint disorders
0.721 0.279 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.719 0.281 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.718 0.282 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.718 0.282 0.000
T90 Sequelae of injuries of head
0.718 0.282 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S10-S19 Injuries to the neck
0.717 0.283 0.000
M14 Arthropathies in other diseases classified elsewhere
0.717 0.283 0.000
M12 Other specific arthropathies
0.717 0.283 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.717 0.283 0.000
M08 Juvenile arthritis
0.717 0.283 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.717 0.283 0.000
Y35-Y36 Legal intervention and operations of war
0.717 0.283 0.000
Y10-Y34 Event of undetermined intent
0.717 0.283 0.000
Y00-Y09 Assault
0.717 0.283 0.000
X85-X99 Assault
0.717 0.283 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.717 0.283 0.000
X50-X57 Overexertion, travel and privation
0.717 0.283 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.717 0.283 0.000
X30-X39 Exposure to forces of nature
0.717 0.283 0.000
X20-X29 Contact with venomous animals and plants
0.717 0.283 0.000
X10-X19 Contact with heat and hot substances
0.717 0.283 0.000
X00-X09 Exposure to smoke, fire and flames
0.717 0.283 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.717 0.283 0.000
W75-W84 Other accidental threats to breathing
0.717 0.283 0.000
W65-W74 Accidental drowning and submersion
0.717 0.283 0.000
W50-W64 Exposure to animate mechanical forces
0.717 0.283 0.000
V98-V99 Other and unspecified transport accidents
0.717 0.283 0.000
V95-V97 Air and space transport accidents
0.717 0.283 0.000
V90-V94 Water transport accidents
0.717 0.283 0.000
V80-V89 Other land transport accidents
0.717 0.283 0.000
V70-V79 Bus occupant injured in transport accident
0.717 0.283 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.717 0.283 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.717 0.283 0.000
V40-V49 Car occupant injured in transport accident
0.717 0.283 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.717 0.283 0.000
V20-V29 Motorcycle rider injured in transport accident
0.717 0.283 0.000
V01-V09 Pedestrian injured in transport accident
0.717 0.283 0.000
T81.4 Infection following a procedure, not elsewhere classified
0.717 0.283 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.716 0.284 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.715 0.284 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.715 0.285 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.715 0.285 0.000
S62 Fracture at wrist and hand level
0.715 0.285 0.000
N23 Unspecified renal colic
0.715 0.285 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.714 0.286 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.714 0.286 0.000
M06.8 Other specified rheumatoid arthritis
0.714 0.286 0.000
M06.4 Inflammatory polyarthropathy
0.714 0.286 0.000
M06.3 Rheumatoid nodule
0.714 0.286 0.000
M06.2 Rheumatoid bursitis
0.714 0.286 0.000
M06.1 Adult-onset Still's disease
0.714 0.286 0.000
N10 Acute tubulo-interstitial nephritis
0.714 0.286 0.000
D10-D36 Benign neoplasms
0.712 0.288 0.000
H52.1 Myopia
0.712 0.288 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.712 0.288 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.712 0.288 0.000
M33 Dermatopolymyositis
0.712 0.288 0.000
M32 Systemic lupus erythematosus
0.712 0.288 0.000
M30 Polyarteritis nodosa and related conditions
0.712 0.288 0.000
M21 Other acquired deformities of limbs
0.712 0.288 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.711 0.288 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.711 0.288 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.711 0.288 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.711 0.288 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.711 0.288 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.711 0.289 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.711 0.289 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.711 0.289 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.711 0.289 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.711 0.289 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.711 0.289 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.711 0.289 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.711 0.289 0.000
T36 Poisoning by systemic antibiotics
0.711 0.289 0.000
Y83.5 Amputation of limb(s)
0.711 0.289 0.000
Chapter VI Diseases of the nervous system
0.708 0.292 0.000
N71 Inflammatory disease of uterus, except cervix
0.708 0.292 0.000
M25.7 Osteophyte
0.708 0.292 0.000
T93.3 Sequelae of dislocation, sprain and strain of lower limb
0.707 0.293 0.000
Z72 Problems related to lifestyle
0.707 0.293 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.707 0.293 0.000
N03 Chronic nephritic syndrome
0.706 0.294 0.000
H00.1 Chalazion
0.706 0.294 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.706 0.294 0.000
C77.9 Lymph node, unspecified
0.703 0.296 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.703 0.297 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.703 0.297 0.000
C32 Malignant neoplasm of larynx
0.703 0.297 0.000
C31 Malignant neoplasm of accessory sinuses
0.703 0.297 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.703 0.297 0.000
C37 Malignant neoplasm of thymus
0.703 0.297 0.000
C33 Malignant neoplasm of trachea
0.703 0.297 0.000
N50 Other disorders of male genital organs
0.703 0.297 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.702 0.298 0.000
T87 Complications peculiar to reattachment and amputation
0.702 0.298 0.000
T86 Failure and rejection of transplanted organs and tissues
0.702 0.298 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.702 0.298 0.000
M93 Other osteochondropathies
0.701 0.299 0.000
M13.94 Arthritis, unspecified (Hand)
0.699 0.301 0.000
M13.98 Arthritis, unspecified (Other)
0.699 0.301 0.000
Z94 Transplanted organ and tissue status
0.698 0.301 0.000
M25.57 Pain in joint (Ankle and foot)
0.697 0.303 0.000
Z88.3 Personal history of allergy to other anti-infective agents
0.697 0.303 0.000
Z98 Other postsurgical states
0.697 0.303 0.000
H25-H28 Disorders of lens
0.697 0.303 0.000
S67 Crushing injury of wrist and hand
0.696 0.304 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.696 0.304 0.000
M07 Psoriatic and enteropathic arthropathies
0.695 0.304 0.000
C34.8 Overlapping lesion of bronchus and lung
0.695 0.305 0.000
C34.2 Middle lobe, bronchus or lung
0.695 0.305 0.000
C34.0 Main bronchus
0.695 0.305 0.000
M13.8 Other specified arthritis
0.695 0.305 0.000
M13.1 Monoarthritis, not elsewhere classified
0.695 0.305 0.000
M13.0 Polyarthritis, unspecified
0.695 0.305 0.000
M25.9 Joint disorder, unspecified
0.694 0.306 0.000
M25.3 Other instability of joint
0.694 0.306 0.000
M25.2 Flail joint
0.694 0.306 0.000
M25.1 Fistula of joint
0.694 0.306 0.000
M25.0 Haemarthrosis
0.694 0.306 0.000
N45 Orchitis and epididymitis
0.693 0.307 0.000
E20-E35 Disorders of other endocrine glands
0.693 0.307 0.000
Y83.4 Other reconstructive surgery
0.693 0.307 0.000
Z88.4 Personal history of allergy to anaesthetic agent
0.693 0.307 0.000
Z88.5 Personal history of allergy to narcotic agent
0.692 0.308 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.692 0.308 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.692 0.308 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.691 0.309 0.000
S72.1 Pertrochanteric fracture
0.690 0.310 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.689 0.310 0.000
M10.9 Gout, unspecified
0.690 0.310 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.689 0.311 0.000
C79.6 Secondary malignant neoplasm of ovary
0.689 0.311 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.689 0.311 0.000
C79.2 Secondary malignant neoplasm of skin
0.689 0.311 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.689 0.311 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.689 0.311 0.000
M40-M43 Deforming dorsopathies
0.688 0.312 0.000
H21 Other disorders of iris and ciliary body
0.686 0.314 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.683 0.317 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.682 0.318 0.000
M46 Other inflammatory spondylopathies
0.681 0.319 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.681 0.319 0.000
C77.5 Intrapelvic lymph nodes
0.680 0.320 0.000
M13.93 Arthritis, unspecified (Forearm)
0.679 0.321 0.000
M13.92 Arthritis, unspecified (Upper arm)
0.679 0.321 0.000
H04 Disorders of lachrymal system
0.679 0.321 0.000
M25.59 Pain in joint (Site unspecified)
0.678 0.321 0.000
M25.58 Pain in joint (Other)
0.678 0.321 0.000
M25.52 Pain in joint (Upper arm)
0.678 0.321 0.000
S61.1 Open wound of finger(s) with damage to nail
0.678 0.322 0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.678 0.322 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.677 0.323 0.000
H05 Disorders of orbit
0.677 0.323 0.000
H03 Disorders of eyelid in diseases classified elsewhere
0.677 0.323 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.676 0.324 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.676 0.324 0.000
T39.4 Antirheumatics, not elsewhere classified
0.676 0.324 0.000
T39.2 Pyrazolone derivatives
0.676 0.324 0.000
Y88 Sequelae of surgical and medical care as external cause
0.676 0.324 0.000
N13 Obstructive and reflux uropathy
0.676 0.324 0.000
B15-B19 Viral hepatitis
0.676 0.324 0.000
T43.2 Other and unspecified antidepressants
0.676 0.324 0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal
0.676 0.324 0.000
K52 Other non-infective gastro-enteritis and colitis
0.675 0.325 0.000
B99-B99 Other infectious diseases
0.675 0.325 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.675 0.325 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.675 0.325 0.000
B65-B83 Helminthiases
0.675 0.325 0.000
B50-B64 Protozoal diseases
0.675 0.325 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.675 0.325 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.675 0.325 0.000
A80-A89 Viral infections of the central nervous system
0.675 0.325 0.000
A75-A79 Rickettsioses
0.675 0.325 0.000
A70-A74 Other diseases caused by chlamydiae
0.675 0.325 0.000
A65-A69 Other spirochaetal diseases
0.675 0.325 0.000
A20-A28 Certain zoonotic bacterial diseases
0.675 0.325 0.000
A15-A19 Tuberculosis
0.675 0.325 0.000
M48.0 Spinal stenosis
0.674 0.326 0.000
T51 Toxic effect of alcohol
0.673 0.327 0.000
D00-D09 In situ neoplasms
0.672 0.328 0.000
Chapter XI Diseases of the digestive system
0.672 0.328 0.000
Z72.0 Tobacco use
0.672 0.328 0.000
H60-H62 Diseases of external ear
0.672 0.328 0.000
M20.2 Hallux rigidus
0.671 0.329 0.000
Z93 Artificial opening status
0.670 0.329 0.000
S40-S49 Injuries to the shoulder and upper arm
0.670 0.330 0.000
K52.9 Non-infective gastro-enteritis and colitis, unspecified
0.670 0.330 0.000
K50-K52 Noninfective enteritis and colitis
0.670 0.330 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.669 0.330 0.000
B97.7 Papillomavirus as the cause of diseases classified to other chapters
0.669 0.331 0.000
M35 Other systemic involvement of connective tissue
0.669 0.331 0.000
H02.0 Entropion and trichiasis of eyelid
0.668 0.332 0.000
N17 Acute renal failure
0.668 0.332 0.000
M31 Other necrotising vasculopathies
0.667 0.332 0.000
C77.4 Inguinal and lower limb lymph nodes
0.667 0.332 0.000
N73 Other female pelvic inflammatory diseases
0.667 0.333 0.000
H65-H75 Diseases of middle ear and mastoid
0.667 0.333 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.666 0.333 0.000
Z91.5 Personal history of self-harm
0.665 0.335 0.000
C01 Malignant neoplasm of base of tongue
0.665 0.335 0.000
M86 Osteomyelitis
0.664 0.336 0.000
N28.8 Other specified disorders of kidney and ureter
0.664 0.336 0.000
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)
0.664 0.336 0.000
M23.5 Chronic instability of knee
0.664 0.336 0.000
Z88.2 Personal history of allergy to sulphonamides
0.663 0.337 0.000
N51 Disorders of male genital organs in diseases classified elsewhere
0.662 0.338 0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.662 0.338 0.000
N46 Male infertility
0.662 0.338 0.000
N44 Torsion of testis
0.662 0.338 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.662 0.338 0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care
0.661 0.339 0.000
E10 Insulin-dependent diabetes mellitus
0.661 0.339 0.000
Z89.6 Acquired absence of leg above knee
0.661 0.339 0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft
0.661 0.339 0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis
0.661 0.339 0.000
T82.3 Mechanical complication of other vascular grafts
0.661 0.339 0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.661 0.339 0.000
T82.1 Mechanical complication of cardiac electronic device
0.661 0.339 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.661 0.339 0.000
S69 Other and unspecified injuries of wrist and hand
0.659 0.341 0.000
S65 Injury of blood vessels at wrist and hand level
0.659 0.341 0.000
S60 Superficial injury of wrist and hand
0.659 0.341 0.000
M24 Other specific joint derangements
0.659 0.341 0.000
G90-G99 Other disorders of the nervous system
0.659 0.341 0.000
N07 Hereditary nephropathy, not elsewhere classified
0.658 0.342 0.000
N06 Isolated proteinuria with specified morphological lesion
0.658 0.342 0.000
N04 Nephrotic syndrome
0.658 0.342 0.000
N01 Rapidly progressive nephritic syndrome
0.658 0.342 0.000
N00 Acute nephritic syndrome
0.658 0.342 0.000
C80.0 Malignant neoplasm, primary site unknown, so stated
0.657 0.343 0.000
S68 Traumatic amputation of wrist and hand
0.657 0.343 0.000
M20.3 Other deformity of hallux (acquired)
0.656 0.344 0.000
M22 Disorders of patella
0.656 0.344 0.000
H57 Other disorders of eye and adnexa
0.654 0.345 0.000
B33 Other viral diseases, not elsewhere classified
0.653 0.347 0.000
B30 Viral conjunctivitis
0.653 0.347 0.000
B27 Infectious mononucleosis
0.653 0.347 0.000
B26 Mumps
0.653 0.347 0.000
B25 Cytomegaloviral disease
0.653 0.347 0.000
M20.0 Deformity of finger(s)
0.652 0.348 0.000
S70 Superficial injury of hip and thigh
0.651 0.349 0.000
Z97 Presence of other devices
0.651 0.349 0.000
C48 Malignant neoplasm of retroperitoneum and peritoneum
0.651 0.349 0.000
M20.4 Other hammer toe(s) (acquired)
0.651 0.349 0.000
V10-V19 Pedal cyclist injured in transport accident
0.651 0.349 0.000
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.651 0.349 0.000
N18.2 Chronic kidney disease, stage 2
0.651 0.349 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.650 0.350 0.000
M25.4 Effusion of joint
0.649 0.351 0.000
N18.8 Other chronic renal failure
0.649 0.351 0.000
N18.1 Chronic kidney disease, stage 1
0.649 0.351 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.649 0.351 0.000
M47.9 Spondylosis, unspecified
0.647 0.353 0.000
M49 Spondylopathies in diseases classified elsewhere
0.647 0.353 0.000
T42.4 Benzodiazepines
0.644 0.356 0.000
S72.3 Fracture of shaft of femur
0.643 0.357 0.000
N62 Hypertrophy of breast
0.642 0.358 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.642 0.358 0.000
Y89 Sequelae of other external causes
0.642 0.358 0.000
Y87 Sequelae of intentional self-harm, assault and events of undetermined intent
0.642 0.358 0.000
Y85 Sequelae of transport accidents
0.642 0.358 0.000
S72.0 Fracture of neck of femur
0.642 0.358 0.000
T98 Sequelae of other and unspecified effects of external causes
0.641 0.359 0.000
T95 Sequelae of burns, corrosions and frostbite
0.641 0.359 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.641 0.359 0.000
T92 Sequelae of injuries of upper limb
0.641 0.359 0.000
T91 Sequelae of injuries of neck and trunk
0.641 0.359 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.641 0.359 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.641 0.359 0.000
K52.8 Other specified non-infective gastro-enteritis and colitis
0.641 0.359 0.000
H35 Other retinal disorders
0.640 0.360 0.000
H18 Other disorders of cornea
0.640 0.360 0.000
M13.97 Arthritis, unspecified (Ankle and foot)
0.639 0.361 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.639 0.361 0.000
S64 Injury of nerves at wrist and hand level
0.639 0.361 0.000
M23.9 Internal derangement of knee, unspecified
0.639 0.361 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.639 0.361 0.000
M23.4 Loose body in knee
0.639 0.361 0.000
M23.1 Discoid meniscus (congenital)
0.639 0.361 0.000
M23.0 Cystic meniscus
0.639 0.361 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.638 0.362 0.000
M20.6 Acquired deformity of toe(s), unspecified
0.638 0.362 0.000
B34.8 Other viral infections of unspecified site
0.638 0.362 0.000
B34.4 Papovirus infection, unspecified
0.638 0.362 0.000
B34.3 Parvovirus infection, unspecified
0.638 0.362 0.000
B34.2 Coronavirus infection, unspecified
0.638 0.362 0.000
B34.1 Enterovirus infection, unspecified
0.638 0.362 0.000
B34.0 Adenovirus infection, unspecified
0.638 0.362 0.000
S79 Other and unspecified injuries of hip and thigh
0.638 0.362 0.000
S78 Traumatic amputation of hip and thigh
0.638 0.362 0.000
S77 Crushing injury of hip and thigh
0.638 0.362 0.000
S76 Injury of muscle and tendon at hip and thigh level
0.638 0.362 0.000
S75 Injury of blood vessels at hip and thigh level
0.638 0.362 0.000
S74 Injury of nerves at hip and thigh level
0.638 0.362 0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip
0.638 0.362 0.000
S71 Open wound of hip and thigh
0.638 0.362 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.638 0.362 0.000
N15 Other renal tubulo-interstitial diseases
0.638 0.362 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.638 0.362 0.000
N11 Chronic tubulo-interstitial nephritis
0.638 0.362 0.000
N74 Female pelvic inflammatory disorders in diseases classified elsewhere
0.637 0.362 0.000
M25.54 Pain in joint (Hand)
0.637 0.363 0.000
Z88.9 Personal history of allergy to unspecified drugs, medicaments and biological substances
0.635 0.365 0.000
Z88.7 Personal history of allergy to serum and vaccine
0.635 0.365 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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