TreeWAS – Variant ID: rs11575907

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K90.0 Coeliac disease	0.000	0.000	1.000
L40.9 Psoriasis, unspecified	1.000	0.000	0.000
L40.5 Arthropathic psoriasis	1.000	0.000	0.000
L40 Psoriasis	1.000	0.000	0.000
J40-J47 Chronic lower respiratory diseases	0.000	0.000	1.000
J47 Bronchiectasis	0.000	0.000	1.000
T36-T50 Poisoning by drugs, medicaments and biological substances	1.000	0.000	0.000
Chapter X Diseases of the respiratory system	0.000	0.001	0.999
J30-J39 Other diseases of upper respiratory tract	0.000	0.001	0.999
J33 Nasal polyp	0.000	0.001	0.999
J33.9 Nasal polyp, unspecified	0.000	0.003	0.997
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.995	0.005	0.000
L40-L45 Papulosquamous disorders	0.995	0.005	0.000
# Top node	0.994	0.006	0.000
Chapter XII Diseases of the skin and subcutaneous tissue	0.992	0.008	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.992	0.008	0.000
J44 Other chronic obstructive pulmonary disease	0.000	0.008	0.992
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection	0.000	0.021	0.979
Chapter II Neoplasms	0.968	0.032	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.966	0.034	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.966	0.034	0.000
M05-M14 Inflammatory polyarthropathies	0.965	0.035	0.000
M07 Psoriatic and enteropathic arthropathies	0.964	0.036	0.000
M07.3 Other psoriatic arthropathies	0.964	0.036	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.962	0.038	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.961	0.039	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.957	0.043	0.000
J45 Asthma	0.000	0.043	0.957
M07.39 Other psoriatic arthropathies (Site unspecified)	0.954	0.046	0.000
J33.0 Polyp of nasal cavity	0.000	0.047	0.953
T42.4 Benzodiazepines	0.946	0.054	0.000
Chapter IX Diseases of the circulatory system	0.937	0.063	0.000
T43.2 Other and unspecified antidepressants	0.935	0.065	0.000
M07.30 Other psoriatic arthropathies (Multiple sites)	0.935	0.065	0.000
C15-C26 Malignant neoplasms of digestive organs	0.930	0.070	0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.920	0.080	0.000
T39.1 4-Aminophenol derivatives	0.918	0.082	0.000
J44.8 Other specified chronic obstructive pulmonary disease	0.000	0.085	0.915
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.912	0.088	0.000
J45.9 Asthma, unspecified	0.000	0.089	0.911
M13 Other arthritis	0.903	0.097	0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.895	0.105	0.000
J80-J84 Other respiratory diseases principally affecting the interstitium	0.000	0.106	0.894
I60-I69 Cerebrovascular diseases	0.893	0.107	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.892	0.108	0.000
Chapter V Mental and behavioural disorders	0.892	0.108	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.886	0.114	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.885	0.115	0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.882	0.118	0.000
L40.0 Psoriasis vulgaris	0.878	0.122	0.000
I20-I25 Ischaemic heart diseases	0.877	0.123	0.000
J33.8 Other polyp of sinus	0.000	0.133	0.867
Q80-Q89 Other congenital malformations	0.865	0.135	0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.864	0.136	0.000
I27 Other pulmonary heart diseases	0.863	0.137	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.862	0.138	0.000
J46 Status asthmaticus	0.000	0.140	0.860
T51 Toxic effect of alcohol	0.860	0.140	0.000
J60-J70 Lung diseases due to external agents	0.000	0.141	0.859
M13.9 Arthritis, unspecified	0.854	0.146	0.000
C21 Malignant neoplasm of anus and anal canal	0.854	0.146	0.000
D37-D48 Neoplasms of uncertain or unknown behaviour	0.849	0.151	0.000
C18 Malignant neoplasm of colon	0.848	0.152	0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified	0.841	0.159	0.000
I27.0 Primary pulmonary hypertension	0.836	0.164	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.834	0.166	0.000
F40-F48 Neurotic, stress-related and somatoform disorders	0.834	0.166	0.000
Chapter VI Diseases of the nervous system	0.833	0.167	0.000
C18.7 Sigmoid colon	0.828	0.172	0.000
S90-S99 Injuries to the ankle and foot	0.825	0.175	0.000
M65-M68 Disorders of synovium and tendon	0.825	0.175	0.000
J30 Vasomotor and allergic rhinitis	0.000	0.175	0.825
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.822	0.178	0.000
T51.0 Ethanol	0.821	0.179	0.000
I24 Other acute ischaemic heart diseases	0.821	0.179	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.815	0.185	0.000
Chapter XXII Codes for special purposes	0.815	0.185	0.000
M40-M43 Deforming dorsopathies	0.810	0.190	0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis	0.000	0.191	0.809
T46 Poisoning by agents primarily affecting the cardiovascular system	0.808	0.192	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.807	0.193	0.000
C25 Malignant neoplasm of pancreas	0.804	0.196	0.000
I67 Other cerebrovascular diseases	0.803	0.197	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.803	0.197	0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified	0.000	0.200	0.800
Q20-Q28 Congenital malformations of the circulatory system	0.791	0.209	0.000
F60-F69 Disorders of adult personality and behaviour	0.788	0.212	0.000
I25 Chronic ischaemic heart disease	0.782	0.218	0.000
J84 Other interstitial pulmonary diseases	0.000	0.218	0.781
M13.99 Arthritis, unspecified (Site unspecified)	0.781	0.219	0.000
M60-M63 Disorders of muscles	0.781	0.219	0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.779	0.221	0.000
I69 Sequelae of cerebrovascular disease	0.778	0.222	0.000
J45.0 Predominantly allergic asthma	0.000	0.228	0.772
C21.1 Anal canal	0.770	0.230	0.000
I24.9 Acute ischaemic heart disease, unspecified	0.770	0.230	0.000
I95-I99 Other and unspecified disorders of the circulatory system	0.768	0.232	0.000
Q50-Q56 Congenital malformations of genital organs	0.768	0.232	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.764	0.236	0.000
M86-M90 Other osteopathies	0.761	0.239	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.759	0.241	0.000
L50-L54 Urticaria and erythema	0.756	0.244	0.000
Q60-Q64 Congenital malformations of the urinary system	0.754	0.246	0.000
T39.0 Salicylates	0.754	0.246	0.000
M13.97 Arthritis, unspecified (Ankle and foot)	0.752	0.248	0.000
G40-G47 Episodic and paroxysmal disorders	0.752	0.248	0.000
C18.9 Colon, unspecified	0.752	0.248	0.000
T23 Burn and corrosion of wrist and hand	0.750	0.249	0.000
C32 Malignant neoplasm of larynx	0.750	0.250	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.749	0.251	0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.748	0.252	0.000
C82.0 Small cleaved cell, follicular	0.747	0.253	0.000
G20-G26 Extrapyramidal and movement disorders	0.745	0.255	0.000
Q83 Congenital malformations of breast	0.745	0.255	0.000
F41 Other anxiety disorders	0.744	0.256	0.000
J42 Unspecified chronic bronchitis	0.000	0.260	0.740
S20-S29 Injuries to the thorax	0.739	0.261	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.737	0.263	0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.737	0.263	0.000
J69 Pneumonitis due to solids and liquids	0.000	0.264	0.736
F45 Somatoform disorders	0.734	0.266	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.604	0.266	0.131
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.734	0.266	0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.732	0.268	0.000
M14 Arthropathies in other diseases classified elsewhere	0.732	0.268	0.000
C17 Malignant neoplasm of small intestine	0.731	0.268	0.000
G45 Transient cerebral ischaemic attacks and related syndromes	0.730	0.270	0.000
I60 Subarachnoid haemorrhage	0.729	0.271	0.000
J81 Pulmonary oedema	0.000	0.272	0.728
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.728	0.272	0.000
I64 Stroke, not specified as haemorrhage or infarction	0.727	0.273	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.726	0.274	0.000
G70-G73 Diseases of myoneural junction and muscle	0.726	0.274	0.000
F30-F39 Mood [affective] disorders	0.725	0.275	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.722	0.278	0.000
I27.2 Other secondary pulmonary hypertension	0.722	0.278	0.000
S10-S19 Injuries to the neck	0.721	0.279	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.720	0.280	0.000
L40.8 Other psoriasis	0.717	0.283	0.000
L40.4 Guttate psoriasis	0.717	0.283	0.000
L40.3 Pustulosis palmaris et plantaris	0.717	0.283	0.000
L40.2 Acrodermatitis continua	0.717	0.283	0.000
L40.1 Generalised pustular psoriasis	0.717	0.283	0.000
J41 Simple and mucopurulent chronic bronchitis	0.000	0.283	0.717
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.717	0.283	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.717	0.283	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.717	0.283	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.717	0.283	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.717	0.283	0.000
T36 Poisoning by systemic antibiotics	0.717	0.283	0.000
J37 Chronic laryngitis and laryngotracheitis	0.000	0.284	0.716
J33.1 Polypoid sinus degeneration	0.000	0.284	0.716
T33-T35 Frostbite	0.714	0.286	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.714	0.286	0.000
T00-T07 Injuries involving multiple body regions	0.714	0.286	0.000
L44 Other papulosquamous disorders	0.713	0.287	0.000
L41 Parapsoriasis	0.713	0.287	0.000
L45 Papulosquamous disorders in diseases classified elsewhere	0.713	0.287	0.000
L42 Pityriasis rosea	0.713	0.287	0.000
F60 Specific personality disorders	0.713	0.287	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.713	0.287	0.000
T79-T79 Certain early complications of trauma	0.712	0.287	0.000
I10-I15 Hypertensive diseases	0.712	0.288	0.000
C64-C68 Malignant neoplasms of urinary tract	0.712	0.288	0.000
C82.1 Mixed small cleaved and large cell, follicular	0.712	0.288	0.000
J32 Chronic sinusitis	0.000	0.288	0.712
L10-L14 Bullous disorders	0.712	0.288	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.711	0.288	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.711	0.288	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.711	0.288	0.000
T42.3 Barbiturates	0.711	0.288	0.000
T42.2 Succinimides and oxazolidinediones	0.711	0.288	0.000
T42.1 Iminostilbenes	0.711	0.288	0.000
T42.0 Hydantoin derivatives	0.711	0.288	0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.710	0.290	0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.708	0.292	0.000
I21 Acute myocardial infarction	0.707	0.293	0.000
L60-L75 Disorders of skin appendages	0.706	0.294	0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified	0.000	0.294	0.706
C34 Malignant neoplasm of bronchus and lung	0.705	0.295	0.000
E10-E14 Diabetes mellitus	0.581	0.295	0.124
F41.0 Panic disorder [episodic paroxysmal anxiety]	0.704	0.296	0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.000	0.297	0.703
C25.0 Head of pancreas	0.703	0.297	0.000
Q00-Q07 Congenital malformations of the nervous system	0.702	0.298	0.000
J35 Chronic diseases of tonsils and adenoids	0.000	0.299	0.700
D46 Myelodysplastic syndromes	0.700	0.300	0.000
M65 Synovitis and tenosynovitis	0.699	0.301	0.000
T20 Burn and corrosion of head and neck	0.699	0.301	0.000
J84.9 Interstitial pulmonary disease, unspecified	0.000	0.302	0.698
T43.3 Phenothiazine antipsychotics and neuroleptics	0.698	0.302	0.000
M11 Other crystal arthropathies	0.698	0.302	0.000
M00-M03 Infectious arthropathies	0.697	0.303	0.000
I25.1 Atherosclerotic heart disease	0.696	0.304	0.000
I21.4 Acute subendocardial myocardial infarction	0.696	0.304	0.000
C21.0 Anus, unspecified	0.696	0.304	0.000
Q21 Congenital malformations of cardiac septa	0.695	0.305	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.694	0.305	0.000
C40-C41 Malignant neoplasms of bone and articular cartilage	0.694	0.306	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.693	0.307	0.000
Q35-Q37 Cleft lip and cleft palate	0.693	0.307	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.693	0.307	0.000
M12 Other specific arthropathies	0.692	0.308	0.000
M09 Juvenile arthritis in diseases classified elsewhere	0.692	0.308	0.000
M08 Juvenile arthritis	0.692	0.308	0.000
T66-T78 Other and unspecified effects of external causes	0.692	0.308	0.000
M91-M94 Chondropathies	0.692	0.308	0.000
M07.6 Other enteropathic arthropathies	0.691	0.309	0.000
M07.5 Arthropathy in ulcerative colitis	0.691	0.309	0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]	0.691	0.309	0.000
M07.2 Psoriatic spondylitis	0.691	0.309	0.000
M07.1 Arthritis mutilans	0.691	0.309	0.000
M07.0 Distal interphalangeal psoriatic arthropathy	0.691	0.309	0.000
M07.38 Other psoriatic arthropathies (Other)	0.691	0.309	0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.691	0.309	0.000
M07.36 Other psoriatic arthropathies (Lower leg)	0.691	0.309	0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.691	0.309	0.000
M07.34 Other psoriatic arthropathies (Hand)	0.691	0.309	0.000
M07.33 Other psoriatic arthropathies (Forearm)	0.691	0.309	0.000
M07.32 Other psoriatic arthropathies (Upper arm)	0.691	0.309	0.000
M07.31 Other psoriatic arthropathies (Shoulder region)	0.691	0.309	0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.691	0.309	0.000
E00-E07 Disorders of thyroid gland	0.025	0.309	0.665
C82.7 Other types of follicular non-Hodgkin's lymphoma	0.690	0.310	0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.690	0.310	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.689	0.311	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.689	0.311	0.000
T39.4 Antirheumatics, not elsewhere classified	0.689	0.311	0.000
T39.2 Pyrazolone derivatives	0.689	0.311	0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.689	0.311	0.000
Q82 Other congenital malformations of skin	0.689	0.311	0.000
G45.9 Transient cerebral ischaemic attack, unspecified	0.688	0.312	0.000
C91 Lymphoid leukaemia	0.688	0.312	0.000
T43.9 Psychotropic drug, unspecified	0.686	0.314	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.686	0.314	0.000
T43.6 Psychostimulants with abuse potential	0.686	0.314	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.686	0.314	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.686	0.314	0.000
J45.8 Mixed asthma	0.000	0.314	0.686
J45.1 Nonallergic asthma	0.000	0.314	0.686
T92 Sequelae of injuries of upper limb	0.685	0.315	0.000
I95 Hypotension	0.685	0.315	0.000
J30.1 Allergic rhinitis due to pollen	0.000	0.320	0.680
J90-J94 Other diseases of pleura	0.000	0.320	0.680
E03 Other hypothyroidism	0.011	0.321	0.668
M13.95 Arthritis, unspecified (Pelvic region and thigh)	0.678	0.322	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.677	0.323	0.000
S92 Fracture of foot, except ankle	0.677	0.323	0.000
M13.96 Arthritis, unspecified (Lower leg)	0.676	0.324	0.000
C90 Multiple myeloma and malignant plasma cell neoplasms	0.676	0.324	0.000
E03.9 Hypothyroidism, unspecified	0.000	0.326	0.674
J31.0 Chronic rhinitis	0.000	0.326	0.674
I67.1 Cerebral aneurysm, nonruptured	0.673	0.327	0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.673	0.327	0.000
M13.0 Polyarthritis, unspecified	0.672	0.328	0.000
I00-I02 Acute rheumatic fever	0.672	0.328	0.000
I25.0 Atherosclerotic cardiovascular disease, so described	0.669	0.330	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.007	0.331	0.662
T91 Sequelae of injuries of neck and trunk	0.668	0.332	0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.667	0.333	0.000
C23 Malignant neoplasm of gallbladder	0.667	0.333	0.000
M41 Scoliosis	0.666	0.334	0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.666	0.334	0.000
F99-F99 Unspecified mental disorder	0.665	0.335	0.000
C26 Malignant neoplasm of other and ill-defined digestive organs	0.664	0.336	0.000
F45.8 Other somatoform disorders	0.663	0.337	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.663	0.337	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.662	0.338	0.000
I67.8 Other specified cerebrovascular diseases	0.660	0.340	0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.660	0.340	0.000
C95 Leukaemia of unspecified cell type	0.660	0.340	0.000
C94 Other leukaemias of specified cell type	0.660	0.340	0.000
C93 Monocytic leukaemia	0.660	0.340	0.000
C88 Malignant immunoproliferative diseases	0.660	0.340	0.000
C86 Other specified types of T/NK-cell lymphoma	0.660	0.340	0.000
C84 Peripheral and cutaneous T-cell lymphomas	0.660	0.340	0.000
C81 Hodgkin's disease	0.660	0.340	0.000
J61 Pneumoconiosis due to asbestos and other mineral fibres	0.000	0.340	0.660
S70-S79 Injuries to the hip and thigh	0.659	0.341	0.000
Q83.8 Other congenital malformations of breast	0.659	0.341	0.000
Q87 Other specified congenital malformation syndromes affecting multiple systems	0.659	0.341	0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.657	0.343	0.000
S40-S49 Injuries to the shoulder and upper arm	0.656	0.344	0.000
J95-J99 Other diseases of the respiratory system	0.000	0.344	0.656
T90 Sequelae of injuries of head	0.654	0.346	0.000
T65 Toxic effect of other and unspecified substances	0.654	0.346	0.000
T62 Toxic effect of other noxious substances eaten as food	0.654	0.346	0.000
T61 Toxic effect of noxious substances eaten as seafood	0.654	0.346	0.000
T60 Toxic effect of pesticides	0.654	0.346	0.000
T59 Toxic effect of other gases, fumes and vapours	0.654	0.346	0.000
T57 Toxic effect of other inorganic substances	0.654	0.346	0.000
T56 Toxic effect of metals	0.654	0.346	0.000
T54 Toxic effect of corrosive substances	0.654	0.346	0.000
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone	0.654	0.346	0.000
T52 Toxic effect of organic solvents	0.654	0.346	0.000
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants	0.654	0.346	0.000
T58 Toxic effect of carbon monoxide	0.654	0.346	0.000
T55 Toxic effect of soaps and detergents	0.654	0.346	0.000
T23.0 Burn of unspecified degree of wrist and hand	0.654	0.346	0.000
Q76 Congenital malformations of spine and bony thorax	0.653	0.347	0.000
I25.5 Ischaemic cardiomyopathy	0.651	0.349	0.000
C50-C50 Malignant neoplasm of breast	0.651	0.349	0.000
I67.2 Cerebral atherosclerosis	0.650	0.350	0.000
S99 Other and unspecified injuries of ankle and foot	0.649	0.351	0.000
J69.0 Pneumonitis due to food and vomit	0.000	0.352	0.648
I69.1 Sequelae of intracerebral haemorrhage	0.648	0.352	0.000
M13.8 Other specified arthritis	0.647	0.352	0.000
M13.1 Monoarthritis, not elsewhere classified	0.647	0.352	0.000
M62 Other disorders of muscle	0.648	0.352	0.000
G45.3 Amaurosis fugax	0.647	0.353	0.000
G90-G99 Other disorders of the nervous system	0.646	0.354	0.000
J38.4 Oedema of larynx	0.000	0.355	0.645
E05.9 Thyrotoxicosis, unspecified	0.001	0.356	0.643
M45-M49 Spondylopathies	0.644	0.356	0.000
C97 Malignant neoplasms of independent (primary) multiple sites	0.644	0.356	0.000
I27.9 Pulmonary heart disease, unspecified	0.642	0.358	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.642	0.358	0.000
C32.0 Glottis	0.642	0.358	0.000
C82.6 Cutaneous follicle centre lymphoma	0.642	0.358	0.000
C82.5 Diffuse follicle centre lymphoma	0.642	0.358	0.000
C82.4 Follicular lymphoma grade IIIb	0.642	0.358	0.000
C82.3 Follicular lymphoma grade IIIa	0.642	0.358	0.000
C82.2 Large cell, follicular	0.642	0.358	0.000
J82 Pulmonary eosinophilia, not elsewhere classified	0.000	0.359	0.641
I68 Cerebrovascular disorders in diseases classified elsewhere	0.640	0.360	0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.640	0.360	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.640	0.360	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.640	0.360	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.640	0.360	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.640	0.360	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.640	0.360	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.640	0.360	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.640	0.360	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.640	0.360	0.000
T44.0 Anticholinesterase agents	0.640	0.360	0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.640	0.360	0.000
F70-F79 Mental retardation	0.640	0.360	0.000
Q51 Congenital malformations of uterus and cervix	0.640	0.360	0.000
J34 Other disorders of nose and nasal sinuses	0.000	0.361	0.639
M13.90 Arthritis, unspecified (Multiple sites)	0.639	0.361	0.000
I61 Intracerebral haemorrhage	0.639	0.361	0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.638	0.361	0.000
C18.4 Transverse colon	0.638	0.362	0.000
M80-M85 Disorders of bone density and structure	0.637	0.363	0.000
J80 Adult respiratory distress syndrome	0.000	0.363	0.637
M67 Other disorders of synovium and tendon	0.636	0.364	0.000
T98 Sequelae of other and unspecified effects of external causes	0.636	0.364	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.002	0.364	0.634
T25 Burn and corrosion of ankle and foot	0.635	0.365	0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.635	0.365	0.000
T21 Burn and corrosion of trunk	0.635	0.365	0.000
C83 Diffuse non-Hodgkin's lymphoma	0.635	0.365	0.000
T50.8 Diagnostic agents	0.635	0.365	0.000
T50.7 Analeptics and opioid receptor antagonists	0.635	0.365	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.635	0.365	0.000
T50.5 Appetite depressants	0.635	0.365	0.000
T50.4 Drugs affecting uric acid metabolism	0.635	0.365	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.635	0.365	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.635	0.365	0.000
T50.1 Loop [high-ceiling] diuretics	0.635	0.365	0.000
T50.0 Mineralocorticoids and their antagonists	0.635	0.365	0.000
I95.9 Hypotension, unspecified	0.635	0.365	0.000
G20 Parkinson's disease	0.634	0.366	0.000
D00-D09 In situ neoplasms	0.633	0.367	0.000
I28 Other diseases of pulmonary vessels	0.633	0.367	0.000
J38.0 Paralysis of vocal cords and larynx	0.000	0.368	0.632
G40 Epilepsy	0.632	0.368	0.000
M43 Other deforming dorsopathies	0.630	0.369	0.000
J30.3 Other allergic rhinitis	0.000	0.369	0.630
I69.0 Sequelae of subarachnoid haemorrhage	0.630	0.370	0.000
I23 Certain current complications following acute myocardial infarction	0.628	0.371	0.000
M13.93 Arthritis, unspecified (Forearm)	0.628	0.372	0.000
F42 Obsessive-compulsive disorder	0.628	0.372	0.000
T51.9 Alcohol, unspecified	0.626	0.373	0.000
J40 Bronchitis, not specified as acute or chronic	0.000	0.375	0.625
M65.9 Synovitis and tenosynovitis, unspecified	0.625	0.375	0.000
M87 Osteonecrosis	0.623	0.377	0.000
S22 Fracture of rib(s), sternum and thoracic spine	0.623	0.377	0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.622	0.378	0.000
Q63 Other congenital malformations of kidney	0.621	0.379	0.000
L52 Erythema nodosum	0.620	0.380	0.000
Q89 Other congenital malformations, not elsewhere classified	0.620	0.380	0.000
Q86 Congenital malformation syndromes due to known exogenous causes, not elsewhere classified	0.620	0.380	0.000
Q85 Phakomatoses, not elsewhere classified	0.620	0.380	0.000
Q84 Other congenital malformations of integument	0.620	0.380	0.000
Q81 Epidermolysis bullosa	0.620	0.380	0.000
Q80 Congenital ichthyosis	0.620	0.380	0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs	0.620	0.380	0.000
C38 Malignant neoplasm of heart, mediastinum and pleura	0.620	0.380	0.000
C31 Malignant neoplasm of accessory sinuses	0.620	0.380	0.000
C30 Malignant neoplasm of nasal cavity and middle ear	0.620	0.380	0.000
C37 Malignant neoplasm of thymus	0.620	0.380	0.000
C33 Malignant neoplasm of trachea	0.620	0.380	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.619	0.381	0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.619	0.381	0.000
I27.8 Other specified pulmonary heart diseases	0.619	0.381	0.000
I27.1 Kyphoscoliotic heart disease	0.619	0.381	0.000
T38.9 Other and unspecified hormone antagonists	0.618	0.382	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.618	0.382	0.000
T38.7 Androgens and anabolic congeners	0.618	0.382	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.618	0.382	0.000
T38.5 Other oestrogens and progestogens	0.618	0.382	0.000
T38.4 Oral contraceptives	0.618	0.382	0.000
T38.2 Antithyroid drugs	0.618	0.382	0.000
T38.1 Thyroid hormones and substitutes	0.618	0.382	0.000
T38.0 Glucocorticoids and synthetic analogues	0.618	0.382	0.000
T63 Toxic effect of contact with venomous animals	0.617	0.383	0.000
I65.2 Occlusion and stenosis of carotid artery	0.617	0.383	0.000
T51.8 Other alcohols	0.616	0.383	0.000
T51.3 Fusel oil	0.616	0.383	0.000
T51.2 2-Propanol	0.616	0.383	0.000
T51.1 Methanol	0.616	0.383	0.000
J70 Respiratory conditions due to other external agents	0.000	0.384	0.616
J68 Respiratory conditions due to inhalation of chemicals, gases, fumes and vapours	0.000	0.384	0.616
J67 Hypersensitivity pneumonitis due to organic dust	0.000	0.384	0.616
J66 Airway disease due to specific organic dust	0.000	0.384	0.616
J63 Pneumoconiosis due to other inorganic dusts	0.000	0.384	0.616
J62 Pneumoconiosis due to dust containing silica	0.000	0.384	0.616
J65 Pneumoconiosis associated with tuberculosis	0.000	0.384	0.616
J64 Unspecified pneumoconiosis	0.000	0.384	0.616
J60 Coalworker's pneumoconiosis	0.000	0.384	0.616
E07 Other disorders of thyroid	0.013	0.384	0.603
C19 Malignant neoplasm of rectosigmoid junction	0.615	0.385	0.000
J36 Peritonsillar abscess	0.000	0.387	0.613
I05-I09 Chronic rheumatic heart diseases	0.613	0.387	0.000
M13.92 Arthritis, unspecified (Upper arm)	0.612	0.388	0.000
C21.8 Overlapping lesion of rectum, anus and anal canal	0.612	0.388	0.000
C21.2 Cloacogenic zone	0.612	0.388	0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.611	0.389	0.000
S32 Fracture of lumbar spine and pelvis	0.611	0.389	0.000
F60.3 Emotionally unstable personality disorder	0.609	0.390	0.000
F41.1 Generalised anxiety disorder	0.609	0.391	0.000
C12 Malignant neoplasm of pyriform sinus	0.609	0.391	0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.609	0.391	0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.609	0.391	0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.609	0.391	0.000
F60.9 Personality disorder, unspecified	0.609	0.391	0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.608	0.392	0.000
C18.8 Overlapping lesion of colon	0.608	0.392	0.000
C18.1 Appendix	0.608	0.392	0.000
L71 Rosacea	0.604	0.396	0.000
J20-J22 Other acute lower respiratory infections	0.000	0.396	0.604
T17 Foreign body in respiratory tract	0.602	0.398	0.000
C25.9 Pancreas, unspecified	0.601	0.399	0.000
U80 Agent resistant to penicillin and related antibiotics	0.601	0.399	0.000
C92 Myeloid leukaemia	0.601	0.399	0.000
T95 Sequelae of burns, corrosions and frostbite	0.598	0.402	0.000
T94 Sequelae of injuries involving multiple and unspecified body regions	0.598	0.402	0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.598	0.402	0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.598	0.402	0.000
F48 Other neurotic disorders	0.598	0.402	0.000
F44 Dissociative [conversion] disorders	0.598	0.402	0.000
G71 Primary disorders of muscles	0.597	0.402	0.000
I25.8 Other forms of chronic ischaemic heart disease	0.594	0.406	0.000
M46 Other inflammatory spondylopathies	0.594	0.406	0.000
F80-F89 Disorders of psychological development	0.593	0.406	0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.593	0.407	0.000
G70 Myasthenia gravis and other myoneural disorders	0.593	0.407	0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified	0.593	0.407	0.000
D46.9 Myelodysplastic syndrome, unspecified	0.593	0.407	0.000
L73 Other follicular disorders	0.593	0.407	0.000
E11 Non-insulin-dependent diabetes mellitus	0.584	0.408	0.008
S98 Traumatic amputation of ankle and foot	0.592	0.408	0.000
S97 Crushing injury of ankle and foot	0.592	0.408	0.000
S96 Injury of muscle and tendon at ankle and foot level	0.592	0.408	0.000
S95 Injury of blood vessels at ankle and foot level	0.592	0.408	0.000
S94 Injury of nerves at ankle and foot level	0.592	0.408	0.000
S91 Open wound of ankle and foot	0.592	0.408	0.000
G24 Dystonia	0.592	0.408	0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere	0.591	0.409	0.000
M66 Spontaneous rupture of synovium and tendon	0.591	0.409	0.000
J30.2 Other seasonal allergic rhinitis	0.000	0.409	0.591
J30.0 Vasomotor rhinitis	0.000	0.409	0.591
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.591	0.409	0.000
J00-J06 Acute upper respiratory infections	0.000	0.409	0.590
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.590	0.410	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.589	0.411	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.589	0.411	0.000
T47.7 Emetics	0.589	0.411	0.000
T47.6 Antidiarrhoeal drugs	0.589	0.411	0.000
T47.5 Digestants	0.589	0.411	0.000
T47.4 Other laxatives	0.589	0.411	0.000
T47.3 Saline and osmotic laxatives	0.589	0.411	0.000
T47.2 Stimulant laxatives	0.589	0.411	0.000
T47.0 Histamine H(2)-receptor antagonists	0.589	0.411	0.000
F30 Manic episode	0.589	0.411	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.589	0.411	0.000
I24.1 Dressler's syndrome	0.588	0.411	0.000
C32.9 Larynx, unspecified	0.588	0.412	0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.587	0.413	0.000
Q21.1 Atrial septal defect	0.587	0.413	0.000
M13.94 Arthritis, unspecified (Hand)	0.586	0.414	0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.586	0.414	0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.586	0.414	0.000
C22.9 Liver, unspecified	0.585	0.415	0.000
C15 Malignant neoplasm of oesophagus	0.585	0.415	0.000
D45 Polycythaemia vera	0.584	0.416	0.000
C18.3 Hepatic flexure	0.584	0.416	0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.583	0.417	0.000
I11 Hypertensive heart disease	0.582	0.418	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations