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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs115907570
log Bayes Factor = 20.1805
Chromosome 1   position 216,193,231  (GRCh37) Explore rs115907570 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
1.000 0.000 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
1.000 0.000 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
1.000 0.000 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.998 0.002 0.000
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified
0.998 0.002 0.000
L98.9 Disorder of skin and subcutaneous tissue, unspecified
0.998 0.002 0.000
M50-M54 Other dorsopathies
0.998 0.002 0.000
R07 Pain in throat and chest
0.996 0.004 0.000
Chapter V Mental and behavioural disorders
0.995 0.005 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.991 0.009 0.000
K44.9 Diaphragmatic hernia without obstruction or gangrene
0.990 0.010 0.000
M05-M14 Inflammatory polyarthropathies
0.990 0.010 0.000
K44 Diaphragmatic hernia
0.988 0.012 0.000
Chapter VI Diseases of the nervous system
0.987 0.013 0.000
Chapter XI Diseases of the digestive system
0.987 0.013 0.000
K40-K46 Hernia
0.985 0.015 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.984 0.016 0.000
M54 Dorsalgia
0.981 0.019 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.980 0.020 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.979 0.021 0.000
R07.4 Chest pain, unspecified
0.975 0.025 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.973 0.027 0.000
Chapter XXI Factors influencing health status and contact with health services
0.971 0.029 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.963 0.037 0.000
E70-E90 Metabolic disorders
0.960 0.040 0.000
Chapter II Neoplasms
0.959 0.041 0.000
R05 Cough
0.958 0.042 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.957 0.043 0.000
G20-G26 Extrapyramidal and movement disorders
0.956 0.044 0.000
Chapter VIII Diseases of the ear and mastoid process
0.955 0.045 0.000
M54.5 Low back pain
0.954 0.046 0.000
M51 Other intervertebral disk disorders
0.953 0.047 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.951 0.049 0.000
Chapter IX Diseases of the circulatory system
0.948 0.052 0.000
Chapter XIV Diseases of the genitourinary system
0.947 0.053 0.000
T81 Complications of procedures, not elsewhere classified
0.946 0.054 0.000
M13 Other arthritis
0.944 0.056 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.944 0.056 0.000
T66-T78 Other and unspecified effects of external causes
0.937 0.063 0.000
M45-M49 Spondylopathies
0.936 0.064 0.000
E78.5 Hyperlipidaemia, unspecified
0.935 0.065 0.000
R07.3 Other chest pain
0.932 0.068 0.000
G30-G32 Other degenerative diseases of the nervous system
0.928 0.072 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.926 0.074 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.923 0.077 0.000
G20 Parkinson's disease
0.922 0.078 0.000
M54.56 Low back pain (Lumbar region)
0.917 0.083 0.000
F10.1 Harmful use
0.916 0.084 0.000
T81.4 Infection following a procedure, not elsewhere classified
0.916 0.084 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.915 0.085 0.000
M13.9 Arthritis, unspecified
0.911 0.089 0.000
M06 Other rheumatoid arthritis
0.909 0.091 0.000
N10-N16 Renal tubulo-interstitial diseases
0.909 0.091 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.907 0.093 0.000
E20-E35 Disorders of other endocrine glands
0.907 0.093 0.000
M51.2 Other specified intervertebral disk displacement
0.906 0.094 0.000
D10-D36 Benign neoplasms
0.902 0.098 0.000
Z88.1 Personal history of allergy to other antibiotic agents
0.902 0.098 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.901 0.099 0.000
T78 Adverse effects, not elsewhere classified
0.898 0.102 0.000
I60-I69 Cerebrovascular diseases
0.897 0.103 0.000
F10.2 Dependence syndrome
0.897 0.103 0.000
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified
0.894 0.106 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.892 0.108 0.000
N13 Obstructive and reflux uropathy
0.891 0.109 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.891 0.109 0.000
Chapter I Certain infectious and parasitic diseases
0.889 0.111 0.000
Z88.6 Personal history of allergy to analgesic agent
0.888 0.112 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.881 0.119 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.878 0.122 0.000
R07.2 Precordial pain
0.878 0.122 0.000
K90-K93 Other diseases of the digestive system
0.878 0.122 0.000
M54.2 Cervicalgia
0.876 0.123 0.000
R26 Abnormalities of gait and mobility
0.876 0.124 0.000
L40-L45 Papulosquamous disorders
0.874 0.126 0.000
H90-H95 Other disorders of ear
0.874 0.126 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.874 0.126 0.000
Z86 Personal history of certain other diseases
0.873 0.127 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.867 0.133 0.000
I95 Hypotension
0.863 0.137 0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction
0.863 0.137 0.000
D12.5 Sigmoid colon
0.861 0.139 0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal
0.860 0.140 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.859 0.141 0.000
M13.99 Arthritis, unspecified (Site unspecified)
0.858 0.142 0.000
M47 Spondylosis
0.857 0.143 0.000
Z86.6 Personal history of diseases of the nervous system and sense organs
0.856 0.144 0.000
D24 Benign neoplasm of breast
0.856 0.144 0.000
C15-C26 Malignant neoplasms of digestive organs
0.855 0.145 0.000
H65-H75 Diseases of middle ear and mastoid
0.853 0.147 0.000
I95.9 Hypotension, unspecified
0.851 0.149 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.849 0.151 0.000
R25 Abnormal involuntary movements
0.848 0.152 0.000
M54.59 Low back pain (Site unspecified)
0.848 0.152 0.000
E78.0 Pure hypercholesterolaemia
0.845 0.155 0.000
O60-O75 Complications of labour and delivery
0.839 0.161 0.000
T78.3 Angioneurotic oedema
0.839 0.161 0.000
E83 Disorders of mineral metabolism
0.837 0.163 0.000
M06.9 Rheumatoid arthritis, unspecified
0.837 0.163 0.000
Z98 Other postsurgical states
0.834 0.166 0.000
Z91.0 Personal history of allergy, other than to drugs and biological substances
0.834 0.166 0.000
R27 Other lack of coordination
0.833 0.167 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.832 0.168 0.000
F10.3 Withdrawal state
0.831 0.169 0.000
L60-L75 Disorders of skin appendages
0.829 0.171 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.829 0.171 0.000
Z93 Artificial opening status
0.828 0.172 0.000
R29.6 Tendency to fall, not elsewhere classified
0.827 0.173 0.000
L89 Decubitus ulcer
0.825 0.175 0.000
M54.1 Radiculopathy
0.821 0.179 0.000
Z91.5 Personal history of self-harm
0.821 0.179 0.000
R02 Gangrene, not elsewhere classified
0.821 0.179 0.000
A30-A49 Other bacterial diseases
0.818 0.182 0.000
R79 Other abnormal findings of blood chemistry
0.818 0.182 0.000
R06 Abnormalities of breathing
0.816 0.184 0.000
F30-F39 Mood [affective] disorders
0.815 0.185 0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.813 0.187 0.000
D22 Melanocytic naevi
0.811 0.189 0.000
L98.8 Other specified disorders of skin and subcutaneous tissue
0.811 0.189 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.810 0.190 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.810 0.190 0.000
M11 Other crystal arthropathies
0.809 0.191 0.000
H91 Other hearing loss
0.807 0.193 0.000
M50 Cervical disk disorders
0.805 0.195 0.000
R47-R49 Symptoms and signs involving speech and voice
0.802 0.198 0.000
M13.91 Arthritis, unspecified (Shoulder region)
0.799 0.201 0.000
M65-M68 Disorders of synovium and tendon
0.799 0.201 0.000
M13.90 Arthritis, unspecified (Multiple sites)
0.799 0.201 0.000
Z86.5 Personal history of other mental and behavioural disorders
0.798 0.202 0.000
M40-M43 Deforming dorsopathies
0.797 0.203 0.000
Z81 Family history of mental and behavioural disorders
0.797 0.203 0.000
K41 Femoral hernia
0.796 0.204 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.795 0.205 0.000
L40 Psoriasis
0.791 0.209 0.000
Z89 Acquired absence of limb
0.788 0.212 0.000
L85 Other epidermal thickening
0.788 0.212 0.000
C18 Malignant neoplasm of colon
0.787 0.213 0.000
I05-I09 Chronic rheumatic heart diseases
0.786 0.214 0.000
M10 Gout
0.784 0.216 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.781 0.219 0.000
K44.0 Diaphragmatic hernia with obstruction, without gangrene
0.778 0.222 0.000
Z93.2 Ileostomy status
0.778 0.222 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.777 0.223 0.000
G31.9 Degenerative disease of nervous system, unspecified
0.777 0.223 0.000
Z95.4 Presence of other heart-valve replacement
0.776 0.224 0.000
T78.2 Anaphylactic shock, unspecified
0.776 0.224 0.000
R81 Glycosuria
0.774 0.226 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.774 0.226 0.000
E83.1 Disorders of iron metabolism
0.771 0.229 0.000
H72 Perforation of tympanic membrane
0.771 0.229 0.000
C79 Secondary malignant neoplasm of other sites
0.771 0.229 0.000
I20-I25 Ischaemic heart diseases
0.771 0.229 0.000
N60-N64 Disorders of breast
0.771 0.229 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.770 0.230 0.000
I69 Sequelae of cerebrovascular disease
0.769 0.231 0.000
M54.22 Cervicalgia (Cervical region)
0.769 0.231 0.000
T79-T79 Certain early complications of trauma
0.768 0.232 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.768 0.232 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.766 0.234 0.000
S80-S89 Injuries to the knee and lower leg
0.766 0.234 0.000
K50-K52 Noninfective enteritis and colitis
0.765 0.235 0.000
N20-N23 Urolithiasis
0.763 0.237 0.000
F60-F69 Disorders of adult personality and behaviour
0.763 0.237 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.763 0.237 0.000
G40-G47 Episodic and paroxysmal disorders
0.762 0.238 0.000
M51.9 Intervertebral disk disorder, unspecified
0.760 0.240 0.000
M47.8 Other spondylosis
0.759 0.241 0.000
E23 Hypofunction and other disorders of pituitary gland
0.759 0.241 0.000
H91.9 Hearing loss, unspecified
0.758 0.242 0.000
Z98.8 Other specified postsurgical states
0.758 0.242 0.000
A41 Other septicaemia
0.758 0.242 0.000
G31.8 Other specified degenerative diseases of nervous system
0.757 0.243 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.756 0.244 0.000
N40-N51 Diseases of male genital organs
0.755 0.245 0.000
F10.0 Acute intoxication
0.755 0.245 0.000
M20-M25 Other joint disorders
0.753 0.247 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.752 0.248 0.000
I67 Other cerebrovascular diseases
0.752 0.248 0.000
G25 Other extrapyramidal and movement disorders
0.752 0.248 0.000
L05 Pilonidal cyst
0.752 0.248 0.000
R73 Elevated blood glucose level
0.751 0.249 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.750 0.250 0.000
M86-M90 Other osteopathies
0.750 0.250 0.000
F10.4 Withdrawal state with delirium
0.750 0.250 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.750 0.250 0.000
N30-N39 Other diseases of urinary system
0.750 0.250 0.000
N13.4 Hydroureter
0.750 0.250 0.000
R26.8 Other and unspecified abnormalities of gait and mobility
0.749 0.250 0.000
M48 Other spondylopathies
0.749 0.251 0.000
Z88.4 Personal history of allergy to anaesthetic agent
0.747 0.253 0.000
N25-N29 Other disorders of kidney and ureter
0.746 0.254 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.745 0.255 0.000
Chapter XX External causes of morbidity and mortality
0.745 0.255 0.000
R25.1 Tremor, unspecified
0.739 0.261 0.000
D22.5 Melanocytic naevi of trunk
0.739 0.261 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.738 0.262 0.000
S00-S09 Injuries to the head
0.737 0.263 0.000
F43 Reaction to severe stress, and adjustment disorders
0.737 0.263 0.000
R03.1 Nonspecific low blood-pressure reading
0.737 0.263 0.000
M91-M94 Chondropathies
0.737 0.263 0.000
F80-F89 Disorders of psychological development
0.735 0.265 0.000
F41 Other anxiety disorders
0.734 0.266 0.000
Chapter XXII Codes for special purposes
0.734 0.266 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.731 0.269 0.000
G90-G99 Other disorders of the nervous system
0.730 0.270 0.000
M50.3 Other cervical disk degeneration
0.730 0.270 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.730 0.270 0.000
H60-H62 Diseases of external ear
0.729 0.271 0.000
D45 Polycythaemia vera
0.729 0.271 0.000
S90-S99 Injuries to the ankle and foot
0.729 0.271 0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.728 0.271 0.000
L91 Hypertrophic disorders of skin
0.728 0.272 0.000
L50-L54 Urticaria and erythema
0.728 0.272 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.728 0.272 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.727 0.273 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.727 0.273 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.724 0.276 0.000
R27.0 Ataxia, unspecified
0.724 0.276 0.000
G24 Dystonia
0.723 0.277 0.000
R80 Isolated proteinuria
0.722 0.278 0.000
Z91.6 Personal history of other physical trauma
0.722 0.278 0.000
S70-S79 Injuries to the hip and thigh
0.721 0.278 0.000
E27 Other disorders of adrenal gland
0.721 0.279 0.000
Z88.3 Personal history of allergy to other anti-infective agents
0.721 0.279 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.720 0.280 0.000
F99-F99 Unspecified mental disorder
0.720 0.280 0.000
T81.8 Other complications of procedures, not elsewhere classified
0.720 0.280 0.000
G31.2 Degeneration of nervous system due to alcohol
0.719 0.280 0.000
M46 Other inflammatory spondylopathies
0.719 0.281 0.000
R79.8 Other specified abnormal findings of blood chemistry
0.719 0.281 0.000
Z88.9 Personal history of allergy to unspecified drugs, medicaments and biological substances
0.719 0.281 0.000
M54.3 Sciatica
0.718 0.282 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.717 0.283 0.000
C25 Malignant neoplasm of pancreas
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
M47.9 Spondylosis, unspecified
0.717 0.283 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.717 0.283 0.000
L10-L14 Bullous disorders
0.717 0.283 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.717 0.283 0.000
I25 Chronic ischaemic heart disease
0.716 0.284 0.000
L90 Atrophic disorders of skin
0.716 0.284 0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.716 0.284 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.716 0.284 0.000
L94 Other localised connective tissue disorders
0.716 0.284 0.000
L93 Lupus erythematosus
0.716 0.284 0.000
L87 Transepidermal elimination disorders
0.716 0.284 0.000
L88 Pyoderma gangrenosum
0.716 0.284 0.000
L86 Keratoderma in diseases classified elsewhere
0.716 0.284 0.000
L83 Acanthosis nigricans
0.716 0.284 0.000
L80 Vitiligo
0.716 0.284 0.000
L98.7 Excessive and redundant skin and subcutaneous tissue
0.715 0.284 0.000
L98.6 Other infiltrative disorders of skin and subcutaneous tissue
0.715 0.284 0.000
L98.5 Mucinosis of skin
0.715 0.284 0.000
L98.4 Chronic ulcer of skin, not elsewhere classified
0.715 0.284 0.000
L98.3 Eosinophilic cellulitis [Wells]
0.715 0.284 0.000
L98.2 Febrile neutrophilic dermatosis [Sweet]
0.715 0.284 0.000
L98.1 Factitial dermatitis
0.715 0.284 0.000
M53 Other dorsopathies, not elsewhere classified
0.715 0.285 0.000
M07 Psoriatic and enteropathic arthropathies
0.715 0.285 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.714 0.286 0.000
R07.1 Chest pain on breathing
0.714 0.286 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.714 0.286 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.713 0.286 0.000
F70-F79 Mental retardation
0.713 0.286 0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction
0.713 0.287 0.000
D35 Benign neoplasm of other and unspecified endocrine glands
0.713 0.287 0.000
H72.9 Perforation of tympanic membrane, unspecified
0.712 0.288 0.000
K65-K67 Diseases of peritoneum
0.712 0.288 0.000
T33-T35 Frostbite
0.711 0.289 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.711 0.289 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.711 0.289 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.711 0.289 0.000
T00-T07 Injuries involving multiple body regions
0.711 0.289 0.000
S10-S19 Injuries to the neck
0.711 0.289 0.000
M13.97 Arthritis, unspecified (Ankle and foot)
0.710 0.290 0.000
M14 Arthropathies in other diseases classified elsewhere
0.710 0.290 0.000
M12 Other specific arthropathies
0.710 0.290 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.710 0.290 0.000
M08 Juvenile arthritis
0.710 0.290 0.000
N00-N08 Glomerular diseases
0.710 0.290 0.000
D10 Benign neoplasm of mouth and pharynx
0.709 0.291 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.708 0.291 0.000
K44.1 Diaphragmatic hernia with gangrene
0.708 0.292 0.000
G70-G73 Diseases of myoneural junction and muscle
0.708 0.292 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.708 0.292 0.000
F32 Depressive episode
0.707 0.293 0.000
M54.16 Radiculopathy (Lumbar region)
0.707 0.293 0.000
K45 Other abdominal hernia
0.706 0.294 0.000
L57 Skin changes due to chronic exposure to nonionising radiation
0.706 0.294 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.706 0.294 0.000
I61 Intracerebral haemorrhage
0.706 0.294 0.000
L20-L30 Dermatitis and eczema
0.705 0.295 0.000
M06.0 Seronegative rheumatoid arthritis
0.704 0.296 0.000
M54.29 Cervicalgia-Site unspe
0.704 0.296 0.000
D26 Other benign neoplasms of uterus
0.704 0.296 0.000
M54.8 Other dorsalgia
0.704 0.296 0.000
M54.6 Pain in thoracic spine
0.704 0.296 0.000
M54.0 Panniculitis affecting regions of neck and back
0.704 0.296 0.000
E28 Ovarian dysfunction
0.704 0.296 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.703 0.297 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.702 0.298 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.702 0.298 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.702 0.298 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.702 0.298 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.702 0.298 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.702 0.298 0.000
F11 Mental and behavioural disorders due to use of opioids
0.702 0.298 0.000
L73 Other follicular disorders
0.702 0.298 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.702 0.298 0.000
E40-E46 Malnutrition
0.702 0.298 0.000
Z95.1 Presence of aortocoronary bypass graft
0.701 0.299 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.701 0.299 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.700 0.299 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.700 0.300 0.000
C18.7 Sigmoid colon
0.700 0.300 0.000
K46 Unspecified abdominal hernia
0.699 0.301 0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy
0.699 0.301 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.698 0.302 0.000
F10.9 Unspecified mental and behavioural disorder
0.697 0.303 0.000
F10.8 Other mental and behavioural disorders
0.697 0.303 0.000
F10.7 Residual and late-onset psychotic disorder
0.697 0.303 0.000
F10.6 Amnesic syndrome
0.697 0.303 0.000
F10.5 Psychotic disorder
0.697 0.303 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.697 0.303 0.000
R76 Other abnormal immunological findings in serum
0.696 0.304 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.695 0.305 0.000
R04 Haemorrhage from respiratory passages
0.694 0.306 0.000
D00-D09 In situ neoplasms
0.694 0.306 0.000
R74 Abnormal serum enzyme levels
0.691 0.309 0.000
Z84 Family history of other conditions
0.691 0.309 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.690 0.310 0.000
D13 Benign neoplasm of other and ill-defined parts of digestive system
0.690 0.310 0.000
H93 Other disorders of ear, not elsewhere classified
0.690 0.310 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.689 0.311 0.000
R26.0 Ataxic gait
0.689 0.311 0.000
G30 Alzheimer's disease
0.689 0.311 0.000
E88 Other metabolic disorders
0.688 0.311 0.000
E85 Amyloidosis
0.688 0.311 0.000
E84 Cystic fibrosis
0.688 0.311 0.000
E79 Disorders of purine and pyrimidine metabolism
0.688 0.311 0.000
E77 Disorders of glycoprotein metabolism
0.688 0.311 0.000
E76 Disorders of glycosaminoglycan metabolism
0.688 0.311 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.688 0.311 0.000
E74 Other disorders of carbohydrate metabolism
0.688 0.311 0.000
E73 Lactose intolerance
0.688 0.311 0.000
E72 Other disorders of amino-acid metabolism
0.688 0.311 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.688 0.311 0.000
E70 Disorders of aromatic amino-acid metabolism
0.688 0.311 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.688 0.311 0.000
K91.3 Postoperative intestinal obstruction
0.688 0.312 0.000
A00-A09 Intestinal infectious diseases
0.688 0.312 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.688 0.312 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.688 0.312 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.688 0.312 0.000
T87 Complications peculiar to reattachment and amputation
0.686 0.313 0.000
T86 Failure and rejection of transplanted organs and tissues
0.686 0.313 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.686 0.313 0.000
I60 Subarachnoid haemorrhage
0.686 0.313 0.000
L40.5 Arthropathic psoriasis
0.686 0.313 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.686 0.314 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.686 0.314 0.000
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified
0.686 0.314 0.000
C18.9 Colon, unspecified
0.686 0.314 0.000
G23 Other degenerative diseases of basal ganglia
0.685 0.314 0.000
G21 Secondary Parkinsonism
0.685 0.314 0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere
0.685 0.314 0.000
G22 Parkinsonism in diseases classified elsewhere
0.685 0.314 0.000
B35-B49 Mycoses
0.685 0.315 0.000
M54.55 Low back pain (Thoracolumbar region)
0.684 0.316 0.000
M54.54 Low back pain-Thoracic
0.684 0.316 0.000
M54.53 Low back pain-Cervicothoracic
0.684 0.316 0.000
M54.52 Low back pain-Cervical
0.684 0.316 0.000
M54.51 Low back pain-Occipit-atl-axl
0.684 0.316 0.000
M54.50 Low back pain (Multiple sites in spine)
0.684 0.316 0.000
D12.4 Descending colon
0.684 0.316 0.000
Z88.2 Personal history of allergy to sulphonamides
0.684 0.316 0.000
M51.3 Other specified intervertebral disk degeneration
0.683 0.316 0.000
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy
0.683 0.316 0.000
M51.8 Other specified intervertebral disk disorders
0.683 0.316 0.000
M51.4 Schmorl's nodes
0.683 0.316 0.000
R72 Abnormality of white blood cells, not elsewhere classified
0.683 0.316 0.000
N63 Unspecified lump in breast
0.683 0.317 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.682 0.317 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.682 0.318 0.000
E78.8 Other disorders of lipoprotein metabolism
0.682 0.318 0.000
E78.6 Lipoprotein deficiency
0.682 0.318 0.000
E78.4 Other hyperlipidaemia
0.682 0.318 0.000
E78.3 Hyperchylomicronaemia
0.682 0.318 0.000
E78.2 Mixed hyperlipidaemia
0.682 0.318 0.000
E78.1 Pure hyperglyceridaemia
0.682 0.318 0.000
Z88.7 Personal history of allergy to serum and vaccine
0.680 0.320 0.000
S60-S69 Injuries to the wrist and hand
0.680 0.320 0.000
I00-I02 Acute rheumatic fever
0.679 0.321 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.679 0.321 0.000
N39 Other disorders of urinary system
0.679 0.321 0.000
R25.8 Other and unspecified abnormal involuntary movements
0.679 0.321 0.000
M11.2 Other chondrocalcinosis
0.678 0.322 0.000
T81.9 Unspecified complication of procedure
0.678 0.322 0.000
T81.7 Vascular complications following a procedure, not elsewhere classified
0.678 0.322 0.000
T81.6 Acute reaction to foreign substance accidentally left during a procedure
0.678 0.322 0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure
0.678 0.322 0.000
T81.1 Shock during or resulting from a procedure, not elsewhere classified
0.678 0.322 0.000
K90 Intestinal malabsorption
0.678 0.322 0.000
Z81.8 Family history of other mental and behavioural disorders
0.677 0.323 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.677 0.323 0.000
M13.8 Other specified arthritis
0.677 0.323 0.000
M13.1 Monoarthritis, not elsewhere classified
0.677 0.323 0.000
M13.0 Polyarthritis, unspecified
0.677 0.323 0.000
Z93.0 Tracheostomy status
0.677 0.323 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.677 0.323 0.000
F41.2 Mixed anxiety and depressive disorder
0.676 0.324 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.676 0.324 0.000
L60 Nail disorders
0.675 0.325 0.000
D50-D53 Nutritional anaemias
0.673 0.327 0.000
M45 Ankylosing spondylitis
0.673 0.327 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.673 0.327 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.673 0.327 0.000
M05 Seropositive rheumatoid arthritis
0.673 0.327 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.672 0.328 0.000
T75 Effects of other external causes
0.672 0.328 0.000
T74 Maltreatment syndromes
0.672 0.328 0.000
T73 Effects of other deprivation
0.672 0.328 0.000
T70 Effects of air pressure and water pressure
0.672 0.328 0.000
T69 Other effects of reduced temperature
0.672 0.328 0.000
T67 Effects of heat and light
0.672 0.328 0.000
T71 Asphyxiation
0.672 0.328 0.000
T68 Hypothermia
0.672 0.328 0.000
T66 Unspecified effects of radiation
0.672 0.328 0.000
D22.4 Melanocytic naevi of scalp and neck
0.672 0.328 0.000
M49 Spondylopathies in diseases classified elsewhere
0.671 0.329 0.000
Z94 Transplanted organ and tissue status
0.671 0.329 0.000
L08 Other local infections of skin and subcutaneous tissue
0.671 0.329 0.000
R06.0 Dyspnoea
0.671 0.329 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.671 0.329 0.000
F40 Phobic anxiety disorders
0.670 0.330 0.000
F45 Somatoform disorders
0.670 0.330 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.670 0.330 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.668 0.332 0.000
L89.9 Decubitus ulcer and pressure area, unspecified
0.668 0.332 0.000
M54.4 Lumbago with sciatica
0.668 0.332 0.000
S20-S29 Injuries to the thorax
0.668 0.332 0.000
N47 Redundant prepuce, phimosis and paraphimosis
0.667 0.333 0.000
C51-C58 Malignant neoplasms of female genital organs
0.667 0.333 0.000
K86 Other diseases of pancreas
0.666 0.334 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.665 0.335 0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.665 0.335 0.000
M80-M85 Disorders of bone density and structure
0.665 0.335 0.000
R78 Findings of drugs and other substances, not normally found in blood
0.664 0.336 0.000
R77 Other abnormalities of plasma proteins
0.664 0.336 0.000
R70 Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity
0.664 0.336 0.000
R75 Laboratory evidence of human immunodeficiency virus [HIV]
0.664 0.336 0.000
R71 Abnormality of red blood cells
0.664 0.336 0.000
K35-K38 Diseases of appendix
0.664 0.336 0.000
L84 Corns and callosities
0.663 0.337 0.000
R85 Abnormal findings in specimens from digestive organs and abdominal cavity
0.663 0.337 0.000
Z91.8 Personal history of other specified risk-factors, not elsewhere classified
0.662 0.338 0.000
Z91.7 Personal history of female genital mutilation
0.662 0.338 0.000
Z91.4 Personal history of psychological trauma, not elsewhere classified
0.662 0.338 0.000
Z91.3 Personal history of unhealthy sleep-wake schedule
0.662 0.338 0.000
Z91.2 Personal history of poor personal hygiene
0.662 0.338 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.662 0.338 0.000
L40.9 Psoriasis, unspecified
0.662 0.338 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.662 0.338 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.661 0.339 0.000
K41.9 Unilateral or unspecified femoral hernia, without obstruction or gangrene
0.661 0.339 0.000
R26.3 Immobility
0.661 0.339 0.000
D36 Benign neoplasm of other and unspecified sites
0.659 0.341 0.000
O63 Long labour
0.658 0.342 0.000
Z97 Presence of other devices
0.658 0.342 0.000
K91.4 Colostomy and enterostomy malfunction
0.658 0.342 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.657 0.343 0.000
N39.0 Urinary tract infection, site not specified
0.657 0.343 0.000
N64 Other disorders of breast
0.656 0.344 0.000
O85-O92 Complications predominantly related to the puerperium
0.656 0.344 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.655 0.345 0.000
L71 Rosacea
0.654 0.346 0.000
E21.0 Primary hyperparathyroidism
0.654 0.346 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.654 0.346 0.000
H66 Suppurative and unspecified otitis media
0.654 0.346 0.000
M47.99 Spondylosis, unspecified (Site unspecified)
0.654 0.346 0.000
M13.93 Arthritis, unspecified (Forearm)
0.653 0.347 0.000
M13.92 Arthritis, unspecified (Upper arm)
0.653 0.347 0.000
E23.0 Hypopituitarism
0.653 0.347 0.000
M06.8 Other specified rheumatoid arthritis
0.652 0.348 0.000
M06.4 Inflammatory polyarthropathy
0.652 0.348 0.000
M06.3 Rheumatoid nodule
0.652 0.348 0.000
M06.2 Rheumatoid bursitis
0.652 0.348 0.000
M06.1 Adult-onset Still's disease
0.652 0.348 0.000
A41.9 Septicaemia, unspecified
0.652 0.348 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.652 0.348 0.000
N15 Other renal tubulo-interstitial diseases
0.652 0.348 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.652 0.348 0.000
N11 Chronic tubulo-interstitial nephritis
0.652 0.348 0.000
L05.9 Pilonidal cyst without abscess
0.651 0.349 0.000
M13.98 Arthritis, unspecified (Other)
0.650 0.350 0.000
Z95.3 Presence of xenogenic heart valve
0.650 0.350 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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