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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs116045601
log Bayes Factor = 19.3299
Chromosome 2   position 31,490,659  (GRCh37) Explore rs116045601 on Ensembl!
Variant rs116045601 is part of Cluster X0087

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Z00-Z13 Persons encountering health services for examination and investigation
1.000 0.000 0.000
Chapter II Neoplasms
0.998 0.002 0.000
C44 Other malignant neoplasms of skin
0.998 0.002 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.997 0.003 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.994 0.006 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.994 0.006 0.000
Z13 Special screening examination for other diseases and disorders
0.994 0.006 0.000
Chapter IX Diseases of the circulatory system
0.994 0.006 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.993 0.007 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.991 0.009 0.000
Chapter VIII Diseases of the ear and mastoid process
0.991 0.009 0.000
C44.3 Skin of other and unspecified parts of face
0.987 0.013 0.000
I60-I69 Cerebrovascular diseases
0.985 0.015 0.000
M50-M54 Other dorsopathies
0.977 0.023 0.000
Chapter X Diseases of the respiratory system
0.975 0.025 0.000
H90-H95 Other disorders of ear
0.974 0.026 0.000
M54 Dorsalgia
0.971 0.029 0.000
Z03 Medical observation and evaluation for suspected diseases and conditions
0.969 0.031 0.000
Z85 Personal history of malignant neoplasm
0.967 0.033 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.966 0.034 0.000
S80-S89 Injuries to the knee and lower leg
0.962 0.038 0.000
Z13.0 Special screening examination for diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.957 0.043 0.000
Chapter XX External causes of morbidity and mortality
0.956 0.044 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.956 0.044 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.951 0.049 0.000
J90-J94 Other diseases of pleura
0.949 0.051 0.000
C60-C63 Malignant neoplasms of male genital organs
0.947 0.053 0.000
Chapter I Certain infectious and parasitic diseases
0.946 0.054 0.000
C44.2 Skin of ear and external auricular canal
0.946 0.054 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.945 0.055 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.944 0.056 0.000
S00-S09 Injuries to the head
0.943 0.057 0.000
Z51 Other medical care
0.943 0.057 0.000
I63 Cerebral infarction
0.942 0.058 0.000
I69 Sequelae of cerebrovascular disease
0.941 0.059 0.000
I30-I52 Other forms of heart disease
0.938 0.062 0.000
M65-M68 Disorders of synovium and tendon
0.938 0.062 0.000
Z85.8 Personal history of malignant neoplasms of other organs and systems
0.937 0.063 0.000
Z47 Other orthopaedic follow-up care
0.932 0.068 0.000
I35 Nonrheumatic aortic valve disorders
0.931 0.069 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.927 0.073 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.925 0.075 0.000
Z03.1 Observation for suspected malignant neoplasm
0.925 0.075 0.000
Z02 Examination and encounter for administrative purposes
0.924 0.076 0.000
Z85.1 Personal history of malignant neoplasm of trachea, bronchus and lung
0.921 0.079 0.000
Z13.9 Special screening examination, unspecified
0.916 0.084 0.000
H65-H75 Diseases of middle ear and mastoid
0.916 0.084 0.000
Z51.0 Radiotherapy session
0.915 0.085 0.000
J93 Pneumothorax
0.915 0.085 0.000
C44.6 Skin of upper limb, including shoulder
0.914 0.086 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.911 0.089 0.000
M80-M85 Disorders of bone density and structure
0.911 0.089 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.910 0.090 0.000
I35.0 Aortic (valve) stenosis
0.910 0.090 0.000
E65-E68 Obesity and other hyperalimentation
0.907 0.093 0.000
Z41 Procedures for purposes other than remedying health state
0.906 0.094 0.000
T81 Complications of procedures, not elsewhere classified
0.906 0.094 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.905 0.095 0.000
I63.9 Cerebral infarction, unspecified
0.901 0.099 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.900 0.100 0.000
M54.9 Dorsalgia, unspecified
0.897 0.103 0.000
Z93 Artificial opening status
0.896 0.104 0.000
Z43 Attention to artificial openings
0.895 0.105 0.000
S60-S69 Injuries to the wrist and hand
0.893 0.107 0.000
C61 Malignant neoplasm of prostate
0.893 0.107 0.000
E66 Obesity
0.893 0.107 0.000
H90 Conductive and sensorineural hearing loss
0.889 0.111 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.889 0.111 0.000
H91 Other hearing loss
0.885 0.115 0.000
E66.9 Obesity, unspecified
0.884 0.116 0.000
C15-C26 Malignant neoplasms of digestive organs
0.882 0.118 0.000
Z13.1 Special screening examination for diabetes mellitus
0.882 0.118 0.000
I44 Atrioventricular and left bundle-branch block
0.881 0.119 0.000
M54.3 Sciatica
0.880 0.120 0.000
Z34 Supervision of normal pregnancy
0.878 0.122 0.000
A00-A09 Intestinal infectious diseases
0.878 0.122 0.000
T81.4 Infection following a procedure, not elsewhere classified
0.875 0.125 0.000
M65 Synovitis and tenosynovitis
0.872 0.128 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.872 0.128 0.000
J95-J99 Other diseases of the respiratory system
0.871 0.129 0.000
Z02.8 Other examinations for administrative purposes
0.870 0.130 0.000
M54.1 Radiculopathy
0.869 0.131 0.000
Z47.0 Follow-up care involving removal of fracture plate and other internal fixation device
0.868 0.132 0.000
C44.1 Skin of eyelid, including canthus
0.866 0.134 0.000
Z51.5 Palliative care
0.864 0.136 0.000
Z98 Other postsurgical states
0.864 0.136 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.862 0.138 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.861 0.139 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.860 0.140 0.000
M54.99 Dorsalgia, unspecified (Site unspecified)
0.857 0.143 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.856 0.144 0.000
S09 Other and unspecified injuries of head
0.854 0.146 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.854 0.146 0.000
S70-S79 Injuries to the hip and thigh
0.854 0.146 0.000
S82 Fracture of lower leg, including ankle
0.853 0.147 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.852 0.148 0.000
Z33 Pregnant state, incidental
0.851 0.149 0.000
J93.1 Other spontaneous pneumothorax
0.850 0.150 0.000
Z03.9 Observation for suspected disease or condition, unspecified
0.849 0.151 0.000
S80 Superficial injury of lower leg
0.848 0.152 0.000
T39.1 4-Aminophenol derivatives
0.846 0.154 0.000
Z41.1 Other plastic surgery for unacceptable cosmetic appearance
0.843 0.157 0.000
Z85.2 Personal history of malignant neoplasm of other respiratory and intrathoracic organs
0.843 0.157 0.000
J40-J47 Chronic lower respiratory diseases
0.841 0.159 0.000
Chapter VI Diseases of the nervous system
0.838 0.162 0.000
Z36 Antenatal screening
0.838 0.162 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.836 0.164 0.000
C44.7 Skin of lower limb, including hip
0.835 0.165 0.000
M45-M49 Spondylopathies
0.833 0.167 0.000
Z34.9 Supervision of normal pregnancy, unspecified
0.832 0.168 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.830 0.170 0.000
Z03.5 Observation for other suspected cardiovascular diseases
0.829 0.171 0.000
Z83 Family history of other specific disorders
0.829 0.171 0.000
S20-S29 Injuries to the thorax
0.829 0.171 0.000
C25 Malignant neoplasm of pancreas
0.829 0.171 0.000
A30-A49 Other bacterial diseases
0.823 0.177 0.000
S10-S19 Injuries to the neck
0.820 0.180 0.000
H91.9 Hearing loss, unspecified
0.820 0.180 0.000
Z42 Follow-up care involving plastic surgery
0.820 0.180 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.818 0.182 0.000
J93.9 Pneumothorax, unspecified
0.816 0.184 0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts
0.816 0.184 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.813 0.187 0.000
I35.1 Aortic (valve) insufficiency
0.812 0.188 0.000
I05-I09 Chronic rheumatic heart diseases
0.812 0.188 0.000
S50-S59 Injuries to the elbow and forearm
0.811 0.189 0.000
V40-V49 Car occupant injured in transport accident
0.809 0.191 0.000
I67 Other cerebrovascular diseases
0.809 0.191 0.000
D00-D09 In situ neoplasms
0.808 0.192 0.000
J44 Other chronic obstructive pulmonary disease
0.808 0.192 0.000
S00 Superficial injury of head
0.807 0.193 0.000
M86-M90 Other osteopathies
0.805 0.195 0.000
Z93.1 Gastrostomy status
0.805 0.195 0.000
C44.0 Skin of lip
0.804 0.196 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.804 0.196 0.000
B35-B49 Mycoses
0.801 0.199 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.801 0.199 0.000
H92 Otalgia and effusion of ear
0.799 0.201 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.798 0.202 0.000
J90 Pleural effusion, not elsewhere classified
0.797 0.203 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.797 0.203 0.000
J00-J06 Acute upper respiratory infections
0.797 0.203 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.796 0.204 0.000
I86 Varicose veins of other sites
0.795 0.204 0.000
S05 Injury of eye and orbit
0.794 0.206 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.794 0.206 0.000
I80 Phlebitis and thrombophlebitis
0.794 0.206 0.000
M54.39 Sciatica (Site unspecified)
0.793 0.207 0.000
T66-T78 Other and unspecified effects of external causes
0.793 0.207 0.000
H93 Other disorders of ear, not elsewhere classified
0.792 0.208 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.792 0.208 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.792 0.208 0.000
T82.3 Mechanical complication of other vascular grafts
0.791 0.209 0.000
Z45 Adjustment and management of implanted device
0.790 0.210 0.000
Q00-Q07 Congenital malformations of the nervous system
0.789 0.211 0.000
H73 Other disorders of tympanic membrane
0.787 0.213 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.786 0.214 0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts
0.784 0.216 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.783 0.217 0.000
E50-E64 Other nutritional deficiencies
0.783 0.217 0.000
Y83.1 Surgical operation with implant of artificial internal device
0.782 0.218 0.000
Z82.5 Family history of asthma and other chronic lower respiratory diseases
0.782 0.218 0.000
I33 Acute and subacute endocarditis
0.780 0.220 0.000
M67 Other disorders of synovium and tendon
0.780 0.220 0.000
T39.0 Salicylates
0.779 0.221 0.000
I30 Acute pericarditis
0.777 0.223 0.000
Z43.3 Attention to colostomy
0.773 0.227 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.773 0.227 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.772 0.228 0.000
Q60-Q64 Congenital malformations of the urinary system
0.770 0.230 0.000
V20-V29 Motorcycle rider injured in transport accident
0.769 0.231 0.000
C62 Malignant neoplasm of testis
0.768 0.232 0.000
M81 Osteoporosis without pathological fracture
0.768 0.232 0.000
I44.7 Left bundle-branch block, unspecified
0.768 0.232 0.000
Z43.1 Attention to gastrostomy
0.768 0.232 0.000
S09.9 Unspecified injury of head
0.767 0.233 0.000
M54.5 Low back pain
0.765 0.235 0.000
Q50-Q56 Congenital malformations of genital organs
0.764 0.236 0.000
H72 Perforation of tympanic membrane
0.764 0.236 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.763 0.236 0.000
T85.2 Mechanical complication of intraocular lens
0.763 0.237 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.762 0.238 0.000
J92 Pleural plaque
0.762 0.238 0.000
C25.9 Pancreas, unspecified
0.762 0.238 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.761 0.238 0.000
S82.8 Fractures of other parts of lower leg
0.761 0.239 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.760 0.240 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.759 0.241 0.000
H90.5 Sensorineural hearing loss, unspecified
0.759 0.241 0.000
S61 Open wound of wrist and hand
0.756 0.244 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.756 0.244 0.000
M54.4 Lumbago with sciatica
0.754 0.246 0.000
E20-E35 Disorders of other endocrine glands
0.752 0.248 0.000
Z88.8 Personal history of allergy to other drugs, medicaments and biological substances
0.752 0.248 0.000
Z47.8 Other specified orthopaedic follow-up care
0.752 0.248 0.000
J98 Other respiratory disorders
0.752 0.248 0.000
M54.6 Pain in thoracic spine
0.750 0.250 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.750 0.250 0.000
S90-S99 Injuries to the ankle and foot
0.749 0.251 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.748 0.252 0.000
Z99.1 Dependence on respirator
0.746 0.254 0.000
T51 Toxic effect of alcohol
0.746 0.254 0.000
M65.91 Synovitis and tenosynovitis, unspecified (Shoulder region)
0.746 0.254 0.000
G90-G99 Other disorders of the nervous system
0.745 0.255 0.000
I49 Other cardiac arrhythmias
0.744 0.256 0.000
Z98.8 Other specified postsurgical states
0.743 0.257 0.000
Z13.5 Special screening examination for eye and ear disorders
0.743 0.257 0.000
S02 Fracture of skull and facial bones
0.743 0.257 0.000
S80.9 Superficial injury of lower leg, unspecified
0.743 0.257 0.000
C20 Malignant neoplasm of rectum
0.742 0.258 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.741 0.259 0.000
M85 Other disorders of bone density and structure
0.741 0.259 0.000
M47 Spondylosis
0.740 0.260 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.740 0.260 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.740 0.260 0.000
Z51.3 Blood transfusion without reported diagnosis
0.740 0.260 0.000
D03 Melanoma in situ
0.740 0.260 0.000
S64 Injury of nerves at wrist and hand level
0.739 0.260 0.000
Chapter XI Diseases of the digestive system
0.739 0.261 0.000
J02 Acute pharyngitis
0.738 0.262 0.000
A49 Bacterial infection of unspecified site
0.736 0.264 0.000
Z82.3 Family history of stroke
0.736 0.264 0.000
Z93.2 Ileostomy status
0.734 0.266 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.733 0.266 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.733 0.267 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.732 0.268 0.000
Z36.3 Antenatal screening for malformations using ultrasound and other physical methods
0.732 0.268 0.000
Z89 Acquired absence of limb
0.732 0.268 0.000
Chapter VII Diseases of the eye and adnexa
0.729 0.271 0.000
V80-V89 Other land transport accidents
0.729 0.271 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.729 0.271 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.728 0.272 0.000
M91-M94 Chondropathies
0.728 0.272 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.728 0.272 0.000
Z82.0 Family history of epilepsy and other diseases of the nervous system
0.728 0.272 0.000
Z88.7 Personal history of allergy to serum and vaccine
0.728 0.272 0.000
T86 Failure and rejection of transplanted organs and tissues
0.727 0.273 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.727 0.273 0.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system
0.726 0.274 0.000
I86.1 Scrotal varices
0.726 0.274 0.000
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities
0.725 0.275 0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.724 0.276 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.724 0.276 0.000
C64-C68 Malignant neoplasms of urinary tract
0.723 0.277 0.000
Z32 Pregnancy examination and test
0.721 0.279 0.000
H66 Suppurative and unspecified otitis media
0.721 0.279 0.000
M53 Other dorsopathies, not elsewhere classified
0.721 0.279 0.000
S68 Traumatic amputation of wrist and hand
0.721 0.279 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.720 0.280 0.000
Z82.7 Family history of congenital malformations, deformations and chromosomal abnormalities
0.719 0.281 0.000
J60-J70 Lung diseases due to external agents
0.719 0.281 0.000
Z45.8 Adjustment and management of other implanted devices
0.718 0.282 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
Z51.8 Other specified medical care
0.717 0.283 0.000
Z10 Routine general health check-up of defined subpopulation
0.717 0.283 0.000
S72 Fracture of femur
0.716 0.284 0.000
S39.9 Unspecified injury of abdomen, lower back and pelvis
0.716 0.284 0.000
Z86 Personal history of certain other diseases
0.716 0.284 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.716 0.284 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.716 0.284 0.000
C44.9 Malignant neoplasm of skin, unspecified
0.715 0.285 0.000
C44.8 Overlapping lesion of skin
0.715 0.285 0.000
R26 Abnormalities of gait and mobility
0.715 0.285 0.000
Z03.6 Observation for suspected toxic effect from ingested substance
0.715 0.285 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.714 0.285 0.000
Z03.3 Observation for suspected nervous system disorder
0.713 0.287 0.000
Z54 Convalescence
0.713 0.287 0.000
Z44 Fitting and adjustment of external prosthetic device
0.713 0.287 0.000
T87 Complications peculiar to reattachment and amputation
0.713 0.287 0.000
Chapter XXII Codes for special purposes
0.713 0.287 0.000
X60-X84 Intentional self-harm
0.713 0.287 0.000
Z13.8 Special screening examination for other specified diseases and disorders
0.713 0.287 0.000
Z13.7 Special screening examination for congenital malformations, deformations and chromosomal abnormalities
0.713 0.287 0.000
Z13.4 Special screening examination for certain developmental disorders in childhood
0.713 0.287 0.000
Z13.3 Special screening examination for mental and behavioural disorders
0.713 0.287 0.000
Z13.2 Special screening examination for nutritional disorders
0.713 0.287 0.000
H80-H83 Diseases of inner ear
0.713 0.287 0.000
I00-I02 Acute rheumatic fever
0.712 0.288 0.000
I35.8 Other aortic valve disorders
0.712 0.288 0.000
M40-M43 Deforming dorsopathies
0.712 0.288 0.000
S82.1 Fracture of upper end of tibia
0.712 0.288 0.000
M60-M63 Disorders of muscles
0.712 0.288 0.000
M00-M03 Infectious arthropathies
0.712 0.288 0.000
Z83.5 Family history of eye and ear disorders
0.712 0.288 0.000
M80 Osteoporosis with pathological fracture
0.711 0.289 0.000
Z00.6 Examination for normal comparison and control in clinical research programme
0.711 0.289 0.000
Z84 Family history of other conditions
0.710 0.290 0.000
Z81 Family history of mental and behavioural disorders
0.710 0.290 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.710 0.290 0.000
H92.0 Otalgia
0.710 0.290 0.000
Q80-Q89 Other congenital malformations
0.709 0.291 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.709 0.291 0.000
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side
0.709 0.291 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.709 0.291 0.000
Z08.1 Follow-up examination after radiotherapy for malignant neoplasm
0.708 0.292 0.000
X20-X29 Contact with venomous animals and plants
0.708 0.292 0.000
I44.0 Atrioventricular block, first degree
0.708 0.292 0.000
H90.3 Sensorineural hearing loss, bilateral
0.707 0.292 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.706 0.293 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.706 0.293 0.000
Z93.4 Other artificial openings of gastro-intestinal tract status
0.706 0.294 0.000
I69.3 Sequelae of cerebral infarction
0.706 0.294 0.000
M54.18 Radiculopathy (Sacral and sacrococcygeal region)
0.705 0.295 0.000
Z39 Postpartum care and examination
0.705 0.295 0.000
Z35 Supervision of high-risk pregnancy
0.705 0.295 0.000
Z03.8 Observation for other suspected diseases and conditions
0.704 0.296 0.000
M84 Disorders of continuity of bone
0.704 0.296 0.000
S89 Other and unspecified injuries of lower leg
0.704 0.296 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.703 0.297 0.000
T85.4 Mechanical complication of breast prosthesis and implant
0.702 0.298 0.000
Z88.2 Personal history of allergy to sulphonamides
0.702 0.298 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.702 0.298 0.000
S06 Intracranial injury
0.702 0.298 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.701 0.299 0.000
Z94 Transplanted organ and tissue status
0.701 0.299 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.701 0.299 0.000
I82 Other venous embolism and thrombosis
0.701 0.299 0.000
Z99.2 Dependence on renal dialysis
0.701 0.299 0.000
A80-A89 Viral infections of the central nervous system
0.700 0.299 0.000
A08 Viral and other specified intestinal infections
0.699 0.301 0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified
0.699 0.301 0.000
H94 Other disorders of ear in diseases classified elsewhere
0.699 0.301 0.000
M65.94 Synovitis and tenosynovitis, unspecified (Hand)
0.699 0.301 0.000
A09.0 Other and unspecified gastroenteritis and colitis of infectious origin
0.698 0.302 0.000
Z42.1 Follow-up care involving plastic surgery of breast
0.698 0.302 0.000
M54.8 Other dorsalgia
0.696 0.304 0.000
M54.0 Panniculitis affecting regions of neck and back
0.696 0.304 0.000
Z49 Care involving dialysis
0.696 0.304 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.696 0.304 0.000
J02.9 Acute pharyngitis, unspecified
0.696 0.304 0.000
S82.80 Fractures of other parts of lower leg (closed)
0.695 0.305 0.000
Z03.2 Observation for suspected mental and behavioural disorders
0.695 0.305 0.000
Z03.0 Observation for suspected tuberculosis
0.695 0.305 0.000
M54.12 Radiculopathy (Cervical region)
0.695 0.305 0.000
H73.8 Other specified disorders of tympanic membrane
0.694 0.306 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.694 0.306 0.000
I44.2 Atrioventricular block, complete
0.694 0.306 0.000
Z08.7 Follow-up examination after combined treatment for malignant neoplasm
0.694 0.306 0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.693 0.307 0.000
M54.36 Sciatica (Lumbar region)
0.693 0.307 0.000
C25.0 Head of pancreas
0.693 0.307 0.000
Z85.0 Personal history of malignant neoplasm of digestive organs
0.693 0.307 0.000
Z85.9 Personal history of malignant neoplasm, unspecified
0.693 0.307 0.000
S81 Open wound of lower leg
0.693 0.307 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.692 0.307 0.000
Z38 Liveborn infants according to place of birth
0.692 0.308 0.000
Z31 Procreative management
0.692 0.308 0.000
Z87 Personal history of other diseases and conditions
0.692 0.308 0.000
Z98.0 Intestinal bypass and anastomosis status
0.692 0.308 0.000
J94 Other pleural conditions
0.691 0.309 0.000
S88 Traumatic amputation of lower leg
0.690 0.310 0.000
S87 Crushing injury of lower leg
0.690 0.310 0.000
S86 Injury of muscle and tendon at lower leg level
0.690 0.310 0.000
S85 Injury of blood vessels at lower leg level
0.690 0.310 0.000
S84 Injury of nerves at lower leg level
0.690 0.310 0.000
I36 Nonrheumatic tricuspid valve disorders
0.690 0.310 0.000
R87 Abnormal findings in specimens from female genital organs
0.689 0.311 0.000
S40-S49 Injuries to the shoulder and upper arm
0.689 0.311 0.000
S05.8 Other injuries of eye and orbit
0.688 0.312 0.000
G40-G47 Episodic and paroxysmal disorders
0.688 0.312 0.000
Z53 Persons encountering health services for specifie procedures, not carried out
0.686 0.314 0.000
M54.2 Cervicalgia
0.686 0.314 0.000
Y35-Y36 Legal intervention and operations of war
0.686 0.314 0.000
Y10-Y34 Event of undetermined intent
0.686 0.314 0.000
Y00-Y09 Assault
0.686 0.314 0.000
X85-X99 Assault
0.686 0.314 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.686 0.314 0.000
X50-X57 Overexertion, travel and privation
0.686 0.314 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.686 0.314 0.000
X30-X39 Exposure to forces of nature
0.686 0.314 0.000
X10-X19 Contact with heat and hot substances
0.686 0.314 0.000
X00-X09 Exposure to smoke, fire and flames
0.686 0.314 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.686 0.314 0.000
W75-W84 Other accidental threats to breathing
0.686 0.314 0.000
W65-W74 Accidental drowning and submersion
0.686 0.314 0.000
W50-W64 Exposure to animate mechanical forces
0.686 0.314 0.000
V98-V99 Other and unspecified transport accidents
0.686 0.314 0.000
V95-V97 Air and space transport accidents
0.686 0.314 0.000
V90-V94 Water transport accidents
0.686 0.314 0.000
V70-V79 Bus occupant injured in transport accident
0.686 0.314 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.686 0.314 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.686 0.314 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.686 0.314 0.000
V01-V09 Pedestrian injured in transport accident
0.686 0.314 0.000
I44.1 Atrioventricular block, second degree
0.685 0.315 0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure
0.685 0.315 0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft
0.685 0.315 0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis
0.685 0.315 0.000
T82.4 Mechanical complication of vascular dialysis catheter
0.685 0.315 0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.685 0.315 0.000
Z85.6 Personal history of leukaemia
0.684 0.316 0.000
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)
0.684 0.316 0.000
Z08.0 Follow-up examination after surgery for malignant neoplasm
0.684 0.316 0.000
S61.9 Open wound of wrist and hand, part unspecified
0.683 0.317 0.000
Z37 Outcome of delivery
0.683 0.317 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.682 0.318 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.682 0.318 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.682 0.318 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.682 0.318 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.682 0.318 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.682 0.318 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.682 0.318 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.682 0.318 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.682 0.318 0.000
T36 Poisoning by systemic antibiotics
0.682 0.318 0.000
J40 Bronchitis, not specified as acute or chronic
0.682 0.318 0.000
S62 Fracture at wrist and hand level
0.680 0.320 0.000
M54.16 Radiculopathy (Lumbar region)
0.680 0.320 0.000
S00.0 Superficial injury of scalp
0.680 0.320 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.679 0.321 0.000
C63 Malignant neoplasm of other and unspecified male genital organs
0.679 0.321 0.000
C60 Malignant neoplasm of penis
0.679 0.321 0.000
Q05 Spina bifida
0.679 0.321 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.679 0.321 0.000
B15-B19 Viral hepatitis
0.678 0.321 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.678 0.322 0.000
G70-G73 Diseases of myoneural junction and muscle
0.678 0.322 0.000
Z40 Prophylactic surgery
0.678 0.322 0.000
B99-B99 Other infectious diseases
0.678 0.322 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.678 0.322 0.000
B65-B83 Helminthiases
0.678 0.322 0.000
B50-B64 Protozoal diseases
0.678 0.322 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.678 0.322 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.678 0.322 0.000
A75-A79 Rickettsioses
0.678 0.322 0.000
A70-A74 Other diseases caused by chlamydiae
0.678 0.322 0.000
A65-A69 Other spirochaetal diseases
0.678 0.322 0.000
A20-A28 Certain zoonotic bacterial diseases
0.678 0.322 0.000
A15-A19 Tuberculosis
0.678 0.322 0.000
S09.8 Other specified injuries of head
0.678 0.322 0.000
T85.9 Unspecified complication of internal prosthetic device, implant and graft
0.678 0.322 0.000
T85.1 Mechanical complication of implanted electronic stimulator of nervous system
0.678 0.322 0.000
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt
0.678 0.322 0.000
W20-W49 Exposure to inanimate mechanical forces
0.678 0.322 0.000
H65 Nonsuppurative otitis media
0.677 0.323 0.000
Z00.5 Examination of potential donor of organ and tissue
0.677 0.323 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.677 0.323 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.677 0.323 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.677 0.323 0.000
Q35-Q37 Cleft lip and cleft palate
0.677 0.323 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.677 0.323 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.677 0.323 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.676 0.324 0.000
S67 Crushing injury of wrist and hand
0.676 0.324 0.000
S08 Traumatic amputation of part of head
0.676 0.324 0.000
S07 Crushing injury of head
0.676 0.324 0.000
S04 Injury of cranial nerves
0.676 0.324 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.676 0.324 0.000
Z51.9 Medical care, unspecified
0.676 0.324 0.000
Z51.6 Desensitisation to allergens
0.676 0.324 0.000
H55-H59 Other disorders of eye and adnexa
0.675 0.324 0.000
Y42.5 Other oestrogens and progestogens
0.675 0.325 0.000
A04 Other bacterial intestinal infections
0.675 0.325 0.000
I63.8 Other cerebral infarction
0.675 0.325 0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.675 0.325 0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.675 0.325 0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.675 0.325 0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.675 0.325 0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.675 0.325 0.000
Z52 Donors of organs and tissues
0.675 0.325 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.675 0.325 0.000
Z13.6 Special screening examination for cardiovascular disorders
0.675 0.325 0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.674 0.325 0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.674 0.325 0.000
I69.1 Sequelae of intracerebral haemorrhage
0.674 0.325 0.000
I69.0 Sequelae of subarachnoid haemorrhage
0.674 0.325 0.000
I35.9 Aortic valve disorder, unspecified
0.673 0.327 0.000
Y83.4 Other reconstructive surgery
0.673 0.327 0.000
I52 Other heart disorders in diseases classified elsewhere
0.673 0.327 0.000
I48 Atrial fibrillation and flutter
0.673 0.327 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.673 0.327 0.000
I41 Myocarditis in diseases classified elsewhere
0.673 0.327 0.000
I40 Acute myocarditis
0.673 0.327 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.673 0.327 0.000
I37 Pulmonary valve disorders
0.673 0.327 0.000
I32 Pericarditis in diseases classified elsewhere
0.673 0.327 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.672 0.327 0.000
M66 Spontaneous rupture of synovium and tendon
0.672 0.327 0.000
K83 Other diseases of biliary tract
0.672 0.328 0.000
Z04 Examination and observation for other reasons
0.672 0.328 0.000
K82 Other diseases of gallbladder
0.671 0.329 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.670 0.330 0.000
S20 Superficial injury of thorax
0.669 0.331 0.000
Z88.1 Personal history of allergy to other antibiotic agents
0.669 0.331 0.000
G45.9 Transient cerebral ischaemic attack, unspecified
0.669 0.331 0.000
Z47.9 Orthopaedic follow-up care, unspecified
0.668 0.331 0.000
J92.9 Pleural plaque without asbestos
0.668 0.332 0.000
R50-R69 General symptoms and signs
0.668 0.332 0.000
I33.0 Acute and subacute infective endocarditis
0.667 0.333 0.000
I87 Other disorders of veins
0.667 0.333 0.000
M67.8 Other specified disorders of synovium and tendon
0.666 0.334 0.000
R42 Dizziness and giddiness
0.666 0.334 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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