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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs116186330
log Bayes Factor = 20.4189
Chromosome 3   position 38,631,145  (GRCh37) Explore rs116186330 on Ensembl!
Variant rs116186330 is part of Cluster X0077

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.999 0.001 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.999 0.001 0.000
Chapter II Neoplasms
0.999 0.001 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.997 0.003 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.996 0.004 0.000
Z92 Personal history of medical treatment
0.994 0.006 0.000
E70-E90 Metabolic disorders
0.992 0.008 0.000
I21 Acute myocardial infarction
0.990 0.010 0.000
Chapter VI Diseases of the nervous system
0.988 0.012 0.000
Z51 Other medical care
0.986 0.014 0.000
I25 Chronic ischaemic heart disease
0.985 0.015 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.984 0.016 0.000
C15-C26 Malignant neoplasms of digestive organs
0.983 0.017 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.980 0.020 0.000
M45-M49 Spondylopathies
0.979 0.021 0.000
S00-S09 Injuries to the head
0.977 0.023 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.975 0.025 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.969 0.031 0.000
Z45 Adjustment and management of implanted device
0.966 0.034 0.000
Chapter X Diseases of the respiratory system
0.966 0.034 0.000
J30-J39 Other diseases of upper respiratory tract
0.965 0.035 0.000
R07 Pain in throat and chest
0.961 0.039 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.957 0.043 0.000
Z92.6 Personal history of chemotherapy for neoplastic disease
0.953 0.047 0.000
Chapter XX External causes of morbidity and mortality
0.952 0.048 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.949 0.051 0.000
M15-M19 Arthrosis
0.948 0.052 0.000
M47 Spondylosis
0.946 0.054 0.000
Z92.2 Personal history of long-term (current) use of other medicaments
0.945 0.055 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.944 0.056 0.000
S00 Superficial injury of head
0.942 0.058 0.000
E83 Disorders of mineral metabolism
0.940 0.060 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.939 0.061 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.938 0.062 0.000
M16 Coxarthrosis [arthrosis of hip]
0.936 0.064 0.000
I10-I15 Hypertensive diseases
0.936 0.064 0.000
R00 Abnormalities of heart beat
0.936 0.064 0.000
I22 Subsequent myocardial infarction
0.934 0.066 0.000
E87.5 Hyperkalaemia
0.934 0.066 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.929 0.071 0.000
Z51.4 Preparatory care for treatment, not elsewhere classified
0.926 0.074 0.000
I21.9 Acute myocardial infarction, unspecified
0.924 0.076 0.000
M80-M85 Disorders of bone density and structure
0.923 0.077 0.000
M50-M54 Other dorsopathies
0.923 0.077 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.921 0.079 0.000
G40-G47 Episodic and paroxysmal disorders
0.920 0.080 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.918 0.082 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.918 0.082 0.000
Chapter I Certain infectious and parasitic diseases
0.915 0.085 0.000
E10-E14 Diabetes mellitus
0.908 0.092 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.908 0.092 0.000
R07.3 Other chest pain
0.906 0.094 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.905 0.095 0.000
M16.9 Coxarthrosis, unspecified
0.904 0.096 0.000
Chapter V Mental and behavioural disorders
0.904 0.096 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.903 0.097 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.903 0.097 0.000
C44 Other malignant neoplasms of skin
0.901 0.099 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.899 0.101 0.000
J32 Chronic sinusitis
0.898 0.102 0.000
M47.8 Other spondylosis
0.895 0.105 0.000
I10 Essential (primary) hypertension
0.892 0.108 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.888 0.112 0.000
I20 Angina pectoris
0.882 0.118 0.000
R00.1 Bradycardia, unspecified
0.878 0.122 0.000
Z80 Family history of malignant neoplasm
0.877 0.123 0.000
M05-M14 Inflammatory polyarthropathies
0.877 0.123 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.877 0.123 0.000
M51 Other intervertebral disk disorders
0.875 0.125 0.000
Z45.8 Adjustment and management of other implanted devices
0.873 0.127 0.000
R50-R69 General symptoms and signs
0.872 0.128 0.000
J34 Other disorders of nose and nasal sinuses
0.871 0.129 0.000
G90-G99 Other disorders of the nervous system
0.871 0.129 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.870 0.130 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.869 0.131 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.869 0.131 0.000
Z51.8 Other specified medical care
0.868 0.132 0.000
Z93 Artificial opening status
0.868 0.132 0.000
S01 Open wound of head
0.865 0.135 0.000
F30-F39 Mood [affective] disorders
0.859 0.141 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.859 0.141 0.000
Z92.4 Personal history of major surgery, not elsewhere classified
0.858 0.142 0.000
S00.0 Superficial injury of scalp
0.853 0.147 0.000
E14 Unspecified diabetes mellitus
0.853 0.147 0.000
Z45.2 Adjustment and management of vascular access device
0.852 0.148 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.852 0.148 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.851 0.149 0.000
R00.2 Palpitations
0.850 0.150 0.000
C16 Malignant neoplasm of stomach
0.849 0.151 0.000
S60-S69 Injuries to the wrist and hand
0.849 0.151 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.848 0.152 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
0.845 0.155 0.000
J33 Nasal polyp
0.845 0.155 0.000
E83.5 Disorders of calcium metabolism
0.845 0.155 0.000
M47.82 Other spondylosis (Cervical region)
0.843 0.157 0.000
Z51.1 Chemotherapy session for neoplasm
0.842 0.158 0.000
S00.1 Contusion of eyelid and periocular area
0.842 0.158 0.000
R07.4 Chest pain, unspecified
0.840 0.160 0.000
M16.0 Primary coxarthrosis, bilateral
0.836 0.164 0.000
M48 Other spondylopathies
0.834 0.166 0.000
Z42 Follow-up care involving plastic surgery
0.831 0.169 0.000
E83.1 Disorders of iron metabolism
0.830 0.170 0.000
Z80.3 Family history of malignant neoplasm of breast
0.828 0.172 0.000
Z94 Transplanted organ and tissue status
0.827 0.173 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.826 0.174 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.824 0.175 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.824 0.176 0.000
Z51.3 Blood transfusion without reported diagnosis
0.823 0.177 0.000
C15 Malignant neoplasm of oesophagus
0.823 0.177 0.000
M47.9 Spondylosis, unspecified
0.822 0.178 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.821 0.179 0.000
Chapter XXII Codes for special purposes
0.820 0.179 0.000
T90 Sequelae of injuries of head
0.820 0.180 0.000
R07.2 Precordial pain
0.819 0.181 0.000
S40-S49 Injuries to the shoulder and upper arm
0.817 0.183 0.000
E87.0 Hyperosmolality and hypernatraemia
0.817 0.183 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.816 0.184 0.000
C78.0 Secondary malignant neoplasm of lung
0.815 0.185 0.000
Q60-Q64 Congenital malformations of the urinary system
0.814 0.186 0.000
C44.3 Skin of other and unspecified parts of face
0.813 0.187 0.000
Z95.1 Presence of aortocoronary bypass graft
0.813 0.187 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.810 0.190 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.809 0.191 0.000
Z98 Other postsurgical states
0.807 0.193 0.000
Y43 Primarily systemic agents
0.807 0.193 0.000
J34.2 Deviated nasal septum
0.806 0.194 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.806 0.194 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.804 0.195 0.000
Z90.4 Acquired absence of other parts of digestive tract
0.804 0.196 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.804 0.196 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.804 0.196 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.801 0.199 0.000
M91-M94 Chondropathies
0.800 0.200 0.000
Z51.0 Radiotherapy session
0.800 0.200 0.000
E14.9 Without complications
0.799 0.201 0.000
R03.0 Elevated blood-pressure reading, without diagnosis of hypertension
0.798 0.202 0.000
Z49 Care involving dialysis
0.798 0.202 0.000
C44.7 Skin of lower limb, including hip
0.797 0.203 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.795 0.205 0.000
F32 Depressive episode
0.794 0.206 0.000
J38.3 Other diseases of vocal cords
0.793 0.207 0.000
M51.2 Other specified intervertebral disk displacement
0.793 0.207 0.000
M81 Osteoporosis without pathological fracture
0.792 0.208 0.000
G20-G26 Extrapyramidal and movement disorders
0.791 0.209 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.790 0.210 0.000
Z90.6 Acquired absence of other parts of urinary tract
0.787 0.213 0.000
I95 Hypotension
0.786 0.214 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.784 0.216 0.000
R55 Syncope and collapse
0.783 0.217 0.000
Z43 Attention to artificial openings
0.782 0.218 0.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system
0.782 0.218 0.000
Z89 Acquired absence of limb
0.781 0.219 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.781 0.219 0.000
J32.0 Chronic maxillary sinusitis
0.781 0.219 0.000
E87.6 Hypokalaemia
0.780 0.220 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.780 0.220 0.000
W00-W19 Falls
0.779 0.221 0.000
C78.2 Secondary malignant neoplasm of pleura
0.778 0.222 0.000
C20 Malignant neoplasm of rectum
0.775 0.225 0.000
C80 Malignant neoplasm without specification of site
0.775 0.225 0.000
B35-B49 Mycoses
0.775 0.225 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.775 0.225 0.000
G30-G32 Other degenerative diseases of the nervous system
0.773 0.227 0.000
I22.0 Subsequent myocardial infarction of anterior wall
0.773 0.227 0.000
S01.8 Open wound of other parts of head
0.772 0.228 0.000
M40-M43 Deforming dorsopathies
0.770 0.230 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.769 0.231 0.000
G40 Epilepsy
0.767 0.233 0.000
C78.7 Secondary malignant neoplasm of liver
0.767 0.233 0.000
Z45.1 Adjustment and management of infusion pump
0.767 0.233 0.000
S90-S99 Injuries to the ankle and foot
0.766 0.234 0.000
M16.7 Other secondary coxarthrosis
0.765 0.235 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.763 0.237 0.000
I22.8 Subsequent myocardial infarction of other sites
0.761 0.239 0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.761 0.239 0.000
M86-M90 Other osteopathies
0.761 0.239 0.000
M10 Gout
0.761 0.239 0.000
R52 Pain, not elsewhere classified
0.761 0.239 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.761 0.239 0.000
Z46 Fitting and adjustment of other devices
0.761 0.239 0.000
F31 Bipolar affective disorder
0.758 0.242 0.000
Q80-Q89 Other congenital malformations
0.758 0.242 0.000
Z52 Donors of organs and tissues
0.758 0.242 0.000
R54 Senility
0.758 0.242 0.000
M84 Disorders of continuity of bone
0.757 0.243 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.756 0.244 0.000
E87.2 Acidosis
0.756 0.244 0.000
M06 Other rheumatoid arthritis
0.754 0.246 0.000
G44 Other headache syndromes
0.754 0.246 0.000
R47-R49 Symptoms and signs involving speech and voice
0.754 0.246 0.000
M45 Ankylosing spondylitis
0.753 0.247 0.000
J33.9 Nasal polyp, unspecified
0.752 0.248 0.000
Z51.5 Palliative care
0.752 0.248 0.000
M80 Osteoporosis with pathological fracture
0.752 0.248 0.000
I80 Phlebitis and thrombophlebitis
0.752 0.248 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.749 0.250 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.749 0.251 0.000
Z45.0 Adjustment and management of cardiac pacemaker
0.749 0.251 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.748 0.252 0.000
C18 Malignant neoplasm of colon
0.748 0.252 0.000
Z96 Presence of other functional implants
0.746 0.254 0.000
A00-A09 Intestinal infectious diseases
0.746 0.254 0.000
S70-S79 Injuries to the hip and thigh
0.745 0.255 0.000
I20.9 Angina pectoris, unspecified
0.745 0.255 0.000
G70-G73 Diseases of myoneural junction and muscle
0.744 0.256 0.000
J35 Chronic diseases of tonsils and adenoids
0.743 0.257 0.000
T66-T78 Other and unspecified effects of external causes
0.742 0.258 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.742 0.258 0.000
Z42.4 Follow-up care involving plastic surgery of lower extremity
0.741 0.258 0.000
S80-S89 Injuries to the knee and lower leg
0.741 0.259 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.740 0.260 0.000
S00.8 Superficial injury of other parts of head
0.740 0.260 0.000
R04 Haemorrhage from respiratory passages
0.740 0.260 0.000
A30-A49 Other bacterial diseases
0.739 0.261 0.000
C25 Malignant neoplasm of pancreas
0.739 0.261 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.739 0.261 0.000
C44.6 Skin of upper limb, including shoulder
0.739 0.261 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.739 0.261 0.000
Z90.1 Acquired absence of breast(s)
0.738 0.262 0.000
I20.8 Other forms of angina pectoris
0.738 0.262 0.000
C44.0 Skin of lip
0.738 0.262 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.738 0.262 0.000
V80-V89 Other land transport accidents
0.733 0.266 0.000
M65-M68 Disorders of synovium and tendon
0.733 0.267 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.733 0.267 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.733 0.267 0.000
C91 Lymphoid leukaemia
0.732 0.268 0.000
Chapter VIII Diseases of the ear and mastoid process
0.732 0.268 0.000
R63 Symptoms and signs concerning food and fluid intake
0.732 0.268 0.000
J32.4 Chronic pansinusitis
0.731 0.269 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.731 0.269 0.000
M48.0 Spinal stenosis
0.731 0.269 0.000
B95-B98 Bacterial, viral and other infectious agents
0.730 0.270 0.000
M47.92 Spondylosis, unspecified (Cervical region)
0.729 0.271 0.000
I21.4 Acute subendocardial myocardial infarction
0.728 0.271 0.000
G43 Migraine
0.728 0.272 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.727 0.273 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.727 0.273 0.000
T93 Sequelae of injuries of lower limb
0.727 0.273 0.000
C16.9 Stomach, unspecified
0.727 0.273 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.727 0.273 0.000
J34.3 Hypertrophy of nasal turbinates
0.726 0.274 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.725 0.275 0.000
Z95.0 Presence of cardiac pacemaker
0.725 0.275 0.000
E86 Volume depletion
0.724 0.276 0.000
J39 Other diseases of upper respiratory tract
0.724 0.276 0.000
W20-W49 Exposure to inanimate mechanical forces
0.723 0.277 0.000
M18 Arthrosis of first carpometacarpal joint
0.723 0.277 0.000
M50 Cervical disk disorders
0.721 0.279 0.000
Q61 Cystic kidney disease
0.720 0.280 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.720 0.280 0.000
C50-C50 Malignant neoplasm of breast
0.720 0.280 0.000
D37.5 Rectum
0.719 0.281 0.000
V20-V29 Motorcycle rider injured in transport accident
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
I23 Certain current complications following acute myocardial infarction
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
T79-T79 Certain early complications of trauma
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S10-S19 Injuries to the neck
0.717 0.283 0.000
Z97 Presence of other devices
0.717 0.283 0.000
Z84 Family history of other conditions
0.717 0.283 0.000
Z81 Family history of mental and behavioural disorders
0.717 0.283 0.000
L60-L75 Disorders of skin appendages
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.716 0.284 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.716 0.284 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.716 0.284 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.716 0.284 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.716 0.284 0.000
I95.9 Hypotension, unspecified
0.716 0.284 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.716 0.284 0.000
Z54 Convalescence
0.715 0.285 0.000
Z44 Fitting and adjustment of external prosthetic device
0.715 0.285 0.000
T90.2 Sequelae of fracture of skull and facial bones
0.714 0.286 0.000
E40-E46 Malnutrition
0.714 0.286 0.000
Z94.0 Kidney transplant status
0.713 0.287 0.000
Z92.9 Personal history of medical treatment, unspecified
0.712 0.287 0.000
Z92.8 Personal history of other medical treatment
0.712 0.287 0.000
Z92.5 Personal history of rehabilitation measures
0.712 0.287 0.000
Z92.0 Personal history of contraception
0.712 0.287 0.000
G95 Other diseases of spinal cord
0.712 0.288 0.000
E88 Other metabolic disorders
0.711 0.289 0.000
E85 Amyloidosis
0.711 0.289 0.000
E84 Cystic fibrosis
0.711 0.289 0.000
E79 Disorders of purine and pyrimidine metabolism
0.711 0.289 0.000
E77 Disorders of glycoprotein metabolism
0.711 0.289 0.000
E76 Disorders of glycosaminoglycan metabolism
0.711 0.289 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.711 0.289 0.000
E74 Other disorders of carbohydrate metabolism
0.711 0.289 0.000
E73 Lactose intolerance
0.711 0.289 0.000
E72 Other disorders of amino-acid metabolism
0.711 0.289 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.711 0.289 0.000
E70 Disorders of aromatic amino-acid metabolism
0.711 0.289 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.711 0.289 0.000
M51.8 Other specified intervertebral disk disorders
0.711 0.289 0.000
Z92.3 Personal history of irradiation
0.711 0.289 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.710 0.290 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.710 0.290 0.000
Z90.5 Acquired absence of kidney
0.710 0.290 0.000
R59 Enlarged lymph nodes
0.709 0.291 0.000
Y52 Agents primarily affecting the cardiovascular system
0.709 0.291 0.000
S50-S59 Injuries to the elbow and forearm
0.708 0.292 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.708 0.292 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.708 0.292 0.000
T92 Sequelae of injuries of upper limb
0.708 0.292 0.000
J32.9 Chronic sinusitis, unspecified
0.708 0.292 0.000
Z93.3 Colostomy status
0.707 0.293 0.000
Z51.9 Medical care, unspecified
0.707 0.293 0.000
Z51.6 Desensitisation to allergens
0.707 0.293 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.707 0.293 0.000
I25.6 Silent myocardial ischaemia
0.706 0.294 0.000
I25.5 Ischaemic cardiomyopathy
0.706 0.294 0.000
I25.4 Coronary artery aneurysm
0.706 0.294 0.000
I25.3 Aneurysm of heart
0.706 0.294 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.706 0.294 0.000
Z99.3 Dependence on wheelchair
0.706 0.294 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.705 0.294 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.704 0.295 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.704 0.295 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.704 0.295 0.000
C21 Malignant neoplasm of anus and anal canal
0.704 0.295 0.000
C17 Malignant neoplasm of small intestine
0.704 0.295 0.000
C23 Malignant neoplasm of gallbladder
0.704 0.295 0.000
S20-S29 Injuries to the thorax
0.704 0.296 0.000
S64 Injury of nerves at wrist and hand level
0.704 0.296 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.704 0.296 0.000
M49 Spondylopathies in diseases classified elsewhere
0.702 0.298 0.000
R50 Fever of unknown origin
0.702 0.298 0.000
Z95.3 Presence of xenogenic heart valve
0.702 0.298 0.000
S08 Traumatic amputation of part of head
0.701 0.299 0.000
S07 Crushing injury of head
0.701 0.299 0.000
S05 Injury of eye and orbit
0.701 0.299 0.000
S04 Injury of cranial nerves
0.701 0.299 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.701 0.299 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.700 0.300 0.000
S02 Fracture of skull and facial bones
0.699 0.301 0.000
S06 Intracranial injury
0.699 0.301 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.699 0.301 0.000
E87.4 Mixed disorder of acid-base balance
0.699 0.301 0.000
E87.3 Alkalosis
0.699 0.301 0.000
J38.1 Polyp of vocal cord and larynx
0.699 0.301 0.000
Z80.1 Family history of malignant neoplasm of trachea, bronchus and lung
0.698 0.302 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.698 0.302 0.000
Z90.0 Acquired absence of part of head and neck
0.697 0.303 0.000
Z93.6 Other artificial openings of urinary tract status
0.696 0.304 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.696 0.304 0.000
C44.1 Skin of eyelid, including canthus
0.696 0.304 0.000
E83.3 Disorders of phosphorus metabolism
0.696 0.304 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.695 0.305 0.000
I22.1 Subsequent myocardial infarction of inferior wall
0.694 0.306 0.000
Q50-Q56 Congenital malformations of genital organs
0.694 0.306 0.000
Z53 Persons encountering health services for specifie procedures, not carried out
0.694 0.306 0.000
D60-D64 Aplastic and other anaemias
0.694 0.306 0.000
Z90.2 Acquired absence of lung [part of]
0.693 0.307 0.000
D37.9 Digestive organ, unspecified
0.693 0.307 0.000
E78.5 Hyperlipidaemia, unspecified
0.693 0.307 0.000
Z45.9 Adjustment and management of unspecified implanted device
0.693 0.307 0.000
Z45.3 Adjustment and management of implanted hearing device
0.693 0.307 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.693 0.307 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.693 0.307 0.000
E20-E35 Disorders of other endocrine glands
0.692 0.307 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.692 0.308 0.000
J37 Chronic laryngitis and laryngotracheitis
0.692 0.308 0.000
J00-J06 Acute upper respiratory infections
0.692 0.308 0.000
Y43.4 Immunosuppressive agents
0.691 0.309 0.000
Z99.8 Dependence on other enabling machines and devices
0.691 0.309 0.000
F99-F99 Unspecified mental disorder
0.689 0.310 0.000
R07.1 Chest pain on breathing
0.689 0.311 0.000
J30 Vasomotor and allergic rhinitis
0.689 0.311 0.000
M46 Other inflammatory spondylopathies
0.688 0.312 0.000
C83.3 Large cell (diffuse)
0.688 0.312 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.687 0.313 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.687 0.313 0.000
F32.2 Severe depressive episode without psychotic symptoms
0.687 0.313 0.000
J36 Peritonsillar abscess
0.686 0.313 0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.686 0.314 0.000
M47.89 Other spondylosis (Site unspecified)
0.686 0.314 0.000
M47.87 Other spondylosis (Lumbosacral region)
0.686 0.314 0.000
D00-D09 In situ neoplasms
0.686 0.314 0.000
E87.7 Fluid overload
0.686 0.314 0.000
J32.8 Other chronic sinusitis
0.686 0.314 0.000
M51.9 Intervertebral disk disorder, unspecified
0.685 0.314 0.000
X60-X84 Intentional self-harm
0.684 0.316 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.684 0.316 0.000
Z95.2 Presence of prosthetic heart valve
0.683 0.317 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.683 0.317 0.000
Y35-Y36 Legal intervention and operations of war
0.683 0.317 0.000
Y10-Y34 Event of undetermined intent
0.683 0.317 0.000
Y00-Y09 Assault
0.683 0.317 0.000
X85-X99 Assault
0.683 0.317 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.683 0.317 0.000
X50-X57 Overexertion, travel and privation
0.683 0.317 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.683 0.317 0.000
X30-X39 Exposure to forces of nature
0.683 0.317 0.000
X20-X29 Contact with venomous animals and plants
0.683 0.317 0.000
X10-X19 Contact with heat and hot substances
0.683 0.317 0.000
X00-X09 Exposure to smoke, fire and flames
0.683 0.317 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.683 0.317 0.000
W75-W84 Other accidental threats to breathing
0.683 0.317 0.000
W65-W74 Accidental drowning and submersion
0.683 0.317 0.000
W50-W64 Exposure to animate mechanical forces
0.683 0.317 0.000
V98-V99 Other and unspecified transport accidents
0.683 0.317 0.000
V95-V97 Air and space transport accidents
0.683 0.317 0.000
V90-V94 Water transport accidents
0.683 0.317 0.000
V70-V79 Bus occupant injured in transport accident
0.683 0.317 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.683 0.317 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.683 0.317 0.000
V40-V49 Car occupant injured in transport accident
0.683 0.317 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.683 0.317 0.000
V01-V09 Pedestrian injured in transport accident
0.683 0.317 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.682 0.318 0.000
R07.0 Pain in throat
0.682 0.318 0.000
S01.2 Open wound of nose
0.681 0.319 0.000
D45 Polycythaemia vera
0.681 0.319 0.000
M81.9 Osteoporosis, unspecified
0.680 0.319 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.680 0.319 0.000
M15 Polyarthrosis
0.680 0.320 0.000
E50-E64 Other nutritional deficiencies
0.680 0.320 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.679 0.321 0.000
F32.9 Depressive episode, unspecified
0.679 0.321 0.000
M47.1 Other spondylosis with myelopathy
0.678 0.322 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.678 0.322 0.000
M10.9 Gout, unspecified
0.678 0.322 0.000
E14.3 With ophthalmic complications
0.677 0.323 0.000
M47.2 Other spondylosis with radiculopathy
0.677 0.323 0.000
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities
0.677 0.323 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.677 0.323 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.677 0.323 0.000
Q35-Q37 Cleft lip and cleft palate
0.677 0.323 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.677 0.323 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.677 0.323 0.000
Q00-Q07 Congenital malformations of the nervous system
0.677 0.323 0.000
Z53.9 Procedure not carried out, unspecified reason
0.676 0.324 0.000
G93 Other disorders of brain
0.676 0.324 0.000
S09 Other and unspecified injuries of head
0.676 0.324 0.000
S00.7 Multiple superficial injuries of head
0.675 0.325 0.000
S00.5 Superficial injury of lip and oral cavity
0.675 0.325 0.000
S00.4 Superficial injury of ear
0.675 0.325 0.000
S00.3 Superficial injury of nose
0.675 0.325 0.000
S00.2 Other superficial injuries of eyelid and periocular area
0.675 0.325 0.000
Z82.0 Family history of epilepsy and other diseases of the nervous system
0.675 0.325 0.000
Z80.4 Family history of malignant neoplasm of genital organs
0.675 0.325 0.000
E83.9 Disorder of mineral metabolism, unspecified
0.674 0.326 0.000
E83.8 Other disorders of mineral metabolism
0.674 0.326 0.000
E83.2 Disorders of zinc metabolism
0.674 0.326 0.000
E83.0 Disorders of copper metabolism
0.674 0.326 0.000
M05 Seropositive rheumatoid arthritis
0.674 0.326 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.674 0.326 0.000
J95-J99 Other diseases of the respiratory system
0.674 0.326 0.000
C81 Hodgkin's disease
0.673 0.327 0.000
J38.0 Paralysis of vocal cords and larynx
0.672 0.328 0.000
M16.6 Other secondary coxarthrosis, bilateral
0.671 0.329 0.000
M16.5 Other posttraumatic coxarthrosis
0.671 0.329 0.000
M16.4 Posttraumatic coxarthrosis, bilateral
0.671 0.329 0.000
M16.3 Other dysplastic coxarthrosis
0.671 0.329 0.000
M16.2 Coxarthrosis resulting from dysplasia, bilateral
0.671 0.329 0.000
S00.9 Superficial injury of head, part unspecified
0.671 0.329 0.000
I15 Secondary hypertension
0.671 0.329 0.000
I13 Hypertensive heart and renal disease
0.671 0.329 0.000
I11 Hypertensive heart disease
0.671 0.329 0.000
R00.8 Other and unspecified abnormalities of heart beat
0.671 0.329 0.000
E78.2 Mixed hyperlipidaemia
0.670 0.329 0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy
0.670 0.330 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.669 0.330 0.000
C15.5 Lower third of oesophagus
0.669 0.331 0.000
G55.1 Nerve root and plexus compressions in intervertebral disk disorders
0.669 0.331 0.000
Z86 Personal history of certain other diseases
0.669 0.331 0.000
Z96.0 Presence of urogenital implants
0.668 0.332 0.000
R06 Abnormalities of breathing
0.668 0.332 0.000
C92 Myeloid leukaemia
0.668 0.332 0.000
Z99.2 Dependence on renal dialysis
0.667 0.333 0.000
E83.4 Disorders of magnesium metabolism
0.666 0.334 0.000
T87 Complications peculiar to reattachment and amputation
0.666 0.334 0.000
T86 Failure and rejection of transplanted organs and tissues
0.666 0.334 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.666 0.334 0.000
T90.5 Sequelae of intracranial injury
0.666 0.334 0.000
J31.0 Chronic rhinitis
0.665 0.335 0.000
R73 Elevated blood glucose level
0.665 0.335 0.000
Z82.3 Family history of stroke
0.664 0.336 0.000
E10 Insulin-dependent diabetes mellitus
0.664 0.336 0.000
T82.1 Mechanical complication of cardiac electronic device
0.664 0.336 0.000
Z50 Care involving use of rehabilitation procedures
0.664 0.336 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.663 0.337 0.000
C16.0 Cardia
0.662 0.337 0.000
Y43.3 Other antineoplastic drugs
0.662 0.337 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.662 0.337 0.000
M85 Other disorders of bone density and structure
0.662 0.338 0.000
M83 Adult osteomalacia
0.662 0.338 0.000
M82 Osteoporosis in diseases classified elsewhere
0.662 0.338 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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