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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs116332762
log Bayes Factor = 17.3941
Chromosome 2   position 108,184,621  (GRCh37) Explore rs116332762 on Ensembl!
Variant rs116332762 is part of Cluster X0220

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
Z72 Problems related to lifestyle
1.000 0.000 0.000
Z72.0 Tobacco use
1.000 0.000 0.000
M45-M49 Spondylopathies
1.000 0.000 0.000
Chapter XV Pregnancy, childbirth and the puerperium
1.000 0.000 0.000
Z70-Z76 Persons encountering health services in other circumstances
1.000 0.000 0.000
Chapter X Diseases of the respiratory system
1.000 0.000 0.000
J40-J47 Chronic lower respiratory diseases
0.999 0.001 0.000
J44 Other chronic obstructive pulmonary disease
0.999 0.001 0.000
M47 Spondylosis
0.999 0.001 0.000
M47.8 Other spondylosis
0.998 0.002 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.997 0.003 0.000
O60-O75 Complications of labour and delivery
0.996 0.004 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.993 0.007 0.000
M47.82 Other spondylosis (Cervical region)
0.993 0.007 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.993 0.007 0.000
R07.2 Precordial pain
0.991 0.009 0.000
M70-M79 Other soft tissue disorders
0.990 0.010 0.000
R07 Pain in throat and chest
0.990 0.010 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.990 0.010 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.990 0.010 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.989 0.011 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.983 0.017 0.000
I60-I69 Cerebrovascular diseases
0.981 0.019 0.000
Chapter IX Diseases of the circulatory system
0.980 0.020 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.973 0.027 0.000
Z08.9 Follow-up examination after unspecified treatment for malignant neoplasm
0.969 0.031 0.000
Chapter V Mental and behavioural disorders
0.963 0.037 0.000
I63 Cerebral infarction
0.962 0.038 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.962 0.038 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.960 0.040 0.000
J43 Emphysema
0.958 0.042 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.956 0.044 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.956 0.044 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.952 0.048 0.000
Chapter VI Diseases of the nervous system
0.950 0.050 0.000
R07.3 Other chest pain
0.948 0.052 0.000
Z13 Special screening examination for other diseases and disorders
0.944 0.056 0.000
I63.9 Cerebral infarction, unspecified
0.941 0.059 0.000
M75 Shoulder lesions
0.939 0.061 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.936 0.064 0.000
Chapter XX External causes of morbidity and mortality
0.935 0.065 0.000
F41 Other anxiety disorders
0.935 0.065 0.000
Z13.9 Special screening examination, unspecified
0.931 0.069 0.000
Z08.7 Follow-up examination after combined treatment for malignant neoplasm
0.929 0.071 0.000
J43.9 Emphysema, unspecified
0.929 0.071 0.000
I69 Sequelae of cerebrovascular disease
0.929 0.071 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.921 0.079 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.916 0.084 0.000
M46 Other inflammatory spondylopathies
0.915 0.085 0.000
J60-J70 Lung diseases due to external agents
0.912 0.088 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.911 0.089 0.000
F41.2 Mixed anxiety and depressive disorder
0.907 0.093 0.000
M79.6 Pain in limb
0.907 0.093 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.904 0.096 0.000
O63 Long labour
0.897 0.103 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.894 0.106 0.000
M75.1 Rotator cuff syndrome
0.892 0.108 0.000
Z72.1 Alcohol use
0.887 0.113 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.887 0.113 0.000
O48 Prolonged pregnancy
0.883 0.117 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.880 0.120 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.880 0.120 0.000
O36 Maternal care for other known or suspected foetal problems
0.871 0.129 0.000
Z08.2 Follow-up examination after chemotherapy for malignant neoplasm
0.871 0.129 0.000
M79.1 Myalgia
0.869 0.130 0.000
M47.9 Spondylosis, unspecified
0.868 0.132 0.000
R09.1 Pleurisy
0.868 0.132 0.000
I30-I52 Other forms of heart disease
0.867 0.133 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.865 0.135 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.865 0.135 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.864 0.136 0.000
Chapter VII Diseases of the eye and adnexa
0.857 0.143 0.000
M48 Other spondylopathies
0.856 0.144 0.000
M46.9 Inflammatory spondylopathy, unspecified
0.854 0.146 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.850 0.150 0.000
O40 Polyhydramnios
0.849 0.150 0.000
I45 Other conduction disorders
0.849 0.151 0.000
T92 Sequelae of injuries of upper limb
0.847 0.153 0.000
F41.9 Anxiety disorder, unspecified
0.846 0.154 0.000
J69 Pneumonitis due to solids and liquids
0.843 0.157 0.000
S90-S99 Injuries to the ankle and foot
0.842 0.158 0.000
O69.1 Labour and delivery complicated by cord around neck, with compression
0.842 0.158 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.840 0.160 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.838 0.162 0.000
O70 Perineal laceration during delivery
0.837 0.163 0.000
M05-M14 Inflammatory polyarthropathies
0.831 0.169 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.831 0.169 0.000
L20-L30 Dermatitis and eczema
0.831 0.169 0.000
M65-M68 Disorders of synovium and tendon
0.829 0.171 0.000
M47.87 Other spondylosis (Lumbosacral region)
0.828 0.172 0.000
G51 Facial nerve disorders
0.828 0.172 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.827 0.173 0.000
M91-M94 Chondropathies
0.826 0.173 0.000
S50-S59 Injuries to the elbow and forearm
0.823 0.177 0.000
R42 Dizziness and giddiness
0.822 0.178 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.822 0.178 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.822 0.178 0.000
R09.0 Asphyxia
0.818 0.182 0.000
L57 Skin changes due to chronic exposure to nonionising radiation
0.818 0.182 0.000
G56 Mononeuropathies of upper limb
0.816 0.184 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.816 0.184 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.816 0.184 0.000
R41.0 Disorientation, unspecified
0.809 0.191 0.000
M47.89 Other spondylosis (Site unspecified)
0.808 0.192 0.000
M20-M25 Other joint disorders
0.808 0.192 0.000
H02 Other disorders of eyelid
0.808 0.192 0.000
I05-I09 Chronic rheumatic heart diseases
0.807 0.193 0.000
M47.86 Other spondylosis (Lumbar region)
0.807 0.193 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.805 0.195 0.000
M79.66 Pain in limb (Lower leg)
0.804 0.196 0.000
M80-M85 Disorders of bone density and structure
0.803 0.196 0.000
G90-G99 Other disorders of the nervous system
0.802 0.198 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.799 0.201 0.000
J84 Other interstitial pulmonary diseases
0.799 0.201 0.000
R47-R49 Symptoms and signs involving speech and voice
0.798 0.202 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.797 0.203 0.000
W00-W19 Falls
0.796 0.204 0.000
I62 Other nontraumatic intracranial haemorrhage
0.795 0.205 0.000
I45.1 Other and unspecified right bundle-branch block
0.795 0.205 0.000
S00-S09 Injuries to the head
0.794 0.206 0.000
J69.0 Pneumonitis due to food and vomit
0.793 0.207 0.000
J42 Unspecified chronic bronchitis
0.793 0.207 0.000
I67 Other cerebrovascular diseases
0.792 0.208 0.000
Z72.2 Drug use
0.791 0.209 0.000
O80-O84 Delivery
0.790 0.210 0.000
O36.8 Maternal care for other specified foetal problems
0.789 0.211 0.000
H04 Disorders of lachrymal system
0.789 0.211 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.787 0.213 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.787 0.213 0.000
I69.3 Sequelae of cerebral infarction
0.786 0.214 0.000
T92.2 Sequelae of fracture at wrist and hand level
0.785 0.215 0.000
O75.8 Other specified complications of labour and delivery
0.784 0.216 0.000
L60-L75 Disorders of skin appendages
0.784 0.216 0.000
M47.96 Spondylosis, unspecified (Lumbar region)
0.782 0.218 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.781 0.219 0.000
M47.2 Other spondylosis with radiculopathy
0.780 0.220 0.000
R01 Cardiac murmurs and other cardiac sounds
0.779 0.221 0.000
O70.0 First degree perineal laceration during delivery
0.779 0.221 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.777 0.223 0.000
M75.5 Bursitis of shoulder
0.776 0.224 0.000
M47.80 Other spondylosis (Multiple sites in spine)
0.774 0.226 0.000
Chapter I Certain infectious and parasitic diseases
0.773 0.227 0.000
O42 Premature rupture of membranes
0.771 0.229 0.000
O41 Other disorders of amniotic fluid and membranes
0.770 0.230 0.000
H55-H59 Other disorders of eye and adnexa
0.770 0.230 0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.770 0.230 0.000
O64.0 Obstructed labour due to incomplete rotation of foetal head
0.769 0.231 0.000
R45 Symptoms and signs involving emotional state
0.768 0.232 0.000
J84.1 Other interstitial pulmonary diseases with fibrosis
0.768 0.232 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.766 0.234 0.000
R94 Abnormal results of function studies
0.763 0.237 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.762 0.238 0.000
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness
0.762 0.238 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.761 0.239 0.000
O73 Retained placenta and membranes, without haemorrhage
0.759 0.241 0.000
O85-O92 Complications predominantly related to the puerperium
0.757 0.243 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.756 0.244 0.000
O63.1 Prolonged second stage (of labour)
0.755 0.245 0.000
M40-M43 Deforming dorsopathies
0.754 0.246 0.000
S40-S49 Injuries to the shoulder and upper arm
0.754 0.246 0.000
M77 Other enthesopathies
0.753 0.247 0.000
M79.68 Pain in limb (Other)
0.753 0.247 0.000
F43 Reaction to severe stress, and adjustment disorders
0.752 0.248 0.000
X60-X84 Intentional self-harm
0.752 0.248 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.752 0.248 0.000
O72 Postpartum haemorrhage
0.749 0.251 0.000
F45 Somatoform disorders
0.745 0.255 0.000
O69.2 Labour and delivery complicated by other cord entanglement
0.745 0.255 0.000
I42 Cardiomyopathy
0.745 0.255 0.000
O61 Failed induction of labour
0.743 0.257 0.000
I69.0 Sequelae of subarachnoid haemorrhage
0.743 0.257 0.000
Z04 Examination and observation for other reasons
0.743 0.257 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.743 0.257 0.000
S32 Fracture of lumbar spine and pelvis
0.742 0.257 0.000
I50 Heart failure
0.741 0.259 0.000
F40 Phobic anxiety disorders
0.740 0.260 0.000
M75.9 Shoulder lesion, unspecified
0.738 0.262 0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.737 0.263 0.000
H04.5 Stenosis and insufficiency of lachrymal passages
0.737 0.263 0.000
M79.60 Pain in limb (Multiple sites)
0.737 0.263 0.000
I45.6 Preexcitation syndrome
0.736 0.264 0.000
O66 Other obstructed labour
0.735 0.265 0.000
G51.0 Bell's palsy
0.735 0.265 0.000
M84 Disorders of continuity of bone
0.734 0.266 0.000
R40 Somnolence, stupor and coma
0.733 0.267 0.000
Z73 Problems related to life-management difficulty
0.732 0.267 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.732 0.268 0.000
O34.2 Maternal care due to uterine scar from previous surgery
0.732 0.268 0.000
M48.0 Spinal stenosis
0.732 0.268 0.000
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes
0.731 0.268 0.000
M86-M90 Other osteopathies
0.731 0.268 0.000
O63.0 Prolonged first stage (of labour)
0.731 0.269 0.000
G56.0 Carpal tunnel syndrome
0.731 0.269 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.730 0.270 0.000
V80-V89 Other land transport accidents
0.730 0.270 0.000
M46.92 Inflammatory spondylopathy, unspecified (Cervical region)
0.729 0.271 0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis
0.729 0.271 0.000
M79.19 Myalgia (Site unspecified)
0.728 0.272 0.000
M79.62 Pain in limb (Upper arm)
0.728 0.272 0.000
L08 Other local infections of skin and subcutaneous tissue
0.726 0.274 0.000
J09-J18 Influenza and pneumonia
0.726 0.274 0.000
Z75 Problems related to medical facilities and other health care
0.725 0.275 0.000
Z76 Persons encountering health services in other circumstances
0.725 0.275 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.724 0.276 0.000
M75.2 Bicipital tendinitis
0.724 0.276 0.000
Y86 Sequelae of other accidents
0.724 0.276 0.000
L57.8 Other skin changes due to chronic exposure to nonionising radiation
0.724 0.276 0.000
M79.11 Myalgia (Shoulder region)
0.723 0.277 0.000
L82 Seborrhoeic keratosis
0.723 0.277 0.000
T79-T79 Certain early complications of trauma
0.723 0.277 0.000
M79.63 Pain in limb (Forearm)
0.722 0.278 0.000
G93 Other disorders of brain
0.721 0.279 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.720 0.280 0.000
S91 Open wound of ankle and foot
0.720 0.280 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.719 0.281 0.000
H02.1 Ectropion of eyelid
0.718 0.282 0.000
M47.1 Other spondylosis with myelopathy
0.718 0.282 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
Z72.9 Problem related to lifestyle, unspecified
0.717 0.283 0.000
Z72.8 Other problems related to lifestyle
0.717 0.283 0.000
Z72.6 Gambling and betting
0.717 0.283 0.000
Z72.5 High-risk sexual behaviour
0.717 0.283 0.000
Z72.4 Inappropriate diet and eating habits
0.717 0.283 0.000
Z72.3 Lack of physical exercise
0.717 0.283 0.000
M49 Spondylopathies in diseases classified elsewhere
0.717 0.283 0.000
Z70 Counselling related to sexual attitude, behaviour and orientation
0.717 0.283 0.000
J41 Simple and mucopurulent chronic bronchitis
0.716 0.283 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.716 0.284 0.000
J20-J22 Other acute lower respiratory infections
0.716 0.284 0.000
M47.88 Other spondylosis (Sacral and sacrococcygeal region)
0.715 0.285 0.000
M47.85 Other spondylosis (Thoracolumbar region)
0.715 0.285 0.000
M47.84 Other spondylosis (Thoracic region)
0.715 0.285 0.000
M47.83 Other spondylosis (Cervicothoracic region)
0.715 0.285 0.000
M47.81 Other spondylosis (Occipito-atlanto-axial region)
0.715 0.285 0.000
O74 Complications of anaesthesia during labour and delivery
0.714 0.286 0.000
O71 Other obstetric trauma
0.714 0.286 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.714 0.286 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.714 0.286 0.000
O60 Preterm delivery
0.714 0.286 0.000
O43 Placental disorders
0.714 0.286 0.000
S01 Open wound of head
0.713 0.287 0.000
Z10 Routine general health check-up of defined subpopulation
0.712 0.288 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.712 0.288 0.000
M76 Enthesopathies of lower limb, excluding foot
0.710 0.290 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.710 0.290 0.000
M71 Other bursopathies
0.710 0.290 0.000
O45 Premature separation of placenta [abruptio placentae]
0.710 0.290 0.000
O44 Placenta praevia
0.710 0.290 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.710 0.290 0.000
O33 Maternal care for known or suspected disproportion
0.710 0.290 0.000
O31 Complications specific to multiple gestation
0.710 0.290 0.000
Z08.1 Follow-up examination after radiotherapy for malignant neoplasm
0.709 0.290 0.000
O75.7 Vaginal delivery following previous Caesarean section
0.709 0.291 0.000
X20-X29 Contact with venomous animals and plants
0.709 0.291 0.000
F03 Unspecified dementia
0.709 0.291 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.708 0.292 0.000
O30 Multiple gestation
0.708 0.292 0.000
Chapter XXII Codes for special purposes
0.708 0.292 0.000
S70-S79 Injuries to the hip and thigh
0.708 0.292 0.000
M00-M03 Infectious arthropathies
0.707 0.293 0.000
M07 Psoriatic and enteropathic arthropathies
0.706 0.294 0.000
R06 Abnormalities of breathing
0.706 0.294 0.000
W20-W49 Exposure to inanimate mechanical forces
0.705 0.295 0.000
L10-L14 Bullous disorders
0.705 0.295 0.000
M79.5 Residual foreign body in soft tissue
0.704 0.296 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.704 0.296 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.704 0.296 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.704 0.296 0.000
J00-J06 Acute upper respiratory infections
0.703 0.296 0.000
S10-S19 Injuries to the neck
0.703 0.297 0.000
I00-I02 Acute rheumatic fever
0.703 0.297 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.702 0.298 0.000
O63.9 Long labour, unspecified
0.702 0.298 0.000
I45.9 Conduction disorder, unspecified
0.702 0.298 0.000
M79.69 Pain in limb (Site unspecified)
0.701 0.298 0.000
G50 Disorders of trigeminal nerve
0.701 0.299 0.000
R44.3 Hallucinations, unspecified
0.701 0.299 0.000
M46.96 Inflammatory spondylopathy, unspecified (Lumbar region)
0.700 0.300 0.000
H02.3 Blepharochalasis
0.699 0.301 0.000
F99-F99 Unspecified mental disorder
0.699 0.301 0.000
T66-T78 Other and unspecified effects of external causes
0.698 0.302 0.000
G58 Other mononeuropathies
0.698 0.302 0.000
M47.97 Spondylosis, unspecified (Lumbosacral region)
0.698 0.302 0.000
R46 Symptoms and signs involving appearance and behaviour
0.698 0.302 0.000
R43 Disturbances of smell and taste
0.698 0.302 0.000
L29 Pruritus
0.697 0.303 0.000
L57.0 Actinic keratosis
0.696 0.304 0.000
M20 Acquired deformities of fingers and toes
0.695 0.305 0.000
R01.0 Benign and innocent cardiac murmurs
0.694 0.306 0.000
M13 Other arthritis
0.693 0.307 0.000
I34 Nonrheumatic mitral valve disorders
0.692 0.308 0.000
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk
0.692 0.308 0.000
I67.9 Cerebrovascular disease, unspecified
0.691 0.309 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.690 0.310 0.000
F70-F79 Mental retardation
0.690 0.310 0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.690 0.310 0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.690 0.310 0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.690 0.310 0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.690 0.310 0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.690 0.310 0.000
T33-T35 Frostbite
0.689 0.311 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.689 0.311 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.689 0.311 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.689 0.311 0.000
T00-T07 Injuries involving multiple body regions
0.689 0.311 0.000
W50-W64 Exposure to animate mechanical forces
0.689 0.311 0.000
L50-L54 Urticaria and erythema
0.688 0.312 0.000
J43.8 Other emphysema
0.687 0.313 0.000
J43.2 Centrilobular emphysema
0.687 0.313 0.000
J43.1 Panlobular emphysema
0.687 0.313 0.000
J43.0 MacLeod's syndrome
0.687 0.313 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.687 0.313 0.000
H02.2 Lagophthalmos
0.686 0.314 0.000
B25-B34 Other viral diseases
0.686 0.314 0.000
M79.9 Soft tissue disorder, unspecified
0.685 0.315 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.685 0.315 0.000
M79.3 Panniculitis, unspecified
0.685 0.315 0.000
M79.2 Neuralgia and neuritis, unspecified
0.685 0.315 0.000
I50.0 Congestive heart failure
0.684 0.316 0.000
F41.0 Panic disorder [episodic paroxysmal anxiety]
0.684 0.316 0.000
H10-H13 Disorders of conjunctiva
0.684 0.316 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.684 0.316 0.000
J40 Bronchitis, not specified as acute or chronic
0.683 0.317 0.000
Z12 Special screening examination for neoplasms
0.683 0.317 0.000
F48 Other neurotic disorders
0.682 0.317 0.000
F44 Dissociative [conversion] disorders
0.682 0.317 0.000
H02.9 Disorder of eyelid, unspecified
0.683 0.317 0.000
O75.2 Pyrexia during labour, not elsewhere classified
0.682 0.318 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.682 0.318 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.682 0.318 0.000
H04.2 Epiphora
0.682 0.318 0.000
G70-G73 Diseases of myoneural junction and muscle
0.681 0.318 0.000
Z08.0 Follow-up examination after surgery for malignant neoplasm
0.681 0.319 0.000
J82 Pulmonary eosinophilia, not elsewhere classified
0.681 0.319 0.000
M46.97 Inflammatory spondylopathy, unspecified (Lumbosacral region)
0.680 0.320 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.679 0.321 0.000
I33 Acute and subacute endocarditis
0.679 0.321 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.679 0.321 0.000
Z13.8 Special screening examination for other specified diseases and disorders
0.677 0.323 0.000
Z13.7 Special screening examination for congenital malformations, deformations and chromosomal abnormalities
0.677 0.323 0.000
Z13.5 Special screening examination for eye and ear disorders
0.677 0.323 0.000
Z13.4 Special screening examination for certain developmental disorders in childhood
0.677 0.323 0.000
Z13.3 Special screening examination for mental and behavioural disorders
0.677 0.323 0.000
Z13.2 Special screening examination for nutritional disorders
0.677 0.323 0.000
I07 Rheumatic tricuspid valve diseases
0.676 0.324 0.000
J61 Pneumoconiosis due to asbestos and other mineral fibres
0.675 0.324 0.000
M92 Other juvenile osteochondrosis
0.674 0.325 0.000
M75.3 Calcific tendinitis of shoulder
0.674 0.326 0.000
F42 Obsessive-compulsive disorder
0.674 0.326 0.000
L40-L45 Papulosquamous disorders
0.674 0.326 0.000
G20-G26 Extrapyramidal and movement disorders
0.674 0.326 0.000
M75.8 Other shoulder lesions
0.673 0.327 0.000
H02.6 Xanthelasma of eyelid
0.671 0.329 0.000
R09.3 Abnormal sputum
0.671 0.329 0.000
R09.2 Respiratory arrest
0.671 0.329 0.000
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)
0.671 0.329 0.000
Y35-Y36 Legal intervention and operations of war
0.671 0.329 0.000
Y10-Y34 Event of undetermined intent
0.671 0.329 0.000
Y00-Y09 Assault
0.671 0.329 0.000
X85-X99 Assault
0.671 0.329 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.671 0.329 0.000
X50-X57 Overexertion, travel and privation
0.671 0.329 0.000
X30-X39 Exposure to forces of nature
0.671 0.329 0.000
X10-X19 Contact with heat and hot substances
0.671 0.329 0.000
X00-X09 Exposure to smoke, fire and flames
0.671 0.329 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.671 0.329 0.000
W75-W84 Other accidental threats to breathing
0.671 0.329 0.000
W65-W74 Accidental drowning and submersion
0.671 0.329 0.000
V98-V99 Other and unspecified transport accidents
0.671 0.329 0.000
V95-V97 Air and space transport accidents
0.671 0.329 0.000
V90-V94 Water transport accidents
0.671 0.329 0.000
V70-V79 Bus occupant injured in transport accident
0.671 0.329 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.671 0.329 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.671 0.329 0.000
V40-V49 Car occupant injured in transport accident
0.671 0.329 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.671 0.329 0.000
V01-V09 Pedestrian injured in transport accident
0.671 0.329 0.000
F41.8 Other specified anxiety disorders
0.670 0.330 0.000
F41.3 Other mixed anxiety disorders
0.670 0.330 0.000
G51.9 Disorder of facial nerve, unspecified
0.670 0.330 0.000
W19 Unspecified fall
0.669 0.331 0.000
M79.10 Myalgia (Multiple sites)
0.667 0.333 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.667 0.333 0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.666 0.334 0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.666 0.334 0.000
I69.1 Sequelae of intracerebral haemorrhage
0.666 0.334 0.000
V20-V29 Motorcycle rider injured in transport accident
0.666 0.334 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.665 0.334 0.000
L28 Lichen simplex chronicus and prurigo
0.664 0.336 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.664 0.336 0.000
O36.5 Maternal care for poor foetal growth
0.664 0.336 0.000
L85 Other epidermal thickening
0.663 0.337 0.000
T92.8 Sequelae of other specified injuries of upper limb
0.663 0.337 0.000
O46.9 Antepartum haemorrhage, unspecified
0.662 0.338 0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.662 0.338 0.000
L89 Decubitus ulcer
0.662 0.338 0.000
R41.3 Other amnesia
0.661 0.339 0.000
I61 Intracerebral haemorrhage
0.661 0.339 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.661 0.339 0.000
M48.06 Spinal stenosis (Lumbar region)
0.661 0.339 0.000
O69.9 Labour and delivery complicated by cord complication, unspecified
0.660 0.340 0.000
O69.8 Labour and delivery complicated by other cord complications
0.660 0.340 0.000
O69.5 Labour and delivery complicated by vascular lesion of cord
0.660 0.340 0.000
O69.4 Labour and delivery complicated by vasa praevia
0.660 0.340 0.000
O69.3 Labour and delivery complicated by short cord
0.660 0.340 0.000
O69.0 Labour and delivery complicated by prolapse of cord
0.660 0.340 0.000
F80-F89 Disorders of psychological development
0.660 0.340 0.000
M67 Other disorders of synovium and tendon
0.660 0.340 0.000
F60-F69 Disorders of adult personality and behaviour
0.658 0.342 0.000
R26 Abnormalities of gait and mobility
0.658 0.342 0.000
R94.5 Abnormal results of liver function studies
0.658 0.342 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.657 0.343 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.657 0.343 0.000
M65 Synovitis and tenosynovitis
0.657 0.343 0.000
G54 Nerve root and plexus disorders
0.657 0.343 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.657 0.343 0.000
G52 Disorders of other cranial nerves
0.657 0.343 0.000
I63.8 Other cerebral infarction
0.657 0.343 0.000
M46.8 Other specified inflammatory spondylopathies
0.656 0.344 0.000
M46.5 Other infective spondylopathies
0.656 0.344 0.000
M46.4 Discitis, unspecified
0.656 0.344 0.000
M46.3 Infection of intervertebral disk (pyogenic)
0.656 0.344 0.000
M46.2 Osteomyelitis of vertebra
0.656 0.344 0.000
M46.1 Sacro-iliitis, not elsewhere classified
0.656 0.344 0.000
M46.0 Spinal enthesopathy
0.656 0.344 0.000
M79.7 Fibromyalgia
0.656 0.344 0.000
I45.5 Other specified heart block
0.656 0.344 0.000
Q60-Q64 Congenital malformations of the urinary system
0.655 0.344 0.000
G55.2 Nerve root and plexus compressions in spondylosis
0.655 0.345 0.000
M48.5 Collapsed vertebra, not elsewhere classified
0.655 0.345 0.000
S01.2 Open wound of nose
0.654 0.346 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.654 0.346 0.000
L73 Other follicular disorders
0.654 0.346 0.000
J70 Respiratory conditions due to other external agents
0.654 0.346 0.000
J68 Respiratory conditions due to inhalation of chemicals, gases, fumes and vapours
0.654 0.346 0.000
J67 Hypersensitivity pneumonitis due to organic dust
0.654 0.346 0.000
J66 Airway disease due to specific organic dust
0.654 0.346 0.000
J63 Pneumoconiosis due to other inorganic dusts
0.654 0.346 0.000
J62 Pneumoconiosis due to dust containing silica
0.654 0.346 0.000
J65 Pneumoconiosis associated with tuberculosis
0.654 0.346 0.000
J64 Unspecified pneumoconiosis
0.654 0.346 0.000
J60 Coalworker's pneumoconiosis
0.654 0.346 0.000
O75.9 Complication of labour and delivery, unspecified
0.653 0.347 0.000
O75.5 Delayed delivery after artificial rupture of membranes
0.653 0.347 0.000
O75.4 Other complications of obstetric surgery and procedures
0.653 0.347 0.000
O75.3 Other infection during labour
0.653 0.347 0.000
O75.1 Shock during or following labour and delivery
0.653 0.347 0.000
O75.0 Maternal distress during labour and delivery
0.653 0.347 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.653 0.347 0.000
W18 Other fall on same level
0.653 0.347 0.000
Q80-Q89 Other congenital malformations
0.652 0.348 0.000
M24 Other specific joint derangements
0.652 0.348 0.000
M47.90 Spondylosis, unspecified (Multiple sites in spine)
0.651 0.349 0.000
A00-A09 Intestinal infectious diseases
0.651 0.349 0.000
M79.61 Pain in limb (Shoulder region)
0.650 0.350 0.000
T92.9 Sequelae of unspecified injury of upper limb
0.650 0.350 0.000
M79.18 Myalgia (Other)
0.649 0.351 0.000
S51 Open wound of forearm
0.649 0.351 0.000
H55 Nystagmus and other irregular eye movements
0.648 0.351 0.000
R41.2 Retrograde amnesia
0.648 0.352 0.000
R41.1 Anterograde amnesia
0.648 0.352 0.000
Z74 Problems related to care-provider dependency
0.647 0.353 0.000
O82 Single delivery by Caesarean section
0.644 0.356 0.000
L20 Atopic dermatitis
0.644 0.356 0.000
O36.0 Maternal care for rhesus isoimmunisation
0.643 0.356 0.000
O63.2 Delayed delivery of second twin, triplet, etc.
0.643 0.357 0.000
T59 Toxic effect of other gases, fumes and vapours
0.643 0.357 0.000
T90 Sequelae of injuries of head
0.641 0.358 0.000
T51 Toxic effect of alcohol
0.641 0.359 0.000
T98 Sequelae of other and unspecified effects of external causes
0.641 0.359 0.000
T95 Sequelae of burns, corrosions and frostbite
0.641 0.359 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.641 0.359 0.000
T91 Sequelae of injuries of neck and trunk
0.641 0.359 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.641 0.359 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.641 0.359 0.000
G30-G32 Other degenerative diseases of the nervous system
0.641 0.359 0.000
L02.9 Cutaneous abscess, furuncle and carbuncle, unspecified
0.641 0.359 0.000
M45 Ankylosing spondylitis
0.641 0.359 0.000
M75.0 Adhesive capsulitis of shoulder
0.640 0.360 0.000
H05 Disorders of orbit
0.640 0.360 0.000
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified
0.640 0.360 0.000
G95 Other diseases of spinal cord
0.640 0.360 0.000
R47 Speech disturbances, not elsewhere classified
0.640 0.360 0.000
J90-J94 Other diseases of pleura
0.640 0.360 0.000
Y85 Sequelae of transport accidents
0.639 0.360 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.639 0.361 0.000
M25 Other joint disorders, not elsewhere classified
0.639 0.361 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.637 0.363 0.000
I35 Nonrheumatic aortic valve disorders
0.637 0.363 0.000
S90 Superficial injury of ankle and foot
0.636 0.364 0.000
S52 Fracture of forearm
0.636 0.364 0.000
L59 Other disorders of skin and subcutaneous tissue related to radiation
0.636 0.364 0.000
L58 Radiodermatitis
0.636 0.364 0.000
L56 Other acute skin changes due to ultraviolet radiation
0.636 0.364 0.000
L55 Sunburn
0.636 0.364 0.000
S99 Other and unspecified injuries of ankle and foot
0.635 0.365 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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