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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs116350627
log Bayes Factor = 18.5363
Chromosome 3   position 1,467,635  (GRCh37) Explore rs116350627 on Ensembl!
Variant rs116350627 is part of Cluster X0229

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
Chapter XI Diseases of the digestive system
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.999 0.001 0.000
Z87 Personal history of other diseases and conditions
0.998 0.002 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.998 0.002 0.000
Z87.1 Personal history of diseases of the digestive system
0.994 0.006 0.000
Z85 Personal history of malignant neoplasm
0.993 0.007 0.000
Z85.4 Personal history of malignant neoplasm of genital organs
0.992 0.008 0.000
K65-K67 Diseases of peritoneum
0.991 0.009 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.987 0.013 0.000
I10-I15 Hypertensive diseases
0.987 0.013 0.000
S60-S69 Injuries to the wrist and hand
0.985 0.015 0.000
Chapter V Mental and behavioural disorders
0.984 0.016 0.000
K66 Other disorders of peritoneum
0.979 0.021 0.000
C15-C26 Malignant neoplasms of digestive organs
0.978 0.022 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.977 0.023 0.000
I30-I52 Other forms of heart disease
0.975 0.025 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.974 0.026 0.000
Z93 Artificial opening status
0.973 0.027 0.000
I10 Essential (primary) hypertension
0.972 0.028 0.000
S61 Open wound of wrist and hand
0.972 0.028 0.000
K66.0 Peritoneal adhesions
0.971 0.029 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.966 0.034 0.000
S61.0 Open wound of finger(s) without damage to nail
0.961 0.039 0.000
I95 Hypotension
0.956 0.044 0.000
F30-F39 Mood [affective] disorders
0.955 0.045 0.000
D10-D36 Benign neoplasms
0.954 0.046 0.000
I45 Other conduction disorders
0.952 0.048 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.950 0.050 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.948 0.052 0.000
C79 Secondary malignant neoplasm of other sites
0.944 0.056 0.000
K70-K77 Diseases of liver
0.938 0.062 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.935 0.065 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.935 0.065 0.000
K90-K93 Other diseases of the digestive system
0.932 0.068 0.000
E70-E90 Metabolic disorders
0.931 0.069 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.930 0.070 0.000
C18 Malignant neoplasm of colon
0.927 0.073 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.927 0.073 0.000
I45.1 Other and unspecified right bundle-branch block
0.926 0.074 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.922 0.078 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.920 0.080 0.000
I95.9 Hypotension, unspecified
0.920 0.080 0.000
Z90.4 Acquired absence of other parts of digestive tract
0.916 0.084 0.000
Z93.3 Colostomy status
0.912 0.088 0.000
C78.7 Secondary malignant neoplasm of liver
0.912 0.088 0.000
R10 Abdominal and pelvic pain
0.908 0.092 0.000
Z98 Other postsurgical states
0.905 0.095 0.000
C78.0 Secondary malignant neoplasm of lung
0.904 0.096 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.904 0.096 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.903 0.097 0.000
C51-C58 Malignant neoplasms of female genital organs
0.898 0.102 0.000
R13 Dysphagia
0.894 0.106 0.000
Chapter XX External causes of morbidity and mortality
0.892 0.108 0.000
E86 Volume depletion
0.891 0.109 0.000
F32 Depressive episode
0.890 0.110 0.000
Z08.0 Follow-up examination after surgery for malignant neoplasm
0.888 0.112 0.000
R21 Rash and other nonspecific skin eruption
0.884 0.116 0.000
O00-O08 Pregnancy with abortive outcome
0.883 0.117 0.000
K04 Diseases of pulp and periapical tissues
0.878 0.122 0.000
S61.8 Open wound of other parts of wrist and hand
0.874 0.126 0.000
Z87.8 Personal history of other specified conditions
0.872 0.128 0.000
Z87.7 Personal history of congenital malformations, deformations and chromosomal abnormalities
0.866 0.134 0.000
K92 Other diseases of digestive system
0.860 0.140 0.000
K35-K38 Diseases of appendix
0.857 0.143 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.857 0.143 0.000
K50-K52 Noninfective enteritis and colitis
0.856 0.144 0.000
K65 Peritonitis
0.852 0.148 0.000
C80 Malignant neoplasm without specification of site
0.850 0.150 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.847 0.153 0.000
F32.9 Depressive episode, unspecified
0.845 0.155 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.842 0.158 0.000
R10.2 Pelvic and perineal pain
0.841 0.159 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.840 0.160 0.000
Chapter VI Diseases of the nervous system
0.839 0.161 0.000
O60-O75 Complications of labour and delivery
0.838 0.162 0.000
Z02 Examination and encounter for administrative purposes
0.837 0.163 0.000
C18.7 Sigmoid colon
0.836 0.164 0.000
Z85.2 Personal history of malignant neoplasm of other respiratory and intrathoracic organs
0.834 0.166 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.832 0.168 0.000
I51 Complications and ill-defined descriptions of heart disease
0.832 0.168 0.000
I95.1 Orthostatic hypotension
0.831 0.169 0.000
K75 Other inflammatory liver diseases
0.831 0.169 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.831 0.169 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.829 0.171 0.000
K04.7 Periapical abscess without sinus
0.825 0.175 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.824 0.176 0.000
D18 Haemangioma and lymphangioma, any site
0.822 0.178 0.000
D27 Benign neoplasm of ovary
0.821 0.178 0.000
C20 Malignant neoplasm of rectum
0.820 0.180 0.000
F33 Recurrent depressive disorder
0.817 0.183 0.000
Z37 Outcome of delivery
0.814 0.186 0.000
Z93.0 Tracheostomy status
0.814 0.186 0.000
E88 Other metabolic disorders
0.812 0.188 0.000
R10.1 Pain localised to upper abdomen
0.808 0.192 0.000
Z04 Examination and observation for other reasons
0.808 0.192 0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.800 0.200 0.000
Z98.0 Intestinal bypass and anastomosis status
0.798 0.202 0.000
I11 Hypertensive heart disease
0.798 0.202 0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal
0.797 0.203 0.000
D22 Melanocytic naevi
0.796 0.204 0.000
K02 Dental caries
0.796 0.204 0.000
Z97 Presence of other devices
0.792 0.208 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.792 0.208 0.000
F31 Bipolar affective disorder
0.792 0.208 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.790 0.210 0.000
O03 Spontaneous abortion
0.790 0.210 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.790 0.210 0.000
Z13 Special screening examination for other diseases and disorders
0.788 0.212 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.785 0.215 0.000
Z93.2 Ileostomy status
0.784 0.216 0.000
K51 Ulcerative colitis
0.783 0.217 0.000
Z90.3 Acquired absence of part of stomach
0.782 0.218 0.000
S00-S09 Injuries to the head
0.782 0.218 0.000
I45.2 Bifascicular block
0.780 0.220 0.000
I71 Aortic aneurysm and dissection
0.779 0.220 0.000
S90-S99 Injuries to the ankle and foot
0.778 0.222 0.000
C55 Malignant neoplasm of uterus, part unspecified
0.775 0.225 0.000
W00-W19 Falls
0.771 0.229 0.000
R17 Unspecified jaundice
0.771 0.229 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.771 0.229 0.000
K92.0 Haematemesis
0.770 0.230 0.000
I78 Diseases of capillaries
0.770 0.230 0.000
O80-O84 Delivery
0.770 0.230 0.000
E78.5 Hyperlipidaemia, unspecified
0.770 0.230 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.769 0.231 0.000
K92.1 Melaena
0.768 0.232 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.768 0.232 0.000
Z34 Supervision of normal pregnancy
0.767 0.233 0.000
Z08.9 Follow-up examination after unspecified treatment for malignant neoplasm
0.764 0.235 0.000
D10 Benign neoplasm of mouth and pharynx
0.763 0.237 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.763 0.237 0.000
E40-E46 Malnutrition
0.763 0.237 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.763 0.237 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.762 0.238 0.000
S40-S49 Injuries to the shoulder and upper arm
0.762 0.238 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.761 0.239 0.000
S67 Crushing injury of wrist and hand
0.761 0.239 0.000
I77 Other disorders of arteries and arterioles
0.760 0.240 0.000
D32 Benign neoplasm of meninges
0.759 0.241 0.000
I30 Acute pericarditis
0.759 0.241 0.000
K14 Diseases of tongue
0.759 0.241 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.758 0.242 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.757 0.242 0.000
I42 Cardiomyopathy
0.757 0.243 0.000
I74 Arterial embolism and thrombosis
0.757 0.243 0.000
M45-M49 Spondylopathies
0.755 0.245 0.000
I51.8 Other ill-defined heart diseases
0.755 0.245 0.000
Z90.6 Acquired absence of other parts of urinary tract
0.755 0.245 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.753 0.246 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.753 0.247 0.000
Z03 Medical observation and evaluation for suspected diseases and conditions
0.753 0.247 0.000
K65.0 Acute peritonitis
0.753 0.247 0.000
W20-W49 Exposure to inanimate mechanical forces
0.752 0.248 0.000
Z90.1 Acquired absence of breast(s)
0.752 0.248 0.000
C18.0 Caecum
0.751 0.249 0.000
Z37.0 Single live birth
0.750 0.250 0.000
K72 Hepatic failure, not elsewhere classified
0.747 0.252 0.000
C78.2 Secondary malignant neoplasm of pleura
0.747 0.253 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.747 0.253 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.746 0.254 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.746 0.254 0.000
Chapter XXII Codes for special purposes
0.745 0.254 0.000
D12.0 Caecum
0.745 0.255 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.745 0.255 0.000
E20-E35 Disorders of other endocrine glands
0.745 0.255 0.000
R10.0 Acute abdomen
0.744 0.256 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.743 0.257 0.000
T66-T78 Other and unspecified effects of external causes
0.742 0.258 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.742 0.258 0.000
K76 Other diseases of liver
0.742 0.258 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.742 0.258 0.000
Z02.8 Other examinations for administrative purposes
0.740 0.260 0.000
O04 Medical abortion
0.738 0.262 0.000
Z93.5 Cystostomy status
0.738 0.262 0.000
T79-T79 Certain early complications of trauma
0.736 0.263 0.000
R10.4 Other and unspecified abdominal pain
0.736 0.264 0.000
Z90.7 Acquired absence of genital organ(s)
0.736 0.264 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.735 0.265 0.000
Z85.3 Personal history of malignant neoplasm of breast
0.735 0.265 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.734 0.266 0.000
Z98.8 Other specified postsurgical states
0.733 0.267 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.732 0.268 0.000
K00 Disorders of tooth development and eruption
0.731 0.269 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.729 0.271 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.728 0.272 0.000
S20-S29 Injuries to the thorax
0.728 0.272 0.000
D18.0 Haemangioma, any site
0.728 0.272 0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.727 0.273 0.000
I44 Atrioventricular and left bundle-branch block
0.727 0.273 0.000
F41 Other anxiety disorders
0.726 0.274 0.000
Z87.4 Personal history of diseases of the genito-urinary system
0.726 0.274 0.000
Chapter XIV Diseases of the genitourinary system
0.725 0.275 0.000
G90-G99 Other disorders of the nervous system
0.723 0.277 0.000
S64 Injury of nerves at wrist and hand level
0.721 0.279 0.000
I12 Hypertensive renal disease
0.721 0.279 0.000
K35 Acute appendicitis
0.721 0.279 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.720 0.280 0.000
I47 Paroxysmal tachycardia
0.719 0.281 0.000
Z87.3 Personal history of diseases of the musculoskeletal system and connective tissue
0.718 0.281 0.000
X60-X84 Intentional self-harm
0.718 0.282 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.717 0.283 0.000
Z89 Acquired absence of limb
0.717 0.283 0.000
Z84 Family history of other conditions
0.717 0.283 0.000
Z81 Family history of mental and behavioural disorders
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Z32 Pregnancy examination and test
0.717 0.283 0.000
C54 Malignant neoplasm of corpus uteri
0.717 0.283 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.716 0.283 0.000
T33-T35 Frostbite
0.716 0.284 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.716 0.284 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.716 0.284 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.716 0.284 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.716 0.284 0.000
T00-T07 Injuries involving multiple body regions
0.716 0.284 0.000
S10-S19 Injuries to the neck
0.716 0.284 0.000
Z87.6 Personal history of certain conditions arising in the perinatal period
0.716 0.284 0.000
Z87.5 Personal history of complications of pregnancy, childbirth and the puerperium
0.716 0.284 0.000
Z35 Supervision of high-risk pregnancy
0.716 0.284 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.715 0.285 0.000
K70 Alcoholic liver disease
0.715 0.285 0.000
Z93.6 Other artificial openings of urinary tract status
0.715 0.285 0.000
C25 Malignant neoplasm of pancreas
0.715 0.285 0.000
I46 Cardiac arrest
0.715 0.285 0.000
Z90.0 Acquired absence of part of head and neck
0.713 0.287 0.000
Z85.0 Personal history of malignant neoplasm of digestive organs
0.712 0.288 0.000
Z85.9 Personal history of malignant neoplasm, unspecified
0.712 0.288 0.000
K51.9 Ulcerative colitis, unspecified
0.711 0.289 0.000
M15-M19 Arthrosis
0.711 0.289 0.000
K67 Disorders of peritoneum in infectious diseases classified elsewhere
0.711 0.289 0.000
C18.4 Transverse colon
0.708 0.292 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.708 0.292 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.707 0.292 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.707 0.292 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.707 0.292 0.000
I15 Secondary hypertension
0.707 0.293 0.000
I13 Hypertensive heart and renal disease
0.707 0.293 0.000
I33 Acute and subacute endocarditis
0.707 0.293 0.000
S69 Other and unspecified injuries of wrist and hand
0.706 0.294 0.000
S65 Injury of blood vessels at wrist and hand level
0.706 0.294 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.706 0.294 0.000
S60 Superficial injury of wrist and hand
0.706 0.294 0.000
I95.2 Hypotension due to drugs
0.706 0.294 0.000
F99-F99 Unspecified mental disorder
0.705 0.295 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.705 0.295 0.000
F80-F89 Disorders of psychological development
0.705 0.295 0.000
F70-F79 Mental retardation
0.705 0.295 0.000
F60-F69 Disorders of adult personality and behaviour
0.705 0.295 0.000
E50-E64 Other nutritional deficiencies
0.705 0.295 0.000
Z85.6 Personal history of leukaemia
0.705 0.295 0.000
I49 Other cardiac arrhythmias
0.704 0.296 0.000
M47 Spondylosis
0.704 0.296 0.000
O03.4 Incomplete, without complication
0.703 0.297 0.000
Z91.5 Personal history of self-harm
0.703 0.297 0.000
C80.0 Malignant neoplasm, primary site unknown, so stated
0.703 0.297 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.703 0.297 0.000
K66.9 Disorder of peritoneum, unspecified
0.702 0.298 0.000
K66.8 Other specified disorders of peritoneum
0.702 0.298 0.000
K66.1 Haemoperitoneum
0.702 0.298 0.000
D36 Benign neoplasm of other and unspecified sites
0.702 0.298 0.000
K12 Stomatitis and related lesions
0.701 0.298 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.701 0.299 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.701 0.299 0.000
C21 Malignant neoplasm of anus and anal canal
0.701 0.299 0.000
C17 Malignant neoplasm of small intestine
0.701 0.299 0.000
C16 Malignant neoplasm of stomach
0.701 0.299 0.000
C23 Malignant neoplasm of gallbladder
0.701 0.299 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.701 0.299 0.000
I99 Other and unspecified disorders of circulatory system
0.701 0.299 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.700 0.300 0.000
I05-I09 Chronic rheumatic heart diseases
0.700 0.300 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.699 0.301 0.000
I52 Other heart disorders in diseases classified elsewhere
0.699 0.301 0.000
I48 Atrial fibrillation and flutter
0.699 0.301 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.699 0.301 0.000
I41 Myocarditis in diseases classified elsewhere
0.699 0.301 0.000
I40 Acute myocarditis
0.699 0.301 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.699 0.301 0.000
I37 Pulmonary valve disorders
0.699 0.301 0.000
I36 Nonrheumatic tricuspid valve disorders
0.699 0.301 0.000
I32 Pericarditis in diseases classified elsewhere
0.699 0.301 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.699 0.301 0.000
D13 Benign neoplasm of other and ill-defined parts of digestive system
0.698 0.302 0.000
Z10 Routine general health check-up of defined subpopulation
0.698 0.302 0.000
Z93.9 Artificial opening status, unspecified
0.698 0.302 0.000
Z93.8 Other artificial opening status
0.698 0.302 0.000
Z93.4 Other artificial openings of gastro-intestinal tract status
0.698 0.302 0.000
Z93.1 Gastrostomy status
0.698 0.302 0.000
Z83 Family history of other specific disorders
0.697 0.302 0.000
K75.4 Autoimmune hepatitis
0.697 0.303 0.000
S61.7 Multiple open wounds of wrist and hand
0.697 0.303 0.000
S68 Traumatic amputation of wrist and hand
0.696 0.304 0.000
K74 Fibrosis and cirrhosis of liver
0.696 0.304 0.000
K02.9 Dental caries, unspecified
0.696 0.304 0.000
R18 Ascites
0.695 0.305 0.000
C18.9 Colon, unspecified
0.695 0.305 0.000
C18.2 Ascending colon
0.694 0.306 0.000
Z85.7 Personal history of other malignant neoplasms of lymphoid, haematopoietic and related tissues
0.693 0.307 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.692 0.308 0.000
Z87.0 Personal history of diseases of the respiratory system
0.692 0.308 0.000
C18.6 Descending colon
0.692 0.308 0.000
K04.6 Periapical abscess with sinus
0.692 0.308 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.692 0.308 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.690 0.309 0.000
S50-S59 Injuries to the elbow and forearm
0.690 0.310 0.000
Z94 Transplanted organ and tissue status
0.690 0.310 0.000
V10-V19 Pedal cyclist injured in transport accident
0.688 0.312 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.688 0.312 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.688 0.312 0.000
Z13.6 Special screening examination for cardiovascular disorders
0.687 0.313 0.000
K04.5 Chronic apical periodontitis
0.686 0.314 0.000
C56 Malignant neoplasm of ovary
0.685 0.314 0.000
I95.8 Other hypotension
0.685 0.315 0.000
I95.0 Idiopathic hypotension
0.685 0.315 0.000
F38 Other mood [affective] disorders
0.685 0.315 0.000
F34 Persistent mood [affective] disorders
0.685 0.315 0.000
F30 Manic episode
0.685 0.315 0.000
F39 Unspecified mood [affective] disorder
0.685 0.315 0.000
Z87.2 Personal history of diseases of the skin and subcutaneous tissue
0.685 0.315 0.000
W19 Unspecified fall
0.685 0.315 0.000
D33 Benign neoplasm of brain and other parts of central nervous system
0.684 0.316 0.000
D31 Benign neoplasm of eye and adnexa
0.684 0.316 0.000
D30 Benign neoplasm of urinary organs
0.684 0.316 0.000
D29 Benign neoplasm of male genital organs
0.684 0.316 0.000
D28 Benign neoplasm of other and unspecified female genital organs
0.684 0.316 0.000
D26 Other benign neoplasms of uterus
0.684 0.316 0.000
D21 Other benign neoplasms of connective and other soft tissue
0.684 0.316 0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum
0.684 0.316 0.000
D19 Benign neoplasm of mesothelial tissue
0.684 0.316 0.000
D16 Benign neoplasm of bone and articular cartilage
0.684 0.316 0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs
0.684 0.316 0.000
D14 Benign neoplasm of middle ear and respiratory system
0.684 0.316 0.000
D34 Benign neoplasm of thyroid gland
0.684 0.316 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.684 0.316 0.000
I35 Nonrheumatic aortic valve disorders
0.684 0.316 0.000
Z08.7 Follow-up examination after combined treatment for malignant neoplasm
0.682 0.317 0.000
I45.9 Conduction disorder, unspecified
0.682 0.318 0.000
I45.8 Other specified conduction disorders
0.682 0.318 0.000
I45.6 Preexcitation syndrome
0.682 0.318 0.000
I45.5 Other specified heart block
0.682 0.318 0.000
I45.4 Nonspecific intraventricular block
0.682 0.318 0.000
I45.3 Trifascicular block
0.682 0.318 0.000
I45.0 Right fascicular block
0.682 0.318 0.000
K83 Other diseases of biliary tract
0.682 0.318 0.000
O00 Ectopic pregnancy
0.681 0.319 0.000
O85-O92 Complications predominantly related to the puerperium
0.680 0.320 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.680 0.320 0.000
S80-S89 Injuries to the knee and lower leg
0.680 0.320 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.679 0.321 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.679 0.321 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.678 0.322 0.000
C79.6 Secondary malignant neoplasm of ovary
0.676 0.323 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.676 0.323 0.000
C79.2 Secondary malignant neoplasm of skin
0.676 0.323 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.676 0.323 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.676 0.323 0.000
N17-N19 Renal failure
0.676 0.324 0.000
Z03.5 Observation for other suspected cardiovascular diseases
0.676 0.324 0.000
C80.9 Malignant neoplasm, unspecified
0.675 0.324 0.000
Z90.8 Acquired absence of other organs
0.674 0.326 0.000
F31.9 Bipolar affective disorder, unspecified
0.674 0.326 0.000
K38 Other diseases of appendix
0.674 0.326 0.000
Chapter VIII Diseases of the ear and mastoid process
0.673 0.327 0.000
K77 Liver disorders in diseases classified elsewhere
0.673 0.327 0.000
K73 Chronic hepatitis, not elsewhere classified
0.673 0.327 0.000
K71 Toxic liver disease
0.673 0.327 0.000
O70 Perineal laceration during delivery
0.673 0.327 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.672 0.328 0.000
R12 Heartburn
0.671 0.328 0.000
M47.8 Other spondylosis
0.671 0.329 0.000
K10 Other diseases of jaws
0.671 0.329 0.000
K09 Cysts of oral region, not elsewhere classified
0.671 0.329 0.000
K07 Dentofacial anomalies [including malocclusion]
0.671 0.329 0.000
K06 Other disorders of gingiva and edentulous alveolar ridge
0.671 0.329 0.000
K03 Other diseases of hard tissues of teeth
0.671 0.329 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.671 0.329 0.000
S62 Fracture at wrist and hand level
0.670 0.330 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.670 0.330 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.670 0.330 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.669 0.331 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.669 0.331 0.000
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms
0.669 0.331 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.669 0.331 0.000
D23 Other benign neoplasms of skin
0.668 0.332 0.000
E85 Amyloidosis
0.668 0.332 0.000
E84 Cystic fibrosis
0.668 0.332 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.668 0.332 0.000
E79 Disorders of purine and pyrimidine metabolism
0.668 0.332 0.000
E77 Disorders of glycoprotein metabolism
0.668 0.332 0.000
E76 Disorders of glycosaminoglycan metabolism
0.668 0.332 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.668 0.332 0.000
E74 Other disorders of carbohydrate metabolism
0.668 0.332 0.000
E73 Lactose intolerance
0.668 0.332 0.000
E72 Other disorders of amino-acid metabolism
0.668 0.332 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.668 0.332 0.000
E70 Disorders of aromatic amino-acid metabolism
0.668 0.332 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.668 0.332 0.000
Z08.1 Follow-up examination after radiotherapy for malignant neoplasm
0.667 0.333 0.000
C18.8 Overlapping lesion of colon
0.665 0.335 0.000
C18.5 Splenic flexure
0.665 0.335 0.000
C18.3 Hepatic flexure
0.665 0.335 0.000
C18.1 Appendix
0.665 0.335 0.000
N40-N51 Diseases of male genital organs
0.665 0.335 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.665 0.335 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.665 0.335 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.665 0.335 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.665 0.335 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.665 0.335 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.665 0.335 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.665 0.335 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.665 0.335 0.000
T36 Poisoning by systemic antibiotics
0.665 0.335 0.000
D12.4 Descending colon
0.665 0.335 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.664 0.336 0.000
I78.1 Naevus, nonneoplastic
0.663 0.337 0.000
I11.9 Hypertensive heart disease without (congestive) heart failure
0.663 0.337 0.000
E78.0 Pure hypercholesterolaemia
0.663 0.337 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.662 0.338 0.000
Z98.1 Arthrodesis status
0.661 0.338 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.661 0.339 0.000
F33.9 Recurrent depressive disorder, unspecified
0.661 0.339 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.661 0.339 0.000
F41.9 Anxiety disorder, unspecified
0.660 0.340 0.000
D17 Benign lipomatous neoplasm
0.660 0.340 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.660 0.340 0.000
I72 Other aneurysm
0.660 0.340 0.000
I70 Atherosclerosis
0.660 0.340 0.000
Z13.9 Special screening examination, unspecified
0.659 0.341 0.000
T40.2 Other opioids
0.659 0.341 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.658 0.342 0.000
R10.3 Pain localised to other parts of lower abdomen
0.658 0.342 0.000
K75.0 Abscess of liver
0.658 0.342 0.000
K05 Gingivitis and periodontal diseases
0.657 0.342 0.000
D11 Benign neoplasm of major salivary glands
0.657 0.343 0.000
V20-V29 Motorcycle rider injured in transport accident
0.655 0.345 0.000
K91.3 Postoperative intestinal obstruction
0.655 0.345 0.000
F32.1 Moderate depressive episode
0.654 0.346 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.653 0.347 0.000
Z43 Attention to artificial openings
0.653 0.347 0.000
Z97.5 Presence of (intra-uterine) contraceptive device
0.652 0.348 0.000
K91.4 Colostomy and enterostomy malfunction
0.651 0.349 0.000
K85 Acute pancreatitis
0.651 0.349 0.000
C53 Malignant neoplasm of cervix uteri
0.649 0.351 0.000
Z98.2 Presence of cerebrospinal fluid drainage device
0.649 0.351 0.000
I50 Heart failure
0.648 0.352 0.000
R23 Other skin changes
0.648 0.352 0.000
Z38 Liveborn infants according to place of birth
0.648 0.352 0.000
Z31 Procreative management
0.648 0.352 0.000
K75.9 Inflammatory liver disease, unspecified
0.645 0.355 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.645 0.355 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.645 0.355 0.000
C57 Malignant neoplasm of other and unspecified female genital organs
0.644 0.356 0.000
C51 Malignant neoplasm of vulva
0.644 0.356 0.000
C58 Malignant neoplasm of placenta
0.644 0.356 0.000
C52 Malignant neoplasm of vagina
0.644 0.356 0.000
I44.7 Left bundle-branch block, unspecified
0.644 0.356 0.000
K76.8 Other specified diseases of liver
0.643 0.357 0.000
F32.3 Severe depressive episode with psychotic symptoms
0.643 0.357 0.000
Z39 Postpartum care and examination
0.642 0.358 0.000
E00-E07 Disorders of thyroid gland
0.642 0.358 0.000
M47.86 Other spondylosis (Lumbar region)
0.641 0.359 0.000
C64-C68 Malignant neoplasms of urinary tract
0.641 0.359 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.640 0.360 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.640 0.360 0.000
Y35-Y36 Legal intervention and operations of war
0.640 0.360 0.000
Y10-Y34 Event of undetermined intent
0.640 0.360 0.000
Y00-Y09 Assault
0.640 0.360 0.000
X85-X99 Assault
0.640 0.360 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.640 0.360 0.000
X50-X57 Overexertion, travel and privation
0.640 0.360 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.640 0.360 0.000
X30-X39 Exposure to forces of nature
0.640 0.360 0.000
X20-X29 Contact with venomous animals and plants
0.640 0.360 0.000
X10-X19 Contact with heat and hot substances
0.640 0.360 0.000
X00-X09 Exposure to smoke, fire and flames
0.640 0.360 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.640 0.360 0.000
W75-W84 Other accidental threats to breathing
0.640 0.360 0.000
W65-W74 Accidental drowning and submersion
0.640 0.360 0.000
W50-W64 Exposure to animate mechanical forces
0.640 0.360 0.000
V98-V99 Other and unspecified transport accidents
0.640 0.360 0.000
V95-V97 Air and space transport accidents
0.640 0.360 0.000
V90-V94 Water transport accidents
0.640 0.360 0.000
V80-V89 Other land transport accidents
0.640 0.360 0.000
V70-V79 Bus occupant injured in transport accident
0.640 0.360 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.640 0.360 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.640 0.360 0.000
V40-V49 Car occupant injured in transport accident
0.640 0.360 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.640 0.360 0.000
V01-V09 Pedestrian injured in transport accident
0.640 0.360 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.640 0.360 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.640 0.360 0.000
D22.3 Melanocytic naevi of other and unspecified parts of face
0.639 0.361 0.000
F32.8 Other depressive episodes
0.638 0.361 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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