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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs116419863
log Bayes Factor = 28.8746
Chromosome 2   position 79,917,975  (GRCh37) Explore rs116419863 on Ensembl!
Variant rs116419863 is part of Cluster X0067

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XI Diseases of the digestive system
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
K55-K64 Other diseases of intestines
1.000 0.000 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.999 0.001 0.000
Chapter VI Diseases of the nervous system
0.998 0.002 0.000
M20-M25 Other joint disorders
0.997 0.003 0.000
Chapter XXI Factors influencing health status and contact with health services
0.997 0.003 0.000
Chapter XIV Diseases of the genitourinary system
0.996 0.004 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.994 0.006 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.993 0.007 0.000
Z87 Personal history of other diseases and conditions
0.993 0.007 0.000
Chapter XX External causes of morbidity and mortality
0.993 0.007 0.000
Z87.1 Personal history of diseases of the digestive system
0.993 0.007 0.000
M25 Other joint disorders, not elsewhere classified
0.992 0.008 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.991 0.009 0.000
D10-D36 Benign neoplasms
0.990 0.010 0.000
E65-E68 Obesity and other hyperalimentation
0.990 0.010 0.000
K70-K77 Diseases of liver
0.990 0.010 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.987 0.013 0.000
E66 Obesity
0.987 0.013 0.000
Chapter X Diseases of the respiratory system
0.982 0.018 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.980 0.020 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.980 0.020 0.000
K61 Abscess of anal and rectal regions
0.973 0.027 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.973 0.027 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.971 0.029 0.000
T81 Complications of procedures, not elsewhere classified
0.970 0.030 0.000
K62 Other diseases of anus and rectum
0.970 0.030 0.000
D23 Other benign neoplasms of skin
0.968 0.032 0.000
J09-J18 Influenza and pneumonia
0.967 0.033 0.000
E66.9 Obesity, unspecified
0.965 0.035 0.000
K76 Other diseases of liver
0.964 0.036 0.000
D25 Leiomyoma of uterus
0.963 0.037 0.000
M25.5 Pain in joint
0.962 0.038 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.962 0.038 0.000
N25-N29 Other disorders of kidney and ureter
0.959 0.041 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.958 0.042 0.000
E66.8 Other obesity
0.958 0.042 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.957 0.043 0.000
C51-C58 Malignant neoplasms of female genital organs
0.957 0.043 0.000
K61.0 Anal abscess
0.957 0.043 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.957 0.043 0.000
N80 Endometriosis
0.957 0.043 0.000
D25.9 Leiomyoma of uterus, unspecified
0.956 0.044 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.954 0.046 0.000
M25.7 Osteophyte
0.952 0.048 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.950 0.050 0.000
T81.8 Other complications of procedures, not elsewhere classified
0.950 0.050 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.949 0.051 0.000
Chapter VII Diseases of the eye and adnexa
0.945 0.055 0.000
G40-G47 Episodic and paroxysmal disorders
0.944 0.056 0.000
D23.5 Skin of trunk
0.942 0.058 0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts
0.940 0.060 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.940 0.060 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.938 0.062 0.000
K76.8 Other specified diseases of liver
0.935 0.065 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.932 0.068 0.000
C44 Other malignant neoplasms of skin
0.930 0.070 0.000
K62.8 Other specified diseases of anus and rectum
0.930 0.070 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.929 0.071 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.928 0.072 0.000
D24 Benign neoplasm of breast
0.928 0.072 0.000
N28 Other disorders of kidney and ureter, not elsewhere classified
0.927 0.073 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.927 0.073 0.000
M70-M79 Other soft tissue disorders
0.925 0.075 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.925 0.075 0.000
J18 Pneumonia, organism unspecified
0.923 0.077 0.000
N80.1 Endometriosis of ovary
0.922 0.078 0.000
K56 Paralytic ileus and intestinal obstruction without hernia
0.922 0.078 0.000
H53-H54 Visual disturbances and blindness
0.920 0.080 0.000
Z96 Presence of other functional implants
0.920 0.080 0.000
N73 Other female pelvic inflammatory diseases
0.917 0.083 0.000
G90-G99 Other disorders of the nervous system
0.915 0.085 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.914 0.086 0.000
C44.4 Skin of scalp and neck
0.913 0.087 0.000
N20-N23 Urolithiasis
0.913 0.087 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.913 0.087 0.000
M21 Other acquired deformities of limbs
0.911 0.089 0.000
C56 Malignant neoplasm of ovary
0.909 0.091 0.000
G56 Mononeuropathies of upper limb
0.906 0.094 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.905 0.095 0.000
Chapter IX Diseases of the circulatory system
0.904 0.096 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.899 0.101 0.000
L57 Skin changes due to chronic exposure to nonionising radiation
0.899 0.101 0.000
Y86 Sequelae of other accidents
0.897 0.103 0.000
Z93 Artificial opening status
0.897 0.103 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.897 0.103 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.896 0.104 0.000
K81 Cholecystitis
0.896 0.104 0.000
K83 Other diseases of biliary tract
0.895 0.105 0.000
N73.6 Female pelvic peritoneal adhesions
0.893 0.107 0.000
M15-M19 Arthrosis
0.892 0.108 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.892 0.108 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.891 0.109 0.000
J90-J94 Other diseases of pleura
0.888 0.112 0.000
D45 Polycythaemia vera
0.886 0.113 0.000
M24 Other specific joint derangements
0.884 0.116 0.000
N28.9 Disorder of kidney and ureter, unspecified
0.884 0.116 0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified
0.880 0.120 0.000
C79 Secondary malignant neoplasm of other sites
0.879 0.121 0.000
C44.1 Skin of eyelid, including canthus
0.879 0.121 0.000
M40-M43 Deforming dorsopathies
0.879 0.121 0.000
G56.0 Carpal tunnel syndrome
0.878 0.122 0.000
R18 Ascites
0.878 0.122 0.000
M50-M54 Other dorsopathies
0.877 0.123 0.000
Z90.1 Acquired absence of breast(s)
0.876 0.124 0.000
Z87.7 Personal history of congenital malformations, deformations and chromosomal abnormalities
0.875 0.125 0.000
R15 Faecal incontinence
0.873 0.127 0.000
K62.4 Stenosis of anus and rectum
0.872 0.128 0.000
N21 Calculus of lower urinary tract
0.871 0.129 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.871 0.129 0.000
K63 Other diseases of intestine
0.869 0.131 0.000
K56.6 Other and unspecified intestinal obstruction
0.868 0.132 0.000
M86-M90 Other osteopathies
0.868 0.132 0.000
N86 Erosion and ectropion of cervix uteri
0.868 0.132 0.000
H54 Blindness and low vision
0.866 0.134 0.000
L57.0 Actinic keratosis
0.865 0.135 0.000
M25.77 Osteophyte (Ankle and foot)
0.865 0.135 0.000
N00-N08 Glomerular diseases
0.864 0.135 0.000
M25.53 Pain in joint (Forearm)
0.864 0.136 0.000
M31 Other necrotising vasculopathies
0.864 0.136 0.000
R25 Abnormal involuntary movements
0.863 0.137 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.862 0.138 0.000
K70 Alcoholic liver disease
0.862 0.138 0.000
D23.4 Skin of scalp and neck
0.861 0.139 0.000
Z74 Problems related to care-provider dependency
0.861 0.139 0.000
R16 Hepatomegaly and splenomegaly, not elsewhere classified
0.860 0.140 0.000
M25.76 Osteophyte (Lower leg)
0.860 0.140 0.000
K60 Fissure and fistula of anal and rectal regions
0.860 0.140 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.859 0.141 0.000
K65-K67 Diseases of peritoneum
0.858 0.142 0.000
D23.2 Skin of ear and external auricular canal
0.856 0.144 0.000
N80.2 Endometriosis of Fallopian tube
0.855 0.145 0.000
N85 Other noninflammatory disorders of uterus, except cervix
0.855 0.145 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.854 0.146 0.000
N84 Polyp of female genital tract
0.853 0.147 0.000
N70 Salpingitis and oophoritis
0.851 0.149 0.000
N76 Other inflammation of vagina and vulva
0.851 0.149 0.000
Chapter XXII Codes for special purposes
0.848 0.152 0.000
I30-I52 Other forms of heart disease
0.847 0.153 0.000
Z83 Family history of other specific disorders
0.846 0.154 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.844 0.156 0.000
Z87.0 Personal history of diseases of the respiratory system
0.844 0.156 0.000
T51 Toxic effect of alcohol
0.844 0.156 0.000
R93.2 Abnormal findings on diagnostic imaging of liver and biliary tract
0.843 0.157 0.000
K35-K38 Diseases of appendix
0.843 0.157 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.843 0.157 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.842 0.158 0.000
N21.0 Calculus in bladder
0.841 0.159 0.000
R45 Symptoms and signs involving emotional state
0.840 0.160 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.840 0.160 0.000
E10-E14 Diabetes mellitus
0.839 0.161 0.000
K83.0 Cholangitis
0.839 0.161 0.000
Z90.5 Acquired absence of kidney
0.838 0.162 0.000
K86 Other diseases of pancreas
0.835 0.165 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.834 0.166 0.000
H53 Visual disturbances
0.833 0.167 0.000
Z90.3 Acquired absence of part of stomach
0.832 0.168 0.000
K81.0 Acute cholecystitis
0.830 0.170 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.830 0.170 0.000
J90 Pleural effusion, not elsewhere classified
0.828 0.172 0.000
M25.51 Pain in joint (Shoulder region)
0.828 0.172 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.827 0.173 0.000
M16 Coxarthrosis [arthrosis of hip]
0.826 0.174 0.000
K90-K93 Other diseases of the digestive system
0.823 0.177 0.000
M65-M68 Disorders of synovium and tendon
0.821 0.179 0.000
K20-K31 Diseases of oesophagus, stomach and duodenum
0.821 0.179 0.000
G81 Hemiplegia
0.818 0.182 0.000
C64-C68 Malignant neoplasms of urinary tract
0.818 0.182 0.000
K62.6 Ulcer of anus and rectum
0.817 0.183 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.816 0.184 0.000
K76.0 Fatty (change of) liver, not elsewhere classified
0.814 0.186 0.000
K31 Other diseases of stomach and duodenum
0.814 0.186 0.000
Y84.8 Other medical procedures
0.814 0.186 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.813 0.187 0.000
R16.1 Splenomegaly, not elsewhere classified
0.812 0.188 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.812 0.188 0.000
J60-J70 Lung diseases due to external agents
0.809 0.191 0.000
Z73 Problems related to life-management difficulty
0.808 0.192 0.000
M21.0 Valgus deformity, not elsewhere classified
0.808 0.192 0.000
K31.7 Polyp of stomach and duodenum
0.808 0.192 0.000
N88 Other noninflammatory disorders of cervix uteri
0.807 0.193 0.000
T85.1 Mechanical complication of implanted electronic stimulator of nervous system
0.805 0.195 0.000
S50-S59 Injuries to the elbow and forearm
0.805 0.195 0.000
J18.9 Pneumonia, unspecified
0.805 0.195 0.000
R94 Abnormal results of function studies
0.804 0.196 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.804 0.196 0.000
G93 Other disorders of brain
0.803 0.197 0.000
R25.1 Tremor, unspecified
0.803 0.197 0.000
Chapter I Certain infectious and parasitic diseases
0.803 0.197 0.000
T51.0 Ethanol
0.802 0.198 0.000
G43 Migraine
0.802 0.198 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.802 0.198 0.000
N89 Other noninflammatory disorders of vagina
0.800 0.200 0.000
Z96.6 Presence of orthopaedic joint implants
0.799 0.201 0.000
K63.5 Polyp of colon
0.798 0.202 0.000
N72 Inflammatory disease of cervix uteri
0.797 0.203 0.000
M54 Dorsalgia
0.796 0.204 0.000
K62.3 Rectal prolapse
0.794 0.206 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.793 0.207 0.000
G80 Infantile cerebral palsy
0.792 0.208 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.791 0.209 0.000
N80.8 Other endometriosis
0.791 0.209 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.791 0.209 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.791 0.209 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.790 0.210 0.000
H10-H13 Disorders of conjunctiva
0.790 0.210 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.790 0.210 0.000
H54.9 Unspecified visual impairment (binocular)
0.790 0.210 0.000
M05-M14 Inflammatory polyarthropathies
0.790 0.210 0.000
M25.52 Pain in joint (Upper arm)
0.789 0.211 0.000
M79.8 Other specified soft tissue disorders
0.787 0.213 0.000
T81.4 Infection following a procedure, not elsewhere classified
0.787 0.213 0.000
I46 Cardiac arrest
0.786 0.214 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.785 0.215 0.000
Z85 Personal history of malignant neoplasm
0.784 0.216 0.000
K73 Chronic hepatitis, not elsewhere classified
0.784 0.216 0.000
I51 Complications and ill-defined descriptions of heart disease
0.783 0.217 0.000
M25.75 Osteophyte (Pelvic region and thigh)
0.782 0.218 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.782 0.218 0.000
D21 Other benign neoplasms of connective and other soft tissue
0.781 0.218 0.000
M16.9 Coxarthrosis, unspecified
0.781 0.219 0.000
K75 Other inflammatory liver diseases
0.780 0.220 0.000
D37.5 Rectum
0.778 0.222 0.000
M25.50 Pain in joint (Multiple sites)
0.777 0.223 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.776 0.224 0.000
L03 Cellulitis
0.775 0.225 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.775 0.225 0.000
N28.8 Other specified disorders of kidney and ureter
0.774 0.225 0.000
N84.0 Polyp of corpus uteri
0.774 0.226 0.000
M25.59 Pain in joint (Site unspecified)
0.774 0.226 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.773 0.227 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.773 0.227 0.000
J18.0 Bronchopneumonia, unspecified
0.773 0.227 0.000
Z91.6 Personal history of other physical trauma
0.773 0.227 0.000
Q50-Q56 Congenital malformations of genital organs
0.773 0.227 0.000
Z97 Presence of other devices
0.772 0.228 0.000
S10-S19 Injuries to the neck
0.772 0.228 0.000
I60-I69 Cerebrovascular diseases
0.772 0.228 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.772 0.228 0.000
T85.9 Unspecified complication of internal prosthetic device, implant and graft
0.772 0.228 0.000
K81.1 Chronic cholecystitis
0.771 0.229 0.000
W20-W49 Exposure to inanimate mechanical forces
0.771 0.229 0.000
Z90.6 Acquired absence of other parts of urinary tract
0.771 0.229 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.770 0.230 0.000
Z74.0 Reduced mobility
0.770 0.230 0.000
N85.8 Other specified noninflammatory disorders of uterus
0.769 0.231 0.000
Z87.3 Personal history of diseases of the musculoskeletal system and connective tissue
0.769 0.231 0.000
M31.6 Other giant cell arteritis
0.768 0.231 0.000
G70-G73 Diseases of myoneural junction and muscle
0.768 0.232 0.000
R27 Other lack of coordination
0.768 0.232 0.000
D32 Benign neoplasm of meninges
0.767 0.233 0.000
Z85.8 Personal history of malignant neoplasms of other organs and systems
0.767 0.233 0.000
T81.1 Shock during or resulting from a procedure, not elsewhere classified
0.765 0.235 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.765 0.235 0.000
E65 Localised adiposity
0.764 0.236 0.000
K36 Other appendicitis
0.764 0.236 0.000
M43 Other deforming dorsopathies
0.764 0.236 0.000
N23 Unspecified renal colic
0.763 0.237 0.000
Z93.3 Colostomy status
0.763 0.237 0.000
G45.9 Transient cerebral ischaemic attack, unspecified
0.763 0.237 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.762 0.238 0.000
D26 Other benign neoplasms of uterus
0.762 0.238 0.000
N80.5 Endometriosis of intestine
0.762 0.238 0.000
K26 Duodenal ulcer
0.762 0.238 0.000
Z83.7 Family history of diseases of the digestive system
0.762 0.238 0.000
T82.1 Mechanical complication of cardiac electronic device
0.762 0.238 0.000
H53.1 Subjective visual disturbances
0.762 0.238 0.000
D46 Myelodysplastic syndromes
0.761 0.239 0.000
K65 Peritonitis
0.761 0.239 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.761 0.239 0.000
J18.8 Other pneumonia, organism unspecified
0.761 0.239 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.760 0.240 0.000
M18 Arthrosis of first carpometacarpal joint
0.760 0.240 0.000
I45 Other conduction disorders
0.760 0.240 0.000
M60-M63 Disorders of muscles
0.759 0.241 0.000
V40-V49 Car occupant injured in transport accident
0.759 0.241 0.000
R41.2 Retrograde amnesia
0.759 0.241 0.000
S90-S99 Injuries to the ankle and foot
0.759 0.241 0.000
X60-X84 Intentional self-harm
0.758 0.242 0.000
Z96.8 Presence of other specified functional implants
0.757 0.243 0.000
E00-E07 Disorders of thyroid gland
0.757 0.243 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.755 0.244 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.755 0.245 0.000
T79-T79 Certain early complications of trauma
0.755 0.245 0.000
L57.8 Other skin changes due to chronic exposure to nonionising radiation
0.754 0.246 0.000
D34 Benign neoplasm of thyroid gland
0.753 0.247 0.000
M54.5 Low back pain
0.753 0.247 0.000
N76.0 Acute vaginitis
0.753 0.247 0.000
T85.2 Mechanical complication of intraocular lens
0.752 0.247 0.000
S70-S79 Injuries to the hip and thigh
0.752 0.248 0.000
R93.3 Abnormal findings on diagnostic imaging of other parts of digestive tract
0.751 0.249 0.000
N04 Nephrotic syndrome
0.751 0.249 0.000
D27 Benign neoplasm of ovary
0.751 0.249 0.000
C78.7 Secondary malignant neoplasm of liver
0.750 0.250 0.000
Z53 Persons encountering health services for specifie procedures, not carried out
0.750 0.250 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.749 0.251 0.000
Z96.0 Presence of urogenital implants
0.749 0.251 0.000
D37.7 Other digestive organs
0.749 0.251 0.000
K56.1 Intussusception
0.748 0.252 0.000
K86.9 Disease of pancreas, unspecified
0.748 0.252 0.000
K62.7 Radiation proctitis
0.746 0.253 0.000
C54 Malignant neoplasm of corpus uteri
0.746 0.254 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.746 0.254 0.000
G90 Disorders of autonomic nervous system
0.746 0.254 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.745 0.255 0.000
M25.3 Other instability of joint
0.744 0.256 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.743 0.257 0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts
0.743 0.257 0.000
C15-C26 Malignant neoplasms of digestive organs
0.743 0.257 0.000
R40 Somnolence, stupor and coma
0.743 0.257 0.000
M25.8 Other specified joint disorders
0.741 0.259 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.741 0.259 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.741 0.259 0.000
R17 Unspecified jaundice
0.739 0.261 0.000
N26 Unspecified contracted kidney
0.739 0.261 0.000
S40-S49 Injuries to the shoulder and upper arm
0.738 0.262 0.000
Z93.4 Other artificial openings of gastro-intestinal tract status
0.738 0.262 0.000
T90 Sequelae of injuries of head
0.737 0.262 0.000
G81.9 Hemiplegia, unspecified
0.737 0.263 0.000
D33 Benign neoplasm of brain and other parts of central nervous system
0.737 0.263 0.000
K85 Acute pancreatitis
0.737 0.263 0.000
M16.7 Other secondary coxarthrosis
0.736 0.264 0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.735 0.265 0.000
L03.1 Cellulitis of other parts of limb
0.735 0.265 0.000
C55 Malignant neoplasm of uterus, part unspecified
0.734 0.266 0.000
K57 Diverticular disease of intestine
0.734 0.266 0.000
G40 Epilepsy
0.734 0.266 0.000
K83.1 Obstruction of bile duct
0.733 0.267 0.000
J00-J06 Acute upper respiratory infections
0.733 0.267 0.000
K56.4 Other impaction of intestine
0.733 0.267 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.733 0.267 0.000
G45.8 Other transient cerebral ischaemic attacks and related syndromes
0.732 0.268 0.000
Z42 Follow-up care involving plastic surgery
0.732 0.268 0.000
N70.9 Salpingitis and oophoritis, unspecified
0.732 0.268 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.732 0.268 0.000
N82 Fistulae involving female genital tract
0.731 0.269 0.000
K58 Irritable bowel syndrome
0.730 0.270 0.000
M10 Gout
0.730 0.270 0.000
N97 Female infertility
0.730 0.270 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.729 0.271 0.000
K25 Gastric ulcer
0.728 0.272 0.000
J18.1 Lobar pneumonia, unspecified
0.728 0.272 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.727 0.272 0.000
D23.0 Skin of lip
0.727 0.272 0.000
I46.0 Cardiac arrest with successful resuscitation
0.726 0.274 0.000
T87 Complications peculiar to reattachment and amputation
0.726 0.274 0.000
N75 Diseases of Bartholin's gland
0.726 0.274 0.000
N88.8 Other specified noninflammatory disorders of cervix uteri
0.726 0.274 0.000
M21.6 Other acquired deformities of ankle and foot
0.725 0.275 0.000
Z53.8 Procedure not carried out for other reasons
0.725 0.275 0.000
E40-E46 Malnutrition
0.725 0.275 0.000
M76 Enthesopathies of lower limb, excluding foot
0.723 0.277 0.000
Z81 Family history of mental and behavioural disorders
0.722 0.278 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.722 0.278 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.722 0.278 0.000
R45.8 Other symptoms and signs involving emotional state
0.721 0.279 0.000
R41.0 Disorientation, unspecified
0.721 0.279 0.000
N80.9 Endometriosis, unspecified
0.720 0.280 0.000
G95 Other diseases of spinal cord
0.720 0.280 0.000
D37.2 Small intestine
0.720 0.280 0.000
Y57 Other and unspecified drugs and medicaments
0.720 0.280 0.000
K70.3 Alcoholic cirrhosis of liver
0.719 0.281 0.000
M34 Systemic sclerosis
0.718 0.281 0.000
H54.7 Unspecified visual loss
0.718 0.282 0.000
Z93.0 Tracheostomy status
0.718 0.282 0.000
M24.0 Loose body in joint
0.718 0.282 0.000
M79.2 Neuralgia and neuritis, unspecified
0.718 0.282 0.000
I51.8 Other ill-defined heart diseases
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
M91-M94 Chondropathies
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
M25.55 Pain in joint (Pelvic region and thigh)
0.717 0.283 0.000
D28 Benign neoplasm of other and unspecified female genital organs
0.717 0.283 0.000
K64 Haemorrhoids and perianal venous thrombosis
0.717 0.283 0.000
C80 Malignant neoplasm without specification of site
0.716 0.283 0.000
J11 Influenza, virus not identified
0.716 0.283 0.000
M89 Other disorders of bone
0.716 0.284 0.000
E04 Other non-toxic goitre
0.716 0.284 0.000
T93 Sequelae of injuries of lower limb
0.716 0.284 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.715 0.285 0.000
M33 Dermatopolymyositis
0.715 0.285 0.000
M32 Systemic lupus erythematosus
0.715 0.285 0.000
M30 Polyarteritis nodosa and related conditions
0.715 0.285 0.000
Z85.1 Personal history of malignant neoplasm of trachea, bronchus and lung
0.714 0.286 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.714 0.286 0.000
M21.07 Valgus deformity, not elsewhere classified (Ankle and foot)
0.714 0.286 0.000
G41 Status epilepticus
0.713 0.287 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.713 0.287 0.000
K86.8 Other specified diseases of pancreas
0.713 0.287 0.000
V80-V89 Other land transport accidents
0.713 0.287 0.000
Z84 Family history of other conditions
0.713 0.287 0.000
Z87.6 Personal history of certain conditions arising in the perinatal period
0.712 0.288 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.712 0.288 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.712 0.288 0.000
Y35-Y36 Legal intervention and operations of war
0.712 0.288 0.000
Y10-Y34 Event of undetermined intent
0.712 0.288 0.000
Y00-Y09 Assault
0.712 0.288 0.000
X85-X99 Assault
0.712 0.288 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.712 0.288 0.000
X50-X57 Overexertion, travel and privation
0.712 0.288 0.000
X30-X39 Exposure to forces of nature
0.712 0.288 0.000
X20-X29 Contact with venomous animals and plants
0.712 0.288 0.000
X10-X19 Contact with heat and hot substances
0.712 0.288 0.000
X00-X09 Exposure to smoke, fire and flames
0.712 0.288 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.712 0.288 0.000
W75-W84 Other accidental threats to breathing
0.712 0.288 0.000
W65-W74 Accidental drowning and submersion
0.712 0.288 0.000
W50-W64 Exposure to animate mechanical forces
0.712 0.288 0.000
V98-V99 Other and unspecified transport accidents
0.712 0.288 0.000
V95-V97 Air and space transport accidents
0.712 0.288 0.000
V90-V94 Water transport accidents
0.712 0.288 0.000
V70-V79 Bus occupant injured in transport accident
0.712 0.288 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.712 0.288 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.712 0.288 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.712 0.288 0.000
V01-V09 Pedestrian injured in transport accident
0.712 0.288 0.000
K55 Vascular disorders of intestine
0.712 0.288 0.000
C79.2 Secondary malignant neoplasm of skin
0.712 0.288 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.711 0.288 0.000
H02 Other disorders of eyelid
0.711 0.289 0.000
M25.9 Joint disorder, unspecified
0.711 0.289 0.000
M25.2 Flail joint
0.711 0.289 0.000
M25.1 Fistula of joint
0.711 0.289 0.000
M25.0 Haemarthrosis
0.711 0.289 0.000
H53.9 Visual disturbance, unspecified
0.711 0.289 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.711 0.289 0.000
Z90.7 Acquired absence of genital organ(s)
0.711 0.289 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.710 0.290 0.000
D31 Benign neoplasm of eye and adnexa
0.710 0.290 0.000
D30 Benign neoplasm of urinary organs
0.710 0.290 0.000
D29 Benign neoplasm of male genital organs
0.710 0.290 0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum
0.710 0.290 0.000
D19 Benign neoplasm of mesothelial tissue
0.710 0.290 0.000
D16 Benign neoplasm of bone and articular cartilage
0.710 0.290 0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs
0.710 0.290 0.000
D14 Benign neoplasm of middle ear and respiratory system
0.710 0.290 0.000
E67 Other hyperalimentation
0.710 0.290 0.000
E68 Sequelae of hyperalimentation
0.710 0.290 0.000
K60.1 Chronic anal fissure
0.710 0.290 0.000
K77 Liver disorders in diseases classified elsewhere
0.709 0.290 0.000
K71 Toxic liver disease
0.709 0.290 0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care
0.708 0.292 0.000
J95-J99 Other diseases of the respiratory system
0.708 0.292 0.000
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt
0.708 0.292 0.000
E66.2 Extreme obesity with alveolar hypoventilation
0.708 0.292 0.000
E66.1 Drug-induced obesity
0.708 0.292 0.000
E66.0 Obesity due to excess calories
0.708 0.292 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.707 0.293 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.707 0.293 0.000
Z50 Care involving use of rehabilitation procedures
0.706 0.294 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.706 0.294 0.000
M25.57 Pain in joint (Ankle and foot)
0.706 0.294 0.000
H54.0 Blindness, both eyes
0.705 0.295 0.000
Z93.5 Cystostomy status
0.705 0.295 0.000
M00-M03 Infectious arthropathies
0.705 0.295 0.000
D18 Haemangioma and lymphangioma, any site
0.705 0.295 0.000
N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.704 0.296 0.000
G83 Other paralytic syndromes
0.704 0.296 0.000
S32 Fracture of lumbar spine and pelvis
0.703 0.297 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.703 0.297 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.703 0.297 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.703 0.297 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.703 0.297 0.000
N74 Female pelvic inflammatory disorders in diseases classified elsewhere
0.703 0.297 0.000
V20-V29 Motorcycle rider injured in transport accident
0.702 0.298 0.000
L20-L30 Dermatitis and eczema
0.702 0.298 0.000
J92 Pleural plaque
0.701 0.299 0.000
E70-E90 Metabolic disorders
0.701 0.299 0.000
Z90.8 Acquired absence of other organs
0.701 0.299 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.701 0.299 0.000
Z96.2 Presence of otological and audiological implants
0.700 0.299 0.000
Z73.3 Stress, not elsewhere classified
0.700 0.300 0.000
M79.86 Other specified soft tissue disorders (Lower leg)
0.700 0.300 0.000
Y84.6 Urinary catheterisation
0.699 0.301 0.000
K72 Hepatic failure, not elsewhere classified
0.699 0.301 0.000
M25.78 Osteophyte (Other)
0.698 0.302 0.000
Z90.0 Acquired absence of part of head and neck
0.698 0.302 0.000
M21.2 Flexion deformity
0.698 0.302 0.000
K61.4 Intrasphincteric abscess
0.698 0.302 0.000
K61.2 Anorectal abscess
0.698 0.302 0.000
K61.1 Rectal abscess
0.698 0.302 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.698 0.302 0.000
R92 Abnormal findings on diagnostic imaging of breast
0.697 0.302 0.000
D37.6 Liver, gallbladder and bile ducts
0.697 0.303 0.000
D47.1 Chronic myeloproliferative disease
0.697 0.303 0.000
M24.2 Disorder of ligament
0.696 0.304 0.000
N98 Complications associated with artificial fertilisation
0.696 0.304 0.000
N91 Absent, scanty and rare menstruation
0.696 0.304 0.000
N96 Habitual aborter
0.696 0.304 0.000
T81.9 Unspecified complication of procedure
0.695 0.305 0.000
T81.7 Vascular complications following a procedure, not elsewhere classified
0.695 0.305 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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