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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs116434694
log Bayes Factor = 8.6061
Chromosome 1   position 203,335,188  (GRCh37) Explore rs116434694 on Ensembl!
Variant rs116434694 is part of Cluster X0052

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter VI Diseases of the nervous system
1.000 0.000 0.000
Chapter VII Diseases of the eye and adnexa
1.000 0.000 0.000
H30-H36 Disorders of choroid and retina
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
S00-S09 Injuries to the head
1.000 0.000 0.000
H33 Retinal detachments and breaks
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.999 0.001 0.000
E20-E35 Disorders of other endocrine glands
0.997 0.003 0.000
G40-G47 Episodic and paroxysmal disorders
0.997 0.003 0.000
H33.3 Retinal breaks without detachment
0.993 0.007 0.000
S00 Superficial injury of head
0.992 0.008 0.000
S00.8 Superficial injury of other parts of head
0.987 0.013 0.000
G40 Epilepsy
0.980 0.020 0.000
S02 Fracture of skull and facial bones
0.979 0.021 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.976 0.024 0.000
E10-E14 Diabetes mellitus
0.975 0.025 0.000
H43-H45 Disorders of vitreous body and globe
0.968 0.032 0.000
H33.2 Serous retinal detachment
0.968 0.032 0.000
E11 Non-insulin-dependent diabetes mellitus
0.967 0.033 0.000
H35 Other retinal disorders
0.962 0.038 0.000
G90-G99 Other disorders of the nervous system
0.959 0.041 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.955 0.045 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.952 0.048 0.000
H04 Disorders of lachrymal system
0.952 0.048 0.000
H43 Disorders of vitreous body
0.949 0.051 0.000
E27 Other disorders of adrenal gland
0.949 0.051 0.000
D50-D53 Nutritional anaemias
0.948 0.052 0.000
H04.2 Epiphora
0.948 0.052 0.000
D50 Iron deficiency anaemia
0.946 0.054 0.000
G44 Other headache syndromes
0.946 0.054 0.000
E11.4 With neurological complications
0.945 0.055 0.000
D50.8 Other iron deficiency anaemias
0.945 0.055 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.931 0.069 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.924 0.076 0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
0.923 0.077 0.000
E11.2 With renal complications
0.914 0.086 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.908 0.092 0.000
H43.1 Vitreous haemorrhage
0.908 0.092 0.000
H33.0 Retinal detachment with retinal break
0.906 0.094 0.000
S09 Other and unspecified injuries of head
0.905 0.095 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.903 0.097 0.000
G61 Inflammatory polyneuropathy
0.892 0.108 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.882 0.118 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.876 0.124 0.000
H43.8 Other disorders of vitreous body
0.875 0.125 0.000
G99.2 Myelopathy in diseases classified elsewhere
0.875 0.125 0.000
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)
0.873 0.127 0.000
Chapter XX External causes of morbidity and mortality
0.872 0.128 0.000
S05 Injury of eye and orbit
0.872 0.128 0.000
O26 Maternal care for other conditions predominantly related to pregnancy
0.869 0.131 0.000
S02.2 Fracture of nasal bones
0.866 0.134 0.000
Chapter I Certain infectious and parasitic diseases
0.866 0.134 0.000
O80-O84 Delivery
0.865 0.135 0.000
S06 Intracranial injury
0.856 0.144 0.000
E23 Hypofunction and other disorders of pituitary gland
0.853 0.147 0.000
G44.2 Tension-type headache
0.850 0.150 0.000
E29 Testicular dysfunction
0.849 0.151 0.000
S09.9 Unspecified injury of head
0.845 0.155 0.000
S02.5 Fracture of tooth
0.843 0.157 0.000
S02.3 Fracture of orbital floor
0.842 0.158 0.000
H35.8 Other specified retinal disorders
0.841 0.159 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.840 0.160 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.837 0.163 0.000
E28 Ovarian dysfunction
0.833 0.167 0.000
S40-S49 Injuries to the shoulder and upper arm
0.832 0.168 0.000
G60 Hereditary and idiopathic neuropathy
0.832 0.168 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.829 0.171 0.000
O80 Single spontaneous delivery
0.825 0.175 0.000
E27.1 Primary adrenocortical insufficiency
0.824 0.176 0.000
S02.1 Fracture of base of skull
0.823 0.177 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.820 0.180 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.818 0.182 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.815 0.185 0.000
E11.0 With coma
0.813 0.187 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.813 0.187 0.000
G70-G73 Diseases of myoneural junction and muscle
0.809 0.190 0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
0.808 0.192 0.000
E26 Hyperaldosteronism
0.806 0.194 0.000
G44.4 Drug-induced headache, not elsewhere classified
0.805 0.195 0.000
G82 Paraplegia and tetraplegia
0.805 0.195 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.803 0.197 0.000
H35.7 Separation of retinal layers
0.802 0.198 0.000
E34 Other endocrine disorders
0.801 0.198 0.000
S70-S79 Injuries to the hip and thigh
0.801 0.199 0.000
G62 Other polyneuropathies
0.801 0.199 0.000
O26.8 Other specified pregnancy-related conditions
0.797 0.203 0.000
H34 Retinal vascular occlusions
0.796 0.204 0.000
A00-A09 Intestinal infectious diseases
0.792 0.208 0.000
S00.9 Superficial injury of head, part unspecified
0.792 0.208 0.000
G99.0 Autonomic neuropathy in endocrine and metabolic diseases
0.791 0.209 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.787 0.213 0.000
E27.9 Disorder of adrenal gland, unspecified
0.786 0.214 0.000
S02.20 Fracture of nasal bones (closed)
0.785 0.215 0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)
0.785 0.215 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.785 0.215 0.000
H53-H54 Visual disturbances and blindness
0.785 0.215 0.000
G40.5 Special epileptic syndromes
0.783 0.217 0.000
S00.3 Superficial injury of nose
0.782 0.218 0.000
H35.6 Retinal haemorrhage
0.781 0.219 0.000
T79-T79 Certain early complications of trauma
0.781 0.219 0.000
O80.9 Single spontaneous delivery, unspecified
0.780 0.220 0.000
E22 Hyperfunction of pituitary gland
0.779 0.221 0.000
G45.4 Transient global amnesia
0.779 0.221 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.778 0.222 0.000
S20-S29 Injuries to the thorax
0.777 0.223 0.000
H04.8 Other disorders of lachrymal system
0.777 0.223 0.000
T23 Burn and corrosion of wrist and hand
0.775 0.225 0.000
O26.9 Pregnancy-related condition, unspecified
0.772 0.228 0.000
E40-E46 Malnutrition
0.768 0.232 0.000
H04.5 Stenosis and insufficiency of lachrymal passages
0.767 0.233 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.765 0.234 0.000
E11.3 With ophthalmic complications
0.765 0.235 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.765 0.235 0.000
G61.0 Guillain-Barre syndrome
0.763 0.237 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.763 0.237 0.000
E23.0 Hypopituitarism
0.763 0.237 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.762 0.238 0.000
G20-G26 Extrapyramidal and movement disorders
0.762 0.238 0.000
A04 Other bacterial intestinal infections
0.762 0.238 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.759 0.241 0.000
E10 Insulin-dependent diabetes mellitus
0.758 0.242 0.000
H33.4 Traction detachment of retina
0.757 0.243 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.756 0.244 0.000
E20 Hypoparathyroidism
0.756 0.244 0.000
B95-B98 Bacterial, viral and other infectious agents
0.754 0.246 0.000
G95 Other diseases of spinal cord
0.753 0.247 0.000
X50-X57 Overexertion, travel and privation
0.753 0.247 0.000
H35.4 Peripheral retinal degeneration
0.752 0.247 0.000
O85-O92 Complications predominantly related to the puerperium
0.752 0.248 0.000
H03 Disorders of eyelid in diseases classified elsewhere
0.751 0.249 0.000
S02.4 Fracture of malar and maxillary bones
0.751 0.249 0.000
G44.0 Cluster headache syndrome
0.750 0.250 0.000
H35.3 Degeneration of macula and posterior pole
0.748 0.252 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.748 0.252 0.000
H05 Disorders of orbit
0.747 0.253 0.000
G40.7 Petit mal, unspecified, without grand mal seizures
0.745 0.255 0.000
S02.50 Fracture of tooth (closed)
0.745 0.255 0.000
S02.30 Fracture of orbital floor (closed)
0.744 0.256 0.000
E29.1 Testicular hypofunction
0.742 0.258 0.000
G82.2 Paraplegia, unspecified
0.740 0.260 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.740 0.260 0.000
Chapter V Mental and behavioural disorders
0.739 0.261 0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes
0.738 0.262 0.000
G61.9 Inflammatory polyneuropathy, unspecified
0.736 0.264 0.000
E27.8 Other specified disorders of adrenal gland
0.736 0.264 0.000
A04.8 Other specified bacterial intestinal infections
0.735 0.265 0.000
H04.4 Chronic inflammation of lachrymal passages
0.735 0.265 0.000
S02.8 Fractures of other skull and facial bones
0.734 0.266 0.000
S10-S19 Injuries to the neck
0.732 0.267 0.000
T00-T07 Injuries involving multiple body regions
0.732 0.268 0.000
H35.0 Background retinopathy and retinal vascular changes
0.732 0.268 0.000
H54 Blindness and low vision
0.731 0.269 0.000
E24 Cushing's syndrome
0.731 0.269 0.000
T21 Burn and corrosion of trunk
0.730 0.270 0.000
G30-G32 Other degenerative diseases of the nervous system
0.729 0.271 0.000
T18 Foreign body in alimentary tract
0.727 0.273 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.726 0.274 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.724 0.276 0.000
G40.9 Epilepsy, unspecified
0.724 0.276 0.000
E27.2 Addisonian crisis
0.723 0.277 0.000
H33.1 Retinoschisis and retinal cysts
0.722 0.278 0.000
G60.8 Other hereditary and idiopathic neuropathies
0.722 0.278 0.000
H35.9 Retinal disorder, unspecified
0.720 0.279 0.000
D55-D59 Haemolytic anaemias
0.720 0.280 0.000
H18 Other disorders of cornea
0.719 0.281 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.717 0.283 0.000
H30 Chorioretinal inflammation
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
S32 Fracture of lumbar spine and pelvis
0.717 0.283 0.000
S08 Traumatic amputation of part of head
0.717 0.283 0.000
S07 Crushing injury of head
0.717 0.283 0.000
S04 Injury of cranial nerves
0.717 0.283 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.717 0.283 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.716 0.284 0.000
W50-W64 Exposure to animate mechanical forces
0.716 0.284 0.000
E28.2 Polycystic ovarian syndrome
0.715 0.285 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.715 0.285 0.000
E32 Diseases of thymus
0.715 0.285 0.000
E31 Polyglandular dysfunction
0.715 0.285 0.000
E30 Disorders of puberty, not elsewhere classified
0.715 0.285 0.000
E25 Adrenogenital disorders
0.715 0.285 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.714 0.285 0.000
H04.3 Acute and unspecified inflammation of lachrymal passages
0.714 0.286 0.000
G96 Other disorders of central nervous system
0.714 0.286 0.000
S02.10 Fracture of base of skull (closed)
0.712 0.288 0.000
S00.7 Multiple superficial injuries of head
0.711 0.289 0.000
S00.5 Superficial injury of lip and oral cavity
0.711 0.289 0.000
S00.4 Superficial injury of ear
0.711 0.289 0.000
S00.2 Other superficial injuries of eyelid and periocular area
0.711 0.289 0.000
H36 Retinal disorders in diseases classified elsewhere
0.710 0.290 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.708 0.292 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.708 0.292 0.000
E11.8 With unspecified complications
0.707 0.293 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.706 0.294 0.000
G41 Status epilepticus
0.706 0.294 0.000
O28 Abnormal findings on antenatal screening of mother
0.705 0.295 0.000
G40.8 Other epilepsy
0.703 0.297 0.000
G40.4 Other generalised epilepsy and epileptic syndromes
0.703 0.297 0.000
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset
0.703 0.297 0.000
S02.9 Fracture of skull and facial bones, part unspecified
0.702 0.298 0.000
S02.7 Multiple fractures involving skull and facial bones
0.702 0.298 0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand
0.701 0.299 0.000
G61.8 Other inflammatory polyneuropathies
0.701 0.299 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.701 0.299 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.701 0.299 0.000
E11.5 With peripheral circulatory complications
0.700 0.300 0.000
G64 Other disorders of peripheral nervous system
0.700 0.300 0.000
S06.3 Focal brain injury
0.699 0.300 0.000
E12 Malnutrition-related diabetes mellitus
0.699 0.301 0.000
X20-X29 Contact with venomous animals and plants
0.699 0.301 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.698 0.302 0.000
S05.9 Injury of eye and orbit, part unspecified
0.698 0.302 0.000
S05.1 Contusion of eyeball and orbital tissues
0.697 0.303 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.697 0.303 0.000
H31 Other disorders of choroid
0.696 0.303 0.000
S02.0 Fracture of vault of skull
0.696 0.304 0.000
S31 Open wound of abdomen, lower back and pelvis
0.696 0.304 0.000
G25 Other extrapyramidal and movement disorders
0.696 0.304 0.000
O24 Diabetes mellitus in pregnancy
0.695 0.305 0.000
D52 Folate deficiency anaemia
0.695 0.305 0.000
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.694 0.306 0.000
E11.7 With multiple complications
0.693 0.306 0.000
E11.1 With ketoacidosis
0.693 0.307 0.000
G83 Other paralytic syndromes
0.693 0.307 0.000
T85.1 Mechanical complication of implanted electronic stimulator of nervous system
0.692 0.308 0.000
E16 Other disorders of pancreatic internal secretion
0.691 0.308 0.000
G62.8 Other specified polyneuropathies
0.690 0.310 0.000
H35.1 Retinopathy of prematurity
0.689 0.310 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.688 0.312 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.688 0.312 0.000
G92 Toxic encephalopathy
0.688 0.312 0.000
E11.6 With other specified complications
0.686 0.314 0.000
G90 Disorders of autonomic nervous system
0.686 0.314 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.685 0.315 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.684 0.316 0.000
H04.9 Disorder of lachrymal system, unspecified
0.683 0.317 0.000
H04.6 Other changes in lachrymal passages
0.683 0.317 0.000
H04.0 Dacryoadenitis
0.683 0.317 0.000
O23 Infections of genito-urinary tract in pregnancy
0.683 0.317 0.000
G43 Migraine
0.683 0.317 0.000
E50-E64 Other nutritional deficiencies
0.682 0.318 0.000
O81 Single delivery by forceps and vacuum extractor
0.682 0.318 0.000
T14 Injury of unspecified body region
0.682 0.318 0.000
H43.9 Disorder of vitreous body, unspecified
0.680 0.320 0.000
H43.2 Crystalline deposits in vitreous body
0.680 0.320 0.000
H43.0 Vitreous prolapse
0.680 0.320 0.000
E27.5 Adrenomedullary hyperfunction
0.680 0.320 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.680 0.320 0.000
E27.0 Other adrenocortical overactivity
0.680 0.320 0.000
D53 Other nutritional anaemias
0.680 0.320 0.000
S90-S99 Injuries to the ankle and foot
0.680 0.320 0.000
T20 Burn and corrosion of head and neck
0.680 0.320 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.679 0.321 0.000
D50.1 Sideropenic dysphagia
0.679 0.321 0.000
G63.2 Diabetic polyneuropathy
0.678 0.321 0.000
G44.8 Other specified headache syndromes
0.678 0.322 0.000
G44.3 Chronic posttraumatic headache
0.678 0.322 0.000
G44.1 Vascular headache, not elsewhere classified
0.678 0.322 0.000
G71 Primary disorders of muscles
0.675 0.325 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.675 0.325 0.000
O80.0 Spontaneous vertex delivery
0.675 0.325 0.000
S06.0 Concussion
0.674 0.326 0.000
H34.2 Other retinal artery occlusions
0.671 0.329 0.000
B50-B64 Protozoal diseases
0.670 0.330 0.000
S05.0 Injury of conjunctiva and corneal abrasion without mention of foreign body
0.670 0.330 0.000
E26.0 Primary hyperaldosteronism
0.669 0.331 0.000
G47 Sleep disorders
0.665 0.335 0.000
S06.6 Traumatic subarachnoid haemorrhage
0.663 0.337 0.000
Y44 Agents primarily affecting blood constituents
0.663 0.337 0.000
G99.8 Other specified disorders of nervous system in diseases classified elsewhere
0.662 0.337 0.000
G99.1 Other disorders of autonomic nervous system in other diseases classified elsewhere
0.662 0.337 0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts
0.662 0.338 0.000
E34.0 Carcinoid syndrome
0.661 0.339 0.000
O20 Haemorrhage in early pregnancy
0.661 0.339 0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.659 0.341 0.000
H35.2 Other proliferative retinopathy
0.658 0.342 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.656 0.344 0.000
Y57 Other and unspecified drugs and medicaments
0.651 0.349 0.000
T25 Burn and corrosion of ankle and foot
0.651 0.349 0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot
0.651 0.349 0.000
E21.3 Hyperparathyroidism, unspecified
0.651 0.349 0.000
O26.7 Subluxation of symphysis (pubis) in pregnancy, childbirth and the puerperium
0.650 0.350 0.000
G80 Infantile cerebral palsy
0.649 0.351 0.000
S42 Fracture of shoulder and upper arm
0.649 0.351 0.000
S09.7 Multiple injuries of head
0.648 0.351 0.000
S09.2 Traumatic rupture of ear drum
0.648 0.351 0.000
S09.1 Injury of muscle and tendon of head
0.648 0.351 0.000
S09.0 Injury of blood vessels of head, not elsewhere classified
0.648 0.351 0.000
O29 Complications of anaesthesia during pregnancy
0.648 0.352 0.000
O22 Venous complications in pregnancy
0.648 0.352 0.000
O25 Malnutrition in pregnancy
0.648 0.352 0.000
S05.8 Other injuries of eye and orbit
0.647 0.353 0.000
H35.5 Hereditary retinal dystrophy
0.646 0.354 0.000
S06.4 Epidural haemorrhage
0.646 0.354 0.000
Y52 Agents primarily affecting the cardiovascular system
0.646 0.354 0.000
S06.8 Other intracranial injuries
0.646 0.354 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.645 0.355 0.000
X50 Overexertion and strenuous or repetitive movements
0.645 0.355 0.000
H54.0 Blindness, both eyes
0.645 0.355 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.644 0.355 0.000
G82.1 Spastic paraplegia
0.644 0.356 0.000
V80-V89 Other land transport accidents
0.643 0.357 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.643 0.357 0.000
H44 Disorders of globe
0.642 0.357 0.000
D51 Vitamin B12 deficiency anaemia
0.641 0.359 0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis
0.640 0.360 0.000
G61.1 Serum neuropathy
0.639 0.360 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.638 0.362 0.000
G25.8 Other specified extrapyramidal and movement disorders
0.636 0.364 0.000
S79 Other and unspecified injuries of hip and thigh
0.635 0.365 0.000
O26.2 Pregnancy care of habitual aborter
0.635 0.365 0.000
G72 Other myopathies
0.634 0.366 0.000
X10-X19 Contact with heat and hot substances
0.633 0.367 0.000
H33.5 Other retinal detachments
0.631 0.369 0.000
T18.1 Foreign body in oesophagus
0.630 0.370 0.000
H54.4 Blindness, one eye
0.629 0.370 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.629 0.371 0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis
0.628 0.372 0.000
S37 Injury of urinary and pelvic organs
0.628 0.372 0.000
S36 Injury of intra-abdominal organs
0.628 0.372 0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level
0.628 0.372 0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level
0.628 0.372 0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis
0.628 0.372 0.000
G59.0 Diabetic mononeuropathy
0.628 0.372 0.000
S41 Open wound of shoulder and upper arm
0.628 0.372 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.628 0.372 0.000
S30.0 Contusion of lower back and pelvis
0.627 0.373 0.000
O90 Complications of the puerperium, not elsewhere classified
0.627 0.373 0.000
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters
0.626 0.374 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.626 0.374 0.000
Y35-Y36 Legal intervention and operations of war
0.625 0.374 0.000
Y10-Y34 Event of undetermined intent
0.625 0.374 0.000
Y00-Y09 Assault
0.625 0.374 0.000
X85-X99 Assault
0.625 0.374 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.625 0.374 0.000
X30-X39 Exposure to forces of nature
0.625 0.374 0.000
X00-X09 Exposure to smoke, fire and flames
0.625 0.374 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.625 0.374 0.000
W75-W84 Other accidental threats to breathing
0.625 0.374 0.000
W65-W74 Accidental drowning and submersion
0.625 0.374 0.000
V98-V99 Other and unspecified transport accidents
0.625 0.374 0.000
V95-V97 Air and space transport accidents
0.625 0.374 0.000
V90-V94 Water transport accidents
0.625 0.374 0.000
V70-V79 Bus occupant injured in transport accident
0.625 0.374 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.625 0.374 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.625 0.374 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.625 0.374 0.000
V01-V09 Pedestrian injured in transport accident
0.625 0.374 0.000
S05.7 Avulsion of eye
0.625 0.375 0.000
S05.6 Penetrating wound of eyeball without foreign body
0.625 0.375 0.000
S05.5 Penetrating wound of eyeball with foreign body
0.625 0.375 0.000
S05.4 Penetrating wound of orbit with or without foreign body
0.625 0.375 0.000
S05.3 Ocular laceration without prolapse or loss of intraocular tissue
0.625 0.375 0.000
S05.2 Ocular laceration and rupture with prolapse or loss of intraocular tissue
0.625 0.375 0.000
B65-B83 Helminthiases
0.625 0.375 0.000
G54 Nerve root and plexus disorders
0.624 0.376 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.624 0.376 0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.623 0.377 0.000
O26.6 Liver disorders in pregnancy, childbirth and the puerperium
0.623 0.377 0.000
O26.5 Maternal hypotension syndrome
0.623 0.377 0.000
O26.4 Herpes gestationis
0.623 0.377 0.000
O26.3 Retained intra-uterine contraceptive device in pregnancy
0.623 0.377 0.000
O26.1 Low weight gain in pregnancy
0.623 0.377 0.000
O26.0 Excessive weight gain in pregnancy
0.623 0.377 0.000
S02.6 Fracture of mandible
0.622 0.377 0.000
O21 Excessive vomiting in pregnancy
0.622 0.378 0.000
V40-V49 Car occupant injured in transport accident
0.622 0.378 0.000
T63 Toxic effect of contact with venomous animals
0.621 0.379 0.000
H43.3 Other vitreous opacities
0.621 0.379 0.000
S02.21 Fracture of nasal bones (open)
0.621 0.379 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.621 0.379 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.621 0.379 0.000
A75-A79 Rickettsioses
0.621 0.379 0.000
A70-A74 Other diseases caused by chlamydiae
0.621 0.379 0.000
A65-A69 Other spirochaetal diseases
0.621 0.379 0.000
A20-A28 Certain zoonotic bacterial diseases
0.621 0.379 0.000
A15-A19 Tuberculosis
0.621 0.379 0.000
G45.8 Other transient cerebral ischaemic attacks and related syndromes
0.621 0.379 0.000
O84 Multiple delivery
0.620 0.379 0.000
O83 Other assisted single delivery
0.620 0.379 0.000
H16 Keratitis
0.619 0.381 0.000
S49.9 Unspecified injury of shoulder and upper arm
0.619 0.381 0.000
T23.2 Burn of second degree of wrist and hand
0.619 0.381 0.000
G30 Alzheimer's disease
0.617 0.383 0.000
S06.2 Diffuse brain injury
0.616 0.384 0.000
H18.5 Hereditary corneal dystrophies
0.616 0.384 0.000
S06.9 Intracranial injury, unspecified
0.614 0.386 0.000
S06.7 Intracranial injury with prolonged coma
0.614 0.386 0.000
S06.1 Traumatic cerebral oedema
0.614 0.386 0.000
G95.2 Cord compression, unspecified
0.612 0.388 0.000
E23.7 Disorder of pituitary gland, unspecified
0.612 0.388 0.000
E23.6 Other disorders of pituitary gland
0.612 0.388 0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.612 0.388 0.000
E23.1 Drug-induced hypopituitarism
0.612 0.388 0.000
S09.8 Other specified injuries of head
0.612 0.388 0.000
X60-X84 Intentional self-harm
0.611 0.389 0.000
G60.0 Hereditary motor and sensory neuropathy
0.610 0.390 0.000
T59 Toxic effect of other gases, fumes and vapours
0.610 0.390 0.000
S32.0 Fracture of lumbar vertebra
0.609 0.391 0.000
S40 Superficial injury of shoulder and upper arm
0.609 0.391 0.000
S30.8 Other superficial injuries of abdomen, lower back and pelvis
0.609 0.391 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.609 0.391 0.000
E29.9 Testicular dysfunction, unspecified
0.608 0.391 0.000
E29.8 Other testicular dysfunction
0.608 0.391 0.000
E29.0 Testicular hyperfunction
0.608 0.391 0.000
Chapter XXII Codes for special purposes
0.608 0.392 0.000
A02 Other Salmonella infections
0.607 0.393 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.607 0.393 0.000
H03.1 Involvement of eyelid in other infectious diseases classified elsewhere
0.606 0.394 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.605 0.395 0.000
T23.0 Burn of unspecified degree of wrist and hand
0.605 0.395 0.000
S02.51 Fracture of tooth (open)
0.604 0.396 0.000
S02.31 Fracture of orbital floor (open)
0.604 0.396 0.000
E13 Other specified diabetes mellitus
0.603 0.396 0.000
H17 Corneal scars and opacities
0.603 0.397 0.000
W55 Bitten or struck by other mammals
0.603 0.397 0.000
E46 Unspecified protein-energy malnutrition
0.603 0.397 0.000
T19 Foreign body in genito-urinary tract
0.602 0.397 0.000
T15 Foreign body on external eye
0.602 0.397 0.000
T16 Foreign body in ear
0.602 0.397 0.000
T23.3 Burn of third degree of wrist and hand
0.602 0.397 0.000
G45.3 Amaurosis fugax
0.602 0.398 0.000
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters
0.602 0.398 0.000
T17 Foreign body in respiratory tract
0.601 0.399 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.601 0.399 0.000
T87 Complications peculiar to reattachment and amputation
0.600 0.400 0.000
T58 Toxic effect of carbon monoxide
0.598 0.402 0.000
G04 Encephalitis, myelitis and encephalomyelitis
0.597 0.402 0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.597 0.403 0.000
E28.9 Ovarian dysfunction, unspecified
0.597 0.403 0.000
E28.8 Other ovarian dysfunction
0.597 0.403 0.000
E28.3 Primary ovarian failure
0.597 0.403 0.000
E28.1 Androgen excess
0.597 0.403 0.000
E28.0 Oestrogen excess
0.597 0.403 0.000
S48 Traumatic amputation of shoulder and upper arm
0.597 0.403 0.000
S45 Injury of blood vessels at shoulder and upper arm level
0.597 0.403 0.000
S44 Injury of nerves at shoulder and upper arm level
0.597 0.403 0.000
S47 Crushing injury of shoulder and upper arm
0.597 0.403 0.000
G62.0 Drug-induced polyneuropathy
0.597 0.403 0.000
W20-W49 Exposure to inanimate mechanical forces
0.597 0.403 0.000
G60.9 Hereditary and idiopathic neuropathy, unspecified
0.596 0.403 0.000
G60.3 Idiopathic progressive neuropathy
0.596 0.403 0.000
G60.2 Neuropathy in association with hereditary ataxia
0.596 0.403 0.000
G60.1 Refsum's disease
0.596 0.403 0.000
S27 Injury of other and unspecified intrathoracic organs
0.596 0.404 0.000
T88.5 Other complications of anaesthesia
0.596 0.404 0.000
S00.1 Contusion of eyelid and periocular area
0.595 0.405 0.000
T88.7 Unspecified adverse effect of drug or medicament
0.595 0.405 0.000
G45.2 Multiple and bilateral precerebral artery syndromes
0.594 0.405 0.000
G45.1 Carotid artery syndrome (hemispheric)
0.594 0.405 0.000
G45.0 Vertebro-basilar artery syndrome
0.594 0.405 0.000
G97.0 Cerebrospinal fluid leak from spinal puncture
0.594 0.406 0.000
S72 Fracture of femur
0.594 0.406 0.000
G58 Other mononeuropathies
0.594 0.406 0.000
E10.5 With peripheral circulatory complications
0.593 0.407 0.000
S32.8 Fracture of other and unspecified parts of lumbar spine and pelvis
0.593 0.407 0.000
O80.8 Other single spontaneous delivery
0.591 0.408 0.000
O80.1 Spontaneous breech delivery
0.591 0.408 0.000
F10.1 Harmful use
0.591 0.409 0.000
H21 Other disorders of iris and ciliary body
0.591 0.409 0.000
S02.11 Fracture of base of skull (open)
0.590 0.409 0.000
S70 Superficial injury of hip and thigh
0.590 0.410 0.000
D69 Purpura and other haemorrhagic conditions
0.590 0.410 0.000
E22.1 Hyperprolactinaemia
0.590 0.410 0.000
A07 Other protozoal intestinal diseases
0.590 0.410 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.590 0.410 0.000
Y43 Primarily systemic agents
0.590 0.410 0.000
H05.8 Other disorders of orbit
0.589 0.411 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.589 0.411 0.000
E15 Nondiabetic hypoglycaemic coma
0.588 0.412 0.000
S02.40 Fracture of malar and maxillary bones (closed)
0.588 0.412 0.000
G97.8 Other postprocedural disorders of nervous system
0.587 0.413 0.000
S06.30 Focal brain injury (without open intracranial wound)
0.587 0.413 0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere
0.586 0.413 0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere
0.586 0.413 0.000
H15 Disorders of sclera
0.586 0.413 0.000
E16.1 Other hypoglycaemia
0.585 0.415 0.000
W00-W19 Falls
0.584 0.416 0.000
T13 Other injuries of lower limb, level unspecified
0.584 0.416 0.000
T11 Other injuries of upper limb, level unspecified
0.584 0.416 0.000
T09 Other injuries of spine and trunk, level unspecified
0.584 0.416 0.000
T12.X1 Fracture of lower limb, level unspecified (open)
0.584 0.416 0.000
T12.X0 Fracture of lower limb, level unspecified (closed)
0.584 0.416 0.000
T12 Fracture of lower limb, level unspecified
0.584 0.416 0.000
T10.X1 Fracture of upper limb, level unspecified (open)
0.584 0.416 0.000
T10.X0 Fracture of upper limb, level unspecified (closed)
0.584 0.416 0.000
T10 Fracture of upper limb, level unspecified
0.584 0.416 0.000
T08.X1 Fracture of spine, level unspecified (open)
0.584 0.416 0.000
T08.X0 Fracture of spine, level unspecified (closed)
0.584 0.416 0.000
T08 Fracture of spine, level unspecified
0.584 0.416 0.000
F99-F99 Unspecified mental disorder
0.584 0.416 0.000
X51 Travel and motion
0.584 0.416 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.583 0.417 0.000
E20.9 Hypoparathyroidism, unspecified
0.583 0.417 0.000
E21.5 Disorder of parathyroid gland, unspecified
0.583 0.417 0.000
E21.4 Other specified disorders of parathyroid gland
0.583 0.417 0.000
E21.2 Other hyperparathyroidism
0.583 0.417 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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