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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs116859464
log Bayes Factor = 15.7364
Chromosome 7   position 156,086,970  (GRCh37) Explore rs116859464 on Ensembl!
Variant rs116859464 is part of Cluster X0059

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter II Neoplasms
0.999 0.001 0.000
Chapter VII Diseases of the eye and adnexa
0.999 0.001 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.999 0.001 0.000
M45-M49 Spondylopathies
0.998 0.002 0.000
H30-H36 Disorders of choroid and retina
0.996 0.004 0.000
M47 Spondylosis
0.995 0.005 0.000
Chapter XXI Factors influencing health status and contact with health services
0.993 0.007 0.000
C60-C63 Malignant neoplasms of male genital organs
0.991 0.009 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.991 0.009 0.000
C61 Malignant neoplasm of prostate
0.986 0.014 0.000
M05-M14 Inflammatory polyarthropathies
0.986 0.014 0.000
E70-E90 Metabolic disorders
0.985 0.015 0.000
Chapter IX Diseases of the circulatory system
0.983 0.017 0.000
M47.8 Other spondylosis
0.980 0.020 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.978 0.022 0.000
M50-M54 Other dorsopathies
0.977 0.023 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.976 0.024 0.000
M06 Other rheumatoid arthritis
0.975 0.025 0.000
Chapter VI Diseases of the nervous system
0.968 0.032 0.000
M06.9 Rheumatoid arthritis, unspecified
0.966 0.034 0.000
H35 Other retinal disorders
0.964 0.036 0.000
M15-M19 Arthrosis
0.962 0.038 0.000
E10-E14 Diabetes mellitus
0.961 0.039 0.000
E86 Volume depletion
0.957 0.043 0.000
M47.86 Other spondylosis (Lumbar region)
0.952 0.048 0.000
H33 Retinal detachments and breaks
0.952 0.048 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.952 0.048 0.000
M70-M79 Other soft tissue disorders
0.945 0.055 0.000
M19 Other arthrosis
0.942 0.058 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.941 0.059 0.000
Z72 Problems related to lifestyle
0.938 0.062 0.000
D00-D09 In situ neoplasms
0.938 0.062 0.000
R79 Other abnormal findings of blood chemistry
0.934 0.066 0.000
M19.9 Arthrosis, unspecified
0.928 0.072 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.928 0.072 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.923 0.077 0.000
R79.8 Other specified abnormal findings of blood chemistry
0.923 0.077 0.000
H10-H13 Disorders of conjunctiva
0.922 0.078 0.000
M47.9 Spondylosis, unspecified
0.922 0.078 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.918 0.082 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.915 0.085 0.000
C79 Secondary malignant neoplasm of other sites
0.915 0.085 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.914 0.086 0.000
Chapter I Certain infectious and parasitic diseases
0.911 0.089 0.000
I10-I15 Hypertensive diseases
0.910 0.090 0.000
Chapter V Mental and behavioural disorders
0.909 0.091 0.000
E11 Non-insulin-dependent diabetes mellitus
0.908 0.092 0.000
H35.8 Other specified retinal disorders
0.907 0.093 0.000
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms
0.901 0.099 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.901 0.099 0.000
S00-S09 Injuries to the head
0.896 0.104 0.000
Chapter XX External causes of morbidity and mortality
0.895 0.105 0.000
I05-I09 Chronic rheumatic heart diseases
0.895 0.105 0.000
H34 Retinal vascular occlusions
0.893 0.107 0.000
G20-G26 Extrapyramidal and movement disorders
0.890 0.110 0.000
R26 Abnormalities of gait and mobility
0.889 0.111 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.889 0.111 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.887 0.113 0.000
G30-G32 Other degenerative diseases of the nervous system
0.885 0.115 0.000
M54 Dorsalgia
0.885 0.115 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.884 0.116 0.000
Z09.8 Follow-up examination after other treatment for other conditions
0.880 0.120 0.000
M19.97 Arthrosis, unspecified (Ankle and foot)
0.880 0.120 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.877 0.123 0.000
Z72.0 Tobacco use
0.874 0.126 0.000
E83 Disorders of mineral metabolism
0.873 0.127 0.000
M47.96 Spondylosis, unspecified (Lumbar region)
0.869 0.131 0.000
R26.8 Other and unspecified abnormalities of gait and mobility
0.863 0.137 0.000
I10 Essential (primary) hypertension
0.861 0.139 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.861 0.139 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.860 0.140 0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis
0.859 0.141 0.000
H11 Other disorders of conjunctiva
0.855 0.145 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.853 0.147 0.000
M47.2 Other spondylosis with radiculopathy
0.852 0.148 0.000
H43-H45 Disorders of vitreous body and globe
0.846 0.154 0.000
D03 Melanoma in situ
0.842 0.158 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.842 0.158 0.000
S80-S89 Injuries to the knee and lower leg
0.839 0.161 0.000
M80-M85 Disorders of bone density and structure
0.838 0.162 0.000
H33.3 Retinal breaks without detachment
0.832 0.167 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.831 0.169 0.000
R87 Abnormal findings in specimens from female genital organs
0.831 0.169 0.000
H33.0 Retinal detachment with retinal break
0.831 0.169 0.000
M53 Other dorsopathies, not elsewhere classified
0.829 0.171 0.000
M79.0 Rheumatism, unspecified
0.829 0.171 0.000
S40-S49 Injuries to the shoulder and upper arm
0.828 0.172 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.827 0.173 0.000
I71 Aortic aneurysm and dissection
0.826 0.174 0.000
M47.80 Other spondylosis (Multiple sites in spine)
0.825 0.174 0.000
H55-H59 Other disorders of eye and adnexa
0.825 0.175 0.000
M51 Other intervertebral disk disorders
0.823 0.177 0.000
G70-G73 Diseases of myoneural junction and muscle
0.819 0.181 0.000
Z72.1 Alcohol use
0.819 0.181 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.819 0.181 0.000
S60-S69 Injuries to the wrist and hand
0.819 0.181 0.000
S09 Other and unspecified injuries of head
0.816 0.184 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.816 0.184 0.000
I08 Multiple valve diseases
0.815 0.185 0.000
Z09.2 Follow-up examination after chemotherapy for other conditions
0.815 0.185 0.000
M79.6 Pain in limb
0.814 0.186 0.000
I20-I25 Ischaemic heart diseases
0.812 0.188 0.000
A00-A09 Intestinal infectious diseases
0.812 0.188 0.000
G90-G99 Other disorders of the nervous system
0.812 0.188 0.000
M46 Other inflammatory spondylopathies
0.807 0.193 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.807 0.193 0.000
M50 Cervical disk disorders
0.806 0.194 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.805 0.194 0.000
M47.82 Other spondylosis (Cervical region)
0.805 0.195 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.803 0.197 0.000
E20-E35 Disorders of other endocrine glands
0.802 0.198 0.000
M91-M94 Chondropathies
0.801 0.199 0.000
H35.0 Background retinopathy and retinal vascular changes
0.801 0.199 0.000
M86-M90 Other osteopathies
0.800 0.200 0.000
E10 Insulin-dependent diabetes mellitus
0.798 0.202 0.000
H33.2 Serous retinal detachment
0.796 0.204 0.000
S70-S79 Injuries to the hip and thigh
0.795 0.205 0.000
Z75 Problems related to medical facilities and other health care
0.794 0.206 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.794 0.206 0.000
G30 Alzheimer's disease
0.794 0.206 0.000
R87.6 Abnormal cytological findings
0.793 0.207 0.000
H35.4 Peripheral retinal degeneration
0.792 0.207 0.000
E11.4 With neurological complications
0.791 0.209 0.000
E50-E64 Other nutritional deficiencies
0.790 0.210 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.789 0.211 0.000
M07 Psoriatic and enteropathic arthropathies
0.788 0.212 0.000
E83.1 Disorders of iron metabolism
0.787 0.213 0.000
M20-M25 Other joint disorders
0.787 0.213 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.786 0.214 0.000
Z13 Special screening examination for other diseases and disorders
0.785 0.215 0.000
C78.0 Secondary malignant neoplasm of lung
0.784 0.216 0.000
M79.7 Fibromyalgia
0.783 0.217 0.000
R79.0 Abnormal level of blood mineral
0.783 0.217 0.000
M19.92 Arthrosis, unspecified (Upper arm)
0.782 0.217 0.000
D04 Carcinoma in situ of skin
0.782 0.218 0.000
M19.94 Arthrosis, unspecified (Hand)
0.781 0.219 0.000
D05 Carcinoma in situ of breast
0.780 0.220 0.000
M48 Other spondylopathies
0.776 0.224 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.775 0.225 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.775 0.225 0.000
G25 Other extrapyramidal and movement disorders
0.775 0.225 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.775 0.225 0.000
E11.5 With peripheral circulatory complications
0.772 0.228 0.000
C15-C26 Malignant neoplasms of digestive organs
0.770 0.230 0.000
M18 Arthrosis of first carpometacarpal joint
0.769 0.231 0.000
Z53 Persons encountering health services for specifie procedures, not carried out
0.769 0.231 0.000
G20 Parkinson's disease
0.768 0.232 0.000
T66-T78 Other and unspecified effects of external causes
0.764 0.236 0.000
S90-S99 Injuries to the ankle and foot
0.764 0.236 0.000
H34.8 Other retinal vascular occlusions
0.762 0.237 0.000
M19.93 Arthrosis, unspecified (Forearm)
0.762 0.238 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.761 0.239 0.000
C34 Malignant neoplasm of bronchus and lung
0.760 0.240 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.760 0.240 0.000
M05 Seropositive rheumatoid arthritis
0.760 0.240 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.759 0.241 0.000
S09.9 Unspecified injury of head
0.759 0.241 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.756 0.244 0.000
I30-I52 Other forms of heart disease
0.756 0.244 0.000
S10-S19 Injuries to the neck
0.754 0.246 0.000
Z76 Persons encountering health services in other circumstances
0.754 0.246 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.754 0.246 0.000
T79-T79 Certain early complications of trauma
0.753 0.246 0.000
M19.91 Arthrosis, unspecified (Shoulder region)
0.752 0.248 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.751 0.249 0.000
M54.9 Dorsalgia, unspecified
0.749 0.251 0.000
H34.2 Other retinal artery occlusions
0.749 0.251 0.000
Z63 Other problems related to primary support group, including family circumstances
0.749 0.251 0.000
G57 Mononeuropathies of lower limb
0.748 0.252 0.000
I08.1 Disorders of both mitral and tricuspid valves
0.746 0.254 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.746 0.254 0.000
R25 Abnormal involuntary movements
0.745 0.255 0.000
M06.0 Seronegative rheumatoid arthritis
0.744 0.256 0.000
Z01.5 Diagnostic skin and sensitisation tests
0.742 0.258 0.000
M54.4 Lumbago with sciatica
0.742 0.258 0.000
H11.4 Other conjunctival vascular disorders and cysts
0.741 0.259 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.740 0.260 0.000
H11.3 Conjunctival haemorrhage
0.740 0.260 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.740 0.260 0.000
Z53.0 Procedure not carried out because of contraindication
0.740 0.260 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.739 0.261 0.000
Z53.8 Procedure not carried out for other reasons
0.739 0.261 0.000
E88 Other metabolic disorders
0.739 0.261 0.000
Chapter XXII Codes for special purposes
0.739 0.261 0.000
E87.5 Hyperkalaemia
0.738 0.262 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.737 0.263 0.000
G58 Other mononeuropathies
0.737 0.263 0.000
W20-W49 Exposure to inanimate mechanical forces
0.737 0.263 0.000
M76 Enthesopathies of lower limb, excluding foot
0.736 0.264 0.000
H43 Disorders of vitreous body
0.735 0.265 0.000
M81 Osteoporosis without pathological fracture
0.734 0.266 0.000
M16 Coxarthrosis [arthrosis of hip]
0.731 0.269 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.730 0.270 0.000
Z71.1 Person with feared complaint in whom no diagnosis is made
0.730 0.270 0.000
M79.09 Rheumatism, unspecified (Site unspecified)
0.729 0.271 0.000
R79.9 Abnormal finding of blood chemistry, unspecified
0.728 0.272 0.000
G30.9 Alzheimer's disease, unspecified
0.728 0.272 0.000
Z71.3 Dietary counselling and surveillance
0.728 0.272 0.000
A30-A49 Other bacterial diseases
0.727 0.273 0.000
M45 Ankylosing spondylitis
0.727 0.273 0.000
S89 Other and unspecified injuries of lower leg
0.727 0.273 0.000
H53-H54 Visual disturbances and blindness
0.727 0.273 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.725 0.275 0.000
E14 Unspecified diabetes mellitus
0.725 0.275 0.000
E11.2 With renal complications
0.724 0.275 0.000
H35.9 Retinal disorder, unspecified
0.724 0.276 0.000
Z71.8 Other specified counselling
0.724 0.276 0.000
M54.5 Low back pain
0.724 0.276 0.000
M53.3 Sacrococcygeal disorders, not elsewhere classified
0.723 0.276 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.723 0.277 0.000
M47.90 Spondylosis, unspecified (Multiple sites in spine)
0.723 0.277 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.719 0.281 0.000
M19.1 Posttraumatic arthrosis of other joints
0.719 0.281 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.718 0.281 0.000
M47.99 Spondylosis, unspecified (Site unspecified)
0.718 0.282 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
F00 Dementia in Alzheimer's disease
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.716 0.284 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.716 0.284 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.716 0.284 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.716 0.284 0.000
B25-B34 Other viral diseases
0.716 0.284 0.000
M49 Spondylopathies in diseases classified elsewhere
0.715 0.284 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.715 0.285 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.715 0.285 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.715 0.285 0.000
F20 Schizophrenia
0.714 0.286 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.714 0.286 0.000
H31 Other disorders of choroid
0.714 0.286 0.000
H30 Chorioretinal inflammation
0.714 0.286 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.714 0.286 0.000
M47.1 Other spondylosis with myelopathy
0.713 0.286 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.713 0.286 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.713 0.287 0.000
E40-E46 Malnutrition
0.712 0.287 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.712 0.288 0.000
B15-B19 Viral hepatitis
0.712 0.288 0.000
C63 Malignant neoplasm of other and unspecified male genital organs
0.711 0.289 0.000
C60 Malignant neoplasm of penis
0.711 0.289 0.000
T33-T35 Frostbite
0.710 0.290 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.710 0.290 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.710 0.290 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.710 0.290 0.000
T00-T07 Injuries involving multiple body regions
0.710 0.290 0.000
F29 Unspecified nonorganic psychosis
0.710 0.290 0.000
R72 Abnormality of white blood cells, not elsewhere classified
0.710 0.290 0.000
H10 Conjunctivitis
0.708 0.292 0.000
M54.6 Pain in thoracic spine
0.708 0.292 0.000
R26.2 Difficulty in walking, not elsewhere classified
0.707 0.293 0.000
M14 Arthropathies in other diseases classified elsewhere
0.707 0.293 0.000
M12 Other specific arthropathies
0.707 0.293 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.707 0.293 0.000
M08 Juvenile arthritis
0.707 0.293 0.000
E00-E07 Disorders of thyroid gland
0.707 0.293 0.000
E85 Amyloidosis
0.706 0.294 0.000
E84 Cystic fibrosis
0.706 0.294 0.000
E79 Disorders of purine and pyrimidine metabolism
0.706 0.294 0.000
E77 Disorders of glycoprotein metabolism
0.706 0.294 0.000
E76 Disorders of glycosaminoglycan metabolism
0.706 0.294 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.706 0.294 0.000
E74 Other disorders of carbohydrate metabolism
0.706 0.294 0.000
E73 Lactose intolerance
0.706 0.294 0.000
E72 Other disorders of amino-acid metabolism
0.706 0.294 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.706 0.294 0.000
E70 Disorders of aromatic amino-acid metabolism
0.706 0.294 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.706 0.294 0.000
M71 Other bursopathies
0.705 0.295 0.000
I00-I02 Acute rheumatic fever
0.705 0.295 0.000
I11 Hypertensive heart disease
0.704 0.296 0.000
M47.89 Other spondylosis (Site unspecified)
0.702 0.297 0.000
M47.88 Other spondylosis (Sacral and sacrococcygeal region)
0.702 0.297 0.000
M47.85 Other spondylosis (Thoracolumbar region)
0.702 0.297 0.000
M47.84 Other spondylosis (Thoracic region)
0.702 0.297 0.000
M47.83 Other spondylosis (Cervicothoracic region)
0.702 0.297 0.000
M47.81 Other spondylosis (Occipito-atlanto-axial region)
0.702 0.297 0.000
M50.3 Other cervical disk degeneration
0.702 0.298 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.702 0.298 0.000
Z70 Counselling related to sexual attitude, behaviour and orientation
0.701 0.298 0.000
C80 Malignant neoplasm without specification of site
0.700 0.300 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.700 0.300 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.700 0.300 0.000
S00 Superficial injury of head
0.699 0.301 0.000
Z01.6 Radiological examination, not elsewhere classified
0.699 0.301 0.000
S01 Open wound of head
0.699 0.301 0.000
M06.8 Other specified rheumatoid arthritis
0.699 0.301 0.000
M06.4 Inflammatory polyarthropathy
0.699 0.301 0.000
M06.3 Rheumatoid nodule
0.699 0.301 0.000
M06.2 Rheumatoid bursitis
0.699 0.301 0.000
M06.1 Adult-onset Still's disease
0.699 0.301 0.000
M19.98 Arthrosis, unspecified (Other)
0.698 0.302 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.698 0.302 0.000
D03.3 Melanoma in situ of other and unspecified parts of face
0.697 0.302 0.000
S20-S29 Injuries to the thorax
0.696 0.304 0.000
I05 Rheumatic mitral valve diseases
0.696 0.304 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.695 0.305 0.000
M47.22 Other spondylosis with radiculopathy (Cervical region)
0.695 0.305 0.000
D03.7 Melanoma in situ of lower limb, including hip
0.694 0.306 0.000
M47.26 Other spondylosis with radiculopathy (Lumbar region)
0.694 0.306 0.000
I21 Acute myocardial infarction
0.693 0.307 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.692 0.308 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.692 0.308 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.692 0.308 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.692 0.308 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.692 0.308 0.000
I73 Other peripheral vascular diseases
0.692 0.308 0.000
C77.3 Axillary and upper limb lymph nodes
0.692 0.308 0.000
H35.7 Separation of retinal layers
0.691 0.309 0.000
H35.6 Retinal haemorrhage
0.691 0.309 0.000
H35.5 Hereditary retinal dystrophy
0.691 0.309 0.000
H35.2 Other proliferative retinopathy
0.691 0.309 0.000
H35.1 Retinopathy of prematurity
0.691 0.309 0.000
M79.66 Pain in limb (Lower leg)
0.691 0.309 0.000
V40-V49 Car occupant injured in transport accident
0.690 0.310 0.000
F80-F89 Disorders of psychological development
0.690 0.310 0.000
Y95 Nosocomial condition
0.690 0.310 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.690 0.310 0.000
M15 Polyarthrosis
0.689 0.310 0.000
E13 Other specified diabetes mellitus
0.689 0.311 0.000
E12 Malnutrition-related diabetes mellitus
0.689 0.311 0.000
M11 Other crystal arthropathies
0.688 0.312 0.000
G25.3 Myoclonus
0.687 0.313 0.000
T90 Sequelae of injuries of head
0.686 0.314 0.000
E16 Other disorders of pancreatic internal secretion
0.684 0.315 0.000
D05.1 Intraductal carcinoma in situ
0.684 0.316 0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.684 0.316 0.000
C07 Malignant neoplasm of parotid gland
0.684 0.316 0.000
M79.00 Rheumatism, unspecified (Multiple sites)
0.683 0.316 0.000
E28 Ovarian dysfunction
0.683 0.317 0.000
M51.9 Intervertebral disk disorder, unspecified
0.683 0.317 0.000
I60-I69 Cerebrovascular diseases
0.683 0.317 0.000
I70 Atherosclerosis
0.683 0.317 0.000
H33.4 Traction detachment of retina
0.683 0.317 0.000
H33.1 Retinoschisis and retinal cysts
0.683 0.317 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.682 0.318 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.682 0.318 0.000
S40 Superficial injury of shoulder and upper arm
0.682 0.318 0.000
A80-A89 Viral infections of the central nervous system
0.682 0.318 0.000
H33.5 Other retinal detachments
0.681 0.319 0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.680 0.320 0.000
A09.9 Gastroenteritis and colitis of unspecified origin
0.679 0.321 0.000
G70 Myasthenia gravis and other myoneural disorders
0.678 0.321 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.678 0.322 0.000
G95 Other diseases of spinal cord
0.677 0.323 0.000
C25 Malignant neoplasm of pancreas
0.677 0.323 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.677 0.323 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.676 0.324 0.000
E11.9 Without complications
0.676 0.324 0.000
M19.8 Other specified arthrosis
0.675 0.325 0.000
M19.2 Other secondary arthrosis
0.675 0.325 0.000
E87.2 Acidosis
0.675 0.325 0.000
R78 Findings of drugs and other substances, not normally found in blood
0.675 0.325 0.000
R77 Other abnormalities of plasma proteins
0.675 0.325 0.000
R70 Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity
0.675 0.325 0.000
R75 Laboratory evidence of human immunodeficiency virus [HIV]
0.675 0.325 0.000
R71 Abnormality of red blood cells
0.675 0.325 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.675 0.325 0.000
Z01.7 Laboratory examination
0.674 0.326 0.000
G57.6 Lesion of plantar nerve
0.674 0.326 0.000
Z13.0 Special screening examination for diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.674 0.326 0.000
I74 Arterial embolism and thrombosis
0.673 0.327 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.673 0.327 0.000
Z72.9 Problem related to lifestyle, unspecified
0.673 0.327 0.000
Z72.8 Other problems related to lifestyle
0.673 0.327 0.000
Z72.6 Gambling and betting
0.673 0.327 0.000
Z72.5 High-risk sexual behaviour
0.673 0.327 0.000
Z72.4 Inappropriate diet and eating habits
0.673 0.327 0.000
Z72.3 Lack of physical exercise
0.673 0.327 0.000
Z72.2 Drug use
0.673 0.327 0.000
D02 Carcinoma in situ of middle ear and respiratory system
0.673 0.327 0.000
D01 Carcinoma in situ of other and unspecified digestive organs
0.673 0.327 0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.673 0.327 0.000
Z74 Problems related to care-provider dependency
0.672 0.328 0.000
G50 Disorders of trigeminal nerve
0.672 0.328 0.000
S80 Superficial injury of lower leg
0.671 0.328 0.000
S62 Fracture at wrist and hand level
0.671 0.329 0.000
M46.9 Inflammatory spondylopathy, unspecified
0.671 0.329 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.670 0.330 0.000
I78 Diseases of capillaries
0.670 0.330 0.000
M19.99 Arthrosis, unspecified (Site unspecified)
0.670 0.330 0.000
I50 Heart failure
0.669 0.331 0.000
C62 Malignant neoplasm of testis
0.668 0.331 0.000
M77 Other enthesopathies
0.668 0.332 0.000
M40-M43 Deforming dorsopathies
0.668 0.332 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.667 0.333 0.000
M47.87 Other spondylosis (Lumbosacral region)
0.666 0.333 0.000
E87.0 Hyperosmolality and hypernatraemia
0.665 0.335 0.000
Z10 Routine general health check-up of defined subpopulation
0.665 0.335 0.000
E11.3 With ophthalmic complications
0.664 0.336 0.000
H58 Other disorders of eye and adnexa in diseases classified elsewhere
0.664 0.336 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.664 0.336 0.000
R74 Abnormal serum enzyme levels
0.664 0.336 0.000
M19.95 Arthrosis, unspecified (Pelvic region and thigh)
0.663 0.336 0.000
I71.0 Dissection of aorta [any part]
0.663 0.337 0.000
M10 Gout
0.663 0.337 0.000
Z75.1 Person awaiting admission to adequate facility elsewhere
0.662 0.338 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.662 0.338 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.662 0.338 0.000
H36 Retinal disorders in diseases classified elsewhere
0.662 0.338 0.000
S64 Injury of nerves at wrist and hand level
0.662 0.338 0.000
H13 Disorders of conjunctiva in diseases classified elsewhere
0.661 0.339 0.000
M47.98 Spondylosis, unspecified (Sacral and sacrococcygeal region)
0.661 0.339 0.000
M47.97 Spondylosis, unspecified (Lumbosacral region)
0.661 0.339 0.000
M47.95 Spondylosis, unspecified (Thoracolumbar region)
0.661 0.339 0.000
M47.94 Spondylosis, unspecified (Thoracic region)
0.661 0.339 0.000
M47.93 Spondylosis, unspecified (Cervicothoracic region)
0.661 0.339 0.000
M47.91 Spondylosis, unspecified (Occipito-atlanto-axial region)
0.661 0.339 0.000
D03.6 Melanoma in situ of upper limb, including shoulder
0.661 0.339 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.660 0.340 0.000
M81.9 Osteoporosis, unspecified
0.660 0.340 0.000
M94 Other disorders of cartilage
0.659 0.341 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.659 0.341 0.000
R73 Elevated blood glucose level
0.658 0.342 0.000
B95-B98 Bacterial, viral and other infectious agents
0.658 0.342 0.000
M51.8 Other specified intervertebral disk disorders
0.657 0.343 0.000
E53 Deficiency of other B group vitamins
0.657 0.343 0.000
R85 Abnormal findings in specimens from digestive organs and abdominal cavity
0.657 0.343 0.000
I24 Other acute ischaemic heart diseases
0.657 0.343 0.000
D09 Carcinoma in situ of other and unspecified sites
0.656 0.344 0.000
M79.9 Soft tissue disorder, unspecified
0.656 0.344 0.000
M79.5 Residual foreign body in soft tissue
0.656 0.344 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.656 0.344 0.000
M79.3 Panniculitis, unspecified
0.656 0.344 0.000
M79.2 Neuralgia and neuritis, unspecified
0.656 0.344 0.000
M79.1 Myalgia
0.656 0.344 0.000
F99-F99 Unspecified mental disorder
0.656 0.344 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.656 0.344 0.000
C79.6 Secondary malignant neoplasm of ovary
0.656 0.344 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.656 0.344 0.000
C79.2 Secondary malignant neoplasm of skin
0.656 0.344 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.656 0.344 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.656 0.344 0.000
E10.3 With ophthalmic complications
0.655 0.345 0.000
I72 Other aneurysm
0.654 0.346 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.654 0.346 0.000
B99-B99 Other infectious diseases
0.653 0.347 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.653 0.347 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.653 0.347 0.000
B65-B83 Helminthiases
0.653 0.347 0.000
B50-B64 Protozoal diseases
0.653 0.347 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.653 0.347 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.653 0.347 0.000
A75-A79 Rickettsioses
0.653 0.347 0.000
A70-A74 Other diseases caused by chlamydiae
0.653 0.347 0.000
A65-A69 Other spirochaetal diseases
0.653 0.347 0.000
A20-A28 Certain zoonotic bacterial diseases
0.653 0.347 0.000
A15-A19 Tuberculosis
0.653 0.347 0.000
G54 Nerve root and plexus disorders
0.653 0.347 0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease
0.652 0.348 0.000
R26.3 Immobility
0.652 0.348 0.000
I15 Secondary hypertension
0.652 0.348 0.000
I13 Hypertensive heart and renal disease
0.652 0.348 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.652 0.348 0.000
E83.3 Disorders of phosphorus metabolism
0.652 0.348 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.652 0.348 0.000
F70-F79 Mental retardation
0.652 0.348 0.000
E87.7 Fluid overload
0.652 0.348 0.000
M50.2 Other cervical disk displacement
0.652 0.348 0.000
E11.8 With unspecified complications
0.651 0.349 0.000
E11.7 With multiple complications
0.651 0.349 0.000
E11.6 With other specified complications
0.651 0.349 0.000
E11.1 With ketoacidosis
0.651 0.349 0.000
E11.0 With coma
0.651 0.349 0.000
R76 Other abnormal immunological findings in serum
0.650 0.350 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.650 0.350 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.650 0.350 0.000
Z29 Need for other prophylactic measures
0.649 0.350 0.000
H49 Paralytic strabismus
0.649 0.351 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.649 0.351 0.000
S50-S59 Injuries to the elbow and forearm
0.649 0.351 0.000
F60-F69 Disorders of adult personality and behaviour
0.649 0.351 0.000
M53.38 Sacrococcygeal disorders, not elsewhere classified-Sacral/s
0.648 0.352 0.000
S89.9 Unspecified injury of lower leg
0.647 0.353 0.000
G58.8 Other specified mononeuropathies
0.646 0.354 0.000
Z09.7 Follow-up examination after combined treatment for other conditions
0.646 0.354 0.000
Z09.4 Follow-up examination after treatment of fracture
0.646 0.354 0.000
Z09.3 Follow-up examination after psychotherapy
0.646 0.354 0.000
Z09.1 Follow-up examination after radiotherapy for other conditions
0.646 0.354 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.646 0.354 0.000
M07.3 Other psoriatic arthropathies
0.645 0.354 0.000
M79.79 Fibromyalgia (Site unspecified)
0.645 0.355 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.645 0.355 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.645 0.355 0.000
M25 Other joint disorders, not elsewhere classified
0.645 0.355 0.000
G71 Primary disorders of muscles
0.645 0.355 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.645 0.355 0.000
M54.99 Dorsalgia, unspecified (Site unspecified)
0.644 0.355 0.000
F23 Acute and transient psychotic disorders
0.644 0.356 0.000
F22 Persistent delusional disorders
0.644 0.356 0.000
D04.7 Skin of lower limb, including hip
0.644 0.356 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.643 0.357 0.000
M70.2 Olecranon bursitis
0.643 0.357 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.643 0.357 0.000
S08 Traumatic amputation of part of head
0.643 0.357 0.000
S07 Crushing injury of head
0.643 0.357 0.000
S05 Injury of eye and orbit
0.643 0.357 0.000
S04 Injury of cranial nerves
0.643 0.357 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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