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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs116903209
log Bayes Factor = 21.5852
Chromosome 13   position 38,538,467  (GRCh37) Explore rs116903209 on Ensembl!
Variant rs116903209 is part of Cluster X0047

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter XIV Diseases of the genitourinary system
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
M15-M19 Arthrosis
0.999 0.001 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.999 0.001 0.000
I60-I69 Cerebrovascular diseases
0.998 0.002 0.000
M50-M54 Other dorsopathies
0.996 0.004 0.000
M19 Other arthrosis
0.995 0.005 0.000
Z92 Personal history of medical treatment
0.993 0.007 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.993 0.007 0.000
M19.9 Arthrosis, unspecified
0.992 0.008 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.992 0.008 0.000
M20-M25 Other joint disorders
0.991 0.009 0.000
R50-R69 General symptoms and signs
0.990 0.010 0.000
M54 Dorsalgia
0.989 0.011 0.000
N17-N19 Renal failure
0.989 0.011 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.988 0.012 0.000
Z72 Problems related to lifestyle
0.979 0.021 0.000
M25 Other joint disorders, not elsewhere classified
0.978 0.022 0.000
Chapter XI Diseases of the digestive system
0.977 0.023 0.000
I10-I15 Hypertensive diseases
0.976 0.024 0.000
N30-N39 Other diseases of urinary system
0.974 0.026 0.000
N85 Other noninflammatory disorders of uterus, except cervix
0.968 0.032 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.967 0.033 0.000
Chapter II Neoplasms
0.966 0.034 0.000
M54.5 Low back pain
0.966 0.034 0.000
I67 Other cerebrovascular diseases
0.965 0.035 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.964 0.036 0.000
Z92.1 Personal history of long-term (current) use of anticoagulants
0.963 0.037 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.962 0.038 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.961 0.039 0.000
R55 Syncope and collapse
0.959 0.041 0.000
R63 Symptoms and signs concerning food and fluid intake
0.959 0.041 0.000
Z92.4 Personal history of major surgery, not elsewhere classified
0.958 0.042 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.958 0.042 0.000
I12 Hypertensive renal disease
0.957 0.043 0.000
I69 Sequelae of cerebrovascular disease
0.949 0.051 0.000
N18 Chronic renal failure
0.949 0.051 0.000
Chapter XX External causes of morbidity and mortality
0.947 0.053 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.945 0.055 0.000
R53 Malaise and fatigue
0.945 0.055 0.000
Z72.1 Alcohol use
0.944 0.056 0.000
M05-M14 Inflammatory polyarthropathies
0.941 0.059 0.000
N17 Acute renal failure
0.941 0.059 0.000
N30 Cystitis
0.940 0.060 0.000
N80 Endometriosis
0.939 0.061 0.000
I12.0 Hypertensive renal disease with renal failure
0.937 0.063 0.000
M19.99 Arthrosis, unspecified (Site unspecified)
0.935 0.065 0.000
K40-K46 Hernia
0.933 0.067 0.000
M19.97 Arthrosis, unspecified (Ankle and foot)
0.932 0.068 0.000
K70-K77 Diseases of liver
0.927 0.073 0.000
N85.0 Endometrial glandular hyperplasia
0.926 0.074 0.000
Z88.1 Personal history of allergy to other antibiotic agents
0.924 0.076 0.000
I95 Hypotension
0.923 0.077 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.920 0.080 0.000
R63.4 Abnormal weight loss
0.916 0.084 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.914 0.086 0.000
Chapter VII Diseases of the eye and adnexa
0.912 0.088 0.000
M54.56 Low back pain (Lumbar region)
0.912 0.088 0.000
I20-I25 Ischaemic heart diseases
0.911 0.089 0.000
Z96 Presence of other functional implants
0.911 0.089 0.000
N25-N29 Other disorders of kidney and ureter
0.909 0.091 0.000
S60-S69 Injuries to the wrist and hand
0.908 0.092 0.000
N17.9 Acute renal failure, unspecified
0.907 0.093 0.000
Z92.3 Personal history of irradiation
0.907 0.093 0.000
I73 Other peripheral vascular diseases
0.907 0.093 0.000
Z90.5 Acquired absence of kidney
0.907 0.093 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.906 0.094 0.000
M19.96 Arthrosis, unspecified-Lower leg
0.903 0.097 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.903 0.097 0.000
K43 Ventral hernia
0.900 0.100 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.900 0.100 0.000
M54.9 Dorsalgia, unspecified
0.899 0.101 0.000
K90-K93 Other diseases of the digestive system
0.899 0.101 0.000
Z72.0 Tobacco use
0.898 0.102 0.000
M54.59 Low back pain (Site unspecified)
0.897 0.103 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.896 0.104 0.000
N30.9 Cystitis, unspecified
0.894 0.106 0.000
M19.90 Arthrosis, unspecified (Multiple sites)
0.892 0.108 0.000
I95.9 Hypotension, unspecified
0.891 0.109 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.891 0.109 0.000
C51-C58 Malignant neoplasms of female genital organs
0.886 0.114 0.000
D10-D36 Benign neoplasms
0.883 0.117 0.000
I25 Chronic ischaemic heart disease
0.882 0.118 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.880 0.120 0.000
I74 Arterial embolism and thrombosis
0.879 0.121 0.000
K43.9 Ventral hernia without obstruction or gangrene
0.878 0.122 0.000
R52 Pain, not elsewhere classified
0.878 0.122 0.000
D25 Leiomyoma of uterus
0.877 0.123 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.877 0.123 0.000
M25.5 Pain in joint
0.875 0.125 0.000
Z88.5 Personal history of allergy to narcotic agent
0.874 0.126 0.000
Z90.1 Acquired absence of breast(s)
0.874 0.126 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.872 0.128 0.000
I63 Cerebral infarction
0.872 0.128 0.000
I67.1 Cerebral aneurysm, nonruptured
0.869 0.131 0.000
M18 Arthrosis of first carpometacarpal joint
0.869 0.131 0.000
Z96.6 Presence of orthopaedic joint implants
0.862 0.138 0.000
I67.9 Cerebrovascular disease, unspecified
0.862 0.138 0.000
Chapter X Diseases of the respiratory system
0.858 0.142 0.000
K92 Other diseases of digestive system
0.858 0.142 0.000
N81 Female genital prolapse
0.857 0.143 0.000
N89 Other noninflammatory disorders of vagina
0.857 0.143 0.000
M17 Gonarthrosis [arthrosis of knee]
0.856 0.144 0.000
N30.1 Interstitial cystitis (chronic)
0.854 0.146 0.000
M13 Other arthritis
0.852 0.148 0.000
N80.3 Endometriosis of pelvic peritoneum
0.851 0.149 0.000
M54.99 Dorsalgia, unspecified (Site unspecified)
0.849 0.150 0.000
Z75 Problems related to medical facilities and other health care
0.849 0.151 0.000
I60 Subarachnoid haemorrhage
0.847 0.153 0.000
N39 Other disorders of urinary system
0.845 0.155 0.000
I73.0 Raynaud's syndrome
0.845 0.155 0.000
M25.57 Pain in joint (Ankle and foot)
0.844 0.156 0.000
N18.9 Chronic renal failure, unspecified
0.843 0.157 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.843 0.157 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.842 0.158 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.842 0.158 0.000
M25.4 Effusion of joint
0.841 0.159 0.000
M24 Other specific joint derangements
0.841 0.159 0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified
0.839 0.161 0.000
M25.3 Other instability of joint
0.839 0.161 0.000
N88 Other noninflammatory disorders of cervix uteri
0.837 0.163 0.000
M51 Other intervertebral disk disorders
0.837 0.163 0.000
K75 Other inflammatory liver diseases
0.836 0.164 0.000
Z73 Problems related to life-management difficulty
0.834 0.166 0.000
N90 Other noninflammatory disorders of vulva and perineum
0.829 0.171 0.000
D25.1 Intramural leiomyoma of uterus
0.828 0.172 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.826 0.174 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.824 0.176 0.000
M22 Disorders of patella
0.823 0.177 0.000
M45-M49 Spondylopathies
0.823 0.177 0.000
S80-S89 Injuries to the knee and lower leg
0.821 0.179 0.000
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
0.820 0.180 0.000
O48 Prolonged pregnancy
0.818 0.182 0.000
N28 Other disorders of kidney and ureter, not elsewhere classified
0.817 0.183 0.000
I61 Intracerebral haemorrhage
0.816 0.184 0.000
N18.4 Chronic kidney disease, stage 4
0.815 0.185 0.000
R59 Enlarged lymph nodes
0.813 0.187 0.000
J40-J47 Chronic lower respiratory diseases
0.810 0.190 0.000
M17.0 Primary gonarthrosis, bilateral
0.809 0.191 0.000
Z89 Acquired absence of limb
0.808 0.192 0.000
M54.1 Radiculopathy
0.805 0.195 0.000
Chapter VI Diseases of the nervous system
0.805 0.195 0.000
Z90.7 Acquired absence of genital organ(s)
0.801 0.199 0.000
R52.2 Other chronic pain
0.800 0.200 0.000
K92.2 Gastro-intestinal haemorrhage, unspecified
0.799 0.201 0.000
S61 Open wound of wrist and hand
0.797 0.203 0.000
N39.3 Stress incontinence
0.797 0.203 0.000
N85.2 Hypertrophy of uterus
0.795 0.205 0.000
N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.795 0.205 0.000
N80.0 Endometriosis of uterus
0.794 0.206 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.793 0.207 0.000
K76 Other diseases of liver
0.793 0.207 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.792 0.208 0.000
W00-W19 Falls
0.792 0.208 0.000
M16 Coxarthrosis [arthrosis of hip]
0.789 0.211 0.000
O42 Premature rupture of membranes
0.789 0.211 0.000
K42 Umbilical hernia
0.788 0.212 0.000
O60-O75 Complications of labour and delivery
0.786 0.214 0.000
M25.0 Haemarthrosis
0.786 0.214 0.000
K86 Other diseases of pancreas
0.784 0.216 0.000
C53 Malignant neoplasm of cervix uteri
0.783 0.217 0.000
N85.8 Other specified noninflammatory disorders of uterus
0.783 0.217 0.000
S20-S29 Injuries to the thorax
0.783 0.217 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.782 0.218 0.000
I62 Other nontraumatic intracranial haemorrhage
0.782 0.218 0.000
Z84 Family history of other conditions
0.782 0.218 0.000
M21 Other acquired deformities of limbs
0.782 0.218 0.000
N81.4 Uterovaginal prolapse, unspecified
0.782 0.218 0.000
R63.1 Polydipsia
0.781 0.219 0.000
N18.3 Chronic kidney disease, stage 3
0.780 0.220 0.000
M91-M94 Chondropathies
0.779 0.221 0.000
D25.9 Leiomyoma of uterus, unspecified
0.779 0.221 0.000
M50 Cervical disk disorders
0.779 0.221 0.000
M25.9 Joint disorder, unspecified
0.778 0.221 0.000
N87 Dysplasia of cervix uteri
0.778 0.222 0.000
R93.5 Abnormal findings on diagnostic imaging of other abdominal regions, including retroperitoneum
0.778 0.222 0.000
D25.2 Subserosal leiomyoma of uterus
0.777 0.223 0.000
D24 Benign neoplasm of breast
0.775 0.225 0.000
Z29 Need for other prophylactic measures
0.773 0.227 0.000
X60-X84 Intentional self-harm
0.773 0.227 0.000
S90-S99 Injuries to the ankle and foot
0.772 0.228 0.000
Z60 Problems related to social environment
0.771 0.229 0.000
M35 Other systemic involvement of connective tissue
0.771 0.229 0.000
M10 Gout
0.770 0.230 0.000
J47 Bronchiectasis
0.769 0.231 0.000
N85.4 Malposition of uterus
0.769 0.231 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.767 0.233 0.000
Z99.1 Dependence on respirator
0.767 0.233 0.000
M25.7 Osteophyte
0.767 0.233 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.767 0.233 0.000
Z88.4 Personal history of allergy to anaesthetic agent
0.766 0.234 0.000
I12.9 Hypertensive renal disease without renal failure
0.765 0.235 0.000
C64-C68 Malignant neoplasms of urinary tract
0.765 0.235 0.000
W20-W49 Exposure to inanimate mechanical forces
0.765 0.235 0.000
N10-N16 Renal tubulo-interstitial diseases
0.764 0.236 0.000
Z88.3 Personal history of allergy to other anti-infective agents
0.764 0.236 0.000
O00-O08 Pregnancy with abortive outcome
0.764 0.236 0.000
Z94 Transplanted organ and tissue status
0.762 0.238 0.000
N30.0 Acute cystitis
0.762 0.238 0.000
Z99.3 Dependence on wheelchair
0.761 0.239 0.000
I67.8 Other specified cerebrovascular diseases
0.760 0.240 0.000
M13.9 Arthritis, unspecified
0.759 0.241 0.000
H40-H42 Glaucoma
0.759 0.241 0.000
Z96.0 Presence of urogenital implants
0.759 0.241 0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.758 0.242 0.000
M06 Other rheumatoid arthritis
0.758 0.242 0.000
I77 Other disorders of arteries and arterioles
0.755 0.245 0.000
M65-M68 Disorders of synovium and tendon
0.755 0.245 0.000
K35-K38 Diseases of appendix
0.753 0.247 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.753 0.247 0.000
K85 Acute pancreatitis
0.753 0.247 0.000
Z88.8 Personal history of allergy to other drugs, medicaments and biological substances
0.752 0.248 0.000
R47-R49 Symptoms and signs involving speech and voice
0.751 0.249 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.750 0.250 0.000
I69.3 Sequelae of cerebral infarction
0.747 0.253 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.747 0.253 0.000
N20-N23 Urolithiasis
0.746 0.254 0.000
Z75.1 Person awaiting admission to adequate facility elsewhere
0.746 0.254 0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.746 0.254 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.745 0.255 0.000
I25.2 Old myocardial infarction
0.744 0.256 0.000
M25.46 Effusion of joint (Lower leg)
0.743 0.257 0.000
Z22 Carrier of infectious disease
0.742 0.258 0.000
T66-T78 Other and unspecified effects of external causes
0.742 0.258 0.000
M19.95 Arthrosis, unspecified (Pelvic region and thigh)
0.741 0.259 0.000
R63.0 Anorexia
0.740 0.259 0.000
Z95.2 Presence of prosthetic heart valve
0.740 0.260 0.000
M25.36 Other instability of joint (Lower leg)
0.739 0.261 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.739 0.261 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.739 0.261 0.000
Chapter XXII Codes for special purposes
0.738 0.261 0.000
Z90.3 Acquired absence of part of stomach
0.737 0.263 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.737 0.263 0.000
I73.9 Peripheral vascular disease, unspecified
0.737 0.263 0.000
D25.0 Submucous leiomyoma of uterus
0.737 0.263 0.000
M54.4 Lumbago with sciatica
0.736 0.264 0.000
Chapter I Certain infectious and parasitic diseases
0.736 0.264 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.735 0.265 0.000
N28.1 Cyst of kidney, acquired
0.734 0.266 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.733 0.266 0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified
0.733 0.267 0.000
I10 Essential (primary) hypertension
0.733 0.267 0.000
V40-V49 Car occupant injured in transport accident
0.732 0.268 0.000
N80.9 Endometriosis, unspecified
0.731 0.269 0.000
N31.9 Neuromuscular dysfunction of bladder, unspecified
0.730 0.270 0.000
R59.9 Enlarged lymph nodes, unspecified
0.729 0.271 0.000
N26 Unspecified contracted kidney
0.729 0.271 0.000
I67.2 Cerebral atherosclerosis
0.729 0.271 0.000
C56 Malignant neoplasm of ovary
0.729 0.271 0.000
I63.8 Other cerebral infarction
0.729 0.271 0.000
S82 Fracture of lower leg, including ankle
0.728 0.272 0.000
D16 Benign neoplasm of bone and articular cartilage
0.727 0.273 0.000
Z73.9 Problem related to life-management difficulty, unspecified
0.726 0.274 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.726 0.274 0.000
D48.5 Skin
0.725 0.275 0.000
H30-H36 Disorders of choroid and retina
0.725 0.275 0.000
M54.3 Sciatica
0.725 0.275 0.000
Z96.7 Presence of other bone and tendon implants
0.724 0.276 0.000
S68 Traumatic amputation of wrist and hand
0.723 0.277 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.723 0.277 0.000
M17.3 Other posttraumatic gonarthrosis
0.722 0.278 0.000
M24.1 Other articular cartilage disorders
0.721 0.279 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.721 0.279 0.000
J43 Emphysema
0.721 0.279 0.000
N18.2 Chronic kidney disease, stage 2
0.721 0.279 0.000
M86-M90 Other osteopathies
0.720 0.280 0.000
I95.1 Orthostatic hypotension
0.720 0.280 0.000
N90.4 Leukoplakia of vulva
0.719 0.281 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I99 Other and unspecified disorders of circulatory system
0.717 0.283 0.000
J00-J06 Acute upper respiratory infections
0.717 0.283 0.000
M15 Polyarthrosis
0.716 0.284 0.000
S67 Crushing injury of wrist and hand
0.716 0.284 0.000
Z81 Family history of mental and behavioural disorders
0.716 0.284 0.000
K44 Diaphragmatic hernia
0.716 0.284 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.715 0.284 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.715 0.284 0.000
N89.9 Noninflammatory disorder of vagina, unspecified
0.715 0.285 0.000
N81.2 Incomplete uterovaginal prolapse
0.715 0.285 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.715 0.285 0.000
Z57 Occupational exposure to risk-factors
0.714 0.286 0.000
V10-V19 Pedal cyclist injured in transport accident
0.714 0.286 0.000
M53 Other dorsopathies, not elsewhere classified
0.714 0.286 0.000
M19.8 Other specified arthrosis
0.713 0.287 0.000
M19.2 Other secondary arthrosis
0.713 0.287 0.000
M19.1 Posttraumatic arthrosis of other joints
0.713 0.287 0.000
I22 Subsequent myocardial infarction
0.712 0.288 0.000
Z92.9 Personal history of medical treatment, unspecified
0.712 0.288 0.000
Z92.8 Personal history of other medical treatment
0.712 0.288 0.000
Z92.5 Personal history of rehabilitation measures
0.712 0.288 0.000
Z92.0 Personal history of contraception
0.712 0.288 0.000
Z76 Persons encountering health services in other circumstances
0.712 0.288 0.000
Z70 Counselling related to sexual attitude, behaviour and orientation
0.712 0.288 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.712 0.288 0.000
M19.98 Arthrosis, unspecified (Other)
0.711 0.289 0.000
M19.92 Arthrosis, unspecified (Upper arm)
0.711 0.289 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.711 0.289 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.710 0.289 0.000
M34 Systemic sclerosis
0.710 0.289 0.000
M33 Dermatopolymyositis
0.710 0.289 0.000
M32 Systemic lupus erythematosus
0.710 0.289 0.000
M30 Polyarteritis nodosa and related conditions
0.710 0.289 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.710 0.289 0.000
Q50-Q56 Congenital malformations of genital organs
0.710 0.289 0.000
R68 Other general symptoms and signs
0.710 0.290 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.710 0.290 0.000
R62 Lack of expected normal physiological development
0.710 0.290 0.000
R57 Shock, not elsewhere classified
0.710 0.290 0.000
R64 Cachexia
0.710 0.290 0.000
R58 Haemorrhage, not elsewhere classified
0.710 0.290 0.000
H43-H45 Disorders of vitreous body and globe
0.710 0.290 0.000
C53.9 Cervix uteri, unspecified
0.710 0.290 0.000
M54.8 Other dorsalgia
0.709 0.291 0.000
M54.6 Pain in thoracic spine
0.709 0.291 0.000
M54.0 Panniculitis affecting regions of neck and back
0.709 0.291 0.000
N39.4 Other specified urinary incontinence
0.709 0.291 0.000
N98 Complications associated with artificial fertilisation
0.709 0.291 0.000
N91 Absent, scanty and rare menstruation
0.709 0.291 0.000
N82 Fistulae involving female genital tract
0.709 0.291 0.000
N96 Habitual aborter
0.709 0.291 0.000
S62 Fracture at wrist and hand level
0.708 0.292 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.708 0.292 0.000
M31 Other necrotising vasculopathies
0.707 0.293 0.000
R29.6 Tendency to fall, not elsewhere classified
0.707 0.293 0.000
N99-N99 Other disorders of the genitourinary system
0.706 0.293 0.000
S40-S49 Injuries to the shoulder and upper arm
0.706 0.293 0.000
K76.0 Fatty (change of) liver, not elsewhere classified
0.706 0.293 0.000
R93.4 Abnormal findings on diagnostic imaging of urinary organs
0.705 0.295 0.000
K86.0 Alcohol-induced chronic pancreatitis
0.705 0.295 0.000
S61.0 Open wound of finger(s) without damage to nail
0.704 0.296 0.000
N18.5 Chronic kidney disease, stage 5
0.704 0.296 0.000
K75.8 Other specified inflammatory liver diseases
0.702 0.298 0.000
N40-N51 Diseases of male genital organs
0.702 0.298 0.000
Z72.9 Problem related to lifestyle, unspecified
0.702 0.298 0.000
Z72.8 Other problems related to lifestyle
0.702 0.298 0.000
Z72.6 Gambling and betting
0.702 0.298 0.000
Z72.5 High-risk sexual behaviour
0.702 0.298 0.000
Z72.4 Inappropriate diet and eating habits
0.702 0.298 0.000
Z72.3 Lack of physical exercise
0.702 0.298 0.000
Z72.2 Drug use
0.702 0.298 0.000
O44 Placenta praevia
0.702 0.298 0.000
D00-D09 In situ neoplasms
0.701 0.299 0.000
Chapter VIII Diseases of the ear and mastoid process
0.701 0.299 0.000
H00 Hordeolum and chalazion
0.701 0.299 0.000
K75.9 Inflammatory liver disease, unspecified
0.701 0.299 0.000
M25.8 Other specified joint disorders
0.701 0.299 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.701 0.299 0.000
M25.2 Flail joint
0.701 0.299 0.000
M25.1 Fistula of joint
0.701 0.299 0.000
N31.2 Flaccid neuropathic bladder, not elsewhere classified
0.701 0.299 0.000
Z88.7 Personal history of allergy to serum and vaccine
0.700 0.300 0.000
I15 Secondary hypertension
0.700 0.300 0.000
I13 Hypertensive heart and renal disease
0.700 0.300 0.000
I11 Hypertensive heart disease
0.700 0.300 0.000
M18.1 Other primary arthrosis of first carpometacarpal joint
0.699 0.301 0.000
R51 Headache
0.699 0.301 0.000
I74.5 Embolism and thrombosis of iliac artery
0.699 0.301 0.000
Z90.6 Acquired absence of other parts of urinary tract
0.698 0.302 0.000
N37 Urethral disorders in diseases classified elsewhere
0.698 0.302 0.000
N34 Urethritis and urethral syndrome
0.698 0.302 0.000
N33 Bladder disorders in diseases classified elsewhere
0.698 0.302 0.000
N97 Female infertility
0.698 0.302 0.000
K74 Fibrosis and cirrhosis of liver
0.698 0.302 0.000
Z88.6 Personal history of allergy to analgesic agent
0.697 0.303 0.000
I72 Other aneurysm
0.696 0.304 0.000
Y86 Sequelae of other accidents
0.696 0.304 0.000
K70 Alcoholic liver disease
0.696 0.304 0.000
D45 Polycythaemia vera
0.695 0.305 0.000
N85.7 Haematometra
0.694 0.306 0.000
N85.6 Intra-uterine synechiae
0.694 0.306 0.000
N85.5 Inversion of uterus
0.694 0.306 0.000
N85.3 Subinvolution of uterus
0.694 0.306 0.000
N85.1 Endometrial adenomatous hyperplasia
0.694 0.306 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.694 0.306 0.000
Z88.9 Personal history of allergy to unspecified drugs, medicaments and biological substances
0.693 0.306 0.000
M22.2 Patellofemoral disorders
0.693 0.307 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.693 0.307 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.693 0.307 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.693 0.307 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.693 0.307 0.000
M54.55 Low back pain (Thoracolumbar region)
0.692 0.308 0.000
M54.54 Low back pain-Thoracic
0.692 0.308 0.000
M54.53 Low back pain-Cervicothoracic
0.692 0.308 0.000
M54.52 Low back pain-Cervical
0.692 0.308 0.000
M54.51 Low back pain-Occipit-atl-axl
0.692 0.308 0.000
M54.50 Low back pain (Multiple sites in spine)
0.692 0.308 0.000
I67.7 Cerebral arteritis, not elsewhere classified
0.692 0.308 0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.692 0.308 0.000
I67.5 Moyamoya disease
0.692 0.308 0.000
I67.4 Hypertensive encephalopathy
0.692 0.308 0.000
I67.3 Progressive vascular leukoencephalopathy
0.692 0.308 0.000
I67.0 Dissection of cerebral arteries, nonruptured
0.692 0.308 0.000
R26 Abnormalities of gait and mobility
0.692 0.308 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.692 0.308 0.000
O43 Placental disorders
0.691 0.309 0.000
K92.1 Melaena
0.691 0.309 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.691 0.309 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.690 0.309 0.000
O47 False labour
0.690 0.310 0.000
K85.9 Acute pancreatitis, unspecified
0.690 0.310 0.000
T33-T35 Frostbite
0.690 0.310 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.690 0.310 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.690 0.310 0.000
T00-T07 Injuries involving multiple body regions
0.690 0.310 0.000
S10-S19 Injuries to the neck
0.690 0.310 0.000
H10-H13 Disorders of conjunctiva
0.690 0.310 0.000
Z90.0 Acquired absence of part of head and neck
0.689 0.311 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.688 0.311 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.688 0.312 0.000
M40-M43 Deforming dorsopathies
0.688 0.312 0.000
M80-M85 Disorders of bone density and structure
0.688 0.312 0.000
Z98 Other postsurgical states
0.687 0.312 0.000
M51.8 Other specified intervertebral disk disorders
0.687 0.313 0.000
R63.6 Insufficient intake of food and water due to self neglect
0.687 0.313 0.000
R63.5 Abnormal weight gain
0.687 0.313 0.000
R63.3 Feeding difficulties and mismanagement
0.687 0.313 0.000
R63.2 Polyphagia
0.687 0.313 0.000
R63.8 Other symptoms and signs concerning food and fluid intake
0.687 0.313 0.000
M19.0 Primary arthrosis of other joints
0.687 0.313 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.687 0.313 0.000
I61.9 Intracerebral haemorrhage, unspecified
0.686 0.314 0.000
Z97 Presence of other devices
0.686 0.314 0.000
N00-N08 Glomerular diseases
0.686 0.314 0.000
N88.9 Noninflammatory disorder of cervix uteri, unspecified
0.686 0.314 0.000
N80.1 Endometriosis of ovary
0.686 0.314 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.686 0.314 0.000
N81.5 Vaginal enterocele
0.686 0.314 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.685 0.315 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.685 0.315 0.000
M13.0 Polyarthritis, unspecified
0.685 0.315 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.685 0.315 0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.685 0.315 0.000
Z60.2 Living alone
0.685 0.315 0.000
D48.1 Connective and other soft tissue
0.684 0.316 0.000
S70-S79 Injuries to the hip and thigh
0.683 0.317 0.000
M54.2 Cervicalgia
0.682 0.318 0.000
Z74 Problems related to care-provider dependency
0.682 0.318 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.682 0.318 0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.680 0.319 0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.680 0.319 0.000
I69.1 Sequelae of intracerebral haemorrhage
0.680 0.319 0.000
I69.0 Sequelae of subarachnoid haemorrhage
0.680 0.319 0.000
M13.99 Arthritis, unspecified (Site unspecified)
0.680 0.320 0.000
N18.8 Other chronic renal failure
0.680 0.320 0.000
N18.1 Chronic kidney disease, stage 1
0.680 0.320 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.680 0.320 0.000
N28.8 Other specified disorders of kidney and ureter
0.680 0.320 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.680 0.320 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.679 0.321 0.000
Y35-Y36 Legal intervention and operations of war
0.679 0.321 0.000
Y10-Y34 Event of undetermined intent
0.679 0.321 0.000
Y00-Y09 Assault
0.679 0.321 0.000
X85-X99 Assault
0.679 0.321 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.679 0.321 0.000
X50-X57 Overexertion, travel and privation
0.679 0.321 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.679 0.321 0.000
X30-X39 Exposure to forces of nature
0.679 0.321 0.000
X20-X29 Contact with venomous animals and plants
0.679 0.321 0.000
X10-X19 Contact with heat and hot substances
0.679 0.321 0.000
X00-X09 Exposure to smoke, fire and flames
0.679 0.321 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.679 0.321 0.000
W75-W84 Other accidental threats to breathing
0.679 0.321 0.000
W65-W74 Accidental drowning and submersion
0.679 0.321 0.000
W50-W64 Exposure to animate mechanical forces
0.679 0.321 0.000
V98-V99 Other and unspecified transport accidents
0.679 0.321 0.000
V95-V97 Air and space transport accidents
0.679 0.321 0.000
V90-V94 Water transport accidents
0.679 0.321 0.000
V80-V89 Other land transport accidents
0.679 0.321 0.000
V70-V79 Bus occupant injured in transport accident
0.679 0.321 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.679 0.321 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.679 0.321 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.679 0.321 0.000
V20-V29 Motorcycle rider injured in transport accident
0.679 0.321 0.000
V01-V09 Pedestrian injured in transport accident
0.679 0.321 0.000
D34 Benign neoplasm of thyroid gland
0.679 0.321 0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.679 0.321 0.000
M05 Seropositive rheumatoid arthritis
0.679 0.321 0.000
N20 Calculus of kidney and ureter
0.678 0.322 0.000
N81.8 Other female genital prolapse
0.678 0.322 0.000
O85-O92 Complications predominantly related to the puerperium
0.677 0.322 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.677 0.323 0.000
Z90.8 Acquired absence of other organs
0.676 0.324 0.000
M14 Arthropathies in other diseases classified elsewhere
0.675 0.325 0.000
M12 Other specific arthropathies
0.675 0.325 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.675 0.325 0.000
M08 Juvenile arthritis
0.675 0.325 0.000
N17.8 Other acute renal failure
0.675 0.325 0.000
N17.2 Acute renal failure with medullary necrosis
0.675 0.325 0.000
N17.1 Acute renal failure with acute cortical necrosis
0.675 0.325 0.000
N17.0 Acute renal failure with tubular necrosis
0.675 0.325 0.000
N30.4 Irradiation cystitis
0.674 0.326 0.000
N30.3 Trigonitis
0.674 0.326 0.000
M11 Other crystal arthropathies
0.673 0.326 0.000
N80.8 Other endometriosis
0.673 0.327 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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