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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs117040525
log Bayes Factor = 29.602
Chromosome 15   position 36,563,570  (GRCh37) Explore rs117040525 on Ensembl!
Variant rs117040525 is part of Cluster X0166

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Z86 Personal history of certain other diseases
0.999 0.001 0.000
D10-D36 Benign neoplasms
0.999 0.001 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.999 0.001 0.000
M15-M19 Arthrosis
0.999 0.001 0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal
0.998 0.002 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.998 0.002 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.997 0.003 0.000
Z86.4 Personal history of psychoactive substance abuse
0.996 0.004 0.000
Chapter I Certain infectious and parasitic diseases
0.995 0.005 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.994 0.006 0.000
E70-E90 Metabolic disorders
0.993 0.007 0.000
Chapter XX External causes of morbidity and mortality
0.991 0.009 0.000
C34 Malignant neoplasm of bronchus and lung
0.990 0.010 0.000
Chapter XIV Diseases of the genitourinary system
0.990 0.010 0.000
Chapter IX Diseases of the circulatory system
0.990 0.010 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.988 0.012 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.987 0.013 0.000
B95-B98 Bacterial, viral and other infectious agents
0.985 0.015 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.984 0.016 0.000
M16 Coxarthrosis [arthrosis of hip]
0.984 0.016 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.984 0.016 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.980 0.020 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.979 0.021 0.000
M16.1 Other primary coxarthrosis
0.977 0.023 0.000
I73 Other peripheral vascular diseases
0.977 0.023 0.000
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms
0.976 0.024 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.975 0.025 0.000
Z09.9 Follow-up examination after unspecified treatment for other conditions
0.973 0.027 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.970 0.030 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.970 0.030 0.000
C34.9 Bronchus or lung, unspecified
0.966 0.034 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.966 0.034 0.000
R30-R39 Symptoms and signs involving the urinary system
0.965 0.035 0.000
T81 Complications of procedures, not elsewhere classified
0.963 0.037 0.000
Chapter X Diseases of the respiratory system
0.962 0.038 0.000
I73.9 Peripheral vascular disease, unspecified
0.958 0.042 0.000
J20-J22 Other acute lower respiratory infections
0.951 0.049 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.951 0.049 0.000
J22 Unspecified acute lower respiratory infection
0.942 0.058 0.000
D25 Leiomyoma of uterus
0.941 0.059 0.000
D12.2 Ascending colon
0.941 0.059 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.941 0.059 0.000
M19 Other arthrosis
0.939 0.061 0.000
A30-A49 Other bacterial diseases
0.938 0.062 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.938 0.062 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.938 0.062 0.000
Z86.5 Personal history of other mental and behavioural disorders
0.937 0.063 0.000
Chapter VII Diseases of the eye and adnexa
0.937 0.063 0.000
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified
0.930 0.070 0.000
R32 Unspecified urinary incontinence
0.929 0.071 0.000
D12.0 Caecum
0.928 0.072 0.000
M17 Gonarthrosis [arthrosis of knee]
0.927 0.073 0.000
Z12 Special screening examination for neoplasms
0.926 0.074 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.923 0.077 0.000
N10-N16 Renal tubulo-interstitial diseases
0.913 0.087 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.911 0.089 0.000
S40-S49 Injuries to the shoulder and upper arm
0.910 0.090 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.908 0.092 0.000
Z86.6 Personal history of diseases of the nervous system and sense organs
0.905 0.095 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.904 0.096 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.904 0.096 0.000
N40-N51 Diseases of male genital organs
0.904 0.096 0.000
N30-N39 Other diseases of urinary system
0.900 0.100 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.900 0.100 0.000
Z87 Personal history of other diseases and conditions
0.899 0.101 0.000
E89.0 Postprocedural hypothyroidism
0.899 0.101 0.000
C34.1 Upper lobe, bronchus or lung
0.899 0.101 0.000
A41 Other septicaemia
0.899 0.101 0.000
I73.0 Raynaud's syndrome
0.898 0.102 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.897 0.103 0.000
D12.5 Sigmoid colon
0.897 0.103 0.000
W00-W19 Falls
0.896 0.104 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.896 0.104 0.000
T81.4 Infection following a procedure, not elsewhere classified
0.895 0.105 0.000
C34.3 Lower lobe, bronchus or lung
0.891 0.109 0.000
Chapter VI Diseases of the nervous system
0.891 0.109 0.000
E78.5 Hyperlipidaemia, unspecified
0.889 0.111 0.000
N43 Hydrocele and spermatocele
0.889 0.111 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.888 0.112 0.000
R39 Other symptoms and signs involving the urinary system
0.882 0.118 0.000
Z85 Personal history of malignant neoplasm
0.879 0.121 0.000
Z03 Medical observation and evaluation for suspected diseases and conditions
0.878 0.122 0.000
N43.3 Hydrocele, unspecified
0.878 0.122 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.876 0.124 0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.875 0.125 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.874 0.126 0.000
Z12.1 Special screening examination for neoplasm of intestinal tract
0.874 0.126 0.000
Z95.1 Presence of aortocoronary bypass graft
0.873 0.127 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.872 0.128 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.870 0.130 0.000
L85 Other epidermal thickening
0.870 0.130 0.000
Chapter V Mental and behavioural disorders
0.867 0.133 0.000
C64-C68 Malignant neoplasms of urinary tract
0.866 0.134 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.865 0.135 0.000
D25.1 Intramural leiomyoma of uterus
0.864 0.136 0.000
D60-D64 Aplastic and other anaemias
0.860 0.140 0.000
D12.8 Rectum
0.854 0.146 0.000
E20-E35 Disorders of other endocrine glands
0.852 0.148 0.000
I10-I15 Hypertensive diseases
0.850 0.150 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.849 0.151 0.000
R33 Retention of urine
0.849 0.151 0.000
L98.8 Other specified disorders of skin and subcutaneous tissue
0.849 0.151 0.000
D12.6 Colon, unspecified
0.848 0.152 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.847 0.153 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.846 0.154 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.844 0.156 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.844 0.156 0.000
D25.0 Submucous leiomyoma of uterus
0.843 0.157 0.000
M19.9 Arthrosis, unspecified
0.842 0.158 0.000
E86 Volume depletion
0.841 0.159 0.000
M17.1 Other primary gonarthrosis
0.840 0.160 0.000
M70-M79 Other soft tissue disorders
0.839 0.160 0.000
R42 Dizziness and giddiness
0.839 0.161 0.000
M16.0 Primary coxarthrosis, bilateral
0.838 0.162 0.000
Z29 Need for other prophylactic measures
0.837 0.163 0.000
Z96 Presence of other functional implants
0.836 0.164 0.000
N13 Obstructive and reflux uropathy
0.836 0.164 0.000
G40-G47 Episodic and paroxysmal disorders
0.832 0.168 0.000
I60-I69 Cerebrovascular diseases
0.832 0.168 0.000
Z94 Transplanted organ and tissue status
0.830 0.170 0.000
L98.9 Disorder of skin and subcutaneous tissue, unspecified
0.829 0.171 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.829 0.171 0.000
W19 Unspecified fall
0.828 0.172 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.826 0.174 0.000
I74 Arterial embolism and thrombosis
0.826 0.174 0.000
D35 Benign neoplasm of other and unspecified endocrine glands
0.825 0.175 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.823 0.177 0.000
M19.0 Primary arthrosis of other joints
0.823 0.177 0.000
Z22 Carrier of infectious disease
0.823 0.177 0.000
M05-M14 Inflammatory polyarthropathies
0.819 0.181 0.000
N32 Other disorders of bladder
0.819 0.181 0.000
N20-N23 Urolithiasis
0.818 0.182 0.000
L91 Hypertrophic disorders of skin
0.817 0.183 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.816 0.184 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.814 0.186 0.000
A41.5 Septicaemia due to other Gram-negative organisms
0.814 0.186 0.000
A41.9 Septicaemia, unspecified
0.813 0.187 0.000
T86 Failure and rejection of transplanted organs and tissues
0.808 0.192 0.000
M20-M25 Other joint disorders
0.808 0.192 0.000
R39.1 Other difficulties with micturition
0.807 0.193 0.000
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters
0.807 0.193 0.000
S00-S09 Injuries to the head
0.807 0.193 0.000
L89 Decubitus ulcer
0.807 0.193 0.000
D45 Polycythaemia vera
0.805 0.195 0.000
N60-N64 Disorders of breast
0.805 0.195 0.000
D73 Diseases of spleen
0.805 0.195 0.000
H40-H42 Glaucoma
0.804 0.196 0.000
D47.3 Essential (haemorrhagic) thrombocythaemia
0.804 0.196 0.000
C51-C58 Malignant neoplasms of female genital organs
0.803 0.197 0.000
B35-B49 Mycoses
0.801 0.199 0.000
M40-M43 Deforming dorsopathies
0.801 0.199 0.000
Z93 Artificial opening status
0.799 0.201 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.798 0.202 0.000
Z89 Acquired absence of limb
0.797 0.203 0.000
Z87.3 Personal history of diseases of the musculoskeletal system and connective tissue
0.797 0.203 0.000
C15-C26 Malignant neoplasms of digestive organs
0.795 0.205 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.794 0.206 0.000
D10 Benign neoplasm of mouth and pharynx
0.792 0.208 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.790 0.210 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.790 0.210 0.000
E10-E14 Diabetes mellitus
0.789 0.211 0.000
H50 Other strabismus
0.789 0.211 0.000
L85.9 Epidermal thickening, unspecified
0.788 0.211 0.000
Chapter XXII Codes for special purposes
0.788 0.212 0.000
D34 Benign neoplasm of thyroid gland
0.787 0.213 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.782 0.218 0.000
D36 Benign neoplasm of other and unspecified sites
0.781 0.219 0.000
N13.3 Other and unspecified hydronephrosis
0.780 0.220 0.000
W20-W49 Exposure to inanimate mechanical forces
0.779 0.221 0.000
E83 Disorders of mineral metabolism
0.778 0.222 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.778 0.222 0.000
N48 Other disorders of penis
0.777 0.223 0.000
N99-N99 Other disorders of the genitourinary system
0.776 0.224 0.000
G43 Migraine
0.776 0.224 0.000
Z91.5 Personal history of self-harm
0.775 0.225 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.775 0.225 0.000
C67 Malignant neoplasm of bladder
0.774 0.226 0.000
D75 Other diseases of blood and blood-forming organs
0.774 0.226 0.000
S20-S29 Injuries to the thorax
0.770 0.230 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.770 0.230 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.770 0.230 0.000
D12.4 Descending colon
0.769 0.231 0.000
R35 Polyuria
0.769 0.231 0.000
Z83 Family history of other specific disorders
0.769 0.231 0.000
I10 Essential (primary) hypertension
0.768 0.232 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.768 0.232 0.000
C80 Malignant neoplasm without specification of site
0.768 0.232 0.000
L82 Seborrhoeic keratosis
0.767 0.233 0.000
W19.9 Unspecified place
0.765 0.235 0.000
D47.1 Chronic myeloproliferative disease
0.764 0.236 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.764 0.236 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.763 0.237 0.000
Z85.1 Personal history of malignant neoplasm of trachea, bronchus and lung
0.763 0.237 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.763 0.237 0.000
Z03.1 Observation for suspected malignant neoplasm
0.761 0.239 0.000
M45-M49 Spondylopathies
0.761 0.239 0.000
Z87.1 Personal history of diseases of the digestive system
0.760 0.240 0.000
Z85.5 Personal history of malignant neoplasm of urinary tract
0.760 0.240 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.759 0.240 0.000
S42 Fracture of shoulder and upper arm
0.759 0.241 0.000
D21 Other benign neoplasms of connective and other soft tissue
0.757 0.243 0.000
S70-S79 Injuries to the hip and thigh
0.757 0.243 0.000
C77.3 Axillary and upper limb lymph nodes
0.757 0.243 0.000
N32.8 Other specified disorders of bladder
0.756 0.244 0.000
Z85.8 Personal history of malignant neoplasms of other organs and systems
0.755 0.245 0.000
Z08.0 Follow-up examination after surgery for malignant neoplasm
0.755 0.245 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.755 0.245 0.000
J60-J70 Lung diseases due to external agents
0.754 0.246 0.000
T90 Sequelae of injuries of head
0.754 0.246 0.000
C77.1 Intrathoracic lymph nodes
0.753 0.247 0.000
Z13 Special screening examination for other diseases and disorders
0.753 0.247 0.000
S40 Superficial injury of shoulder and upper arm
0.753 0.247 0.000
Z80 Family history of malignant neoplasm
0.753 0.247 0.000
E87.5 Hyperkalaemia
0.751 0.249 0.000
E78.2 Mixed hyperlipidaemia
0.751 0.249 0.000
Z03.8 Observation for other suspected diseases and conditions
0.751 0.249 0.000
Z60 Problems related to social environment
0.749 0.250 0.000
N20 Calculus of kidney and ureter
0.749 0.251 0.000
L81 Other disorders of pigmentation
0.748 0.252 0.000
M19.99 Arthrosis, unspecified (Site unspecified)
0.747 0.253 0.000
D41.4 Bladder
0.747 0.253 0.000
I77 Other disorders of arteries and arterioles
0.747 0.253 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.746 0.254 0.000
C77.9 Lymph node, unspecified
0.746 0.254 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.745 0.255 0.000
D00-D09 In situ neoplasms
0.745 0.255 0.000
D25.2 Subserosal leiomyoma of uterus
0.745 0.255 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.743 0.257 0.000
L50-L54 Urticaria and erythema
0.742 0.257 0.000
I71 Aortic aneurysm and dissection
0.742 0.258 0.000
T66-T78 Other and unspecified effects of external causes
0.742 0.258 0.000
D12.3 Transverse colon
0.742 0.258 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.741 0.259 0.000
M17.0 Primary gonarthrosis, bilateral
0.739 0.261 0.000
V20-V29 Motorcycle rider injured in transport accident
0.739 0.261 0.000
S90-S99 Injuries to the ankle and foot
0.739 0.261 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.738 0.262 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
0.738 0.262 0.000
J20 Acute bronchitis
0.738 0.262 0.000
Z03.5 Observation for other suspected cardiovascular diseases
0.736 0.264 0.000
I72 Other aneurysm
0.736 0.264 0.000
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified
0.736 0.264 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.735 0.265 0.000
Z04 Examination and observation for other reasons
0.734 0.265 0.000
F60-F69 Disorders of adult personality and behaviour
0.734 0.266 0.000
Z86.0 Personal history of other neoplasms
0.734 0.266 0.000
Z82.5 Family history of asthma and other chronic lower respiratory diseases
0.733 0.267 0.000
Z86.3 Personal history of endocrine, nutritional and metabolic diseases
0.733 0.267 0.000
S50-S59 Injuries to the elbow and forearm
0.732 0.268 0.000
T79-T79 Certain early complications of trauma
0.732 0.268 0.000
Z96.6 Presence of orthopaedic joint implants
0.731 0.269 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.731 0.269 0.000
L90 Atrophic disorders of skin
0.731 0.269 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.731 0.269 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.729 0.271 0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.729 0.271 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.729 0.271 0.000
N25-N29 Other disorders of kidney and ureter
0.728 0.272 0.000
T93 Sequelae of injuries of lower limb
0.728 0.272 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.728 0.272 0.000
X60-X84 Intentional self-harm
0.728 0.272 0.000
Z90.1 Acquired absence of breast(s)
0.727 0.273 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.727 0.273 0.000
Z29.2 Other prophylactic chemotherapy
0.727 0.273 0.000
N39 Other disorders of urinary system
0.725 0.275 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.725 0.275 0.000
D68 Other coagulation defects
0.725 0.275 0.000
D32 Benign neoplasm of meninges
0.724 0.276 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.724 0.276 0.000
M86-M90 Other osteopathies
0.724 0.276 0.000
J95-J99 Other diseases of the respiratory system
0.724 0.276 0.000
V10-V19 Pedal cyclist injured in transport accident
0.723 0.277 0.000
C77.4 Inguinal and lower limb lymph nodes
0.723 0.277 0.000
E87.0 Hyperosmolality and hypernatraemia
0.722 0.278 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.722 0.278 0.000
Y57 Other and unspecified drugs and medicaments
0.721 0.279 0.000
D23 Other benign neoplasms of skin
0.721 0.279 0.000
C50-C50 Malignant neoplasm of breast
0.720 0.280 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.719 0.280 0.000
Z90.8 Acquired absence of other organs
0.718 0.282 0.000
Z08.7 Follow-up examination after combined treatment for malignant neoplasm
0.717 0.282 0.000
Z84 Family history of other conditions
0.717 0.283 0.000
Z81 Family history of mental and behavioural disorders
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.717 0.283 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
M91-M94 Chondropathies
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
Z90.2 Acquired absence of lung [part of]
0.717 0.283 0.000
D31 Benign neoplasm of eye and adnexa
0.716 0.283 0.000
D30 Benign neoplasm of urinary organs
0.716 0.283 0.000
D29 Benign neoplasm of male genital organs
0.716 0.283 0.000
D28 Benign neoplasm of other and unspecified female genital organs
0.716 0.283 0.000
D26 Other benign neoplasms of uterus
0.716 0.283 0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum
0.716 0.283 0.000
D19 Benign neoplasm of mesothelial tissue
0.716 0.283 0.000
D16 Benign neoplasm of bone and articular cartilage
0.716 0.283 0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs
0.716 0.283 0.000
D14 Benign neoplasm of middle ear and respiratory system
0.716 0.283 0.000
D11 Benign neoplasm of major salivary glands
0.716 0.283 0.000
T33-T35 Frostbite
0.716 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.716 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.716 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.716 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.716 0.283 0.000
S10-S19 Injuries to the neck
0.716 0.283 0.000
M15 Polyarthrosis
0.716 0.284 0.000
D12.9 Anus and anal canal
0.715 0.284 0.000
D12.1 Appendix
0.715 0.284 0.000
Z10 Routine general health check-up of defined subpopulation
0.715 0.284 0.000
G43.9 Migraine, unspecified
0.715 0.285 0.000
E40-E46 Malnutrition
0.714 0.285 0.000
G40 Epilepsy
0.714 0.286 0.000
B99-B99 Other infectious diseases
0.713 0.287 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.713 0.287 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.713 0.287 0.000
B65-B83 Helminthiases
0.713 0.287 0.000
B50-B64 Protozoal diseases
0.713 0.287 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.713 0.287 0.000
B15-B19 Viral hepatitis
0.713 0.287 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.713 0.287 0.000
A80-A89 Viral infections of the central nervous system
0.713 0.287 0.000
A75-A79 Rickettsioses
0.713 0.287 0.000
A70-A74 Other diseases caused by chlamydiae
0.713 0.287 0.000
A65-A69 Other spirochaetal diseases
0.713 0.287 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.713 0.287 0.000
A20-A28 Certain zoonotic bacterial diseases
0.713 0.287 0.000
A15-A19 Tuberculosis
0.713 0.287 0.000
Z91.6 Personal history of other physical trauma
0.713 0.287 0.000
D35.1 Parathyroid gland
0.713 0.287 0.000
M18 Arthrosis of first carpometacarpal joint
0.713 0.287 0.000
D24 Benign neoplasm of breast
0.713 0.287 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.713 0.287 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.713 0.287 0.000
C32 Malignant neoplasm of larynx
0.713 0.287 0.000
C31 Malignant neoplasm of accessory sinuses
0.713 0.287 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.713 0.287 0.000
C37 Malignant neoplasm of thymus
0.713 0.287 0.000
C33 Malignant neoplasm of trachea
0.713 0.287 0.000
R45 Symptoms and signs involving emotional state
0.713 0.287 0.000
M80-M85 Disorders of bone density and structure
0.712 0.288 0.000
E88 Other metabolic disorders
0.712 0.288 0.000
E85 Amyloidosis
0.712 0.288 0.000
E84 Cystic fibrosis
0.712 0.288 0.000
E79 Disorders of purine and pyrimidine metabolism
0.712 0.288 0.000
E77 Disorders of glycoprotein metabolism
0.712 0.288 0.000
E76 Disorders of glycosaminoglycan metabolism
0.712 0.288 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.712 0.288 0.000
E74 Other disorders of carbohydrate metabolism
0.712 0.288 0.000
E73 Lactose intolerance
0.712 0.288 0.000
E72 Other disorders of amino-acid metabolism
0.712 0.288 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.712 0.288 0.000
E70 Disorders of aromatic amino-acid metabolism
0.712 0.288 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.712 0.288 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.711 0.289 0.000
Y35-Y36 Legal intervention and operations of war
0.711 0.289 0.000
Y10-Y34 Event of undetermined intent
0.711 0.289 0.000
Y00-Y09 Assault
0.711 0.289 0.000
X85-X99 Assault
0.711 0.289 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.711 0.289 0.000
X50-X57 Overexertion, travel and privation
0.711 0.289 0.000
X30-X39 Exposure to forces of nature
0.711 0.289 0.000
X20-X29 Contact with venomous animals and plants
0.711 0.289 0.000
X10-X19 Contact with heat and hot substances
0.711 0.289 0.000
X00-X09 Exposure to smoke, fire and flames
0.711 0.289 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.711 0.289 0.000
W75-W84 Other accidental threats to breathing
0.711 0.289 0.000
W65-W74 Accidental drowning and submersion
0.711 0.289 0.000
W50-W64 Exposure to animate mechanical forces
0.711 0.289 0.000
V98-V99 Other and unspecified transport accidents
0.711 0.289 0.000
V95-V97 Air and space transport accidents
0.711 0.289 0.000
V90-V94 Water transport accidents
0.711 0.289 0.000
V80-V89 Other land transport accidents
0.711 0.289 0.000
V70-V79 Bus occupant injured in transport accident
0.711 0.289 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.711 0.289 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.711 0.289 0.000
V40-V49 Car occupant injured in transport accident
0.711 0.289 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.711 0.289 0.000
V01-V09 Pedestrian injured in transport accident
0.711 0.289 0.000
Z22.3 Carrier of other specified bacterial diseases
0.710 0.290 0.000
C34.8 Overlapping lesion of bronchus and lung
0.710 0.290 0.000
C34.2 Middle lobe, bronchus or lung
0.710 0.290 0.000
C34.0 Main bronchus
0.710 0.290 0.000
I00-I02 Acute rheumatic fever
0.710 0.290 0.000
I60 Subarachnoid haemorrhage
0.709 0.291 0.000
M17.9 Gonarthrosis, unspecified
0.709 0.291 0.000
H40 Glaucoma
0.709 0.291 0.000
L10-L14 Bullous disorders
0.708 0.292 0.000
T87 Complications peculiar to reattachment and amputation
0.708 0.292 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.708 0.292 0.000
H55-H59 Other disorders of eye and adnexa
0.708 0.292 0.000
D61 Other aplastic anaemias
0.708 0.292 0.000
C77.8 Lymph nodes of multiple regions
0.707 0.293 0.000
M13 Other arthritis
0.706 0.294 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.706 0.294 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.706 0.294 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.705 0.294 0.000
M16.7 Other secondary coxarthrosis
0.705 0.294 0.000
M16.6 Other secondary coxarthrosis, bilateral
0.705 0.294 0.000
M16.5 Other posttraumatic coxarthrosis
0.705 0.294 0.000
M16.4 Posttraumatic coxarthrosis, bilateral
0.705 0.294 0.000
M16.3 Other dysplastic coxarthrosis
0.705 0.294 0.000
M16.2 Coxarthrosis resulting from dysplasia, bilateral
0.705 0.294 0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.705 0.295 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.705 0.295 0.000
L94 Other localised connective tissue disorders
0.705 0.295 0.000
L93 Lupus erythematosus
0.705 0.295 0.000
L87 Transepidermal elimination disorders
0.705 0.295 0.000
L88 Pyoderma gangrenosum
0.705 0.295 0.000
L86 Keratoderma in diseases classified elsewhere
0.705 0.295 0.000
L84 Corns and callosities
0.705 0.295 0.000
L83 Acanthosis nigricans
0.705 0.295 0.000
L80 Vitiligo
0.705 0.295 0.000
M65-M68 Disorders of synovium and tendon
0.705 0.295 0.000
E50-E64 Other nutritional deficiencies
0.705 0.295 0.000
N36 Other disorders of urethra
0.705 0.295 0.000
Z91.0 Personal history of allergy, other than to drugs and biological substances
0.705 0.295 0.000
Z93.3 Colostomy status
0.704 0.296 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.703 0.297 0.000
C77.5 Intrapelvic lymph nodes
0.703 0.297 0.000
D46 Myelodysplastic syndromes
0.702 0.298 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.702 0.298 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.702 0.298 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.702 0.298 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.702 0.298 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.702 0.298 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.702 0.298 0.000
R50-R69 General symptoms and signs
0.702 0.298 0.000
S06 Intracranial injury
0.702 0.298 0.000
Y40 Systemic antibiotics
0.702 0.298 0.000
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters
0.702 0.298 0.000
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters
0.702 0.298 0.000
B96.0 Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified to other chapters
0.702 0.298 0.000
C73 Malignant neoplasm of thyroid gland
0.701 0.299 0.000
D22 Melanocytic naevi
0.701 0.299 0.000
I73.8 Other specified peripheral vascular diseases
0.700 0.300 0.000
I73.1 Thromboangiitis obliterans [Buerger]
0.700 0.300 0.000
D12.7 Rectosigmoid junction
0.700 0.300 0.000
Z09.7 Follow-up examination after combined treatment for other conditions
0.700 0.300 0.000
Z09.4 Follow-up examination after treatment of fracture
0.700 0.300 0.000
Z09.3 Follow-up examination after psychotherapy
0.700 0.300 0.000
Z09.1 Follow-up examination after radiotherapy for other conditions
0.700 0.300 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.699 0.301 0.000
H49 Paralytic strabismus
0.699 0.301 0.000
L91.8 Other hypertrophic disorders of skin
0.698 0.302 0.000
S60-S69 Injuries to the wrist and hand
0.698 0.302 0.000
T92 Sequelae of injuries of upper limb
0.696 0.304 0.000
D80-D89 Certain disorders involving the immune mechanism
0.695 0.304 0.000
D55-D59 Haemolytic anaemias
0.695 0.304 0.000
D62 Acute posthaemorrhagic anaemia
0.695 0.305 0.000
D13 Benign neoplasm of other and ill-defined parts of digestive system
0.695 0.305 0.000
N41 Inflammatory diseases of prostate
0.695 0.305 0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters
0.694 0.306 0.000
H10-H13 Disorders of conjunctiva
0.693 0.307 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.693 0.307 0.000
G81 Hemiplegia
0.693 0.307 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.693 0.307 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.692 0.307 0.000
J09-J18 Influenza and pneumonia
0.692 0.308 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.692 0.308 0.000
R36 Urethral discharge
0.692 0.308 0.000
R34 Anuria and oliguria
0.692 0.308 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.691 0.308 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.691 0.308 0.000
D70 Agranulocytosis
0.691 0.309 0.000
T81.9 Unspecified complication of procedure
0.690 0.310 0.000
T81.7 Vascular complications following a procedure, not elsewhere classified
0.690 0.310 0.000
T81.6 Acute reaction to foreign substance accidentally left during a procedure
0.690 0.310 0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure
0.690 0.310 0.000
T81.1 Shock during or resulting from a procedure, not elsewhere classified
0.690 0.310 0.000
N63 Unspecified lump in breast
0.690 0.310 0.000
C67.9 Bladder, unspecified
0.690 0.310 0.000
H50.1 Divergent concomitant strabismus
0.690 0.310 0.000
I95 Hypotension
0.689 0.311 0.000
H52 Disorders of refraction and accommodation
0.689 0.311 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.689 0.311 0.000
Y85 Sequelae of transport accidents
0.688 0.312 0.000
M24 Other specific joint derangements
0.688 0.312 0.000
D33 Benign neoplasm of brain and other parts of central nervous system
0.688 0.312 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.687 0.313 0.000
J30-J39 Other diseases of upper respiratory tract
0.687 0.313 0.000
R39.8 Other and unspecified symptoms and signs involving the urinary system
0.687 0.313 0.000
Z86.2 Personal history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.686 0.313 0.000
R30 Pain associated with micturition
0.686 0.314 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.686 0.314 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.686 0.314 0.000
D47.2 Monoclonal gammopathy
0.685 0.314 0.000
H53-H54 Visual disturbances and blindness
0.685 0.315 0.000
E11 Non-insulin-dependent diabetes mellitus
0.685 0.315 0.000
Z94.8 Other transplanted organ and tissue status
0.684 0.316 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.684 0.316 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.684 0.316 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.684 0.316 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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