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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs117114876
log Bayes Factor = 16.6508
Chromosome 14   position 73,422,219  (GRCh37) Explore rs117114876 on Ensembl!
Variant rs117114876 is part of Cluster X0039

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
I10-I15 Hypertensive diseases
0.998 0.002 0.000
Chapter VII Diseases of the eye and adnexa
0.997 0.003 0.000
M05-M14 Inflammatory polyarthropathies
0.996 0.004 0.000
Chapter X Diseases of the respiratory system
0.995 0.005 0.000
Chapter II Neoplasms
0.991 0.009 0.000
M06 Other rheumatoid arthritis
0.991 0.009 0.000
I20-I25 Ischaemic heart diseases
0.991 0.009 0.000
I21.9 Acute myocardial infarction, unspecified
0.990 0.010 0.000
I21 Acute myocardial infarction
0.989 0.011 0.000
Chapter XXI Factors influencing health status and contact with health services
0.987 0.013 0.000
M06.9 Rheumatoid arthritis, unspecified
0.983 0.017 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.983 0.017 0.000
I30-I52 Other forms of heart disease
0.982 0.018 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.980 0.020 0.000
I12 Hypertensive renal disease
0.979 0.021 0.000
J40-J47 Chronic lower respiratory diseases
0.978 0.022 0.000
Chapter XIV Diseases of the genitourinary system
0.974 0.026 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.968 0.032 0.000
I60-I69 Cerebrovascular diseases
0.968 0.032 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.967 0.033 0.000
I10 Essential (primary) hypertension
0.967 0.033 0.000
E10-E14 Diabetes mellitus
0.961 0.039 0.000
H40-H42 Glaucoma
0.957 0.043 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.956 0.044 0.000
N17-N19 Renal failure
0.953 0.047 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.951 0.049 0.000
J44 Other chronic obstructive pulmonary disease
0.950 0.050 0.000
Z50 Care involving use of rehabilitation procedures
0.948 0.052 0.000
H30-H36 Disorders of choroid and retina
0.948 0.052 0.000
I12.0 Hypertensive renal disease with renal failure
0.942 0.058 0.000
I35 Nonrheumatic aortic valve disorders
0.942 0.058 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.934 0.066 0.000
Z53 Persons encountering health services for specifie procedures, not carried out
0.930 0.070 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.930 0.070 0.000
H40 Glaucoma
0.928 0.072 0.000
J43 Emphysema
0.926 0.074 0.000
N18 Chronic renal failure
0.924 0.076 0.000
N10-N16 Renal tubulo-interstitial diseases
0.920 0.080 0.000
D10-D36 Benign neoplasms
0.920 0.080 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.918 0.082 0.000
J90-J94 Other diseases of pleura
0.917 0.083 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.913 0.087 0.000
E10 Insulin-dependent diabetes mellitus
0.905 0.095 0.000
N20-N23 Urolithiasis
0.904 0.096 0.000
I38 Endocarditis, valve unspecified
0.902 0.098 0.000
Chapter I Certain infectious and parasitic diseases
0.899 0.101 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.898 0.102 0.000
Z60 Problems related to social environment
0.896 0.104 0.000
Z53.9 Procedure not carried out, unspecified reason
0.895 0.105 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.891 0.109 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.889 0.111 0.000
J43.9 Emphysema, unspecified
0.889 0.111 0.000
N13 Obstructive and reflux uropathy
0.888 0.112 0.000
E14 Unspecified diabetes mellitus
0.883 0.117 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.881 0.119 0.000
I12.9 Hypertensive renal disease without renal failure
0.879 0.121 0.000
A30-A49 Other bacterial diseases
0.879 0.121 0.000
D17 Benign lipomatous neoplasm
0.879 0.121 0.000
D27 Benign neoplasm of ovary
0.876 0.124 0.000
H40.1 Primary open-angle glaucoma
0.876 0.124 0.000
Z50.1 Other physical therapy
0.871 0.129 0.000
I35.1 Aortic (valve) insufficiency
0.871 0.129 0.000
Z60.2 Living alone
0.869 0.131 0.000
M40-M43 Deforming dorsopathies
0.869 0.131 0.000
E11 Non-insulin-dependent diabetes mellitus
0.867 0.133 0.000
A41 Other septicaemia
0.866 0.134 0.000
S80-S89 Injuries to the knee and lower leg
0.865 0.135 0.000
M70-M79 Other soft tissue disorders
0.862 0.138 0.000
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified
0.861 0.139 0.000
Z41 Procedures for purposes other than remedying health state
0.860 0.140 0.000
L82 Seborrhoeic keratosis
0.859 0.141 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.858 0.142 0.000
D60-D64 Aplastic and other anaemias
0.854 0.146 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.853 0.147 0.000
Chapter V Mental and behavioural disorders
0.852 0.148 0.000
N20 Calculus of kidney and ureter
0.852 0.148 0.000
M13 Other arthritis
0.851 0.149 0.000
J90 Pleural effusion, not elsewhere classified
0.851 0.149 0.000
M80-M85 Disorders of bone density and structure
0.848 0.152 0.000
I67 Other cerebrovascular diseases
0.848 0.152 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.846 0.154 0.000
D00-D09 In situ neoplasms
0.844 0.156 0.000
H36 Retinal disorders in diseases classified elsewhere
0.844 0.156 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.844 0.156 0.000
I61 Intracerebral haemorrhage
0.843 0.157 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.841 0.159 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.838 0.162 0.000
I45 Other conduction disorders
0.833 0.167 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.831 0.169 0.000
Z46 Fitting and adjustment of other devices
0.831 0.169 0.000
N18.9 Chronic renal failure, unspecified
0.831 0.169 0.000
Z53.0 Procedure not carried out because of contraindication
0.830 0.170 0.000
I46 Cardiac arrest
0.829 0.171 0.000
M86-M90 Other osteopathies
0.829 0.171 0.000
A41.9 Septicaemia, unspecified
0.829 0.171 0.000
C15-C26 Malignant neoplasms of digestive organs
0.828 0.172 0.000
L91 Hypertrophic disorders of skin
0.826 0.174 0.000
N19 Unspecified renal failure
0.824 0.176 0.000
H02 Other disorders of eyelid
0.824 0.176 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.824 0.176 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.824 0.176 0.000
D70 Agranulocytosis
0.821 0.179 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.821 0.179 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.820 0.180 0.000
H34 Retinal vascular occlusions
0.819 0.181 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.818 0.182 0.000
L85 Other epidermal thickening
0.816 0.184 0.000
N13.5 Kinking and stricture of ureter without hydronephrosis
0.813 0.187 0.000
M06.0 Seronegative rheumatoid arthritis
0.812 0.188 0.000
I73 Other peripheral vascular diseases
0.810 0.190 0.000
E10.9 Without complications
0.810 0.190 0.000
J42 Unspecified chronic bronchitis
0.806 0.194 0.000
M75 Shoulder lesions
0.805 0.195 0.000
H40.9 Glaucoma, unspecified
0.803 0.197 0.000
I50 Heart failure
0.803 0.197 0.000
N18.4 Chronic kidney disease, stage 4
0.801 0.199 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.800 0.200 0.000
E10.3 With ophthalmic complications
0.800 0.200 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.799 0.201 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.799 0.201 0.000
I21.4 Acute subendocardial myocardial infarction
0.798 0.202 0.000
I62 Other nontraumatic intracranial haemorrhage
0.797 0.203 0.000
L40-L45 Papulosquamous disorders
0.797 0.203 0.000
I15 Secondary hypertension
0.791 0.209 0.000
Chapter XXII Codes for special purposes
0.791 0.209 0.000
M45-M49 Spondylopathies
0.790 0.210 0.000
H55-H59 Other disorders of eye and adnexa
0.789 0.211 0.000
D62 Acute posthaemorrhagic anaemia
0.787 0.213 0.000
M06.4 Inflammatory polyarthropathy
0.781 0.218 0.000
Z48 Other surgical follow-up care
0.781 0.219 0.000
M41 Scoliosis
0.781 0.219 0.000
D18 Haemangioma and lymphangioma, any site
0.779 0.221 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.775 0.225 0.000
N00-N08 Glomerular diseases
0.775 0.225 0.000
H02.8 Other specified disorders of eyelid
0.773 0.227 0.000
Z41.1 Other plastic surgery for unacceptable cosmetic appearance
0.772 0.228 0.000
M07 Psoriatic and enteropathic arthropathies
0.771 0.229 0.000
C79 Secondary malignant neoplasm of other sites
0.770 0.230 0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction
0.769 0.230 0.000
H36.0 Diabetic retinopathy
0.769 0.231 0.000
E14.3 With ophthalmic complications
0.769 0.231 0.000
J60-J70 Lung diseases due to external agents
0.768 0.232 0.000
N20.0 Calculus of kidney
0.767 0.233 0.000
I73.9 Peripheral vascular disease, unspecified
0.766 0.234 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.765 0.235 0.000
C51-C58 Malignant neoplasms of female genital organs
0.765 0.235 0.000
M05 Seropositive rheumatoid arthritis
0.764 0.236 0.000
M60-M63 Disorders of muscles
0.763 0.237 0.000
H35 Other retinal disorders
0.763 0.237 0.000
M91-M94 Chondropathies
0.763 0.237 0.000
E14.9 Without complications
0.762 0.238 0.000
J30-J39 Other diseases of upper respiratory tract
0.762 0.238 0.000
I33 Acute and subacute endocarditis
0.761 0.239 0.000
Z45 Adjustment and management of implanted device
0.760 0.239 0.000
N20.1 Calculus of ureter
0.760 0.240 0.000
S50-S59 Injuries to the elbow and forearm
0.759 0.241 0.000
M00-M03 Infectious arthropathies
0.759 0.241 0.000
D17.6 Benign lipomatous neoplasm of spermatic cord
0.758 0.242 0.000
Chapter XX External causes of morbidity and mortality
0.757 0.243 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.756 0.244 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.755 0.245 0.000
S82 Fracture of lower leg, including ankle
0.754 0.246 0.000
I61.9 Intracerebral haemorrhage, unspecified
0.754 0.246 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.753 0.247 0.000
N23 Unspecified renal colic
0.753 0.247 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.753 0.247 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.751 0.249 0.000
I63 Cerebral infarction
0.750 0.250 0.000
M75.4 Impingement syndrome of shoulder
0.749 0.251 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.748 0.252 0.000
J00-J06 Acute upper respiratory infections
0.748 0.252 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.748 0.252 0.000
I67.8 Other specified cerebrovascular diseases
0.746 0.254 0.000
I35.0 Aortic (valve) stenosis
0.745 0.255 0.000
J92 Pleural plaque
0.745 0.255 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.745 0.255 0.000
Z50.8 Care involving use of rehabilitation procedures
0.743 0.256 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.743 0.257 0.000
N18.0 End-stage renal disease
0.741 0.259 0.000
I42 Cardiomyopathy
0.740 0.260 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.739 0.261 0.000
C73 Malignant neoplasm of thyroid gland
0.738 0.262 0.000
Z50.5 Speech therapy
0.736 0.264 0.000
A41.0 Septicaemia due to Staphylococcus aureus
0.736 0.264 0.000
D17.1 Benign lipomatous neoplasm of skin and subcutaneous tissue of trunk
0.735 0.265 0.000
S80 Superficial injury of lower leg
0.733 0.267 0.000
I50.1 Left ventricular failure
0.733 0.267 0.000
Z49 Care involving dialysis
0.732 0.268 0.000
H40.2 Primary angle-closure glaucoma
0.732 0.268 0.000
I47 Paroxysmal tachycardia
0.731 0.269 0.000
N99-N99 Other disorders of the genitourinary system
0.731 0.269 0.000
D80-D89 Certain disorders involving the immune mechanism
0.729 0.271 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.727 0.272 0.000
I11 Hypertensive heart disease
0.727 0.273 0.000
D22 Melanocytic naevi
0.726 0.274 0.000
S90-S99 Injuries to the ankle and foot
0.726 0.274 0.000
N13.3 Other and unspecified hydronephrosis
0.725 0.275 0.000
M13.9 Arthritis, unspecified
0.725 0.275 0.000
I30 Acute pericarditis
0.724 0.276 0.000
H01 Other inflammation of eyelid
0.724 0.276 0.000
M11 Other crystal arthropathies
0.724 0.276 0.000
H10-H13 Disorders of conjunctiva
0.723 0.277 0.000
Z46.8 Fitting and adjustment of other specified devices
0.723 0.277 0.000
S82.8 Fractures of other parts of lower leg
0.723 0.277 0.000
D26 Other benign neoplasms of uterus
0.723 0.277 0.000
D16 Benign neoplasm of bone and articular cartilage
0.722 0.278 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.721 0.279 0.000
E16 Other disorders of pancreatic internal secretion
0.720 0.280 0.000
F03 Unspecified dementia
0.720 0.280 0.000
C64-C68 Malignant neoplasms of urinary tract
0.720 0.280 0.000
Z54 Convalescence
0.720 0.280 0.000
D05 Carcinoma in situ of breast
0.720 0.280 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.720 0.280 0.000
M20-M25 Other joint disorders
0.719 0.280 0.000
D75 Other diseases of blood and blood-forming organs
0.719 0.281 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.719 0.281 0.000
E11.5 With peripheral circulatory complications
0.718 0.282 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.718 0.282 0.000
M41.9 Scoliosis, unspecified
0.718 0.282 0.000
Z42 Follow-up care involving plastic surgery
0.717 0.282 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
E11.2 With renal complications
0.716 0.284 0.000
I13 Hypertensive heart and renal disease
0.715 0.284 0.000
M14 Arthropathies in other diseases classified elsewhere
0.714 0.285 0.000
M12 Other specific arthropathies
0.714 0.285 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.714 0.285 0.000
M08 Juvenile arthritis
0.714 0.285 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.714 0.286 0.000
D14 Benign neoplasm of middle ear and respiratory system
0.713 0.286 0.000
A41.8 Other specified septicaemia
0.713 0.287 0.000
M84 Disorders of continuity of bone
0.713 0.287 0.000
E11.1 With ketoacidosis
0.711 0.289 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.711 0.289 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.711 0.289 0.000
M06.8 Other specified rheumatoid arthritis
0.710 0.289 0.000
M06.3 Rheumatoid nodule
0.710 0.289 0.000
M06.2 Rheumatoid bursitis
0.710 0.289 0.000
M06.1 Adult-onset Still's disease
0.710 0.289 0.000
I23 Certain current complications following acute myocardial infarction
0.710 0.290 0.000
H47 Other disorders of optic [2nd] nerve and visual pathways
0.710 0.290 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.710 0.290 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.709 0.291 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.709 0.291 0.000
N18.3 Chronic kidney disease, stage 3
0.709 0.291 0.000
I46.9 Cardiac arrest, unspecified
0.709 0.291 0.000
L89 Decubitus ulcer
0.708 0.291 0.000
C32 Malignant neoplasm of larynx
0.708 0.292 0.000
E11.3 With ophthalmic complications
0.708 0.292 0.000
N10 Acute tubulo-interstitial nephritis
0.708 0.292 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.707 0.293 0.000
L60-L75 Disorders of skin appendages
0.707 0.293 0.000
I78 Diseases of capillaries
0.707 0.293 0.000
Z48.9 Surgical follow-up care, unspecified
0.707 0.293 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.706 0.293 0.000
L40 Psoriasis
0.706 0.294 0.000
J95-J99 Other diseases of the respiratory system
0.706 0.294 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.704 0.295 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.704 0.295 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.704 0.295 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.704 0.295 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.704 0.295 0.000
Z52 Donors of organs and tissues
0.704 0.295 0.000
Z44 Fitting and adjustment of external prosthetic device
0.704 0.295 0.000
I52 Other heart disorders in diseases classified elsewhere
0.704 0.296 0.000
I48 Atrial fibrillation and flutter
0.704 0.296 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.704 0.296 0.000
I41 Myocarditis in diseases classified elsewhere
0.704 0.296 0.000
I40 Acute myocarditis
0.704 0.296 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.704 0.296 0.000
I37 Pulmonary valve disorders
0.704 0.296 0.000
I36 Nonrheumatic tricuspid valve disorders
0.704 0.296 0.000
I32 Pericarditis in diseases classified elsewhere
0.704 0.296 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.704 0.296 0.000
C50-C50 Malignant neoplasm of breast
0.703 0.296 0.000
L10-L14 Bullous disorders
0.703 0.297 0.000
D10 Benign neoplasm of mouth and pharynx
0.701 0.299 0.000
J41 Simple and mucopurulent chronic bronchitis
0.701 0.299 0.000
S82.80 Fractures of other parts of lower leg (closed)
0.701 0.299 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.700 0.300 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.700 0.300 0.000
M15-M19 Arthrosis
0.698 0.302 0.000
D17.7 Benign lipomatous neoplasm of other sites
0.698 0.302 0.000
L91.8 Other hypertrophic disorders of skin
0.698 0.302 0.000
Z43 Attention to artificial openings
0.697 0.303 0.000
N11 Chronic tubulo-interstitial nephritis
0.696 0.304 0.000
E13 Other specified diabetes mellitus
0.695 0.304 0.000
Z40 Prophylactic surgery
0.694 0.306 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.694 0.306 0.000
E40-E46 Malnutrition
0.694 0.306 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.694 0.306 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.694 0.306 0.000
D11 Benign neoplasm of major salivary glands
0.693 0.306 0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.693 0.307 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.693 0.307 0.000
L94 Other localised connective tissue disorders
0.693 0.307 0.000
L93 Lupus erythematosus
0.693 0.307 0.000
L87 Transepidermal elimination disorders
0.693 0.307 0.000
L88 Pyoderma gangrenosum
0.693 0.307 0.000
L86 Keratoderma in diseases classified elsewhere
0.693 0.307 0.000
L83 Acanthosis nigricans
0.693 0.307 0.000
L80 Vitiligo
0.693 0.307 0.000
H34.2 Other retinal artery occlusions
0.693 0.307 0.000
H46 Optic neuritis
0.693 0.307 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.693 0.307 0.000
D04 Carcinoma in situ of skin
0.692 0.308 0.000
I60 Subarachnoid haemorrhage
0.692 0.308 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.692 0.308 0.000
Z63 Other problems related to primary support group, including family circumstances
0.692 0.308 0.000
E10.4 With neurological complications
0.690 0.310 0.000
E12 Malnutrition-related diabetes mellitus
0.689 0.311 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.688 0.312 0.000
I62.9 Intracranial haemorrhage (nontraumatic), unspecified
0.687 0.313 0.000
H42 Glaucoma in diseases classified elsewhere
0.686 0.314 0.000
N18.5 Chronic kidney disease, stage 5
0.686 0.314 0.000
L81 Other disorders of pigmentation
0.686 0.314 0.000
E11.6 With other specified complications
0.685 0.315 0.000
A41.5 Septicaemia due to other Gram-negative organisms
0.685 0.315 0.000
M47 Spondylosis
0.683 0.317 0.000
D73 Diseases of spleen
0.682 0.318 0.000
D17.2 Benign lipomatous neoplasm of skin and subcutaneous tissue of limbs
0.682 0.318 0.000
J40 Bronchitis, not specified as acute or chronic
0.682 0.318 0.000
H43-H45 Disorders of vitreous body and globe
0.682 0.318 0.000
D55-D59 Haemolytic anaemias
0.682 0.318 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.681 0.319 0.000
C91 Lymphoid leukaemia
0.681 0.319 0.000
Q80-Q89 Other congenital malformations
0.680 0.319 0.000
L85.8 Other specified epidermal thickening
0.680 0.320 0.000
Z50.6 Orthoptic training
0.680 0.320 0.000
Z50.4 Psychotherapy, not elsewhere classified
0.680 0.320 0.000
Z50.3 Drug rehabilitation
0.680 0.320 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.679 0.320 0.000
H31 Other disorders of choroid
0.679 0.320 0.000
H30 Chorioretinal inflammation
0.679 0.320 0.000
N18.2 Chronic kidney disease, stage 2
0.679 0.321 0.000
D18.0 Haemangioma, any site
0.679 0.321 0.000
L92.9 Granulomatous disorder of skin and subcutaneous tissue, unspecified
0.678 0.322 0.000
J09-J18 Influenza and pneumonia
0.678 0.322 0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction
0.677 0.323 0.000
Z45.8 Adjustment and management of other implanted devices
0.677 0.323 0.000
L50-L54 Urticaria and erythema
0.677 0.323 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.676 0.324 0.000
I35.8 Other aortic valve disorders
0.676 0.324 0.000
M13.94 Arthritis, unspecified (Hand)
0.674 0.326 0.000
S81 Open wound of lower leg
0.674 0.326 0.000
I35.9 Aortic valve disorder, unspecified
0.674 0.326 0.000
T79-T79 Certain early complications of trauma
0.673 0.326 0.000
N17 Acute renal failure
0.672 0.328 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.672 0.328 0.000
H33 Retinal detachments and breaks
0.671 0.329 0.000
Z65 Problems related to other psychosocial circumstances
0.669 0.330 0.000
Z64 Problems related to certain psychosocial circumstances
0.669 0.330 0.000
Z62 Other problems related to upbringing
0.669 0.330 0.000
Z61 Problems related to negative life events in childhood
0.669 0.330 0.000
Z59 Problems related to housing and economic circumstances
0.669 0.330 0.000
Z58 Problems related to physical environment
0.669 0.330 0.000
Z56 Problems related to employment and unemployment
0.669 0.330 0.000
Z55 Problems related to education and literacy
0.669 0.330 0.000
N70 Salpingitis and oophoritis
0.669 0.331 0.000
H00 Hordeolum and chalazion
0.669 0.331 0.000
D17.0 Benign lipomatous neoplasm of skin and subcutaneous tissue of head, face and neck
0.668 0.332 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.667 0.332 0.000
F80-F89 Disorders of psychological development
0.667 0.333 0.000
O26 Maternal care for other conditions predominantly related to pregnancy
0.667 0.333 0.000
N25-N29 Other disorders of kidney and ureter
0.667 0.333 0.000
I45.1 Other and unspecified right bundle-branch block
0.667 0.333 0.000
Z53.1 Procedure not carried out because of patient's decision for reasons of belief or group pressure
0.667 0.333 0.000
T33-T35 Frostbite
0.666 0.333 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.666 0.333 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.666 0.333 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.666 0.333 0.000
T00-T07 Injuries involving multiple body regions
0.666 0.333 0.000
S10-S19 Injuries to the neck
0.666 0.333 0.000
H02.5 Other disorders affecting eyelid function
0.666 0.334 0.000
H40.8 Other glaucoma
0.666 0.334 0.000
H40.6 Glaucoma secondary to drugs
0.666 0.334 0.000
H40.5 Glaucoma secondary to other eye disorders
0.666 0.334 0.000
H40.4 Glaucoma secondary to eye inflammation
0.666 0.334 0.000
H40.3 Glaucoma secondary to eye trauma
0.666 0.334 0.000
D32 Benign neoplasm of meninges
0.666 0.334 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.666 0.334 0.000
A46 Erysipelas
0.665 0.335 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.665 0.335 0.000
D05.9 Carcinoma in situ of breast, unspecified
0.665 0.335 0.000
J43.8 Other emphysema
0.664 0.336 0.000
J43.2 Centrilobular emphysema
0.664 0.336 0.000
J43.1 Panlobular emphysema
0.664 0.336 0.000
J43.0 MacLeod's syndrome
0.664 0.336 0.000
C18 Malignant neoplasm of colon
0.664 0.336 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.663 0.337 0.000
H52 Disorders of refraction and accommodation
0.662 0.338 0.000
T66-T78 Other and unspecified effects of external causes
0.662 0.338 0.000
N18.8 Other chronic renal failure
0.662 0.338 0.000
N18.1 Chronic kidney disease, stage 1
0.662 0.338 0.000
I45.2 Bifascicular block
0.662 0.338 0.000
N72 Inflammatory disease of cervix uteri
0.662 0.338 0.000
M10 Gout
0.661 0.338 0.000
C92 Myeloid leukaemia
0.661 0.338 0.000
E20-E35 Disorders of other endocrine glands
0.661 0.338 0.000
E11.4 With neurological complications
0.661 0.339 0.000
D17.5 Benign lipomatous neoplasm of intra-abdominal organs
0.660 0.340 0.000
A80-A89 Viral infections of the central nervous system
0.660 0.340 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.660 0.340 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.660 0.340 0.000
N15 Other renal tubulo-interstitial diseases
0.660 0.340 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.660 0.340 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.660 0.340 0.000
D31 Benign neoplasm of eye and adnexa
0.659 0.341 0.000
D30 Benign neoplasm of urinary organs
0.659 0.341 0.000
D29 Benign neoplasm of male genital organs
0.659 0.341 0.000
D28 Benign neoplasm of other and unspecified female genital organs
0.659 0.341 0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum
0.659 0.341 0.000
D19 Benign neoplasm of mesothelial tissue
0.659 0.341 0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs
0.659 0.341 0.000
C16 Malignant neoplasm of stomach
0.658 0.342 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.657 0.343 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.657 0.343 0.000
E50-E64 Other nutritional deficiencies
0.657 0.343 0.000
J94 Other pleural conditions
0.657 0.343 0.000
J91 Pleural effusion in conditions classified elsewhere
0.657 0.343 0.000
I67.2 Cerebral atherosclerosis
0.657 0.343 0.000
N76 Other inflammation of vagina and vulva
0.656 0.344 0.000
M87 Osteonecrosis
0.656 0.344 0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.656 0.344 0.000
D17.9 Benign lipomatous neoplasm, unspecified
0.655 0.345 0.000
H05 Disorders of orbit
0.655 0.345 0.000
H03 Disorders of eyelid in diseases classified elsewhere
0.655 0.345 0.000
C77.2 Intra-abdominal lymph nodes
0.655 0.345 0.000
M86 Osteomyelitis
0.654 0.346 0.000
M13.0 Polyarthritis, unspecified
0.653 0.347 0.000
D21 Other benign neoplasms of connective and other soft tissue
0.653 0.347 0.000
L84 Corns and callosities
0.653 0.347 0.000
S00-S09 Injuries to the head
0.653 0.347 0.000
M85 Other disorders of bone density and structure
0.652 0.348 0.000
D36 Benign neoplasm of other and unspecified sites
0.652 0.348 0.000
I70 Atherosclerosis
0.652 0.348 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.652 0.348 0.000
Chapter VI Diseases of the nervous system
0.652 0.348 0.000
J92.9 Pleural plaque without asbestos
0.651 0.348 0.000
M77 Other enthesopathies
0.651 0.349 0.000
H34.8 Other retinal vascular occlusions
0.650 0.350 0.000
M80 Osteoporosis with pathological fracture
0.650 0.350 0.000
Z50.0 Cardiac rehabilitation
0.650 0.350 0.000
I25 Chronic ischaemic heart disease
0.649 0.351 0.000
C21 Malignant neoplasm of anus and anal canal
0.649 0.351 0.000
E10.8 With unspecified complications
0.649 0.351 0.000
E10.7 With multiple complications
0.649 0.351 0.000
E10.6 With other specified complications
0.649 0.351 0.000
E10.5 With peripheral circulatory complications
0.649 0.351 0.000
E10.2 With renal complications
0.649 0.351 0.000
E10.0 With coma
0.649 0.351 0.000
L20-L30 Dermatitis and eczema
0.649 0.351 0.000
S89 Other and unspecified injuries of lower leg
0.649 0.351 0.000
Z50.2 Alcohol rehabilitation
0.648 0.351 0.000
J46 Status asthmaticus
0.648 0.352 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.648 0.352 0.000
N22 Calculus of urinary tract in diseases classified elsewhere
0.648 0.352 0.000
T31 Burns classified according to extent of body surface involved
0.647 0.353 0.000
E16.2 Hypoglycaemia, unspecified
0.646 0.354 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.646 0.354 0.000
M19 Other arthrosis
0.646 0.354 0.000
B99-B99 Other infectious diseases
0.644 0.355 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.644 0.355 0.000
B65-B83 Helminthiases
0.644 0.355 0.000
B50-B64 Protozoal diseases
0.644 0.355 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.644 0.355 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.644 0.355 0.000
A75-A79 Rickettsioses
0.644 0.355 0.000
A70-A74 Other diseases caused by chlamydiae
0.644 0.355 0.000
A65-A69 Other spirochaetal diseases
0.644 0.355 0.000
A20-A28 Certain zoonotic bacterial diseases
0.644 0.355 0.000
A15-A19 Tuberculosis
0.644 0.355 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.644 0.356 0.000
C56 Malignant neoplasm of ovary
0.643 0.357 0.000
H40.0 Glaucoma suspect
0.643 0.357 0.000
C90.0 Multiple myeloma
0.643 0.357 0.000
L91.0 Keloid scar
0.642 0.357 0.000
Z60.9 Problem related to social environment, unspecified
0.642 0.357 0.000
Z60.8 Other problems related to social environment
0.642 0.357 0.000
Z60.5 Target of perceived adverse discrimination and persecution
0.642 0.357 0.000
Z60.4 Social exclusion and rejection
0.642 0.357 0.000
Z60.3 Acculturation difficulty
0.642 0.357 0.000
Z60.1 Atypical parenting situation
0.642 0.357 0.000
Z60.0 Problems of adjustment to life-cycle transitions
0.642 0.357 0.000
I15.1 Hypertension secondary to other renal disorders
0.642 0.358 0.000
Z57 Occupational exposure to risk-factors
0.641 0.359 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.641 0.359 0.000
S20-S29 Injuries to the thorax
0.640 0.360 0.000
I05-I09 Chronic rheumatic heart diseases
0.640 0.360 0.000
S80.8 Other superficial injuries of lower leg
0.639 0.360 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.639 0.361 0.000
D74 Methaemoglobinaemia
0.639 0.361 0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.639 0.361 0.000
D71 Functional disorders of polymorphonuclear neutrophils
0.639 0.361 0.000
S70-S79 Injuries to the hip and thigh
0.637 0.363 0.000
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified
0.637 0.363 0.000
N13.9 Obstructive and reflux uropathy, unspecified
0.637 0.363 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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