TreeWAS – Variant ID: rs117124364

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability
Chapter VI Diseases of the nervous system	0.987	0.013
# Top node	0.981	0.019
G40-G47 Episodic and paroxysmal disorders	0.977	0.023
Chapter XX External causes of morbidity and mortality	0.976	0.024
Chapter IV Endocrine, nutritional and metabolic diseases	0.976	0.024
E10-E14 Diabetes mellitus	0.975	0.025
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.975	0.025
E14 Unspecified diabetes mellitus	0.962	0.038
G50-G59 Nerve, nerve root and plexus disorders	0.956	0.044
E14.9 Without complications	0.949	0.051
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.944	0.056
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.944	0.056
Chapter XV Pregnancy, childbirth and the puerperium	0.939	0.061
G47 Sleep disorders	0.939	0.061
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.935	0.065
E11 Non-insulin-dependent diabetes mellitus	0.934	0.066
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.923	0.077
G55 Nerve root and plexus compressions in diseases classified elsewhere	0.923	0.077
G80-G83 Cerebral palsy and other paralytic syndromes	0.903	0.097
E65-E68 Obesity and other hyperalimentation	0.901	0.099
S00-S09 Injuries to the head	0.898	0.102
O60-O75 Complications of labour and delivery	0.896	0.104
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.892	0.108
G55.1 Nerve root and plexus compressions in intervertebral disk disorders	0.892	0.108
G47.3 Sleep apnoea	0.886	0.114
G43 Migraine	0.884	0.116
S20-S29 Injuries to the thorax	0.874	0.126
M20-M25 Other joint disorders	0.873	0.127
G58 Other mononeuropathies	0.861	0.139
S01 Open wound of head	0.859	0.141
T93 Sequelae of injuries of lower limb	0.856	0.144
Y86 Sequelae of other accidents	0.856	0.144
M50-M54 Other dorsopathies	0.854	0.146
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.854	0.146
E66 Obesity	0.847	0.153
M25 Other joint disorders, not elsewhere classified	0.842	0.158
G81 Hemiplegia	0.840	0.160
E11.9 Without complications	0.836	0.164
S50-S59 Injuries to the elbow and forearm	0.834	0.166
T90 Sequelae of injuries of head	0.829	0.171
V10-V19 Pedal cyclist injured in transport accident	0.828	0.171
E66.8 Other obesity	0.827	0.173
O20-O29 Other maternal disorders predominantly related to pregnancy	0.822	0.178
G40 Epilepsy	0.821	0.179
G43.9 Migraine, unspecified	0.818	0.182
S90-S99 Injuries to the ankle and foot	0.812	0.188
M25.5 Pain in joint	0.810	0.190
S40-S49 Injuries to the shoulder and upper arm	0.809	0.191
Y41 Other systemic anti-infectives and antiparasitics	0.809	0.191
M24 Other specific joint derangements	0.807	0.193
E10 Insulin-dependent diabetes mellitus	0.804	0.196
Y52 Agents primarily affecting the cardiovascular system	0.803	0.197
E11.3 With ophthalmic complications	0.803	0.197
G41 Status epilepticus	0.802	0.198
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.797	0.203
M51 Other intervertebral disk disorders	0.797	0.203
W00-W19 Falls	0.796	0.204
G81.9 Hemiplegia, unspecified	0.795	0.205
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.793	0.207
O68 Labour and delivery complicated by foetal stress [distress]	0.777	0.223
V80-V89 Other land transport accidents	0.775	0.225
G35-G37 Demyelinating diseases of the central nervous system	0.772	0.228
T93.2 Sequelae of other fractures of lower limb	0.767	0.232
S20 Superficial injury of thorax	0.766	0.234
G54 Nerve root and plexus disorders	0.763	0.237
Y57 Other and unspecified drugs and medicaments	0.763	0.237
T92 Sequelae of injuries of upper limb	0.760	0.240
G44 Other headache syndromes	0.757	0.243
G62 Other polyneuropathies	0.757	0.243
E14.3 With ophthalmic complications	0.756	0.244
X20-X29 Contact with venomous animals and plants	0.756	0.244
S01.0 Open wound of scalp	0.756	0.244
M51.2 Other specified intervertebral disk displacement	0.755	0.245
Y85 Sequelae of transport accidents	0.752	0.248
E13 Other specified diabetes mellitus	0.752	0.248
O69 Labour and delivery complicated by umbilical cord complications	0.752	0.248
G47.0 Disorders of initiating and maintaining sleep [insomnias]	0.750	0.250
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.749	0.251
M80-M85 Disorders of bone density and structure	0.749	0.251
S10-S19 Injuries to the neck	0.749	0.251
G55.8 Nerve root and plexus compressions in other diseases classified elsewhere	0.748	0.251
G47.8 Other sleep disorders	0.747	0.252
S80-S89 Injuries to the knee and lower leg	0.744	0.256
V40-V49 Car occupant injured in transport accident	0.742	0.258
W20-W49 Exposure to inanimate mechanical forces	0.738	0.262
G63 Polyneuropathy in diseases classified elsewhere	0.737	0.263
M24.2 Disorder of ligament	0.734	0.266
G58.9 Mononeuropathy, unspecified	0.733	0.267
O94-O99 Other obstetric conditions, not elsewhere classified	0.732	0.268
G58.8 Other specified mononeuropathies	0.732	0.268
O85-O92 Complications predominantly related to the puerperium	0.731	0.269
O66 Other obstructed labour	0.730	0.270
G70-G73 Diseases of myoneural junction and muscle	0.730	0.270
T90.5 Sequelae of intracranial injury	0.729	0.271
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid	0.726	0.274
O63 Long labour	0.723	0.277
E11.5 With peripheral circulatory complications	0.723	0.277
V18 Pedal cyclist injured in noncollision transport accident	0.723	0.277
T15-T19 Effects of foreign body entering through natural orifice	0.722	0.278
M65-M68 Disorders of synovium and tendon	0.721	0.279
G40.6 Grand mal seizures, unspecified (with or without petit mal)	0.721	0.279
O26 Maternal care for other conditions predominantly related to pregnancy	0.720	0.280
T98 Sequelae of other and unspecified effects of external causes	0.718	0.281
Y41.8 Other specified systemic anti-infectives and antiparasitics	0.718	0.282
Y60-Y69 Misadventures to patients during surgical and medical care	0.718	0.282
X40-X49 Accidental poisoning by and exposure to noxious substances	0.715	0.285
E11.1 With ketoacidosis	0.715	0.285
O72 Postpartum haemorrhage	0.715	0.285
E11.4 With neurological complications	0.714	0.286
S52 Fracture of forearm	0.713	0.287
S01.8 Open wound of other parts of head	0.713	0.287
Y43 Primarily systemic agents	0.712	0.288
M60-M63 Disorders of muscles	0.712	0.288
O68.9 Labour and delivery complicated by foetal stress, unspecified	0.712	0.288
E40-E46 Malnutrition	0.708	0.291
G51 Facial nerve disorders	0.708	0.292
G00-G09 Inflammatory diseases of the central nervous system	0.707	0.293
M15-M19 Arthrosis	0.707	0.293
T66-T78 Other and unspecified effects of external causes	0.704	0.296
G47.1 Disorders of excessive somnolence [hypersomnias]	0.704	0.296
S01.9 Open wound of head, part unspecified	0.704	0.296
Chapter XVI Certain conditions originating in the perinatal period	0.703	0.296
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.703	0.297
Y88 Sequelae of surgical and medical care as external cause	0.701	0.299
G46 Vascular syndromes of brain in cerebrovascular diseases	0.700	0.300
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.700	0.300
Y35-Y36 Legal intervention and operations of war	0.700	0.300
Y10-Y34 Event of undetermined intent	0.700	0.300
Y00-Y09 Assault	0.700	0.300
X85-X99 Assault	0.700	0.300
X58-X59 Accidental exposure to other and unspecified factors	0.700	0.300
X50-X57 Overexertion, travel and privation	0.700	0.300
X30-X39 Exposure to forces of nature	0.700	0.300
X10-X19 Contact with heat and hot substances	0.700	0.300
X00-X09 Exposure to smoke, fire and flames	0.700	0.300
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.700	0.300
W75-W84 Other accidental threats to breathing	0.700	0.300
W65-W74 Accidental drowning and submersion	0.700	0.300
W50-W64 Exposure to animate mechanical forces	0.700	0.300
V98-V99 Other and unspecified transport accidents	0.700	0.300
V95-V97 Air and space transport accidents	0.700	0.300
V90-V94 Water transport accidents	0.700	0.300
V70-V79 Bus occupant injured in transport accident	0.700	0.300
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.700	0.300
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.700	0.300
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.700	0.300
V01-V09 Pedestrian injured in transport accident	0.700	0.300
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.700	0.300
E12 Malnutrition-related diabetes mellitus	0.699	0.301
Q38-Q45 Other congenital malformations of the digestive system	0.699	0.301
M25.50 Pain in joint (Multiple sites)	0.699	0.301
T33-T35 Frostbite	0.699	0.301
T26-T28 Burns and corrosions confined to eye and internal organs	0.699	0.301
T20-T25 Burns and corrosions of external body surface, specified by site	0.699	0.301
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.699	0.301
T00-T07 Injuries involving multiple body regions	0.699	0.301
M25.56 Pain in joint (Lower leg)	0.697	0.303
E50-E64 Other nutritional deficiencies	0.696	0.303
S42 Fracture of shoulder and upper arm	0.696	0.304
E10.9 Without complications	0.696	0.304
W07 Fall involving chair	0.695	0.305
M25.57 Pain in joint (Ankle and foot)	0.695	0.305
Y40 Systemic antibiotics	0.694	0.306
Y51 Drugs primarily affecting the autonomic nervous system	0.693	0.307
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.692	0.308
S99 Other and unspecified injuries of ankle and foot	0.690	0.310
M91-M94 Chondropathies	0.690	0.310
E14.8 With unspecified complications	0.689	0.310
E14.7 With multiple complications	0.689	0.310
E14.6 With other specified complications	0.689	0.310
E14.5 With peripheral circulatory complications	0.689	0.310
E14.4 With neurological complications	0.689	0.310
E14.2 Withrenal complications	0.689	0.310
E14.1 With ketoacidosis	0.689	0.310
E14.0 With coma	0.689	0.310
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.688	0.312
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.686	0.314
G61 Inflammatory polyneuropathy	0.686	0.314
G53 Cranial nerve disorders in diseases classified elsewhere	0.685	0.315
G52 Disorders of other cranial nerves	0.685	0.315
S09 Other and unspecified injuries of head	0.685	0.315
M25.7 Osteophyte	0.685	0.315
M19 Other arthrosis	0.682	0.318
T93.3 Sequelae of dislocation, sprain and strain of lower limb	0.681	0.319
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.681	0.319
Q60-Q64 Congenital malformations of the urinary system	0.681	0.319
G90-G99 Other disorders of the nervous system	0.680	0.320
S70-S79 Injuries to the hip and thigh	0.679	0.321
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures	0.678	0.322
Chapter XXII Codes for special purposes	0.678	0.322
G41.9 Status epilepticus, unspecified	0.677	0.323
T95 Sequelae of burns, corrosions and frostbite	0.677	0.323
T94 Sequelae of injuries involving multiple and unspecified body regions	0.677	0.323
T91 Sequelae of injuries of neck and trunk	0.677	0.323
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.677	0.323
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.677	0.323
M00-M03 Infectious arthropathies	0.677	0.323
M50 Cervical disk disorders	0.677	0.323
M24.0 Loose body in joint	0.676	0.324
T79-T79 Certain early complications of trauma	0.675	0.324
M21 Other acquired deformities of limbs	0.675	0.325
Q80-Q89 Other congenital malformations	0.674	0.325
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.674	0.326
S22 Fracture of rib(s), sternum and thoracic spine	0.673	0.327
G47.4 Narcolepsy and cataplexy	0.673	0.327
G47.2 Disorders of the sleep-wake schedule	0.673	0.327
V20-V29 Motorcycle rider injured in transport accident	0.673	0.327
O64 Obstructed labour due to malposition and malpresentation of foetus	0.672	0.328
O61 Failed induction of labour	0.672	0.328
Y59 Other and unspecified vaccines and biological substances	0.671	0.329
Y58 Bacterial vaccines	0.671	0.329
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.671	0.329
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.671	0.329
Y53 Agents primarily affecting the gastro-intestinal system	0.671	0.329
Y50 Central nervous system stimulants, not elsewhere classified	0.671	0.329
Y49 Psychotropic drugs, not elsewhere classified	0.671	0.329
Y48 Anaesthetics and therapeutic gases	0.671	0.329
Y47 Sedatives, hypnotics and antianxiety drugs	0.671	0.329
Y46 Antiepileptics and anti-Parkinsonism drugs	0.671	0.329
S27 Injury of other and unspecified intrathoracic organs	0.670	0.330
E11.8 With unspecified complications	0.670	0.330
E11.7 With multiple complications	0.670	0.330
E11.6 With other specified complications	0.670	0.330
E11.0 With coma	0.670	0.330
G55.2 Nerve root and plexus compressions in spondylosis	0.669	0.331
S01.5 Open wound of lip and oral cavity	0.668	0.331
G83 Other paralytic syndromes	0.667	0.333
S06 Intracranial injury	0.666	0.334
S20.2 Contusion of thorax	0.666	0.334
Y89 Sequelae of other external causes	0.662	0.338
Y87 Sequelae of intentional self-harm, assault and events of undetermined intent	0.662	0.338
G55.0 Nerve root and plexus compressions in neoplastic disease	0.662	0.338
M25.59 Pain in joint (Site unspecified)	0.661	0.339
S30 Superficial injury of abdomen, lower back and pelvis	0.659	0.341
E10.5 With peripheral circulatory complications	0.659	0.341
G50 Disorders of trigeminal nerve	0.659	0.341
S82 Fracture of lower leg, including ankle	0.657	0.343
E20-E35 Disorders of other endocrine glands	0.657	0.343
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.657	0.343
M19.0 Primary arthrosis of other joints	0.656	0.344
O73 Retained placenta and membranes, without haemorrhage	0.656	0.344
G12 Spinal muscular atrophy and related syndromes	0.654	0.346
G30-G32 Other degenerative diseases of the nervous system	0.653	0.347
M86-M90 Other osteopathies	0.653	0.347
O23 Infections of genito-urinary tract in pregnancy	0.650	0.350
M22 Disorders of patella	0.649	0.351
G80 Infantile cerebral palsy	0.646	0.354
M24.27 Disorder of ligament (Ankle and foot)	0.646	0.354
E67 Other hyperalimentation	0.646	0.354
E68 Sequelae of hyperalimentation	0.646	0.354
E65 Localised adiposity	0.646	0.354
X60-X84 Intentional self-harm	0.644	0.355
S08 Traumatic amputation of part of head	0.644	0.356
S07 Crushing injury of head	0.644	0.356
S05 Injury of eye and orbit	0.644	0.356
S04 Injury of cranial nerves	0.644	0.356
S03 Dislocation, sprain and strain of joints and ligaments of head	0.644	0.356
G47.9 Sleep disorder, unspecified	0.643	0.357
S32 Fracture of lumbar spine and pelvis	0.642	0.357
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.642	0.358
O74 Complications of anaesthesia during labour and delivery	0.642	0.358
O71 Other obstetric trauma	0.642	0.358
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified	0.642	0.358
O65 Obstructed labour due to maternal pelvic abnormality	0.642	0.358
O60 Preterm delivery	0.642	0.358
G62.9 Polyneuropathy, unspecified	0.642	0.358
E11.2 With renal complications	0.642	0.358
S01.3 Open wound of ear	0.641	0.359
G82 Paraplegia and tetraplegia	0.640	0.359
G40.8 Other epilepsy	0.640	0.360
G60 Hereditary and idiopathic neuropathy	0.640	0.360
G64 Other disorders of peripheral nervous system	0.640	0.360
Y57.9 Drug or medicament, unspecified	0.639	0.361
M84 Disorders of continuity of bone	0.639	0.361
G59 Mononeuropathy in diseases classified elsewhere	0.638	0.362
T90.4 Sequelae of injury of eye and orbit	0.638	0.362
O69.2 Labour and delivery complicated by other cord entanglement	0.637	0.363
S51 Open wound of forearm	0.636	0.364
G43.8 Other migraine	0.634	0.366
G43.3 Complicated migraine	0.634	0.366
G43.2 Status migrainosus	0.634	0.366
G43.1 Migraine with aura [classical migraine]	0.634	0.366
G43.0 Migraine without aura [common migraine]	0.634	0.366
G55.3 Nerve root and plexus compressions in other dorsopathies	0.632	0.368
V89 Motor- or nonmotor-vehicle accident, type of vehicle unspecified	0.631	0.369
M25.53 Pain in joint (Forearm)	0.631	0.369
M25.51 Pain in joint (Shoulder region)	0.630	0.370
Y85.0 Sequelae of motor-vehicle accident	0.629	0.371
O62 Abnormalities of forces of labour	0.629	0.371
M05-M14 Inflammatory polyarthropathies	0.629	0.371
S29 Other and unspecified injuries of thorax	0.627	0.373
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.627	0.373
S26 Injury of heart	0.627	0.373
S25 Injury of blood vessels of thorax	0.627	0.373
S24 Injury of nerves and spinal cord at thorax level	0.627	0.373
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.627	0.373
S21 Open wound of thorax	0.627	0.373
G63.2 Diabetic polyneuropathy	0.626	0.374
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.626	0.374
M33 Dermatopolymyositis	0.626	0.374
M32 Systemic lupus erythematosus	0.626	0.374
M30 Polyarteritis nodosa and related conditions	0.626	0.374
O75 Other complications of labour and delivery, not elsewhere classified	0.624	0.376
S46 Injury of muscle and tendon at shoulder and upper arm level	0.624	0.376
M25.8 Other specified joint disorders	0.623	0.377
S01.2 Open wound of nose	0.621	0.379
G40.3 Generalised idiopathic epilepsy and epileptic syndromes	0.620	0.380
Y43.4 Immunosuppressive agents	0.619	0.381
G20-G26 Extrapyramidal and movement disorders	0.619	0.381
M34 Systemic sclerosis	0.618	0.382
G58.7 Mononeuritis multiplex	0.617	0.383
G58.0 Intercostal neuropathy	0.617	0.383
O26.9 Pregnancy-related condition, unspecified	0.616	0.384
S01.7 Multiple open wounds of head	0.616	0.384
S01.4 Open wound of cheek and temporomandibular area	0.616	0.384
O66.0 Obstructed labour due to shoulder dystocia	0.615	0.384
M96 Postprocedural musculoskeletal disorders, not elsewhere classified	0.615	0.385
S01.1 Open wound of eyelid and periocular area	0.614	0.386
T93.9 Sequelae of unspecified injury of lower limb	0.613	0.386
T93.8 Sequelae of other specified injuries of lower limb	0.613	0.386
T93.6 Sequelae of crushing injury and traumatic amputation of lower limb	0.613	0.386
T93.5 Sequelae of injury of muscle and tendon of lower limb	0.613	0.386
T93.4 Sequelae of injury of nerve of lower limb	0.613	0.386
T93.1 Sequelae of fracture of femur	0.613	0.386
T93.0 Sequelae of open wound of lower limb	0.613	0.386
M24.24 Disorder of ligament (Hand)	0.613	0.387
S92 Fracture of foot, except ankle	0.613	0.387
M53 Other dorsopathies, not elsewhere classified	0.612	0.387
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.612	0.387
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.612	0.387
Q50-Q56 Congenital malformations of genital organs	0.612	0.387
Q35-Q37 Cleft lip and cleft palate	0.612	0.387
Q30-Q34 Congenital malformations of the respiratory system	0.612	0.387
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.612	0.387
M40-M43 Deforming dorsopathies	0.611	0.389
W07.0 Home	0.610	0.389
M85 Other disorders of bone density and structure	0.610	0.390
T92.1 Sequelae of fracture of arm	0.610	0.390
G37 Other demyelinating diseases of central nervous system	0.609	0.391
M25.54 Pain in joint (Hand)	0.608	0.392
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.607	0.393
E66.2 Extreme obesity with alveolar hypoventilation	0.607	0.393
E66.1 Drug-induced obesity	0.607	0.393
E66.0 Obesity due to excess calories	0.607	0.393
V18.0 Driver injured in nontraffic accident	0.607	0.393
O21 Excessive vomiting in pregnancy	0.606	0.394
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.606	0.394
W29 Contact with other powered hand tools and household machinery	0.606	0.394
Y44 Agents primarily affecting blood constituents	0.604	0.396
M25.9 Joint disorder, unspecified	0.603	0.397
M25.6 Stiffness of joint, not elsewhere classified	0.603	0.397
M25.3 Other instability of joint	0.603	0.397
M25.2 Flail joint	0.603	0.397
M25.1 Fistula of joint	0.603	0.397
M25.0 Haemarthrosis	0.603	0.397
S99.9 Unspecified injury of ankle and foot	0.603	0.397
G81.1 Spastic hemiplegia	0.602	0.398
G81.0 Flaccid hemiplegia	0.602	0.398
M51.0 Lumbar and other intervertebral disk disorders with myelopathy	0.602	0.398
Q00-Q07 Congenital malformations of the nervous system	0.601	0.399
M70-M79 Other soft tissue disorders	0.601	0.399
Q20-Q28 Congenital malformations of the circulatory system	0.600	0.400
G54.0 Brachial plexus disorders	0.598	0.402
O63.1 Prolonged second stage (of labour)	0.598	0.402
X23 Contact with hornets, wasps and bees	0.598	0.402
T90.9 Sequelae of unspecified injury of head	0.598	0.402
S59 Other and unspecified injuries of forearm	0.598	0.402
S58 Traumatic amputation of forearm	0.598	0.402
S57 Crushing injury of forearm	0.598	0.402
S56 Injury of muscle and tendon at forearm level	0.598	0.402
S55 Injury of blood vessels at forearm level	0.598	0.402
S54 Injury of nerves at forearm level	0.598	0.402
S53 Dislocation, sprain and strain of joints and ligaments of elbow	0.598	0.402
T92.9 Sequelae of unspecified injury of upper limb	0.597	0.402
S50 Superficial injury of forearm	0.597	0.402
S20.8 Superficial injuries of other and unspecified parts of thorax	0.596	0.404
T90.8 Sequelae of other specified injuries of head	0.594	0.406
T90.3 Sequelae of injury of cranial nerves	0.594	0.406
T90.1 Sequelae of open wound of head	0.594	0.406
T90.0 Sequelae of superficial injury of head	0.594	0.406
V19 Pedal cyclist injured in other and unspecified transport accidents	0.594	0.406
V17 Pedal cyclist injured in collision with fixed or stationary object	0.594	0.406
V16 Pedal cyclist injured in collision with other nonmotor vehicle	0.594	0.406
V15 Pedal cyclist injured in collision with railway train or railway vehicle	0.594	0.406
V14 Pedal cyclist injured in collision with heavy transport vehicle or bus	0.594	0.406
V13 Pedal cyclist injured in collision with car, pick-up truck or van	0.594	0.406
V12 Pedal cyclist injured in collision with two- or three-wheeled motor vehicle	0.594	0.406
V11 Pedal cyclist injured in collision with other pedal cycle	0.594	0.406
V10 Pedal cyclist injured in collision with pedestrian or animal	0.594	0.406
E13.9 Without complications	0.591	0.409
O29 Complications of anaesthesia during pregnancy	0.590	0.410
O28 Abnormal findings on antenatal screening of mother	0.590	0.410
O24 Diabetes mellitus in pregnancy	0.590	0.410
O22 Venous complications in pregnancy	0.590	0.410
O25 Malnutrition in pregnancy	0.590	0.410
V18.2 Unspecified pedal cyclist injured in nontraffic accident	0.589	0.411
G40.7 Petit mal, unspecified, without grand mal seizures	0.589	0.411
G40.5 Special epileptic syndromes	0.589	0.411
G40.4 Other generalised epilepsy and epileptic syndromes	0.589	0.411
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures	0.589	0.411
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset	0.589	0.411
M19.01 Primary arthrosis of other joints (Shoulder region)	0.588	0.412
S52.6 Fracture of lower end of both ulna and radius	0.587	0.412
M23 Internal derangement of knee	0.586	0.414
T90.2 Sequelae of fracture of skull and facial bones	0.586	0.414
M50.1 Cervical disk disorder with radiculopathy	0.585	0.415
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.585	0.415
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.584	0.416
M65 Synovitis and tenosynovitis	0.583	0.416
M24.07 Loose body in joint (Ankle and foot)	0.583	0.417
O86 Other puerperal infections	0.582	0.418
S98 Traumatic amputation of ankle and foot	0.582	0.418
S97 Crushing injury of ankle and foot	0.582	0.418
S96 Injury of muscle and tendon at ankle and foot level	0.582	0.418
S95 Injury of blood vessels at ankle and foot level	0.582	0.418
S94 Injury of nerves at ankle and foot level	0.582	0.418
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.582	0.418
G54.9 Nerve root and plexus disorder, unspecified	0.582	0.418
S90 Superficial injury of ankle and foot	0.581	0.419
M25.58 Pain in joint (Other)	0.581	0.419
M25.52 Pain in joint (Upper arm)	0.581	0.419
M31 Other necrotising vasculopathies	0.581	0.419
M25.77 Osteophyte (Ankle and foot)	0.580	0.420
S49 Other and unspecified injuries of shoulder and upper arm	0.580	0.420
S48 Traumatic amputation of shoulder and upper arm	0.580	0.420
S45 Injury of blood vessels at shoulder and upper arm level	0.580	0.420
S44 Injury of nerves at shoulder and upper arm level	0.580	0.420
S41 Open wound of shoulder and upper arm	0.580	0.420
S40 Superficial injury of shoulder and upper arm	0.580	0.420
S47 Crushing injury of shoulder and upper arm	0.580	0.420
Y41.9 Systemic anti-infective and antiparasitic, unspecified	0.580	0.420
Y41.5 Antiviral drugs	0.580	0.420
Y41.4 Anthelminthics	0.580	0.420
Y41.3 Other antiprotozoal drugs	0.580	0.420
Y41.2 Antimalarials and drugs acting on other blood protozoa	0.580	0.420
Y41.1 Antimycobacterial drugs	0.580	0.420
Y41.0 Sulphonamides	0.580	0.420
M24.9 Joint derangement, unspecified	0.579	0.421
M24.8 Other specific joint derangements, not elsewhere classified	0.579	0.421
M24.7 Protrusio acetabuli	0.579	0.421
M24.6 Ankylosis of joint	0.579	0.421
M24.5 Contracture of joint	0.579	0.421
M24.4 Recurrent dislocation and subluxation of joint	0.579	0.421
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.579	0.421
M25.78 Osteophyte (Other)	0.579	0.421
G44.0 Cluster headache syndrome	0.578	0.422
G62.8 Other specified polyneuropathies	0.577	0.422
E10.8 With unspecified complications	0.576	0.424
E10.7 With multiple complications	0.576	0.424
E10.6 With other specified complications	0.576	0.424
E10.4 With neurological complications	0.576	0.424
E10.2 With renal complications	0.576	0.424
E10.0 With coma	0.576	0.424
O26.8 Other specified pregnancy-related conditions	0.576	0.424
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system	0.576	0.424
Y52.8 Antivaricose drugs, including sclerosing agents	0.576	0.424
Y52.7 Peripheral vasodilators	0.576	0.424
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.576	0.424
Y52.4 Angiotensin-converting-enzyme inhibitors	0.576	0.424
Y52.1 Calcium-channel blockers	0.576	0.424
Y52.0 Cardiac-stimulant glycosides and drugs of similar action	0.576	0.424
G41.8 Other status epilepticus	0.575	0.425
G41.2 Complex partial status epilepticus	0.575	0.425
G41.1 Petit mal status epilepticus	0.575	0.425
G41.0 Grand mal status epilepticus	0.575	0.425
V49 Car occupant injured in other and unspecified transport accidents	0.574	0.426
Q39 Congenital malformations of oesophagus	0.573	0.427
S82.5 Fracture of medial malleolus	0.573	0.427
M19.07 Primary arthrosis of other joints (Ankle and foot)	0.573	0.427
W06 Fall involving bed	0.572	0.428
O34 Maternal care for known or suspected abnormality of pelvic organs	0.572	0.428
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.572	0.428
S37 Injury of urinary and pelvic organs	0.572	0.428
S36 Injury of intra-abdominal organs	0.572	0.428
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.572	0.428
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.572	0.428
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.572	0.428
S31 Open wound of abdomen, lower back and pelvis	0.572	0.428
M51.3 Other specified intervertebral disk degeneration	0.571	0.429
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy	0.571	0.429
M51.9 Intervertebral disk disorder, unspecified	0.571	0.429
M51.4 Schmorl's nodes	0.571	0.429
W18 Other fall on same level	0.571	0.429
W17 Other fall from one level to another	0.571	0.429
W16 Diving or jumping into water causing injury other than drowning or submersion	0.571	0.429
W15 Fall from cliff	0.571	0.429
W14 Fall from tree	0.571	0.429
W12 Fall on and from scaffolding	0.571	0.429
W11 Fall on and from ladder	0.571	0.429
W10 Fall on and from stairs and steps	0.571	0.429
W09 Fall involving playground equipment	0.571	0.429
W08 Fall involving other furniture	0.571	0.429
W05 Fall involving wheelchair	0.571	0.429
W04 Fall while being carried or supported by other persons	0.571	0.429
W03 Other fall on same level due to collision with, or pushing by, another person	0.571	0.429
W02 Fall involving ice-skates, skis, roller-skates or skateboards	0.571	0.429
W01 Fall on same level from slipping, tripping and stumbling	0.571	0.429
W00 Fall on same level involving ice and snow	0.571	0.429
S42.3 Fracture of shaft of humerus	0.570	0.430
S52.1 Fracture of upper end of radius	0.570	0.430

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations