TreeWAS – Variant ID: rs117161928

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability
# Top node	1.000	0.000
Chapter V Mental and behavioural disorders	0.999	0.001
Chapter I Certain infectious and parasitic diseases	0.997	0.003
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.996	0.004
F30-F39 Mood [affective] disorders	0.993	0.007
F32 Depressive episode	0.983	0.017
Chapter XX External causes of morbidity and mortality	0.982	0.018
Chapter II Neoplasms	0.970	0.030
F32.9 Depressive episode, unspecified	0.968	0.032
B95-B98 Bacterial, viral and other infectious agents	0.967	0.033
Chapter IV Endocrine, nutritional and metabolic diseases	0.966	0.034
B96 Other bacterial agents as the cause of diseases classified to other chapters	0.955	0.045
A00-A09 Intestinal infectious diseases	0.952	0.048
Chapter X Diseases of the respiratory system	0.946	0.054
Chapter XIV Diseases of the genitourinary system	0.939	0.061
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters	0.937	0.063
N17-N19 Renal failure	0.918	0.082
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.917	0.083
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.912	0.088
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.910	0.090
N17 Acute renal failure	0.902	0.098
N70-N77 Inflammatory diseases of female pelvic organs	0.899	0.101
S00-S09 Injuries to the head	0.894	0.106
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.890	0.110
N17.9 Acute renal failure, unspecified	0.890	0.110
F00-F09 Organic, including symptomatic, mental disorders	0.888	0.112
E16 Other disorders of pancreatic internal secretion	0.883	0.117
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters	0.881	0.119
J90-J94 Other diseases of pleura	0.880	0.119
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.873	0.127
E40-E46 Malnutrition	0.871	0.129
A09 Diarrhoea and gastro-enteritis of presumed infectious origin	0.864	0.136
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.859	0.140
E16.2 Hypoglycaemia, unspecified	0.858	0.142
S80-S89 Injuries to the knee and lower leg	0.849	0.151
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.848	0.152
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.846	0.154
J30-J39 Other diseases of upper respiratory tract	0.846	0.154
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.845	0.155
D37-D48 Neoplasms of uncertain or unknown behaviour	0.843	0.157
J90 Pleural effusion, not elsewhere classified	0.842	0.158
S90-S99 Injuries to the ankle and foot	0.841	0.159
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.841	0.159
S60-S69 Injuries to the wrist and hand	0.834	0.166
E10-E14 Diabetes mellitus	0.831	0.169
F33 Recurrent depressive disorder	0.829	0.171
S40-S49 Injuries to the shoulder and upper arm	0.825	0.175
F99-F99 Unspecified mental disorder	0.821	0.179
T79-T79 Certain early complications of trauma	0.820	0.180
F32.1 Moderate depressive episode	0.819	0.181
Y86 Sequelae of other accidents	0.810	0.190
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.805	0.195
W00-W19 Falls	0.805	0.195
E46 Unspecified protein-energy malnutrition	0.803	0.197
F05 Delirium, not induced by alcohol and other psychoactive substances	0.803	0.197
F32.0 Mild depressive episode	0.803	0.197
S01 Open wound of head	0.799	0.201
A09.9 Gastroenteritis and colitis of unspecified origin	0.798	0.202
A08 Viral and other specified intestinal infections	0.798	0.202
Y95 Nosocomial condition	0.795	0.205
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.790	0.210
J32 Chronic sinusitis	0.790	0.210
A30-A49 Other bacterial diseases	0.790	0.210
F20 Schizophrenia	0.788	0.212
C43-C44 Melanoma and other malignant neoplasms of skin	0.787	0.213
D00-D09 In situ neoplasms	0.787	0.213
A04 Other bacterial intestinal infections	0.782	0.218
W20-W49 Exposure to inanimate mechanical forces	0.782	0.218
N19 Unspecified renal failure	0.781	0.219
M05-M14 Inflammatory polyarthropathies	0.777	0.223
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.775	0.225
D70-D77 Other diseases of blood and blood-forming organs	0.775	0.225
N73 Other female pelvic inflammatory diseases	0.774	0.226
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters	0.773	0.227
N72 Inflammatory disease of cervix uteri	0.772	0.228
Chapter XXII Codes for special purposes	0.771	0.229
C15-C26 Malignant neoplasms of digestive organs	0.770	0.230
Y43 Primarily systemic agents	0.770	0.230
F31 Bipolar affective disorder	0.767	0.233
S10-S19 Injuries to the neck	0.767	0.233
C51-C58 Malignant neoplasms of female genital organs	0.767	0.233
F25 Schizoaffective disorders	0.765	0.235
J09-J18 Influenza and pneumonia	0.763	0.237
F32.3 Severe depressive episode with psychotic symptoms	0.756	0.244
B97 Viral agents as the cause of diseases classified to other chapters	0.754	0.246
N30-N39 Other diseases of urinary system	0.753	0.247
S61 Open wound of wrist and hand	0.752	0.248
S20-S29 Injuries to the thorax	0.749	0.251
C77 Secondary and unspecified malignant neoplasm of lymph nodes	0.749	0.251
Chapter VIII Diseases of the ear and mastoid process	0.748	0.252
X20-X29 Contact with venomous animals and plants	0.748	0.252
N76 Other inflammation of vagina and vulva	0.747	0.253
J32.9 Chronic sinusitis, unspecified	0.747	0.253
S02 Fracture of skull and facial bones	0.747	0.253
Chapter VII Diseases of the eye and adnexa	0.746	0.254
B15-B19 Viral hepatitis	0.745	0.255
Y85 Sequelae of transport accidents	0.744	0.256
M65-M68 Disorders of synovium and tendon	0.743	0.257
F05.9 Delirium, unspecified	0.742	0.258
V20-V29 Motorcycle rider injured in transport accident	0.739	0.261
S91 Open wound of ankle and foot	0.739	0.261
N75 Diseases of Bartholin's gland	0.735	0.265
T15-T19 Effects of foreign body entering through natural orifice	0.735	0.265
S06 Intracranial injury	0.733	0.267
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.733	0.267
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.732	0.267
N39 Other disorders of urinary system	0.732	0.268
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.731	0.269
J80-J84 Other respiratory diseases principally affecting the interstitium	0.730	0.270
E20-E35 Disorders of other endocrine glands	0.729	0.271
N99-N99 Other disorders of the genitourinary system	0.727	0.273
C80 Malignant neoplasm without specification of site	0.727	0.273
M06 Other rheumatoid arthritis	0.727	0.273
J34 Other disorders of nose and nasal sinuses	0.727	0.273
S61.8 Open wound of other parts of wrist and hand	0.721	0.279
B25-B34 Other viral diseases	0.719	0.281
Y88 Sequelae of surgical and medical care as external cause	0.718	0.281
J00-J06 Acute upper respiratory infections	0.718	0.282
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.716	0.284
F80-F89 Disorders of psychological development	0.716	0.284
F70-F79 Mental retardation	0.716	0.284
F60-F69 Disorders of adult personality and behaviour	0.716	0.284
B99-B99 Other infectious diseases	0.715	0.285
B90-B94 Sequelae of infectious and parasitic diseases	0.715	0.285
B85-B89 Pediculosis, acariasis and other infestations	0.715	0.285
B65-B83 Helminthiases	0.715	0.285
B50-B64 Protozoal diseases	0.715	0.285
B20-B24 Human immunodeficiency virus [HIV] disease	0.715	0.285
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.715	0.285
A80-A89 Viral infections of the central nervous system	0.715	0.285
A75-A79 Rickettsioses	0.715	0.285
A70-A74 Other diseases caused by chlamydiae	0.715	0.285
A65-A69 Other spirochaetal diseases	0.715	0.285
A20-A28 Certain zoonotic bacterial diseases	0.715	0.285
A15-A19 Tuberculosis	0.715	0.285
T33-T35 Frostbite	0.714	0.286
T26-T28 Burns and corrosions confined to eye and internal organs	0.714	0.286
T20-T25 Burns and corrosions of external body surface, specified by site	0.714	0.286
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.714	0.286
T00-T07 Injuries involving multiple body regions	0.714	0.286
A50-A64 Infections with a predominantly sexual mode of transmission	0.713	0.287
F33.9 Recurrent depressive disorder, unspecified	0.712	0.288
F38 Other mood [affective] disorders	0.712	0.288
F34 Persistent mood [affective] disorders	0.712	0.288
F30 Manic episode	0.712	0.288
F39 Unspecified mood [affective] disorder	0.712	0.288
B35-B49 Mycoses	0.711	0.289
C16 Malignant neoplasm of stomach	0.710	0.290
X60-X84 Intentional self-harm	0.710	0.290
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.710	0.290
M45-M49 Spondylopathies	0.710	0.290
J33 Nasal polyp	0.709	0.291
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.708	0.292
F32.8 Other depressive episodes	0.705	0.295
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.704	0.296
Y35-Y36 Legal intervention and operations of war	0.704	0.296
Y10-Y34 Event of undetermined intent	0.704	0.296
Y00-Y09 Assault	0.704	0.296
X85-X99 Assault	0.704	0.296
X58-X59 Accidental exposure to other and unspecified factors	0.704	0.296
X50-X57 Overexertion, travel and privation	0.704	0.296
X40-X49 Accidental poisoning by and exposure to noxious substances	0.704	0.296
X30-X39 Exposure to forces of nature	0.704	0.296
X10-X19 Contact with heat and hot substances	0.704	0.296
X00-X09 Exposure to smoke, fire and flames	0.704	0.296
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.704	0.296
W75-W84 Other accidental threats to breathing	0.704	0.296
W65-W74 Accidental drowning and submersion	0.704	0.296
W50-W64 Exposure to animate mechanical forces	0.704	0.296
V98-V99 Other and unspecified transport accidents	0.704	0.296
V95-V97 Air and space transport accidents	0.704	0.296
V90-V94 Water transport accidents	0.704	0.296
V80-V89 Other land transport accidents	0.704	0.296
V70-V79 Bus occupant injured in transport accident	0.704	0.296
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.704	0.296
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.704	0.296
V40-V49 Car occupant injured in transport accident	0.704	0.296
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.704	0.296
V01-V09 Pedestrian injured in transport accident	0.704	0.296
S70-S79 Injuries to the hip and thigh	0.704	0.296
T93 Sequelae of injuries of lower limb	0.703	0.297
J60-J70 Lung diseases due to external agents	0.703	0.297
B02 Zoster [herpes zoster]	0.703	0.297
Y43.3 Other antineoplastic drugs	0.702	0.298
F20.9 Schizophrenia, unspecified	0.702	0.298
V10-V19 Pedal cyclist injured in transport accident	0.702	0.298
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.701	0.299
N80-N98 Noninflammatory disorders of female genital tract	0.701	0.299
S42 Fracture of shoulder and upper arm	0.701	0.299
E11 Non-insulin-dependent diabetes mellitus	0.697	0.303
J95-J99 Other diseases of the respiratory system	0.695	0.305
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.695	0.305
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.695	0.305
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.695	0.305
C40-C41 Malignant neoplasms of bone and articular cartilage	0.695	0.305
T79 Certain early complications of trauma, not elsewhere classified	0.695	0.305
N80 Endometriosis	0.695	0.305
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.694	0.306
F99 Mental disorder, not otherwise specified	0.694	0.306
D45 Polycythaemia vera	0.691	0.309
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.688	0.312
N80.0 Endometriosis of uterus	0.688	0.312
A08.4 Viral intestinal infection, unspecified	0.687	0.313
D70 Agranulocytosis	0.687	0.313
Chapter IX Diseases of the circulatory system	0.686	0.314
N73.6 Female pelvic peritoneal adhesions	0.685	0.315
N88 Other noninflammatory disorders of cervix uteri	0.685	0.315
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters	0.684	0.315
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters	0.684	0.315
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters	0.684	0.315
B96.0 Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified to other chapters	0.684	0.315
A07 Other protozoal intestinal diseases	0.683	0.317
A06 Amoebiasis	0.683	0.317
A05 Other bacterial foodborne intoxications	0.683	0.317
A03 Shigellosis	0.683	0.317
A02 Other Salmonella infections	0.683	0.317
A01 Typhoid and paratyphoid fevers	0.683	0.317
A00 Cholera	0.683	0.317
S50-S59 Injuries to the elbow and forearm	0.682	0.318
C83 Diffuse non-Hodgkin's lymphoma	0.680	0.320
C77.3 Axillary and upper limb lymph nodes	0.680	0.320
M06.9 Rheumatoid arthritis, unspecified	0.680	0.320
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.676	0.324
T66-T78 Other and unspecified effects of external causes	0.675	0.325
C79 Secondary malignant neoplasm of other sites	0.675	0.325
C90 Multiple myeloma and malignant plasma cell neoplasms	0.674	0.326
T90 Sequelae of injuries of head	0.672	0.328
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters	0.671	0.329
F29 Unspecified nonorganic psychosis	0.670	0.330
S80 Superficial injury of lower leg	0.669	0.331
S01.5 Open wound of lip and oral cavity	0.668	0.332
S89 Other and unspecified injuries of lower leg	0.667	0.333
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.667	0.333
S01.9 Open wound of head, part unspecified	0.666	0.334
S91.3 Open wound of other parts of foot	0.665	0.335
W44 Foreign body entering into or through eye or natural orifice	0.665	0.335
E10 Insulin-dependent diabetes mellitus	0.664	0.336
H55-H59 Other disorders of eye and adnexa	0.664	0.336
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.663	0.337
T91 Sequelae of injuries of neck and trunk	0.662	0.338
A04.5 Campylobacter enteritis	0.662	0.338
F03 Unspecified dementia	0.661	0.338
F25.9 Schizoaffective disorder, unspecified	0.661	0.339
W17 Other fall from one level to another	0.658	0.341
E15 Nondiabetic hypoglycaemic coma	0.658	0.342
J93 Pneumothorax	0.657	0.343
H53-H54 Visual disturbances and blindness	0.657	0.343
M67 Other disorders of synovium and tendon	0.656	0.344
F22 Persistent delusional disorders	0.656	0.344
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.654	0.345
Y89 Sequelae of other external causes	0.654	0.346
Y87 Sequelae of intentional self-harm, assault and events of undetermined intent	0.654	0.346
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.653	0.347
F23 Acute and transient psychotic disorders	0.652	0.347
F28 Other nonorganic psychotic disorders	0.652	0.347
F24 Induced delusional disorder	0.652	0.347
F21 Schizotypal disorder	0.652	0.347
T36-T50 Poisoning by drugs, medicaments and biological substances	0.651	0.349
N94 Pain and other conditions associated with female genital organs and menstrual cycle	0.651	0.349
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.650	0.350
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.649	0.351
N88.2 Stricture and stenosis of cervix uteri	0.648	0.352
N17.8 Other acute renal failure	0.646	0.354
N17.2 Acute renal failure with medullary necrosis	0.646	0.354
N17.1 Acute renal failure with acute cortical necrosis	0.646	0.354
N17.0 Acute renal failure with tubular necrosis	0.646	0.354
J33.0 Polyp of nasal cavity	0.646	0.354
H65-H75 Diseases of middle ear and mastoid	0.645	0.355
N77 Vulvovaginal ulceration and inflammation in diseases classified elsewhere	0.644	0.356
N74 Female pelvic inflammatory disorders in diseases classified elsewhere	0.644	0.356
N71 Inflammatory disease of uterus, except cervix	0.644	0.356
W10 Fall on and from stairs and steps	0.642	0.358
Y52 Agents primarily affecting the cardiovascular system	0.642	0.358
S08 Traumatic amputation of part of head	0.641	0.359
S07 Crushing injury of head	0.641	0.359
S05 Injury of eye and orbit	0.641	0.359
S04 Injury of cranial nerves	0.641	0.359
S03 Dislocation, sprain and strain of joints and ligaments of head	0.641	0.359
Y60-Y69 Misadventures to patients during surgical and medical care	0.638	0.361
C76 Malignant neoplasm of other and ill-defined sites	0.638	0.361
F00 Dementia in Alzheimer's disease	0.638	0.362
J36 Peritonsillar abscess	0.637	0.363
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction	0.637	0.363
F06 Other mental disorders due to brain damage and dysfunction and to physical disease	0.637	0.363
F02 Dementia in other diseases classified elsewhere	0.637	0.363
F09 Unspecified organic or symptomatic mental disorder	0.637	0.363
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances	0.637	0.363
A04.8 Other specified bacterial intestinal infections	0.637	0.363
T85 Complications of other internal prosthetic devices, implants and grafts	0.636	0.364
C50-C50 Malignant neoplasm of breast	0.635	0.365
C54 Malignant neoplasm of corpus uteri	0.635	0.365
C34 Malignant neoplasm of bronchus and lung	0.635	0.365
S02.5 Fracture of tooth	0.634	0.366
D04 Carcinoma in situ of skin	0.634	0.366
S01.1 Open wound of eyelid and periocular area	0.633	0.367
E16.9 Disorder of pancreatic internal secretion, unspecified	0.633	0.367
E16.8 Other specified disorders of pancreatic internal secretion	0.633	0.367
E16.4 Abnormal secretion of gastrin	0.633	0.367
E16.3 Increased secretion of glucagon	0.633	0.367
E16.1 Other hypoglycaemia	0.633	0.367
E16.0 Drug-induced hypoglycaemia without coma	0.633	0.367
C43 Malignant melanoma of skin	0.632	0.368
C81 Hodgkin's disease	0.632	0.368
J94 Other pleural conditions	0.631	0.369
J91 Pleural effusion in conditions classified elsewhere	0.631	0.369
F01 Vascular dementia	0.631	0.369
N25-N29 Other disorders of kidney and ureter	0.630	0.370
S40 Superficial injury of shoulder and upper arm	0.629	0.371
B02.9 Zoster without complication	0.629	0.371
A09.0 Other and unspecified gastroenteritis and colitis of infectious origin	0.629	0.371
Q60-Q64 Congenital malformations of the urinary system	0.627	0.373
Y91 Evidence of alcohol involvement determined by level of intoxication	0.626	0.374
Y90 Evidence of alcohol involvement determined by blood alcohol level	0.626	0.374
Y98 Lifestyle-related condition	0.626	0.374
Y97 Environmental-pollution-related condition	0.626	0.374
Y96 Work-related condition	0.626	0.374
C80.9 Malignant neoplasm, unspecified	0.626	0.374
E44 Protein-energy malnutrition of moderate and mild degree	0.625	0.375
E45 Retarded development following protein-energy malnutrition	0.625	0.375
E43 Unspecified severe protein-energy malnutrition	0.625	0.375
E42 Marasmic kwashiorkor	0.625	0.375
E41 Nutritional marasmus	0.625	0.375
E40 Kwashiorkor	0.625	0.375
E50-E64 Other nutritional deficiencies	0.624	0.376
M91-M94 Chondropathies	0.624	0.376
E65-E68 Obesity and other hyperalimentation	0.623	0.377
C16.0 Cardia	0.623	0.377
F40-F48 Neurotic, stress-related and somatoform disorders	0.623	0.377
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.622	0.378
D73 Diseases of spleen	0.622	0.378
N39.4 Other specified urinary incontinence	0.621	0.379
E00-E07 Disorders of thyroid gland	0.621	0.379
N39.8 Other specified disorders of urinary system	0.620	0.380
S01.4 Open wound of cheek and temporomandibular area	0.620	0.380
N39.9 Disorder of urinary system, unspecified	0.619	0.381
D80-D89 Certain disorders involving the immune mechanism	0.619	0.381
A41 Other septicaemia	0.619	0.381
D06 Carcinoma in situ of cervix uteri	0.618	0.382
J34.2 Deviated nasal septum	0.618	0.382
E11.4 With neurological complications	0.618	0.382
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.618	0.382
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.617	0.383
H46-H48 Disorders of optic nerve and visual pathways	0.617	0.383
T98 Sequelae of other and unspecified effects of external causes	0.616	0.384
T95 Sequelae of burns, corrosions and frostbite	0.616	0.384
T94 Sequelae of injuries involving multiple and unspecified body regions	0.616	0.384
T92 Sequelae of injuries of upper limb	0.616	0.384
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.616	0.384
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.616	0.384
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.615	0.385
M10 Gout	0.614	0.386
C16.9 Stomach, unspecified	0.613	0.387
S81 Open wound of lower leg	0.612	0.388
Y51 Drugs primarily affecting the autonomic nervous system	0.609	0.391
S88 Traumatic amputation of lower leg	0.608	0.391
S87 Crushing injury of lower leg	0.608	0.391
S86 Injury of muscle and tendon at lower leg level	0.608	0.391
S85 Injury of blood vessels at lower leg level	0.608	0.391
S84 Injury of nerves at lower leg level	0.608	0.391
M60-M63 Disorders of muscles	0.608	0.392
M00-M03 Infectious arthropathies	0.608	0.392
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.607	0.393
C15 Malignant neoplasm of oesophagus	0.607	0.393
F32.2 Severe depressive episode without psychotic symptoms	0.606	0.393
Y59 Other and unspecified vaccines and biological substances	0.606	0.393
Y58 Bacterial vaccines	0.606	0.393
Y57 Other and unspecified drugs and medicaments	0.606	0.393
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.606	0.393
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.606	0.393
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.606	0.393
Y53 Agents primarily affecting the gastro-intestinal system	0.606	0.393
Y50 Central nervous system stimulants, not elsewhere classified	0.606	0.393
Y49 Psychotropic drugs, not elsewhere classified	0.606	0.393
Y48 Anaesthetics and therapeutic gases	0.606	0.393
Y47 Sedatives, hypnotics and antianxiety drugs	0.606	0.393
Y46 Antiepileptics and anti-Parkinsonism drugs	0.606	0.393
Y44 Agents primarily affecting blood constituents	0.606	0.393
Y41 Other systemic anti-infectives and antiparasitics	0.606	0.393
J37 Chronic laryngitis and laryngotracheitis	0.606	0.394
D55-D59 Haemolytic anaemias	0.606	0.394
J13 Pneumonia due to Streptococcus pneumoniae	0.606	0.394
N39.0 Urinary tract infection, site not specified	0.606	0.394
M47 Spondylosis	0.606	0.394
S69 Other and unspecified injuries of wrist and hand	0.605	0.395
T79.3 Post-traumatic wound infection, not elsewhere classified	0.605	0.395
I95-I99 Other and unspecified disorders of the circulatory system	0.605	0.395
D46 Myelodysplastic syndromes	0.604	0.395
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.604	0.395
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.604	0.395
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.604	0.395
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.604	0.395
A46 Erysipelas	0.604	0.396
J11 Influenza, virus not identified	0.604	0.396
S99 Other and unspecified injuries of ankle and foot	0.603	0.397
S98 Traumatic amputation of ankle and foot	0.603	0.397
S97 Crushing injury of ankle and foot	0.603	0.397
S96 Injury of muscle and tendon at ankle and foot level	0.603	0.397
S95 Injury of blood vessels at ankle and foot level	0.603	0.397
S94 Injury of nerves at ankle and foot level	0.603	0.397
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.603	0.397
S90 Superficial injury of ankle and foot	0.603	0.397
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.603	0.397
C95 Leukaemia of unspecified cell type	0.603	0.397
C94 Other leukaemias of specified cell type	0.603	0.397
C93 Monocytic leukaemia	0.603	0.397
C88 Malignant immunoproliferative diseases	0.603	0.397
C86 Other specified types of T/NK-cell lymphoma	0.603	0.397
C84 Peripheral and cutaneous T-cell lymphomas	0.603	0.397
S10 Superficial injury of neck	0.602	0.397
N76.2 Acute vulvitis	0.601	0.398
S67 Crushing injury of wrist and hand	0.601	0.398
B97.7 Papillomavirus as the cause of diseases classified to other chapters	0.601	0.399
N88.8 Other specified noninflammatory disorders of cervix uteri	0.601	0.399
W07 Fall involving chair	0.600	0.400
C44 Other malignant neoplasms of skin	0.599	0.401
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.599	0.401
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.599	0.401
S62 Fracture at wrist and hand level	0.598	0.401
S65 Injury of blood vessels at wrist and hand level	0.598	0.402
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.598	0.402
S60 Superficial injury of wrist and hand	0.598	0.402
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.598	0.402
M05 Seropositive rheumatoid arthritis	0.597	0.403
S01.8 Open wound of other parts of head	0.597	0.403
J34.8 Other specified disorders of nose and nasal sinuses	0.597	0.403
J02 Acute pharyngitis	0.596	0.404
E13 Other specified diabetes mellitus	0.596	0.404
E12 Malnutrition-related diabetes mellitus	0.596	0.404
J30 Vasomotor and allergic rhinitis	0.595	0.405
S06.0 Concussion	0.595	0.405
W13 Fall from, out of or through building or structure	0.595	0.405
F33.8 Other recurrent depressive disorders	0.594	0.405
F33.4 Recurrent depressive disorder, currently in remission	0.594	0.405
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms	0.594	0.405
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms	0.594	0.405
F33.1 Recurrent depressive disorder, current episode moderate	0.594	0.405
F33.0 Recurrent depressive disorder, current episode mild	0.594	0.405
C51 Malignant neoplasm of vulva	0.594	0.406
C91 Lymphoid leukaemia	0.594	0.406
M67.8 Other specified disorders of synovium and tendon	0.594	0.406
S61.1 Open wound of finger(s) with damage to nail	0.593	0.407
Y43.4 Immunosuppressive agents	0.593	0.407
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters	0.592	0.408
S49 Other and unspecified injuries of shoulder and upper arm	0.591	0.408
S48 Traumatic amputation of shoulder and upper arm	0.591	0.408
S46 Injury of muscle and tendon at shoulder and upper arm level	0.591	0.408
S45 Injury of blood vessels at shoulder and upper arm level	0.591	0.408
S44 Injury of nerves at shoulder and upper arm level	0.591	0.408
S41 Open wound of shoulder and upper arm	0.591	0.408
S47 Crushing injury of shoulder and upper arm	0.591	0.408
E14 Unspecified diabetes mellitus	0.591	0.409
N70 Salpingitis and oophoritis	0.590	0.409
M86-M90 Other osteopathies	0.590	0.410
I60-I69 Cerebrovascular diseases	0.590	0.410
N76.0 Acute vaginitis	0.590	0.410
S00 Superficial injury of head	0.590	0.410
H53 Visual disturbances	0.589	0.411
S68 Traumatic amputation of wrist and hand	0.587	0.413
J20-J22 Other acute lower respiratory infections	0.587	0.413
S82 Fracture of lower leg, including ankle	0.585	0.415
S92 Fracture of foot, except ankle	0.585	0.415
Y85.9 Sequelae of other and unspecified transport accidents	0.585	0.415
Y85.0 Sequelae of motor-vehicle accident	0.584	0.416
J32.0 Chronic maxillary sinusitis	0.584	0.416
N75.1 Abscess of Bartholin's gland	0.583	0.417
H57 Other disorders of eye and adnexa	0.583	0.417
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.582	0.418
X23 Contact with hornets, wasps and bees	0.581	0.419
S02.4 Fracture of malar and maxillary bones	0.581	0.419
W44.0 Home	0.581	0.419
S01.2 Open wound of nose	0.580	0.420
Q00-Q07 Congenital malformations of the nervous system	0.580	0.420
Y88.3 Sequelae of surgical and medical procedures as the cause of abnormal reaction of the patient or of later complication, without mention of misadventure at the time of the procedure	0.580	0.420
D72 Other disorders of white blood cells	0.579	0.421
B08 Other viral infections characterised by skin and mucous membrane lesions, not elsewhere classified	0.577	0.423
B06 Rubella [German measles]	0.577	0.423
B05 Measles	0.577	0.423
B01 Varicella [chickenpox]	0.577	0.423
B00 Herpesviral [herpes simplex] infections	0.577	0.423
B09 Unspecified viral infection characterised by skin and mucous membrane lesions	0.577	0.423
B04 Monkeypox	0.577	0.423
B03 Smallpox	0.577	0.423
W18 Other fall on same level	0.577	0.423
W16 Diving or jumping into water causing injury other than drowning or submersion	0.577	0.423
W15 Fall from cliff	0.577	0.423
W14 Fall from tree	0.577	0.423
W12 Fall on and from scaffolding	0.577	0.423
W11 Fall on and from ladder	0.577	0.423
W09 Fall involving playground equipment	0.577	0.423
W08 Fall involving other furniture	0.577	0.423
W06 Fall involving bed	0.577	0.423
W05 Fall involving wheelchair	0.577	0.423
W04 Fall while being carried or supported by other persons	0.577	0.423
W03 Other fall on same level due to collision with, or pushing by, another person	0.577	0.423
W02 Fall involving ice-skates, skis, roller-skates or skateboards	0.577	0.423
W01 Fall on same level from slipping, tripping and stumbling	0.577	0.423
W00 Fall on same level involving ice and snow	0.577	0.423
N39.3 Stress incontinence	0.577	0.423
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.576	0.424

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations