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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs117206365
log Bayes Factor = 12.4837
Chromosome 8   position 126,883,835  (GRCh37) Explore rs117206365 on Ensembl!
Variant rs117206365 is part of Cluster X0274

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter X Diseases of the respiratory system
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
J40-J47 Chronic lower respiratory diseases
1.000 0.000 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
1.000 0.000 0.000
J44 Other chronic obstructive pulmonary disease
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter VII Diseases of the eye and adnexa
0.996 0.004 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.995 0.005 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.995 0.005 0.000
M45-M49 Spondylopathies
0.985 0.015 0.000
H53-H54 Visual disturbances and blindness
0.983 0.017 0.000
C79 Secondary malignant neoplasm of other sites
0.979 0.021 0.000
M20-M25 Other joint disorders
0.971 0.029 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.969 0.031 0.000
H53 Visual disturbances
0.968 0.032 0.000
C78.7 Secondary malignant neoplasm of liver
0.967 0.033 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.956 0.044 0.000
Chapter I Certain infectious and parasitic diseases
0.953 0.047 0.000
J43 Emphysema
0.951 0.049 0.000
D10-D36 Benign neoplasms
0.951 0.049 0.000
M47 Spondylosis
0.951 0.049 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.948 0.052 0.000
J30-J39 Other diseases of upper respiratory tract
0.947 0.053 0.000
C80 Malignant neoplasm without specification of site
0.944 0.056 0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal
0.943 0.057 0.000
D12.6 Colon, unspecified
0.943 0.057 0.000
J34 Other disorders of nose and nasal sinuses
0.942 0.058 0.000
J20-J22 Other acute lower respiratory infections
0.938 0.062 0.000
C64-C68 Malignant neoplasms of urinary tract
0.934 0.066 0.000
D22 Melanocytic naevi
0.930 0.070 0.000
M20 Acquired deformities of fingers and toes
0.927 0.073 0.000
J34.2 Deviated nasal septum
0.926 0.074 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.924 0.076 0.000
H30-H36 Disorders of choroid and retina
0.924 0.076 0.000
J90-J94 Other diseases of pleura
0.922 0.078 0.000
M48 Other spondylopathies
0.922 0.078 0.000
M47.9 Spondylosis, unspecified
0.921 0.079 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.919 0.081 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.916 0.084 0.000
M15-M19 Arthrosis
0.912 0.088 0.000
C67 Malignant neoplasm of bladder
0.910 0.090 0.000
C34 Malignant neoplasm of bronchus and lung
0.907 0.093 0.000
M20.1 Hallux valgus (acquired)
0.907 0.093 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.904 0.096 0.000
M40-M43 Deforming dorsopathies
0.903 0.097 0.000
M19 Other arthrosis
0.899 0.101 0.000
J22 Unspecified acute lower respiratory infection
0.895 0.105 0.000
H53.2 Diplopia
0.895 0.105 0.000
J47 Bronchiectasis
0.893 0.107 0.000
J43.9 Emphysema, unspecified
0.891 0.109 0.000
M19.9 Arthrosis, unspecified
0.885 0.115 0.000
C67.9 Bladder, unspecified
0.880 0.120 0.000
H53.4 Visual field defects
0.878 0.122 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.876 0.124 0.000
D22.3 Melanocytic naevi of other and unspecified parts of face
0.876 0.124 0.000
Chapter VIII Diseases of the ear and mastoid process
0.873 0.127 0.000
M19.97 Arthrosis, unspecified (Ankle and foot)
0.871 0.129 0.000
M21 Other acquired deformities of limbs
0.870 0.130 0.000
J95-J99 Other diseases of the respiratory system
0.870 0.130 0.000
S00-S09 Injuries to the head
0.868 0.132 0.000
C78.2 Secondary malignant neoplasm of pleura
0.866 0.134 0.000
M48.0 Spinal stenosis
0.864 0.136 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.864 0.136 0.000
C34.1 Upper lobe, bronchus or lung
0.858 0.142 0.000
J90 Pleural effusion, not elsewhere classified
0.858 0.142 0.000
M47.96 Spondylosis, unspecified (Lumbar region)
0.856 0.144 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.855 0.145 0.000
B95-B98 Bacterial, viral and other infectious agents
0.853 0.147 0.000
J34.3 Hypertrophy of nasal turbinates
0.850 0.150 0.000
H53.1 Subjective visual disturbances
0.849 0.151 0.000
C80.0 Malignant neoplasm, primary site unknown, so stated
0.842 0.158 0.000
C78.0 Secondary malignant neoplasm of lung
0.842 0.158 0.000
D22.5 Melanocytic naevi of trunk
0.840 0.160 0.000
C80.9 Malignant neoplasm, unspecified
0.837 0.163 0.000
M80-M85 Disorders of bone density and structure
0.837 0.163 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.836 0.164 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.829 0.171 0.000
M05-M14 Inflammatory polyarthropathies
0.826 0.174 0.000
E00-E07 Disorders of thyroid gland
0.825 0.175 0.000
Chapter XX External causes of morbidity and mortality
0.820 0.180 0.000
D12.8 Rectum
0.818 0.182 0.000
H43-H45 Disorders of vitreous body and globe
0.816 0.184 0.000
J09-J18 Influenza and pneumonia
0.816 0.184 0.000
C15-C26 Malignant neoplasms of digestive organs
0.816 0.184 0.000
S01 Open wound of head
0.814 0.186 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.811 0.189 0.000
A30-A49 Other bacterial diseases
0.807 0.192 0.000
H54 Blindness and low vision
0.807 0.193 0.000
B15-B19 Viral hepatitis
0.806 0.194 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.805 0.195 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.803 0.197 0.000
M65-M68 Disorders of synovium and tendon
0.801 0.199 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.801 0.199 0.000
M43 Other deforming dorsopathies
0.800 0.200 0.000
J43.2 Centrilobular emphysema
0.797 0.202 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.796 0.204 0.000
H36 Retinal disorders in diseases classified elsewhere
0.791 0.209 0.000
H52 Disorders of refraction and accommodation
0.791 0.209 0.000
M48.06 Spinal stenosis (Lumbar region)
0.791 0.209 0.000
D22.6 Melanocytic naevi of upper limb, including shoulder
0.790 0.210 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.790 0.210 0.000
H53.9 Visual disturbance, unspecified
0.789 0.211 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.787 0.213 0.000
M06 Other rheumatoid arthritis
0.787 0.213 0.000
H50 Other strabismus
0.785 0.215 0.000
S10-S19 Injuries to the neck
0.783 0.217 0.000
Chapter IX Diseases of the circulatory system
0.783 0.217 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.782 0.218 0.000
M22 Disorders of patella
0.779 0.221 0.000
H31 Other disorders of choroid
0.778 0.222 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.778 0.222 0.000
J98 Other respiratory disorders
0.775 0.225 0.000
S01.8 Open wound of other parts of head
0.773 0.227 0.000
S20-S29 Injuries to the thorax
0.771 0.229 0.000
E20-E35 Disorders of other endocrine glands
0.769 0.231 0.000
Chapter XXII Codes for special purposes
0.768 0.232 0.000
H30 Chorioretinal inflammation
0.768 0.232 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.766 0.234 0.000
H60-H62 Diseases of external ear
0.766 0.234 0.000
J34.8 Other specified disorders of nose and nasal sinuses
0.764 0.236 0.000
E03 Other hypothyroidism
0.763 0.237 0.000
M47.92 Spondylosis, unspecified (Cervical region)
0.759 0.241 0.000
J37 Chronic laryngitis and laryngotracheitis
0.759 0.241 0.000
H90-H95 Other disorders of ear
0.757 0.243 0.000
J00-J06 Acute upper respiratory infections
0.753 0.247 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.752 0.248 0.000
M06.9 Rheumatoid arthritis, unspecified
0.751 0.249 0.000
J93 Pneumothorax
0.748 0.252 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.746 0.254 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.744 0.256 0.000
H35 Other retinal disorders
0.743 0.257 0.000
M19.98 Arthrosis, unspecified (Other)
0.742 0.258 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.740 0.260 0.000
T66-T78 Other and unspecified effects of external causes
0.739 0.261 0.000
I30-I52 Other forms of heart disease
0.739 0.261 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.739 0.261 0.000
M47.99 Spondylosis, unspecified (Site unspecified)
0.738 0.262 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.737 0.263 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.736 0.264 0.000
M48.02 Spinal stenosis (Cervical region)
0.736 0.264 0.000
D12.9 Anus and anal canal
0.735 0.265 0.000
E40-E46 Malnutrition
0.733 0.267 0.000
M21.2 Flexion deformity
0.732 0.268 0.000
M20.0 Deformity of finger(s)
0.732 0.268 0.000
D18 Haemangioma and lymphangioma, any site
0.731 0.269 0.000
T79-T79 Certain early complications of trauma
0.731 0.269 0.000
M41 Scoliosis
0.730 0.270 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.730 0.270 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.729 0.271 0.000
M19.0 Primary arthrosis of other joints
0.729 0.271 0.000
M43.1 Spondylolisthesis
0.726 0.274 0.000
M47.2 Other spondylosis with radiculopathy
0.724 0.276 0.000
M48.5 Collapsed vertebra, not elsewhere classified
0.724 0.276 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.723 0.277 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.722 0.278 0.000
J46 Status asthmaticus
0.720 0.280 0.000
M23 Internal derangement of knee
0.720 0.280 0.000
E03.9 Hypothyroidism, unspecified
0.719 0.281 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.719 0.281 0.000
A46 Erysipelas
0.719 0.281 0.000
H10-H13 Disorders of conjunctiva
0.718 0.282 0.000
D30 Benign neoplasm of urinary organs
0.718 0.282 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
J41 Simple and mucopurulent chronic bronchitis
0.717 0.283 0.000
S50-S59 Injuries to the elbow and forearm
0.717 0.283 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.716 0.284 0.000
M19.94 Arthrosis, unspecified (Hand)
0.716 0.284 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.716 0.284 0.000
M20.3 Other deformity of hallux (acquired)
0.714 0.286 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.713 0.287 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.713 0.287 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.713 0.287 0.000
H18 Other disorders of cornea
0.712 0.288 0.000
C34.9 Bronchus or lung, unspecified
0.712 0.288 0.000
H54.7 Unspecified visual loss
0.711 0.289 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.710 0.290 0.000
D22.4 Melanocytic naevi of scalp and neck
0.710 0.290 0.000
H43 Disorders of vitreous body
0.709 0.291 0.000
M86-M90 Other osteopathies
0.709 0.291 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.709 0.291 0.000
C79.6 Secondary malignant neoplasm of ovary
0.708 0.291 0.000
S70-S79 Injuries to the hip and thigh
0.708 0.292 0.000
M21.4 Flat foot [pes planus] (acquired)
0.708 0.292 0.000
C67.6 Ureteric orifice
0.708 0.292 0.000
M24 Other specific joint derangements
0.707 0.292 0.000
A80-A89 Viral infections of the central nervous system
0.707 0.293 0.000
M91-M94 Chondropathies
0.707 0.293 0.000
M49 Spondylopathies in diseases classified elsewhere
0.706 0.294 0.000
C73 Malignant neoplasm of thyroid gland
0.706 0.294 0.000
H55-H59 Other disorders of eye and adnexa
0.706 0.294 0.000
C32 Malignant neoplasm of larynx
0.705 0.294 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.704 0.296 0.000
T90 Sequelae of injuries of head
0.703 0.297 0.000
D46 Myelodysplastic syndromes
0.703 0.297 0.000
E50-E64 Other nutritional deficiencies
0.702 0.297 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.702 0.298 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.702 0.298 0.000
D17 Benign lipomatous neoplasm
0.702 0.298 0.000
C67.5 Bladder neck
0.702 0.298 0.000
I35 Nonrheumatic aortic valve disorders
0.698 0.302 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.697 0.303 0.000
I47 Paroxysmal tachycardia
0.697 0.303 0.000
M47.1 Other spondylosis with myelopathy
0.697 0.303 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.697 0.303 0.000
H36.0 Diabetic retinopathy
0.696 0.304 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.696 0.304 0.000
M33 Dermatopolymyositis
0.696 0.304 0.000
M32 Systemic lupus erythematosus
0.696 0.304 0.000
M30 Polyarteritis nodosa and related conditions
0.696 0.304 0.000
J31.0 Chronic rhinitis
0.696 0.304 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.696 0.304 0.000
C15 Malignant neoplasm of oesophagus
0.695 0.305 0.000
H53.6 Night blindness
0.694 0.306 0.000
H53.5 Colour vision deficiencies
0.694 0.306 0.000
H53.3 Other disorders of binocular vision
0.694 0.306 0.000
Chapter VI Diseases of the nervous system
0.694 0.306 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.694 0.306 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.693 0.307 0.000
B35-B49 Mycoses
0.693 0.307 0.000
C67.4 Posterior wall of bladder
0.693 0.307 0.000
H53.8 Other visual disturbances
0.692 0.308 0.000
M34 Systemic sclerosis
0.691 0.309 0.000
M47.90 Spondylosis, unspecified (Multiple sites in spine)
0.691 0.309 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.690 0.310 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.690 0.310 0.000
M47.97 Spondylosis, unspecified (Lumbosacral region)
0.690 0.310 0.000
S00 Superficial injury of head
0.689 0.311 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.689 0.311 0.000
M47.8 Other spondylosis
0.687 0.313 0.000
D32 Benign neoplasm of meninges
0.687 0.313 0.000
C34.2 Middle lobe, bronchus or lung
0.687 0.313 0.000
T33-T35 Frostbite
0.686 0.314 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.686 0.314 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.686 0.314 0.000
T00-T07 Injuries involving multiple body regions
0.686 0.314 0.000
D26 Other benign neoplasms of uterus
0.686 0.314 0.000
D34 Benign neoplasm of thyroid gland
0.684 0.315 0.000
B99-B99 Other infectious diseases
0.683 0.317 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.683 0.317 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.683 0.317 0.000
B65-B83 Helminthiases
0.683 0.317 0.000
B50-B64 Protozoal diseases
0.683 0.317 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.683 0.317 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.683 0.317 0.000
A75-A79 Rickettsioses
0.683 0.317 0.000
A70-A74 Other diseases caused by chlamydiae
0.683 0.317 0.000
A65-A69 Other spirochaetal diseases
0.683 0.317 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.683 0.317 0.000
A20-A28 Certain zoonotic bacterial diseases
0.683 0.317 0.000
A15-A19 Tuberculosis
0.683 0.317 0.000
D14 Benign neoplasm of middle ear and respiratory system
0.682 0.318 0.000
M20.6 Acquired deformity of toe(s), unspecified
0.682 0.318 0.000
J43.8 Other emphysema
0.682 0.318 0.000
J43.1 Panlobular emphysema
0.682 0.318 0.000
J43.0 MacLeod's syndrome
0.682 0.318 0.000
D31 Benign neoplasm of eye and adnexa
0.682 0.318 0.000
D29 Benign neoplasm of male genital organs
0.682 0.318 0.000
D28 Benign neoplasm of other and unspecified female genital organs
0.682 0.318 0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum
0.682 0.318 0.000
D19 Benign neoplasm of mesothelial tissue
0.682 0.318 0.000
D16 Benign neoplasm of bone and articular cartilage
0.682 0.318 0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs
0.682 0.318 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.682 0.318 0.000
H20 Iridocyclitis
0.681 0.319 0.000
M45 Ankylosing spondylitis
0.680 0.320 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.680 0.320 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.680 0.320 0.000
C31 Malignant neoplasm of accessory sinuses
0.680 0.320 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.680 0.320 0.000
C37 Malignant neoplasm of thymus
0.680 0.320 0.000
C33 Malignant neoplasm of trachea
0.680 0.320 0.000
M80 Osteoporosis with pathological fracture
0.680 0.320 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.680 0.320 0.000
J06 Acute upper respiratory infections of multiple and unspecified sites
0.679 0.321 0.000
A00-A09 Intestinal infectious diseases
0.679 0.321 0.000
J40 Bronchitis, not specified as acute or chronic
0.678 0.321 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.678 0.322 0.000
S01.0 Open wound of scalp
0.677 0.323 0.000
D12.1 Appendix
0.676 0.324 0.000
H49 Paralytic strabismus
0.676 0.324 0.000
J34.1 Cyst and mucocele of nose and nasal sinus
0.675 0.325 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.675 0.325 0.000
C34.3 Lower lobe, bronchus or lung
0.673 0.327 0.000
J21 Acute bronchiolitis
0.673 0.327 0.000
D00-D09 In situ neoplasms
0.672 0.328 0.000
I35.0 Aortic (valve) stenosis
0.672 0.328 0.000
D37.6 Liver, gallbladder and bile ducts
0.671 0.329 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.670 0.329 0.000
I78 Diseases of capillaries
0.670 0.330 0.000
S05 Injury of eye and orbit
0.670 0.330 0.000
C68 Malignant neoplasm of other and unspecified urinary organs
0.670 0.330 0.000
C66 Malignant neoplasm of ureter
0.670 0.330 0.000
C65 Malignant neoplasm of renal pelvis
0.670 0.330 0.000
H90 Conductive and sensorineural hearing loss
0.670 0.330 0.000
J34.0 Abscess, furuncle and carbuncle of nose
0.669 0.331 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.668 0.332 0.000
I45 Other conduction disorders
0.667 0.333 0.000
D22.9 Melanocytic naevi, unspecified
0.667 0.333 0.000
D22.2 Melanocytic naevi of ear and external auricular canal
0.667 0.333 0.000
H54.9 Unspecified visual impairment (binocular)
0.667 0.333 0.000
C17 Malignant neoplasm of small intestine
0.667 0.333 0.000
T87 Complications peculiar to reattachment and amputation
0.666 0.334 0.000
D12.7 Rectosigmoid junction
0.665 0.334 0.000
J20 Acute bronchitis
0.665 0.335 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.664 0.335 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.664 0.336 0.000
H50.0 Convergent concomitant strabismus
0.664 0.336 0.000
M84 Disorders of continuity of bone
0.663 0.337 0.000
W20-W49 Exposure to inanimate mechanical forces
0.663 0.337 0.000
B18 Chronic viral hepatitis
0.663 0.337 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.662 0.337 0.000
J94 Other pleural conditions
0.661 0.339 0.000
M48.9 Spondylopathy, unspecified
0.661 0.339 0.000
M48.8 Other specified spondylopathies
0.661 0.339 0.000
M48.4 Fatigue fracture of vertebra
0.661 0.339 0.000
M48.3 Traumatic spondylopathy
0.661 0.339 0.000
M48.2 Kissing spine
0.661 0.339 0.000
M48.1 Ankylosing hyperostosis [Forestier]
0.661 0.339 0.000
M19.99 Arthrosis, unspecified (Site unspecified)
0.661 0.339 0.000
M47.98 Spondylosis, unspecified (Sacral and sacrococcygeal region)
0.660 0.340 0.000
M47.95 Spondylosis, unspecified (Thoracolumbar region)
0.660 0.340 0.000
M47.94 Spondylosis, unspecified (Thoracic region)
0.660 0.340 0.000
M47.93 Spondylosis, unspecified (Cervicothoracic region)
0.660 0.340 0.000
M47.91 Spondylosis, unspecified (Occipito-atlanto-axial region)
0.660 0.340 0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot
0.659 0.341 0.000
M19.96 Arthrosis, unspecified-Lower leg
0.659 0.341 0.000
I47.2 Ventricular tachycardia
0.659 0.341 0.000
H17 Corneal scars and opacities
0.659 0.341 0.000
I44 Atrioventricular and left bundle-branch block
0.658 0.342 0.000
D12.2 Ascending colon
0.658 0.342 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.658 0.342 0.000
A49 Bacterial infection of unspecified site
0.657 0.343 0.000
Y40 Systemic antibiotics
0.657 0.343 0.000
J92 Pleural plaque
0.657 0.343 0.000
H51 Other disorders of binocular movement
0.656 0.343 0.000
H30.9 Chorioretinal inflammation, unspecified
0.656 0.344 0.000
D21 Other benign neoplasms of connective and other soft tissue
0.656 0.344 0.000
S90-S99 Injuries to the ankle and foot
0.656 0.344 0.000
M66 Spontaneous rupture of synovium and tendon
0.654 0.346 0.000
M15 Polyarthrosis
0.654 0.346 0.000
M19.91 Arthrosis, unspecified (Shoulder region)
0.653 0.347 0.000
C67.8 Overlapping lesion of bladder
0.653 0.347 0.000
C67.7 Urachus
0.653 0.347 0.000
C67.3 Anterior wall of bladder
0.653 0.347 0.000
C67.1 Dome of bladder
0.653 0.347 0.000
C67.0 Trigone of bladder
0.653 0.347 0.000
H52.1 Myopia
0.652 0.348 0.000
D12.0 Caecum
0.652 0.348 0.000
E06 Thyroiditis
0.652 0.348 0.000
C34.8 Overlapping lesion of bronchus and lung
0.650 0.349 0.000
C34.0 Main bronchus
0.650 0.349 0.000
H92 Otalgia and effusion of ear
0.650 0.350 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.649 0.351 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.648 0.352 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.648 0.352 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.648 0.352 0.000
V10-V19 Pedal cyclist injured in transport accident
0.648 0.352 0.000
M42 Spinal osteochondrosis
0.647 0.353 0.000
M40 Kyphosis and lordosis
0.647 0.353 0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters
0.647 0.353 0.000
H60 Otitis externa
0.647 0.353 0.000
E07 Other disorders of thyroid
0.645 0.355 0.000
J98.8 Other specified respiratory disorders
0.645 0.355 0.000
I73 Other peripheral vascular diseases
0.645 0.355 0.000
M19.8 Other specified arthrosis
0.645 0.355 0.000
M19.2 Other secondary arthrosis
0.645 0.355 0.000
M19.1 Posttraumatic arthrosis of other joints
0.645 0.355 0.000
M21.1 Varus deformity, not elsewhere classified
0.645 0.355 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.643 0.357 0.000
J98.0 Diseases of bronchus, not elsewhere classified
0.642 0.358 0.000
D35 Benign neoplasm of other and unspecified endocrine glands
0.641 0.359 0.000
C67.2 Lateral wall of bladder
0.641 0.359 0.000
J98.1 Pulmonary collapse
0.641 0.359 0.000
X20-X29 Contact with venomous animals and plants
0.641 0.359 0.000
J60-J70 Lung diseases due to external agents
0.640 0.359 0.000
B16 Acute hepatitis B
0.639 0.361 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.639 0.361 0.000
E27 Other disorders of adrenal gland
0.639 0.361 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.638 0.362 0.000
C79.2 Secondary malignant neoplasm of skin
0.638 0.362 0.000
M22.8 Other disorders of patella
0.638 0.362 0.000
M67 Other disorders of synovium and tendon
0.636 0.364 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.635 0.365 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.635 0.365 0.000
J86 Pyothorax
0.634 0.365 0.000
M35 Other systemic involvement of connective tissue
0.634 0.366 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.634 0.366 0.000
S12 Fracture of neck
0.633 0.367 0.000
S51 Open wound of forearm
0.632 0.367 0.000
S06 Intracranial injury
0.632 0.368 0.000
E46 Unspecified protein-energy malnutrition
0.631 0.369 0.000
H80-H83 Diseases of inner ear
0.631 0.369 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.630 0.370 0.000
H31.8 Other specified disorders of choroid
0.630 0.370 0.000
M20.4 Other hammer toe(s) (acquired)
0.629 0.371 0.000
S01.7 Multiple open wounds of head
0.629 0.371 0.000
D11 Benign neoplasm of major salivary glands
0.629 0.371 0.000
M19.92 Arthrosis, unspecified (Upper arm)
0.628 0.372 0.000
D22.0 Melanocytic naevi of lip
0.627 0.373 0.000
M21.3 Wrist or foot drop (acquired)
0.627 0.373 0.000
J06.9 Acute upper respiratory infection, unspecified
0.626 0.374 0.000
H61 Other disorders of external ear
0.626 0.374 0.000
I77 Other disorders of arteries and arterioles
0.625 0.375 0.000
M46 Other inflammatory spondylopathies
0.624 0.375 0.000
J37.0 Chronic laryngitis
0.624 0.376 0.000
C18 Malignant neoplasm of colon
0.624 0.376 0.000
M21.9 Acquired deformity of limb, unspecified
0.624 0.376 0.000
M21.8 Other specified acquired deformities of limbs
0.624 0.376 0.000
M21.7 Unequal limb length (acquired)
0.624 0.376 0.000
M21.6 Other acquired deformities of ankle and foot
0.624 0.376 0.000
J96 Respiratory failure, not elsewhere classified
0.623 0.376 0.000
H31.0 Chorioretinal scars
0.623 0.377 0.000
M22.4 Chondromalacia patellae
0.623 0.377 0.000
J93.9 Pneumothorax, unspecified
0.623 0.377 0.000
S08 Traumatic amputation of part of head
0.622 0.378 0.000
S07 Crushing injury of head
0.622 0.378 0.000
S04 Injury of cranial nerves
0.622 0.378 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.622 0.378 0.000
I74 Arterial embolism and thrombosis
0.622 0.378 0.000
S00.8 Superficial injury of other parts of head
0.622 0.378 0.000
H52.2 Astigmatism
0.621 0.379 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.621 0.379 0.000
H50.9 Strabismus, unspecified
0.621 0.379 0.000
M21.0 Valgus deformity, not elsewhere classified
0.620 0.380 0.000
M48.08 Spinal stenosis (Sacral and sacrococcygeal region)
0.619 0.381 0.000
M48.05 Spinal stenosis (Thoracolumbar region)
0.619 0.381 0.000
M48.04 Spinal stenosis (Thoracic region)
0.619 0.381 0.000
M48.03 Spinal stenosis (Cervicothoracic region)
0.619 0.381 0.000
M48.01 Spinal stenosis (Occipito-atlanto-axial region)
0.619 0.381 0.000
M48.00 Spinal stenosis (Multiple sites in spine)
0.619 0.381 0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere
0.619 0.381 0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere
0.619 0.381 0.000
H16 Keratitis
0.619 0.381 0.000
H15 Disorders of sclera
0.619 0.381 0.000
M19.01 Primary arthrosis of other joints (Shoulder region)
0.619 0.381 0.000
H21 Other disorders of iris and ciliary body
0.619 0.381 0.000
Y52 Agents primarily affecting the cardiovascular system
0.619 0.381 0.000
M43.17 Spondylolisthesis (Lumbosacral region)
0.618 0.382 0.000
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters
0.618 0.382 0.000
M31 Other necrotising vasculopathies
0.615 0.384 0.000
J10 Influenza due to identified influenza virus
0.616 0.384 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.615 0.385 0.000
M06.0 Seronegative rheumatoid arthritis
0.615 0.385 0.000
C50-C50 Malignant neoplasm of breast
0.614 0.386 0.000
D36 Benign neoplasm of other and unspecified sites
0.613 0.387 0.000
T86 Failure and rejection of transplanted organs and tissues
0.613 0.387 0.000
D37.1 Stomach
0.612 0.388 0.000
M81 Osteoporosis without pathological fracture
0.612 0.388 0.000
M48.09 Spinal stenosis (Site unspecified)
0.612 0.388 0.000
J39 Other diseases of upper respiratory tract
0.612 0.388 0.000
J42 Unspecified chronic bronchitis
0.611 0.389 0.000
D22.7 Melanocytic naevi of lower limb, including hip
0.611 0.389 0.000
S01.2 Open wound of nose
0.610 0.390 0.000
D33 Benign neoplasm of brain and other parts of central nervous system
0.610 0.390 0.000
E23 Hypofunction and other disorders of pituitary gland
0.610 0.390 0.000
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)
0.608 0.392 0.000
I44.2 Atrioventricular block, complete
0.608 0.392 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.607 0.393 0.000
M41.9 Scoliosis, unspecified
0.607 0.393 0.000
J84 Other interstitial pulmonary diseases
0.607 0.393 0.000
S27 Injury of other and unspecified intrathoracic organs
0.605 0.395 0.000
Y48 Anaesthetics and therapeutic gases
0.605 0.395 0.000
J32 Chronic sinusitis
0.604 0.396 0.000
M48.07 Spinal stenosis (Lumbosacral region)
0.604 0.396 0.000
M19.93 Arthrosis, unspecified (Forearm)
0.604 0.396 0.000
D17.2 Benign lipomatous neoplasm of skin and subcutaneous tissue of limbs
0.604 0.396 0.000
M25 Other joint disorders, not elsewhere classified
0.603 0.397 0.000
I78.1 Naevus, nonneoplastic
0.602 0.398 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.601 0.398 0.000
D10 Benign neoplasm of mouth and pharynx
0.601 0.399 0.000
V80-V89 Other land transport accidents
0.601 0.399 0.000
M83 Adult osteomalacia
0.600 0.400 0.000
M82 Osteoporosis in diseases classified elsewhere
0.600 0.400 0.000
D47.3 Essential (haemorrhagic) thrombocythaemia
0.600 0.400 0.000
S19 Other and unspecified injuries of neck
0.600 0.400 0.000
S01.9 Open wound of head, part unspecified
0.600 0.400 0.000
O60-O75 Complications of labour and delivery
0.600 0.400 0.000
M47.22 Other spondylosis with radiculopathy (Cervical region)
0.599 0.400 0.000
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters
0.599 0.401 0.000
C22.0 Liver cell carcinoma
0.599 0.401 0.000
H43.8 Other disorders of vitreous body
0.599 0.401 0.000
I71 Aortic aneurysm and dissection
0.599 0.401 0.000
M21.27 Flexion deformity (Ankle and foot)
0.598 0.402 0.000
B98.0 Helicobacter pylori [H.pylori] as the cause of diseases classified to other chapters
0.597 0.403 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.597 0.403 0.000
E53 Deficiency of other B group vitamins
0.596 0.403 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.596 0.404 0.000
D17.5 Benign lipomatous neoplasm of intra-abdominal organs
0.596 0.404 0.000
J91 Pleural effusion in conditions classified elsewhere
0.595 0.405 0.000
D37.7 Other digestive organs
0.595 0.405 0.000
C15.5 Lower third of oesophagus
0.594 0.406 0.000
C75 Malignant neoplasm of other endocrine glands and related structures
0.594 0.406 0.000
C74 Malignant neoplasm of adrenal gland
0.594 0.406 0.000
M19.95 Arthrosis, unspecified (Pelvic region and thigh)
0.593 0.406 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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