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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs117256623
log Bayes Factor = 13.2359
Chromosome 10   position 123,454,174  (GRCh37) Explore rs117256623 on Ensembl!
Variant rs117256623 is part of Cluster X0277

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
I25 Chronic ischaemic heart disease
1.000 0.000 0.000
I30-I52 Other forms of heart disease
0.998 0.002 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.998 0.002 0.000
Chapter V Mental and behavioural disorders
0.998 0.002 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.987 0.013 0.000
Chapter II Neoplasms
0.986 0.014 0.000
C50-C50 Malignant neoplasm of breast
0.984 0.016 0.000
C50 Malignant neoplasm of breast
0.984 0.016 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.981 0.019 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.979 0.021 0.000
I25.1 Atherosclerotic heart disease
0.978 0.022 0.000
Chapter VII Diseases of the eye and adnexa
0.978 0.022 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.976 0.024 0.000
I51 Complications and ill-defined descriptions of heart disease
0.974 0.026 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.972 0.028 0.000
C50.9 Breast, unspecified
0.970 0.030 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.959 0.041 0.000
H40-H42 Glaucoma
0.957 0.043 0.000
L82 Seborrhoeic keratosis
0.956 0.044 0.000
F30-F39 Mood [affective] disorders
0.952 0.048 0.000
I47 Paroxysmal tachycardia
0.950 0.050 0.000
Chapter XX External causes of morbidity and mortality
0.950 0.050 0.000
S00-S09 Injuries to the head
0.946 0.054 0.000
H40 Glaucoma
0.942 0.058 0.000
I21 Acute myocardial infarction
0.942 0.058 0.000
C50.1 Central portion of breast
0.930 0.070 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.926 0.074 0.000
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified
0.924 0.076 0.000
I47.2 Ventricular tachycardia
0.921 0.079 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.917 0.083 0.000
I25.2 Old myocardial infarction
0.917 0.083 0.000
I60-I69 Cerebrovascular diseases
0.914 0.086 0.000
S00 Superficial injury of head
0.908 0.092 0.000
F31 Bipolar affective disorder
0.904 0.096 0.000
H40.2 Primary angle-closure glaucoma
0.896 0.104 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.895 0.105 0.000
I73 Other peripheral vascular diseases
0.894 0.106 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.890 0.110 0.000
C50.2 Upper-inner quadrant of breast
0.887 0.113 0.000
I50 Heart failure
0.887 0.113 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.886 0.114 0.000
I44 Atrioventricular and left bundle-branch block
0.884 0.116 0.000
L98.9 Disorder of skin and subcutaneous tissue, unspecified
0.884 0.116 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.884 0.116 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.877 0.123 0.000
E65-E68 Obesity and other hyperalimentation
0.875 0.125 0.000
Chapter I Certain infectious and parasitic diseases
0.873 0.127 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.872 0.128 0.000
S00.8 Superficial injury of other parts of head
0.871 0.129 0.000
E70-E90 Metabolic disorders
0.869 0.131 0.000
I51.8 Other ill-defined heart diseases
0.869 0.131 0.000
I51.7 Cardiomegaly
0.867 0.133 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.866 0.134 0.000
I34 Nonrheumatic mitral valve disorders
0.862 0.138 0.000
Chapter XXII Codes for special purposes
0.861 0.139 0.000
C51-C58 Malignant neoplasms of female genital organs
0.860 0.140 0.000
H30-H36 Disorders of choroid and retina
0.859 0.141 0.000
T66-T78 Other and unspecified effects of external causes
0.853 0.147 0.000
I51.9 Heart disease, unspecified
0.853 0.147 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.852 0.148 0.000
I73.9 Peripheral vascular disease, unspecified
0.847 0.153 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.843 0.157 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.842 0.158 0.000
I20 Angina pectoris
0.841 0.159 0.000
F31.9 Bipolar affective disorder, unspecified
0.841 0.159 0.000
Y95 Nosocomial condition
0.840 0.160 0.000
H40.0 Glaucoma suspect
0.838 0.162 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.835 0.165 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.834 0.166 0.000
F99-F99 Unspecified mental disorder
0.832 0.168 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.831 0.169 0.000
L89 Decubitus ulcer
0.831 0.169 0.000
I72 Other aneurysm
0.826 0.174 0.000
I45 Other conduction disorders
0.824 0.176 0.000
M70-M79 Other soft tissue disorders
0.823 0.177 0.000
M80-M85 Disorders of bone density and structure
0.819 0.181 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.818 0.182 0.000
I50.9 Heart failure, unspecified
0.816 0.184 0.000
S09 Other and unspecified injuries of head
0.816 0.184 0.000
E66 Obesity
0.816 0.184 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.816 0.184 0.000
I78 Diseases of capillaries
0.814 0.186 0.000
I20.9 Angina pectoris, unspecified
0.811 0.189 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.809 0.191 0.000
Chapter XIV Diseases of the genitourinary system
0.807 0.193 0.000
I25.3 Aneurysm of heart
0.806 0.194 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.805 0.195 0.000
I44.0 Atrioventricular block, first degree
0.801 0.198 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.801 0.199 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.801 0.199 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.794 0.206 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.793 0.207 0.000
S10-S19 Injuries to the neck
0.792 0.208 0.000
E66.9 Obesity, unspecified
0.792 0.208 0.000
S00.0 Superficial injury of scalp
0.789 0.211 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.786 0.214 0.000
I71 Aortic aneurysm and dissection
0.785 0.215 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.783 0.217 0.000
I31 Other diseases of pericardium
0.780 0.220 0.000
E50-E64 Other nutritional deficiencies
0.780 0.220 0.000
T86 Failure and rejection of transplanted organs and tissues
0.779 0.221 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.778 0.222 0.000
I74 Arterial embolism and thrombosis
0.777 0.223 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.776 0.224 0.000
I65.2 Occlusion and stenosis of carotid artery
0.776 0.224 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.774 0.226 0.000
B35-B49 Mycoses
0.774 0.226 0.000
S90-S99 Injuries to the ankle and foot
0.773 0.227 0.000
C50.4 Upper-outer quadrant of breast
0.771 0.228 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.771 0.229 0.000
F32 Depressive episode
0.770 0.230 0.000
M80 Osteoporosis with pathological fracture
0.767 0.233 0.000
H40.9 Glaucoma, unspecified
0.766 0.234 0.000
D00-D09 In situ neoplasms
0.762 0.238 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.762 0.238 0.000
S20-S29 Injuries to the thorax
0.761 0.239 0.000
I22 Subsequent myocardial infarction
0.761 0.239 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.761 0.239 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.758 0.242 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.757 0.242 0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts
0.757 0.243 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.754 0.246 0.000
E20-E35 Disorders of other endocrine glands
0.754 0.246 0.000
I34.0 Mitral (valve) insufficiency
0.753 0.247 0.000
F60-F69 Disorders of adult personality and behaviour
0.753 0.247 0.000
T78 Adverse effects, not elsewhere classified
0.750 0.250 0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system
0.745 0.255 0.000
V20-V29 Motorcycle rider injured in transport accident
0.743 0.257 0.000
E83 Disorders of mineral metabolism
0.742 0.258 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.742 0.258 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.741 0.258 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.741 0.259 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.740 0.260 0.000
L81 Other disorders of pigmentation
0.740 0.260 0.000
I44.7 Left bundle-branch block, unspecified
0.736 0.264 0.000
F80-F89 Disorders of psychological development
0.735 0.265 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.734 0.266 0.000
T87 Complications peculiar to reattachment and amputation
0.734 0.266 0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms
0.733 0.267 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.733 0.267 0.000
I77 Other disorders of arteries and arterioles
0.732 0.268 0.000
T79-T79 Certain early complications of trauma
0.732 0.268 0.000
X60-X84 Intentional self-harm
0.732 0.268 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.730 0.270 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.729 0.271 0.000
M50-M54 Other dorsopathies
0.728 0.272 0.000
I10-I15 Hypertensive diseases
0.728 0.272 0.000
L98.8 Other specified disorders of skin and subcutaneous tissue
0.727 0.273 0.000
F40 Phobic anxiety disorders
0.724 0.276 0.000
W20-W49 Exposure to inanimate mechanical forces
0.724 0.276 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.723 0.277 0.000
M75 Shoulder lesions
0.723 0.277 0.000
S70-S79 Injuries to the hip and thigh
0.723 0.277 0.000
E87.5 Hyperkalaemia
0.722 0.278 0.000
M80.9 Unspecified osteoporosis with pathological fracture
0.721 0.279 0.000
N10-N16 Renal tubulo-interstitial diseases
0.719 0.281 0.000
F10.1 Harmful use
0.718 0.282 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I23 Certain current complications following acute myocardial infarction
0.717 0.283 0.000
I25.6 Silent myocardial ischaemia
0.717 0.283 0.000
I25.4 Coronary artery aneurysm
0.717 0.283 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.717 0.283 0.000
I52 Other heart disorders in diseases classified elsewhere
0.716 0.284 0.000
I48 Atrial fibrillation and flutter
0.716 0.284 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.716 0.284 0.000
I41 Myocarditis in diseases classified elsewhere
0.716 0.284 0.000
I40 Acute myocarditis
0.716 0.284 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.716 0.284 0.000
I37 Pulmonary valve disorders
0.716 0.284 0.000
I36 Nonrheumatic tricuspid valve disorders
0.716 0.284 0.000
I32 Pericarditis in diseases classified elsewhere
0.716 0.284 0.000
I30 Acute pericarditis
0.716 0.284 0.000
T33-T35 Frostbite
0.716 0.284 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.716 0.284 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.716 0.284 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.716 0.284 0.000
T00-T07 Injuries involving multiple body regions
0.716 0.284 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.715 0.285 0.000
F70-F79 Mental retardation
0.715 0.285 0.000
L20-L30 Dermatitis and eczema
0.715 0.285 0.000
I72.4 Aneurysm of artery of lower extremity
0.715 0.285 0.000
N30-N39 Other diseases of urinary system
0.714 0.286 0.000
F99 Mental disorder, not otherwise specified
0.714 0.286 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.714 0.286 0.000
B15-B19 Viral hepatitis
0.714 0.286 0.000
H34 Retinal vascular occlusions
0.713 0.287 0.000
L89.2 Stage III decubitus ulcer
0.712 0.288 0.000
I70 Atherosclerosis
0.712 0.288 0.000
L90 Atrophic disorders of skin
0.711 0.289 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.710 0.290 0.000
C50.3 Lower-inner quadrant of breast
0.707 0.293 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.707 0.293 0.000
X20-X29 Contact with venomous animals and plants
0.706 0.294 0.000
C50.6 Axillary tail of breast
0.705 0.295 0.000
C50.0 Nipple and areola
0.705 0.295 0.000
H55-H59 Other disorders of eye and adnexa
0.705 0.295 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.704 0.296 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.704 0.296 0.000
E85 Amyloidosis
0.703 0.297 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.702 0.297 0.000
L10-L14 Bullous disorders
0.702 0.298 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.702 0.298 0.000
E40-E46 Malnutrition
0.701 0.299 0.000
I21.4 Acute subendocardial myocardial infarction
0.701 0.299 0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.700 0.300 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.700 0.300 0.000
L94 Other localised connective tissue disorders
0.700 0.300 0.000
L93 Lupus erythematosus
0.700 0.300 0.000
L87 Transepidermal elimination disorders
0.700 0.300 0.000
L88 Pyoderma gangrenosum
0.700 0.300 0.000
L86 Keratoderma in diseases classified elsewhere
0.700 0.300 0.000
L83 Acanthosis nigricans
0.700 0.300 0.000
L80 Vitiligo
0.700 0.300 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.699 0.301 0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms
0.698 0.302 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.698 0.302 0.000
I51.6 Cardiovascular disease, unspecified
0.698 0.302 0.000
I51.5 Myocardial degeneration
0.698 0.302 0.000
I51.4 Myocarditis, unspecified
0.698 0.302 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.698 0.302 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.698 0.302 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.698 0.302 0.000
I51.0 Cardiac septal defect, acquired
0.698 0.302 0.000
M86-M90 Other osteopathies
0.698 0.302 0.000
H40.5 Glaucoma secondary to other eye disorders
0.697 0.303 0.000
A80-A89 Viral infections of the central nervous system
0.697 0.303 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.697 0.303 0.000
C01 Malignant neoplasm of base of tongue
0.696 0.303 0.000
F32.9 Depressive episode, unspecified
0.696 0.304 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.695 0.305 0.000
H16 Keratitis
0.695 0.305 0.000
N00-N08 Glomerular diseases
0.695 0.305 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.694 0.306 0.000
Chapter VI Diseases of the nervous system
0.693 0.307 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.692 0.308 0.000
Chapter VIII Diseases of the ear and mastoid process
0.692 0.308 0.000
M80.98 Unspecified osteoporosis with pathological fracture (Other)
0.691 0.309 0.000
M75.4 Impingement syndrome of shoulder
0.689 0.311 0.000
T82.1 Mechanical complication of cardiac electronic device
0.688 0.312 0.000
H33 Retinal detachments and breaks
0.688 0.312 0.000
M15-M19 Arthrosis
0.687 0.313 0.000
I05-I09 Chronic rheumatic heart diseases
0.686 0.314 0.000
I62 Other nontraumatic intracranial haemorrhage
0.686 0.314 0.000
H42 Glaucoma in diseases classified elsewhere
0.686 0.314 0.000
T83.3 Mechanical complication of intra-uterine contraceptive device
0.685 0.315 0.000
Q60-Q64 Congenital malformations of the urinary system
0.684 0.316 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.684 0.316 0.000
N13 Obstructive and reflux uropathy
0.683 0.317 0.000
F38 Other mood [affective] disorders
0.682 0.317 0.000
F34 Persistent mood [affective] disorders
0.682 0.317 0.000
F30 Manic episode
0.682 0.317 0.000
F39 Unspecified mood [affective] disorder
0.682 0.317 0.000
L40-L45 Papulosquamous disorders
0.682 0.317 0.000
Q65 Congenital deformities of hip
0.682 0.318 0.000
F11 Mental and behavioural disorders due to use of opioids
0.682 0.318 0.000
I47.9 Paroxysmal tachycardia, unspecified
0.681 0.319 0.000
I47.0 Reentry ventricular arrhythmia
0.681 0.319 0.000
Y35-Y36 Legal intervention and operations of war
0.681 0.319 0.000
Y10-Y34 Event of undetermined intent
0.681 0.319 0.000
Y00-Y09 Assault
0.681 0.319 0.000
X85-X99 Assault
0.681 0.319 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.681 0.319 0.000
X50-X57 Overexertion, travel and privation
0.681 0.319 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.681 0.319 0.000
X30-X39 Exposure to forces of nature
0.681 0.319 0.000
X10-X19 Contact with heat and hot substances
0.681 0.319 0.000
X00-X09 Exposure to smoke, fire and flames
0.681 0.319 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.681 0.319 0.000
W75-W84 Other accidental threats to breathing
0.681 0.319 0.000
W65-W74 Accidental drowning and submersion
0.681 0.319 0.000
W50-W64 Exposure to animate mechanical forces
0.681 0.319 0.000
V98-V99 Other and unspecified transport accidents
0.681 0.319 0.000
V95-V97 Air and space transport accidents
0.681 0.319 0.000
V90-V94 Water transport accidents
0.681 0.319 0.000
V80-V89 Other land transport accidents
0.681 0.319 0.000
V70-V79 Bus occupant injured in transport accident
0.681 0.319 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.681 0.319 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.681 0.319 0.000
V40-V49 Car occupant injured in transport accident
0.681 0.319 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.681 0.319 0.000
V01-V09 Pedestrian injured in transport accident
0.681 0.319 0.000
C50.8 Overlapping lesion of breast
0.681 0.319 0.000
S08 Traumatic amputation of part of head
0.678 0.321 0.000
S07 Crushing injury of head
0.678 0.321 0.000
S05 Injury of eye and orbit
0.678 0.321 0.000
S04 Injury of cranial nerves
0.678 0.321 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.678 0.321 0.000
S00.3 Superficial injury of nose
0.678 0.322 0.000
F33 Recurrent depressive disorder
0.678 0.322 0.000
N20-N23 Urolithiasis
0.678 0.322 0.000
I61 Intracerebral haemorrhage
0.677 0.323 0.000
H40.1 Primary open-angle glaucoma
0.676 0.324 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.676 0.324 0.000
I45.6 Preexcitation syndrome
0.675 0.325 0.000
H40.8 Other glaucoma
0.675 0.325 0.000
H40.6 Glaucoma secondary to drugs
0.675 0.325 0.000
H40.4 Glaucoma secondary to eye inflammation
0.675 0.325 0.000
H40.3 Glaucoma secondary to eye trauma
0.675 0.325 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.675 0.325 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.675 0.325 0.000
D45 Polycythaemia vera
0.675 0.325 0.000
F45 Somatoform disorders
0.675 0.325 0.000
C53 Malignant neoplasm of cervix uteri
0.674 0.326 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.674 0.326 0.000
F43 Reaction to severe stress, and adjustment disorders
0.674 0.326 0.000
A30-A49 Other bacterial diseases
0.673 0.327 0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere
0.673 0.327 0.000
U80 Agent resistant to penicillin and related antibiotics
0.671 0.329 0.000
N99-N99 Other disorders of the genitourinary system
0.671 0.329 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.671 0.329 0.000
C55 Malignant neoplasm of uterus, part unspecified
0.670 0.330 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.670 0.330 0.000
S09.8 Other specified injuries of head
0.670 0.330 0.000
C54 Malignant neoplasm of corpus uteri
0.669 0.331 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.669 0.331 0.000
Q00-Q07 Congenital malformations of the nervous system
0.669 0.331 0.000
C56 Malignant neoplasm of ovary
0.668 0.332 0.000
S09.9 Unspecified injury of head
0.668 0.332 0.000
E83.1 Disorders of iron metabolism
0.668 0.332 0.000
D46 Myelodysplastic syndromes
0.667 0.333 0.000
F41 Other anxiety disorders
0.667 0.333 0.000
L98.4 Chronic ulcer of skin, not elsewhere classified
0.665 0.335 0.000
D80-D89 Certain disorders involving the immune mechanism
0.664 0.336 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.664 0.336 0.000
Q80-Q89 Other congenital malformations
0.664 0.336 0.000
Q35-Q37 Cleft lip and cleft palate
0.664 0.336 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.664 0.336 0.000
M16 Coxarthrosis [arthrosis of hip]
0.663 0.337 0.000
L98.7 Excessive and redundant skin and subcutaneous tissue
0.663 0.337 0.000
L98.6 Other infiltrative disorders of skin and subcutaneous tissue
0.663 0.337 0.000
L98.5 Mucinosis of skin
0.663 0.337 0.000
L98.3 Eosinophilic cellulitis [Wells]
0.663 0.337 0.000
L98.2 Febrile neutrophilic dermatosis [Sweet]
0.663 0.337 0.000
L98.1 Factitial dermatitis
0.663 0.337 0.000
W00-W19 Falls
0.662 0.338 0.000
E73 Lactose intolerance
0.662 0.338 0.000
I50.0 Congestive heart failure
0.662 0.338 0.000
C50.5 Lower-outer quadrant of breast
0.662 0.338 0.000
I35 Nonrheumatic aortic valve disorders
0.662 0.338 0.000
I25.5 Ischaemic cardiomyopathy
0.661 0.339 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.660 0.339 0.000
I33 Acute and subacute endocarditis
0.660 0.340 0.000
L50-L54 Urticaria and erythema
0.659 0.340 0.000
Q78 Other osteochondrodysplasias
0.659 0.341 0.000
I69 Sequelae of cerebrovascular disease
0.659 0.341 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.658 0.342 0.000
H35 Other retinal disorders
0.658 0.342 0.000
H53-H54 Visual disturbances and blindness
0.657 0.343 0.000
H10-H13 Disorders of conjunctiva
0.657 0.343 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.656 0.344 0.000
T83.0 Mechanical complication of urinary (indwelling) catheter
0.656 0.344 0.000
I31.9 Disease of pericardium, unspecified
0.656 0.344 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.655 0.345 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.655 0.345 0.000
S01 Open wound of head
0.653 0.347 0.000
D06 Carcinoma in situ of cervix uteri
0.653 0.347 0.000
Q50-Q56 Congenital malformations of genital organs
0.652 0.348 0.000
Y52 Agents primarily affecting the cardiovascular system
0.652 0.348 0.000
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract
0.652 0.348 0.000
T93 Sequelae of injuries of lower limb
0.652 0.348 0.000
S00.7 Multiple superficial injuries of head
0.651 0.349 0.000
S00.5 Superficial injury of lip and oral cavity
0.651 0.349 0.000
S00.4 Superficial injury of ear
0.651 0.349 0.000
S00.2 Other superficial injuries of eyelid and periocular area
0.651 0.349 0.000
I78.0 Hereditary haemorrhagic telangiectasia
0.651 0.349 0.000
F23 Acute and transient psychotic disorders
0.650 0.350 0.000
L84 Corns and callosities
0.649 0.351 0.000
F31.8 Other bipolar affective disorders
0.648 0.351 0.000
F31.7 Bipolar affective disorder, currently in remission
0.648 0.351 0.000
F31.6 Bipolar affective disorder, current episode mixed
0.648 0.351 0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms
0.648 0.351 0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms
0.648 0.351 0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression
0.648 0.351 0.000
F31.0 Bipolar affective disorder, current episode hypomanic
0.648 0.351 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.648 0.352 0.000
E27 Other disorders of adrenal gland
0.647 0.353 0.000
Y57 Other and unspecified drugs and medicaments
0.647 0.353 0.000
I42 Cardiomyopathy
0.646 0.354 0.000
B37 Candidiasis
0.646 0.354 0.000
S00.9 Superficial injury of head, part unspecified
0.646 0.354 0.000
I78.1 Naevus, nonneoplastic
0.645 0.355 0.000
L85 Other epidermal thickening
0.644 0.356 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.644 0.356 0.000
C64-C68 Malignant neoplasms of urinary tract
0.644 0.356 0.000
M16.0 Primary coxarthrosis, bilateral
0.643 0.357 0.000
I34.1 Mitral (valve) prolapse
0.642 0.358 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.641 0.358 0.000
M79.8 Other specified soft tissue disorders
0.641 0.358 0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft
0.641 0.359 0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis
0.641 0.359 0.000
T82.4 Mechanical complication of vascular dialysis catheter
0.641 0.359 0.000
T82.3 Mechanical complication of other vascular grafts
0.641 0.359 0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.641 0.359 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.641 0.359 0.000
I73.8 Other specified peripheral vascular diseases
0.641 0.359 0.000
I73.1 Thromboangiitis obliterans [Buerger]
0.641 0.359 0.000
Y40 Systemic antibiotics
0.640 0.360 0.000
L89.0 Stage I decubitus ulcer and pressure area
0.640 0.360 0.000
M84 Disorders of continuity of bone
0.639 0.360 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.639 0.361 0.000
C09 Malignant neoplasm of tonsil
0.639 0.361 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.639 0.361 0.000
F03 Unspecified dementia
0.638 0.361 0.000
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft
0.638 0.362 0.000
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract
0.638 0.362 0.000
T83.2 Mechanical complication of graft of urinary organ
0.638 0.362 0.000
M54 Dorsalgia
0.637 0.363 0.000
N30 Cystitis
0.636 0.364 0.000
Y91 Evidence of alcohol involvement determined by level of intoxication
0.635 0.365 0.000
Y90 Evidence of alcohol involvement determined by blood alcohol level
0.635 0.365 0.000
Y98 Lifestyle-related condition
0.635 0.365 0.000
Y97 Environmental-pollution-related condition
0.635 0.365 0.000
Y96 Work-related condition
0.635 0.365 0.000
I44.6 Other and unspecified fascicular block
0.634 0.366 0.000
I44.5 Left posterior fascicular block
0.634 0.366 0.000
I44.4 Left anterior fascicular block
0.634 0.366 0.000
I44.3 Other and unspecified atrioventricular block
0.634 0.366 0.000
M60-M63 Disorders of muscles
0.634 0.366 0.000
M00-M03 Infectious arthropathies
0.634 0.366 0.000
D70 Agranulocytosis
0.633 0.367 0.000
I45.5 Other specified heart block
0.632 0.368 0.000
T80.2 Infections following infusion, transfusion and therapeutic injection
0.631 0.369 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.631 0.369 0.000
I26 Pulmonary embolism
0.631 0.369 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.631 0.369 0.000
T88.4 Failed or difficult intubation
0.630 0.370 0.000
T92 Sequelae of injuries of upper limb
0.630 0.370 0.000
T78.3 Angioneurotic oedema
0.630 0.370 0.000
E61 Deficiency of other nutrient elements
0.629 0.371 0.000
F48 Other neurotic disorders
0.629 0.371 0.000
F44 Dissociative [conversion] disorders
0.629 0.371 0.000
F42 Obsessive-compulsive disorder
0.629 0.371 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.629 0.371 0.000
Chapter X Diseases of the respiratory system
0.628 0.372 0.000
I47.1 Supraventricular tachycardia
0.628 0.372 0.000
E67 Other hyperalimentation
0.627 0.372 0.000
E68 Sequelae of hyperalimentation
0.627 0.372 0.000
E65 Localised adiposity
0.627 0.372 0.000
M79.6 Pain in limb
0.627 0.373 0.000
E55 Vitamin D deficiency
0.627 0.373 0.000
H47 Other disorders of optic [2nd] nerve and visual pathways
0.627 0.373 0.000
Y44 Agents primarily affecting blood constituents
0.627 0.373 0.000
F10.2 Dependence syndrome
0.627 0.373 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.626 0.373 0.000
B99-B99 Other infectious diseases
0.626 0.374 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.626 0.374 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.626 0.374 0.000
B65-B83 Helminthiases
0.626 0.374 0.000
B50-B64 Protozoal diseases
0.626 0.374 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.626 0.374 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.626 0.374 0.000
A75-A79 Rickettsioses
0.626 0.374 0.000
A70-A74 Other diseases caused by chlamydiae
0.626 0.374 0.000
A65-A69 Other spirochaetal diseases
0.626 0.374 0.000
A20-A28 Certain zoonotic bacterial diseases
0.626 0.374 0.000
A15-A19 Tuberculosis
0.626 0.374 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.625 0.375 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.625 0.375 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.625 0.375 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.625 0.375 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.625 0.375 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.625 0.375 0.000
T36 Poisoning by systemic antibiotics
0.625 0.375 0.000
V10-V19 Pedal cyclist injured in transport accident
0.625 0.375 0.000
E78.5 Hyperlipidaemia, unspecified
0.625 0.375 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.624 0.376 0.000
T81 Complications of procedures, not elsewhere classified
0.624 0.376 0.000
E84 Cystic fibrosis
0.623 0.377 0.000
E79 Disorders of purine and pyrimidine metabolism
0.623 0.377 0.000
E77 Disorders of glycoprotein metabolism
0.623 0.377 0.000
E76 Disorders of glycosaminoglycan metabolism
0.623 0.377 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.623 0.377 0.000
E74 Other disorders of carbohydrate metabolism
0.623 0.377 0.000
E72 Other disorders of amino-acid metabolism
0.623 0.377 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.623 0.377 0.000
E70 Disorders of aromatic amino-acid metabolism
0.623 0.377 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.623 0.377 0.000
I44.1 Atrioventricular block, second degree
0.623 0.377 0.000
M91-M94 Chondropathies
0.623 0.377 0.000
N13.3 Other and unspecified hydronephrosis
0.622 0.378 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.621 0.379 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.621 0.379 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.621 0.379 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.621 0.379 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.621 0.379 0.000
L89.1 Stage II decubitus ulcer
0.620 0.380 0.000
W22 Striking against or struck by other objects
0.620 0.380 0.000
T86.8 Failure and rejection of other transplanted organs and tissues
0.619 0.381 0.000
I77.1 Stricture of artery
0.619 0.381 0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.618 0.382 0.000
I34.8 Other nonrheumatic mitral valve disorders
0.618 0.382 0.000
I34.2 Nonrheumatic mitral (valve) stenosis
0.618 0.382 0.000
C57 Malignant neoplasm of other and unspecified female genital organs
0.617 0.383 0.000
C51 Malignant neoplasm of vulva
0.617 0.383 0.000
C58 Malignant neoplasm of placenta
0.617 0.383 0.000
C52 Malignant neoplasm of vagina
0.617 0.383 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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