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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs117320784
log Bayes Factor = 13.3956
Chromosome 18   position 58,896,482  (GRCh37) Explore rs117320784 on Ensembl!
Variant rs117320784 is part of Cluster X0075

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.999 0.001 0.000
E10-E14 Diabetes mellitus
0.999 0.001 0.000
E11 Non-insulin-dependent diabetes mellitus
0.998 0.002 0.000
M70-M79 Other soft tissue disorders
0.998 0.002 0.000
Chapter IX Diseases of the circulatory system
0.997 0.003 0.000
S00-S09 Injuries to the head
0.995 0.005 0.000
O60-O75 Complications of labour and delivery
0.994 0.006 0.000
M05-M14 Inflammatory polyarthropathies
0.987 0.013 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.987 0.013 0.000
E11.9 Without complications
0.985 0.015 0.000
E70-E90 Metabolic disorders
0.981 0.019 0.000
M06 Other rheumatoid arthritis
0.978 0.022 0.000
S00 Superficial injury of head
0.978 0.022 0.000
M75 Shoulder lesions
0.977 0.023 0.000
M06.9 Rheumatoid arthritis, unspecified
0.973 0.027 0.000
I30-I52 Other forms of heart disease
0.972 0.028 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.968 0.032 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.965 0.035 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.964 0.036 0.000
I20-I25 Ischaemic heart diseases
0.954 0.046 0.000
M75.4 Impingement syndrome of shoulder
0.952 0.048 0.000
E83 Disorders of mineral metabolism
0.950 0.050 0.000
M79.6 Pain in limb
0.949 0.051 0.000
I20 Angina pectoris
0.947 0.053 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.938 0.062 0.000
Chapter XX External causes of morbidity and mortality
0.933 0.067 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.930 0.070 0.000
Chapter VI Diseases of the nervous system
0.930 0.070 0.000
S20-S29 Injuries to the thorax
0.928 0.072 0.000
I20.0 Unstable angina
0.927 0.073 0.000
S00.8 Superficial injury of other parts of head
0.926 0.074 0.000
S50-S59 Injuries to the elbow and forearm
0.920 0.080 0.000
S90-S99 Injuries to the ankle and foot
0.920 0.080 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.907 0.093 0.000
S40-S49 Injuries to the shoulder and upper arm
0.904 0.096 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.899 0.101 0.000
E11.3 With ophthalmic complications
0.893 0.107 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.892 0.108 0.000
O68.1 Labour and delivery complicated by meconium in amniotic fluid
0.891 0.109 0.000
I42 Cardiomyopathy
0.886 0.114 0.000
I20.9 Angina pectoris, unspecified
0.885 0.115 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.882 0.118 0.000
S02 Fracture of skull and facial bones
0.882 0.118 0.000
M79.66 Pain in limb (Lower leg)
0.881 0.119 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.881 0.119 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.878 0.122 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.877 0.123 0.000
E11.5 With peripheral circulatory complications
0.874 0.126 0.000
E10 Insulin-dependent diabetes mellitus
0.872 0.128 0.000
I60-I69 Cerebrovascular diseases
0.870 0.130 0.000
G90-G99 Other disorders of the nervous system
0.869 0.131 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.868 0.132 0.000
S00.9 Superficial injury of head, part unspecified
0.864 0.136 0.000
M75.5 Bursitis of shoulder
0.860 0.140 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.858 0.142 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.856 0.144 0.000
E83.5 Disorders of calcium metabolism
0.855 0.145 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.851 0.149 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.845 0.155 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.843 0.157 0.000
S92 Fracture of foot, except ankle
0.840 0.160 0.000
M20-M25 Other joint disorders
0.839 0.161 0.000
E11.4 With neurological complications
0.837 0.163 0.000
E11.2 With renal complications
0.832 0.168 0.000
M91-M94 Chondropathies
0.831 0.169 0.000
S51 Open wound of forearm
0.830 0.170 0.000
M79.62 Pain in limb (Upper arm)
0.827 0.173 0.000
O00-O08 Pregnancy with abortive outcome
0.821 0.179 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.820 0.180 0.000
R47-R49 Symptoms and signs involving speech and voice
0.820 0.180 0.000
I44 Atrioventricular and left bundle-branch block
0.819 0.181 0.000
O68.9 Labour and delivery complicated by foetal stress, unspecified
0.818 0.182 0.000
R00 Abnormalities of heart beat
0.818 0.182 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.817 0.183 0.000
Chapter VIII Diseases of the ear and mastoid process
0.817 0.183 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.815 0.185 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.815 0.185 0.000
O63 Long labour
0.815 0.185 0.000
I45 Other conduction disorders
0.814 0.186 0.000
S05 Injury of eye and orbit
0.813 0.187 0.000
M79.7 Fibromyalgia
0.813 0.187 0.000
I35 Nonrheumatic aortic valve disorders
0.813 0.187 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.811 0.189 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.808 0.192 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.807 0.193 0.000
Y40 Systemic antibiotics
0.807 0.193 0.000
M79.69 Pain in limb (Site unspecified)
0.804 0.196 0.000
S06 Intracranial injury
0.803 0.197 0.000
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium
0.803 0.197 0.000
I50 Heart failure
0.802 0.198 0.000
O62 Abnormalities of forces of labour
0.801 0.199 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.801 0.199 0.000
I95 Hypotension
0.800 0.200 0.000
I20.1 Angina pectoris with documented spasm
0.799 0.201 0.000
E83.4 Disorders of magnesium metabolism
0.799 0.201 0.000
I49 Other cardiac arrhythmias
0.795 0.205 0.000
O72 Postpartum haemorrhage
0.793 0.207 0.000
O66 Other obstructed labour
0.792 0.208 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.791 0.209 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.791 0.209 0.000
M71 Other bursopathies
0.791 0.209 0.000
S40 Superficial injury of shoulder and upper arm
0.790 0.210 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.790 0.210 0.000
E86 Volume depletion
0.790 0.210 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.790 0.210 0.000
Chapter I Certain infectious and parasitic diseases
0.789 0.211 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.789 0.211 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.784 0.216 0.000
O71 Other obstetric trauma
0.784 0.216 0.000
T39.0 Salicylates
0.784 0.216 0.000
M80-M85 Disorders of bone density and structure
0.783 0.217 0.000
M23 Internal derangement of knee
0.780 0.220 0.000
M65-M68 Disorders of synovium and tendon
0.780 0.220 0.000
R04 Haemorrhage from respiratory passages
0.780 0.220 0.000
G93 Other disorders of brain
0.779 0.221 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.779 0.221 0.000
E89.0 Postprocedural hypothyroidism
0.779 0.221 0.000
O68.8 Labour and delivery complicated by other evidence of foetal stress
0.779 0.221 0.000
E40-E46 Malnutrition
0.778 0.222 0.000
E83.3 Disorders of phosphorus metabolism
0.778 0.222 0.000
E83.1 Disorders of iron metabolism
0.778 0.222 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.776 0.224 0.000
I42.9 Cardiomyopathy, unspecified
0.774 0.226 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.773 0.227 0.000
R93.3 Abnormal findings on diagnostic imaging of other parts of digestive tract
0.772 0.228 0.000
R41.0 Disorientation, unspecified
0.771 0.229 0.000
O23 Infections of genito-urinary tract in pregnancy
0.770 0.230 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.770 0.230 0.000
M10 Gout
0.769 0.231 0.000
S20 Superficial injury of thorax
0.768 0.232 0.000
S70-S79 Injuries to the hip and thigh
0.766 0.234 0.000
I62 Other nontraumatic intracranial haemorrhage
0.765 0.235 0.000
M75.3 Calcific tendinitis of shoulder
0.765 0.235 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.764 0.236 0.000
M75.2 Bicipital tendinitis
0.761 0.239 0.000
I50.0 Congestive heart failure
0.759 0.241 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.758 0.242 0.000
E10.3 With ophthalmic complications
0.755 0.245 0.000
E50-E64 Other nutritional deficiencies
0.754 0.246 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.754 0.246 0.000
M00-M03 Infectious arthropathies
0.754 0.246 0.000
M60-M63 Disorders of muscles
0.754 0.246 0.000
T66-T78 Other and unspecified effects of external causes
0.753 0.247 0.000
I37 Pulmonary valve disorders
0.752 0.248 0.000
O70 Perineal laceration during delivery
0.752 0.248 0.000
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium
0.752 0.248 0.000
T39.1 4-Aminophenol derivatives
0.751 0.249 0.000
S00.0 Superficial injury of scalp
0.751 0.249 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.751 0.249 0.000
I95.1 Orthostatic hypotension
0.751 0.249 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.750 0.250 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.750 0.250 0.000
S51.0 Open wound of elbow
0.750 0.250 0.000
O73 Retained placenta and membranes, without haemorrhage
0.749 0.251 0.000
I49.8 Other specified cardiac arrhythmias
0.749 0.251 0.000
S00.7 Multiple superficial injuries of head
0.749 0.251 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.748 0.252 0.000
I42.0 Dilated cardiomyopathy
0.748 0.252 0.000
I44.0 Atrioventricular block, first degree
0.747 0.253 0.000
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid
0.746 0.254 0.000
D80-D89 Certain disorders involving the immune mechanism
0.745 0.254 0.000
I47 Paroxysmal tachycardia
0.745 0.255 0.000
Chapter XXII Codes for special purposes
0.744 0.256 0.000
M76 Enthesopathies of lower limb, excluding foot
0.743 0.257 0.000
I05-I09 Chronic rheumatic heart diseases
0.741 0.259 0.000
S00.1 Contusion of eyelid and periocular area
0.741 0.259 0.000
I33 Acute and subacute endocarditis
0.740 0.260 0.000
M79.61 Pain in limb (Shoulder region)
0.737 0.263 0.000
I45.1 Other and unspecified right bundle-branch block
0.735 0.265 0.000
I51 Complications and ill-defined descriptions of heart disease
0.734 0.266 0.000
G95 Other diseases of spinal cord
0.734 0.266 0.000
I60 Subarachnoid haemorrhage
0.732 0.268 0.000
S92.0 Fracture of calcaneus
0.731 0.269 0.000
T79-T79 Certain early complications of trauma
0.730 0.270 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.729 0.271 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.728 0.272 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.728 0.272 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.727 0.273 0.000
R09.1 Pleurisy
0.727 0.273 0.000
M79.65 Pain in limb (Pelvic region and thigh)
0.726 0.274 0.000
I24 Other acute ischaemic heart diseases
0.726 0.274 0.000
G20-G26 Extrapyramidal and movement disorders
0.724 0.276 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.721 0.279 0.000
B95-B98 Bacterial, viral and other infectious agents
0.721 0.279 0.000
S99 Other and unspecified injuries of ankle and foot
0.720 0.280 0.000
O63.1 Prolonged second stage (of labour)
0.719 0.281 0.000
S29 Other and unspecified injuries of thorax
0.718 0.282 0.000
D60-D64 Aplastic and other anaemias
0.718 0.282 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S10-S19 Injuries to the neck
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
O85-O92 Complications predominantly related to the puerperium
0.716 0.283 0.000
E88 Other metabolic disorders
0.716 0.283 0.000
E13 Other specified diabetes mellitus
0.716 0.284 0.000
E12 Malnutrition-related diabetes mellitus
0.716 0.284 0.000
E11.8 With unspecified complications
0.716 0.284 0.000
E11.7 With multiple complications
0.716 0.284 0.000
E11.6 With other specified complications
0.716 0.284 0.000
E11.1 With ketoacidosis
0.716 0.284 0.000
E11.0 With coma
0.716 0.284 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.716 0.284 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.715 0.285 0.000
W50-W64 Exposure to animate mechanical forces
0.715 0.285 0.000
I00-I02 Acute rheumatic fever
0.715 0.285 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.714 0.286 0.000
S08 Traumatic amputation of part of head
0.713 0.287 0.000
S07 Crushing injury of head
0.713 0.287 0.000
S04 Injury of cranial nerves
0.713 0.287 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.713 0.287 0.000
M11 Other crystal arthropathies
0.713 0.287 0.000
X50-X57 Overexertion, travel and privation
0.713 0.287 0.000
O74 Complications of anaesthesia during labour and delivery
0.713 0.287 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.713 0.287 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.713 0.287 0.000
O61 Failed induction of labour
0.713 0.287 0.000
O60 Preterm delivery
0.713 0.287 0.000
S52 Fracture of forearm
0.712 0.287 0.000
M79.64 Pain in limb (Hand)
0.712 0.287 0.000
S50 Superficial injury of forearm
0.712 0.288 0.000
S09 Other and unspecified injuries of head
0.708 0.291 0.000
I10-I15 Hypertensive diseases
0.708 0.292 0.000
M14 Arthropathies in other diseases classified elsewhere
0.707 0.292 0.000
M12 Other specific arthropathies
0.707 0.292 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.707 0.292 0.000
M08 Juvenile arthritis
0.707 0.292 0.000
E10.4 With neurological complications
0.707 0.293 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.707 0.293 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.707 0.293 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.707 0.293 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.707 0.293 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.707 0.293 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.707 0.293 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.707 0.293 0.000
T36 Poisoning by systemic antibiotics
0.707 0.293 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.707 0.293 0.000
R93.8 Abnormal findings on diagnostic imaging of other specified body structures
0.706 0.294 0.000
V40-V49 Car occupant injured in transport accident
0.706 0.294 0.000
Chapter II Neoplasms
0.706 0.294 0.000
V80-V89 Other land transport accidents
0.704 0.296 0.000
E85 Amyloidosis
0.704 0.296 0.000
E84 Cystic fibrosis
0.704 0.296 0.000
E79 Disorders of purine and pyrimidine metabolism
0.704 0.296 0.000
E77 Disorders of glycoprotein metabolism
0.704 0.296 0.000
E76 Disorders of glycosaminoglycan metabolism
0.704 0.296 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.704 0.296 0.000
E74 Other disorders of carbohydrate metabolism
0.704 0.296 0.000
E73 Lactose intolerance
0.704 0.296 0.000
E72 Other disorders of amino-acid metabolism
0.704 0.296 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.704 0.296 0.000
E70 Disorders of aromatic amino-acid metabolism
0.704 0.296 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.704 0.296 0.000
E78.0 Pure hypercholesterolaemia
0.702 0.298 0.000
M79.79 Fibromyalgia (Site unspecified)
0.702 0.298 0.000
R49 Voice disturbances
0.702 0.298 0.000
M06.8 Other specified rheumatoid arthritis
0.701 0.299 0.000
M06.4 Inflammatory polyarthropathy
0.701 0.299 0.000
M06.3 Rheumatoid nodule
0.701 0.299 0.000
M06.2 Rheumatoid bursitis
0.701 0.299 0.000
M06.1 Adult-onset Still's disease
0.701 0.299 0.000
E20-E35 Disorders of other endocrine glands
0.701 0.299 0.000
S00.5 Superficial injury of lip and oral cavity
0.701 0.299 0.000
S00.4 Superficial injury of ear
0.701 0.299 0.000
S00.3 Superficial injury of nose
0.701 0.299 0.000
S00.2 Other superficial injuries of eyelid and periocular area
0.701 0.299 0.000
M75.8 Other shoulder lesions
0.700 0.300 0.000
M75.9 Shoulder lesion, unspecified
0.700 0.300 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.699 0.301 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.698 0.301 0.000
S27 Injury of other and unspecified intrathoracic organs
0.698 0.302 0.000
S02.1 Fracture of base of skull
0.698 0.302 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.698 0.302 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.698 0.302 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.698 0.302 0.000
M05 Seropositive rheumatoid arthritis
0.698 0.302 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.698 0.302 0.000
I52 Other heart disorders in diseases classified elsewhere
0.697 0.303 0.000
I48 Atrial fibrillation and flutter
0.697 0.303 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.697 0.303 0.000
I41 Myocarditis in diseases classified elsewhere
0.697 0.303 0.000
I40 Acute myocarditis
0.697 0.303 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.697 0.303 0.000
I36 Nonrheumatic tricuspid valve disorders
0.697 0.303 0.000
I32 Pericarditis in diseases classified elsewhere
0.697 0.303 0.000
T43.2 Other and unspecified antidepressants
0.696 0.304 0.000
R00.0 Tachycardia, unspecified
0.696 0.304 0.000
S02.2 Fracture of nasal bones
0.695 0.305 0.000
Y52 Agents primarily affecting the cardiovascular system
0.695 0.305 0.000
D50-D53 Nutritional anaemias
0.695 0.305 0.000
S02.4 Fracture of malar and maxillary bones
0.694 0.306 0.000
M79.9 Soft tissue disorder, unspecified
0.694 0.306 0.000
M79.5 Residual foreign body in soft tissue
0.694 0.306 0.000
M79.3 Panniculitis, unspecified
0.694 0.306 0.000
M79.2 Neuralgia and neuritis, unspecified
0.694 0.306 0.000
M79.1 Myalgia
0.694 0.306 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.693 0.307 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.693 0.307 0.000
T45.0 Antiallergic and antiemetic drugs
0.693 0.307 0.000
O68.3 Labour and delivery complicated by biochemical evidence of foetal stress
0.691 0.309 0.000
E89.3 Postprocedural hypopituitarism
0.691 0.309 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.690 0.310 0.000
M40-M43 Deforming dorsopathies
0.690 0.310 0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.688 0.312 0.000
T91 Sequelae of injuries of neck and trunk
0.688 0.312 0.000
R04.2 Haemoptysis
0.688 0.312 0.000
Y44 Agents primarily affecting blood constituents
0.687 0.313 0.000
H90-H95 Other disorders of ear
0.686 0.314 0.000
Y40.0 Penicillins
0.686 0.314 0.000
M13 Other arthritis
0.685 0.315 0.000
O68.0 Labour and delivery complicated by foetal heart rate anomaly
0.685 0.315 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.684 0.316 0.000
S92.3 Fracture of metatarsal bone
0.684 0.316 0.000
I23 Certain current complications following acute myocardial infarction
0.684 0.316 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.684 0.316 0.000
S05.0 Injury of conjunctiva and corneal abrasion without mention of foreign body
0.683 0.317 0.000
R05 Cough
0.683 0.317 0.000
E83.9 Disorder of mineral metabolism, unspecified
0.681 0.319 0.000
E83.8 Other disorders of mineral metabolism
0.681 0.319 0.000
E83.2 Disorders of zinc metabolism
0.681 0.319 0.000
E83.0 Disorders of copper metabolism
0.681 0.319 0.000
G70-G73 Diseases of myoneural junction and muscle
0.681 0.319 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.681 0.319 0.000
M79.68 Pain in limb (Other)
0.680 0.320 0.000
W20-W49 Exposure to inanimate mechanical forces
0.680 0.320 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.678 0.322 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.678 0.322 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.677 0.323 0.000
S01 Open wound of head
0.676 0.324 0.000
M22 Disorders of patella
0.676 0.324 0.000
R41.3 Other amnesia
0.675 0.325 0.000
M23.8 Other internal derangements of knee
0.675 0.325 0.000
Y40.1 Cefalosporins and other -lactam antibiotics
0.675 0.325 0.000
I69 Sequelae of cerebrovascular disease
0.673 0.327 0.000
I46 Cardiac arrest
0.672 0.328 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.672 0.328 0.000
M79.63 Pain in limb (Forearm)
0.671 0.329 0.000
I67 Other cerebrovascular diseases
0.671 0.329 0.000
O02 Other abnormal products of conception
0.671 0.329 0.000
R00.1 Bradycardia, unspecified
0.671 0.329 0.000
S90 Superficial injury of ankle and foot
0.670 0.329 0.000
G96 Other disorders of central nervous system
0.670 0.330 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.669 0.331 0.000
Y35-Y36 Legal intervention and operations of war
0.669 0.331 0.000
Y10-Y34 Event of undetermined intent
0.669 0.331 0.000
Y00-Y09 Assault
0.669 0.331 0.000
X85-X99 Assault
0.669 0.331 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.669 0.331 0.000
X30-X39 Exposure to forces of nature
0.669 0.331 0.000
X20-X29 Contact with venomous animals and plants
0.669 0.331 0.000
X10-X19 Contact with heat and hot substances
0.669 0.331 0.000
X00-X09 Exposure to smoke, fire and flames
0.669 0.331 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.669 0.331 0.000
W75-W84 Other accidental threats to breathing
0.669 0.331 0.000
W65-W74 Accidental drowning and submersion
0.669 0.331 0.000
V98-V99 Other and unspecified transport accidents
0.669 0.331 0.000
V95-V97 Air and space transport accidents
0.669 0.331 0.000
V90-V94 Water transport accidents
0.669 0.331 0.000
V70-V79 Bus occupant injured in transport accident
0.669 0.331 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.669 0.331 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.669 0.331 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.669 0.331 0.000
V01-V09 Pedestrian injured in transport accident
0.669 0.331 0.000
M93 Other osteochondropathies
0.668 0.332 0.000
T40.2 Other opioids
0.667 0.333 0.000
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.667 0.333 0.000
O97 Death from sequelae of direct obstetric causes
0.667 0.333 0.000
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery
0.667 0.333 0.000
O95 Obstetric death of unspecified cause
0.667 0.333 0.000
O94 Sequelae of complication of pregnancy, childbirth and the puerperium
0.667 0.333 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.666 0.334 0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.666 0.334 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.665 0.334 0.000
S26 Injury of heart
0.665 0.334 0.000
S25 Injury of blood vessels of thorax
0.665 0.334 0.000
S24 Injury of nerves and spinal cord at thorax level
0.665 0.334 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.665 0.334 0.000
S21 Open wound of thorax
0.665 0.334 0.000
M77 Other enthesopathies
0.665 0.335 0.000
R09.3 Abnormal sputum
0.665 0.335 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.664 0.336 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.663 0.336 0.000
V10-V19 Pedal cyclist injured in transport accident
0.662 0.338 0.000
M24 Other specific joint derangements
0.661 0.338 0.000
R93.1 Abnormal findings on diagnostic imaging of heart and coronary circulation
0.661 0.339 0.000
O03 Spontaneous abortion
0.661 0.339 0.000
S02.6 Fracture of mandible
0.661 0.339 0.000
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium
0.660 0.340 0.000
M30 Polyarteritis nodosa and related conditions
0.660 0.340 0.000
S59 Other and unspecified injuries of forearm
0.660 0.340 0.000
S58 Traumatic amputation of forearm
0.660 0.340 0.000
S57 Crushing injury of forearm
0.660 0.340 0.000
S56 Injury of muscle and tendon at forearm level
0.660 0.340 0.000
S55 Injury of blood vessels at forearm level
0.660 0.340 0.000
S54 Injury of nerves at forearm level
0.660 0.340 0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow
0.660 0.340 0.000
S98 Traumatic amputation of ankle and foot
0.659 0.340 0.000
S97 Crushing injury of ankle and foot
0.659 0.340 0.000
S96 Injury of muscle and tendon at ankle and foot level
0.659 0.340 0.000
S95 Injury of blood vessels at ankle and foot level
0.659 0.340 0.000
S94 Injury of nerves at ankle and foot level
0.659 0.340 0.000
I35.8 Other aortic valve disorders
0.659 0.341 0.000
M45-M49 Spondylopathies
0.659 0.341 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.659 0.341 0.000
I30 Acute pericarditis
0.658 0.342 0.000
O23.9 Other and unspecified genito-urinary tract infection in pregnancy
0.658 0.342 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.658 0.342 0.000
M67 Other disorders of synovium and tendon
0.658 0.342 0.000
S40.9 Superficial injury of shoulder and upper arm, unspecified
0.658 0.342 0.000
G91 Hydrocephalus
0.657 0.343 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.657 0.343 0.000
M79.67 Pain in limb (Ankle and foot)
0.656 0.344 0.000
M94 Other disorders of cartilage
0.656 0.344 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.654 0.346 0.000
S92.00 Fracture of calcaneus (closed)
0.654 0.346 0.000
S51.8 Open wound of other parts of forearm
0.653 0.347 0.000
R47 Speech disturbances, not elsewhere classified
0.653 0.347 0.000
G30-G32 Other degenerative diseases of the nervous system
0.653 0.347 0.000
I22 Subsequent myocardial infarction
0.653 0.347 0.000
O72.1 Other immediate postpartum haemorrhage
0.653 0.347 0.000
S40.8 Other superficial injuries of shoulder and upper arm
0.652 0.348 0.000
S22.3 Fracture of rib
0.652 0.348 0.000
M72 Fibroblastic disorders
0.651 0.349 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.651 0.349 0.000
O24 Diabetes mellitus in pregnancy
0.650 0.349 0.000
R26 Abnormalities of gait and mobility
0.651 0.349 0.000
M84 Disorders of continuity of bone
0.650 0.349 0.000
Y59 Other and unspecified vaccines and biological substances
0.650 0.350 0.000
Y58 Bacterial vaccines
0.650 0.350 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.650 0.350 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.650 0.350 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.650 0.350 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.650 0.350 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.650 0.350 0.000
Y48 Anaesthetics and therapeutic gases
0.650 0.350 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.650 0.350 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.650 0.350 0.000
I35.1 Aortic (valve) insufficiency
0.650 0.350 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.649 0.351 0.000
S48 Traumatic amputation of shoulder and upper arm
0.648 0.352 0.000
S45 Injury of blood vessels at shoulder and upper arm level
0.648 0.352 0.000
S44 Injury of nerves at shoulder and upper arm level
0.648 0.352 0.000
S41 Open wound of shoulder and upper arm
0.648 0.352 0.000
S47 Crushing injury of shoulder and upper arm
0.648 0.352 0.000
S22.2 Fracture of sternum
0.648 0.352 0.000
H80-H83 Diseases of inner ear
0.648 0.352 0.000
T90 Sequelae of injuries of head
0.648 0.352 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.648 0.352 0.000
S02.3 Fracture of orbital floor
0.648 0.352 0.000
S92.2 Fracture of other tarsal bone(s)
0.648 0.352 0.000
O66.5 Failed application of vacuum extractor and forceps, unspecified
0.647 0.353 0.000
M31 Other necrotising vasculopathies
0.646 0.354 0.000
E10.5 With peripheral circulatory complications
0.644 0.355 0.000
G93.8 Other specified disorders of brain
0.643 0.357 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.643 0.357 0.000
M71.2 Synovial cyst of popliteal space [Baker]
0.642 0.358 0.000
S02.0 Fracture of vault of skull
0.641 0.359 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.641 0.359 0.000
I95.8 Other hypotension
0.640 0.360 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.640 0.360 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.640 0.360 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.640 0.360 0.000
T39.4 Antirheumatics, not elsewhere classified
0.640 0.360 0.000
T39.2 Pyrazolone derivatives
0.640 0.360 0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified
0.639 0.361 0.000
M21 Other acquired deformities of limbs
0.638 0.362 0.000
T92 Sequelae of injuries of upper limb
0.638 0.362 0.000
T93 Sequelae of injuries of lower limb
0.638 0.362 0.000
Y46.2 Hydantoin derivatives
0.638 0.362 0.000
M86-M90 Other osteopathies
0.637 0.362 0.000
S42 Fracture of shoulder and upper arm
0.637 0.363 0.000
Y57 Other and unspecified drugs and medicaments
0.637 0.363 0.000
O23.4 Unspecified infection of urinary tract in pregnancy
0.637 0.363 0.000
S02.5 Fracture of tooth
0.636 0.364 0.000
R02 Gangrene, not elsewhere classified
0.636 0.364 0.000
I42.8 Other cardiomyopathies
0.635 0.365 0.000
I42.7 Cardiomyopathy due to drugs and other external agents
0.635 0.365 0.000
I42.6 Alcoholic cardiomyopathy
0.635 0.365 0.000
I42.5 Other restrictive cardiomyopathy
0.635 0.365 0.000
I42.4 Endocardial fibroelastosis
0.635 0.365 0.000
I42.3 Endomyocardial (eosinophilic) disease
0.635 0.365 0.000
I42.2 Other hypertrophic cardiomyopathy
0.635 0.365 0.000
I42.1 Obstructive hypertrophic cardiomyopathy
0.635 0.365 0.000
S06.5 Traumatic subdural haemorrhage
0.635 0.365 0.000
R45 Symptoms and signs involving emotional state
0.635 0.365 0.000
R00.8 Other and unspecified abnormalities of heart beat
0.634 0.366 0.000
M07 Psoriatic and enteropathic arthropathies
0.634 0.366 0.000
M06.0 Seronegative rheumatoid arthritis
0.634 0.366 0.000
M23.5 Chronic instability of knee
0.633 0.367 0.000
O71.4 Obstetric high vaginal laceration alone
0.633 0.367 0.000
H92 Otalgia and effusion of ear
0.633 0.367 0.000
S02.9 Fracture of skull and facial bones, part unspecified
0.632 0.368 0.000
S02.8 Fractures of other skull and facial bones
0.632 0.368 0.000
S02.7 Multiple fractures involving skull and facial bones
0.632 0.368 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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