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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs117336177
log Bayes Factor = 15.6541
Chromosome 8   position 66,701,846  (GRCh37) Explore rs117336177 on Ensembl!
Variant rs117336177 is part of Cluster X0075

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter VII Diseases of the eye and adnexa
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.996 0.004 0.000
H25-H28 Disorders of lens
0.995 0.005 0.000
R50-R69 General symptoms and signs
0.994 0.006 0.000
I30-I52 Other forms of heart disease
0.993 0.007 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.992 0.008 0.000
M45-M49 Spondylopathies
0.992 0.008 0.000
R55 Syncope and collapse
0.991 0.009 0.000
H25 Senile cataract
0.990 0.010 0.000
Chapter I Certain infectious and parasitic diseases
0.983 0.017 0.000
Chapter XXI Factors influencing health status and contact with health services
0.981 0.019 0.000
Z13 Special screening examination for other diseases and disorders
0.979 0.021 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.979 0.021 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.978 0.022 0.000
M47 Spondylosis
0.978 0.022 0.000
I47 Paroxysmal tachycardia
0.978 0.022 0.000
Z13.9 Special screening examination, unspecified
0.975 0.025 0.000
Chapter X Diseases of the respiratory system
0.973 0.027 0.000
E70-E90 Metabolic disorders
0.971 0.029 0.000
B95-B98 Bacterial, viral and other infectious agents
0.954 0.046 0.000
H25.0 Senile incipient cataract
0.950 0.050 0.000
Z13.6 Special screening examination for cardiovascular disorders
0.947 0.053 0.000
E10-E14 Diabetes mellitus
0.943 0.057 0.000
Chapter II Neoplasms
0.940 0.060 0.000
J20-J22 Other acute lower respiratory infections
0.939 0.061 0.000
H25.9 Senile cataract, unspecified
0.935 0.065 0.000
E86 Volume depletion
0.933 0.067 0.000
M47.8 Other spondylosis
0.929 0.071 0.000
M05-M14 Inflammatory polyarthropathies
0.928 0.072 0.000
E11 Non-insulin-dependent diabetes mellitus
0.927 0.073 0.000
M20-M25 Other joint disorders
0.926 0.074 0.000
Chapter XX External causes of morbidity and mortality
0.926 0.074 0.000
I47.2 Ventricular tachycardia
0.922 0.078 0.000
I47.1 Supraventricular tachycardia
0.917 0.083 0.000
H30-H36 Disorders of choroid and retina
0.916 0.084 0.000
J22 Unspecified acute lower respiratory infection
0.916 0.084 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.914 0.086 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.913 0.087 0.000
E11.9 Without complications
0.912 0.088 0.000
M47.9 Spondylosis, unspecified
0.911 0.089 0.000
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms
0.908 0.092 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.907 0.093 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.903 0.097 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.903 0.097 0.000
I51 Complications and ill-defined descriptions of heart disease
0.895 0.105 0.000
J30-J39 Other diseases of upper respiratory tract
0.892 0.108 0.000
M80-M85 Disorders of bone density and structure
0.890 0.110 0.000
R53 Malaise and fatigue
0.887 0.113 0.000
E78.5 Hyperlipidaemia, unspecified
0.886 0.114 0.000
I60-I69 Cerebrovascular diseases
0.885 0.115 0.000
R63 Symptoms and signs concerning food and fluid intake
0.883 0.117 0.000
H25.8 Other senile cataract
0.881 0.119 0.000
H33 Retinal detachments and breaks
0.878 0.122 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.876 0.124 0.000
M40-M43 Deforming dorsopathies
0.875 0.125 0.000
M47.97 Spondylosis, unspecified (Lumbosacral region)
0.875 0.125 0.000
I42 Cardiomyopathy
0.873 0.127 0.000
M06 Other rheumatoid arthritis
0.873 0.127 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.873 0.127 0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal
0.872 0.128 0.000
M48 Other spondylopathies
0.871 0.129 0.000
R68 Other general symptoms and signs
0.871 0.129 0.000
D10-D36 Benign neoplasms
0.870 0.130 0.000
R47-R49 Symptoms and signs involving speech and voice
0.870 0.130 0.000
M47.86 Other spondylosis (Lumbar region)
0.867 0.133 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.864 0.136 0.000
H55-H59 Other disorders of eye and adnexa
0.863 0.137 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.863 0.137 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.859 0.141 0.000
A30-A49 Other bacterial diseases
0.858 0.142 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.857 0.143 0.000
Chapter XXII Codes for special purposes
0.851 0.148 0.000
C50-C50 Malignant neoplasm of breast
0.847 0.153 0.000
S00-S09 Injuries to the head
0.847 0.153 0.000
R61 Hyperhidrosis
0.846 0.154 0.000
I44 Atrioventricular and left bundle-branch block
0.840 0.160 0.000
R54 Senility
0.837 0.163 0.000
D12.4 Descending colon
0.837 0.163 0.000
M70-M79 Other soft tissue disorders
0.837 0.163 0.000
I05-I09 Chronic rheumatic heart diseases
0.837 0.163 0.000
I20-I25 Ischaemic heart diseases
0.836 0.164 0.000
M65-M68 Disorders of synovium and tendon
0.835 0.165 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.835 0.165 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.833 0.167 0.000
M06.9 Rheumatoid arthritis, unspecified
0.829 0.171 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.826 0.174 0.000
J32 Chronic sinusitis
0.826 0.174 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.825 0.175 0.000
Chapter VI Diseases of the nervous system
0.823 0.177 0.000
M50-M54 Other dorsopathies
0.823 0.177 0.000
D12.3 Transverse colon
0.822 0.178 0.000
M47.82 Other spondylosis (Cervical region)
0.820 0.180 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.819 0.181 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.818 0.182 0.000
S70-S79 Injuries to the hip and thigh
0.816 0.184 0.000
E11.2 With renal complications
0.814 0.186 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.812 0.188 0.000
W20-W49 Exposure to inanimate mechanical forces
0.810 0.190 0.000
Z09.9 Follow-up examination after unspecified treatment for other conditions
0.806 0.194 0.000
I80 Phlebitis and thrombophlebitis
0.806 0.194 0.000
S02 Fracture of skull and facial bones
0.803 0.197 0.000
H40-H42 Glaucoma
0.802 0.198 0.000
B25-B34 Other viral diseases
0.802 0.198 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.800 0.199 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.799 0.201 0.000
J95-J99 Other diseases of the respiratory system
0.799 0.201 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.799 0.201 0.000
H27 Other disorders of lens
0.793 0.207 0.000
I50 Heart failure
0.790 0.210 0.000
D12.2 Ascending colon
0.790 0.210 0.000
R63.4 Abnormal weight loss
0.789 0.211 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.789 0.211 0.000
H10-H13 Disorders of conjunctiva
0.789 0.211 0.000
D00-D09 In situ neoplasms
0.788 0.212 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.786 0.214 0.000
S90-S99 Injuries to the ankle and foot
0.785 0.215 0.000
D12.5 Sigmoid colon
0.785 0.215 0.000
D45 Polycythaemia vera
0.785 0.215 0.000
M48.0 Spinal stenosis
0.785 0.215 0.000
H33.0 Retinal detachment with retinal break
0.784 0.216 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.783 0.217 0.000
M24 Other specific joint derangements
0.782 0.218 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.782 0.218 0.000
C50 Malignant neoplasm of breast
0.781 0.219 0.000
E50-E64 Other nutritional deficiencies
0.778 0.222 0.000
Z13.0 Special screening examination for diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.778 0.222 0.000
R04 Haemorrhage from respiratory passages
0.777 0.223 0.000
I44.7 Left bundle-branch block, unspecified
0.774 0.226 0.000
M31 Other necrotising vasculopathies
0.774 0.226 0.000
B15-B19 Viral hepatitis
0.773 0.227 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.771 0.229 0.000
S60-S69 Injuries to the wrist and hand
0.771 0.229 0.000
H33.2 Serous retinal detachment
0.771 0.229 0.000
R06 Abnormalities of breathing
0.771 0.229 0.000
I60 Subarachnoid haemorrhage
0.769 0.231 0.000
M47.1 Other spondylosis with myelopathy
0.767 0.233 0.000
D75 Other diseases of blood and blood-forming organs
0.767 0.233 0.000
E40-E46 Malnutrition
0.767 0.233 0.000
I22 Subsequent myocardial infarction
0.765 0.235 0.000
H43-H45 Disorders of vitreous body and globe
0.765 0.235 0.000
M54 Dorsalgia
0.764 0.236 0.000
I71 Aortic aneurysm and dissection
0.763 0.236 0.000
M91-M94 Chondropathies
0.762 0.238 0.000
R41.3 Other amnesia
0.761 0.239 0.000
J38.3 Other diseases of vocal cords
0.759 0.241 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.757 0.243 0.000
M43 Other deforming dorsopathies
0.757 0.243 0.000
E83 Disorders of mineral metabolism
0.756 0.244 0.000
R47 Speech disturbances, not elsewhere classified
0.756 0.244 0.000
I51.4 Myocarditis, unspecified
0.755 0.245 0.000
R05 Cough
0.755 0.245 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.753 0.247 0.000
R68.8 Other specified general symptoms and signs
0.752 0.248 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.751 0.249 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.750 0.250 0.000
R02 Gangrene, not elsewhere classified
0.748 0.252 0.000
R42 Dizziness and giddiness
0.748 0.252 0.000
M47.90 Spondylosis, unspecified (Multiple sites in spine)
0.748 0.252 0.000
Z09.8 Follow-up examination after other treatment for other conditions
0.747 0.253 0.000
E20-E35 Disorders of other endocrine glands
0.746 0.254 0.000
I30 Acute pericarditis
0.744 0.256 0.000
I89.0 Lymphoedema, not elsewhere classified
0.744 0.256 0.000
S02.4 Fracture of malar and maxillary bones
0.744 0.256 0.000
H57 Other disorders of eye and adnexa
0.743 0.257 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.743 0.257 0.000
I51.7 Cardiomegaly
0.742 0.258 0.000
M10 Gout
0.741 0.259 0.000
R61.9 Hyperhidrosis, unspecified
0.740 0.260 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.740 0.260 0.000
I42.2 Other hypertrophic cardiomyopathy
0.740 0.260 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.738 0.262 0.000
I65.2 Occlusion and stenosis of carotid artery
0.737 0.263 0.000
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters
0.737 0.263 0.000
I87 Other disorders of veins
0.737 0.263 0.000
I47.9 Paroxysmal tachycardia, unspecified
0.736 0.264 0.000
M47.87 Other spondylosis (Lumbosacral region)
0.735 0.265 0.000
J32.9 Chronic sinusitis, unspecified
0.735 0.265 0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters
0.734 0.266 0.000
I42.0 Dilated cardiomyopathy
0.733 0.267 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.732 0.268 0.000
M81 Osteoporosis without pathological fracture
0.732 0.268 0.000
I80.1 Phlebitis and thrombophlebitis of femoral vein
0.731 0.269 0.000
T66-T78 Other and unspecified effects of external causes
0.731 0.269 0.000
Z09.0 Follow-up examination after surgery for other conditions
0.731 0.269 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.731 0.269 0.000
Z73 Problems related to life-management difficulty
0.730 0.270 0.000
M45 Ankylosing spondylitis
0.728 0.272 0.000
R52 Pain, not elsewhere classified
0.727 0.273 0.000
M35 Other systemic involvement of connective tissue
0.724 0.276 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.724 0.276 0.000
I86 Varicose veins of other sites
0.723 0.277 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.722 0.277 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.722 0.278 0.000
S50-S59 Injuries to the elbow and forearm
0.722 0.278 0.000
E78.2 Mixed hyperlipidaemia
0.721 0.279 0.000
W22 Striking against or struck by other objects
0.720 0.280 0.000
C50.1 Central portion of breast
0.719 0.281 0.000
E88 Other metabolic disorders
0.718 0.281 0.000
I51.8 Other ill-defined heart diseases
0.718 0.282 0.000
I08 Multiple valve diseases
0.718 0.282 0.000
H26 Other cataract
0.718 0.282 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.718 0.282 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters
0.716 0.284 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.716 0.284 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.715 0.285 0.000
Q50-Q56 Congenital malformations of genital organs
0.715 0.285 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.714 0.285 0.000
Chapter V Mental and behavioural disorders
0.714 0.286 0.000
M46 Other inflammatory spondylopathies
0.714 0.286 0.000
H28 Cataract and other disorders of lens in diseases classified elsewhere
0.713 0.287 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.713 0.287 0.000
R62 Lack of expected normal physiological development
0.713 0.287 0.000
R57 Shock, not elsewhere classified
0.713 0.287 0.000
R64 Cachexia
0.713 0.287 0.000
R58 Haemorrhage, not elsewhere classified
0.713 0.287 0.000
J35 Chronic diseases of tonsils and adenoids
0.712 0.288 0.000
M80 Osteoporosis with pathological fracture
0.712 0.288 0.000
I72 Other aneurysm
0.712 0.288 0.000
D06 Carcinoma in situ of cervix uteri
0.712 0.288 0.000
D35 Benign neoplasm of other and unspecified endocrine glands
0.712 0.288 0.000
I52 Other heart disorders in diseases classified elsewhere
0.712 0.288 0.000
I48 Atrial fibrillation and flutter
0.712 0.288 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.712 0.288 0.000
I41 Myocarditis in diseases classified elsewhere
0.712 0.288 0.000
I40 Acute myocarditis
0.712 0.288 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.712 0.288 0.000
I37 Pulmonary valve disorders
0.712 0.288 0.000
I36 Nonrheumatic tricuspid valve disorders
0.712 0.288 0.000
I32 Pericarditis in diseases classified elsewhere
0.712 0.288 0.000
M05 Seropositive rheumatoid arthritis
0.712 0.288 0.000
M49 Spondylopathies in diseases classified elsewhere
0.711 0.289 0.000
M84 Disorders of continuity of bone
0.711 0.289 0.000
H25.2 Senile cataract, morgagnian type
0.710 0.290 0.000
R26 Abnormalities of gait and mobility
0.709 0.291 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.709 0.291 0.000
M21 Other acquired deformities of limbs
0.708 0.292 0.000
R40 Somnolence, stupor and coma
0.708 0.292 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.707 0.293 0.000
J40-J47 Chronic lower respiratory diseases
0.707 0.293 0.000
C15-C26 Malignant neoplasms of digestive organs
0.706 0.294 0.000
B99-B99 Other infectious diseases
0.705 0.295 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.705 0.295 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.705 0.295 0.000
B65-B83 Helminthiases
0.705 0.295 0.000
B50-B64 Protozoal diseases
0.705 0.295 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.705 0.295 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.705 0.295 0.000
A80-A89 Viral infections of the central nervous system
0.705 0.295 0.000
A75-A79 Rickettsioses
0.705 0.295 0.000
A70-A74 Other diseases caused by chlamydiae
0.705 0.295 0.000
A65-A69 Other spirochaetal diseases
0.705 0.295 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.705 0.295 0.000
A20-A28 Certain zoonotic bacterial diseases
0.705 0.295 0.000
A15-A19 Tuberculosis
0.705 0.295 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.705 0.295 0.000
M20 Acquired deformities of fingers and toes
0.704 0.295 0.000
J32.0 Chronic maxillary sinusitis
0.704 0.296 0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters
0.703 0.297 0.000
I82 Other venous embolism and thrombosis
0.703 0.297 0.000
I69 Sequelae of cerebrovascular disease
0.703 0.297 0.000
Z13.8 Special screening examination for other specified diseases and disorders
0.702 0.298 0.000
Z13.7 Special screening examination for congenital malformations, deformations and chromosomal abnormalities
0.702 0.298 0.000
Z13.5 Special screening examination for eye and ear disorders
0.702 0.298 0.000
Z13.4 Special screening examination for certain developmental disorders in childhood
0.702 0.298 0.000
Z13.3 Special screening examination for mental and behavioural disorders
0.702 0.298 0.000
Z13.2 Special screening examination for nutritional disorders
0.702 0.298 0.000
R01 Cardiac murmurs and other cardiac sounds
0.702 0.298 0.000
D31 Benign neoplasm of eye and adnexa
0.702 0.298 0.000
Z10 Routine general health check-up of defined subpopulation
0.702 0.298 0.000
S02.40 Fracture of malar and maxillary bones (closed)
0.702 0.298 0.000
T33-T35 Frostbite
0.701 0.299 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.701 0.299 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.701 0.299 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.701 0.299 0.000
T00-T07 Injuries involving multiple body regions
0.701 0.299 0.000
S10-S19 Injuries to the neck
0.701 0.299 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.701 0.299 0.000
H33.3 Retinal breaks without detachment
0.701 0.299 0.000
I47.0 Reentry ventricular arrhythmia
0.701 0.299 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.701 0.299 0.000
M23 Internal derangement of knee
0.700 0.300 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.700 0.300 0.000
M25 Other joint disorders, not elsewhere classified
0.698 0.302 0.000
H16 Keratitis
0.697 0.303 0.000
A41 Other septicaemia
0.697 0.303 0.000
E85 Amyloidosis
0.696 0.304 0.000
E84 Cystic fibrosis
0.696 0.304 0.000
E79 Disorders of purine and pyrimidine metabolism
0.696 0.304 0.000
E77 Disorders of glycoprotein metabolism
0.696 0.304 0.000
E76 Disorders of glycosaminoglycan metabolism
0.696 0.304 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.696 0.304 0.000
E74 Other disorders of carbohydrate metabolism
0.696 0.304 0.000
E73 Lactose intolerance
0.696 0.304 0.000
E72 Other disorders of amino-acid metabolism
0.696 0.304 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.696 0.304 0.000
E70 Disorders of aromatic amino-acid metabolism
0.696 0.304 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.696 0.304 0.000
Z04 Examination and observation for other reasons
0.696 0.304 0.000
R47.8 Other and unspecified speech disturbances
0.695 0.305 0.000
C50.0 Nipple and areola
0.694 0.306 0.000
M11 Other crystal arthropathies
0.694 0.306 0.000
C51-C58 Malignant neoplasms of female genital organs
0.694 0.306 0.000
M48.09 Spinal stenosis (Site unspecified)
0.693 0.307 0.000
J38.7 Other diseases of larynx
0.693 0.307 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.692 0.308 0.000
Z45 Adjustment and management of implanted device
0.692 0.308 0.000
M86-M90 Other osteopathies
0.692 0.308 0.000
I49 Other cardiac arrhythmias
0.692 0.308 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.691 0.308 0.000
A49 Bacterial infection of unspecified site
0.691 0.309 0.000
D12.7 Rectosigmoid junction
0.691 0.309 0.000
E78.8 Other disorders of lipoprotein metabolism
0.691 0.309 0.000
M41 Scoliosis
0.689 0.311 0.000
D04 Carcinoma in situ of skin
0.688 0.312 0.000
R68.0 Hypothermia, not associated with low environmental temperature
0.687 0.313 0.000
T79-T79 Certain early complications of trauma
0.687 0.313 0.000
I60.9 Subarachnoid haemorrhage, unspecified
0.687 0.313 0.000
R06.8 Other and unspecified abnormalities of breathing
0.685 0.315 0.000
Y52 Agents primarily affecting the cardiovascular system
0.685 0.315 0.000
M67 Other disorders of synovium and tendon
0.685 0.315 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.685 0.315 0.000
I61 Intracerebral haemorrhage
0.684 0.316 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.684 0.316 0.000
S40-S49 Injuries to the shoulder and upper arm
0.683 0.317 0.000
E65-E68 Obesity and other hyperalimentation
0.682 0.318 0.000
Z02 Examination and encounter for administrative purposes
0.681 0.319 0.000
I78 Diseases of capillaries
0.680 0.320 0.000
I21 Acute myocardial infarction
0.679 0.321 0.000
Chapter XIV Diseases of the genitourinary system
0.679 0.321 0.000
M24.1 Other articular cartilage disorders
0.679 0.321 0.000
I33 Acute and subacute endocarditis
0.679 0.321 0.000
D70 Agranulocytosis
0.678 0.322 0.000
Z45.0 Adjustment and management of cardiac pacemaker
0.678 0.322 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.678 0.322 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.677 0.323 0.000
I46 Cardiac arrest
0.677 0.323 0.000
H18 Other disorders of cornea
0.677 0.323 0.000
D32 Benign neoplasm of meninges
0.677 0.323 0.000
E12 Malnutrition-related diabetes mellitus
0.676 0.324 0.000
I44.3 Other and unspecified atrioventricular block
0.675 0.325 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.674 0.326 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.674 0.326 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.674 0.326 0.000
J21 Acute bronchiolitis
0.673 0.326 0.000
J20 Acute bronchitis
0.673 0.326 0.000
R49 Voice disturbances
0.673 0.327 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.673 0.327 0.000
X60-X84 Intentional self-harm
0.673 0.327 0.000
R59 Enlarged lymph nodes
0.672 0.327 0.000
B34 Viral infection of unspecified site
0.672 0.328 0.000
J60-J70 Lung diseases due to external agents
0.672 0.328 0.000
M43.1 Spondylolisthesis
0.672 0.328 0.000
R63.0 Anorexia
0.671 0.329 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.671 0.329 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.671 0.329 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.670 0.330 0.000
E13 Other specified diabetes mellitus
0.670 0.330 0.000
H21 Other disorders of iris and ciliary body
0.669 0.330 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.669 0.331 0.000
R06.4 Hyperventilation
0.668 0.332 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.668 0.332 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.668 0.332 0.000
M47.2 Other spondylosis with radiculopathy
0.667 0.333 0.000
Z41 Procedures for purposes other than remedying health state
0.667 0.333 0.000
H35 Other retinal disorders
0.667 0.333 0.000
M47.88 Other spondylosis (Sacral and sacrococcygeal region)
0.666 0.334 0.000
M47.85 Other spondylosis (Thoracolumbar region)
0.666 0.334 0.000
M47.84 Other spondylosis (Thoracic region)
0.666 0.334 0.000
M47.83 Other spondylosis (Cervicothoracic region)
0.666 0.334 0.000
M47.81 Other spondylosis (Occipito-atlanto-axial region)
0.666 0.334 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.666 0.334 0.000
H55 Nystagmus and other irregular eye movements
0.666 0.334 0.000
M14 Arthropathies in other diseases classified elsewhere
0.665 0.334 0.000
M12 Other specific arthropathies
0.665 0.334 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.665 0.334 0.000
M08 Juvenile arthritis
0.665 0.334 0.000
I50.9 Heart failure, unspecified
0.665 0.335 0.000
Q60-Q64 Congenital malformations of the urinary system
0.665 0.335 0.000
E11.8 With unspecified complications
0.665 0.335 0.000
E11.7 With multiple complications
0.665 0.335 0.000
E11.6 With other specified complications
0.665 0.335 0.000
E11.1 With ketoacidosis
0.665 0.335 0.000
E11.0 With coma
0.665 0.335 0.000
I35 Nonrheumatic aortic valve disorders
0.665 0.335 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.664 0.336 0.000
M34 Systemic sclerosis
0.664 0.336 0.000
M33 Dermatopolymyositis
0.664 0.336 0.000
M32 Systemic lupus erythematosus
0.664 0.336 0.000
M30 Polyarteritis nodosa and related conditions
0.664 0.336 0.000
I22.0 Subsequent myocardial infarction of anterior wall
0.664 0.336 0.000
M31.6 Other giant cell arteritis
0.664 0.336 0.000
D21 Other benign neoplasms of connective and other soft tissue
0.664 0.336 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.664 0.336 0.000
Y35-Y36 Legal intervention and operations of war
0.664 0.336 0.000
Y10-Y34 Event of undetermined intent
0.664 0.336 0.000
Y00-Y09 Assault
0.664 0.336 0.000
X85-X99 Assault
0.664 0.336 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.664 0.336 0.000
X50-X57 Overexertion, travel and privation
0.664 0.336 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.664 0.336 0.000
X30-X39 Exposure to forces of nature
0.664 0.336 0.000
X20-X29 Contact with venomous animals and plants
0.664 0.336 0.000
X10-X19 Contact with heat and hot substances
0.664 0.336 0.000
X00-X09 Exposure to smoke, fire and flames
0.664 0.336 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.664 0.336 0.000
W75-W84 Other accidental threats to breathing
0.664 0.336 0.000
W65-W74 Accidental drowning and submersion
0.664 0.336 0.000
W50-W64 Exposure to animate mechanical forces
0.664 0.336 0.000
V98-V99 Other and unspecified transport accidents
0.664 0.336 0.000
V95-V97 Air and space transport accidents
0.664 0.336 0.000
V90-V94 Water transport accidents
0.664 0.336 0.000
V80-V89 Other land transport accidents
0.664 0.336 0.000
V70-V79 Bus occupant injured in transport accident
0.664 0.336 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.664 0.336 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.664 0.336 0.000
V40-V49 Car occupant injured in transport accident
0.664 0.336 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.664 0.336 0.000
V01-V09 Pedestrian injured in transport accident
0.664 0.336 0.000
D75.9 Disease of blood and blood-forming organs, unspecified
0.663 0.337 0.000
M75 Shoulder lesions
0.662 0.338 0.000
A46 Erysipelas
0.661 0.339 0.000
D75.1 Secondary polycythaemia
0.661 0.339 0.000
H40 Glaucoma
0.660 0.340 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.660 0.340 0.000
Z75 Problems related to medical facilities and other health care
0.659 0.341 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.658 0.342 0.000
H25.1 Senile nuclear cataract
0.658 0.342 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.658 0.342 0.000
D06.9 Cervix, unspecified
0.658 0.342 0.000
E11.5 With peripheral circulatory complications
0.657 0.343 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.657 0.343 0.000
H31 Other disorders of choroid
0.657 0.343 0.000
H30 Chorioretinal inflammation
0.657 0.343 0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.657 0.343 0.000
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness
0.656 0.344 0.000
W22.9 Unspecified place
0.656 0.344 0.000
R46 Symptoms and signs involving appearance and behaviour
0.656 0.344 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.656 0.344 0.000
R43 Disturbances of smell and taste
0.656 0.344 0.000
M48.06 Spinal stenosis (Lumbar region)
0.655 0.345 0.000
E78.6 Lipoprotein deficiency
0.654 0.346 0.000
E78.4 Other hyperlipidaemia
0.654 0.346 0.000
E78.3 Hyperchylomicronaemia
0.654 0.346 0.000
E78.1 Pure hyperglyceridaemia
0.654 0.346 0.000
J38.2 Nodules of vocal cords
0.653 0.346 0.000
R41.2 Retrograde amnesia
0.653 0.347 0.000
M47.98 Spondylosis, unspecified (Sacral and sacrococcygeal region)
0.653 0.347 0.000
M47.95 Spondylosis, unspecified (Thoracolumbar region)
0.653 0.347 0.000
M47.94 Spondylosis, unspecified (Thoracic region)
0.653 0.347 0.000
M47.93 Spondylosis, unspecified (Cervicothoracic region)
0.653 0.347 0.000
M47.91 Spondylosis, unspecified (Occipito-atlanto-axial region)
0.653 0.347 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.651 0.349 0.000
I83 Varicose veins of lower extremities
0.651 0.349 0.000
S70 Superficial injury of hip and thigh
0.651 0.349 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.651 0.349 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.651 0.349 0.000
Z09.7 Follow-up examination after combined treatment for other conditions
0.651 0.349 0.000
Z09.4 Follow-up examination after treatment of fracture
0.651 0.349 0.000
Z09.3 Follow-up examination after psychotherapy
0.651 0.349 0.000
Z09.1 Follow-up examination after radiotherapy for other conditions
0.651 0.349 0.000
D26 Other benign neoplasms of uterus
0.651 0.349 0.000
I88 Nonspecific lymphadenitis
0.650 0.350 0.000
H27.8 Other specified disorders of lens
0.649 0.351 0.000
H53-H54 Visual disturbances and blindness
0.649 0.351 0.000
M06.0 Seronegative rheumatoid arthritis
0.649 0.351 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.649 0.351 0.000
S06 Intracranial injury
0.649 0.351 0.000
B35-B49 Mycoses
0.648 0.352 0.000
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters
0.647 0.353 0.000
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters
0.647 0.353 0.000
B96.0 Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified to other chapters
0.647 0.353 0.000
D14 Benign neoplasm of middle ear and respiratory system
0.647 0.353 0.000
N17-N19 Renal failure
0.647 0.353 0.000
V10-V19 Pedal cyclist injured in transport accident
0.646 0.354 0.000
S20-S29 Injuries to the thorax
0.646 0.354 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.646 0.354 0.000
D22 Melanocytic naevi
0.645 0.355 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.645 0.355 0.000
T84.1 Mechanical complication of internal fixation device of bones of limb
0.644 0.356 0.000
T18 Foreign body in alimentary tract
0.643 0.356 0.000
I45 Other conduction disorders
0.643 0.357 0.000
C50.8 Overlapping lesion of breast
0.643 0.357 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.643 0.357 0.000
H33.5 Other retinal detachments
0.642 0.358 0.000
R04.0 Epistaxis
0.642 0.358 0.000
E83.4 Disorders of magnesium metabolism
0.642 0.358 0.000
I51.6 Cardiovascular disease, unspecified
0.641 0.358 0.000
I51.5 Myocardial degeneration
0.641 0.358 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.641 0.358 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.641 0.358 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.641 0.358 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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