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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs117414661
log Bayes Factor = 14.5592
Chromosome 10   position 21,569,423  (GRCh37) Explore rs117414661 on Ensembl!
Variant rs117414661 is part of Cluster X0039

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XI Diseases of the digestive system
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
0.999 0.001 0.000
K40-K46 Hernia
0.999 0.001 0.000
I25 Chronic ischaemic heart disease
0.999 0.001 0.000
K20-K31 Diseases of oesophagus, stomach and duodenum
0.997 0.003 0.000
Chapter XIV Diseases of the genitourinary system
0.997 0.003 0.000
K40 Inguinal hernia
0.991 0.009 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.988 0.012 0.000
K29 Gastritis and duodenitis
0.987 0.013 0.000
K44 Diaphragmatic hernia
0.987 0.013 0.000
C15-C26 Malignant neoplasms of digestive organs
0.986 0.014 0.000
K29.7 Gastritis, unspecified
0.985 0.015 0.000
N17-N19 Renal failure
0.983 0.017 0.000
K44.9 Diaphragmatic hernia without obstruction or gangrene
0.978 0.022 0.000
K40.9 Unilateral or unspecified inguinal hernia, without obstruction or gangrene
0.977 0.023 0.000
C60-C63 Malignant neoplasms of male genital organs
0.973 0.027 0.000
I60-I69 Cerebrovascular diseases
0.971 0.029 0.000
I30-I52 Other forms of heart disease
0.970 0.030 0.000
N10-N16 Renal tubulo-interstitial diseases
0.967 0.033 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.962 0.038 0.000
C61 Malignant neoplasm of prostate
0.953 0.047 0.000
K31 Other diseases of stomach and duodenum
0.951 0.049 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.947 0.053 0.000
I10-I15 Hypertensive diseases
0.943 0.057 0.000
C51-C58 Malignant neoplasms of female genital organs
0.940 0.060 0.000
N17 Acute renal failure
0.934 0.066 0.000
I25.2 Old myocardial infarction
0.933 0.067 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.923 0.077 0.000
D10-D36 Benign neoplasms
0.923 0.077 0.000
K22 Other diseases of oesophagus
0.916 0.084 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.915 0.085 0.000
N19 Unspecified renal failure
0.914 0.086 0.000
C50-C50 Malignant neoplasm of breast
0.912 0.088 0.000
N13 Obstructive and reflux uropathy
0.910 0.090 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.907 0.093 0.000
K25 Gastric ulcer
0.907 0.093 0.000
N17.9 Acute renal failure, unspecified
0.900 0.100 0.000
C20 Malignant neoplasm of rectum
0.898 0.102 0.000
I63 Cerebral infarction
0.897 0.103 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.889 0.111 0.000
K31.8 Other specified diseases of stomach and duodenum
0.887 0.113 0.000
I10 Essential (primary) hypertension
0.886 0.114 0.000
K83 Other diseases of biliary tract
0.883 0.117 0.000
N60-N64 Disorders of breast
0.881 0.119 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.879 0.121 0.000
I67 Other cerebrovascular diseases
0.875 0.125 0.000
E10-E14 Diabetes mellitus
0.871 0.129 0.000
I25.1 Atherosclerotic heart disease
0.869 0.131 0.000
I20 Angina pectoris
0.865 0.135 0.000
I31 Other diseases of pericardium
0.862 0.138 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.859 0.141 0.000
Chapter VII Diseases of the eye and adnexa
0.858 0.142 0.000
D17 Benign lipomatous neoplasm
0.857 0.143 0.000
I71 Aortic aneurysm and dissection
0.854 0.146 0.000
C54 Malignant neoplasm of corpus uteri
0.851 0.149 0.000
N13.3 Other and unspecified hydronephrosis
0.850 0.150 0.000
C18 Malignant neoplasm of colon
0.850 0.150 0.000
I34 Nonrheumatic mitral valve disorders
0.849 0.151 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.849 0.151 0.000
C50 Malignant neoplasm of breast
0.849 0.151 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.839 0.161 0.000
K70-K77 Diseases of liver
0.839 0.161 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.838 0.162 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.838 0.162 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.834 0.166 0.000
E10 Insulin-dependent diabetes mellitus
0.834 0.166 0.000
N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.828 0.172 0.000
Chapter I Certain infectious and parasitic diseases
0.828 0.172 0.000
Chapter XXII Codes for special purposes
0.827 0.173 0.000
I42 Cardiomyopathy
0.824 0.176 0.000
K86 Other diseases of pancreas
0.821 0.179 0.000
K40.3 Unilateral or unspecified inguinal hernia, with obstruction, without gangrene
0.820 0.180 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.818 0.182 0.000
I24 Other acute ischaemic heart diseases
0.818 0.182 0.000
D22 Melanocytic naevi
0.817 0.183 0.000
N94 Pain and other conditions associated with female genital organs and menstrual cycle
0.815 0.185 0.000
H30-H36 Disorders of choroid and retina
0.814 0.186 0.000
N99-N99 Other disorders of the genitourinary system
0.813 0.187 0.000
I73 Other peripheral vascular diseases
0.808 0.192 0.000
N60 Benign mammary dysplasia
0.805 0.195 0.000
N90 Other noninflammatory disorders of vulva and perineum
0.804 0.196 0.000
K40.2 Bilateral inguinal hernia, without obstruction or gangrene
0.803 0.197 0.000
E10.9 Without complications
0.802 0.198 0.000
D17.2 Benign lipomatous neoplasm of skin and subcutaneous tissue of limbs
0.801 0.199 0.000
I63.8 Other cerebral infarction
0.797 0.203 0.000
K35-K38 Diseases of appendix
0.795 0.205 0.000
I44 Atrioventricular and left bundle-branch block
0.789 0.211 0.000
I11 Hypertensive heart disease
0.788 0.212 0.000
N00-N08 Glomerular diseases
0.787 0.213 0.000
C54.1 Endometrium
0.787 0.213 0.000
I69 Sequelae of cerebrovascular disease
0.787 0.213 0.000
C50.4 Upper-outer quadrant of breast
0.785 0.215 0.000
K83.0 Cholangitis
0.784 0.216 0.000
D35 Benign neoplasm of other and unspecified endocrine glands
0.783 0.217 0.000
L60-L75 Disorders of skin appendages
0.782 0.218 0.000
K83.8 Other specified diseases of biliary tract
0.779 0.221 0.000
K29.1 Other acute gastritis
0.779 0.221 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.777 0.223 0.000
I74 Arterial embolism and thrombosis
0.776 0.224 0.000
N85 Other noninflammatory disorders of uterus, except cervix
0.776 0.224 0.000
L08 Other local infections of skin and subcutaneous tissue
0.773 0.227 0.000
K22.1 Ulcer of oesophagus
0.772 0.228 0.000
I20.0 Unstable angina
0.771 0.229 0.000
K31.5 Obstruction of duodenum
0.770 0.230 0.000
K27 Peptic ulcer, site unspecified
0.770 0.230 0.000
N94.1 Dyspareunia
0.766 0.234 0.000
K50-K52 Noninfective enteritis and colitis
0.766 0.234 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.764 0.236 0.000
C64-C68 Malignant neoplasms of urinary tract
0.759 0.241 0.000
N10 Acute tubulo-interstitial nephritis
0.758 0.242 0.000
E20-E35 Disorders of other endocrine glands
0.758 0.242 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.758 0.242 0.000
K29.6 Other gastritis
0.756 0.244 0.000
N83.2 Other and unspecified ovarian cysts
0.754 0.246 0.000
H36 Retinal disorders in diseases classified elsewhere
0.754 0.246 0.000
I67.1 Cerebral aneurysm, nonruptured
0.753 0.247 0.000
C55 Malignant neoplasm of uterus, part unspecified
0.752 0.248 0.000
I31.3 Pericardial effusion (noninflammatory)
0.751 0.249 0.000
K25.7 Chronic without haemorrhage or perforation
0.750 0.250 0.000
K41 Femoral hernia
0.750 0.250 0.000
N86 Erosion and ectropion of cervix uteri
0.749 0.251 0.000
M05-M14 Inflammatory polyarthropathies
0.749 0.251 0.000
C16 Malignant neoplasm of stomach
0.748 0.252 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.748 0.252 0.000
K25.4 Chronic or unspecified with haemorrhage
0.747 0.253 0.000
L20-L30 Dermatitis and eczema
0.747 0.253 0.000
I45 Other conduction disorders
0.746 0.254 0.000
I63.9 Cerebral infarction, unspecified
0.745 0.255 0.000
D18 Haemangioma and lymphangioma, any site
0.744 0.256 0.000
K31.9 Disease of stomach and duodenum, unspecified
0.743 0.257 0.000
I77 Other disorders of arteries and arterioles
0.742 0.258 0.000
N18 Chronic renal failure
0.742 0.258 0.000
I22 Subsequent myocardial infarction
0.739 0.261 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.738 0.262 0.000
C56 Malignant neoplasm of ovary
0.738 0.262 0.000
I47 Paroxysmal tachycardia
0.737 0.263 0.000
C22.9 Liver, unspecified
0.733 0.267 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.733 0.267 0.000
K22.0 Achalasia of cardia
0.732 0.268 0.000
N64 Other disorders of breast
0.730 0.270 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.729 0.270 0.000
I67.9 Cerebrovascular disease, unspecified
0.729 0.271 0.000
K22.7 Barrett's oesophagus
0.728 0.272 0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified
0.727 0.273 0.000
L08.9 Local infection of skin and subcutaneous tissue, unspecified
0.726 0.274 0.000
I49 Other cardiac arrhythmias
0.726 0.274 0.000
K46 Unspecified abdominal hernia
0.726 0.274 0.000
L40-L45 Papulosquamous disorders
0.726 0.274 0.000
K22.9 Disease of oesophagus, unspecified
0.724 0.276 0.000
N13.5 Kinking and stricture of ureter without hydronephrosis
0.724 0.276 0.000
K70 Alcoholic liver disease
0.723 0.277 0.000
M50-M54 Other dorsopathies
0.722 0.278 0.000
I78 Diseases of capillaries
0.722 0.278 0.000
D24 Benign neoplasm of breast
0.719 0.281 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.719 0.281 0.000
K86.1 Other chronic pancreatitis
0.719 0.281 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.719 0.281 0.000
D00-D09 In situ neoplasms
0.719 0.281 0.000
H33 Retinal detachments and breaks
0.719 0.281 0.000
Chapter XX External causes of morbidity and mortality
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.717 0.283 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.717 0.283 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.717 0.283 0.000
I23 Certain current complications following acute myocardial infarction
0.717 0.283 0.000
K45 Other abdominal hernia
0.716 0.283 0.000
I25.6 Silent myocardial ischaemia
0.716 0.284 0.000
I25.5 Ischaemic cardiomyopathy
0.716 0.284 0.000
I25.4 Coronary artery aneurysm
0.716 0.284 0.000
I25.3 Aneurysm of heart
0.716 0.284 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.716 0.284 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.716 0.284 0.000
K28 Gastrojejunal ulcer
0.715 0.285 0.000
K23 Disorders of oesophagus in diseases classified elsewhere
0.715 0.285 0.000
I05-I09 Chronic rheumatic heart diseases
0.715 0.285 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.715 0.285 0.000
I33 Acute and subacute endocarditis
0.715 0.285 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.714 0.286 0.000
D21 Other benign neoplasms of connective and other soft tissue
0.711 0.289 0.000
H36.0 Diabetic retinopathy
0.711 0.289 0.000
I62 Other nontraumatic intracranial haemorrhage
0.711 0.289 0.000
K40.4 Unilateral or unspecified inguinal hernia, with gangrene
0.710 0.289 0.000
K40.1 Bilateral inguinal hernia, with gangrene
0.710 0.289 0.000
K40.0 Bilateral inguinal hernia, with obstruction, without gangrene
0.710 0.289 0.000
K43 Ventral hernia
0.709 0.291 0.000
D36 Benign neoplasm of other and unspecified sites
0.709 0.291 0.000
C50.5 Lower-outer quadrant of breast
0.709 0.291 0.000
K29.9 Gastroduodenitis, unspecified
0.708 0.292 0.000
K29.4 Chronic atrophic gastritis
0.708 0.292 0.000
K29.3 Chronic superficial gastritis
0.708 0.292 0.000
K29.2 Alcoholic gastritis
0.708 0.292 0.000
K44.1 Diaphragmatic hernia with gangrene
0.707 0.292 0.000
K44.0 Diaphragmatic hernia with obstruction, without gangrene
0.707 0.292 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.707 0.293 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.707 0.293 0.000
C21 Malignant neoplasm of anus and anal canal
0.707 0.293 0.000
C17 Malignant neoplasm of small intestine
0.707 0.293 0.000
C23 Malignant neoplasm of gallbladder
0.707 0.293 0.000
I34.0 Mitral (valve) insufficiency
0.706 0.294 0.000
I70 Atherosclerosis
0.706 0.294 0.000
K83.1 Obstruction of bile duct
0.706 0.294 0.000
K22.6 Gastro-oesophageal laceration-haemorrhage syndrome
0.705 0.295 0.000
C53 Malignant neoplasm of cervix uteri
0.705 0.295 0.000
I34.1 Mitral (valve) prolapse
0.704 0.296 0.000
I46 Cardiac arrest
0.703 0.297 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.703 0.297 0.000
K25.9 Unspecified as acute or chronic, without haemorrhage or perforation
0.701 0.299 0.000
M06 Other rheumatoid arthritis
0.701 0.299 0.000
E40-E46 Malnutrition
0.700 0.299 0.000
A30-A49 Other bacterial diseases
0.700 0.300 0.000
N60.3 Fibrosclerosis of breast
0.700 0.300 0.000
C63 Malignant neoplasm of other and unspecified male genital organs
0.697 0.302 0.000
C62 Malignant neoplasm of testis
0.697 0.302 0.000
C60 Malignant neoplasm of penis
0.697 0.302 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.696 0.303 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.696 0.303 0.000
C25 Malignant neoplasm of pancreas
0.696 0.304 0.000
D17.6 Benign lipomatous neoplasm of spermatic cord
0.696 0.304 0.000
I52 Other heart disorders in diseases classified elsewhere
0.695 0.305 0.000
I48 Atrial fibrillation and flutter
0.695 0.305 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.695 0.305 0.000
I41 Myocarditis in diseases classified elsewhere
0.695 0.305 0.000
I40 Acute myocarditis
0.695 0.305 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.695 0.305 0.000
I37 Pulmonary valve disorders
0.695 0.305 0.000
I36 Nonrheumatic tricuspid valve disorders
0.695 0.305 0.000
I32 Pericarditis in diseases classified elsewhere
0.695 0.305 0.000
I30 Acute pericarditis
0.695 0.305 0.000
I38 Endocarditis, valve unspecified
0.695 0.305 0.000
M20-M25 Other joint disorders
0.694 0.306 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.693 0.306 0.000
N15 Other renal tubulo-interstitial diseases
0.693 0.306 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.693 0.306 0.000
N11 Chronic tubulo-interstitial nephritis
0.693 0.306 0.000
D17.9 Benign lipomatous neoplasm, unspecified
0.693 0.307 0.000
I31.9 Disease of pericardium, unspecified
0.692 0.308 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.692 0.308 0.000
K65-K67 Diseases of peritoneum
0.691 0.309 0.000
K25.3 Acute without haemorrhage or perforation
0.691 0.309 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.691 0.309 0.000
C15 Malignant neoplasm of oesophagus
0.690 0.310 0.000
K22.4 Dyskinesia of oesophagus
0.690 0.310 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.689 0.310 0.000
I72 Other aneurysm
0.689 0.310 0.000
D32 Benign neoplasm of meninges
0.689 0.311 0.000
Chapter VIII Diseases of the ear and mastoid process
0.688 0.311 0.000
N97 Female infertility
0.688 0.312 0.000
S80-S89 Injuries to the knee and lower leg
0.688 0.312 0.000
C18.9 Colon, unspecified
0.687 0.313 0.000
N90.4 Leukoplakia of vulva
0.685 0.315 0.000
N92 Excessive, frequent and irregular menstruation
0.684 0.316 0.000
N85.0 Endometrial glandular hyperplasia
0.684 0.316 0.000
C18.4 Transverse colon
0.682 0.318 0.000
K31.6 Fistula of stomach and duodenum
0.682 0.318 0.000
K31.4 Gastric diverticulum
0.682 0.318 0.000
K31.3 Pylorospasm, not elsewhere classified
0.682 0.318 0.000
K31.2 Hourglass stricture and stenosis of stomach
0.682 0.318 0.000
K31.1 Adult hypertrophic pyloric stenosis
0.682 0.318 0.000
K31.0 Acute dilatation of stomach
0.682 0.318 0.000
I42.0 Dilated cardiomyopathy
0.681 0.319 0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified
0.681 0.319 0.000
I44.7 Left bundle-branch block, unspecified
0.680 0.320 0.000
L50-L54 Urticaria and erythema
0.679 0.321 0.000
L10-L14 Bullous disorders
0.679 0.321 0.000
I11.9 Hypertensive heart disease without (congestive) heart failure
0.677 0.323 0.000
K31.7 Polyp of stomach and duodenum
0.677 0.323 0.000
I15 Secondary hypertension
0.676 0.324 0.000
I13 Hypertensive heart and renal disease
0.676 0.324 0.000
N60.1 Diffuse cystic mastopathy
0.675 0.325 0.000
I61 Intracerebral haemorrhage
0.675 0.325 0.000
C57 Malignant neoplasm of other and unspecified female genital organs
0.674 0.326 0.000
C51 Malignant neoplasm of vulva
0.674 0.326 0.000
C58 Malignant neoplasm of placenta
0.674 0.326 0.000
C52 Malignant neoplasm of vagina
0.674 0.326 0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.671 0.329 0.000
B35-B49 Mycoses
0.670 0.330 0.000
N17.8 Other acute renal failure
0.670 0.330 0.000
N17.2 Acute renal failure with medullary necrosis
0.670 0.330 0.000
N17.1 Acute renal failure with acute cortical necrosis
0.670 0.330 0.000
N17.0 Acute renal failure with tubular necrosis
0.670 0.330 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.668 0.332 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.668 0.332 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.667 0.333 0.000
D45 Polycythaemia vera
0.667 0.333 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.666 0.333 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.666 0.334 0.000
C18.6 Descending colon
0.665 0.335 0.000
H55-H59 Other disorders of eye and adnexa
0.664 0.336 0.000
L05 Pilonidal cyst
0.664 0.336 0.000
Chapter V Mental and behavioural disorders
0.663 0.337 0.000
D35.1 Parathyroid gland
0.662 0.338 0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.662 0.338 0.000
D33 Benign neoplasm of brain and other parts of central nervous system
0.662 0.338 0.000
D31 Benign neoplasm of eye and adnexa
0.662 0.338 0.000
D30 Benign neoplasm of urinary organs
0.662 0.338 0.000
D29 Benign neoplasm of male genital organs
0.662 0.338 0.000
D28 Benign neoplasm of other and unspecified female genital organs
0.662 0.338 0.000
D26 Other benign neoplasms of uterus
0.662 0.338 0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum
0.662 0.338 0.000
D19 Benign neoplasm of mesothelial tissue
0.662 0.338 0.000
D16 Benign neoplasm of bone and articular cartilage
0.662 0.338 0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs
0.662 0.338 0.000
D14 Benign neoplasm of middle ear and respiratory system
0.662 0.338 0.000
D10 Benign neoplasm of mouth and pharynx
0.662 0.338 0.000
D34 Benign neoplasm of thyroid gland
0.662 0.338 0.000
N87 Dysplasia of cervix uteri
0.661 0.339 0.000
N90.9 Noninflammatory disorder of vulva and perineum, unspecified
0.660 0.340 0.000
D22.4 Melanocytic naevi of scalp and neck
0.660 0.340 0.000
I51 Complications and ill-defined descriptions of heart disease
0.660 0.340 0.000
D22.7 Melanocytic naevi of lower limb, including hip
0.658 0.342 0.000
E11 Non-insulin-dependent diabetes mellitus
0.658 0.342 0.000
K22.5 Diverticulum of oesophagus, acquired
0.656 0.343 0.000
K22.3 Perforation of oesophagus
0.656 0.343 0.000
I24.8 Other forms of acute ischaemic heart disease
0.656 0.344 0.000
N03 Chronic nephritic syndrome
0.656 0.344 0.000
C50.3 Lower-inner quadrant of breast
0.655 0.345 0.000
C79 Secondary malignant neoplasm of other sites
0.655 0.345 0.000
N83.8 Other noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.654 0.346 0.000
N89 Other noninflammatory disorders of vagina
0.653 0.347 0.000
I42.9 Cardiomyopathy, unspecified
0.653 0.347 0.000
N13.9 Obstructive and reflux uropathy, unspecified
0.652 0.348 0.000
N13.8 Other obstructive and reflux uropathy
0.652 0.348 0.000
N13.7 Vesicoureteral-reflux-associated uropathy
0.652 0.348 0.000
N13.6 Pyonephrosis
0.652 0.348 0.000
N13.4 Hydroureter
0.652 0.348 0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction
0.652 0.348 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.651 0.349 0.000
N98 Complications associated with artificial fertilisation
0.650 0.349 0.000
N91 Absent, scanty and rare menstruation
0.650 0.349 0.000
N82 Fistulae involving female genital tract
0.650 0.349 0.000
N96 Habitual aborter
0.650 0.349 0.000
M06.9 Rheumatoid arthritis, unspecified
0.650 0.350 0.000
K25.6 Chronic or unspecified with both haemorrhage and perforation
0.650 0.350 0.000
K25.5 Chronic or unspecified with perforation
0.650 0.350 0.000
K25.2 Acute with both haemorrhage and perforation
0.650 0.350 0.000
K25.1 Acute with perforation
0.650 0.350 0.000
K25.0 Acute with haemorrhage
0.650 0.350 0.000
M70-M79 Other soft tissue disorders
0.650 0.350 0.000
I73.9 Peripheral vascular disease, unspecified
0.650 0.350 0.000
I73.0 Raynaud's syndrome
0.649 0.351 0.000
K22.2 Oesophageal obstruction
0.648 0.352 0.000
I44.0 Atrioventricular block, first degree
0.647 0.353 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.647 0.353 0.000
N90.5 Atrophy of vulva
0.646 0.354 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.643 0.356 0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.643 0.357 0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.643 0.357 0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.643 0.357 0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.643 0.357 0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.643 0.357 0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.643 0.357 0.000
M50 Cervical disk disorders
0.641 0.359 0.000
M65-M68 Disorders of synovium and tendon
0.640 0.359 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.640 0.360 0.000
I67.8 Other specified cerebrovascular diseases
0.639 0.360 0.000
N88 Other noninflammatory disorders of cervix uteri
0.639 0.361 0.000
K75 Other inflammatory liver diseases
0.639 0.361 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.639 0.361 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.638 0.362 0.000
K35 Acute appendicitis
0.637 0.363 0.000
M86-M90 Other osteopathies
0.637 0.363 0.000
C50.9 Breast, unspecified
0.637 0.363 0.000
K85 Acute pancreatitis
0.636 0.364 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.636 0.364 0.000
K50 Crohn's disease [regional enteritis]
0.635 0.364 0.000
E70-E90 Metabolic disorders
0.635 0.364 0.000
D22.6 Melanocytic naevi of upper limb, including shoulder
0.635 0.365 0.000
K29.0 Acute haemorrhagic gastritis
0.634 0.365 0.000
H52 Disorders of refraction and accommodation
0.634 0.366 0.000
I69.3 Sequelae of cerebral infarction
0.634 0.366 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.633 0.367 0.000
E23 Hypofunction and other disorders of pituitary gland
0.633 0.367 0.000
K83.9 Disease of biliary tract, unspecified
0.633 0.367 0.000
K83.5 Biliary cyst
0.633 0.367 0.000
K83.4 Spasm of sphincter of Oddi
0.633 0.367 0.000
K83.3 Fistula of bile duct
0.633 0.367 0.000
K83.2 Perforation of bile duct
0.633 0.367 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.633 0.367 0.000
D11 Benign neoplasm of major salivary glands
0.632 0.367 0.000
E50-E64 Other nutritional deficiencies
0.632 0.368 0.000
N61 Inflammatory disorders of breast
0.631 0.369 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.630 0.370 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.630 0.370 0.000
D46 Myelodysplastic syndromes
0.630 0.370 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.630 0.370 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.630 0.370 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.630 0.370 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.630 0.370 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.630 0.370 0.000
I20.8 Other forms of angina pectoris
0.629 0.370 0.000
E14 Unspecified diabetes mellitus
0.629 0.371 0.000
D22.0 Melanocytic naevi of lip
0.628 0.372 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.628 0.372 0.000
I67.7 Cerebral arteritis, not elsewhere classified
0.628 0.372 0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.628 0.372 0.000
I67.5 Moyamoya disease
0.628 0.372 0.000
I67.4 Hypertensive encephalopathy
0.628 0.372 0.000
I67.3 Progressive vascular leukoencephalopathy
0.628 0.372 0.000
I67.2 Cerebral atherosclerosis
0.628 0.372 0.000
I67.0 Dissection of cerebral arteries, nonruptured
0.628 0.372 0.000
Chapter VI Diseases of the nervous system
0.628 0.372 0.000
K86.3 Pseudocyst of pancreas
0.627 0.373 0.000
E10.1 With ketoacidosis
0.626 0.374 0.000
M40-M43 Deforming dorsopathies
0.625 0.374 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.625 0.375 0.000
E13 Other specified diabetes mellitus
0.624 0.375 0.000
E12 Malnutrition-related diabetes mellitus
0.624 0.375 0.000
D13 Benign neoplasm of other and ill-defined parts of digestive system
0.622 0.378 0.000
L60 Nail disorders
0.622 0.378 0.000
S20-S29 Injuries to the thorax
0.622 0.378 0.000
L29 Pruritus
0.621 0.379 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.621 0.379 0.000
I20.1 Angina pectoris with documented spasm
0.620 0.380 0.000
N92.0 Excessive and frequent menstruation with regular cycle
0.619 0.381 0.000
I47.1 Supraventricular tachycardia
0.619 0.381 0.000
I12 Hypertensive renal disease
0.618 0.381 0.000
I31.8 Other specified diseases of pericardium
0.618 0.382 0.000
I31.2 Haemopericardium, not elsewhere classified
0.618 0.382 0.000
I31.1 Chronic constrictive pericarditis
0.618 0.382 0.000
I31.0 Chronic adhesive pericarditis
0.618 0.382 0.000
L72 Follicular cysts of skin and subcutaneous tissue
0.617 0.383 0.000
R47-R49 Symptoms and signs involving speech and voice
0.617 0.383 0.000
C18.7 Sigmoid colon
0.617 0.383 0.000
K51 Ulcerative colitis
0.617 0.383 0.000
M91-M94 Chondropathies
0.616 0.384 0.000
M60-M63 Disorders of muscles
0.616 0.384 0.000
M00-M03 Infectious arthropathies
0.616 0.384 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.616 0.384 0.000
D18.0 Haemangioma, any site
0.616 0.384 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.615 0.385 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.615 0.385 0.000
H10-H13 Disorders of conjunctiva
0.615 0.385 0.000
N18.9 Chronic renal failure, unspecified
0.614 0.385 0.000
D17.5 Benign lipomatous neoplasm of intra-abdominal organs
0.614 0.386 0.000
D17.4 Benign lipomatous neoplasm of intrathoracic organs
0.614 0.386 0.000
K74 Fibrosis and cirrhosis of liver
0.614 0.386 0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.614 0.386 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.614 0.386 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.614 0.386 0.000
D17.7 Benign lipomatous neoplasm of other sites
0.613 0.386 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.613 0.387 0.000
I71.8 Aortic aneurysm of unspecified site, ruptured
0.612 0.387 0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.612 0.387 0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.612 0.387 0.000
I71.3 Abdominal aortic aneurysm, ruptured
0.612 0.387 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.612 0.387 0.000
I71.1 Thoracic aortic aneurysm, ruptured
0.612 0.387 0.000
I71.0 Dissection of aorta [any part]
0.612 0.387 0.000
N60.2 Fibroadenosis of breast
0.612 0.388 0.000
E10.3 With ophthalmic complications
0.612 0.388 0.000
L89 Decubitus ulcer
0.612 0.388 0.000
I60 Subarachnoid haemorrhage
0.611 0.389 0.000
C54.9 Corpus uteri, unspecified
0.610 0.390 0.000
C54.8 Overlapping lesion of corpus uteri
0.610 0.390 0.000
C54.3 Fundus uteri
0.610 0.390 0.000
C54.2 Myometrium
0.610 0.390 0.000
C54.0 Isthmus uteri
0.610 0.390 0.000
C18.8 Overlapping lesion of colon
0.609 0.391 0.000
C18.5 Splenic flexure
0.609 0.391 0.000
C18.3 Hepatic flexure
0.609 0.391 0.000
C18.1 Appendix
0.609 0.391 0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.609 0.391 0.000
I34.8 Other nonrheumatic mitral valve disorders
0.609 0.391 0.000
I34.2 Nonrheumatic mitral (valve) stenosis
0.609 0.391 0.000
C50.6 Axillary tail of breast
0.609 0.391 0.000
C50.0 Nipple and areola
0.609 0.391 0.000
K86.8 Other specified diseases of pancreas
0.608 0.392 0.000
I49.4 Other and unspecified premature depolarisation
0.608 0.392 0.000
C18.2 Ascending colon
0.607 0.392 0.000
D22.3 Melanocytic naevi of other and unspecified parts of face
0.607 0.393 0.000
K27.9 Unspecified as acute or chronic, without haemorrhage or perforation
0.606 0.394 0.000
L84 Corns and callosities
0.606 0.394 0.000
I20.9 Angina pectoris, unspecified
0.606 0.394 0.000
K86.2 Cyst of pancreas
0.605 0.395 0.000
D37.1 Stomach
0.604 0.395 0.000
S90-S99 Injuries to the ankle and foot
0.604 0.396 0.000
I22.0 Subsequent myocardial infarction of anterior wall
0.604 0.396 0.000
E83 Disorders of mineral metabolism
0.603 0.397 0.000
L04 Acute lymphadenitis
0.602 0.398 0.000
L01 Impetigo
0.602 0.398 0.000
L00 Staphylococcal scalded skin syndrome
0.602 0.398 0.000
K77 Liver disorders in diseases classified elsewhere
0.601 0.399 0.000
K73 Chronic hepatitis, not elsewhere classified
0.601 0.399 0.000
K72 Hepatic failure, not elsewhere classified
0.601 0.399 0.000
K71 Toxic liver disease
0.601 0.399 0.000
C22.7 Other specified carcinomas of liver
0.601 0.399 0.000
C22.4 Other sarcomas of liver
0.601 0.399 0.000
C22.3 Angiosarcoma of liver
0.601 0.399 0.000
C22.2 Hepatoblastoma
0.601 0.399 0.000
C22.1 Intrahepatic bile duct carcinoma
0.601 0.399 0.000
C22.0 Liver cell carcinoma
0.601 0.399 0.000
T66-T78 Other and unspecified effects of external causes
0.601 0.399 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.601 0.399 0.000
B15-B19 Viral hepatitis
0.599 0.401 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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