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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs117439611
log Bayes Factor = 14.8831
Chromosome 12   position 520,944  (GRCh37) Explore rs117439611 on Ensembl!
Variant rs117439611 is part of Cluster X0277

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.999 0.001 0.000
I25 Chronic ischaemic heart disease
0.999 0.001 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.998 0.002 0.000
Chapter XX External causes of morbidity and mortality
0.998 0.002 0.000
I30-I52 Other forms of heart disease
0.997 0.003 0.000
R00 Abnormalities of heart beat
0.997 0.003 0.000
Chapter XI Diseases of the digestive system
0.995 0.005 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.994 0.006 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.994 0.006 0.000
R00.1 Bradycardia, unspecified
0.991 0.009 0.000
I60-I69 Cerebrovascular diseases
0.990 0.010 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.990 0.010 0.000
I25.1 Atherosclerotic heart disease
0.986 0.014 0.000
Chapter X Diseases of the respiratory system
0.985 0.015 0.000
J30-J39 Other diseases of upper respiratory tract
0.984 0.016 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.984 0.016 0.000
J34 Other disorders of nose and nasal sinuses
0.979 0.021 0.000
I21 Acute myocardial infarction
0.976 0.024 0.000
K81 Cholecystitis
0.972 0.028 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.972 0.028 0.000
S00-S09 Injuries to the head
0.966 0.034 0.000
R06 Abnormalities of breathing
0.948 0.052 0.000
Chapter VIII Diseases of the ear and mastoid process
0.944 0.056 0.000
K80 Cholelithiasis
0.944 0.056 0.000
I63 Cerebral infarction
0.944 0.056 0.000
I21.9 Acute myocardial infarction, unspecified
0.942 0.058 0.000
I49 Other cardiac arrhythmias
0.941 0.059 0.000
I44 Atrioventricular and left bundle-branch block
0.939 0.061 0.000
K70-K77 Diseases of liver
0.934 0.066 0.000
K81.1 Chronic cholecystitis
0.928 0.072 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.928 0.072 0.000
Chapter VI Diseases of the nervous system
0.924 0.076 0.000
Y83.6 Removal of other organ (partial) (total)
0.924 0.076 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.922 0.078 0.000
I67 Other cerebrovascular diseases
0.920 0.080 0.000
J34.8 Other specified disorders of nose and nasal sinuses
0.919 0.081 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.911 0.089 0.000
J34.2 Deviated nasal septum
0.910 0.090 0.000
J34.3 Hypertrophy of nasal turbinates
0.909 0.091 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.909 0.091 0.000
R00.0 Tachycardia, unspecified
0.906 0.094 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.901 0.099 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.893 0.107 0.000
R06.8 Other and unspecified abnormalities of breathing
0.890 0.110 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.885 0.115 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.880 0.120 0.000
I44.0 Atrioventricular block, first degree
0.879 0.121 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.873 0.127 0.000
I24 Other acute ischaemic heart diseases
0.873 0.127 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.871 0.129 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.870 0.130 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.870 0.130 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.865 0.135 0.000
K80.2 Calculus of gallbladder without cholecystitis
0.864 0.136 0.000
I63.9 Cerebral infarction, unspecified
0.864 0.136 0.000
J95-J99 Other diseases of the respiratory system
0.860 0.140 0.000
S01 Open wound of head
0.858 0.142 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.856 0.144 0.000
I35 Nonrheumatic aortic valve disorders
0.854 0.146 0.000
R00.2 Palpitations
0.852 0.148 0.000
K80.5 Calculus of bile duct without cholangitis or cholecystitis
0.852 0.148 0.000
I50 Heart failure
0.851 0.149 0.000
R10 Abdominal and pelvic pain
0.849 0.151 0.000
I22 Subsequent myocardial infarction
0.846 0.154 0.000
H65-H75 Diseases of middle ear and mastoid
0.845 0.155 0.000
K82 Other diseases of gallbladder
0.840 0.160 0.000
I47 Paroxysmal tachycardia
0.839 0.161 0.000
Y86 Sequelae of other accidents
0.839 0.161 0.000
R10.3 Pain localised to other parts of lower abdomen
0.838 0.162 0.000
W00-W19 Falls
0.835 0.165 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.833 0.167 0.000
G90-G99 Other disorders of the nervous system
0.833 0.167 0.000
I05-I09 Chronic rheumatic heart diseases
0.828 0.171 0.000
I51 Complications and ill-defined descriptions of heart disease
0.827 0.173 0.000
Y83.2 Surgical operation with anastomosis, bypass or graft
0.826 0.174 0.000
I49.5 Sick sinus syndrome
0.825 0.175 0.000
S06 Intracranial injury
0.824 0.176 0.000
K81.0 Acute cholecystitis
0.823 0.177 0.000
Y83.1 Surgical operation with implant of artificial internal device
0.819 0.181 0.000
S00 Superficial injury of head
0.816 0.184 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.814 0.186 0.000
J32 Chronic sinusitis
0.813 0.187 0.000
K74 Fibrosis and cirrhosis of liver
0.812 0.188 0.000
T92 Sequelae of injuries of upper limb
0.811 0.189 0.000
K86 Other diseases of pancreas
0.807 0.193 0.000
Chapter II Neoplasms
0.806 0.194 0.000
I67.8 Other specified cerebrovascular diseases
0.802 0.198 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.799 0.200 0.000
M50-M54 Other dorsopathies
0.798 0.202 0.000
I49.3 Ventricular premature depolarisation
0.797 0.203 0.000
I44.2 Atrioventricular block, complete
0.795 0.205 0.000
J31.0 Chronic rhinitis
0.793 0.207 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.793 0.207 0.000
K72 Hepatic failure, not elsewhere classified
0.792 0.208 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.791 0.209 0.000
I42 Cardiomyopathy
0.789 0.211 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.788 0.212 0.000
K81.9 Cholecystitis, unspecified
0.786 0.214 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.784 0.216 0.000
O36 Maternal care for other known or suspected foetal problems
0.783 0.217 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.783 0.217 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.783 0.217 0.000
T90 Sequelae of injuries of head
0.783 0.217 0.000
H90-H95 Other disorders of ear
0.781 0.219 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.781 0.219 0.000
Y83.8 Other surgical procedures
0.781 0.219 0.000
E70-E90 Metabolic disorders
0.779 0.221 0.000
R47-R49 Symptoms and signs involving speech and voice
0.778 0.222 0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.774 0.226 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.774 0.226 0.000
I71 Aortic aneurysm and dissection
0.772 0.228 0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.771 0.229 0.000
J98 Other respiratory disorders
0.770 0.230 0.000
X60-X84 Intentional self-harm
0.769 0.231 0.000
R06.5 Mouth breathing
0.767 0.233 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.765 0.235 0.000
S09 Other and unspecified injuries of head
0.764 0.236 0.000
J33 Nasal polyp
0.764 0.236 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.763 0.237 0.000
I62 Other nontraumatic intracranial haemorrhage
0.762 0.238 0.000
I67.2 Cerebral atherosclerosis
0.762 0.238 0.000
I20 Angina pectoris
0.762 0.238 0.000
H80-H83 Diseases of inner ear
0.762 0.238 0.000
I30 Acute pericarditis
0.761 0.238 0.000
E10-E14 Diabetes mellitus
0.761 0.239 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.760 0.240 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.760 0.240 0.000
R15 Faecal incontinence
0.760 0.240 0.000
I67.9 Cerebrovascular disease, unspecified
0.760 0.240 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.760 0.240 0.000
R04 Haemorrhage from respiratory passages
0.759 0.241 0.000
S40-S49 Injuries to the shoulder and upper arm
0.758 0.242 0.000
K76 Other diseases of liver
0.757 0.243 0.000
M80-M85 Disorders of bone density and structure
0.756 0.244 0.000
K83 Other diseases of biliary tract
0.755 0.245 0.000
R12 Heartburn
0.754 0.246 0.000
R42 Dizziness and giddiness
0.754 0.246 0.000
M05-M14 Inflammatory polyarthropathies
0.753 0.247 0.000
C15-C26 Malignant neoplasms of digestive organs
0.752 0.248 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.751 0.249 0.000
Chapter XXII Codes for special purposes
0.751 0.249 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.749 0.251 0.000
I69 Sequelae of cerebrovascular disease
0.745 0.255 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.745 0.255 0.000
S90-S99 Injuries to the ankle and foot
0.742 0.258 0.000
I38 Endocarditis, valve unspecified
0.742 0.258 0.000
W20-W49 Exposure to inanimate mechanical forces
0.742 0.258 0.000
Y83.3 Surgical operation with formation of external stoma
0.741 0.259 0.000
T79-T79 Certain early complications of trauma
0.739 0.261 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.738 0.262 0.000
K08 Other disorders of teeth and supporting structures
0.738 0.262 0.000
R00.8 Other and unspecified abnormalities of heart beat
0.734 0.265 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.734 0.266 0.000
K85 Acute pancreatitis
0.733 0.267 0.000
S80-S89 Injuries to the knee and lower leg
0.732 0.268 0.000
K50-K52 Noninfective enteritis and colitis
0.731 0.268 0.000
T92.1 Sequelae of fracture of arm
0.731 0.269 0.000
M50 Cervical disk disorders
0.730 0.270 0.000
S02 Fracture of skull and facial bones
0.729 0.271 0.000
I51.8 Other ill-defined heart diseases
0.728 0.272 0.000
J36 Peritonsillar abscess
0.727 0.273 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.726 0.274 0.000
K75 Other inflammatory liver diseases
0.725 0.275 0.000
E20-E35 Disorders of other endocrine glands
0.724 0.275 0.000
K82.8 Other specified diseases of gallbladder
0.722 0.278 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.722 0.278 0.000
S00.9 Superficial injury of head, part unspecified
0.722 0.278 0.000
I50.1 Left ventricular failure
0.721 0.279 0.000
I49.0 Ventricular fibrillation and flutter
0.721 0.279 0.000
D50-D53 Nutritional anaemias
0.720 0.280 0.000
K11 Diseases of salivary glands
0.720 0.280 0.000
W19 Unspecified fall
0.719 0.281 0.000
I77 Other disorders of arteries and arterioles
0.718 0.282 0.000
M65-M68 Disorders of synovium and tendon
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I23 Certain current complications following acute myocardial infarction
0.717 0.283 0.000
J35 Chronic diseases of tonsils and adenoids
0.717 0.283 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.716 0.283 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.716 0.284 0.000
I25.6 Silent myocardial ischaemia
0.716 0.284 0.000
I25.5 Ischaemic cardiomyopathy
0.716 0.284 0.000
I25.4 Coronary artery aneurysm
0.716 0.284 0.000
I25.3 Aneurysm of heart
0.716 0.284 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.716 0.284 0.000
R50-R69 General symptoms and signs
0.716 0.284 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.716 0.284 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.716 0.284 0.000
Y35-Y36 Legal intervention and operations of war
0.716 0.284 0.000
Y10-Y34 Event of undetermined intent
0.716 0.284 0.000
Y00-Y09 Assault
0.716 0.284 0.000
X85-X99 Assault
0.716 0.284 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.716 0.284 0.000
X50-X57 Overexertion, travel and privation
0.716 0.284 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.716 0.284 0.000
X30-X39 Exposure to forces of nature
0.716 0.284 0.000
X20-X29 Contact with venomous animals and plants
0.716 0.284 0.000
X10-X19 Contact with heat and hot substances
0.716 0.284 0.000
X00-X09 Exposure to smoke, fire and flames
0.716 0.284 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.716 0.284 0.000
W75-W84 Other accidental threats to breathing
0.716 0.284 0.000
W65-W74 Accidental drowning and submersion
0.716 0.284 0.000
W50-W64 Exposure to animate mechanical forces
0.716 0.284 0.000
V98-V99 Other and unspecified transport accidents
0.716 0.284 0.000
V95-V97 Air and space transport accidents
0.716 0.284 0.000
V90-V94 Water transport accidents
0.716 0.284 0.000
V80-V89 Other land transport accidents
0.716 0.284 0.000
V70-V79 Bus occupant injured in transport accident
0.716 0.284 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.716 0.284 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.716 0.284 0.000
V40-V49 Car occupant injured in transport accident
0.716 0.284 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.716 0.284 0.000
V20-V29 Motorcycle rider injured in transport accident
0.716 0.284 0.000
V01-V09 Pedestrian injured in transport accident
0.716 0.284 0.000
I35.0 Aortic (valve) stenosis
0.716 0.284 0.000
I52 Other heart disorders in diseases classified elsewhere
0.715 0.285 0.000
I48 Atrial fibrillation and flutter
0.715 0.285 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.715 0.285 0.000
I41 Myocarditis in diseases classified elsewhere
0.715 0.285 0.000
I40 Acute myocarditis
0.715 0.285 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.715 0.285 0.000
I37 Pulmonary valve disorders
0.715 0.285 0.000
I36 Nonrheumatic tricuspid valve disorders
0.715 0.285 0.000
I33 Acute and subacute endocarditis
0.715 0.285 0.000
I32 Pericarditis in diseases classified elsewhere
0.715 0.285 0.000
M70-M79 Other soft tissue disorders
0.715 0.285 0.000
T66-T78 Other and unspecified effects of external causes
0.715 0.285 0.000
I08 Multiple valve diseases
0.714 0.286 0.000
R05 Cough
0.714 0.286 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.713 0.286 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.713 0.287 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.713 0.287 0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.713 0.287 0.000
T33-T35 Frostbite
0.713 0.287 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.713 0.287 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.713 0.287 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.713 0.287 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.713 0.287 0.000
T00-T07 Injuries involving multiple body regions
0.713 0.287 0.000
S10-S19 Injuries to the neck
0.713 0.287 0.000
I47.2 Ventricular tachycardia
0.712 0.288 0.000
S01.8 Open wound of other parts of head
0.712 0.288 0.000
S70-S79 Injuries to the hip and thigh
0.711 0.288 0.000
J60-J70 Lung diseases due to external agents
0.711 0.289 0.000
I45 Other conduction disorders
0.710 0.290 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.710 0.290 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.710 0.290 0.000
I72 Other aneurysm
0.707 0.293 0.000
R01 Cardiac murmurs and other cardiac sounds
0.706 0.294 0.000
J37 Chronic laryngitis and laryngotracheitis
0.705 0.294 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.705 0.294 0.000
I49.8 Other specified cardiac arrhythmias
0.705 0.295 0.000
I10-I15 Hypertensive diseases
0.705 0.295 0.000
K12 Stomatitis and related lesions
0.705 0.295 0.000
I78 Diseases of capillaries
0.704 0.296 0.000
I49.9 Cardiac arrhythmia, unspecified
0.704 0.296 0.000
V10-V19 Pedal cyclist injured in transport accident
0.703 0.297 0.000
D69 Purpura and other haemorrhagic conditions
0.703 0.297 0.000
S06.3 Focal brain injury
0.702 0.297 0.000
J34.1 Cyst and mucocele of nose and nasal sinus
0.702 0.298 0.000
J34.0 Abscess, furuncle and carbuncle of nose
0.702 0.298 0.000
O26 Maternal care for other conditions predominantly related to pregnancy
0.702 0.298 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.701 0.299 0.000
Chapter I Certain infectious and parasitic diseases
0.700 0.300 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.700 0.300 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.700 0.300 0.000
G30-G32 Other degenerative diseases of the nervous system
0.699 0.301 0.000
I21.4 Acute subendocardial myocardial infarction
0.697 0.303 0.000
T93 Sequelae of injuries of lower limb
0.697 0.303 0.000
S01.3 Open wound of ear
0.697 0.303 0.000
I50.9 Heart failure, unspecified
0.697 0.303 0.000
K81.8 Other cholecystitis
0.697 0.303 0.000
Y83.9 Surgical procedure, unspecified
0.697 0.303 0.000
Y83.5 Amputation of limb(s)
0.697 0.303 0.000
Y83.0 Surgical operation with transplant of whole organ
0.697 0.303 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.696 0.304 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.695 0.305 0.000
S08 Traumatic amputation of part of head
0.693 0.307 0.000
S07 Crushing injury of head
0.693 0.307 0.000
S05 Injury of eye and orbit
0.693 0.307 0.000
S04 Injury of cranial nerves
0.693 0.307 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.693 0.307 0.000
O34.2 Maternal care due to uterine scar from previous surgery
0.692 0.308 0.000
R06.0 Dyspnoea
0.692 0.308 0.000
K04 Diseases of pulp and periapical tissues
0.691 0.309 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.691 0.309 0.000
R06.2 Wheezing
0.691 0.309 0.000
R55 Syncope and collapse
0.691 0.309 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.690 0.310 0.000
E14 Unspecified diabetes mellitus
0.689 0.311 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.689 0.311 0.000
Y88 Sequelae of surgical and medical care as external cause
0.688 0.312 0.000
H60-H62 Diseases of external ear
0.688 0.312 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.687 0.313 0.000
J39 Other diseases of upper respiratory tract
0.687 0.313 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.686 0.314 0.000
S20-S29 Injuries to the thorax
0.686 0.314 0.000
O36.8 Maternal care for other specified foetal problems
0.685 0.314 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.685 0.315 0.000
Y83.4 Other reconstructive surgery
0.684 0.316 0.000
H72 Perforation of tympanic membrane
0.683 0.317 0.000
T90.2 Sequelae of fracture of skull and facial bones
0.683 0.317 0.000
I61 Intracerebral haemorrhage
0.681 0.319 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.680 0.320 0.000
R06.7 Sneezing
0.680 0.320 0.000
R06.6 Hiccough
0.680 0.320 0.000
R06.4 Hyperventilation
0.680 0.320 0.000
R06.3 Periodic breathing
0.680 0.320 0.000
R06.1 Stridor
0.680 0.320 0.000
D60-D64 Aplastic and other anaemias
0.679 0.321 0.000
J32.2 Chronic ethmoidal sinusitis
0.679 0.321 0.000
O47 False labour
0.679 0.321 0.000
C18 Malignant neoplasm of colon
0.677 0.323 0.000
G20-G26 Extrapyramidal and movement disorders
0.677 0.323 0.000
S01.1 Open wound of eyelid and periocular area
0.677 0.323 0.000
K74.5 Biliary cirrhosis, unspecified
0.677 0.323 0.000
K80.3 Calculus of bile duct with cholangitis
0.677 0.323 0.000
K80.8 Other cholelithiasis
0.677 0.323 0.000
I63.8 Other cerebral infarction
0.677 0.323 0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.677 0.323 0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.677 0.323 0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.677 0.323 0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.677 0.323 0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.677 0.323 0.000
I35.1 Aortic (valve) insufficiency
0.676 0.324 0.000
K72.0 Acute and subacute hepatic failure
0.676 0.324 0.000
K80.4 Calculus of bile duct with cholecystitis
0.676 0.324 0.000
K35-K38 Diseases of appendix
0.676 0.324 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.675 0.324 0.000
Y52 Agents primarily affecting the cardiovascular system
0.675 0.325 0.000
I49.4 Other and unspecified premature depolarisation
0.674 0.325 0.000
I49.2 Junctional premature depolarisation
0.674 0.325 0.000
I49.1 Atrial premature depolarisation
0.674 0.325 0.000
H73 Other disorders of tympanic membrane
0.675 0.325 0.000
I44.6 Other and unspecified fascicular block
0.673 0.327 0.000
I44.5 Left posterior fascicular block
0.673 0.327 0.000
I44.4 Left anterior fascicular block
0.673 0.327 0.000
I44.3 Other and unspecified atrioventricular block
0.673 0.327 0.000
K86.3 Pseudocyst of pancreas
0.673 0.327 0.000
J98.1 Pulmonary collapse
0.672 0.328 0.000
T81 Complications of procedures, not elsewhere classified
0.671 0.329 0.000
T84.1 Mechanical complication of internal fixation device of bones of limb
0.671 0.329 0.000
K80.1 Calculus of gallbladder with other cholecystitis
0.670 0.330 0.000
C51-C58 Malignant neoplasms of female genital organs
0.670 0.330 0.000
K77 Liver disorders in diseases classified elsewhere
0.670 0.330 0.000
K73 Chronic hepatitis, not elsewhere classified
0.670 0.330 0.000
K71 Toxic liver disease
0.670 0.330 0.000
G95 Other diseases of spinal cord
0.668 0.331 0.000
M45-M49 Spondylopathies
0.668 0.331 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.668 0.332 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.668 0.332 0.000
M06 Other rheumatoid arthritis
0.667 0.333 0.000
I44.1 Atrioventricular block, second degree
0.667 0.333 0.000
R18 Ascites
0.666 0.334 0.000
I25.2 Old myocardial infarction
0.666 0.334 0.000
T87 Complications peculiar to reattachment and amputation
0.665 0.334 0.000
T86 Failure and rejection of transplanted organs and tissues
0.665 0.334 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.665 0.334 0.000
S01.9 Open wound of head, part unspecified
0.665 0.335 0.000
I42.2 Other hypertrophic cardiomyopathy
0.665 0.335 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.664 0.336 0.000
G91 Hydrocephalus
0.663 0.337 0.000
G70-G73 Diseases of myoneural junction and muscle
0.663 0.337 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.663 0.337 0.000
T98 Sequelae of other and unspecified effects of external causes
0.661 0.339 0.000
T95 Sequelae of burns, corrosions and frostbite
0.661 0.339 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.661 0.339 0.000
T91 Sequelae of injuries of neck and trunk
0.661 0.339 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.661 0.339 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.661 0.339 0.000
H69 Other disorders of Eustachian tube
0.661 0.339 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.660 0.340 0.000
I67.7 Cerebral arteritis, not elsewhere classified
0.659 0.341 0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.659 0.341 0.000
I67.5 Moyamoya disease
0.659 0.341 0.000
I67.4 Hypertensive encephalopathy
0.659 0.341 0.000
I67.3 Progressive vascular leukoencephalopathy
0.659 0.341 0.000
I67.0 Dissection of cerebral arteries, nonruptured
0.659 0.341 0.000
W19.9 Unspecified place
0.659 0.341 0.000
I51.9 Heart disease, unspecified
0.656 0.344 0.000
K74.3 Primary biliary cirrhosis
0.656 0.344 0.000
J20-J22 Other acute lower respiratory infections
0.656 0.344 0.000
G50 Disorders of trigeminal nerve
0.656 0.344 0.000
G81 Hemiplegia
0.656 0.344 0.000
H91 Other hearing loss
0.654 0.346 0.000
Y40 Systemic antibiotics
0.653 0.347 0.000
O85-O92 Complications predominantly related to the puerperium
0.653 0.347 0.000
M81 Osteoporosis without pathological fracture
0.653 0.347 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.653 0.347 0.000
Y89 Sequelae of other external causes
0.651 0.348 0.000
Y87 Sequelae of intentional self-harm, assault and events of undetermined intent
0.651 0.348 0.000
O00-O08 Pregnancy with abortive outcome
0.649 0.351 0.000
J00-J06 Acute upper respiratory infections
0.648 0.352 0.000
M86-M90 Other osteopathies
0.648 0.352 0.000
O30 Multiple gestation
0.648 0.352 0.000
H71 Cholesteatoma of middle ear
0.648 0.352 0.000
H81 Disorders of vestibular function
0.648 0.352 0.000
I22.1 Subsequent myocardial infarction of inferior wall
0.647 0.353 0.000
R03.1 Nonspecific low blood-pressure reading
0.647 0.353 0.000
C34 Malignant neoplasm of bronchus and lung
0.646 0.354 0.000
M91-M94 Chondropathies
0.646 0.354 0.000
M60-M63 Disorders of muscles
0.646 0.354 0.000
M00-M03 Infectious arthropathies
0.646 0.354 0.000
K08.9 Disorder of teeth and supporting structures, unspecified
0.645 0.355 0.000
K05 Gingivitis and periodontal diseases
0.645 0.355 0.000
D80-D89 Certain disorders involving the immune mechanism
0.645 0.355 0.000
G51 Facial nerve disorders
0.643 0.357 0.000
R26 Abnormalities of gait and mobility
0.643 0.357 0.000
I46 Cardiac arrest
0.642 0.358 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.641 0.358 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.640 0.360 0.000
J33.8 Other polyp of sinus
0.640 0.360 0.000
O36.5 Maternal care for poor foetal growth
0.640 0.360 0.000
M50.2 Other cervical disk displacement
0.639 0.361 0.000
I70 Atherosclerosis
0.639 0.361 0.000
R02 Gangrene, not elsewhere classified
0.638 0.362 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.638 0.362 0.000
D69.6 Thrombocytopenia, unspecified
0.638 0.362 0.000
I60 Subarachnoid haemorrhage
0.636 0.363 0.000
K50 Crohn's disease [regional enteritis]
0.636 0.364 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.634 0.366 0.000
D55-D59 Haemolytic anaemias
0.634 0.366 0.000
Y85 Sequelae of transport accidents
0.633 0.366 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.633 0.367 0.000
K86.0 Alcohol-induced chronic pancreatitis
0.632 0.368 0.000
S00.1 Contusion of eyelid and periocular area
0.632 0.368 0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.632 0.368 0.000
R10.4 Other and unspecified abdominal pain
0.631 0.369 0.000
K10 Other diseases of jaws
0.631 0.369 0.000
K09 Cysts of oral region, not elsewhere classified
0.631 0.369 0.000
K07 Dentofacial anomalies [including malocclusion]
0.631 0.369 0.000
K06 Other disorders of gingiva and edentulous alveolar ridge
0.631 0.369 0.000
K03 Other diseases of hard tissues of teeth
0.631 0.369 0.000
K00 Disorders of tooth development and eruption
0.631 0.369 0.000
R10.1 Pain localised to upper abdomen
0.631 0.369 0.000
K14 Diseases of tongue
0.629 0.371 0.000
K76.8 Other specified diseases of liver
0.628 0.372 0.000
S06.5 Traumatic subdural haemorrhage
0.628 0.372 0.000
E78.5 Hyperlipidaemia, unspecified
0.627 0.373 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.626 0.374 0.000
I47.1 Supraventricular tachycardia
0.626 0.374 0.000
J31.2 Chronic pharyngitis
0.626 0.374 0.000
J31.1 Chronic nasopharyngitis
0.626 0.374 0.000
I24.1 Dressler's syndrome
0.626 0.374 0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.626 0.374 0.000
J09-J18 Influenza and pneumonia
0.626 0.374 0.000
J32.9 Chronic sinusitis, unspecified
0.625 0.375 0.000
M50.1 Cervical disk disorder with radiculopathy
0.625 0.375 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.625 0.375 0.000
R76 Other abnormal immunological findings in serum
0.625 0.375 0.000
Y59 Other and unspecified vaccines and biological substances
0.624 0.376 0.000
Y58 Bacterial vaccines
0.624 0.376 0.000
Y57 Other and unspecified drugs and medicaments
0.624 0.376 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.624 0.376 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.624 0.376 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.624 0.376 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.624 0.376 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.624 0.376 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.624 0.376 0.000
Y48 Anaesthetics and therapeutic gases
0.624 0.376 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.624 0.376 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.624 0.376 0.000
Y44 Agents primarily affecting blood constituents
0.624 0.376 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.624 0.376 0.000
E40-E46 Malnutrition
0.624 0.376 0.000
H66 Suppurative and unspecified otitis media
0.622 0.377 0.000
Y45.1 Salicylates
0.622 0.377 0.000
T81.4 Infection following a procedure, not elsewhere classified
0.622 0.378 0.000
I20.1 Angina pectoris with documented spasm
0.622 0.378 0.000
I67.1 Cerebral aneurysm, nonruptured
0.621 0.378 0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft
0.620 0.379 0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts
0.620 0.379 0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts
0.620 0.379 0.000
T84.3 Mechanical complication of other bone devices, implants and grafts
0.620 0.379 0.000
T84.2 Mechanical complication of internal fixation device of other bones
0.620 0.379 0.000
O36.6 Maternal care for excessive foetal growth
0.619 0.381 0.000
K11.2 Sialoadenitis
0.619 0.381 0.000
S09.9 Unspecified injury of head
0.619 0.381 0.000
O26.8 Other specified pregnancy-related conditions
0.619 0.381 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.618 0.382 0.000
D10-D36 Benign neoplasms
0.618 0.382 0.000
K82.4 Cholesterolosis of gallbladder
0.617 0.383 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.616 0.383 0.000
J96 Respiratory failure, not elsewhere classified
0.616 0.383 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.616 0.383 0.000
M65 Synovitis and tenosynovitis
0.616 0.384 0.000
J38.7 Other diseases of larynx
0.616 0.384 0.000
R49 Voice disturbances
0.616 0.384 0.000
I20.9 Angina pectoris, unspecified
0.616 0.384 0.000
S06.30 Focal brain injury (without open intracranial wound)
0.616 0.384 0.000
S01.7 Multiple open wounds of head
0.615 0.384 0.000
S01.4 Open wound of cheek and temporomandibular area
0.615 0.384 0.000
S01.2 Open wound of nose
0.615 0.384 0.000
K65-K67 Diseases of peritoneum
0.615 0.385 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.615 0.385 0.000
D50 Iron deficiency anaemia
0.615 0.385 0.000
O45 Premature separation of placenta [abruptio placentae]
0.614 0.386 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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